How to Trip Rapid Review

Step 1: Select articles relevant to your search (remember the system is only optimised for single intervention studies)

Step 2: press

Step 3: review the result, and maybe amend the or if you know better! If we're unsure of the overall sentiment of the trial we will display the conclusion under the article title. We then require you to tell us what the correct sentiment is.

28,621 results for

Wound Infection

by
...
Latest & greatest
Alerts

Export results

Use check boxes to select individual results below

SmartSearch available

Trip's SmartSearch engine has discovered connected searches & results. Click to show

181. Prophylactic incisional negative pressure wound therapy reduces the risk of surgical site infection after caesarean section in obese women: a pragmatic randomised clinical trial. (PubMed)

Prophylactic incisional negative pressure wound therapy reduces the risk of surgical site infection after caesarean section in obese women: a pragmatic randomised clinical trial. To evaluate the reduction of surgical site infections by prophylactic incisional negative pressure wound therapy compared with standard postoperative dressings in obese women giving birth by caesarean section.Multicentre randomised controlled trial.Five hospitals in Denmark.Obese women (prepregnancy body mass index (...) (BMI) ≥30 kg/m2 ) undergoing elective or emergency caesarean section.The participants were randomly assigned to incisional negative pressure wound therapy or a standard dressing after caesarean section and analysed by intention-to-treat. Blinding was not possible due to the nature of the intervention.The primary outcome was surgical site infection requiring antibiotic treatment within the first 30 days after surgery. Secondary outcomes included wound exudate, dehiscence and health-related quality

2018 BJOG : an international journal of obstetrics and gynaecology

182. Comparison of Superficial Surgical Site Infection Between Delayed Primary Versus Primary Wound Closure in Complicated Appendicitis: A Randomized Controlled Trial. (PubMed)

Comparison of Superficial Surgical Site Infection Between Delayed Primary Versus Primary Wound Closure in Complicated Appendicitis: A Randomized Controlled Trial. To compare superficial surgical site infection (SSI) rates between delayed primary wound closure (DPC) and primary wound closure (PC) for complicated appendicitis.SSI is common in appendectomy for complicated appendicitis. DPC is preferentially used over PC, but its efficacy is still controversial.A multicenter randomized controlled (...) trial was conducted in 6 hospitals in Thailand, enrolling patients with gangrenous and ruptured appendicitis. Patients were randomized to PC (ie, immediately wound closure) or DPC (ie, wound closure at postoperative days 3-5). Superficial SSI was defined by the Center for Disease Control criteria. Secondary outcomes included postoperative pain, length of stay, recovery time, quality of life, and cost of treatment.In all, 303 and 304 patients were randomized to PC and DPC groups, and 5 and 4 patients

2018 Annals of Surgery

183. Use of Closed Incisional Negative Pressure Wound Therapy After Revision Total Hip and Knee Arthroplasty in Patients at High Risk for Infection: A Prospective, Randomized Clinical Trial. (PubMed)

Use of Closed Incisional Negative Pressure Wound Therapy After Revision Total Hip and Knee Arthroplasty in Patients at High Risk for Infection: A Prospective, Randomized Clinical Trial. Continuous wound drainage after arthroplasty can lead to the development of a periprosthetic joint infection. Closed incisional negative pressure wound therapy (ciNPWT) has been reported to help alleviate drainage and other wound complications. The purpose of this prospective randomized controlled trial (...) joint infection and inflammatory arthritis, the ciNPWT cohort had a significantly decreased wound complication rate (odds ratio 0.28, 95% confidence interval 0.11-0.68).ciNPWT may decrease the rate of postoperative wound complications in patients who are at an increased risk of such wound issues after revision arthroplasty.Copyright © 2019 The Authors. Published by Elsevier Inc. All rights reserved.

2018 Journal of Arthroplasty

184. Negative Pressure Wound Therapy for Surgical-site Infections: A Randomized Trial. (PubMed)

Negative Pressure Wound Therapy for Surgical-site Infections: A Randomized Trial. This study seeks to evaluate the efficacy of negative pressure wound therapy for surgical-site infection (SSI) after open pancreaticoduodenectomy.Despite improvement in infection control, SSIs remain a common cause of morbidity after abdominal surgery. SSI has been associated with an increased risk of reoperation, prolonged hospitalization, readmission, and higher costs. Recent retrospective studies have suggested (...) that the use of negative pressure wound therapy can potentially prevent this complication.We conducted a single-center randomized, controlled trial evaluating surgical incision closure during pancreaticoduodenectomy using negative pressure wound therapy in patients at high risk for SSI. We randomly assigned patients to receive negative pressure wound therapy or a standard wound closure. The primary end point of the study was the occurrence of a postoperative SSI. We evaluated the economic impact

2018 Annals of Surgery

185. Prophylactic incisional negative pressure wound therapy reduces the risk of surgical site infection after caesarean section in obese women: A pragmatic randomised clinical trial. (PubMed)

Prophylactic incisional negative pressure wound therapy reduces the risk of surgical site infection after caesarean section in obese women: A pragmatic randomised clinical trial. To evaluate the reduction of surgical site infections by prophylactic incisional negative pressure wound therapy compared with standard postoperative dressings in obese women giving birth by caesarean section.Multicentre randomised controlled trial.Five hospitals in Denmark.Obese women (prepregnancy body mass index (...) (BMI) ≥30 kg/m2 ) undergoing elective or emergency caesarean section.The participants were randomly assigned to incisional negative pressure wound therapy or a standard dressing after caesarean section and analysed by intention-to-treat. Blinding was not possible due to the nature of the intervention.The primary outcome was surgical site infection requiring antibiotic treatment within the first 30 days after surgery. Secondary outcomes included wound exudate, dehiscence and health-related quality

2018 BJOG

186. Prognostic value of the Society for Vascular Surgery Wound, Ischemia, and foot Infection (WIfI) classification in patients with no-option chronic limb-threatening ischemia. (PubMed)

Prognostic value of the Society for Vascular Surgery Wound, Ischemia, and foot Infection (WIfI) classification in patients with no-option chronic limb-threatening ischemia. The Wound, Ischemia, and foot Infection (WIfI) classification was developed to assess amputation risk and hence to aid in clinical decision-making in patients with chronic limb-threatening ischemia (CLTI). WIfI has been validated in multiple CLTI cohorts worldwide. In this study, we examined the relationship between WIfI (...) is the first study to demonstrate that WIfI classification is associated with important clinical outcomes in a no-option CLTI population. Our data suggest that limb prognosis is poor in patients with classic ischemic rest pain, without wounds or infection (W0-I3-fI0), when they lack revascularization options. Further studies are needed to determine whether reassignment of this population from WIfI stage 2 to WIfI stage 3 may be appropriate to reflect amputation risk in the absence of successful

2018 Journal of Vascular Surgery

187. Negative Pressure Wound Therapy for Surgical-site Infections: A Randomized Trial. (PubMed)

Negative Pressure Wound Therapy for Surgical-site Infections: A Randomized Trial. This study seeks to evaluate the efficacy of negative pressure wound therapy for surgical-site infection (SSI) after open pancreaticoduodenectomy.Despite improvement in infection control, SSIs remain a common cause of morbidity after abdominal surgery. SSI has been associated with an increased risk of reoperation, prolonged hospitalization, readmission, and higher costs. Recent retrospective studies have suggested (...) that the use of negative pressure wound therapy can potentially prevent this complication.We conducted a single-center randomized, controlled trial evaluating surgical incision closure during pancreaticoduodenectomy using negative pressure wound therapy in patients at high risk for SSI. We randomly assigned patients to receive negative pressure wound therapy or a standard wound closure. The primary end point of the study was the occurrence of a postoperative SSI. We evaluated the economic impact

2018 Annals of Surgery

188. Effect of Negative Pressure Wound Therapy vs Standard Wound Management on 12-Month Disability Among Adults With Severe Open Fracture of the Lower Limb: The WOLLF Randomized Clinical Trial. (PubMed)

Effect of Negative Pressure Wound Therapy vs Standard Wound Management on 12-Month Disability Among Adults With Severe Open Fracture of the Lower Limb: The WOLLF Randomized Clinical Trial. Open fractures of the lower limb occur when a broken bone penetrates the skin. There can be major complications from these fractures, which can be life-changing.To assess the disability, rate of deep infection, and quality of life in patients with severe open fracture of the lower limb treated with negative (...) solid foam or gauze was placed over the surface of the wound and connected to a suction pump, creating a partial vacuum over the dressing, vs standard dressings not involving application of negative pressure (n = 234).Disability Rating Index score (range, 0 [no disability] to 100 [completely disabled]) at 12 months was the primary outcome measure, with a minimal clinically important difference of 8 points. Secondary outcomes were complications including deep infection and quality of life (score

Full Text available with Trip Pro

2018 JAMA

189. Open vs Closed Negative Pressure Wound Therapy for Contaminated and Dirty Surgical Wounds: A Prospective Randomized Comparison

consented preoperatively, but not entered nor assigned treatment until intraoperative findings were known. Patients were randomly assigned to either open-NPWT or a wound closed with skin staples and external closed-NPWT. Primary outcome was time to complete wound healing, defined as complete epithelization of the wound. Secondary outcomes were wound complications including wound infection, seroma, and dehiscence. Statistical analysis was performed using chi-square test, Fisher exact test, t-test (...) , and Wilcoxon Rank-Sum test with significance of p < 0.05.Twenty-five closed-NPWT and 24 open-NPWT patients were analyzed. There were no significant differences in sex, mean age, BMI, smoking history, steroid use, comorbidities, or indication for surgery in the 2 groups. One patient in the open-NPWT group and 2 patients in the closed-NPWT group developed a wound infection (p = 1.0). Four open-NPWT and 3 closed-NPWT patients died from complications unrelated to the wound. Wound healing occurred at a median

2018 EvidenceUpdates

190. Negative pressure wound therapy for skin grafts and surgical wounds healing by primary intention. (PubMed)

or high risk of bias for one or more of the quality indicators we assessed. Seven trials compared NPWT with a standard dressing (two of these were 'home-made' NPWT devices), one trial compared one 'home-made' NPWT with a commercially available device. In trials where the individual was the unit of randomisation, there were no differences in the incidence of surgical site infections (SSI); wound dehiscence, re-operation (in incisional wounds); seroma/haematoma; or failed skin grafts. Lower re-operation (...) Negative pressure wound therapy for skin grafts and surgical wounds healing by primary intention. Indications for the use of negative pressure wound therapy (NPWT) are broadening with a range of systems now available on the market, including those designed for use on clean, closed incisions and skin grafts. Reviews have concluded that the evidence for the effectiveness of NPWT remains uncertain, however, it is a rapidly evolving therapy. Consequently, an updated systematic review

Full Text available with Trip Pro

2014 Cochrane

191. Prophylactic Negative Pressure Wound Therapy and Wound Complication After Cesarean Delivery in Women With Class II or III Obesity: A Randomized Controlled Trial

Prophylactic Negative Pressure Wound Therapy and Wound Complication After Cesarean Delivery in Women With Class II or III Obesity: A Randomized Controlled Trial To compare the occurrence of superficial surgical site infections in obese women using prophylactic negative pressure therapy with standard dressings after cesarean delivery.We conducted a randomized controlled, nonblinded, two-center study of prophylactic negative pressure therapy compared with standard surgical dressings placed (...) January 5, 2015, and January 7, 2017, from two sites. The mean BMI on admission was 44.9 (±8) for the prophylactic negative wound therapy group and 43.4 (±7) for the standard dressing group. There were no differences in the occurrence of observed superficial surgical site infections between women using prophylactic negative pressure wound therapy (12/80 [15%]) compared with women who received the standard dressing (8/81 [10%], P=.35, relative risk 1.52, 95% CI 0.66-3.52). There were no differences

2018 EvidenceUpdates

192. PICO negative pressure wound dressings for closed surgical incisions

surgical incisions in the NHS. They are associated with fewer surgical site infections and seromas compared with standard wound dressings. 1.2 PICO negative pressure wound dressings should be considered as an option for closed surgical incisions in people who are at high risk of developing surgical site infections. Risk factors for surgical site infections are described in section 4.2. 1.3 Cost modelling suggests that PICO negative pressure wound dressings provide extra clinical benefits at a similar (...) overall cost compared with standard wound dressings. Wh Why the committee made these recommendations y the committee made these recommendations PICO negative pressure wound dressings are designed to allow an even distribution of negative pressure on the surface of a closed surgical incision. The system is also designed to be portable. Clinical evidence shows that using PICO dressings for closed surgical incisions can lead to fewer surgical site infections. Evidence also shows that using PICO dressings

2019 National Institute for Health and Clinical Excellence - Medical technologies

193. Negative Pressure Wound Therapy (NPWT)

: pressure ulcers; venous leg ulcers; burns; open traumatic wounds; open abdomen; wounds healing by primary intention (including split-thickness skin grafts, caesarean section wounds and closed incision wounds); surgical wounds healing by secondary intention; and sternal wound infections after cardiothoracic surgery. Consensus statements to guide best practice • Exploratory work by SHTG highlighted the need for guidance on the appropriate and safe use of NPWT in NHSScotland. Therefore consensus (...) research to consolidate the existing evidence. Trauma wounds ? For open fracture wounds, a good quality systematic review reported no statistically significant difference between NPWT and standard care in the proportion of wounds healed at 6 weeks (based on one robust RCT). ? The same systematic review concluded that it was uncertain whether there was a difference in risk of wound infection, adverse events, time to closure or coverage surgery, pain or health-related quality of life between NPWT

2019 SHTG Advice Statements

194. Effects of Aloe Vera and Chitosan Nanoparticle Thin-Film Membranes on Wound Healing in Full Thickness Infected Wounds with Methicillin Resistant Staphylococcus Aureus (PubMed)

Effects of Aloe Vera and Chitosan Nanoparticle Thin-Film Membranes on Wound Healing in Full Thickness Infected Wounds with Methicillin Resistant Staphylococcus Aureus To assess effect of Aleo vera with chitosan nanoparticle biofilm on wound healing in full thickness infected wounds with antibiotic resistant gram positive bacteria.Thirty rats were randomized into five groups of six rats each. Group I: Animals with uninfected wounds treated with 0.9% saline solution. Group II: Animals (...) with infected wounds treated with saline. Group III: Animals with infected wounds were dressed with chitosan nanoparticle thin-film membranes. Group IV: Animals with infected wounds were treated topically with Aloe vera and Group V: Animals with infected wounds were treated topically with Aloe vera and dressed with chitosan nanoparticle thin-film membranes. Wound size was measured on 6, 9, 12, 15, 18 and 21days after surgery.Microbiology, reduction in wound area and hydroxyproline contents indicated

Full Text available with Trip Pro

2018 Bulletin of emergency & trauma

195. Mixing two different propolis samples potentiates their antimicrobial activity and wound healing property: A novel approach in wound healing and infection (PubMed)

Mixing two different propolis samples potentiates their antimicrobial activity and wound healing property: A novel approach in wound healing and infection The study aimed to investigate whether mixing two different propolis samples can potentiate their biological activity. This hypothesis was tested by studying the effect of mixed propolis on microbial growth and wound healing and compared with the effect of each propolis individually.The effect of mixing two different propolis extracts (...) (A and B) collected from different locations in Iraq on Escherichia coli, Staphylococcus aureus, and Candida albicans was studied by minimum inhibitory concentration assessment and compared with the effect of each propolis. Wound healing effect of the mixed propolis was studied. Twenty-four rabbits were used for the experiment, and they were assigned to four groups. Wounds were created on the dorsum of each rabbit and treated by topical application of 1 mL of either mixed propolis, propolis

Full Text available with Trip Pro

2018 Veterinary world

196. Wound healing and infection in surgery. The clinical impact of smoking and smoking cessation: a systematic review and meta-analysis

Wound healing and infection in surgery. The clinical impact of smoking and smoking cessation: a systematic review and meta-analysis Wound healing and infection in surgery. The clinical impact of smoking and smoking cessation: a systematic review and meta-analysis Wound healing and infection in surgery. The clinical impact of smoking and smoking cessation: a systematic review and meta-analysis Sorensen LT CRD summary The authors concluded that across all specialties smokers had a higher (...) of perioperative smoking cessation on postoperative healing complications were also eligible. Trials with more than 40% drop-out were excluded. Eligible outcomes included all types of adverse healing events after surgical procedures with access through a skin incision, short-term healing outcomes (wound and tissue flap necrosis, healing delay, dehiscence of wounds and sutured tissue, surgical site infections, non-specified wound complications) and long-term healing outcomes (hernias and lack of fistula or bone

Full Text available with Trip Pro

2012 DARE.

197. Wound protectors reduce surgical site infection: a meta-analysis of randomized controlled trials

Wound protectors reduce surgical site infection: a meta-analysis of randomized controlled trials Wound protectors reduce surgical site infection: a meta-analysis of randomized controlled trials Wound protectors reduce surgical site infection: a meta-analysis of randomized controlled trials Edwards JP, Ho AL, Tee MC, Dixon E, Ball CG CRD summary The authors concluded that wound protectors reduced the rate of surgical site infection after gastrointestinal or biliary tract surgery (...) , and they recommended their routine use in clinical practice. This was a well-conducted review, and the authors' conclusions seem reliable. Authors' objectives To evaluate whether wound protectors reduce the risk of surgical site infection, in patients undergoing gastrointestinal or biliary tract surgery. Searching MEDLINE, EMBASE, and Cochrane Central Register of Controlled Trials (CENTRAL) were searched from inception to March 2011, without limits on language or publication status. Search terms were reported

2012 DARE.

198. Systematic review of the clinical effectiveness of wound-edge protection devices in reducing surgical site infection in patients undergoing open abdominal surgery

Systematic review of the clinical effectiveness of wound-edge protection devices in reducing surgical site infection in patients undergoing open abdominal surgery Systematic review of the clinical effectiveness of wound-edge protection devices in reducing surgical site infection in patients undergoing open abdominal surgery. Systematic review of the clinical effectiveness of wound-edge protection devices in reducing surgical site infection in patients undergoing open abdominal surgery. Gheorghe (...) A, Calvert M, Pinkney TD, Fletcher BR, Bartlett DC, Hawkins WJ, Mak T, Youssef H, Wilson S CRD summary This review concluded that wound–edge protection devices may have been efficient for reducing postoperative surgical site infections in patients who underwent open abdominal surgery, compared with standard care. The poor quality of the evidence indicated a need for a large good quality randomised controlled trial. This seems a reliable conclusion from a well-conducted review. Authors' objectives

2012 DARE.

199. Does this patient have an infection of a chronic wound?

Does this patient have an infection of a chronic wound? Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2012 DARE.

200. Closure methods for laparotomy incisions for preventing incisional hernias and other wound complications. (PubMed)

with multifilament sutures (RR 0.76, 95% CI 0.59 to 0.98, I2 = 30%, moderate-quality evidence).For our secondary outcomes, we found that none of the interventions reduced the risk of wound infection, whether based on suture absorption (absorbable versus non-absorbable sutures, RR 0.99, 95% CI 0.84 to 1.17, moderate-quality evidence; or slow versus fast absorbable sutures, RR 1.16, 95% CI 0.85 to 1.57, moderate-quality evidence), closure method (mass versus layered, RR 0.93, 95% CI 0.67 to 1.30, low-quality (...) Closure methods for laparotomy incisions for preventing incisional hernias and other wound complications. Surgeons who perform laparotomy have a number of decisions to make regarding abdominal closure. Material and size of potential suture types varies widely. In addition, surgeons can choose to close the incision in anatomic layers or mass ('en masse'), as well as using either a continuous or interrupted suturing technique, of which there are different styles of each. There is ongoing debate

Full Text available with Trip Pro

2017 Cochrane

To help you find the content you need quickly, you can filter your results via the categories on the right-hand side >>>>