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Work-Related Eye Injury

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161. Facial Trauma, Sports-Related Injuries

injury are motor vehicle accidents, domestic accidents, work-related accidents, violence, and sports. The causes vary in association with age, sex, race, socioeconomic status, and geographic location. [ , , ] Sports-related facial injuries account for 8% of all facial soft tissue injuries, with approximately 11-40% of all sports injuries involving the face. Injuries are most often due to direct hits with a ball or player-to-player contact. [ , ] In younger age groups, sports accidents have risen due (...) injury. Orbital Fractures One third of all orbital fractures are secondary to sports injuries [ ] and can almost always be prevented with the use of protective eyewear. The risk of injury to the eye is highly related to the type of sport. High-risk sports are those with high-speed projectile objects, clubs, or aggressive body contacts. Examination and diagnosis When an injury occurs near the eye, a thorough eye examination should be performed, as previously described. A circumferential bony framework

2014 eMedicine Surgery

162. TIMING INFLUENCE ON OUTCOMES OF VITRECTOMY FOR OPEN-GLOBE INJURY: A Prospective Randomized Comparative Study. (PubMed)

vitrectomy after open-globe injury leads to better anatomical and functional outcomes.This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. (...) TIMING INFLUENCE ON OUTCOMES OF VITRECTOMY FOR OPEN-GLOBE INJURY: A Prospective Randomized Comparative Study. To compare the impact of surgical timing on anatomical and functional outcomes of vitrectomy for open-globe injury.Fifty-three patients were entered into this prospective open-label study, with 26 patients randomized into early surgery group (vitrectomy conducted within 4 days) and 27 into delayed surgery group (vitrectomy performed between 10-14 days after injury). Six-month data were

2019 Retina (Philadelphia, Pa.) Controlled trial quality: uncertain

163. PARP Inhibitor Protects Against Chronic Hypoxia/Reoxygenation-Induced Retinal Injury by Regulation of MAPKs, HIF1α, Nrf2, and NFκB. (Full text)

PARP Inhibitor Protects Against Chronic Hypoxia/Reoxygenation-Induced Retinal Injury by Regulation of MAPKs, HIF1α, Nrf2, and NFκB. In the eye, chronic hypoxia/reoxygenation (H/R) contributes to the development of a number of ocular disorders. H/R induces the production of reactive oxygen species (ROS), leading to poly(ADP-ribose) polymerase-1 (PARP1) activation that promotes inflammation, cell death, and disease progression. Here, we analyzed the protective effects of the PARP1 inhibitor (...) olaparib in H/R-induced retina injury and investigated the signaling mechanisms involved.A rat retinal H/R model was used to detect histologic and biochemical changes in the retina.H/R induced reductions in the thickness of most retinal layers, which were prevented by olaparib. Furthermore, H/R caused increased levels of Akt and glycogen synthase kinase-3β phosphorylation, which were further increased by olaparib, contributing to retina protection. By contrast, H/R-induced c-Jun N-terminal kinase

2019 Investigative Ophthalmology & Visual Science

164. Effect of time to primary repair on final visual outcome after open globe injury. (Full text)

is a retrospective comparative case series including all open globe injuries presenting to the Birmingham Midland Eye Centre between 1 January 2014 and 15 March 2016. Presenting features, mechanism of injury, visual acuity at 6-12 months and demographic data were examined.56 open globe injuries were repaired, of which sufficient data for analysis were available on 52 cases. The mean time to primary repair was 1 day after injury (range 5 hours to 7 days). Final visual acuity at 6-12 months was related (...) Effect of time to primary repair on final visual outcome after open globe injury. Historic data suggest that open globe injuries should be repaired within 12-24 hours to reduce the risk of endophthalmitis. However, endophthalmitis is uncommon when systemic antibiotic prophylaxis is given. It is not clear whether delayed primary repair impacts visual outcomes in other ways or what is the optimum time to repair. We aimed to examine the effect of time to primary repair on visual outcomes.This

2019 British Journal of Ophthalmology

165. Burning Eye Syndrome: Do Neuropathic Pain Mechanisms Underlie Chronic Dry Eye? (Full text)

Burning Eye Syndrome: Do Neuropathic Pain Mechanisms Underlie Chronic Dry Eye? Dry eye is a multi-factorial disorder that manifests with painful ocular symptoms and visual disturbances, which can only be partly attributed to tear dysfunction. This disorder may also involve neuroplasticity in response to neuronal injury. This review will emphasize the key characteristics of dry eye pain and its pathologic mechanisms, making the argument that a subset of dry eye represents a neuropathic pain (...) disorder of the eye, more appropriately called "burning eye syndrome."A literature review was conducted using a PubMed search focusing on dry eye, corneal nociception, and neuropathic pain. Articles were reviewed and those discussing clinical course, pathophysiology, and neuronal regulation of chronic ocular pain as related to dry eye were summarized.We found that there is a discordance between ocular pain and dryness on the ocular surface. Although tear dysfunction may be one of the initial insults

2015 Pain Medicine

166. Exercise-Based Knee and Anterior Cruciate Ligament Injury Prevention

pathology including damage to the joint (patellofemoral and/or tibiofemoral), ligaments, meniscus, or patellar tendon. Articles that focused on preventing knee injuries as a whole were included, but so too were articles focused on only one type of knee injury (eg, anterior cruciate ligament [ACL] injuries or patellofemoral pain). This CPG delineates between evidence related to ACL injuries and all knee injuries. Mechanism of injury included both contact (injuries as a result of collision with another (...) Exercise-Based Knee and Anterior Cruciate Ligament Injury Prevention Exercise-Based Knee and Anterior Cruciate Ligament Injury Prevention | Journal of Orthopaedic & Sports Physical Therapy ADVERTISEMENT Journal of Orthopaedic & Sports Physical Therapy | | | | | > > > Exercise-Based Knee and Anterior Cruciate Ligament Injury Prevention Clinical Practice Guidelines Exercise-Based Knee and Anterior Cruciate Ligament Injury Prevention Clinical Practice Guidelines Linked to the International

2018 The Orthopaedic Section of the American Physical Therapy Association (APTA), Inc.

167. Alcohol Related Harm

leading risk factor for premature death and disability in the world. It is estimated that 2.5 million people worldwide died from alcohol-related causes in 2004, including 320,000 young people between 15 and 29 years of age. 1 Alcohol misuse substantially contributes to social disruption, injury and death. In Australia about half the reported cases of interpersonal violence, domestic violence and sexual assault are related to excessive alcohol consumption. 2 Alcohol-fuelled incidents are also a factor (...) in up to two thirds of police callouts and around half of homicides. The College has developed its recommendations on reducing alcohol-related harm drawing on scientific evidence and the expertise of our Fellows in Australia and New Zealand, and other members of the medical profession. CONTEXT Surgeons are dramatically confronted with the effects of alcohol misuse when treating patients with injuries resulting from road traffic trauma, interpersonal violence and personal accidents that are related

2016 ASERNIP-S

168. Guidelines on post-exposure prophylaxis for HIV and the use of co-trimoxazole prophylaxis for HIV-related infections among adults, adolescents and children

Guidelines on post-exposure prophylaxis for HIV and the use of co-trimoxazole prophylaxis for HIV-related infections among adults, adolescents and children SUPPLEMENT GUIDELINES ON POST-EXPOSURE PROPHYLAXIS FOR HIV AND THE USE OF CO-TRIMOXAZOLE PROPHYLAXIS FOR HIV-RELATED INFECTIONS AMONG ADULTS, ADOLESCENTS AND CHILDREN: RECOMMENDATIONS FOR A PUBLIC HEALTH APPROACH DECEMBER 2014 SUPPLEMENT TO THE 2013 CONSOLIDATED GUIDELINES ON THE USE OF ANTIRETROVIRAL DRUGS FOR TREATING AND PREVENTING HIV (...) INFECTIONSUPPLEMENT GUIDELINES ON POST-EXPOSURE PROPHYLAXIS FOR HIV AND THE USE OF CO-TRIMOXAZOLE PROPHYLAXIS FOR HIV-RELATED INFECTIONS AMONG ADULTS, ADOLESCENTS AND CHILDREN: RECOMMENDATIONS FOR A PUBLIC HEALTH APPROACH DECEMBER 2014 SUPPLEMENT TO THE 2013 CONSOLIDATED GUIDELINES ON THE USE OF ANTIRETROVIRAL DRUGS FOR TREATING AND PREVENTING HIV INFECTIONWHO Library Cataloguing-in-Publication Data : Guidelines on post-exposure prophylaxis for HIV and the use of co-trimoxazole prophylaxis for HIV-related

2015 World Health Organisation HIV Guidelines

169. Corneal superficial injury

Hospital Discharge Survey for 2001 in the United States (n = 422,604 patient visits) found the incidence of superficial injury of the eye and adnexa to be approximately 3 per 1000 people and the incidence of foreign body on the external eye to be 2 per 1000 people [ ]. A study [ ] looking at work-related eye injuries in a large car manufacturing company in the United States over a 3 year period (n = 1,983) found that: Superficial corneal foreign body was the most common type of injury (69.2 (...) Corneal superficial injury Corneal superficial injury - NICE CKS Share Corneal superficial injury: Summary Superficial corneal injuries are non-penetrating injuries affecting the outermost layer of the cornea. Corneal abrasions are defects in the epithelial surface of the cornea — most heal in within 1–2 days. Superficial corneal injuries typically present with sudden onset pain, discomfort or foreign body sensation of the eye and tearing. The mechanism of injury and material involved should

2017 NICE Clinical Knowledge Summaries

170. Eye Examination

and pupil size ( , ) (including s) V. Exam: Comprehensive Eye Exam (Ophthalmology) Indications (see routine Eye Exam schedule above) Dilated Eye Exam with Tonometry Visual Field Testing VI. Exam: Tools ( ) Strongly consider use in acute presentations where is key (if not contraindicated) See l artery Tonometry (e.g. Tonopen or Applanation Tonometry) or other injury Foreign body Evaluate for Evaluate for VII. Exam: Eye Injury See See See Apply topical anesthesia (e.g. topical tetracaine) l (and lower (...) ) Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term "Eye Examination." Click on the image (or right click) to open the source website in a new browser window. Related Studies (from Trip Database) Ontology: Ophthalmic examination and evaluation (C0200149) Definition (NCI) A test performed by an ophthalmologist or optometrist assessing vision and ability to focus on and discern objects, as well as other tests and examinations pertaining

2018 FP Notebook

171. Eye Foreign Body

Body , Foreign Body Involving the Eye From Related Chapters II. Exam See Confirm that no has occurred Evert the s to check for a Use magnification (a small speck can cause significant pain) III. Prevention See Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term "Eye Foreign Body." Click on the image (or right click) to open the source website in a new browser window. Related Studies (from Trip Database) Related Topics in Traumatic (...) Eye Foreign Body Eye Foreign Body Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Eye Foreign Body Eye Foreign Body Aka: Eye Foreign

2018 FP Notebook

172. Blunt Eye Trauma

Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term "Blunt Eye Trauma." Click on the image (or right click) to open the source website in a new browser window. Related Studies (from Trip Database) Related Topics in Traumatic Injury About FPnotebook.com is a rapid access, point-of-care medical reference for primary care and emergency clinicians. Started in 1995, this collection now contains 6656 interlinked topic pages divided (...) Trauma From Related Chapters II. Exam Remove contacts immediately Removal difficult with swelling See III. Complications: Conditions secondary to blunt Trauma Penetrating with tic IV. Imaging: Indicated if penetrating injury suspected Orbital CT Scan (1-1.5 mm cuts, axial and coronal) or XRay (up and down gaze views) if CT not available V. Management Patients who are discharged Close interval follow-up Self-monitoring of vision and immediate return for worsening or lack of improvement VI. References

2018 FP Notebook

173. Acute Red Eye

, Eye Redness , Bloodshot Eye II. History Timing Acute, subacute or chronic Associated symptoms or Blurred Vision Photophobia Associated Conditions Systemic symptoms ( s or ) Recent illness or infection III. Exam: Eye (always) Consider first if light sensitive Delay only in cases of (irrigation precedes acuity exam) Visual fields by confrontation Defect suggests l, or CNS injury Free and painful movement in all directions exam Evaluate for pupil size and reactivity l Exam (typically with ) stain (...) abnormalities Narrow or shallow Blood ( ) Pus ( ) or external swelling or or Other Findings Irregularity in size and reactivity with Schiotz tonometer Omit for obvious infection Detect Limited s VII. References Williams (2017) Crit Dec Emerg Med 31(2): 3-12 Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term "Acute Red Eye." Click on the image (or right click) to open the source website in a new browser window. Related Studies (from Trip

2018 FP Notebook

174. Optical Coherence Tomography Monitoring Strategies for A-VEGF-Treated Age-Related Macular Degeneration

-related macular degeneration is an important retinal disease and is the leading cause of irreversible vision loss and blindness in older adults. The macula is the part of the retina that enables sharp central vision needed for close work, such as reading and writing, and for driving and recognizing faces. The estimated prevalence of any stage AMD is 6.5% and the prevalence of n-AMD increases from 0.04% in 50- year-olds to 2.79% in 80-year-olds to 10.49% (95% CI, 7.45% –14.37%) in 90-year-olds. Need (...) Optical Coherence Tomography Monitoring Strategies for A-VEGF-Treated Age-Related Macular Degeneration Optical Coherence Tomography Monitoring Strategies for A-VEGF–Treated Age-Related Macular Degeneration: OHTAC Recommendation. August 2014; pp. 1–13 Optical Coherence Tomography Monitoring Strategies for A-VEGF–Treated Age-Related Macular Degeneration: OHTAC Recommendation Ontario Health Technology Advisory Committee August 2014 Optical Coherence Tomography Monitoring Strategies for A-VEGF

2014 Health Quality Ontario

175. The RETINA Project: Reliable Eye Tracking in Neurocognitive Assessment of Traumatic Brain Injury

for study information Study Type : Observational Actual Enrollment : 183 participants Observational Model: Case-Control Time Perspective: Cross-Sectional Official Title: Eye Tracking Indicators of Neurocognitive Status After Traumatic Brain Injury Study Start Date : October 2010 Actual Primary Completion Date : August 2015 Actual Study Completion Date : October 2017 Resource links provided by the National Library of Medicine related topics: Groups and Cohorts Go to Group/Cohort TBI Group Adults (...) The RETINA Project: Reliable Eye Tracking in Neurocognitive Assessment of Traumatic Brain Injury The RETINA Project: Reliable Eye Tracking in Neurocognitive Assessment of Traumatic Brain Injury - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one

2012 Clinical Trials

176. Peri-operative Application of Eyeprotx General Anesthesia Goggles As Prevention Against Corneal Injury Post Intubation.

under general anesthesia. Condition or disease Intervention/treatment Phase Corneal Injuries Device: Eyeprotx™ General Anesthesia Protective Goggles Device: Eyelid Tape Device: Eye Ointment Not Applicable Detailed Description: Ocular injury is but a devastating condition that can occur perioperatively under general anesthesia. Corneal abrasion is the most common ocular injury during general anesthesia, surpassing case incidence of damage caused by patient movement in ophthalmologic surgery. Causes (...) of ocular injury include corneal drying due to the suppression of tear ducts from anesthetic agents, direct physical trauma, or agitation from the volatile anesthetic used. Ocular injury may also occur due to bacterial infection with MRSA, preventative methods, or rubbing of the eyes postoperatively due to agitation. Agitation may be caused by corneal drying or by shift or disruption in rapid eye movement sleep cycle from light penetration through the eyelids. Attempts at prevention of corneal abrasion

2018 Clinical Trials

177. Impaired healing of cornea incision injury in a TRPV1-deficient mouse (Full text)

incision injury (1.8 mm in length, limbus to limbus) in the central cornea of one eye with a surgical blade under general and topical anesthesia. The injury was not sutured. On days 0, 5, and 10, the eyes were enucleated, processed for histology, immunohistochemistry, and real-time RT-PCR gene expression analysis to evaluate the effects of the loss of TRPV1 on primary healing. Electron microscopy observation was also performed to know the effect of the loss of TRPV1 on ultrastructure of keratocytes (...) -related TRPV1 signal is involved in healing of stromal incision injury in a mouse cornea by selectively stimulating TGFβ-induced granulation tissue formation.

2018 Cell and tissue research

178. Imidazole Compounds for Protecting Choroidal Endothelial Cells from Complement Injury (Full text)

Imidazole Compounds for Protecting Choroidal Endothelial Cells from Complement Injury Age-related macular degeneration (AMD) is a common, blinding disease associated with increased complement system activity. Eyes with AMD show elevated accumulation of the membrane attack complex (MAC) in the choriocapillaris and degeneration of macular choriocapillaris endothelial cells (ECs). Thus, one could reasonably conclude that the endothelial cell death that occurs in AMD is due to injury by the MAC. We (...) therefore sought to identify strategies for protecting ECs against MAC lysis. RF/6A endothelial cells were pre-incubated with a library of FDA-approved small molecules, followed by incubation with complement intact human serum quantification of cell death. Two closely related molecules identified in the screen, econazole nitrate and miconazole nitrate, were followed in validation and mechanistic studies. Both compounds reduced lysis of choroidal ECs treated with complement-intact serum, across a range

2018 Scientific reports

179. Transcorneal Electrical Stimulation Inhibits Retinal Microglial Activation and Enhances Retinal Ganglion Cell Survival After Acute Ocular Hypertensive Injury (Full text)

Transcorneal Electrical Stimulation Inhibits Retinal Microglial Activation and Enhances Retinal Ganglion Cell Survival After Acute Ocular Hypertensive Injury To investigate the effect of transcorneal electrical stimulation (TcES) on retinal ganglion cell (RGC) function and survival after acute ocular hypertension-related retinal injury in gerbil eyes.Gerbil eyes were subjected to acute ocular hypertensive injury (80 mm Hg for 60 minutes). In the treatment group, TcES was applied to the surgical (...) eye immediately and then twice weekly for a total of 1 month. In the control group, sham TcES was given to the surgical eye at the same time points. Retinal function was assessed and compared between groups using flash electroretinography. For histological analysis, the number of RGC and microglial cells were counted by immunofluorescence staining after the gerbils were sacrificed on day 7 and day 28. Real-time polymerase chain reaction and western blot analysis were conducted to compare

2018 Translational vision science & technology

180. Vestibular Injury After Low-Intensity Blast Exposure (Full text)

Vestibular Injury After Low-Intensity Blast Exposure The increased use of close range explosives has led to a higher incidence of exposure to blast-related head trauma. Exposure to primary blast waves is a significant cause of morbidity and mortality. Active service members and civilians who have experienced blast waves report high rates of vestibular dysfunction, such as vertigo, oscillopsia, imbalance, and dizziness. Accumulating evidence suggests that exposure to blast-wave trauma produces (...) to 1 month after blast-wave exposure; damage that is likely permanent. Significant reductions in the ability to perform the righting reflex and balance on a rotating rod that lasted several weeks after blast exposure were prominent behavioral effects. We also observed a significant reduction in horizontal vestibuloocular reflex gain and phase lags in the eye movement responses that lasted many weeks following a single blast exposure event. OKN responses were absent immediately following blast

2018 Frontiers in neurology

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