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Work-Related Eye Injury

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141. Prevalence, subtypes, severity and determinants of ocular trauma: The Singapore Chinese Eye Study. (PubMed)

Prevalence, subtypes, severity and determinants of ocular trauma: The Singapore Chinese Eye Study. To describe the prevalence, subtypes, severity and determinants of ocular trauma (OT) in a population-based study in Singapore.We included 3353 Chinese adults aged ≥40 years from the Singapore Chinese Eye Study, a population-based study, conducted between 2009 and 2011. OT was defined as self-reported history of any eye injury requiring medical attention with or without hospitalisation (...) , and further classified as blunt object, sharp object or chemical burns related. Age and gender-standardised prevalence was estimated using the 2010 Singapore Chinese population census. Multivariable models were used to assess the independent associations of OT with age, gender, income, education, literacy, alcohol consumption, smoking and history of falls.The mean (SD) age was 59.7 (9.9) years and 49.4% were male. There were 138 OT cases, giving a crude and age and gender-standardised prevalence of 4.1

2017 British Journal of Ophthalmology

142. The connective tissue phenotype of glaucomatous cupping in the monkey eye - Clinical and research implications. (Full text)

The connective tissue phenotype of glaucomatous cupping in the monkey eye - Clinical and research implications. In a series of previous publications we have proposed a framework for conceptualizing the optic nerve head (ONH) as a biomechanical structure. That framework proposes important roles for intraocular pressure (IOP), IOP-related stress and strain, cerebrospinal fluid pressure (CSFp), systemic and ocular determinants of blood flow, inflammation, auto-immunity, genetics, and other non-IOP (...) related risk factors in the physiology of ONH aging and the pathophysiology of glaucomatous damage to the ONH. The present report summarizes 20 years of technique development and study results pertinent to the characterization of ONH connective tissue deformation and remodeling in the unilateral monkey experimental glaucoma (EG) model. In it we propose that the defining pathophysiology of a glaucomatous optic neuropathy involves deformation, remodeling, and mechanical failure of the ONH connective

2017 Progress in Retinal and Eye Research

143. Public data mining plus domestic experimental study defined involvement of the old-yet-uncharacterized gene matrix-remodeling associated 7 (MXRA7) in physiopathology of the eye.

Public data mining plus domestic experimental study defined involvement of the old-yet-uncharacterized gene matrix-remodeling associated 7 (MXRA7) in physiopathology of the eye. Matrix-remodeling associated 7 (MXRA7) gene was first reported in 2002 and named so for its co-expression with several genes known to relate with matrix-remodeling. However, not any studies had been intentionally performed to characterize this gene. We started defining the functions of MXRA7 by integrating (...) induced in Balb/c mice, and mRNA levels of Mxra7 as well as several matrix-remodeling related genes (Mmp3, Mmp13, Ecm1, Timp1) were monitored with RT-PCR. The results demonstrated a time-dependent Mxra7 under-expression pattern (U-shape curve along timeline), while all other matrix-remodeling related genes manifested an opposite changes pattern (dome-shape curve). When limited data from BioGPS concerning human MXRA7 gene expression in human tissues were looked at, it was found that ocular tissue

2017 Gene

144. Eye-Movement Desensitization and Post-Traumatic Syndroms

-Concussion Syndrome Trauma and Stressor Related Disorders Mental Disorders Brain Concussion Head Injuries, Closed Craniocerebral Trauma Trauma, Nervous System Nervous System Diseases Wounds and Injuries Wounds, Nonpenetrating (...) Eye-Movement Desensitization and Post-Traumatic Syndroms Eye-Movement Desensitization and Post-Traumatic Syndroms - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Eye-Movement Desensitization and Post

2017 Clinical Trials

145. Integrated Eye Tracking and Neural Monitoring for TBI: Optimization

] Spectral features and event related responses collected from scalp measurements during performance of an eye movement and working memory task. Eye Tracking [ Time Frame: One study visit ] Saccadic latencies measured in response to cognitive task including working memory demands. Secondary Outcome Measures : Neurobehavioral Symptom Inventory (NSI) [ Time Frame: One study visit ] Self-report measure of post-concussive symptoms Trail Making Test [ Time Frame: One study visit ] Consists of Part A and B (...) more than a few days post- injury. Therefore, development of advanced systems for assessment and diagnosis of TBI are a top priority within Department of Defense. This project aims to evaluate a combined electroencephalography (EEG) and eye tracking system capable of assessing compromised cognitive function stemming from TBI, with the goal of enhancing operational readiness and aiding in diagnosis, improving health care and rehabilitation for affected military personnel. Condition or disease

2017 Clinical Trials

146. Frequency Of Eye Problems In Type 2 Diabetes With Chronic Kidney Disease

Resource links provided by the National Library of Medicine related topics: related topics: Groups and Cohorts Go to Group/Cohort Intervention/treatment Group A 50 patients Type 2 Diabetes without renal impairment will be examined using fundoscope Device: fundoscope Fundoscope for eye examination Group B 25 patients Type 2 Diabetes with chronic kidney disease not on replacement therapy (stage I-IV) will be examined using fundoscope Device: fundoscope Fundoscope for eye examination Group C 25 patients (...) Haemodialysis unit in Luxor International Hospital. Criteria Inclusion Criteria: 50 patients Type 2 Diabetes without renal impairment. 25 patients Type 2 Diabetes with chronic kidney disease not on replacement therapy. (stage I-IV) 25 patients Type 2 Diabetes with end-stage renal disease on haemodialysis Exclusion Criteria: patients with previous history of eye problems and any systemic disease. Type 1 Diabetics . Acute kidney injury in Diabetics. Contacts and Locations Go to Information from the National

2017 Clinical Trials

147. Oxytocin Modulates Eye Gaze Behavior During Social Processing

Quotient (ASQ), Social Responsibilities Scale (SRS) and the Interpersonal Reactivity Index (IRI). Within-subject differences in the effects of oxytocin on social eye gazing behaviour will be related to individual differences in autistic traits. Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Estimated Enrollment : 40 participants Allocation: Randomized Intervention Model: Crossover Assignment Intervention Model Description: Randomized placebo (...) Oxytocin Modulates Eye Gaze Behavior During Social Processing Oxytocin Modulates Eye Gaze Behavior During Social Processing - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Oxytocin Modulates Eye Gaze

2017 Clinical Trials

148. Eye-Movement Desensitization and Reprocessing in the ED and Post-Traumatic Syndrome

-regulated Drug Product: No Studies a U.S. FDA-regulated Device Product: No Keywords provided by University Hospital, Bordeaux: Post-Traumatic Syndrome Eye-Movement Desensitization and Reprocessing Additional relevant MeSH terms: Layout table for MeSH terms Stress Disorders, Traumatic Stress Disorders, Post-Traumatic Trauma and Stressor Related Disorders Mental Disorders (...) Eye-Movement Desensitization and Reprocessing in the ED and Post-Traumatic Syndrome Eye-Movement Desensitization and Reprocessing in the ED and Post-Traumatic Syndrome - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before

2017 Clinical Trials

149. Detecting Malingering Detection Using Eye Movements and Response Time (MDER)

Assignment Masking: Single (Participant) Primary Purpose: Basic Science Official Title: Detecting Malingering Detection Using Eye Movements and Response Time Estimated Study Start Date : July 1, 2017 Estimated Primary Completion Date : January 1, 2019 Estimated Study Completion Date : January 1, 2019 Resource links provided by the National Library of Medicine related topics: Arms and Interventions Go to Arm Intervention/treatment Experimental: Sub-optimal Traumatic Brain Injury Sub-optimal effort (...) himself as having cognitive deficits or exaggerate existing cognitive deficits Other Name: Simulation condition Behavioral: optimal effort Participants will be asked to perform tasks to the best of their abilities. Other Name: control condition No Intervention: Traumatic Brain Injury optimal effort No Intervention: Chronic pain optimal effort Outcome Measures Go to Primary Outcome Measures : Eye Movements [ Time Frame: 1 month ] Eye tracking used to evaluate eye behavior. Eligibility Criteria Go

2017 Clinical Trials

150. Study on Prevention and Treatment of Dry Eye in Patients Using Glaucoma Drops

: May 3, 2018 See Sponsor: Shenzhen Hospital of Southern Medical University Information provided by (Responsible Party): Yingli Li, Shenzhen Hospital of Southern Medical University Study Details Study Description Go to Brief Summary: A multicenter randomized controlled trial on prevention and treatment of ocular surface injury and meibomian gland dysfunction in patients using anti-glaucoma eye drops. Condition or disease Intervention/treatment Phase Dry Eye MGD-Meibomian Gland Dysfunction Drug: 0.3 (...) and structural damage in the early stage of patients using anti glaucoma eye drops. Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Estimated Enrollment : 160 participants Allocation: Randomized Intervention Model: Parallel Assignment Masking: Single (Participant) Primary Purpose: Treatment Official Title: A Multicenter Randomized Controlled Trial on Prevention and Treatment of Ocular Surface Injury and Meibomian Gland Dysfunction in Patients Using Anti

2017 Clinical Trials

151. A Clinical Trial to Asses Efficacy and Safety of Cord Blood Eye Drops in Neurotrophic Keratopathy

A Clinical Trial to Asses Efficacy and Safety of Cord Blood Eye Drops in Neurotrophic Keratopathy A Clinical Trial to Asses Efficacy and Safety of Cord Blood Eye Drops in Neurotrophic Keratopathy - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove (...) one or more studies before adding more. A Clinical Trial to Asses Efficacy and Safety of Cord Blood Eye Drops in Neurotrophic Keratopathy The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03084861 Recruitment Status

2017 Clinical Trials

152. Walnut Shell Glasses Moxibustion for Dry Eye Syndrome

Completion Date : July 30, 2018 Estimated Study Completion Date : December 30, 2018 Resource links provided by the National Library of Medicine related topics: Arms and Interventions Go to Arm Intervention/treatment Experimental: Walnut Shell Glasses Moxibustion Use wire to make a glass frame which can fix two walnut shells and moxa roll in front of the eyes, the walnut shell should be soaked in medlar chrysanthemum water and use the moxibustion to treat eye disease. Procedure: Walnut Shell Glasses (...) , chemical injury patients. combined with cardiovascular and cerebrovascular, liver, kidney and hematopoietic system and other serious primary disease, mental patients. patients with Sjogren's syndrome. patients who are participating in other drug clinical trials. patients who are using other drugs or therapies for the treatment of dry eyes. Contacts and Locations Go to Information from the National Library of Medicine To learn more about this study, you or your doctor may contact the study research

2017 Clinical Trials

153. Legal and Ethical Issues related to Resuscitation

Legal and Ethical Issues related to Resuscitation ANZCOR Guideline 10.5 November 2015 Page 1 of 14 Section 10: Guideline 10.5 - Legal and Ethical Issues Related to Resuscitation Summary Note: This guideline does not constitute legal advice. Individuals and/or organizations should obtain legal advice if required for their own jurisdiction. Who does this guideline apply to? This guideline applies to adults, children and infant victims. Who is the audience for this guideline? This guideline (...) pertains to the important but limited number of legal and ethical issues concerning resuscitation encountered by first-aiders, first-responders and healthcare professionals. Some, but not all situations related to resuscitation are considered by Common and Statute law. Circumstances not considered by Statute law are subject to Common law. Index Page Duty to rescue 1 Consent for treatment 4 Treatment without consent 4 Advance care directives refusing treatment 9 Discontinuation (withdrawal

2015 Australian Resuscitation Council

154. Early Management of Head Injury in Adults

evidence becomes available. When it is due for updating, the Chairman of the CPG or National Advisor of the related specialty will be informed about it. A discussion will be done on the need for a revision including the scope of the revised CPG. A multidisciplinary team will be formed and the latest systematic review methodology used by MaHTAS will be employed. Early Management of Head Injury in Adults TABLE OF CONTENTS No. Title Page Levels of Evidence and Grades of Recommendation i Guidelines (...) of Abbreviation 62 Acknowledgement 63 Disclosure Statement 63 Source of Funding 63 No. Title PageEarly Management of Head Injury in Adults LEVELS OF EVIDENCE SOURCE: US / CANADIAN PREVENTIVE SERVICES TASK FORCE 2001 In line with the current development in CPG methodology, the CPG Unit of MaHTAS is in the process of adapting Grading Recommendations, Assessment, Development and Evaluation (GRADE) in its work process. The quality of each retrieved evidence and its effect size are carefully assessed/reviewed

2015 Ministry of Health, Malaysia

155. Management of Traumatic Brain Injury

earlier detection of changes. Assessment requires either a spontaneous response or response following application of a stimulus. At more severely disturbed levels of consciousness, the motor score has better discrimination, but in milder injuries the eye and verbal components are more relevant. Thus, each component of the scale (Eye, Verbal, Motor) provides complementary information. Strengths of the GCS are that it covers a broad spectrum of disorders of consciousness, is widely applicable (...) evidence of traumatic lesion on head CT, with 20% of those lesions requiring neurosurgical intervention. Therefore, the American College of Emergency Physicians recommends that a head CT be obtained in any patient age = 65 years who presents with mild head injury. There is a paucity of information related to acute management of intracranial hypertension resulting from TBI in the elderly. Age-related changes in intracranial space are known to lower ICP significantly, with a concomitant rise in CPP

2015 American College of Surgeons

156. ReWalk: Robotic Exoskeletons for Spinal Cord Injury

for people with paraplegia. While they provide users with mobility that allows them to perform many activities of daily living, wheelchairs are limited by numerous architectural and environmental barriers, their risk of causing shoulder and arm injuries, and the height restrictions for eye-to-eye interaction with non-SCI adults. More importantly, by not allowing the user to put weight on his or her legs, wheelchairs do not mitigate the adverse clinical conditions associated with SCI. 12 Mechanical (non (...) or recent (within the past two years) lower extremity fractures, psychopathology, or other cognitive issues were excluded. All but one study 15 also had similar exclusion criteria related to osteoporosis, severe spasticity, range of motion, and contractures. Participants who completed the studies (n = 35) were predominately male (83%) and ranged in age from 18 to 64 years. The time since injury ranged between one and 24 years. Regarding impairment, most participants had complete SCIs (91

2015 CADTH - Issues in Emerging Health Technologies

157. Observation is unnecessary following a normal CT brain in warfarinised head injuries: an update

of electronic records from 6 community hospital EDs, including 1 trauma centre over 2-year period. Only 38 patients had PT assessment (range 12–30.7 s) Cohort study Clinically significant intracranial injury No intracranial injury found in any of the 39 patients who had a CT. Telephone follow-up of the remaining 26 patients revealed no evidence of complications related to their head injuries Their computer system may not have identified all eligible patients leading to a selection bias. Retrospective (...) Observation is unnecessary following a normal CT brain in warfarinised head injuries: an update BestBets: Observation is unnecessary following a normal CT brain in warfarinised head injuries: an update Observation is unnecessary following a normal CT brain in warfarinised head injuries: an update Report By: Dr Simon Rendell, - Senior Emergency Trainee Search checked by Dr Laith Sultan, - Senior Emergency Trainee Institution: Manchester Royal Infirmary Date Submitted: 10th September 2013 Date

2014 BestBETS

158. Non-suicidal self-injury first aid guidelines

their self-injury, but avoid pressuring them to talk about it. Reflect what the person is saying by acknowledging their experience as they are describing it. Give support & reassurance Express empathy for how the person is feeling. Validate the person’s emotions by explaining that these emotions are appropriate and valid. Let them know they are not alone and that you are there to support them. Work 2.NON-SUICIDAL SELF-INJURY FIRST AID GUIDELINES (Revised 2014) 3. collaboratively with the person (...) Non-suicidal self-injury first aid guidelines NON-SUICIDAL SELF-INJURY FIRST AID GUIDELINES This document includes advice on assisting a person who is injuring themselves, but is not suicidal. It also includes advice on when you should seek professional medical help for a person who has severely injured themselves and is at risk of more serious harm or accidental death, regardless of intent. Remember that accidental death can occur. What is non-suicidal self-injury? The term non-suicidal self

2014 Clinical Practice Guidelines Portal

159. ReWalk: Robotic Exoskeletons for Spinal Cord Injury

for people with paraplegia. While they provide users with mobility that allows them to perform many activities of daily living, wheelchairs are limited by numerous architectural and environmental barriers, their risk of causing shoulder and arm injuries, and the height restrictions for eye-to-eye interaction with non-SCI adults. More importantly, by not allowing the user to put weight on his or her legs, wheelchairs do not mitigate the adverse clinical conditions associated with SCI. 12 Mechanical (non (...) or recent (within the past two years) lower extremity fractures, psychopathology, or other cognitive issues were excluded. All but one study 15 also had similar exclusion criteria related to osteoporosis, severe spasticity, range of motion, and contractures. Participants who completed the studies (n = 35) were predominately male (83%) and ranged in age from 18 to 64 years. The time since injury ranged between one and 24 years. Regarding impairment, most participants had complete SCIs (91

2015 CADTH - Issues in Emerging Health Technologies

160. Keeping an eye on pain: investigating visual attention biases in individuals with chronic pain using eye-tracking methodology (Full text)

to injury-related and neutral pictures. Individuals with (N=51) and without chronic pain (N=62) completed a dot-probe task using injury-related and neutral pictures while their eye movements were recorded. Mixed-design analysis of variance evaluated the interaction between group (chronic pain, pain-free) and picture type (injury-related, neutral). Reaction time results showed that regardless of chronic pain status, participants responded faster to trials with neutral stimuli in comparison to trials (...) that included injury-related pictures. Eye-tracking measures showed within-group differences whereby injury-related pictures received more frequent fixations and visits, as well as longer average visit durations. Between-group differences showed that individuals with chronic pain had fewer fixations and shorter average visit durations for all stimuli. An examination of how biases change over the time-course of stimulus presentation showed that during the late phase of attention, individuals with chronic

2016 Journal of pain research

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