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Work-Related Eye Injury

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181. Functional and Self-reported Outcomes in Participants With a History of Musculoskeletal Knee Injury

compared to the control group. In addition, the investigators hypothesize areas of educational and behavioral intervention related to PA engagement and dietary strategies to support weight management will be needed. Condition or disease Intervention/treatment Phase Anterior Cruciate Ligament Injury Anterior Cruciate Ligament Rupture Other: Exercise Group Not Applicable Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Estimated Enrollment : 26 (...) Functional and Self-reported Outcomes in Participants With a History of Musculoskeletal Knee Injury Functional and Self-reported Outcomes in Participants With a History of Musculoskeletal Knee Injury - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please

2018 Clinical Trials

182. Testing Mild Traumatic Brain Injury (mTBI) in Diverse Athletic Groups

: December 9, 2021 Estimated Study Completion Date : March 9, 2022 Resource links provided by the National Library of Medicine related topics: Arms and Interventions Go to Arm Intervention/treatment Experimental: Injured Athletes Athletes tested for mild traumatic brain injury (mTBI) after injury using the I-PAS goggles Device: I-PAS Goggles Portable, head-mounted display goggle system with integrated eye capture technology Active Comparator: Non-Injured Athletes Athletes tested for mild traumatic brain (...) injury (mTBI) with no injury using the I-PAS goggles Device: I-PAS Goggles Portable, head-mounted display goggle system with integrated eye capture technology Outcome Measures Go to Primary Outcome Measures : Number of participants with mTBI [ Time Frame: 45 months ] How many participants were detected to have mTBI following a sports-related injury Secondary Outcome Measures : Time to recover [ Time Frame: 45 months ] Measuring the time (days) it takes for readiness to return to sports activity after

2018 Clinical Trials

183. Disparity Driven Vergence in Mild Traumatic Brain Injury (mTBI)

by the National Library of Medicine related topics: Arms and Interventions Go to Arm Intervention/treatment Experimental: Injured Participants Participants with mild traumatic brain injury (mTBI) tested using the I-PAS goggles Device: I-PAS Goggles Portable, head-mounted display goggle system with integrated eye capture technology Active Comparator: Uninjured Participants Participants with no mild traumatic brain injury (mTBI) tested using the I-PAS goggles Device: I-PAS Goggles Portable, head-mounted display (...) Disparity Driven Vergence in Mild Traumatic Brain Injury (mTBI) Disparity Driven Vergence in Mild Traumatic Brain Injury (mTBI) - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Disparity Driven Vergence

2018 Clinical Trials

184. Rehabilitation of Social Cognition in Subjects With Traumatic Brain Injury

in Subjects With Traumatic Brain Injury. Efficiency of a Computer Rehabilitation Treatment Actual Study Start Date : January 2, 2018 Estimated Primary Completion Date : January 2, 2021 Estimated Study Completion Date : January 2, 2022 Resource links provided by the National Library of Medicine related topics: Arms and Interventions Go to Arm Intervention/treatment Experimental: GNPT + Social Cognition Experimental Group: will undertake a rehabilitation treatment integrated by a set of tasks aimed (...) Rehabilitation of Social Cognition in Subjects With Traumatic Brain Injury Rehabilitation of Social Cognition in Subjects With Traumatic Brain Injury - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more

2018 Clinical Trials

185. Muscle Function and Traumatic Knee Injury in Sports

(soccer, handball, floorball and basket). The study started autumn 2017 with assessment of muscle function at baseline, instructed and supervised by two test leaders. Before the test session the athlete will be informed and tutored about the injury and exposure registration procedure. Measurements takes place in a secluded room at the athletes' school and will be carried out during the first semester (autumn 2017 and 2018). Data relating to sport affiliation, number of years of specific sport training (...) Resource links provided by the National Library of Medicine related topics: (AHRQ) related information: Groups and Cohorts Go to Group/Cohort Youth female athletes with poor muscle function Youth female athletes with good muscle function Outcome Measures Go to Primary Outcome Measures : Traumatic knee injury assessed by a web-designed (REDCap Software) registration form [ Time Frame: 2 years ] Muscle strength will be assessed using an isometric handheld dynamometer (Commander Echo, JTECH Medical, Salt

2018 Clinical Trials

186. Thromboelastometry-identified Haemostatic Changes in Isolated Traumatic Brain Injury

of Intracranial Injury and Clinical Outcome in Patients With Isolated Traumatic Brain Injury Actual Study Start Date : August 21, 2018 Estimated Primary Completion Date : August 30, 2020 Estimated Study Completion Date : December 31, 2020 Resource links provided by the National Library of Medicine related topics: Arms and Interventions Go to Arm Intervention/treatment No Intervention: Conventional therapy Intraoperative haemostatic treatment is based on conventional coagulation assays. Active Comparator: Goal (...) the level of consciousness after neurological injury according to best eye (range 1 to 4), verbal (range 1 to 5) and motor (range 1 to 6) response of the patient. Eye, verbal and motor scores are summed to give the total Glasgow coma score (range 3 to 15). The lowest possible GCS (the sum) is 3 (deep coma or death), while the highest is 15 (fully awake person). Secondary Outcome Measures : Coagulation abnormalities on conventional coagulation assays and ROTEM [ Time Frame: 72 hours ] The number

2018 Clinical Trials

187. Hyperpolarized Noble Gas MRI Detection of Radiation-Induced Lung Injury

, injury to the lungs is moderate to severe (2). In addition, radiation-induced pneumonitis that produces symptoms occurs in 5-50% of individuals given radiotherapy for lung cancer (3, 4). The chances of clinical radiation pneumonitis are directly related to the irradiated volume of lung (5). However, radiation planning currently assumes that all parts of the lung are equally functional. Identification of the areas of the lung that are more functional would be beneficial in order to prioritize those (...) Hyperpolarized Noble Gas MRI Detection of Radiation-Induced Lung Injury Hyperpolarized Noble Gas MRI Detection of Radiation-Induced Lung Injury - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Hyperpolarized

2018 Clinical Trials

188. The ten-year experience of firework injuries treated at a uk regional burns & plastic surgery unit (PubMed)

The ten-year experience of firework injuries treated at a uk regional burns & plastic surgery unit Fireworks are used worldwide to celebrate national, religious, cultural festivals and holidays. However the use of fireworks is associated with preventable injuries. We aim to review cases of burns and trauma caused by fireworks presenting to a regional burns and plastic surgery unit in the United Kingdom. We hope our findings will help to guide future firework-related safety practices in the UK (...) in October and November. Mechanism of injury included contact, flash, flame burns and injury secondary to blast force. Most injuries sustained were to the hands, followed by head and neck, torso, limbs and perineum in descending order of frequency. A total of 38.7% of patients required surgery for their wounds. Fireworks not only result in significant burn injuries, but also eye injuries, soft tissue defects and fractures requiring a spectrum of plastic surgical interventions. The number and severity

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2018 Annals of burns and fire disasters

189. Visual outcomes and prognostic factors in open-globe injuries. (PubMed)

Trauma Classification Group, wound location was classified into three zones. Chi-square test was used to compare presented data.Out of the 59 patients, 46 were placed in the Light Perception (LP) group, and 13 were placed in the No Light Perception (NLP) group. Work-related trauma was the most common cause (27 eyes) followed by falls (19eyes). Work-related trauma was common in males (P = 0.004), while falls was significantly common in females (P = 0.00001). Zone III injuries had statistically (...) Visual outcomes and prognostic factors in open-globe injuries. Ocular trauma is an important cause of visual loss worldwide. Improvements in our knowledge of the pathophysiology and management of ocular trauma during the past 30 years, in conjunction with advances in the instrumentation and techniques of ocular surgery, have improved the efficacy of vitreoretinal surgery in injured eyes. The aim of the current study was to determine the visual outcomes and prognostic factors of open-globe

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2018 BMC Ophthalmology

190. Trends in US Emergency Department Visits for Pediatric Acute Ocular Injury. (PubMed)

Trends in US Emergency Department Visits for Pediatric Acute Ocular Injury. There is a lack of literature describing the incidence of pediatric acute ocular injury and associated likelihood of vision loss in the United States. Understanding national pediatric eye injury trends may inform future efforts to prevent ocular trauma.To characterize pediatric acute ocular injury in the United States using data from a stratified, national sample of emergency department (ED) visits.A retrospective (...) a strike to the eye (22.5%; 95% CI, 21.3-23.8) and affected the adnexa (43.7%; 95% CI, 42.7-44.8). Most injuries had a low risk for vision loss (84.2%; 95% CI, 83.5-85.0), with only 1.3% (95% CI, 1.1-1.5) of injuries being high risk. Between 2006 and 2014, pediatric acute ocular injuries decreased by 26.1% (95% CI, -27.0 to -25.0). This decline existed across all patient demographic characteristics, injury patterns, and vision loss categories and for most mechanisms of injury. There were increases

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2018 JAMA ophthalmology

191. An Acute Injury Model for the Phenotypic Characteristics of Geographic Atrophy. (PubMed)

An Acute Injury Model for the Phenotypic Characteristics of Geographic Atrophy. Geographic atrophy (GA) is the late stage of non-neovascular age-related macular degeneration. A lack of animal models for GA has hampered treatment efforts. Presented herein is a rat model for GA using subretinal injection of sodium iodate (NaIO3).Rats were given subretinal injections of NaIO3 (5 μg/μL) using a pico-injector. Fundus photographs and spectral domain optical coherent tomography scans were collected (...) at 1, 3, 7, 14, and 28 days after injection, at which time rats were euthanized and eyes were enucleated. Eyes were either cryopreserved or dissected into retinal and choroidal flatmounts. Fluorescence immunohistochemistry was performed for retinal glial fibrillary acidic protein (activated Müller cells and astrocytes) and vimentin (Müller cells), as well as peanut agglutin lectin (photoreceptors) labeling. RPE/choroids were labeled for RPE65 and CD34. Images were collected on Zeiss confocal

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2018 Investigative Ophthalmology & Visual Science

192. Mitochondria-targeted antioxidant SKQ1 protects cornea from oxidative damage induced by ultraviolet irradiation and mechanical injury. (PubMed)

Mitochondria-targeted antioxidant SKQ1 protects cornea from oxidative damage induced by ultraviolet irradiation and mechanical injury. Cornea protects the eye against natural and anthropogenic ultraviolet (UV) damage and mechanical injury. Corneal incisions produced by UV lasers in ophthalmic surgeries are often complicated by oxidative stress and inflammation, which delay wound healing and result in vision deterioration. This study trialed a novel approach to prevention and treatment (...) of iatrogenic corneal injuries using SkQ1, a mitochondria-targeted antioxidant approved for therapy of polyethiological dry eye disease.Rabbit models of UV-induced and mechanical corneal damage were employed. The animals were premedicated or treated with conjunctival instillations of 7.5 μM SkQ1. Corneal damage was assessed by fluorescein staining and histological analysis. Oxidative stress in cornea was monitored by measuring malondialdehyde (MDA) using thiobarbituric acid assay. Total antioxidant activity

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2018 BMC Ophthalmology

193. A 3-year prospective study on ocular injuries with tennis or cricket ball while playing cricket: A case series (PubMed)

A 3-year prospective study on ocular injuries with tennis or cricket ball while playing cricket: A case series The purpose of this study is to study the clinical features, visual outcome, management, and ocular complications of ocular injury, following trauma with tennis or cricket ball.A prospective, noncomparative case study of patients having injury with tennis/cricket ball while playing cricket was conducted between January 2013 and April 2016. Seventy-six eyes of 76 patients were studied (...) . Presenting vision, age, gender, time since injury, general and ocular examination, intraocular pressure, indirect ophthalmoscopy, B scan, and X-ray/computed tomography scan findings were noted. Patients were managed medically or surgically as per the need and followed up at least for 6 months.Seventy-six eyes of 76 patients were studied. All cases were male, except two. Majority (80.2%) were <25 years. Median presenting visual acuity (VA) was 6/36 and median final VA was 6/18. Significant findings

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2018 Indian journal of ophthalmology

194. Red eye

Red eye Red eye - NICE CKS Share Red eye: Summary There is a wide differential diagnosis for red eye. It is important to differentiate whether the person presenting with red eye needs same day assessment by an ophthalmologist, or if they can be safely managed in primary care. Serious and potentially sight-threatening causes of red eye include: Acute glaucoma. Corneal ulcer, contact lens-related red eye and corneal foreign body. Anterior uveitis. Scleritis. Trauma, such as penetrating eye injury (...) of the eyelid margin). Entropion (inward rotation of the eyelid margin). Trichiasis (misdirection of the eyelashes towards the cornea). Child maltreatment. Although rare, suspect this if a child has retinal haemorrhages, or injury to the eye in the absence of major confirmed accidental trauma, or a known medical explanation, including birth-related causes [ ]. For more information, see the CKS topic on . Serious and potentially sight-threatening causes of red eye include: Acute glaucoma. This occurs when

2016 NICE Clinical Knowledge Summaries

195. Patterns of Pediatric Firearm-Related Ocular Trauma in the United States. (PubMed)

Patterns of Pediatric Firearm-Related Ocular Trauma in the United States. Gun violence represents a substantial public health issue, and firearm-related injuries rank second among the causes of injury-related deaths in children aged 0 to 17 years in the United States. Ocular trauma from firearm-related injuries can lead to devastating vision loss, but little is known to date about the specific demographics and characteristics of such injuries in children.To evaluate the epidemiologic pattern (...) of pediatric firearm-related ocular injuries.This retrospective analysis used deidentified data from the National Trauma Data Bank, the largest national registry of hospitalized trauma cases in the United States. The firearm-related ocular injuries (n = 1972) of pediatric patients (defined as those younger than 21 years) hospitalized between January 1, 2008, and December 31, 2014, were analyzed. Statistical analyses were conducted from July 15, 2017, to June 15, 2019.Firearm-related ocular trauma.Pediatric

2019 JAMA ophthalmology

196. Diagnosis and Management of Idiosyncratic Drug-Induced Liver Injury

lleg e o f Gastr o en t e r o log y Idiosyncratic drug-induced liver injury (DILI) is a rare adverse drug reaction and it can lead to jaundice, liver failure, or even death. Antimicrobials and herbal and dietary supplements are among the most common therapeutic classes to cause DILI in the Western world. DILI is a diagnosis of exclusion and thus careful history taking and thorough work-up for competing etiologies are essential for its timely diagnosis. In this ACG Clinical Guideline, the authors (...) Diagnosis and Management of Idiosyncratic Drug-Induced Liver Injury nature publishing group 1 © 2014 by the American College of Gastroenterology The American Journal of GASTROENTEROLOGY PRACTICE GUIDELINES PREAMBLE The writing group was invited by the Board of the Trustees and the Practice Parameters Committee of the American College of Gastroenterology to develop a practice guideline regarding the diagnosis and management of idiosyncratic drug-induced liver injury (DILI). The writing group

2014 American College of Gastroenterology

197. Management of Anterior Cruciate Ligament Injuries

Management of Anterior Cruciate Ligament Injuries i MANAGEMENT OF ANTERIOR CRUCIATE LIGAMENT INJURIES EVIDENCE- BASED CLINICAL PRACTICE GUIDELINE Adopted by the American Academy of Orthopaedic Surgeons Board of Directors September 5, 2014 This Guideline has been endorsed by the following organizations: ii Disclaimer This Clinical Practice Guideline was developed by an AAOS multidisciplinary volunteer Work Group based on a systematic review of the current scientific and clinical information (...) diagnostic tools for ACL injury. Strength of Recommendation: Strong Description: Evidence from two or more “High” strength studies with consistent findings for recommending for or against the intervention. ACL RADIOGRAPHS In the absence of reliable evidence, it is the opinion of the work group that in the initial evaluation of a person with a knee injury and associated symptoms [giving way, pain, locking, catching] and signs [effusion, inability to bear weight, bone tenderness, loss of motion

2014 American Academy of Orthopaedic Surgeons

198. Observation is unnecessary following a normal CT brain in warfarinised head injuries: an update

of electronic records from 6 community hospital EDs, including 1 trauma centre over 2-year period. Only 38 patients had PT assessment (range 12–30.7 s) Cohort study Clinically significant intracranial injury No intracranial injury found in any of the 39 patients who had a CT. Telephone follow-up of the remaining 26 patients revealed no evidence of complications related to their head injuries Their computer system may not have identified all eligible patients leading to a selection bias. Retrospective (...) Observation is unnecessary following a normal CT brain in warfarinised head injuries: an update BestBets: Observation is unnecessary following a normal CT brain in warfarinised head injuries: an update Observation is unnecessary following a normal CT brain in warfarinised head injuries: an update Report By: Dr Simon Rendell, - Senior Emergency Trainee Search checked by Dr Laith Sultan, - Senior Emergency Trainee Institution: Manchester Royal Infirmary Date Submitted: 10th September 2013 Date

2014 BestBETS

199. Age-Related Macular Degeneration

Ophthalmologist, Newcastle Royal Infirmary. College Scientific Advisor Mr John Sparrow- Consultant Ophthalmologist, Bristol Royal Infirmary. 7 Vision Scientists Professor Gary Rubin - Helen Keller Professor of Ophthalmology UCL Institute of Ophthalmology, London. Ms Jennifer Evans – Epidemiologist and Cochrane Eyes and Vision Group Editor, Lecturer, International Centre for Eye Health, London School of Hygiene and Tropical Medicine. Patient Representative Ms Cathy Yelf – Head of External Relations, Macular (...) ). The Age Related Eye 12 Disease Study (AREDS) is an ongoing randomised controlled clinical trial of dietary supplements in some 4000 participants ranging from persons with no evidence of early or late AMD in either eye to those with late AMD in one eye (9) (see also sections 6.1.4 and 6.2.3). Participants were randomly assigned to receive daily oral tablets containing: (1) antioxidants (vitamin C, 500 mg; vitamin E, 400 IU; and beta carotene, 15 mg); (2) zinc, 80 mg, as zinc oxide and copper, 2 mg

2013 Royal College of Ophthalmologists

200. 5 reasons to keep working after financial independence

5 reasons to keep working after financial independence 5 reasons to keep working after financial independence 5 reasons to keep working after financial independence | | January 16, 2018 65 Shares I was browsing the Bogleheads forum last night, and my eyes naturally gravitated to the thread titled “ ” The short answer is that FI is financial independence. Nothing more, nothing less, and it doesn’t look any different if you love, hate, or feel indifferent towards your job. The long answer, after (...) learning that the man asking the question is about ten years away from FI, includes the fact that the person or the job is quite likely to look and feel quite a bit different in 10 years, and Fi is a smart play for anyone. Quite a few nuggets of wisdom were dropped in the replies, and I added my two cents, as well. I think everyone should try to work towards financial independence, regardless of their current contentedness. The flip side of that question is what do you do when you reach FI and still

2018 KevinMD blog

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