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Wechsler Intelligence Scale

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161. Executive Functions Rehabilitation in Premature Children

(a psychologist expert in premature children). A control group of 35 children (no training) with the same characteristics (gestational age, cognitive profile, socio-economic status) will be available. Before and after the training/or no training the participants, in addition to the scheduled follow-up assessment, will be evaluated with two WPPSI-III®-Wechsler Preschool and Primary Scale of Intelligence subtests (Coding and Symbol search) and one Nepsy II® domain-A developmental Neuropsychological Assessment (...) Cognitive Video Games Software No Intervention: no training children not submitted to the training, entering the study as a control group Outcome Measures Go to Primary Outcome Measures : change in WPPSI-III ( Wechsler Preschool and Primary Scale of Intelligence) Processing Speed Quotient [ Time Frame: assessment at baseline (time 0) and at the end of the training (after 4 weeks) ] the achievement of at least 10 points change of WPPSI® Processing Speed Quotient (subtests: Coding and Symbol search

2018 Clinical Trials

162. Family-Centered Intervention for Preterm Children: Effects at School Age and Biosocial Mediators

, teaching of child developmental skills, feeding support, teaching of interactional activities, and parent support and education. Other Name: early intervention program Outcome Measures Go to Primary Outcome Measures : Child: Neurodevelopment- The Wechsler Preschool and Primary Scale of Intelligence-Fourth Edition [ Time Frame: 2 years ] The Wechsler Preschool and Primary Scale of Intelligence-Fourth Edition (WPPSIR-IV) measures cognitive development of children aged from 6 years to 16 years and 11 (...) months old. The test structure of WPPSIR-IV includes 14 subscales and several levels of interpretation: verbal comprehension index, perceptual reasoning index, working memory index, processing speed index and full scale intelligence quotient. The scaled score of each subscale ranges from 1 to 19. The total scaled score is the sum of the subscale scores ranging from 10 to 190. The full scale intelligence quotient will be converted from the total scaled score with a higher value indicating a better

2018 Clinical Trials

163. Preterm Birth Cohort Study in Guangzhou

to Primary Outcome Measures : Neurodevelopment at early childhood [ Time Frame: At age of 1 year ] Assessed by using the Gesell Developmental Schedules, which include adaptive, gross motor, fine motor, language, and social function domains. Higher score in each domain is considered a better outcome, while no more than 85 is defined as suspected development retardation Secondary Outcome Measures : Intelligence quotient of offspring [ Time Frame: At age of 6 years old ] Assessed by using Wechsler's (...) Intelligence Scale for Children (WISC), which can generate a full scale intelligence quotient score and five primary index scores including verbal comprehension, visual spatial, fluid reasoning, working memory, and processing speed. Intelligence quotient ranges from 40 to 160,in which less than 70 is defined as mental retardation Height changes during childhood and adolescence [ Time Frame: At birth, age of 6 weeks, 6 months, 1 year, 3 years, 6 years, 12 years and 18 year ] Measured by nurses in clinic

2018 Clinical Trials

164. Feasibility and Acceptability of a Physical Activity Behavior Change Intervention for Parkinson's Disease

back to chair. Time to complete is recorded Change from Baseline 6 minute walk test at 4 months [ Time Frame: baseline and 4 months ] Assesses the distance walked over 6 minutes as a sub-maximal test of aerobic capacity/endurance. Change from Baseline Brunel Lifestyle Inventory at 4 months [ Time Frame: baseline and 4 months ] The Brunel lifestyle inventory is a 10-item questionnaire that measures both pre-planned and un-planned lifestyle PA Change from Baseline Wechsler Adult Intelligence Scale (...) by 4 questions, except for introjected regulation which has 3. Questions are scored using a 5-point Likert scale; Answers range from 0 (not true for me) to 4 (very true for me). Subscale scores (sum totals of the 3 or 4 questions) will be reported and compared across participants. Subscales have a maximum score of 16 (12 for introjected regulation) and a minimum score of 0. An overall score (RAI-score, Relative Autonomy Index) for motivation quality will also be constructed. This is done

2018 Clinical Trials

165. Clinical Trial of The Boosting Effect of Transcranial Random Noise Stimulation (tRNS) in Cognitive Rehabilitation of Patients With Traumatic Brain Injury

from the Wechsler Adult Intelligence Scale [ Time Frame: 1 day ] To improve performance in span of immediate verbal recall after receiving experimental intervention. Digit Span Backward from the Wechsler Adult Intelligence Scale [ Time Frame: 1 day ] To improve performance in working memory after receiving experimental intervention. Rey Auditory Verbal Learning Test [ Time Frame: 1 day ] To improve performance in short-term, long-term and recognition. Letters and Numbers from the Wechsler Adult (...) Intelligence Scale [ Time Frame: 1 day ] To improve performance in working memory after receiving experimental intervention. Spanish phonemic fluency test (PMR) [ Time Frame: 1 day ] To improve performance in phonemic fluency after receiving experimental intervention. Secondary Outcome Measures : Trail Making Test A (TMT-A) [ Time Frame: 1 day ] To improve performance in visual attention Trail Making Test B (TMT-B) [ Time Frame: 1 day ] To improve performance in task-switching Wisconsin Card Sorting Test

2018 Clinical Trials

166. Assessment and Treatment of Cognitive Functioning Deficits in Veterans With PTSD

. Total score ranges from 0-80. Higher scores represent better outcomes. Wechsler Adult Intelligence Scale (WAIS-IV) Digit Span & Coding subtests (Wechsler, 2008) [ Time Frame: change from baseline to 3 and 6 months ] attention, working memory, processing speed, reliable digit span validity. Higher scores represent better outcomes. Scores on each subtest range from 0-18 and are reported as WAIS Scaled Scores. Controlled Oral Word Association Test (Benton, Hamsher, & Sivan, 1983) [ Time Frame: change (...) cognitive rehabilitation intervention for Veterans with a history of brain injury, but VA clinicians need data on its effectiveness for Veterans with PTSD-related cognitive functioning deficits. These studies will provide the data necessary for a larger scale RCT proposal if results show that CCT is as promising as expected for Veterans with PTSD. Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Estimated Enrollment : 36 participants Allocation

2018 Clinical Trials

167. IVF Offspring Born in Guangzhou

: At age of 6 years old ] Assessed using Wechsler's Intelligence Scale of Children (WISC) including verbal test and performance test.Intelligence quotient ranges from 40 to 160, in which under 70 is defined as mental retardation Secondary Outcome Measures : Prevalence of gestational diabetes, pregnancy induced hypertension, and cesarean section [ Time Frame: From 20 weeks of gestation to delivery ] Assessed by self-reported time of onset and electronic medical records Prevalence of stillbirth, preterm (...) Go to Layout table for study information Study Type : Observational Estimated Enrollment : 3000 participants Observational Model: Cohort Time Perspective: Prospective Official Title: IVF Offspring Born in Guangzhou Cohort Study Actual Study Start Date : February 1, 2012 Estimated Primary Completion Date : December 31, 2019 Estimated Study Completion Date : December 31, 2038 Groups and Cohorts Go to Outcome Measures Go to Primary Outcome Measures : Intelligence quotient of offspring [ Time Frame

2018 Clinical Trials

168. Cross-sex Hormone Therapy and Neuronal Plasticity

magnetic resonance imaging Glutamate concentration in the anterior cingulate cortex and left dorsolateral prefrontal cortex [ Time Frame: 90 days ] Proton spectroscopy - magnetic resonance imaging; Glutamate concentration in the left dorsolateral prefrontal cortex will be correlated to over all measures of cognition and executive functioning. Cognition [ Time Frame: 90 days ] Instrument: Wechsler Adult Intelligence Scale (WAIS) version 3. Subscale: Full Scale Intelligence coefficient. Mean: 100 (...) Standard deviation (SD):15 for Brazilian population. Range of classification: 69 and below - Extremely Low 70-79 - Borderline 80-89 - Low Average 90-109 - Average 110-119 - High Average 120-129 - Superior 130 and above - very superior Operational memory [ Time Frame: 90 days ] Subscale from Wechsler Adult Intelligence Scale (WAIS) version 3. Mean: 100 Standard deviation (SD):15 for Brazilian population. 69 and below - Extremely Low 70-79 - Borderline 80-89 - Low Average 90-109 - Average 110-119 - High

2018 Clinical Trials

169. Efficacy Study of Deep Brain Stimulation in Patients With Treatment Resistant Major Depression

Assessments: Wechsler Adult Intelligence Scale (WAIS) (vocabulary, similarities) [ Time Frame: at 6 months DBS compared to baseline and at end of the study compared to baseline, assessed up to 77 weeks ] see above Neuropsychological Assessments: Mini-Mental-Status-Test (MMST) [ Time Frame: at 6 months DBS compared to baseline and at end of the study compared to baseline, assessed up to 77 weeks ] see above Neuropsychological Assessments: Multiple-Choice Vocabulary Intelligence Test (MWT-B) [ Time Frame (...) Intelligence Scale (WAIS) (vocabulary, similarities) [ Time Frame: at 4 months after implantation ] Score range "vocabulary": 0-32, Score range "finding similarities": 0-32, higher scores indicate better cognitive performance Neuropsychological Assessments: Mini-Mental-Status-Test (MMST) [ Time Frame: at 4 months after implantation ] Score range 0-30, higher scores indicate better cognitive performance Neuropsychological Assessments: Multiple-Choice Vocabulary Intelligence Test (MWT-B) [ Time Frame: at 4

2018 Clinical Trials

170. Acute Effects of Exercise in College Students With ADHD

at each experimental appointment over a period of two weeks ] The Digit Span (Wechsler, 2008) subtest of the Wechsler Adult Intelligence Scale (WAIS-IV) is an auditory working memory task. The researcher will say numbers aloud at a rate of one number per second. The participant will be tasked with remembering and repeating the numbers in a prescribed (forward, backward, sequencing) order. Participants will complete the Digit Span (forward, backward and sequencing) auditory working memory task at each (...) experimental appointment. For the SIT appointment, participants will complete the Digit Span (forward, backward and sequencing) tasks approximately 15 minutes after exercise termination. Change in Letter-Number Sequencing from appointment 1 to 2 [ Time Frame: Completed at each experimental appointment over a period of two weeks ] The Letter-Number Sequencing (Wechsler, 2008) task is a supplemental subtest of the Wechsler Adult Intelligence Scale (WAIS-IV) that measures auditory working memory. Researchers

2018 Clinical Trials

171. Mindfulness-Based Stress Reduction (MBSR) and Transcranial Direct Current Stimulation (tDCS)

software, participation in psychotherapy or regular engagement in mindfulness practice and/or yoga. Taking anticonvulsant or antipsychotics that cannot be safely tapered and discontinued. Significant neurological condition (e.g. stroke, seizure disorder, multiple sclerosis). A pace-maker or other metal implants that would preclude safe use of tDCS. Intelligence Quotient (IQ) < 70 as estimated by the Wechsler Test of Adult Reading. Contacts and Locations Go to Information from the National Library (...) : Baseline, Approximately 10-14 weeks after baseline ] Change in anxiety symptoms as assessed by Patient-Reported Outcomes Measurement Information System (PROMIS) anxiety symptoms [ Time Frame: Baseline, Approximately 10-14 weeks after baseline ] Change in quality of life as assessed by PROMIS Scale for Ability to Participate in Social Roles and Activities, the PROMIS Scale for Satisfaction with Social Roles and Activities and the [ Time Frame: Baseline, Approximately 10-14 weeks after baseline ] Change

2018 Clinical Trials

172. The Effect of tDCS on Schizophrenia With Negative Symptoms

fNIRS [ Time Frame: approximately 2 weeks (baseline and 2 weeks followups) ] change in level of the Oxy-Hemoglobin Korean Wechsler Adult Intelligence Scale (K-WAIS) [ Time Frame: baseline ] baseline total Intelligence quotient value Spatial Working Memory [ Time Frame: approximately 2 weeks (baseline and 2 weeks followups) ] changes in the spatial working memory ability California Verbal Learning Test [ Time Frame: approximately 2 weeks (baseline and 2 weeks followups) ] changes in verbal learning (...) sessions per day with at least 3hours interval between sessions, a total of 10 tDCS sessions Device: tDCS Transcranial direct current stimulation (tDCS) is a form of neurostimulation that uses constant, low direct current delivered via electrodes on the head. It can be contrasted with cranial electrotherapy stimulation, which generally uses alternating current the same way Outcome Measures Go to Primary Outcome Measures : Positive and Negative Syndrome Scale (PANSS) [ Time Frame: approximately 2 weeks

2018 Clinical Trials

173. Probiotics to Treat "Inflammatory Depression"

6 different domains, ranging from 0-144. Generalized Anxiety Disorder-7 (GAD-7) [ Time Frame: 8 weeks ] Total Composite score of 7 items, measuring anxiety symtoms, ranging from 0-21. Insomnia Severity Index (ISI) [ Time Frame: 8 weeks ] Total Composite score of 7 items, ranging from 0-28 Fatigue Severity Scale (FSS) [ Time Frame: 8 weeks ] Total Composite score of 9 items, measuring severity of fatigue, ranging from 1-63 Wechsler Adult Intelligence Scale (WAIS-IV) [ Time Frame: 8 weeks ] Two (...) Intervention Model: Parallel Assignment Intervention Model Description: Intervention will be add-on specific probiotic to ongoing treatment with antidepressant medication or Cognitive Behavioral Therapy (CBT). Subjects will be randomized to placebo or probiotic. To assure a balanced subject recruitment, block randomization within strata (ongoing treatment with CBT, antidepressant or both) will be performed. Blood sampling and symptom rating scales will be completed at baseline, at weeks 4 and 8 (end

2018 Clinical Trials

174. Heated Vest for Persons With Spinal Cord Injury

with tetraplegia only (Visits 2 & 3). Testing conditions will be identical, quiet, and distraction-free. Wechsler Adult Intelligence Scale-Fourth Edition (WAIS-IV): Subjects will be asked to repeat 2-9 numbers forward, backward and in ascending order to assess attention, processing speed, and working memory. Each assessment requires 10 min. Change in Cognitive Performance: Delayed Recall [ Time Frame: Visits 2 & 3 (subjects with tetraplegia only): At the end baseline (at 15 min) & end of Thermal Challenge (...) of the instructions. Each assessment requires 4 min. Secondary Outcome Measures : Change in Thermal Comfort (TC) [ Time Frame: Visits 1, 2, & 3 (all subjects): During baseline & every 10 minutes throughout Thermal Challenge (2 hrs). The change in TC from baseline to the end of Thermal Challenge will be determined. ] Thermal Comfort will be measured every 10 minutes throughout BL and thermal challenge periods by the Zhang 6-point thermal comfort scale: +3 (very comfortable), +2 (comfortable), +1 (just comfortable

2018 Clinical Trials

175. Transcranial Magnetic Stimulation for Attention Deficit/Hyperactivity Disorder (ADHD)

to complete study tasks and provide quality data, as determined by the Principal Investigator Low or borderline intellectual functioning - determined by a score of less than 90 on the Shipley Institute of Living Scale (SILS) (administered at Intake Visit). The SILS correlates with the Wechsler Adult Intelligence Scale-Revised (WAIS-R) Estimated Intelligence Quotient (IQ) Test Inability to provide informed consent Contacts and Locations Go to Information from the National Library of Medicine To learn more (...) is designed to mimic the appearance and sound of active TMS stimulation, but is equipped with a magnetic shield that reduces the strength of the field by approximately 80%. This reduction in field strength ensures that no neural stimulation occurs. Twenty sessions will be completed on sequential weekdays (5 days per week for 4 weeks). Outcome Measures Go to Primary Outcome Measures : Change in performance on Conners Adult ADHD Rating Scale - Self-Report: Long Version (ADHD symptoms) [ Time Frame: Week 4

2018 Clinical Trials

176. Participation-based Intervention on Community Participation and Parent Empowerment for Children With ASD

). Children have an IQ of at least 70 (as measured by Wechsler Intelligence Scale for Children). Parents agree to participate in this study and sign the consent form. Children over 7 years should provide written consent form. Exclusion Criteria: Children with unstable physical conditions within 3 months, such as cancer, having surgery, infection, or other active medical conditions. Children have known genetic conditions (e.g., Down syndrome, Fragile X Syndrome). Children have diagnosis associated (...) and follow-up at 24 weeks ] The COPM is a measure for identifying children's participation problems and prioritizing the goals. The parents will be asked to use a 10-point rating scales (1-10: higher scores indicating better performance and higher satisfaction) to rate their perception of performance and satisfaction of the goals. Change in the Goal Attainment Scaling (GAS) scores [ Time Frame: From baseline to post-intervention at 12 weeks and follow-up at 24 weeks ] The GAS is a measure for evaluating

2018 Clinical Trials

177. Long Term Follow up of Children Enrolled in the REDvent Study

Testing Detailed in person neuro-cognitive testing using standardized inventories using either the Battelle Developmental Inventory, second edition (Battelle-2) (age birth to 5 years 11 months) and the Wechsler Intelligence Scale for Children, fifth edition (WISC-5, for age 6 years to 19 years). Diagnostic Test: Emotional Health Assessment In person and written assessments of children and parents using the Behavioral Assessment System for Children, third edition (BASC-3) for children ≥ 2 years (...) and the UCLA PTSD Reaction Index (UCLA RI) for children ≥ 8 years. Diagnostic Test: Health Related Quality of Life Standardized instruments to assess (in person, over the phone, or via mail) health related quality of life in children. Parent and child questionnaires. Other Name: PEDS-QL Diagnostic Test: Functional Status Survey of overall functional status, administrated by asking a series of questions to patient and families. Other Name: Functional Status Scale Diagnostic Test: Respiratory Status

2018 Clinical Trials

178. Pre-Clinical White Matter Changes and Associated Connectivity Effects in Fabry Disease

fast bound-pool fraction imaging (FBFI), which is a technique better suited to capture and quantify these lesions, to study these lesions in patients with FD. In parallel, we would like to use functional MRI (fMRI) to study how these lesions alter brain function and connectivity in FD. Neuropsychological assessements will include Wechsler Adult Intelligence Scale, WAIS-III (Digit Span, Symbol-Digit/Coding, and Symbol Search), the Connors Continous Performance text (CPT-II). The Health Questionnaire (...) form, the Center for Epidemiologic Studies Depression Scale (CES-D), the RAND 36-Item Health Survey. Other Names: fmri FBFI Neuropsychological assessments Outcome Measures Go to Primary Outcome Measures : FBFI MRI using advanced MRI technique [ Time Frame: 6 months after enrollment closes ] advanced quantitative MRI technique (FBFI) to detect and quantify brain lesion in patients with FD Identify difference between patients with Fabry disease and healthy controls in brain function as measured

2018 Clinical Trials

179. Metformin for Motor and Cognitive Improvement in Children With Cerebral Palsy: A Feasibility Study

. As such, for this study, children between 5.0 to 6.5 years of age will not complete the CAVLT-2. Wechsler Scales of Intelligence [ Time Frame: Change in Wechsler Scales of Intelligence measures from baseline to 40 weeks ] The Wechsler Scales of Intelligence provide a brief measure of overall intelligence. WASI-II is applicable for people aged 6.0 to 90.11 years of age. For participants who are 5.0 to 5.9 years of age, the Wechsler Preschool and Primary Scale of Intelligence - Fourth Edition (WPPSI - IV) will be used (...) of the GMFM: the original 88-item GMFM, which yields a total score and scores in five dimensions (lying & rolling, sitting, crawling & kneeling, standing, walking, running & jumping); and the GMFM-66 (66 of the 88 items) with interval scaling. Individual items on the GMFM are scored on a 4-point ordinal scale; 1 indicates that the child initiates the task (completes < 10% of the activity); 2 indicates that the child partially completes the task (completes from 10 to 99% of the activity); 3 indicates

2018 Clinical Trials

180. Efficacy of Light Therapy Device LUMINETTE® in Major Depressive Disorder

cognitive impairment Stroop test [ Time Frame: week 10 ] test assessing the ability to inhibit cognitive interference Trail Making Test (TMT) [ Time Frame: week 10 ] test evaluating executive functions Wechsler Adult Intelligence Scale subtest (WAIS) [ Time Frame: week 10 ] test evaluating memory Eligibility Criteria Go to Information from the National Library of Medicine Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about (...) weeks. Device: placebo light therapy placebo portable light visor device Outcome Measures Go to Primary Outcome Measures : Montgomery-Åsberg depression rating scale (MADRS) [ Time Frame: week 8 ] Rating scale measuring depressive symptoms. Each item is scored from 0 to 3, yielding a total between 0 and 27. Secondary Outcome Measures : Pittsburgh Sleep Quality Index (PSQI) [ Time Frame: week 8 ] Self reported rating scale measuring quality of sleep Epworth Sleepiness Scale (ESS) [ Time Frame: week 8

2018 Clinical Trials

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