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Wechsler Intelligence Scale

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1561. Antipsychotic medication and cognitive function in schizophrenia. (PubMed)

between patients taking only atypical antipsychotics and those taking only conventionals. Neurocognitive functions were assessed in 67 patients with chronic schizophrenia and 92 controls using the Wechsler Memory Scale-Revised (WMS-R), the Wechsler Adult Intelligence Scale-Revised (WAIS-R), the Wisconsin Card Sorting Test (WCST), and the Advanced Trail Making Test (ATMT). Patients showed markedly poorer performance than controls on all these tests. Patients on non-standard antipsychotic medication

2006 Schizophrenia Research

1562. Loss of calculation abilities in patients with mild and moderate Alzheimer disease. (PubMed)

elderly controls.Tests of oral arithmetic (Wechsler Adult Intelligence Scale-Third Edition [WAIS-III] Arithmetic subtest) and written arithmetic (Wide Range Achievement Test-3 [WRAT-3] Arithmetic subtest) were administered, and overall group differences were examined. Errors on selected WRAT-3 problems were qualitatively analyzed across groups using a set of error codes.Patients with mild and moderate AD performed significantly below controls on both oral and written arithmetic tasks (P<.001

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2003 Archives of Neurology

1563. Hippocampal and entorhinal atrophy in mild cognitive impairment: prediction of Alzheimer disease. (PubMed)

obtained in a Cox model that also included Selective Reminding Test (SRT) delayed recall and Wechsler Adult Intelligence Scale-Revised (WAIS-R) Digit Symbol as predictors. Based on logistic regression models in the 3-year follow-up sample, for a fixed specificity of 80%, the sensitivities for MCI conversion to AD were as follows: age 43.3%, MMSE 43.3%, age + MMSE 63.7%, age + MMSE + SRT delayed recall + WAIS-R Digit Symbol 80.6% (79.6% correctly classified), hippocampus + entorhinal cortex 66.7%, age

2007 Neurology

1564. Behavioral disorders in pediatric epilepsy: unmet psychiatric need. (PubMed)

Behavioral disorders in pediatric epilepsy: unmet psychiatric need. This study examined the relation between psychiatric diagnosis and mental health services in children with epilepsy and the associated demographic, cognitive, linguistic, behavioral, and seizure-related variables.The Kiddie Schedule for Affective Disorders and Schizophrenia (K-SADS), the Child Behavior Checklist, the Test of Language Development, and the Wechsler Intelligence Scale for Children-Revised (WISC-R) were

2003 Epilepsia

1565. The effect of melperone, an atypical antipsychotic drug, on cognitive function in schizophrenia. (PubMed)

) were administered at baseline and after 6 weeks of melperone treatment. Treatment with melperone was associated with improvement in executive function, as measured by the Wisconsin Card Sorting Test (WCST)-Categories and WCST-Percent Perseveration. On the other hand, visuospatial manipulation, as measured by the Wechsler Intelligent Scale for Children-Revised (WISC-R) Maze, worsened during melperone treatment. There were no significant changes in other domains of cognition, i.e. verbal learning (...) in the treatment of some patients with neuroleptic-resistant schizophrenia. Other atypical antipsychotic drugs have been reported to improve cognitive function. This study was performed to investigate the effect of melperone on cognitive function. Nineteen patients with schizophrenia or schizoaffective disorder, including 11 neuroleptic-resistant patients, were treated with melperone for 6 weeks. A comprehensive neurocognitive test battery and psychopathological ratings (Brief Psychiatric Rating Scale, BPRS

2003 Schizophrenia Research

1566. Neurocognitive, behavioural and neurodevelopmental correlates of schizotypy clusters in adolescents from the general population. (PubMed)

schizotypy', and 'normal scorers'. Comparisons with ANOVAs showed that 'high schizotypes' performed poorly on neurocognition (Wechsler Intelligence Scales for Children-Revised (WISC-R) and Verbal Fluency (FAS)) and obtained the highest teacher ratings (TRF) of behavioural problems. 'Negative schizotypes' had the worst WCST results and more dermatoglyphic abnormalities. Both clusters had more neurological soft signs than 'normal scorers' and 'positive schizotypes'.Our results with community adolescents (...) on schizotypy dimensions and compare them on neurocognitive, behavioural, and neurodevelopmental markers.Two hundred seventy normal adolescents from the general population (mean age 13.4, SD=0.72) attending obligatory education were evaluated.A K-means iterative cluster analysis was performed with the Perceptual Aberration, Revised Social Anhedonia and Physical Anhedonia Scales. A forced four-cluster model yielded the following clusters: 'negative schizotypy', 'high or mixed schizotypy', 'positive

2003 Schizophrenia Research

1567. Episodic memory in schizophrenic patients and their relatives. (PubMed)

retention were investigated using the Logical Memory and Visual Reproduction tests of the Wechsler Memory Scale (WMS). A third subtest of the WMS, the Associate Learning and a visual analogue of it, the Abstract Paired Associates, were used to measure verbal and visual learning. Current general intellectual function was assessed using a five-subtest short-form of the Wechsler Adult Intelligence scale-Revised (WAIS-R).Schizophrenic patients performed significantly worse than controls on nearly all

2003 Schizophrenia Research

1568. Anomalous visual experiences, negative symptoms, perceptual organization and the magnocellular pathway in schizophrenia: a shared construct? (PubMed)

unmedicated patients with schizophrenia and 20 matched healthy control volunteers participated. Anomalous perceptual experiences were assessed with the Bonn Scale for the Assessment Basic Symptoms (BSABS). General intellectual functions were evaluated with the revised version of the Wechsler Adult Intelligence Scale. The 1-9 version of the Continuous Performance Test (CPT) was used to investigate sustained attention. The following psychophysical tests were used: detection of Gabor patches with collinear

2005 Psychological Medicine

1569. Factor analytic support for social cognition as a separable cognitive domain in schizophrenia. (PubMed)

processes. In the current study, the Wechsler Adult Intelligence Scale-Revised (WAIS-R) was administered to 169 males with schizophrenia, and test results were subjected to confirmatory factor analysis (CFA) to determine if those WAIS-R subtests containing social content would form a distinct Social Cognition (SC) factor. CFA was used to evaluate various models that hypothesized an SC factor, and for comparison purposes the same models were evaluated in the WAIS-R standardization sample. Results

2007 Schizophrenia Research

1570. Neuropsychological consequences of regular marijuana use: a twin study. (PubMed)

-using twins and their non-using co-twins were compared using a multivariate analysis of specific cognitive domains and univariate analyses of individual test scores. Dose response relationships were explored within the marijuana-using group.Marijuana-using twins significantly differed from their non-using co-twins on the general intelligence domain; however, within that domain only the performance of the block design subtest of the Wechsler Adult Intelligence Scale--Revised reached a level (...) in which neither twin used any other illicit drug regularly, were recruited from the Vietnam Era Twin Registry. A minimum of 1 year had passed since the marijuana-using twins had last used the drug, and a mean of almost 20 years had passed since the last time marijuana had been used regularly. Twins were administered a comprehensive neuropsychological test battery to assess general intelligence, executive functioning, attention, memory and motor skills. Differences in performance between marijuana

2004 Psychological Medicine

1571. Neurofibromatosis type 1: motor and cognitive function and T2-weighted MRI hyperintensities. (PubMed)

subjects matched for age, sex, and socioeconomic status for their IQ (Wechsler Intelligence Scale for Children-Revised [WISC-R] and Wechsler Adult Intelligence Scale-Revised [WAIS-R]), fine motor abilities (Motorische Leistungs-Serie [motor performance task]), and T2H (MRI).As a group, the 100 patients performed within normal limits of WISC-R and WAIS-R scores. However, the scores for the NF1 patients with normal MRI were at the mean, whereas those for the patients who had T2H (n = 58) were

2003 Neurology

1572. Visual memory predicts Alzheimer's disease more than a decade before diagnosis. (PubMed)

Visual memory predicts Alzheimer's disease more than a decade before diagnosis. Recent studies have suggested that AD may reflect a chronic process that begins many years before the clinical expression of dementia. The current study examines premorbid Benton Visual Retention Test (BVRT) and Wechsler Adult Intelligence Scale-vocabulary (WAIS-voc) test scores in order to determine whether long-term deficits in these tests can predict the development of AD decades later in the Baltimore

2003 Neurology

1573. A longitudinal neuropsychological study of partial brain radiation in adults with brain tumors. (PubMed)

classified as RT-treated nonprogressors (n = 12) or progressors (n = 3) based on serial follow-up structural imaging. Two patients received surgery only and served as controls to help minimize surgical, practice, test form, or other potential non-RT effects. Serial neuropsychological assessments were conducted using alternate forms of the Selective Reminding Test, 10/36 Spatial Recall Test, and Symbol Digit Modality Test (oral, written) as well as the Shipley Scale (baseline only), Wechsler Adult (...) Intelligence Scale-Revised Digit Span, Trail Making Test, and the Symptom Checklist-90-Revised Global Severity Index scale.There was evidence of subtle attention and memory improvement in RT-treated nonprogressors throughout the 2-year period, with no evidence of cognitive decline. In contrast, patients with disease progression evidenced more substantial decline in memory and attention.Partial brain fractionated RT was not associated with adverse neuropsychological effects through the first 2 years

2003 Neurology

1574. Influence of education on the relationship between white matter lesions and cognition. (PubMed)

, Digit Symbol Substitution Test of the Wechsler Adult Intelligence Scale-Revised, Finger Tapping Test, Word Fluency Test, and Raven Progressive Matrix. MRI scans were interpreted visually using a standardized scale for rating WMH.Severe WMH were present in 17% of the participants who had lower performances on tests involving attention tasks. In participants with a lower level of education, presence of severe WMH was significantly associated with lower cognitive performances. This was found for all

2003 Neurology

1575. Age at onset and cognitive functioning in schizophrenia. (PubMed)

Age at onset and cognitive functioning in schizophrenia. Impairments in cognitive functioning are common in schizophrenia, and the degree of impairment may be associated with the individual's age at onset of the disorder.To examine the effect of age at onset on cognitive functioning using the California Verbal Learning Test, sub-tests from the Wechsler Memory Scale-Revised and sub-scales from the Wechsler Adult Intelligence Scale-Revised among families with schizophrenia.The effect of age

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2004 British Journal of Psychiatry

1576. Executive functioning in children and adolescents with phenylketonuria. (PubMed)

-Kaplan EF Battery and on the Wechsler Abbreviated Scales of Intelligence to examine the relationship between EF skills, phe levels, age, and dietary adherence. At the time of the assessment, the mean age of participants was 14.8 years, mean lifetime phe levels ranged from 216 to 1200 microM (mean 594 microM); and concurrent phe levels ranged from 222 to 1730 microM (mean 660 microM). Children and adolescents with PKU showed lower performance in several EF skills: initiation of problem solving

2007 Clinical Genetics

1577. Cognitive impairment in patients with idiopathic normal pressure hydrocephalus. (PubMed)

on the orientation subtest of the Alzheimer's Disease Assessment Scale and on the general memory and delayed recall subtests of the Wechsler Memory Scale-Revised (WMS-R), and significantly lower on the attention/concentration subtest of the WMS-R and on the digit span, arithmetic, block design and digit symbol substitution subtests of the Wechsler Adult Intelligence Scale-Revised. The impairment of frontal lobe functions is disproportionately severe and memory impairment is disproportionately mild in patients

2006 Dementia and Geriatric Cognitive Disorders

1578. Association between physiological serum concentration of estrogen and the mental health of community-dwelling postmenopausal women age 70 years and over. (PubMed)

Depression and Anxiety Inventories (BDI and BAI) and the SF-36 Health Survey. Cognitive abilities were assessed with the cognitive subsection of the CAMDEX (CAMCOG), the Word Lists subtest of the Wechsler Memory Scale, and the Block Design and Verbal Fluency subtests of the Wechsler Adult Intelligence Scale. Estradiol- and estrone-sensitive immunoassays were used to measure serum estradiol and estrone.Women in the lowest 50th percentile of serum estradiol were more likely than women in the highest 50th

2005 The American Journal of Geriatric Psychiatry

1579. Intellectual efficiency of children with unilateral hearing loss. (PubMed)

Intellectual efficiency of children with unilateral hearing loss. The aim of our study was to observe the consequences of unilateral hearing loss with regard to intellectual functioning and development of children.The studies were conducted on the group of 64 children (42 boys and 22 girls) aged 6-16 years with left- or right-sided hearing loss using D. Wechsler Intelligence Scale for Children (WISC).Children with right-sided hearing loss had a limited range of concepts, lower capability (...) of learning verbal material and logical reasoning, abstract thinking and classifying. Left-sided hearing loss caused deterioration of intellectual abilities within non-verbal intelligence. Such a children had poorer abilities for analyzing, synthesizing and visual memory, worse spatial imagination and visual coordination.The examined children with unilateral hearing loss achieved the intelligence quotient on the average level in D. Wechsler Intelligence Scale. The side of hearing loss has a significant

2006 International Journal of Pediatric Otorhinolaryngology

1580. Feasibility of neuropsychological assessment in leukaemia patients shortly after diagnosis: directions for future prospective research. (PubMed)

' assessment.Mean scores on Wechsler Intelligence Scales did not differ significantly between patients and siblings; mean IQ scores for both the patients and the controls were high average. To examine specific neuropsychological functions, norm scores based on the exact age were acquired by fitting procedures, but no significant differences were found.Neuropsychological assessment of patients during early hospitalisation is feasible. The results indicate no adverse effect of illness and psychological factors (...) study. Treatment would include intrathecal and systemic chemotherapy according to the DCLSG ALL-9 protocol. Children were evaluated with an extensive neuropsychological battery including measures of intelligence, memory, attention, language, visual-constructive function, and fine-motor abilities within two weeks after start of the chemotherapy. The control group consisted of 29 healthy siblings (median age at testing 8.2 years, range 4-12), who were tested <4 weeks after the patients

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2005 Archives of Disease in Childhood

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