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Wechsler Intelligence Scale

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241. State and Trait Mediated Response to TMS in Substance Use Disorder

and learning disabilities may be associated with altered brain functioning in regions recruited during laboratory task performance. Cognitive impairment may affect one s ability to give informed consent. Assessment tool: Medical History and Wechsler Abbreviated Scale of Intelligence (WASI). IQ estimate must be 80 or over. Have coagulopathies, history of, current superficial, or deep vein thrombosis, musculoskeletal abnormalities restricting an individual s ability to lie flat for extended periods of time (...) not explicitly described in this criterion. Justification: Psychiatric disorders involve the central neural system (CNS) and, therefore, can be expected to alter the fMRI measures being used in this study. Assessment tools: M.I.N.I., Beck Depression Inventory, Beck Anxiety Inventory, Adult ADHD Self-Report Scales and clinical terview confirmation by clinician. Meet current DSM-5 criteria for moderate to severe substance use disorder, for alcohol or any drug (except nicotine for the smoker group). Past

2018 Clinical Trials

242. Metformin for Motor and Cognitive Improvement in Children With Cerebral Palsy: A Feasibility Study

. As such, for this study, children between 5.0 to 6.5 years of age will not complete the CAVLT-2. Wechsler Scales of Intelligence [ Time Frame: Change in Wechsler Scales of Intelligence measures from baseline to 40 weeks ] The Wechsler Scales of Intelligence provide a brief measure of overall intelligence. WASI-II is applicable for people aged 6.0 to 90.11 years of age. For participants who are 5.0 to 5.9 years of age, the Wechsler Preschool and Primary Scale of Intelligence - Fourth Edition (WPPSI - IV) will be used (...) of the GMFM: the original 88-item GMFM, which yields a total score and scores in five dimensions (lying & rolling, sitting, crawling & kneeling, standing, walking, running & jumping); and the GMFM-66 (66 of the 88 items) with interval scaling. Individual items on the GMFM are scored on a 4-point ordinal scale; 1 indicates that the child initiates the task (completes < 10% of the activity); 2 indicates that the child partially completes the task (completes from 10 to 99% of the activity); 3 indicates

2018 Clinical Trials

243. The Italian autism network (ITAN): a resource for molecular genetics and biomarker investigations. Full Text available with Trip Pro

and ADOS scales, cognitive assessment with Wechsler Intelligence Scale for Children or Preschool and Primary, Leiter International Performance Scale or Griffiths Mental Developmental Scale. Additional evaluations included language assessment, the Krug Asperger's Disorder Index, and instrumental examination such as EEG and structural MRI. DNA, RNA and plasma were collected from eligible individuals and relatives. A central laboratory was established to host the biorepository, perform DNA and RNA

2018 BMC Psychiatry

244. Child Neurodevelopmental Outcomes by Prepregnancy Body Mass Index and Gestational Weight Gain. Full Text available with Trip Pro

was categorized as normal (18.5-24.9), overweight (25.0-29.9), or obese (30 or greater). We also evaluated early (20 weeks of gestation or less), late (greater than 20 weeks of gestation), and total gestational weight gain and categorized gestational weight gain as inadequate, adequate, and excessive per 2009 Institute of Medicine guidelines. Neurodevelopmental outcomes included 5-year Wechsler Preschool and Primary Scale of Intelligence and 3-year Differential Ability Scales-II. Linear and logistic (...) of gestational weight gain, respectively. Maternal differences among the BMI categories included race-ethnicity, education, insurance type, parity, and thyroid status (all P<.01), whereas the gestational weight gain groups only differed by parity (P<.001). In unadjusted analysis, children of obese (93.2±12.8; 88.5±13.3) and overweight (94.1±15.6; 89.6±16.0) women had lower Wechsler Preschool and Primary Scale of Intelligence and Differential Ability Scales-II scores, respectively, than normal-weight women

2018 Obstetrics and Gynecology Controlled trial quality: predicted high

245. Local structural connectivity is associated with social cognition in autism spectrum disorder. Full Text available with Trip Pro

Wechsler Adult Intelligence Scale IV (WAIS-IV), Communication Checklist-Adult, Empathy Quotient, Social Responsiveness Scale and Behaviour Rating Inventory of Executive Function-Adult (BRIEF-A). In contradiction with the models of short-range over-connectivity in autism spectrum disorder, we found that patients with autism spectrum disorder had a significantly decreased anatomical connectivity in a component comprising 13 short tracts compared to controls. Specific short-tract atypicalities in temporal

2018 Brain

246. A novel mutation in the BCHE gene and phenotype identified in a child with low butyrylcholinesterase activity: a case report. Full Text available with Trip Pro

on chromosome 3, 3q26.1-q26.2, between nucleotides 165,490,692-165,555,260.This study describes a novel mutation in a child with BChE deficiency. In general, this child appeared healthy and well-developed with a normal appearance. However, the results of Wechsler Intelligence Scale showed that the full-scale intelligence quotient (FIQ) was 53, classified into the group with the minor defect. The BChE activity was 32.0 U/L, considerably lower than the normal lower limit (reference range: 5000-12,000 U/L

2018 BMC Medical Genetics

247. Comparisons of IQ in Children With and Without Cochlear Implants: Longitudinal Findings and Associations With Language. Full Text available with Trip Pro

evaluated nonverbal IQ in a multicenter, national sample of 147 children with CIs and 75 typically hearing peers. IQ was evaluated at baseline, prior to cochlear implantation, using the Bayley Scales of Infant and Toddler Development and the Leiter International Performance Scale. School-age IQ was assessed using the Wechsler Intelligence Scales for Children. For the current study, only the Perceptual Reasoning and Processing Speed indices were administered. Oral language was evaluated using (...) Comparisons of IQ in Children With and Without Cochlear Implants: Longitudinal Findings and Associations With Language. To make longitudinal comparisons of intelligence quotient (IQ) in children with cochlear implants (CIs) and typical hearing peers from early in development to the school-age period. Children with additional comorbidities and CIs were also evaluated. To estimate the impact of socioeconomic status and oral language on school-age cognitive performance.This longitudinal study

2018 Ear and hearing

248. Manual dexterity, but not cerebral palsy, predicts cognitive functioning after neonatal stroke. Full Text available with Trip Pro

of the Surveillance of CP in Europe network. Standardized tests (Nine-Hole Peg Test and Box and Blocks Test) were used to quantify manual (finger and hand respectively) dexterity. General cognitive functioning was evaluated with the Wechsler Intelligence Scale for Children, Fourth Edition. Simple and multiple linear regression models were performed while controlling for socio-economic status, lesion side, and sex.Fifteen children were diagnosed with CP. In simple regression models, both manual dexterity and CP

2018 Developmental Medicine and Child Neurology

249. Lower cognitive test scores at age 7 in children born with marginally low birth weight. Full Text available with Trip Pro

marginally LBW group and compared their results to 95 normal birth weight (NBW; 2501-4500 g) controls in an observational design. At 7 years, a pediatric psychologist tested the children using Wechsler Intelligence Scale for Children (WISC IV), Beery-Buktenica developmental test of Visual-Motor Integration (Beery VMI), and Test of Everyday Attention for Children (TEA-Ch).ResultsThe marginally LBW children had lower verbal comprehension intelligence quotient (IQ) (104 vs. 107, P=0.004), lower VMI scores

2018 Pediatric Research

250. Fatty fish intake and cognitive function: FINS-KIDS, a randomized controlled trial in preschool children. Full Text available with Trip Pro

was cognitive function measured by the Wechsler Preschool and Primary Scale of Intelligence, 3rd edition (WPPSI-III) and fine-motor coordination measured by the 9-Hole Peg Test (9-HPT) at pre- and post-intervention. Biological samples (blood, urine, hair), and questionnaires to the caregivers were included at both time points. Linear mixed effect models with a random intercept for kindergarten were used to analyze changes from pre- to post-intervention in the primary outcome variables.There were 218

2018 BMC Medicine Controlled trial quality: predicted high

251. Rehabilitation of Social Cognition in Subjects With Traumatic Brain Injury

[ Time Frame: 1 day ] To improve performance in phonemic fluency after receiving experimental intervention. This subtest has a puntuation range from 0 to 100, where higher values are considered to be a better outcome. Digit Span forward Subtest from the Wechsler Adult Intelligence Scale (WAIS-III) [ Time Frame: 1 day ] To improve performance in span of immediate verbal recall after receiving experimental intervention. This subtest has a puntuation range from 2 to 9, where higher values are considered (...) to be a better outcome. Digit Span backward Subtest from the Wechsler Adult Intelligence Scale (WAIS-III) [ Time Frame: 1 day ] To improve performance in working memory after receiving experimental intervention. This subtest has a puntuation range from 2 to 8, where higher values are considered to be a better outcome. Letter-Number Sequencing Subtest from the Wechsler Adult Intelligence Scale (WAIS-III) [ Time Frame: 1 day ] To improve performance in working memory after receiving experimental intervention

2018 Clinical Trials

252. Ready, Set, Goal: Motivation and Cognition in Stroke Patients

, Iowa: University of Iowa. Wechsler, D. (2008). Wechsler Adult Intelligence Scale-Fourth Edition. San Antonio, TX: Pearson. Layout table for additonal information Responsible Party: Dr. Richard H. Swartz, Principal Investigator, Sunnybrook Health Sciences Centre ClinicalTrials.gov Identifier: Other Study ID Numbers: 001 First Posted: April 27, 2018 Last Update Posted: April 27, 2018 Last Verified: April 2018 Individual Participant Data (IPD) Sharing Statement: Plan to Share IPD: No Plan Description (...) -subjects variable (goal-setting instructions versus standardized instructions) and a within-subjects variable (pre-post instructional manipulation). It is a one-time intervention lasting 1-2 hours. Investigators plan to enroll 72 patients in this study. All participants will complete neuropsychological measures to assess their baseline performance. The baseline measures include Trial 1 of the CVLT-II Alternate Form, the Digit Span Test, Center for Epidemiologic Studies Depression Scale, Controlled Oral

2018 Clinical Trials

253. Decision Making Study in Young and Middle-Aged Adults: Part II

Corporation; 1997. Wechsler D. Wechsler Adult Intelligence Scale, 3rd Edition. San Antonio, TX: Psychological Corporation; 1997. Rogers R, Monsell S. Costs of a predictible switch between simple cognitive tasks. Journal of experimental psychology: General. 1995;124(2):207-31. Park DC, Schwarz N, editors. Cognitive aging: A primer. Psychology Press, New York, NY, US; 2000. Carver CS, White TL. Behavioral Inhibition, Behavioral Activation, and Affective Responses to Impending Reward and Punishment: The BIS (...) cognitive and cerebral aging. Oxford University Press, New York, NY, US; 2005. p. 19-57. Kessler RM, Mason NS, Jones C, Ansari MS, Manning RF, Price RR. [18F]N-allyl-5-fluoropropylepidepride (fallypride): radiation dosimetry, quantification of striatal and extrastriatal dopamine receptors in man. NeuroImage. 2000Aug.26;11:S32. Stroop JE. Studies of interference in serial verbal reactions. J Exp Psychol Gen. 1935;:18643-62. Wechsler D. Wechsler Memory Scale, 3rd edition. San Antonio, TX: Psychological

2018 Clinical Trials

254. Memantine for the Treatment of Social Deficits in Youth With Disorders of Impaired Social Interactions

(ASD) diagnostic criteria as established by clinical diagnostic interview At least moderate severity of social impairment as measured by a total raw score of ≥85 on the parent/guardian-completed Social Responsiveness Scale-Second Edition (SRS-2)14 and a score of ≥4 on the clinician-administered Clinical Global Impression-Severity scale (CGI-S)17. Exclusion Criteria: IQ ≤70 based on the Wechsler Abbreviated Scale of Intelligence-II (WASI-II) Vocabulary and Matrix Reasoning subtests Impaired (...) group will receive a matched placebo pill with no active ingredients. This will be administered twice daily for 12 weeks. Drug: Placebo Participating children and adolescents with Non-Verbal Learning Disorder and related conditions (NVLD-RC) who meet the eligibility criteria will be randomly assigned to placebo for the course of the 12-week randomized controlled trial (RCT). Outcome Measures Go to Primary Outcome Measures : Clinical Global Impression-Improvement Scale (CGI-I) [ Time Frame: Baseline

2018 Clinical Trials

255. Determining Whether Multiple Anesthesia Exposures Affect Cognitive Function for Retinoblastoma Patients

with brain development in children who have never had anesthesia. Condition or disease Intervention/treatment Pediatric Retinoblastoma Retinoblastoma Other: Wechsler Intelligence Scale for Children, Fifth Edition (WISC-V) Other: California Verbal Learning Test, Children's Version Other: Beery Developmental Test of Visual Motor Integration, 6th edition Other: Grooved Pegboard Test Other: Behavior Assessment System for Children/Parent Report Study Design Go to Layout table for study information Study Type (...) : Other: Wechsler Intelligence Scale for Children, Fifth Edition (WISC-V) the WISC-V assessment produces a Full Scale IQ (FSIQ) used for primary power consideration in this study. The FSIQ is the most comprehensive global ability score on the WISC-V, and it has been conventionally reported and interpreted as an estimation of overall intellectual ability Other: California Verbal Learning Test, Children's Version Used to assess verbal learning and memory in children and adolescents Other: Beery

2018 Clinical Trials

256. RGX-111 Gene Therapy in Patients With MPS I

] Change from baseline in neurodevelopment [ Time Frame: Baseline, Week 24, Week 52 , Week 104 ] Change from baseline in neurodevelopment parameters of IQ as measured by the Wechsler Abbreviated Scale of Intelligence, 2nd Edition (WASI-II). Change from baseline in neurodevelopment [ Time Frame: Baseline, Week 24, Week 52 ] Change from baseline in neurodevelopment parameters of attention as measured by the Tests of Variables of Attention, Version 9 (TOVA). Eligibility Criteria Go to Information from

2018 Clinical Trials

257. SSM vs HEP in Late-Life Depression

(MoCA; London only) [ Time Frame: 0 weeks (baseline); 12 weeks; and 26 weeks ] The MoCA is a brief 30-item measure of different cognitive abilities (e.g. visuospatial ability, short-term memory). Scores range from 0-30, with scores above 26 indicating normal cognitive functioning. Wechsler Adult Intelligence Scale (WAIS-IV) -Test of premorbid functioning [ Time Frame: 0 weeks (baseline); 12 weeks; and 26 weeks ] WAIS-IV-Test of premorbid functioning is a test that assesses cognitive and memory (...) functioning. Performance on this test will be used to estimate a participant's Intelligence Quotient. Wechsler Adult Intelligence Scale (WAIS-IV)-Digit Span [ Time Frame: 0 weeks (baseline); 12 weeks; and 26 weeks ] WAIS-IV-Digit Span is an attention span task involving repeating digits in forward order, backward order, as well as sequencing digits in mind. Delis-Kaplan Executive Function System (D-KEFS) Color Word Test Conditions 1-3 [ Time Frame: 0 weeks (baseline); 12 weeks; and 26 weeks ] D-KEFS Color

2018 Clinical Trials

258. A Study of Identity Building in Children With ADHD

: baseline ] The Global Assessment of Functioning (GAF) is a numeric scale used by mental health clinicians and physicians to rate subjectively the social, occupational, and psychological functioning of an individual, e.g., how well one is meeting various problems-in-living. Scores range from 100 (extremely high functioning) to 1 (severely impaired). working memory [ Time Frame: baseline ] memory of numbers, memory of images in Wechsler Intelligence Scale for Children 5 executive functions [ Time Frame (...) the Damon and Hart's Self-Understanding Interview, exploring 7 identity domains: Physical, Active, Social, Psychological, Continuity, Agentivity, Distinction Self/Other. The severity of ADHD, neuropsychological functioning (attention, working memory, executive functions, long-term memory), self-esteem and internal/external attributive style (locus of control) will be assessed by validated scales. The overall level of identity development and in each dimension will be compared between patients

2018 Clinical Trials

259. Mechanism of Non-invasive Magnetic Stimulation

-report of special education classes, history of specific learning disability or mental retardation, Wechsler Abbreviated Scale of Intelligence (WASI), Medical history and Adult ADHD Self-Report Scale with follow up clinical interview. Contacts and Locations Go to Information from the National Library of Medicine To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor. Please refer to this study by its

2018 Clinical Trials

260. Internet-delivered Cognitive Behaviour Therapy for Sleep Problems in ASD

information Ages Eligible for Study: 13 Years to 17 Years (Child) Sexes Eligible for Study: All Accepts Healthy Volunteers: No Criteria Inclusion Criteria: Adolescents with a clinical ASD diagnosis based on the Diagnostic and Statistical Manual-fifth edition (DSM-5). Participants have been investigated with the Autism Diagnostic Observation Schedule (ADOS). Insomnia diagnosis or sleep problems according to DSM-5 Intelligence quotient (IQ) > 70 according to Wechsler Intelligence Scale for Children - fourth (...) that yields a quantitative index of sleep impairment and treatment outcome. Participants rate the following components on a 5-point Likert scale ranging from 0 (not at all) to 4 (extremely): (a) severity of sleep-onset, sleep-maintenance, and early morning awakening problems; (b) satisfaction with current sleep pattern; (c) interference with daily functioning; (d) noticeability of impairment attributed to the sleep problem; and (e) level of distress caused by the sleep problem. Total scores range from 0

2018 Clinical Trials

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