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Wart Treatment

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141. Low- and high-risk human papillomavirus genotype infections in intra-anal warts in HIV-positive men-who-have-sex-with-men. (PubMed)

Low- and high-risk human papillomavirus genotype infections in intra-anal warts in HIV-positive men-who-have-sex-with-men. Anogenital warts are often presumed to represent nondysplastic or low-grade anal intraepithelial neoplasia (LGAIN). We previously demonstrated that up to 20% of intra-anal warts in HIV-positive men who have sex with men (MSM) contain regions of high-grade AIN (HGAIN).To determine the causative human papillomavirus (HPV) types of low- and high- grade dysplastic areas (...) in warts from HIV-positive MSM.A total of 42 intra-anal warts from 41 HIV-positive MSM were graded as nondysplastic, LGAIN or HGAIN. Whole-tissue sections (WTS) were analysed with the SPF10 polymerase chain reaction/LiPA25 HPV genotyping system. If the WTS contained multiple HPV types, dysplastic regions were isolated by laser capture microdissection (LCM) for HPV genotyping.Overall, 38 of 42 (91%) WTS tested positive for HPV DNA. Of these, 23 (61%) contained a single HPV type and 15 (39%) contained

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2016 British Journal of Dermatology

142. Childhood skin and soft tissue infections: new discoveries and guidelines regarding the management of bacterial soft tissue infections, molluscum contagiosum, and warts. (PubMed)

Childhood skin and soft tissue infections: new discoveries and guidelines regarding the management of bacterial soft tissue infections, molluscum contagiosum, and warts. Pediatric skin and soft tissue infections (SSTIs) constitute a significant number of office-based pediatric visits. With SSTIs on the rise, it is not only important to effectively treat the individual, but to do so appropriately and cost-consciously. In this article, we highlight new research related to the treatment (...) of bacterial skin infections, molluscum contagiosum, and cutaneous warts, with the goal of guiding pediatricians in their practice against these common skin conditions.Recent data supports the use of topical antibiotics for noncomplicated impetigo. Systemic antibiotics covering gram-positive cocci are recommended for complicated cases of impetigo and deeper nonpurulent SSTIs. Localized purulent bacterial SSTIs can be treated with incision and drainage alone but more systemic involvement warrants treatment

2016 Current Opinion in Pediatrics

143. Clinicoepidemiological Study of Different Types of Warts (PubMed)

(28%), and housewives (16%) were the usual occupations. Cosmetic concern (92%), pain (16%), and itching (15%) were the common complaints. All patients of genital warts sought treatment within 6 months. Conclusions. Common, palmoplantar, and plane warts were the common types of nongenital warts. Overall prevalence peaked during the second decade but one-third of the cases of plane warts occurred during the first. Extremities were the most common sites (66.7%); face was the next commonly (23 (...) Clinicoepidemiological Study of Different Types of Warts Background. Warts are cutaneous and, sometimes, mucosal lesions caused by one of the several human papilloma viruses. Aim. Assessment of the clinicoepidemiological aspects of warts. Materials and Methods. One hundred consecutive patients of warts presenting to the department of our institution were assigned two broad locational groups: genital and nongenital warts, the latter subdivided into common, plane, palmoplantar, mosaic

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2016 Dermatology research and practice

144. Plantar Wart

(pared) Painless on lateral pressure Retain normal fingerprint lines (warts do not) Contrast with pinpoint blood vessels of Plantar Warts Foreign body reaction (sheering in sports) Epithioma cuniculatum (verrucous carcinoma) IX. Precautions No treatment needed if asymptomatic Avoid aggressive technique Surgical excision X. Management ral Topical treatments require 2-3 months for eradication Relieve pressure on wart area with pads Soak foot before application of salicylic acid Soak in warm water (...) years without treatment Recurrence after treatment is common XIII. References Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term "Plantar Wart." Click on the image (or right click) to open the source website in a new browser window. Related Studies (from Trip Database) Ontology: Plantar wart (C0042548) Definition (NCI) A wart in the plantar surface of the foot. It is caused by human papillomavirus. Concepts Disease or Syndrome ( T047

2018 FP Notebook

145. Genital Wart

-related malignancy See prognosis below VIII. Management: Overall treatment strategy Non-Keratinized Warts First line: or Alternative: Refractory: , TCA, ablation Keratinized warts First line Warts <10 mm: Warts >10 mm: Surgical excision (or if persistent) Adjunctive: applied as pretreatment Warts on mucosal surface (Vagina, , anal) First line: Alternative: Trichloroacetic Acid Pregnancy Indications for HPV treatment in pregnancy Treat only lesions that would obstruct labor or result in significant (...) Solution is left on skin for 1-4 hours and then washed off Similar clearance rates and recurrence to self applied agents listed above FDA category X Toxicity risk (deaths have occurred) Limit application area to <10 cm^2 Limit amount applied to <0.5 ml per treatment Trichloroacetic acid (TCA) 60-90% compounded solution (or Bichloroacetic Acetic Acid or BCA) Apply to each wart up to three times weekly until resolution Allow to dry (lesion will "frost" or turn white) Solution is liquidy and easily

2018 FP Notebook

146. Wart Immune Therapy

: Wart Immune Therapy , Intralesional Candida Injection From Related Chapters II. Indication s refractory to other treatments Not FDA approved (anecdotal support only) III. Preparation Killed Candida (Monilia albicans) Used in Manitou control (1:1000 solution) IV. Application Preparation Mix equal parts of 1% without Use 30 gauge needle Choose largest wart Injection Inject 0.1 cc to 0.3 cc intradermal beside wart Wart should blanche with injection V. Precautions Wear protective glasses Limit to 3 (...) Wart Immune Therapy Wart Immune Therapy Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Wart Immune Therapy Wart Immune Therapy Aka

2018 FP Notebook

147. Effectiveness Study of Human Papilloma Virus (HPV) Vaccines to Prevent Recurrence of Genital Warts

, however unique problems posed by large or extensive genital warts are not so easily solved and treatment of affected patients remains very challenging. Recurrences are common especially among immune-compromised women. This study will test whether giving the quadrivalent human papilloma virus (HPV) vaccine to women with extensive genital warts prior to surgical treatment will improve outcomes. Investigators hypothesize that pre-treatment with HPV vaccine can play a role in the control of both malignant (...) and benign HPV disease in women with and without HIV infection through stimulation of the antibody response. In addition, HPV types and other associated diseases will be studied in women receiving HPV vaccine and placebo. Condition or disease Intervention/treatment Phase Genital Warts Biological: Quadrivalent HPV vaccine Biological: Hepatitis B vaccine Phase 3 Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Estimated Enrollment : 75 participants

2016 Clinical Trials

148. Exploratory Study of Efficacy and Safety of Ingenol Mebutate 0.05% Gel for Common Warts on the Hands.

Sponsor: Neal D. Bhatia, MD Collaborator: LEO Pharma Information provided by (Responsible Party): Neal D. Bhatia, MD, TCR Medical Corporation Study Details Study Description Go to Brief Summary: The purpose of this study is to determine if ingenol mebutate 0.05% gel is safe and effective in treating common warts on the hands. Condition or disease Intervention/treatment Phase Verruca Vulgaris Common Warts Drug: ingenol mebutate 0.05% gel Phase 1 Detailed Description: This is an open label exploratory (...) study evaluating the efficacy and safety of ingenol mebutate 0.05% gel for the treatment of verruca vulgaris. The study will be conducted at one site with one investigator, all subjects will receive active drug. Prior to the application of the investigational product (IP) on Day 1, the individual warts will be pared down with a 15 blade up to obtain debridement of intact skin to maximize exposure and allow for effective penetration of therapy into the lesion. Subjects can be screened for the study

2016 Clinical Trials

149. Biofields Therapy on Warts

to magnetize). The "fake" biofield therapist, placebo, has been trained to replicate gestures during a training validated by an independent recognized biofield therapist. Condition or disease Intervention/treatment Phase Wart Energy Medecine Magnetism Other: True Biofield therapy Other: Fake Biofield therapy Not Applicable Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Actual Enrollment : 62 participants Allocation: Randomized Intervention Model: Parallel (...) Assignment Masking: Triple (Participant, Investigator, Outcomes Assessor) Primary Purpose: Treatment Official Title: Effect of the Intervention of Biofields Therapy on Warts of the Hands and Feet in Adults: a Prospective, Randomized, Double-blind Trial Study Start Date : April 2016 Actual Primary Completion Date : November 2018 Actual Study Completion Date : November 2018 Resource links provided by the National Library of Medicine related topics: Arms and Interventions Go to Arm Intervention/treatment

2016 Clinical Trials

150. Active-Controlled Study to Assess the Efficacy and Safety of DFD-05 in Subjects With Common Warts

: Dr. Reddys Laboratories, SA Information provided by (Responsible Party): Dr. Reddys Laboratories, SA Study Details Study Description Go to Brief Summary: DFD05 vs. Active01 in the treatment of common warts Condition or disease Intervention/treatment Phase Common Warts Drug: DFD05 Cream Drug: Active01 Cream Phase 2 Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Actual Enrollment : 50 participants Allocation: Randomized Intervention Model (...) Measures : The proportion of subjects categorized as treatment responders (defined as having at least 91% reduction in surface area, averaged across all target warts) [ Time Frame: Visit 5 (week 12) ] Eligibility Criteria Go to Information from the National Library of Medicine Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study

2016 Clinical Trials

151. Laser and light therapy for facial warts: a systematic review. (PubMed)

Laser and light therapy for facial warts: a systematic review. Facial verruca plana, or flat warts, are benign skin papillomas caused by human papillomavirus infections. A large portion of cases are refractory to treatment and can cause psychosocial distress in patients. Laser and light modalities offer an alternative therapeutic approach that has not been extensively explored. We systematically reviewed PubMed for studies describing treatment of facial verruca plana using lasers, photodynamic (...) therapy and infrared coagulation. Final inclusion and review of eighteen studies suggests laser and light therapies to have considerable potential in the treatment of this recalcitrant condition. In particular, yttrium aluminium garnet lasers, infrared coagulation and photodynamic therapies have been reported to demonstrate efficacy. Further studies with larger power are required to determine which method should be established as the alternative treatment of choice for recalcitrant facial verrucae.©

2016 Journal of the European Academy of Dermatology and Venereology : JEADV

152. Multiple Human Papillomavirus Infection Is Associated with High-Risk Infection in Male Genital Warts in Ulsan, Korea (PubMed)

clinics in Ulsan, Korea, for the treatment of genital warts between April 2014 and January 2015. All patients underwent HPV genotyping. The prevalence and characteristics of HPV infection were analyzed, and the patterns of HPV infection according to age were assessed. Among the study patients, 13 (16.3%) were negative for HPV infection, 46 (57.3%) were infected with low-risk HPV, and 21 (26.3%) were infected with high-risk HPV. Patients with multiple HPV infection were more likely to have high-risk (...) Multiple Human Papillomavirus Infection Is Associated with High-Risk Infection in Male Genital Warts in Ulsan, Korea Further understanding of male human papillomavirus (HPV) infection is necessary to prevent infection in men, as well as transmission to women. In our current study, we investigated patterns of HPV infection and genotype distributions in male genital warts using the Anyplex II HPV28 Detection kit. We reviewed the medical records of 80 male patients who presented to 5 neighborhood

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2016 Journal of Korean medical science

153. Self-administered interventions for anogenital warts in immunocompetent patients: a systematic review and meta-analysis. (PubMed)

Self-administered interventions for anogenital warts in immunocompetent patients: a systematic review and meta-analysis. Anogenital warts (AGWs, condylomata acuminata) are among the most common STIs and may severely impact quality of life (QoL). Available treatment options are characterised by a high proportion of non-responders and recurrences.To systematically review and meta-analyse the available evidence from randomised controlled trials (RCTs) on topical treatments for AGWs considering (...) to podophyllotoxin 0.5% solution with respect to CC. No significant differences were detected between imiquimod 5% cream and podophyllotoxin 0.5% solution and between polyphenon E 10% and 15% ointment. No data on the influence on health-related QoL were available.Our confidence in the pooled estimates (GRADE quality of the evidence) ranged from very low to high. Apart from the given results, other aspects such as availability, costs or patient preference have to be considered when making a treatment choice. Due

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2016 Sexually transmitted infections

154. A meta-analysis of the use of diphencyprone immunotherapy for the treatment of cutaneous warts

A meta-analysis of the use of diphencyprone immunotherapy for the treatment of cutaneous warts Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email salutation (e.g. "Dr Smith" or "Joanne") for correspondence: Organisation web address (...) is the typical model of choice for pre-clinical meta-analyses. This is because in the fixed-effect model, it is assumed that the differences in observed effect between studies is solely due to sampling error (i.e. differences in sample size), and that the true effect is the same (fixed) across all studies. However, this assumption is unlikely to hold true for data from animal studies, which generally include various species, strains and treatment regimes, for which different true effects are likely to exist

2018 PROSPERO

155. Intralesional Cidofovir for the Treatment of Recalcitrant Warts in the Pediatric Immune-suppressed Population.

Intralesional Cidofovir for the Treatment of Recalcitrant Warts in the Pediatric Immune-suppressed Population. Intralesional Cidofovir for the Treatment of Recalcitrant Warts in the Pediatric Immune-suppressed Population. - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved (...) studies (100). Please remove one or more studies before adding more. Intralesional Cidofovir for the Treatment of Recalcitrant Warts in the Pediatric Immune-suppressed Population. The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02567149 Recruitment Status : Withdrawn (No funding) First Posted : October

2015 Clinical Trials

156. Nanopulse Efficacy Study for the Treatment of Common Warts

Nanopulse Efficacy Study for the Treatment of Common Warts Nanopulse Efficacy Study for the Treatment of Common Warts - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Nanopulse Efficacy Study (...) for the Treatment of Common Warts The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02650466 Recruitment Status : Completed First Posted : January 8, 2016 Last Update Posted : March 29, 2017 Sponsor: University of Southern California Information provided by (Responsible Party): Stefani Takahashi, University

2015 Clinical Trials

157. Systemic retinoids for the treatment of warts

Systemic retinoids for the treatment of warts Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email salutation (e.g. "Dr Smith" or "Joanne") for correspondence: Organisation web address: Timing and effect measures Timing and effect (...) for pre-clinical meta-analyses. This is because in the fixed-effect model, it is assumed that the differences in observed effect between studies is solely due to sampling error (i.e. differences in sample size), and that the true effect is the same (fixed) across all studies. However, this assumption is unlikely to hold true for data from animal studies, which generally include various species, strains and treatment regimes, for which different true effects are likely to exist. The random-effects

2018 PROSPERO

158. Systematic review and meta-analysis of randomised control trial (RCT) evidence for the efficacy, safety and tolerability of treatments for anal warts

Systematic review and meta-analysis of randomised control trial (RCT) evidence for the efficacy, safety and tolerability of treatments for anal warts Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email salutation (e.g. "Dr Smith (...) various species, strains and treatment regimes, for which different true effects are likely to exist. The random-effects model takes into account both the within-study (sampling error) and between-study (differences in the true effect size) variance. Should the excessive between-study variance be very low or zero, the random-effects model will yield the same results as the fixed-effect model. For further details, see the and to pre-clinical meta-analysis. Example: Because of the exploratory nature

2018 PROSPERO

159. Topical NVN1000 for the Treatment of External Genital and Perianal Warts

Topical NVN1000 for the Treatment of External Genital and Perianal Warts Topical NVN1000 for the Treatment of External Genital and Perianal Warts - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Topical (...) NVN1000 for the Treatment of External Genital and Perianal Warts The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02462187 Recruitment Status : Completed First Posted : June 3, 2015 Last Update Posted : October 15, 2018 Sponsor: Novan, Inc. Collaborator: PPD Information provided by (Responsible Party

2015 Clinical Trials

160. ALC-919 For The Treatment Of Common Warts

ALC-919 For The Treatment Of Common Warts ALC-919 For The Treatment Of Common Warts - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. ALC-919 For The Treatment Of Common Warts The safety and scientific (...) , randomized, double blind, vehicle-controlled phase 2 study of subjects 8 years of age and older with Common Warts (Verruca vulgaris) who desire treatment. Condition or disease Intervention/treatment Phase Verruca Vulgaris Drug: 2014-ALC-919-US Drug: Vehicle-Control Topical Solution Phase 2 Detailed Description: This is a single-center, randomized, double blind, vehicle-controlled phase-2 study of subjects 8 years of age and older with Common Warts (Verruca vulgaris) who desire treatment. A total of four

2015 Clinical Trials

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