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Wart Treatment

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61. Treatment of Athlete's Plantar Warts Using a Botanical Blend: A Case Report. (Abstract)

Treatment of Athlete's Plantar Warts Using a Botanical Blend: A Case Report. Context • Viral plantar warts, or verruca plantaris, are a benign epithelial tumor caused by various strains of the human papilloma virus (HPV). Current treatments have had mixed degrees of success, are moderately invasive, and are often incompatible with participation in sports. Objective • The study intended to examine the benefits of treating plantar warts with a topical, botanical blend that has had clinical (...) in presentation by the fifth day of treatment. At 1-mo postintervention, or day 90, the epidermal tissue was asymptomatic and devoid of petechiae, malformations, or visible infection. Conclusions • The results of the current case study directly contrast with the drawbacks of commonly accepted, first-line interventions in the treatment of viral plantar warts and, in many respects, demonstrate better efficacy and fewer side effects than the standard of care. The positive results also highlight the necessity

2017 Alternative Therapies in Health & Medicine

62. Morphological characteristics and HPV genotype predict the treatment response in cutaneous warts. Full Text available with Trip Pro

Morphological characteristics and HPV genotype predict the treatment response in cutaneous warts. Cutaneous warts have a cure rate after therapy of no more than approximately 50%. Recently, we developed and validated a standard assessment tool for warts (Cutaneous WARTS diagnostic tool, CWARTS) based on phenotypical characteristics.To assess whether patient and morphological wart characteristics predict the human papillomavirus (HPV) type in a specific wart and whether these characteristics (...) as well as the HPV type predict a favourable treatment response.Photographs were used to score nine morphological wart characteristics using the newly developed CWARTS tool. Genotyping of 23 wart-associated HPV types was performed using the hyperkeratotic skin lesion-polymerase chain reaction/multiplex genotyping assay. The results were correlated with a favourable response to treatment with monochloroacetic acid, cryotherapy or a combination of cryotherapy and salicylic acid. Odds ratios were

2017 British Journal of Dermatology Controlled trial quality: uncertain

63. Pulsed Dye Laser Therapy in the Treatment of Warts: A Review of the Literature. (Abstract)

Pulsed Dye Laser Therapy in the Treatment of Warts: A Review of the Literature. Warts or verrucae vulgaris are common cutaneous infections with currently no definitive curative treatments available.To determine the efficacy of pulsed dye laser (PDL) in the treatment of warts.A literature search was performed using the PubMed and MEDLINE databases. A search using {(Wart[s], verruca or condylomata)} AND [(Pulsed dye laser)] was used. Forty-four articles were identified as relevant (...) been described as very few and rare, the main ones being topical discomfort and erythema.Pulsed dye laser is a safe and effective modality in the treatment of warts that can be applied to most body parts. Cost and availability remain a limitation to the use of PDL; however, this modality can be used when other more traditional and accessible treatments have failed.

2017 Dermatologic Surgery

64. Small cryotherapy devices for the treatment of skin warts. (Abstract)

Small cryotherapy devices for the treatment of skin warts. Effectiveness of cryotherapy on skin wart models.Two small cryotherapy devices, Wartner and Wortie, were administered for 10″-60″ on tomatoes and potatoes used as skin wart models. Frozen surface and depth were evaluated by standardized photography and computer analysis. Tissue temperature at depths of 0.1-10 mm was assessed by an electronic thermometer during treatment.Cryotherapy induced a transient freezing of the tomato surface

2017 Journal of Dermatological Treatment

65. Cryotherapy plus oral zinc sulfate versus cryotherapy plus placebo to treat common warts: A double blind, randomized, placebo-controlled trial Full Text available with Trip Pro

Cryotherapy plus oral zinc sulfate versus cryotherapy plus placebo to treat common warts: A double blind, randomized, placebo-controlled trial Cutaneous warts are caused by a small group of specific types of human papillomaviruses. Cryotherapy is a highly effective treatment for patients with viral warts; however, it is a painful method and usually requires several treatment sessions. Zinc is a trace element with many proven effects on the immune system.Our aim was to assess the efficacy (...) and safety of oral zinc sulfate in the treatment and recurrence rate of common warts.Eighty-three patients with common warts participated in this double-blind, randomized, placebo-controlled trial. In both groups, three sessions of liquid nitrogen cryotherapy were performed for up to 2 months with 3-week intervals. The treatment group (n = 45) received oral zinc sulfate capsules in a dose of 10 mg/kg per day up to 600 mg day. The control group (n = 38) was provided with placebo of similar appearance

2017 International journal of women's dermatology Controlled trial quality: predicted high

66. Functional characterization of CD4 and CD8 T cell responses among human papillomavirus infected patients with ano-genital warts Full Text available with Trip Pro

for the treating physician. The conventional treatment options are targeted only to the local site of warts. There is no systemic treatment modality as there is limited understanding of the disease immune-pathogenesis. The role of cell-mediated immunity in combating HPV infection is not clearly defined. Hence the present study is aimed at investigating the CD4+ T helper (Th1 and Th2) and CD8+ T cell responses among wart patients. In this study, we compared HPV6 and HPV11 antigen-specific T cell responses among (...) function correlated with poor wart clearance. Our findings open future avenues for exploring potential immunomodulation strategies as an adjunct to standard treatment for better management of these patients and prevention of recurrence.

2017 Virusdisease

67. Acid, freeze, or duct tape: What works best for common warts?

24, 2016 Acid, freeze, or duct tape: What works best for common warts? Clinical Question: What is the efficacy of commonly used treatments for non-genital warts? Bottom-line: Highest quality primary care evidence finds warts resolve with cryotherapy (39%) and salicylic acid (24%) more than no treatment (16%) at 13 weeks. Cryotherapy has more pain and blistering (up to ~80%), but greater patient satisfaction (~70%). Evidence for duct tape is limited and inconsistent. Evidence: • Highest-quality (...) primary care Randomized Controlled Trial (RCT): 1 240 children and adults, new warts, cryotherapy (2-10 seconds via cotton applicator three times every two weeks), daily 40% salicylic acid (SA), or no treatment. Cure at 13 weeks: o All warts: Cryotherapy 39%, SA 24%, no treatment 16%. ? Versus no treatment: SA Number Needed to Treat (NNT)=13, cryotherapy NNT=5. o Plantar warts: Cryotherapy 30%, SA 33%, no treatment 23% (none statistically significant): ? No patient >12 years old had spontaneous

2016 Tools for Practice

68. Warts and Verrucae

Warts and Verrucae Wart and verruca treatment options | Patient TOPICS Try our Symptom Checker TREATMENT RESOURCES Try our Symptom Checker PROFESSIONAL Upgrade to Patient Pro / / Search Wart and verruca treatment options Authored by Reviewed by Warts are very common and usually harmless. Warts on the feet are called verrucas (or verrucae) and are sometimes painful. Warts and verrucas usually disappear without treatment but can remain for a long time. There are a number of different treatments (...) that can help to get rid of them more quickly. There are three options for the management of : Do not treat them . If warts don't bother you, there is no reason for active treatment. Use home treatment . There are a number of home treatments to try, including: Covering them up (occlusion). Chemical burning (salicylic acid). Freezing (cryotherapy). Liquid nitrogen cryotherapy (intensive freezing) or minor surgery . There is no perfect treatment with no risks so it's important to consider which treatment

2015 SickKids Reports

69. UK National Guidelines on the Management of Anogenital Warts

and is retrospectively applicable to guidance produced using the processes described in the BASHH Framework for Guideline Development and Assessment dated September 2010. More information on accreditation can be viewed at www.evidence.nhs.uk 2 ? Search strategy OVID/Medline was searched for the years 1966-2013 using keywords "human papillomavirus," "genital warts," "epidemiology," "clinical manifestations," "treatment," "management”. ? Methods Article titles and abstracts were screened for relevance and the full (...) be advisable to take a biopsy for histological verification in cases that do not respond to treatment. Examination of the genitalia and perianal skin is essential to recognise the full extent of the warts. In the presence of perianal warts, a proportion of patients will have warts in the anal canal. If patients have anal symptoms such as irritation or discharge, it is recommended to examine the anal canal. Some patients present with intraepithelial neoplastic lesions in the anogenital region, either

2015 British Association for Sexual Health and HIV

70. Systemic retinoids for the treatment of warts

Systemic retinoids for the treatment of warts Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email salutation (e.g. "Dr Smith" or "Joanne") for correspondence: Organisation web address: Timing and effect measures Timing and effect (...) for pre-clinical meta-analyses. This is because in the fixed-effect model, it is assumed that the differences in observed effect between studies is solely due to sampling error (i.e. differences in sample size), and that the true effect is the same (fixed) across all studies. However, this assumption is unlikely to hold true for data from animal studies, which generally include various species, strains and treatment regimes, for which different true effects are likely to exist. The random-effects

2018 PROSPERO

71. Systematic review and meta-analysis of randomised control trial (RCT) evidence for the efficacy, safety and tolerability of treatments for anal warts

Systematic review and meta-analysis of randomised control trial (RCT) evidence for the efficacy, safety and tolerability of treatments for anal warts Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email salutation (e.g. "Dr Smith (...) various species, strains and treatment regimes, for which different true effects are likely to exist. The random-effects model takes into account both the within-study (sampling error) and between-study (differences in the true effect size) variance. Should the excessive between-study variance be very low or zero, the random-effects model will yield the same results as the fixed-effect model. For further details, see the and to pre-clinical meta-analysis. Example: Because of the exploratory nature

2018 PROSPERO

72. Wart Treatment

Wart Treatment Wart Treatment Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Wart Treatment Wart Treatment Aka: Wart Treatment , Wart (...) Management From Related Chapters II. Precautions Avoid over-treatment May result in painful scar worse than wart! Expect only 60-70% success with only 1 treatment III. Management: Home General Measures Debriding or paring down callus Use rasp or lava stone with care - stop if irritation Tools Emery board Lava stone or pumice stone Avoid Blades! Hands Warm water soaks (50-70% efficacy) : 45 C = 113 F Use candy thermometer to avoid burns Fifteen to thirty minutes per time as tolerated Repeat 2-3 times per

2018 FP Notebook

73. A meta-analysis of the use of diphencyprone immunotherapy for the treatment of cutaneous warts

A meta-analysis of the use of diphencyprone immunotherapy for the treatment of cutaneous warts Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email salutation (e.g. "Dr Smith" or "Joanne") for correspondence: Organisation web address (...) is the typical model of choice for pre-clinical meta-analyses. This is because in the fixed-effect model, it is assumed that the differences in observed effect between studies is solely due to sampling error (i.e. differences in sample size), and that the true effect is the same (fixed) across all studies. However, this assumption is unlikely to hold true for data from animal studies, which generally include various species, strains and treatment regimes, for which different true effects are likely to exist

2018 PROSPERO

74. Efficacy and safety of the combination of ablative therapy and self-administered treatment versus ablative therapy alone for warts: a systematic review and meta-analysis

Efficacy and safety of the combination of ablative therapy and self-administered treatment versus ablative therapy alone for warts: a systematic review and meta-analysis Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email salutation (...) various species, strains and treatment regimes, for which different true effects are likely to exist. The random-effects model takes into account both the within-study (sampling error) and between-study (differences in the true effect size) variance. Should the excessive between-study variance be very low or zero, the random-effects model will yield the same results as the fixed-effect model. For further details, see the and to pre-clinical meta-analysis. Example: Because of the exploratory nature

2018 PROSPERO

75. Risk factors for cutaneous warts and the influence factors of curative effect of 5-flurouracil therapy in southern China. (Abstract)

Risk factors for cutaneous warts and the influence factors of curative effect of 5-flurouracil therapy in southern China. Background: To systematically explore the risk factors of cutaneous warts and influence factor for the effectiveness of 5-fluorouracil (5-FU). Methods: This is a case-control study of 408 cutaneous warts patients and 408 controls of Chinese Han population in southern China. In addition, 244 patients who presented with an initial episode of warts without treatment were (...) and twenty-seven patients in 244 (93.03%) were successfully treated with 5-FU. Multivariate analysis indicated that smoking, alcohol intake, severe psychological stress, more than six months' duration of cutaneous warts, lesions on foot and warts diameter ≥5 mm adversely affected the effectiveness of 5-FU. Conclusions: The newly identified risk factors for cutaneous warts and influence factors for efficacy of 5-FU provided clues for warts prevention and treatment of Chinese Han population.

2019 Journal of Dermatological Treatment

76. Position statement for the diagnosis and management of anogenital warts. Full Text available with Trip Pro

warts should use immunotherapy for 2 months followed by ablation and a second 2-month course of immunotherapy. Guidance for daily practice situations and the subsequent action that can be taken, as well as an algorithm for treatment of large warts, were also created.The guidance provided will help physicians with the diagnosis and management of AGW in order to improve the health and quality of life of patients with AGW.© 2019 The Authors Journal of the European Academy of Dermatology and Venereology (...) Position statement for the diagnosis and management of anogenital warts. Anogenital warts (AGW) can cause economic burden on healthcare systems and are associated with emotional, psychological and physical issues.To provide guidance to physicians on the diagnosis and management of AGW.Fourteen global experts on AGW developed guidance on the diagnosis and management of AGW in an effort to unify international recommendations. Guidance was developed based on published international and national

2019 Journal of the European Academy of Dermatology and Venereology

77. Serum retinol-binding protein: a novel biomarker for recalcitrant cutaneous warts. (Abstract)

Serum retinol-binding protein: a novel biomarker for recalcitrant cutaneous warts. Cutaneous viral warts are benign epidermal proliferations caused by human papillomaviruses (HPVs). Despite treatment, a significant proportion of warts fail to resolve, becoming recalcitrant. Vitamin A (retinol) may disrupt the interplay of HPV replication and epithelial cell differentiation, allowing normal tissue to replace warts. Circulating retinol-binding protein (RBP) concentrations highly correlate (...) with retinol levels.We aimed at evaluation of serum RBP level in patients with recalcitrant cutaneous warts in order to assess its correlation with disease pathogenesis.Serum RBP level was measured by an ELISA technique in 50 patients with recalcitrant cutaneous warts and 30 apparently healthy controls.Serum RBP level was significantly lower in patients with recalcitrant warts than the control group (P < 0.001). However, it did not differ regarding different clinical parameters in studied patients (P

2019 International Journal of Dermatology

78. Evaluation of different concentrations of hydrogen peroxide solution (3% and 6%) as a potential new therapeutic option of nongenital warts: A randomized controlled triple-blinded clinical trial. (Abstract)

Evaluation of different concentrations of hydrogen peroxide solution (3% and 6%) as a potential new therapeutic option of nongenital warts: A randomized controlled triple-blinded clinical trial. Warts are common viral skin infections caused by human papillomavirus. None of the available treatment modalities fulfills the criteria of an ideal treatment option.To evaluate the efficacy and safety of hydrogen peroxide (HP) 3% and 6% solution as a topical treatment of nongenital warts.This (...) prospective randomized controlled study included 145 patients with nongenital warts. They were divided into three groups. Group 1 used topical hydrogen peroxide 6% solution under occlusion with a plastic tape for one hour daily for 6 weeks, group 2 used hydrogen peroxide 3% solution, and group 3 used normal saline 0.9% as a placebo. Patients were evaluated at the third and sixth weeks of treatment and 12 weeks after treatment completion.Treatment responses were significantly better in groups 1 and 2 than

2019 Journal of cosmetic dermatology Controlled trial quality: uncertain

79. Comparing the effects of shallomin lotion and cryotherapy on treating plane warts. Full Text available with Trip Pro

Comparing the effects of shallomin lotion and cryotherapy on treating plane warts. Wart is a common transferable skin disease that is caused by human papilloma virus. Choosing the best treatment method can vary based on age, therapeutic goal, complications, and wart place. Due to antibacterial effect of shallomin (hirtifolium Boiss extract) and since its effect has not been studied yet, it was compared to cryotherapy therapeutic methods for treating patients with plane warts.The present study (...) to cryotherapy, shallomin could not lead to a significant decrease in the size and number of warts.According to the results of this study, which is the first and the only investigation into the effects of shallomin on treating plane warts, it can be stated that despite of its antibacterial, antifungal, and anti-herpetic properties, shallamin cannot be a clinically effective option for treating plane warts.

2019 Journal of family medicine and primary care Controlled trial quality: uncertain

80. Role of mannose binding lectin in response to candida antigen immunotherapy of warts. (Abstract)

Role of mannose binding lectin in response to candida antigen immunotherapy of warts. Background: Warts is the commonest cutaneous manifestation of human papillomavirus (HPV) infection. Intralesional Candida antigen immunotherapy is used for wart treatment. Aim: To identify the role of mannose binding lectin (MBL) in susceptibility to HPV infection and to explore the relationship between MBL and response to intralesional Candida antigen immunotherapy of wart. Patients and methods: A case (...) -control study was enrolled with 96 participants; 48 wart cases and 48 healthy controls. MBL serum level assay baseline and after six settings of intralesional candida antigen injection was done by ELISA technique. MBL2 gene exon 1 codon 54 polymorphism was detected by using restriction fragment length polymorphism-polymerase chain reaction (RFLP-PCR). Results: A statistically significant difference in MBL serum level between wart cases and controls was found. An association between MBL2 exon1 codon 54

2019 Journal of Dermatological Treatment

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