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Wart Treatment

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41. Intralesional immunotherapy compared to cryotherapy in the treatment of warts. (Abstract)

Intralesional immunotherapy compared to cryotherapy in the treatment of warts. Warts are the most common clinical manifestation of the human papilloma-virus infection in the skin and mucous membranes. In spite of the various therapeutic modalities for nongenital skin warts, there is still no single method to be used as an approved treatment. In this study, we compared the efficacy of immunotherapy and cryotherapy on wart lesions.Sixty patients with verruca vulgaris and plantar warts were (...) . Immunotherapy was well-tolerated except for the pain during injection that was the most common side effect.Intralesional immunotherapy is an effective treatment of warts. This method has a better therapeutic response, needs fewer sessions, and is capable of treating distant warts.© 2017 The International Society of Dermatology.

2017 International Journal of Dermatology Controlled trial quality: uncertain

42. An expert system for selecting wart treatment method. (Abstract)

An expert system for selecting wart treatment method. As benign tumors, warts are made through the mediation of Human Papillomavirus (HPV) and may grow on all parts of body, especially hands and feet. There are several treatment methods for this illness. However, none of them can heal all patients. Consequently, physicians are looking for more effective and customized treatments for each patient. They are endeavoring to discover which treatments have better impacts on a particular patient (...) . The aim of this study is to identify the appropriate treatment for two common types of warts (plantar and common) and to predict the responses of two of the best methods (immunotherapy and cryotherapy) to the treatment. As an original work, the study was conducted on 180 patients, with plantar and common warts, who had referred to the dermatology clinic of Ghaem Hospital, Mashhad, Iran. In this study, 90 patients were treated by cryotherapy method with liquid nitrogen and 90 patients

2017 Computers in biology and medicine Controlled trial quality: uncertain

43. Efficacy and Safety of Three Cryotherapy Devices for Wart Treatment: A Randomized, Controlled, Investigator-Blinded, Comparative Study Full Text available with Trip Pro

Efficacy and Safety of Three Cryotherapy Devices for Wart Treatment: A Randomized, Controlled, Investigator-Blinded, Comparative Study Cutaneous warts are common skin lesions, caused by human papillomavirus. For years, liquid nitrogen is the cryogen of choice for wart treatment. Alternatively, several cryogenic devices for home treatment are commercially available. The present trial assessed efficacy and safety of a novel nitrous oxide-based cryogenic device for home use (EndWarts Freeze® (...) in Europe, Compound W® Nitro-Freeze in the USA).This investigator-blinded, controlled, randomized study compared the nitrous oxide device (test product) with a dimethylether propane-based product (Wartner®; comparator 1). Subjects with common or plantar warts (50/50 ratio) were randomized into two groups (n = 58, test product; n = 40, comparator 1). Sequentially, an extra treatment arm (n = 40) was added to compare with a dimethylether-based product with metal nib (Wortie®; comparator 2). Main objective

2017 Dermatology and therapy Controlled trial quality: uncertain

44. Topical ionic contra viral therapy comprised of digoxin and furosemide as a potential novel treatment approach for common warts. Full Text available with Trip Pro

Topical ionic contra viral therapy comprised of digoxin and furosemide as a potential novel treatment approach for common warts. DNA viruses such as HPV rely on K+ influx for replication. Both digoxin and furosemide inhibit the K+ influx by interacting with cell membrane ion co-transporters (Na+ /K+ -ATPase and Na+ -K+ -2Cl- co-transporter-1, respectively). We therefore hypothesized that these two compounds in a topical formulation may be valuable in the treatment of HPV-induced warts. This new (...) for 7 consecutive days on their lower back to assess safety and systemic exposure. Two warts were treated with 10 mg each and two served as negative controls to obtain preliminary evidence of treatment effect.ICVT was well tolerated topically, and there was no evidence of systemic exposure of digoxin or furosemide. There were no clinical relevant safety findings and no serious adverse events (SAEs). A rapid and statistically significant reduction in diameter, height and volume of the warts

2017 Journal of the European Academy of Dermatology and Venereology

45. Evaluation of the efficacy and safety of oral isotretinoin versus topical isotretinoin in the treatment of plane warts: a randomized open trial. (Abstract)

Evaluation of the efficacy and safety of oral isotretinoin versus topical isotretinoin in the treatment of plane warts: a randomized open trial. Plane warts are a common therapeutic problem. Our aim was to assess the efficacy and safety of oral versus topical isotretinoin in the treatment of plane warts.Forty patients with multiple plane warts were randomized into two groups. Group A was treated with oral isotretinoin capsules in the dose of 0.5 mg/kg/d and Group B with topical isotretinoin (...) 0.05% in gel formulation once daily at night. Treatment was given to the patients for 3 months or until the complete clearance of lesions, whichever was earlier. Patients with complete response were followed up monthly for 4 months to record the relapse rate.Results were analyzed in 16 patients of Group A and 13 patients of Group B. At the end of 3 months of therapy, 11 (69%) patients in Group A had complete remission whereas five (31%) had partial remission. In Group B, at the end of study, five

2017 International Journal of Dermatology Controlled trial quality: uncertain

46. Reply to "Topical ionic contra-viral therapy comprised of digoxin and furosemide as a potential novel treatment approach for common warts". (Abstract)

Reply to "Topical ionic contra-viral therapy comprised of digoxin and furosemide as a potential novel treatment approach for common warts". 29055137 2018 03 25 1468-3083 32 4 2018 Apr Journal of the European Academy of Dermatology and Venereology : JEADV J Eur Acad Dermatol Venereol Reply to 'Topical ionic contra-viral therapy comprised of digoxin and furosemide as a potential novel treatment approach for common warts'. e156-e157 10.1111/jdv.14645 Abdelmaksoud A A Mansoura Dermatology

2017 Journal of the European Academy of Dermatology and Venereology

47. Reply to correspondence 'Topical ionic contra viral therapy comprised of digoxin and furosemide as a potential novel treatment approach for common warts'. (Abstract)

Reply to correspondence 'Topical ionic contra viral therapy comprised of digoxin and furosemide as a potential novel treatment approach for common warts'. 29057503 2018 03 25 1468-3083 32 4 2018 Apr Journal of the European Academy of Dermatology and Venereology : JEADV J Eur Acad Dermatol Venereol Reply to correspondence 'Topical ionic contra-viral therapy comprised of digoxin and furosemide as a potential novel treatment approach for common warts '. e156 10.1111/jdv.14643 van der Kolk T T

2017 Journal of the European Academy of Dermatology and Venereology

48. An exploratory, prospective, open-label trial of ingenol mebutate gel 0.05% for the treatment of external anogenital warts. (Abstract)

An exploratory, prospective, open-label trial of ingenol mebutate gel 0.05% for the treatment of external anogenital warts. Anogenital warts (AGW) can cause physical discomfort and decreased quality of life. Recent case reports suggest that ingenol mebutate gel might be an effective treatment of AGW.To explore primarily the safety, and secondarily the efficacy of ingenol mebutate gel 0.05% in patients with AGW.This was an exploratory, open-label, 1-arm trial of ingenol mebutate gel 0.05 (...) % administered up to three times to patients with AGW. Safety was assessed by occurrence and severity of local skin reactions (LSRs) and treatment-related adverse events (AEs). Efficacy was assessed by complete clearance and reduction in AGW count 14 days after last treatment, and recurrence 12 weeks after clearance.Of 41 patients enrolled, 40 received treatment and 26 completed the trial. Patients had a median AGW count of 11.0 and AGW duration of 3.0 years at baseline. All patients experienced transient

2017 Journal of the European Academy of Dermatology and Venereology

49. Nonavalent human papillomavirus vaccination as a treatment for warts in an immunosuppressed adult Full Text available with Trip Pro

Nonavalent human papillomavirus vaccination as a treatment for warts in an immunosuppressed adult 28795126 2019 02 26 2352-5126 3 4 2017 Jul JAAD case reports JAAD Case Rep Nonavalent human papillomavirus vaccination as a treatment for warts in an immunosuppressed adult. 367-369 10.1016/j.jdcr.2017.05.007 Ferguson Sara B SB Penn State Hershey Medical Group, State College, Pennsylvania. Gallo Elisa S ES Dermatology Associates of Highland Park, Highland Park, Illinois. eng Case Reports 2017 07 26 (...) United States JAAD Case Rep 101665210 2352-5126 HPV, Human papillomavirus human papillomavirus immunosuppressed vaccine wart 2017 8 11 6 0 2017 8 11 6 0 2017 8 11 6 1 epublish 28795126 10.1016/j.jdcr.2017.05.007 S2352-5126(17)30110-8 PMC5537385 Arch Dermatol. 2010 May;146(5):475-7 20479293 Gynecol Oncol. 2007 Nov;107(2 Suppl 1):S31-3 18499916 J Am Acad Dermatol. 2012 Aug;67(2):e73-4 22794819 Acta Derm Venereol. 2015 Nov;95(8):1017-9 25824471 Infect Agent Cancer. 2014 Sep 01;9:29 25206925 JAMA

2017 JAAD Case Reports

50. The Successful Use of a Novel Microwave Device in the Treatment of a Plantar Wart Full Text available with Trip Pro

The Successful Use of a Novel Microwave Device in the Treatment of a Plantar Wart Plantar warts, caused by the human papilloma virus (HPV), are a commonly encountered condition presenting in clinic. In adults, an array of various therapies exists, frequently with modest results particularly with plantar lesions. Microwaves have had limited uses for medical purposes. Recently a new portable microwave device has been approved for the treatment of skin lesions. Prior research has demonstrated (...) immuno-stimulatory effects against HPV infection. We report the application of a novel portable medical microwave unit to treat a long-standing plantar wart which had failed to respond to other treatment modalities.

2017 Case reports in dermatology

51. Immune Modulation and Treatment of Human Papilloma Virus-Related Warts with Energetics of Living Systems Acupuncture Full Text available with Trip Pro

Immune Modulation and Treatment of Human Papilloma Virus-Related Warts with Energetics of Living Systems Acupuncture Background: Cutaneous warts are small skin lesions formed as a result of infection by the human papilloma virus (HPV). In the lesion, viral manipulation creates a microenvironment that favors virus survival and reproduction. Most lesions eventually regress, probably as a result of a Th1-mediated immune response. However, some warts fail to regress and become persistent. Objective (...) : The efficacy of treatment of persistent HPV-caused warts with Energetics of Living Systems acupuncture and monitored immune system involvement was tested. Methods: Eighteen patients with persistent warts were recruited for the study; 9 received acupuncture treatment and 9 received placebo. Each patient was treated 4 times. Results: Clinical success was defined as total clearance of all lesions with no recurrence for 3 months. In the treatment group, clinical success was 36.6% versus 0% in the placebo group

2017 Medical Acupuncture Controlled trial quality: uncertain

52. Real versus sham proximal biofield therapy in the treatment of warts of the hands and feet in adults: study protocol for a randomized controlled trial (MAGNETIK study) Full Text available with Trip Pro

Real versus sham proximal biofield therapy in the treatment of warts of the hands and feet in adults: study protocol for a randomized controlled trial (MAGNETIK study) Despite the lack of scientific studies on biofield therapies, they are widely acclaimed by patients. The mechanisms of action are not explained by current allopathic medical approaches. Warts are common and contagious viral lesions that may be refractory to standard dermatologic treatments such as cryotherapy, laser therapy (...) , and keratolytic ointments. Biofield therapies are efficient in various pathologies. Their ability to treat warts has never been demonstrated in a scientific study with a robust methodology. Patients with refractory warts often place their trust in these alternative therapies because of the poor results obtained from traditional medicine. We propose a prospective, randomized, single-blind, assessor-blind trial to evaluate the efficacy of treatment of warts by biofield therapy.Subjects with warts on their feet

2017 Trials Controlled trial quality: predicted high

53. Controlling Human Papilloma Virus: A Public Health Perspective of Treatment of Anogenital Warts Full Text available with Trip Pro

Controlling Human Papilloma Virus: A Public Health Perspective of Treatment of Anogenital Warts 28377465 2018 09 27 2018 11 13 1549-490X 22 5 2017 05 The oncologist Oncologist Controlling Human Papilloma Virus: A Public Health Perspective of Treatment of Anogenital Warts. 495-496 10.1634/theoncologist.2016-0379 Tanveer Nadeem N Department of Pathology, University College of Medical Sciences, University of Delhi, Delhi, India ntobh104@yahoo.co.in. eng Journal Article 2017 04 04 United States

2017 The oncologist

54. Successful treatment of plantar warts with intralesional bleomycin and electroporation: pilot prospective study Full Text available with Trip Pro

Successful treatment of plantar warts with intralesional bleomycin and electroporation: pilot prospective study Numerous studies have been performed to evaluate the efficacy of intralesional bleomycin for the treatment of warts with inconsistent result. Nevertheless, it is well known that the cytotoxicity of bleomycin can be enhanced in vivo by 300 to 700-fold by electroporation.In this article, we present an interventional, one-center, prospective case series, clinical trial (...) of the effectiveness of intralesional bleomycin combined with electroporation for the treatment of plantar warts, in comparison to the use of intralesional bleomycin alone.The study's cohort included 12 men and 10 women, with a mean age of 53.8 years. A total of 22 warts were treated. In dividing the patients in two groups (complete remission against all the others) and analyzing the different outcomes in the two arms of patients, a statistical significant difference was found (p=0.0015), proving a greater

2017 Dermatology practical & conceptual

55. Topical treatments for external genital warts in non-immunocompromised patients: a systematic review and network meta-analysis

Topical treatments for external genital warts in non-immunocompromised patients: a systematic review and network meta-analysis Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration record, any (...) , this assumption is unlikely to hold true for data from animal studies, which generally include various species, strains and treatment regimes, for which different true effects are likely to exist. The random-effects model takes into account both the within-study (sampling error) and between-study (differences in the true effect size) variance. Should the excessive between-study variance be very low or zero, the random-effects model will yield the same results as the fixed-effect model. For further details

2019 PROSPERO

56. Clinical Study : Efficacy and Safety of Three Cryotherapy Devices for Wart Treatment

Clinical Study : Efficacy and Safety of Three Cryotherapy Devices for Wart Treatment Clinical Study : Efficacy and Safety of Three Cryotherapy Devices for Wart Treatment - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before (...) adding more. Clinical Study : Efficacy and Safety of Three Cryotherapy Devices for Wart Treatment The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT03129373 Recruitment Status : Completed First Posted : April 26, 2017 Last Update Posted : September 19, 2017 Sponsor: Oystershell NV Information provided

2017 Clinical Trials

57. A Trial of a Botanical Drug Containing East Indian Sandalwood Oil (EISO) for the Treatment of External Genital Warts

A Trial of a Botanical Drug Containing East Indian Sandalwood Oil (EISO) for the Treatment of External Genital Warts A Trial of a Botanical Drug Containing East Indian Sandalwood Oil (EISO) for the Treatment of External Genital Warts - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number (...) of saved studies (100). Please remove one or more studies before adding more. A Trial of a Botanical Drug Containing East Indian Sandalwood Oil (EISO) for the Treatment of External Genital Warts The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details

2017 Clinical Trials

58. Intralesional Candidal Antigen Versus Intralesional Zinc Sulphate in Treatment of Cutaneous Warts

Intralesional Candidal Antigen Versus Intralesional Zinc Sulphate in Treatment of Cutaneous Warts Intralesional Candidal Antigen Versus Intralesional Zinc Sulphate in Treatment of Cutaneous Warts - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove (...) one or more studies before adding more. Intralesional Candidal Antigen Versus Intralesional Zinc Sulphate in Treatment of Cutaneous Warts The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03158168 Recruitment Status

2017 Clinical Trials

59. Intralesional Measles, Mumps, Rubella (MMR) Vaccine Versus Cryotherapy in Treatment of Multiple Common and Planter Warts

Intralesional Measles, Mumps, Rubella (MMR) Vaccine Versus Cryotherapy in Treatment of Multiple Common and Planter Warts Intralesional Measles, Mumps, Rubella (MMR) Vaccine Versus Cryotherapy in Treatment of Multiple Common and Planter Warts - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum (...) number of saved studies (100). Please remove one or more studies before adding more. Intralesional Measles, Mumps, Rubella (MMR) Vaccine Versus Cryotherapy in Treatment of Multiple Common and Planter Warts The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details

2017 Clinical Trials

60. Carbon Dioxide Laser and Cryotherapy in Treatment of Warts

Carbon Dioxide Laser and Cryotherapy in Treatment of Warts Carbon Dioxide Laser and Cryotherapy in Treatment of Warts - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Carbon Dioxide Laser and Cryotherapy (...) in Treatment of Warts The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03166137 Recruitment Status : Not yet recruiting First Posted : May 25, 2017 Last Update Posted : May 25, 2017 See Sponsor: Assiut University Information

2017 Clinical Trials

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