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Wart Treatment

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181. Treatment of External Genital Warts With Cryotherapy and Sinecatechins 15% Ointment

Treatment of External Genital Warts With Cryotherapy and Sinecatechins 15% Ointment Treatment of External Genital Warts With Cryotherapy and Sinecatechins 15% Ointment - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before (...) adding more. Treatment of External Genital Warts With Cryotherapy and Sinecatechins 15% Ointment The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02147353 Recruitment Status : Completed First Posted : May 26, 2014 Last Update Posted : July 10, 2015 Sponsor: Icahn School of Medicine at Mount Sinai

2014 Clinical Trials

182. Subcutaneous intralesional Ksharodaka injection: A novel treatment for the management of Warts: A case series (PubMed)

Subcutaneous intralesional Ksharodaka injection: A novel treatment for the management of Warts: A case series Warts are generally managed using cryosurgery, keratolytic ointments, curettage and electrodessication. Warts, vis-a-vis Charmakila, in Ayurvedic classical texts are classified into different types depending on the dominance of dosha. Ayurveda prescribes oral medications, topical use of Kshara (alkaline ash of herbs), Agni (thermal cautery) and Shastrakarma (surgery) for removal (...) of Charmakila. Use of topical Kshara in the form of powder, aqueous solution i.e. Ksharodaka and Ksharasutra (thread smeared with Kshara) for warts has been reported. However, these methods necessitate multiple sittings and takea longer duration for removal of the warts. Herewith, we report a case series of different types of warts treated with intralesional infiltration of Apamarga Ksharodaka (AK), i.e. aqueous solution of Apamarga (Achyranthes aspera) Kshara. We observed that all these warts took

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2014 Journal of Ayurveda and integrative medicine

183. Efficacy, safety and tolerability of green tea catechins in the treatment of external anogenital warts: a systematic review and meta-analysis.

Efficacy, safety and tolerability of green tea catechins in the treatment of external anogenital warts: a systematic review and meta-analysis. External anogenital warts (EGWs) are non-malignant skin tumours caused by human papillomavirus. They are one of the fastest growing sexually transmitted diseases. Current treatments are unsatisfactory. Green tea sinecatechin Polyphenon E ointment is a botanical extract from green tea leaves exhibiting anti-oxidant, anti-viral and anti-tumour (...) evaluating efficacy and safety of Polyphenon E 15% and 10% in the treatment of warts were included in the systematic review and meta-analysis. A total of 660 men and 587 women were enrolled. Regarding primary outcome, both Polyphenon E 15% and 10% demonstrated significantly higher likelihood of complete clearance of baseline and baseline and new warts compared with controls. No significant heterogeneity was detected. Recurrence rates were very low. Commonest local skin sign was erythema and local skin

2014 Journal of the European Academy of Dermatology and Venereology : JEADV

184. Comparison of efficacy of 5% potassium hydroxide solution versus cryotherapy in the treatment of male genital wart: a randomized clinical trial. (PubMed)

Comparison of efficacy of 5% potassium hydroxide solution versus cryotherapy in the treatment of male genital wart: a randomized clinical trial. 24566576 2014 06 02 2014 09 26 0392-0488 149 1 2014 Feb Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia G Ital Dermatol Venereol Comparison of efficacy of 5% potassium hydroxide solution versus cryotherapy in the treatment of male genital wart: a randomized clinical trial. 149-50

2014 Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia Controlled trial quality: uncertain

185. Efficacy of Myrtus communis L. and Descurainia sophia L. Versus Salicylic Acid for Wart Treatment (PubMed)

Efficacy of Myrtus communis L. and Descurainia sophia L. Versus Salicylic Acid for Wart Treatment Wart is a skin disease with circular appendages, which is called "suloul" in Iranian traditional medicine (ITM). According to ITM literature, warts have different types and causes. The most important mechanism is excretion of materials (Khelt) from body to skin and mucus; its causative material is often phlegm, black bile or a combination of them. To treat warts, it is necessary to consider (...) groups (P < 0.001). Relapse was not seen in any groups after three months. The frequency of side effects was similar after three months.M. communis L. can be used as a topical treatment for warts. It not only shows more rapid response than salicylic acid, but also has fewer side effects. It seems that D. sophia L. can modify the digestion process and patients can excrete large amounts of the substance that causes warts. Therefore, it is better to use it more than 40 days. According to our

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2014 Iranian Red Crescent medical journal Controlled trial quality: uncertain

186. A comparison of a 5% potassium hydroxide solution with a 5-fluorouracil and salicylic acid combination in the treatment of patients with anogenital warts: a randomized, open-label clinical trial. (PubMed)

A comparison of a 5% potassium hydroxide solution with a 5-fluorouracil and salicylic acid combination in the treatment of patients with anogenital warts: a randomized, open-label clinical trial. Anogenital warts are caused by human papillomavirus (HPV), over 30 types of which are infectious for the anogenital tract. Without treatment, warts may regress spontaneously, remain unchanged, or increase in number and size. This study compared the efficacy of a topical 5% potassium hydroxide (KOH (...) ) solution with that of a topical 0.5% 5-fluorouracil (5-FU) and 10% salicylic acid (SA) combination in the treatment of anogenital warts. Sixty patients were randomly assigned to receive topical KOH or 5-FU + SA. Both groups demonstrated a significant decrease in numbers of lesions (P < 0.05), but this difference was not significant at week 12 (P > 0.05). The mean number of lesions decreased from baseline to week 12 from 17.03 ± 12.64 to 3.73 ± 7.30 and from 16.13 ± 12.97 to 3.10 ± 4.90 in the KOH and 5

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2014 International journal of dermatology Controlled trial quality: uncertain

187. Needling Versus Liquid Nitrogen Cryotherapy for the Treatment of Pedal Warts A Randomized Controlled Pilot Study. (PubMed)

Needling Versus Liquid Nitrogen Cryotherapy for the Treatment of Pedal Warts A Randomized Controlled Pilot Study. We hypothesized that needling of a pedal wart creates local inflammation and a subsequent cell-mediated immune response (CMIR) against human papillomavirus. The primary objective of this study was to investigate whether needling to induce a CMIR against human papillomavirus is an effective treatment for pedal warts compared with liquid nitrogen cryotherapy. A secondary objective (...) was to investigate whether the CMIR induced by needling is effective against satellite pedal warts.Eligible patients with pedal warts were randomly allocated to receive either needling or liquid nitrogen cryotherapy. Only the primary pedal wart was treated during the study. Follow-up was 12 weeks, with outcome assessments made independently under blinded circumstances.Of 37 patients enrolled in the study, 18 were allocated to receive needling and 19 to receive liquid nitrogen cryotherapy. Regression

2014 Journal of the American Podiatric Medical Association Controlled trial quality: uncertain

188. Efficacy of combination therapy of oral zinc sulfate with imiquimod, podophyllin or cryotherapy in the treatment of vulvar warts. (PubMed)

Efficacy of combination therapy of oral zinc sulfate with imiquimod, podophyllin or cryotherapy in the treatment of vulvar warts. Zinc sulfate is beneficial in the treatment of epithelial warts. We conducted this study to compare the efficacy of combination therapy of oral zinc sulfate with conventional treatments in the treatment of vulvar warts.This study was a randomized controlled trial. The sample size was 42 in each group. Women aged 20-50 years were placed by the block randomized method (...) in the podophyllin-, imiquimod- and cryotherapy-treated patients compared to patients receiving these treatments in combination with oral zinc sulfate (P<0.05).Combined therapy of oral zinc sulfate with conventional treatments of vulvar warts appears to reduce the relapse rate.© 2014 The Authors. Journal of Obstetrics and Gynaecology Research © 2014 Japan Society of Obstetrics and Gynecology.

2014 The journal of obstetrics and gynaecology research Controlled trial quality: uncertain

189. Needling versus liquid nitrogen cryotherapy for the treatment of pedal warts: A randomised controlled trial pilot study. (PubMed)

Needling versus liquid nitrogen cryotherapy for the treatment of pedal warts: A randomised controlled trial pilot study. Abstract Background: The hypothesis of this study was that needling of a pedal wart would create local inflammation and a subsequent cell-mediated immune response against human papillomavirus. The primary objective of this study was to investigate if needling to induce a cell-mediated immune response against human papillomavirus is an effective treatment of pedal warts (...) in comparison to liquid nitrogen cryotherapy. A secondary objective of this study was to investigate if the cell-mediated immune response induced by needling is effective against satellite pedal warts. Methods: Eligible participants presenting to the University of Western Australia Podiatry Clinic with pedal wart/s were randomly allocated to treatment - either needling or liquid nitrogen cryotherapy. Only the primary pedal wart was treated during the study. Participant follow-up was twelve weeks

2014 Journal of the American Podiatric Medical Association Controlled trial quality: uncertain

190. A prospective, open, comparative study of 5% potassium hydroxide solution versus cryotherapy in the treatment of genital warts in men. (PubMed)

A prospective, open, comparative study of 5% potassium hydroxide solution versus cryotherapy in the treatment of genital warts in men. Genital warts are caused by human papillomavirus infection and represent one of the most common sexually transmitted diseases. Many infections are transient but the virus may recur, persist, or become latent. To date, there is no effective antiviral treatment to eliminate HPV infection and most therapies are aimed at the destruction of visible lesions. Potassium (...) hydroxide is a strong alkali that has been shown to be safe and effective for the treatment of genital warts and molluscum contagiosum. Cryotherapy is considered one of the most established treatments for genital warts. No comparative trials have been reported to date on the use of potassium hydroxide for genital warts.A prospective, open-label, randomized clinical trial was conducted to compare topical potassium hydroxide versus cryotherapy in the treatment of genital warts affecting immunocompetent

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2014 Anais brasileiros de dermatologia Controlled trial quality: uncertain

191. A randomized trial of efficacy of beta-sitosterol and its glucoside as adjuvant to cryotherapy in the treatment of anogenital warts. (PubMed)

A randomized trial of efficacy of beta-sitosterol and its glucoside as adjuvant to cryotherapy in the treatment of anogenital warts. All available treatments for anogenital warts have substantial failure rates. An immunomodulating treatment that enhances the patient's own immunity could be valuable as an adjuvant to conventional methods.About 123 patients were enrolled in this study and were randomized either to undergo only cryotherapy every 3 weeks (n = 60 patients) or to undergo cryotherapy (...) and to receive a mixture containing 20 mg sterol and 0.2 mg sterolin (BSS-BSSG mixture), known for its immunomodulating properties (n = 63).A complete response after 3 months was demonstrated by 18.3% of the patients in the first group and 30.2% of the second group, while 61.7% of the first group and 79.4% of the second group were lesion free at the end of the 6-month follow-up period. Cox regression analysis of the time until response showed a significant advantage to the mixture treatment group (hazard

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2014 Journal of Dermatological Treatment Controlled trial quality: uncertain

192. A double-blind, randomized, placebo-controlled trial of oral isotretinoin in the treatment of recalcitrant facial flat warts. (PubMed)

A double-blind, randomized, placebo-controlled trial of oral isotretinoin in the treatment of recalcitrant facial flat warts. Abstract Background: Recalcitrant facial flat warts are caused by human papillomavirus and may persist for years despite treatment. Isotretinoin has demonstrated benefits in the treatment of recalcitrant, genital and common warts, but placebo-controlled trials have not been performed.To determine whether isotretinoin is safe and effective for recalcitrant facial flat (...) of the study is a lack of follow-up to assess for recurrence after the drug was discontinued.Isotretinoin is an effective treatment for recalcitrant flat facial warts with a well-known, manageable safety profile.

2014 Journal of Dermatological Treatment Controlled trial quality: predicted high

193. Cryotherapy versus salicylic acid for the treatment of plantar warts (verrucae): a randomised controlled trial. (PubMed)

Cryotherapy versus salicylic acid for the treatment of plantar warts (verrucae): a randomised controlled trial. To compare the clinical effectiveness of cryotherapy versus salicylic acid for the treatment of plantar warts.A multicentre, open, two arm randomised controlled trial.University podiatry school clinics, NHS podiatry clinics, and primary care in England, Scotland, and Ireland.240 patients aged 12 years and over, with a plantar wart that in the opinion of the healthcare professional (...) was suitable for treatment with both cryotherapy and salicylic acid.Cryotherapy with liquid nitrogen delivered by a healthcare professional, up to four treatments two to three weeks apart. Patient self treatment with 50% salicylic acid (Verrugon) daily up to a maximum of eight weeks.Complete clearance of all plantar warts at 12 weeks. Secondary outcomes were (a) complete clearance of all plantar warts at 12 weeks controlling for age, whether the wart had been treated previously, and type of wart, (b

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2011 BMJ Controlled trial quality: predicted high

194. Warts, Genital (Treatment)

Warts, Genital (Treatment) Human Papillomavirus (HPV) Treatment & Management: Approach Considerations, Considerations in Specific Patient Subgroups, Pharmacologic Therapy Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache (...) =aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMjE5MTEwLXRyZWF0bWVudA== processing > Human Papillomavirus (HPV) Treatment & Management Updated: Feb 05, 2019 Author: Peter A Gearhart, MD; Chief Editor: Pranatharthi Haran Chandrasekar, MBBS, MD Share Email Print Feedback Close Sections Sections Human Papillomavirus (HPV) Treatment Approach Considerations There is no single curative treatment for condylomata acuminata. [ ] Eradication or reduction of symptoms is the primary goal of treating warts, but elimination of dysplastic lesions is the goal in treating

2014 eMedicine.com

195. Warts, Nongenital (Treatment)

Warts, Nongenital (Treatment) Nongenital Warts Treatment & Management: Medical Care, Surgical Care Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTEzMzMxNy10cmVhdG1lbnQ= processing > Nongenital Warts Treatment (...) & Management Updated: Jun 05, 2018 Author: Philip D Shenefelt, MD, MS; Chief Editor: William D James, MD Share Email Print Feedback Close Sections Sections Nongenital Warts Treatment Medical Care Multiple modalities are available for the treatment of warts, but none is uniformly effective. [ , ] Start with the least painful, least expensive, and least time-consuming methods. Reserve the more expensive and invasive procedures for refractory extensive warts. Immunosuppressed individuals often are refractory

2014 eMedicine.com

196. Urethral Warts (Treatment)

Urethral Warts (Treatment) Urethral Warts: Overview, Epidemiology, HPV Transmission Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvNDQzMDA2LW92ZXJ2aWV3 processing > Urethral Warts Updated: Oct 19, 2018 Author (...) with the development of genital tract and anal cancers. [ ] Immunosuppression is associated with reactivation of HPV, increasing the risk of malignant transformation. Patients at risk of developing malignancies may benefit from therapy aimed at eradicating genital warts. [ , , , ] However, medical treatments aimed at treating urethral warts should generally be used with caution, and they should be used only when the warts are easily accessible, as in the fossa navicularis. Podophyllin is contraindicated during

2014 eMedicine.com

197. Warts, Genital (Treatment)

Warts, Genital (Treatment) Genital Warts Treatment & Management: Approach Considerations, Consultations, Prevention Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvNzYzMDE0LXRyZWF0bWVudA== processing > Genital (...) Warts Treatment & Management Updated: Oct 16, 2018 Author: Delaram Ghadishah, MD; Chief Editor: William D James, MD Share Email Print Feedback Close Sections Sections Genital Warts Treatment Approach Considerations Symptomatic treatment may be warranted in emergency situations. Use pressure to stop bleeding, if present. Relieve urethral obstruction (rare). Search for evidence of coexistent STDs; treat them if found and indicated. Further treatment, screening, and vaccination guidelines from

2014 eMedicine Emergency Medicine

198. Warts, Plantar (Treatment)

Warts, Plantar (Treatment) Nongenital Warts Treatment & Management: Medical Care, Surgical Care Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTEzMzMxNy10cmVhdG1lbnQ= processing > Nongenital Warts Treatment (...) & Management Updated: Jun 05, 2018 Author: Philip D Shenefelt, MD, MS; Chief Editor: William D James, MD Share Email Print Feedback Close Sections Sections Nongenital Warts Treatment Medical Care Multiple modalities are available for the treatment of warts, but none is uniformly effective. [ , ] Start with the least painful, least expensive, and least time-consuming methods. Reserve the more expensive and invasive procedures for refractory extensive warts. Immunosuppressed individuals often are refractory

2014 eMedicine Emergency Medicine

199. Intralesional immunotherapy in treatment of warts, a systematic review and meta-analysis

Intralesional immunotherapy in treatment of warts, a systematic review and meta-analysis Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email salutation (e.g. "Dr Smith" or "Joanne") for correspondence: Organisation web address: Timing (...) is the typical model of choice for pre-clinical meta-analyses. This is because in the fixed-effect model, it is assumed that the differences in observed effect between studies is solely due to sampling error (i.e. differences in sample size), and that the true effect is the same (fixed) across all studies. However, this assumption is unlikely to hold true for data from animal studies, which generally include various species, strains and treatment regimes, for which different true effects are likely to exist

2017 PROSPERO

200. Warts and verrucae

and neck). Plantar warts (verrucae) grow on the soles of the feet, often have dark dots in the centre, and may be painful. Mosaic warts occur when palmar or plantar warts coalesce into larger plaques on the hands and feet. Although warts can be cosmetically unsightly, they are not harmful, usually do not cause symptoms, and most resolve without treatment. Advice should be offered on reducing the risk of transmission and limiting personal spread of warts. Treatment should be considered if a wart (...) is painful, cosmetically unsightly, persistent, or the person requests treatment. For the treatment of other warts in adults and older children, options are topical salicylic acid, cryotherapy, or a combination of both (cryotherapy is not recommended for younger children). Warts can generally be managed in primary care, but referral to a dermatologist is necessary if the person has: An uncertain diagnosis. A facial wart. Multiple recalcitrant warts and compromised immunity. Extensive warts. Persistent

2014 NICE Clinical Knowledge Summaries

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