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Wart Immune Therapy

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61. Warts, Plantar (Follow-up)

), and diphencyclopropenone (DCP) are contact sensitizers. Trichloroacetic acid is a caustic compound that causes tissue necrosis. Podophyllin is a cytotoxic compound used more commonly in the treatment of genital warts. Aminolevulinic acid (ALA) is a photosensitizer that has been successfully used topically in combination with blue light to treat flat warts. [ ] Several prescription medications have proven beneficial in treating warts. These can be applied at home by the patient. Imiquimod is an immune response modifier (...) DNA in the plume of erbium:YAG laser-treated warts. J Am Acad Dermatol . 1998 Mar. 38(3):426-8. . Rivera A, Tyring SK. Therapy of cutaneous human Papillomavirus infections. Dermatol Ther . 2004. 17(6):441-8. . Media Gallery Plantar warts. Common wart on the hand. of 2 Tables Contributor Information and Disclosures Author Philip D Shenefelt, MD, MS Professor, Department of Dermatology and Cutaneous Surgery, University of South Florida College of Medicine; Past Chief, Section of Dermatology, James

2014 eMedicine Emergency Medicine

62. Warts, Genital (Follow-up)

is delivered to the affected lesions, causing tissue coagulation and necrosis. Treatment is successful in about 80% of cases. Immune-based therapy Physician administered treatments include acid applications (bichloroacetic acid or trichloroacetic acid) and interferon injections with antiviral mechanisms. Medications for home use include imiquimod 5% cream, podofilox gel or solution, and antiproliferative compounds (5-fluorouracil). Vaccination [ , ] The 9-valent HPV vaccine (Gardasil 9 [9vHPV (...) of Pediatric Emergency Medicine, Departments of Emergency Medicine and Pediatrics, Kings County Hospital Center Binita R Shah, MD, FAAP is a member of the following medical societies: Disclosure: Nothing to disclose. What would you like to print? What would you like to print? Sections Genital Warts Find Us On About Membership WebMD Network Editions All material on this website is protected by copyright, Copyright © 1994-2019 by WebMD LLC. This website also contains material copyrighted by 3rd parties

2014 eMedicine Emergency Medicine

63. Warts, Genital (Overview)

, Departments of Emergency Medicine and Pediatrics, Kings County Hospital Center Binita R Shah, MD, FAAP is a member of the following medical societies: Disclosure: Nothing to disclose. What would you like to print? What would you like to print? Sections Genital Warts Find Us On About Membership WebMD Network Editions All material on this website is protected by copyright, Copyright © 1994-2019 by WebMD LLC. This website also contains material copyrighted by 3rd parties. Close encoded search term (Genital (...) of external lesions on the genitalia. Previous Next: Patient Education Identify and educate persons at risk. For patient education resources, visit the . Also, see the patient education article . Previous References Diamantis ML, Bartlett BL, Tyring SK. Safety, efficacy & recurrence rates of imiquimod cream 5% for treatment of anogenital warts. Skin Therapy Lett . 2009 Jun. 14(5):1-3, 5. . [Guideline] American College of Obstetricians and Gynecologists (ACOG). Human papillomavirus. Washington (DC

2014 eMedicine Emergency Medicine

64. Warts, Genital (Diagnosis)

, Departments of Emergency Medicine and Pediatrics, Kings County Hospital Center Binita R Shah, MD, FAAP is a member of the following medical societies: Disclosure: Nothing to disclose. What would you like to print? What would you like to print? Sections Genital Warts Find Us On About Membership WebMD Network Editions All material on this website is protected by copyright, Copyright © 1994-2019 by WebMD LLC. This website also contains material copyrighted by 3rd parties. Close encoded search term (Genital (...) of external lesions on the genitalia. Previous Next: Patient Education Identify and educate persons at risk. For patient education resources, visit the . Also, see the patient education article . Previous References Diamantis ML, Bartlett BL, Tyring SK. Safety, efficacy & recurrence rates of imiquimod cream 5% for treatment of anogenital warts. Skin Therapy Lett . 2009 Jun. 14(5):1-3, 5. . [Guideline] American College of Obstetricians and Gynecologists (ACOG). Human papillomavirus. Washington (DC

2014 eMedicine Emergency Medicine

65. Safety Study of Multikine in the Treatment of Perianal Warts

in the Treatment of Perianal Warts The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02115919 Recruitment Status : Terminated (Unable to enroll prospective subject for dose escalation) First Posted : April 16, 2014 Last Update Posted : August 19, 2016 Sponsor: United States Naval Medical Center, San Diego (...) Collaborator: CEL-SCI Corporation Information provided by (Responsible Party): United States Naval Medical Center, San Diego Study Details Study Description Go to Brief Summary: Caused by the human papillomavirus (HPV), anogenital warts are a common sexually-transmitted infection (STI). They are distressing to those who have them and are a source of viral shedding and transmission to others. Treatment of warts is aimed at destruction of the lesion. Objectives: Establish safety of Multikine in treatment

2013 Clinical Trials

66. Oral Zinc Gluconate as Treatment for Recalcitrant Cutaneous Warts: A Randomized, Double-blind, Placebo-controlled Trial

Posted : February 4, 2013 Last Update Posted : November 14, 2013 Sponsor: Philippine Dermatological Society Information provided by (Responsible Party): Rochelle L. Castillo, Philippine Dermatological Society Study Details Study Description Go to Brief Summary: Up to one-third of common warts can remain recalcitrant, an occurrence that has been attributed to impaired cell-mediated immunity. At present, no guidelines exist for the management of recalcitrant cutaneous warts. Zinc, a well-established (...) in activity; no medical intervention/therapy required Grade 2, Moderate: Mild to moderate limitation in activity; no or minimal medical intervention required Grade 3, Severe: Marked limitation in activity; medical intervention required; hospitalization possible Grade 4, Life-Threatening: Extreme limitation in activity; significant medical intervention required; hospitalization or hospice care probable Recurrence [ Time Frame: 120 days ] The recurrence rate in patients who achieve complete response to zinc

2013 Clinical Trials

67. Declining Genital Warts in Young Women in England Associated With HPV 16/18 Vaccination: An Ecological Study. Full Text available with Trip Pro

Declining Genital Warts in Young Women in England Associated With HPV 16/18 Vaccination: An Ecological Study. Diagnoses of genital warts (GW) in genitourinary medicine (GUM) clinics have been increasing in England for many years. In 2008, an HPV immunization program began with a bivalent vaccine (Cervarix). This was expected to markedly reduce infections and disease due to human papillomavirus (HPV) 16/18 but not HPV 6/11 infections or disease. However, from 2009 to 2011 there were decreases (...) in reported diagnoses of GW in young females at GUM clinics.Using data from GUM clinics and a sample of general practices (GPs) throughout England, we analyzed rates of GW diagnoses by age, year of diagnosis, and estimated immunization coverage.The overall reduction in GW diagnoses at GUM clinics between 2008 and 2011 was 13.3% among 16- to 19-year-old females, with the greatest decline of 20.8% in 17-year-olds. Declines were positively associated with estimated immunization coverage. A similar pattern

2013 Journal of Infectious Diseases

68. Efficacy and Safety of SR-T100 Gel in Common Warts (CW) Patients

study. Patient had used any wart-removing product/modality in the treatment area within 30 days prior to the Randomization visit or received cryotherapy in the treatment area within 60 days prior to the Randomization visit. Patient who has immune-compromised conditions, have required or will require systemic intake of immunosuppressive or immunomodulatory medication (oral or parental corticosteroids are included) within 30 days prior to the Randomization visit or during the course of the study (...) : G&E Herbal Biotechnology Co., LTD Information provided by (Responsible Party): G&E Herbal Biotechnology Co., LTD Study Details Study Description Go to Brief Summary: This phase II study is to evaluate the efficacy of SR-T100 gel in complete clearance of target warts at different concentrations (1.0% and 2.3% of SM in Solanum undatum plant extract) in patients with CW. Condition or disease Intervention/treatment Phase Common Wart Drug: Vehicle gel Drug: SR-T100 gel with 1.0% of SM Drug: SR-T100

2013 Clinical Trials

69. Safety and Efficacy Study to Test Topical AS101 for External Genital Warts

Study Start Date : March 2012 Actual Primary Completion Date : July 2013 Actual Study Completion Date : July 2013 Resource links provided by the National Library of Medicine related topics: Arms and Interventions Go to Arm Intervention/treatment Experimental: Topical AS101 15% AS101 ointment applied twice a day for treatment of external genital warts. Drug: Topical AS101 AS101 15% ointment will be applied topically twice daily on external genital warts for up to 16 weeks. Outcome Measures Go (...) to Day 1 (patients on long-term suppressive antiviral therapy are eligible); Current and/or recurrent pathologically relevant genital infections other than genital warts; Diagnosis of high-grade cervical dysplasia; Internal anogenital, vaginal, urethral and cervical warts requiring treatment; Chronic or acute skin condition that might interfere with the evaluation of the treatment or study drug effect; Cutaneous surgery, including cryosurgery, to genital area within 30 days of Day 1; Screening

2012 Clinical Trials

70. A Comparative Study of Occlusive Heat Patch in the Treatment of Warts

warts with heat is the use of an occlusive patch that contains a mixture of chemicals (ferric chloride), which in the presence of oxygen reacts to generate reproducible thermal warming of the skin to a temperature of 42-43ºC for at least two hours. The heat is believed to alter the immune response and kill the HPV virus in the wart tissue. Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Actual Enrollment : 31 participants Intervention Model: Single (...) for the duration of the study. Exclusion Criteria: Subjects who are immunocompromised for any reason or are known to be HIV+ based on medical history taken at screening. Subjects taking any of the following systemic therapy with 4 weeks of enrollment; cimetidine, systemic steroids, immunomodulators or immunosuppressants. Subjects who have used any anti-verruca treatments within 4 weeks. These include but are not limited to topical salicylic acid preparations, imiquimod (Aldara), podophyllin containing

2012 Clinical Trials

71. Warts and all: Human papillomavirus in primary immunodeficiencies. Full Text available with Trip Pro

Warts and all: Human papillomavirus in primary immunodeficiencies. Infection with human papillomavirus (HPV) is almost universal and eventually asymptomatic, but pathologic infection with HPV is severe, recurrent, and recalcitrant to therapy. It is also an underappreciated manifestation of primary immunodeficiency. Mutations in EVER1, EVER2, GATA2, CXCR4, and dedicator of cytokinesis 8 (DOCK8) are typically associated with extensive HPV infections, whereas several other primary immune defects

2012 Journal of Allergy and Clinical Immunology

72. Throwing off warts. Full Text available with Trip Pro

Throwing off warts. 698552 1978 12 20 2018 11 13 0007-1447 2 6136 1978 Aug 19 British medical journal Br Med J Throwing off warts. 521-2 eng Editorial England Br Med J 0372673 0007-1447 0 Antibodies, Viral AIM IM Antibodies, Viral Humans Immunity, Cellular Skin Diseases immunology therapy Warts immunology therapy 1978 8 19 1978 8 19 0 1 1978 8 19 0 0 ppublish 698552 PMC1607013 Clin Exp Immunol. 1976 Dec;26(3):419-24 188577 Arch Dermatol. 1978 Feb;114(2):213-5 305230 Arch Dermatol. 1977 Sep;113

1978 British medical journal

73. Spectrum of myeloid neoplasms and immune deficiency associated with germline GATA2 mutations Full Text available with Trip Pro

Spectrum of myeloid neoplasms and immune deficiency associated with germline GATA2 mutations Guanine-adenine-thymine-adenine 2 (GATA2) mutated disorders include the recently described MonoMAC syndrome (Monocytopenia and Mycobacterium avium complex infections), DCML (dendritic cell, monocyte, and lymphocyte deficiency), familial MDS/AML (myelodysplastic syndrome/acute myeloid leukemia) (myeloid neoplasms), congenital neutropenia, congenital lymphedema (Emberger's syndrome), sensorineural (...) deafness, viral warts, and a spectrum of aggressive infections seen across all age groups. While considerable efforts have been made to identify the mutations that characterize this disorder, pathogenesis remains a work in progress with less than 100 patients described in current literature. Varying clinical presentations offer diagnostic challenges. Allogeneic stem cell transplant remains the treatment of choice. Morbidity, mortality, and social costs due to the familial nature of the disease

2015 Cancer medicine

74. Multicenter Trial Evaluating the Immunogenicity of HPV Vaccination in Girls on Immunosuppressive Therapy.

: 37 participants Allocation: Non-Randomized Intervention Model: Single Group Assignment Masking: None (Open Label) Official Title: Multicenter Clinical Trial Evaluating the Immunological Response of Vaccination Against Infection by Human Papillomavirus (HPV) 6, 11, 16, 18 in Girls Receiving Immunosuppressive Therapy. Study Start Date : October 2012 Actual Primary Completion Date : May 2015 Estimated Study Completion Date : November 2016 Resource links provided by the National Library of Medicine (...) Multicenter Trial Evaluating the Immunogenicity of HPV Vaccination in Girls on Immunosuppressive Therapy. Multicenter Trial Evaluating the Immunogenicity of HPV Vaccination in Girls on Immunosuppressive Therapy. - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100

2012 Clinical Trials

75. Complete Healing of a Giant Wart in a Severely Immune-Compromised Patient with HIV Infection Treated with Acupuncture Full Text available with Trip Pro

disease, who developed a monstrous wart covering the entirety of the radial district of his right hand. He was completely healed after a long treatment with traditional Chinese acupuncture, in spite of minimal immune recovery induced by efficacious antiretroviral therapy. To the best of our knowledge, therefore, the present report may be the first direct clinical evidence that acupuncture may be effective in the treatment of cutaneous warts also in HIV-infected patients. (...) Complete Healing of a Giant Wart in a Severely Immune-Compromised Patient with HIV Infection Treated with Acupuncture Giant warts are infrequent dermatological viral infections caused by Papillomavirus (HPV) in immune-compromised patients. Treatment may often be difficult and unsatisfactory, either by surgery or cytotoxic agents, because of poor immune control of viral activity in such hosts. Here we report on the case of a patient with advanced and persistent immune suppression caused by HIV

2011 Case reports in dermatology

76. Has Western medicine lost its soul?

Has Western medicine lost its soul? Has Western medicine lost its soul? | ScienceBlogs Advertisment Search Search Toggle navigation Main navigation Has Western medicine lost its soul? By on June 23, 2015. If there's one message that I've been trying to promote, regardless of whether it's on this blog or my not-so-super-secret other blog, it's the concept that there should be one standard of evidence—one scientific standard of evidence—for evaluating health claims and medical treatments (...) . It doesn't matter if it's the latest drug from big pharma, the latest operation from a hot shot surgeon with a lot of creativity and not necessarily the most rigorous dedication to science- and evidence-based medicine, the woo-filled claims of alternative medicine practitioners, or the seemingly "evidence-based" claims of physicians deluded enough to "integrate" quackery with medicine and call it "integrative medicine." That's the beauty of science. Unfortunately, those who would "integrate

2015 Respectful Insolence

77. GATA2 deficiency: a protean disorder of hematopoiesis, lymphatics, and immunity. Full Text available with Trip Pro

GATA2 deficiency: a protean disorder of hematopoiesis, lymphatics, and immunity. Haploinsufficiency of the hematopoietic transcription factor GATA2 underlies monocytopenia and mycobacterial infections; dendritic cell, monocyte, B, and natural killer (NK) lymphoid deficiency; familial myelodysplastic syndromes (MDS)/acute myeloid leukemia (AML); and Emberger syndrome (primary lymphedema with MDS). A comprehensive examination of the clinical features of GATA2 deficiency is currently lacking. We (...) reviewed the medical records of 57 patients with GATA2 deficiency evaluated at the National Institutes of Health from January 1, 1992, to March 1, 2013, and categorized mutations as missense, null, or regulatory to identify genotype-phenotype associations. We identified a broad spectrum of disease: hematologic (MDS 84%, AML 14%, chronic myelomonocytic leukemia 8%), infectious (severe viral 70%, disseminated mycobacterial 53%, and invasive fungal infections 16%), pulmonary (diffusion 79% and ventilatory

2014 Blood

78. The Role of Vitamin D in Female Reproductive Tract Immunity

supplementation. Assessment of immune cell activation and phenotype by IHC in CV tissues [ Time Frame: over 8 weeks of use ] Assess immune cell activation and phenotype by IHC in CV tissues before and after VitD and calcium supplementation. Eligibility Criteria Go to Information from the National Library of Medicine Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you (...) Contacts and Locations Go to Information from the National Library of Medicine To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor. Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02186535 Locations Layout table for location information United States, Virginia Eastern Virginia Medical School CONRAD Clinical Research Center Norfolk, Virginia, United States, 23507 Sponsors

2014 Clinical Trials

79. Evaluation of Long Term Immunity Following HPV Vaccination

Evaluation of Long Term Immunity Following HPV Vaccination Evaluation of Long Term Immunity Following HPV Vaccination - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Evaluation of Long Term Immunity (...) will be administered to all girls so that the magnitude of the memory responses can be measured. Condition or disease Intervention/treatment Cervical Cancer Anogenital Warts Biological: Cervarix® Study Design Go to Layout table for study information Study Type : Observational Actual Enrollment : 200 participants Observational Model: Cohort Time Perspective: Retrospective Official Title: Evaluation of Long-term Immunological Responses Following Reduced Dose Quadrivalent Human Papillomavirus (HPV) Vaccine Schedules

2014 Clinical Trials

80. Adolescent consent for vaccination: a position paper of the Society for Adolescent Health and Medicine. (Abstract)

Adolescent consent for vaccination: a position paper of the Society for Adolescent Health and Medicine. Vaccines currently recommended for adolescents by the Advisory Committee on Immunization Practices have the potential to improve the health of youth by preventing conditions such as: tetanus, pertussis, meningococcal disease, influenza, and genital warts, as well as later adult outcomes such as cervical and other human papillomavirus-related cancers. Adolescent vaccine coverage lags behind (...) to minors. All states have some laws that allow minors to consent to health care based either on their status or on the services they are seeking. Some of these laws would allow them to consent to vaccination. It is the Position of the Society for Adolescent Health and Medicine that, within ethical and legal guidelines, it will be important to develop strategies that maximize opportunities for minors to receive vaccinations when parents are not physically present, including opportunities for them

2013 The Journal of Adolescent Health

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