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Wart Treatment

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1. Topical Cantharidin/ Salicylic Acid/ Podophyllin for the Treatment of Warts: Clinical Effectiveness and Guidelines

Topical Cantharidin/ Salicylic Acid/ Podophyllin for the Treatment of Warts: Clinical Effectiveness and Guidelines Topical Cantharidin/ Salicylic Acid/ Podophyllin for the Treatment of Warts: Clinical Effectiveness and Guidelines | CADTH.ca Find the information you need Topical Cantharidin/ Salicylic Acid/ Podophyllin for the Treatment of Warts: Clinical Effectiveness and Guidelines Topical Cantharidin/ Salicylic Acid/ Podophyllin for the Treatment of Warts: Clinical Effectiveness (...) and Guidelines Last updated: January 21, 2019 Project Number: RA1006-000 Product Line: Research Type: Drug Report Type: Reference List Result type: Report Question What is the comparative clinical effectiveness of topical cantharidin/salicylic acid/podophyllin versus other topical treatments for warts? What are the evidence-based guidelines for the topical treatment of warts? Key Message One non-randomized study and two evidence-based guidelines were identified regarding topical cantharidin/ salicylic acid

2019 Canadian Agency for Drugs and Technologies in Health - Rapid Review

2. Oral cimetidine as the treatment of common warts

Oral cimetidine as the treatment of common warts Oral cimetidine as the treatment of common warts – Morsels of Evidence \t\t\t\r\n\t\t\t \t\t\t\r\n\t\t\t Like this: Like Loading... ","author":{"@type":"Person","name":"Michael Tam"},"image":["https:\/\/evidencebasedmedicine.com.au\/wp-content\/uploads\/2019\/01\/MO-DecJan2019cover.png"]} Toggle search form Toggle navigation Evidence-based medicine for general practitioners Jan 07 2019 Oral cimetidine as the treatment of common warts (...) By in , Journal reference: Yilmaz E, Alpsoy E, Basaran E. Cimetidine therapy for warts: a placebo-controlled, double-blind study. J Am Acad Dermatol 1996 Jun;34(6):1005-7 Link: Published: June 1996 Evidence cookie says… The limited research evidence does not support the use of oral cimetidine as the treatment of common warts anecdotal evidence of major benefits are not seen in blinded randomised trials although cimetidine is often seen as benign, side-effects were reported in a fifth of participants in one

2019 Morsels of Evidence

3. Oral cimetidine as the treatment of common warts

Oral cimetidine as the treatment of common warts Oral cimetidine as the treatment of common warts – Morsels of Evidence \t\t\t\r\n\t\t\t \t\t\t\r\n\t\t\t Share this: Like this: Like Loading... ","author":{"@type":"Person","name":"Michael Tam"},"image":["https:\/\/evidencebasedmedicine.com.au\/wp-content\/uploads\/2019\/01\/MO-DecJan2019cover.png"]} Toggle search form Toggle navigation Evidence-based medicine for general practitioners Jan 07 2019 Oral cimetidine as the treatment of common warts (...) By in , 7 January 2019 Journal reference: Yilmaz E, Alpsoy E, Basaran E. Cimetidine therapy for warts: a placebo-controlled, double-blind study. J Am Acad Dermatol 1996 Jun;34(6):1005-7 Link: Published: June 1996 Evidence cookie says… The limited research evidence does not support the use of oral cimetidine as the treatment of common warts anecdotal evidence of major benefits are not seen in blinded randomised trials although cimetidine is often seen as benign, side-effects were reported in a fifth

2019 Morsels of Evidence

4. A commonly used surface treatment is the most suitable first-line treatment for genital warts

A commonly used surface treatment is the most suitable first-line treatment for genital warts A commonly used surface treatment is the most suitable first-line treatment for genital warts Discover Portal Discover Portal A commonly used surface treatment is the most suitable first-line treatment for genital warts Published on 2 August 2016 doi: Podophyllotoxin 0.5% solution followed by carbon dioxide laser therapy only if unsuccessful may be the best treatment approach for anal and genital warts (...) . Either of these treatments can successfully clear warts in over three quarters of people. The podophyllotoxin 0.5% solution can be applied to the warts twice a day for three days at home. Further courses can be applied if necessary after a break of four days. Alternatively, carbon dioxide laser therapy is performed under local or general anaesthetic. Soreness and irritation is common after laser therapy but it is effective and also more useful for warts in less accessible places. The results

2019 NIHR Dissemination Centre

5. Imiquimod for the Treatment of Genital Warts: A Review of Clinical Effectiveness and Cost-Effectiveness

Imiquimod for the Treatment of Genital Warts: A Review of Clinical Effectiveness and Cost-Effectiveness Imiquimod for the Treatment of Genital Warts: A Review of Clinical Effectiveness and Cost-Effectiveness | CADTH.ca Find the information you need Imiquimod for the Treatment of Genital Warts: A Review of Clinical Effectiveness and Cost-Effectiveness Imiquimod for the Treatment of Genital Warts: A Review of Clinical Effectiveness and Cost-Effectiveness Published on: September 25, 2017 Project (...) Number: RC0930-000 Product Line: Research Type: Drug Report Type: Summary with Critical Appraisal Result type: Report Question What is the clinical effectiveness of imiquimod for the treatment of genital warts? What is the cost-effectiveness of imiquimod for the treatment of genital warts? Key Message Evidence from systematic reviews with low quality included studies suggests that overall for patients with anogenital warts (AGW) compared to placebo, treatment with imiquimod (IMQ) is associated

2017 Canadian Agency for Drugs and Technologies in Health - Rapid Review

6. Clinical effectiveness and cost-effectiveness of interventions for the treatment of anogenital warts: systematic review and economic evaluation

Clinical effectiveness and cost-effectiveness of interventions for the treatment of anogenital warts: systematic review and economic evaluation Clinical effectiveness and cost-effectiveness of interventions for the treatment of anogenital warts: systematic review and economic evaluation Journals Library An error occurred retrieving content to display, please try again. >> >> >> Page Not Found Page not found (404) Sorry - the page you requested could not be found. Please choose a page from

2016 NIHR HTA programme

7. A commonly used surface treatment is the most suitable first-line treatment for genital warts

A commonly used surface treatment is the most suitable first-line treatment for genital warts A commonly used surface treatment is the most suitable first-line treatment for genital warts Discover Portal Discover Portal A commonly used surface treatment is the most suitable first-line treatment for genital warts Published on 2 August 2016 doi: Podophyllotoxin 0.5% solution followed by carbon dioxide laser therapy only if unsuccessful may be the best treatment approach for anal and genital warts (...) . Either of these treatments can successfully clear warts in over three quarters of people. The podophyllotoxin 0.5% solution can be applied to the warts twice a day for three days at home. Further courses can be applied if necessary after a break of four days. Alternatively, carbon dioxide laser therapy is performed under local or general anaesthetic. Soreness and irritation is common after laser therapy but it is effective and also more useful for warts in less accessible places. The results

2018 NIHR Dissemination Centre

8. Genital warts

Genital warts Genital warts - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Genital warts Last reviewed: February 2019 Last updated: February 2019 Summary Very common STI. Caused by human papillomavirus (HPV) infection, most commonly HPV types 6 and 11. Peak incidence of genital HPV infection occurs in 16- to 25-year-olds. Diagnosis is made based on clinical presentation. Generally has a benign course (...) and is not often associated with oncogenic potential. Treatment can be challenging, as there is no cure and recurrences are common. Definition Genital warts are the most prevalent form of viral genital mucosal lesions and are caused by infection with several types of human papillomavirus (HPV). Mansur CP. Human papillomaviruses. In: Tyring SK, ed. Mucocutaneous manifestations of viral diseases. New York, NY: Marcel Dekker; 2002:247-94. The infection manifests as verrucous fleshy papules that may coalesce

2019 BMJ Best Practice

9. Evaluation of combined treatment with long-pulsed neodymium-doped yttrium aluminum garnet laser and potassium hydroxide for the treatment of recalcitrant wart: a prospective comparative study. (PubMed)

Evaluation of combined treatment with long-pulsed neodymium-doped yttrium aluminum garnet laser and potassium hydroxide for the treatment of recalcitrant wart: a prospective comparative study. Background: Lasers have been used for verruca treatment in recent years with successful results in some types. In addition, peeling processes have been used to enhance penetration in some studies. Objectives: This study aimed to evaluate combined treatment with LP Nd:YAG laser and KoH for the treatment (...) of recalcitrant wart. Methods: This study included 132 lesions from 38 patients. Long-pulsed (LP) Nd:YAG laser was applied to 66 lesions with daily 10% KOH application at night, and the remaining 66 lesions underwent LP Nd:YAG laser therapy only. Results: Both groups showed statistically significant regressions in the size of the lesions at the end of the fifth session compared with those present at the onset of therapy (p < .05). Also, complete clearance of the lesions was noticed after 2.2 sessions

2019 Journal of Dermatological Treatment

10. Genital warts

Genital warts Genital warts - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Genital warts Last reviewed: February 2019 Last updated: February 2019 Summary Very common STI. Caused by human papillomavirus (HPV) infection, most commonly HPV types 6 and 11. Peak incidence of genital HPV infection occurs in 16- to 25-year-olds. Diagnosis is made based on clinical presentation. Generally has a benign course (...) and is not often associated with oncogenic potential. Treatment can be challenging, as there is no cure and recurrences are common. Definition Genital warts are the most prevalent form of viral genital mucosal lesions and are caused by infection with several types of human papillomavirus (HPV). Mansur CP. Human papillomaviruses. In: Tyring SK, ed. Mucocutaneous manifestations of viral diseases. New York, NY: Marcel Dekker; 2002:247-94. The infection manifests as verrucous fleshy papules that may coalesce

2018 BMJ Best Practice

11. Common warts

Common warts Common warts - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Common warts Last reviewed: February 2019 Last updated: January 2018 Summary Common warts, also known as verrucae vulgaris, are caused by HPV infection and affect most people during their lifetimes. They are most common in children and young adults. Common warts should be distinguished from serious conditions that mimic them, such as squamous (...) cell carcinoma, especially in immunocompromised patients. The goals of treatment are to destroy the lesion, induce cytotoxicity against infected cells, and promote antiviral immunoresponsiveness to prevent recurrence. Best outcomes are achieved with a combination of destructive and immunosensitising approaches. Most common warts in healthy people resolve spontaneously. Clearance rates in children from time of diagnosis to clearance are 23% at 2 months, 30% at 3 months, 65% to 78% at 2 years, and 90

2018 BMJ Best Practice

12. Green tea leaf extract (Veregen) - an aggressive topical treatment for anogenital warts

Green tea leaf extract (Veregen) - an aggressive topical treatment for anogenital warts Prescrire IN ENGLISH - Spotlight ''In the April issue of Prescrire International: Green tea leaf extract (Veregen°) - an aggressive topical treatment for anogenital warts'', 1 April 2015 {1} {1} {1} | | > > > In the April issue of Prescrire International: Green tea leaf extract (Veregen°) - an aggressive topical treatment for anogenital warts Spotlight Every month, the subjects in Prescrire’s Spotlight. 100 (...) most recent :  |   |   |   |   |   |   |   |   |  Spotlight In the April issue of Prescrire International: Green tea leaf extract (Veregen°) - an aggressive topical treatment for anogenital warts FREE DOWNLOAD In this sample page from the New Products section: while drugs obtained from plants have the reputation of being innocuous, they sometimes provoke serious adverse effects. Full text available for free download. Summary

2015 Prescrire

13. Topical treatments for external genital warts in non-immunocompromised patients: a systematic review and network meta-analysis

Topical treatments for external genital warts in non-immunocompromised patients: a systematic review and network meta-analysis Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration record, any (...) , this assumption is unlikely to hold true for data from animal studies, which generally include various species, strains and treatment regimes, for which different true effects are likely to exist. The random-effects model takes into account both the within-study (sampling error) and between-study (differences in the true effect size) variance. Should the excessive between-study variance be very low or zero, the random-effects model will yield the same results as the fixed-effect model. For further details

2019 PROSPERO

14. Efficacy of bleomycin application on periungual warts after treatment with ablative carbon dioxide fractional laser: a pilot study. (PubMed)

Efficacy of bleomycin application on periungual warts after treatment with ablative carbon dioxide fractional laser: a pilot study. Treating periungual warts is a therapeutic challenge. Treatments are often ineffective and may cause complications including permanent nail changes, pain, and scaring. Translesional bleomycin delivery via the multipuncture technique is now reported.To investigate the efficacy and safety of bleomycin solution (1 U/mL) after ablative fractional carbon dioxide (CO2 (...) ) laser for treating periungual warts.Warts were treated with ablative CO2 fractional laser, after which bleomycin was applied. Patients were treated every 2 weeks until the lesions disappeared. Treatment was discontinued if adverse events occurred or the patient wanted to stop.Seventeen patients (11 women, mean age 16.23 years) with a total of 38 warts were enrolled from May 2017 to Aug 2018. Twenty-six lesions (68.4%) achieved complete clearance; three (7.8%) had excellent partial response (>75

2019 Journal of Dermatological Treatment

15. Ungual warts: comparison of treatment with intralesional bleomycin and electroporation in terms of efficacy and safety. (PubMed)

Ungual warts: comparison of treatment with intralesional bleomycin and electroporation in terms of efficacy and safety. Ungual warts are considered the most common benign nail tumour, and they are caused by the human papillomavirus. Despite the numerous treatments reported in the medical literature, ungual warts are considered frustrating, with high relapse rates and a potential risk of nail dystrophy. Bleomycin is a therapeutic option showing a good safety profile and high cure rates.To (...) evaluate the efficacy of electrochemotherapy using intralesional bleomycin for the treatment of ungual warts in comparison with intralesional bleomycin alone and describe the side-effects related to the use of both techniques.This was a prospective, randomized, double-blind, controlled clinical trial. Forty-four 18- to 60-year-old female and male patients with ungual warts of only one finger were included. The patients were divided into two treatment groups: GA - intralesional bleomycin; and GB

2019 Journal of the European Academy of Dermatology and Venereology

16. Successful Treatment of Multiple Common Warts With Intralesional Ozone. (PubMed)

Successful Treatment of Multiple Common Warts With Intralesional Ozone. Although there are multiple treatments for warts, wart management remains a challenge. Ozone therapy is an emerging treatment for infectious and noninfectious dermatological diseases.To assess intralesional ozone gas safety and efficacy in multiple warts management.Seventy-four adult patients with multiple common warts were included in this study. They were randomly assigned into 2 groups: first group comprised 44 patients (...) treated with intralesional ozone gas, and the second group comprised 30 patients who received intralesional saline injection. In both groups, warts in all patients were directly injected weekly until complete clearance occurred or for a maximum of 10 treatment sessions. The subjects were followed for 6 months to record any recurrences.In the ozone group, 25 patients (56.8%) had a complete response with an excellent cosmetic outcome, 15 patients (34.1%) showed a partial response, and 4 patients (9.1

2019 Dermatologic Surgery

17. Intralesional injection of vitamin D3 versus zinc sulfate 2% in treatment of plantar warts: a comparative study. (PubMed)

Intralesional injection of vitamin D3 versus zinc sulfate 2% in treatment of plantar warts: a comparative study. Background: Plantar warts are common skin lesions caused by the human papilloma virus. It is characterized by the presence of a horny ring of hyperkeratosis surrounding the wart, making its elimination a therapeutic challenge. Several destructive agents are available for treatment with variable success. Intralesional vitamin D3 has been reported as a successful treatment of warts (...) . Intralesional zinc sulfate has been found to be another successful therapeutic modality for wart elimination. Objective: To compare the efficacy and safety of intralesional vit. D3 versus zinc sulfate in treatment of plantar warts. Patients and methods: Forty patients were included in the study. Patients were randomly assigned to either vit. D3 group or zinc group. In vit. D3 group, patients received intralesional injection of 0.3 ml vitamin D3 (100,000 IU (2.5 mg/ml)), while zinc group patients received

2019 Journal of Dermatological Treatment

18. Intralesional versus intramuscular bivalent human papillomavirus vaccine in the treatment of recalcitrant common warts. (PubMed)

Intralesional versus intramuscular bivalent human papillomavirus vaccine in the treatment of recalcitrant common warts. Despite the availability of different therapeutic modalities, treatment of recalcitrant common warts is still challenging. Cervarix, a recombinant bivalent human papillomavirus (HPV) vaccine, has shown promising efficacy in the treatment of warts.To evaluate the beneficial effects and tolerability of intramuscular versus intralesional bivalent HPV vaccine in the treatment (...) of recalcitrant common warts.The study included 44 adult patients with multiple recalcitrant common warts; 22 patients were injected with intramuscular bivalent HPV vaccine at 0, 1, and 6 months or until complete clearance of warts and the other 22 patients were intralesionally injected with 0.1 to 0.3 ml of bivalent HPV vaccine into the largest wart at 2-week intervals until complete clearance or for a maximum of six sessions.Complete clearance of warts was observed in 18 patients (81.8

2019 Journal of American Academy of Dermatology

19. Successful treatment of recalcitrant plantar warts by carbon dioxide laser with a computerized scanner. (PubMed)

Successful treatment of recalcitrant plantar warts by carbon dioxide laser with a computerized scanner. Warts are benign neoplasms of the skin and mucosa caused by human papillomavirus (HPV) infection.1 The most common treatments for wart are topical application of salicylic acid and cryotherapy. Other modalities include chemical agents, contact sensitizing agents and surgical excision.2 Laser modalities, including carbon dioxide (CO2 ), pulsed dye and neodymium-doped: yttrium-aluminum-garnet (...) lasers, have also been used to treat recalcitrant plantar warts.© 2019 British Association of Dermatologists.

2019 British Journal of Dermatology

20. Duct tape to treat cutaneous warts

, Holland R, Abbott R. Topical treatments for cutaneous warts. Cochrane database of systematic reviews 2012 Sep 12(9):CD001781 Link: Published: September 2012 Evidence cookie says… Duct tape should not be routinely recommended as wart therapy. There is no compelling evidence that duct tape is more effective than placebo. Clinical scenario Krystal, a 21-year-old office worker saw me recently with common warts on her hand. She mentioned that her mother had suggested that she use duct tape. I recalled (...) that in a recent discussion on the online group GPs Down Under , duct tape had its advocates. What is the evidence? Clinical question What is the effect of applying duct tape as treatment on the recovery of common warts? What does the research evidence say? Step 1: The Cochrane Library The Cochrane Library has a systematic review that is update-to-date to May 2011 on topical treatments for warts, including duct tape [1]. Step 2: TripDatabase & PubMed I conducted a search using the TripDatabase PICO search tool

2017 Morsels of Evidence

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