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Vitiligo

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101. Microneedling and Latanoprost in Acrofacial Vitiligo

Microneedling and Latanoprost in Acrofacial Vitiligo Microneedling and Latanoprost in Acrofacial Vitiligo - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Microneedling and Latanoprost in Acrofacial Vitiligo (...) by (Responsible Party): Noreen Ismail AbdelGhani Ahmed, Sohag University Study Details Study Description Go to Brief Summary: To compare efficacy of topical latanoprost preceded by microneedling versus topical latanoprost alone in treatment of acrofacial vitiligo. Condition or disease Intervention/treatment Phase Vitiligo Drug: Latanoprost Device: Microneedling Phase 2 Phase 3 Detailed Description: patients meeting inclusion and exclusion criteria presented to Dermatology Outpatient Clinic, Sohag University

2018 Clinical Trials

102. Efficacy and Safety of Total Glucosides of Paeony Combined With NB-UVB on Treating Vitiligo

Efficacy and Safety of Total Glucosides of Paeony Combined With NB-UVB on Treating Vitiligo Efficacy and Safety of Total Glucosides of Paeony Combined With NB-UVB on Treating Vitiligo - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more (...) studies before adding more. Efficacy and Safety of Total Glucosides of Paeony Combined With NB-UVB on Treating Vitiligo The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT03608917 Recruitment Status : Enrolling by invitation First Posted : August 1, 2018 Last Update Posted : August 1, 2018 Sponsor: xjpfW

2018 Clinical Trials

103. A Study of ATI-50002 Topical Solution for the Treatment of Vitiligo

A Study of ATI-50002 Topical Solution for the Treatment of Vitiligo A Study of ATI-50002 Topical Solution for the Treatment of Vitiligo - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. A Study of ATI-50002 (...) Topical Solution for the Treatment of Vitiligo The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT03468855 Recruitment Status : Active, not recruiting First Posted : March 19, 2018 Last Update Posted : January 8, 2019 Sponsor: Aclaris Therapeutics, Inc. Information provided by (Responsible Party): Aclaris

2018 Clinical Trials

104. Comparative Study of Surgical Treatment of Vitiligo

Comparative Study of Surgical Treatment of Vitiligo Comparative Study of Surgical Treatment of Vitiligo - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Comparative Study of Surgical Treatment of Vitiligo (...) by (Responsible Party): Hospital de Clinicas de Porto Alegre Study Details Study Description Go to Brief Summary: A comparative study for the surgical treatment of vitiligo in which the same patient will receive in acromic and symmetric lesions of vitiligo dermabrasion with micro needling and on the other side dermabrasion with micro needling followed by the application of cell suspension (melanocytes and uncultured keratinocytes). These cells will be removed from the own patient through the skin of the scalp

2018 Clinical Trials

105. Bimatoprost 0.03% Solution With NB-UVB Versus Their Use With Fractional Carbon Dioxide Laser in Treatment of Generalized Vitiligo

Bimatoprost 0.03% Solution With NB-UVB Versus Their Use With Fractional Carbon Dioxide Laser in Treatment of Generalized Vitiligo Bimatoprost 0.03% Solution With NB-UVB Versus Their Use With Fractional Carbon Dioxide Laser in Treatment of Generalized Vitiligo - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have (...) reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Bimatoprost 0.03% Solution With NB-UVB Versus Their Use With Fractional Carbon Dioxide Laser in Treatment of Generalized Vitiligo The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before

2018 Clinical Trials

106. Leucotrichia in Vitiligo

Leucotrichia in Vitiligo Leucotrichia in Vitiligo - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Leucotrichia in Vitiligo The safety and scientific validity of this study is the responsibility of the study (...) to 48.4% of all vitiligo patients.Leucotrichia is more often observed in segmental vitiligo with a very high percentage. However, further studies considering the prevalence of leucotrichia in different types of vitiligo need to be conducted. Condition or disease Intervention/treatment Leucotrichia Other: Examination of leukotrichia in vitiligo patients Study Design Go to Layout table for study information Study Type : Observational Actual Enrollment : 107 participants Observational Model: Case-Only

2018 Clinical Trials

107. The Gut and Skin Microbiome in Vitiligo Disease Progression

The Gut and Skin Microbiome in Vitiligo Disease Progression The Gut and Skin Microbiome in Vitiligo Disease Progression - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. The Gut and Skin Microbiome (...) in Vitiligo Disease Progression The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03577327 Recruitment Status : Not yet recruiting First Posted : July 4, 2018 Last Update Posted : July 4, 2018 See Sponsor: Northwestern University

2018 Clinical Trials

108. Comparing Recipient Site Preparation Using Dermabrasion, Dermaroller and Liquid Nitrogen Induced Blister in Non Cultured Epidermal Cell Suspension in Stable Vitiligo

Comparing Recipient Site Preparation Using Dermabrasion, Dermaroller and Liquid Nitrogen Induced Blister in Non Cultured Epidermal Cell Suspension in Stable Vitiligo Comparing Recipient Site Preparation Using Dermabrasion, Dermaroller and Liquid Nitrogen Induced Blister in Non Cultured Epidermal Cell Suspension in Stable Vitiligo - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x (...) × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Comparing Recipient Site Preparation Using Dermabrasion, Dermaroller and Liquid Nitrogen Induced Blister in Non Cultured Epidermal Cell Suspension in Stable Vitiligo The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated

2018 Clinical Trials

109. Effects of Camouflage on the Life Quality of Patients With Vitiligo

Effects of Camouflage on the Life Quality of Patients With Vitiligo Effects of Camouflage on the Life Quality of Patients With Vitiligo - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Effects of Camouflage (...) on the Life Quality of Patients With Vitiligo The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03540966 Recruitment Status : Recruiting First Posted : May 30, 2018 Last Update Posted : May 30, 2018 See Sponsor: Xijing Hospital

2018 Clinical Trials

110. Efficiency of Fractional-Laser Resurfacing Followed by Topical Tacrolimus 0.03% Cream vs Tacrolimus Alone in Vitiligo

Efficiency of Fractional-Laser Resurfacing Followed by Topical Tacrolimus 0.03% Cream vs Tacrolimus Alone in Vitiligo Efficiency of Fractional-Laser Resurfacing Followed by Topical Tacrolimus 0.03% Cream vs Tacrolimus Alone in Vitiligo - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number (...) of saved studies (100). Please remove one or more studies before adding more. Efficiency of Fractional-Laser Resurfacing Followed by Topical Tacrolimus 0.03% Cream vs Tacrolimus Alone in Vitiligo The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT03535051 Recruitment Status : Completed First Posted : May

2018 Clinical Trials

111. A Phase 2b Study To Evaluate The Efficacy And Safety Profile Of PF-06651600 And PF-06700841 In Active Non-segmental Vitiligo Subjects

A Phase 2b Study To Evaluate The Efficacy And Safety Profile Of PF-06651600 And PF-06700841 In Active Non-segmental Vitiligo Subjects A Phase 2b Study To Evaluate The Efficacy And Safety Profile Of PF-06651600 And PF-06700841 In Active Non-segmental Vitiligo Subjects - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You (...) have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. A Phase 2b Study To Evaluate The Efficacy And Safety Profile Of PF-06651600 And PF-06700841 In Active Non-segmental Vitiligo Subjects The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before

2018 Clinical Trials

112. Platelet-rich plasma versus combined fractional carbon dioxide laser with platelet-rich plasma in the treatment of vitiligo: a comparative study. (PubMed)

Platelet-rich plasma versus combined fractional carbon dioxide laser with platelet-rich plasma in the treatment of vitiligo: a comparative study. The aim of this study was to assess the efficacy of platelet-rich plasma (PRP) vs combined fractional CO2 (Fr: CO2) laser with PRP in the treatment of stable nonsegmental vitiligo (NSV) lesions.This prospective, randomized, intrapatient, comparative controlled study was conducted between June 2014 and June 2016 at National Institute of Laser Enhanced (...) Sciences (NILES), Cairo University, Cairo, Egypt. Thirty NSV patients were treated with PRP, Fr: CO2 laser, and combined Fr: CO2 laser with PRP. Intrapatient lesions were divide randomly into four groups. Each group was treated by one modality. The fourth group served as a control.Patients received six treatment sessions with 2-week interval for 3 months and were followed up after 3 months.A highly significant reduction was demonstrated through vitiligo analysis by computer-assisted grid (VACAG

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2018 Clinical, cosmetic and investigational dermatology

113. Intradermal injection of Fluorouracil versus triamcinolone in localized vitiligo treatment. (PubMed)

Intradermal injection of Fluorouracil versus triamcinolone in localized vitiligo treatment. Vitiligo is an autoimmune disease with a prevalence of 1.22% in Egypt. Intralesional steroids use in localized vitiligo treatment still a matter of debate. Fluorouracil was tried in vitiligo treatment after lesion dermabrasion, ablative laser, or micro-needling. The study aimed to compare the efficacy of intradermal fluorouracil and triamcinolone acetonide without any adjuvant therapy in localized (...) vitiligo treatment.Sixty patients with localized non-segmental stable vitiligo were assigned randomly and equally into groups. Patients subjected to intradermal injection of either fluorouracil (50 mg/mL), triamcinolone acetonide (3 mg/mL) or an equal mixture of both drugs. All patients had four treatment sessions every 2 weeks were followed up for 6 months.Intradermal fluorouracil showed the best overall improvement (median 52.27, IQR 36.25-68.18) when compared with triamcinolone (median 13.86, IQR

2018 Journal of cosmetic dermatology

114. The role of long-wavelength ultraviolet A1 (UVA1) in acral vitiligo. (PubMed)

The role of long-wavelength ultraviolet A1 (UVA1) in acral vitiligo. Acral vitiligo is a resistant subtype of vitiligo that does not respond easily to any treatment modality. Ultraviolet A1 (UVA1) (340-400 nm) therapy can penetrate the deep dermis of the skin and is relatively free of adverse effects associated with different phototherapeutic modalities. This study's objective was to evaluate the effect of medium-dose long-wavelength UVA1 (40-70 J) in acral vitiligo treatment and compare (...) it with topical psoralen plus ultraviolet A (topical PUVA).Patients in this randomized-controlled comparative clinical trial were divided into two groups, medium-dose UVA1 group and topical PUVA group (10 acral vitiligo patients each). Patients received 36 sessions of phototherapy over a period of 12 weeks. Every patient was clinically evaluated monthly as regards the appearance of new lesions or increase in diameter of the current lesion according to point counting and vitiligo area severity index.No

2018 Journal of cosmetic dermatology

115. Vitiligo in a patient undergoing nivolumab treatment for non–small cell lung cancer (PubMed)

Vitiligo in a patient undergoing nivolumab treatment for non–small cell lung cancer 30456282 2019 02 26 2352-5126 4 10 2018 Nov JAAD case reports JAAD Case Rep Vitiligo in a patient undergoing nivolumab treatment for non-small cell lung cancer. 1042-1044 10.1016/j.jdcr.2018.08.009 Kosche Cory C Department of Dermatology, Northwestern University, Feinberg School of Medicine, Chicago, Illinois. Mohindra Nisha N Department of Internal Medicine, Division of Hematology and Oncology, Northwestern (...) University, Feinberg School of Medicine, Chicago, Illinois. Choi Jennifer N JN Department of Dermatology, Northwestern University, Feinberg School of Medicine, Chicago, Illinois. eng Case Reports 2018 11 10 United States JAAD Case Rep 101665210 2352-5126 NSCLC, non–small cell lung cancer PD-1 inhibitor PD-1, programmed cell death protein 1 PD-L1, programmed death ligand 1 adverse event checkpoint inhibitor immunotherapy nivolumab non–small cell lung cancer vitiligo 2018 11 21 6 0 2018 11 21 6 0 2018 11

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2018 JAAD Case Reports

116. Vitiligo Appearing after Oral Isotretinoin Therapy for Acne (PubMed)

Vitiligo Appearing after Oral Isotretinoin Therapy for Acne Isotretinoin is an effective treatment for severe and scarring acne. In this report, we describe a case developing vitiligo after isotretinoin therapy for scarring acne. It is not known whether this was a coincidence or might be precipitated by the treatment.

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2018 Case reports in dermatological medicine

117. Autologous non-cultured melanocyte–keratinocyte transplantation in the treatment of vitiligo: patient selection and perspectives (PubMed)

Autologous non-cultured melanocyte–keratinocyte transplantation in the treatment of vitiligo: patient selection and perspectives Autologous non-cultured melanocyte-keratinocyte transplantation procedure (MKTP) is one of the simplest cellular grafting techniques. Various modifications were done over the years to make the technique easier and more economical which led to its great popularity among dermatologists. Proper patient selection and good technical skills are essential for achieving

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2018 Clinical, cosmetic and investigational dermatology

118. Immunohistochemistry of Janus Kinase 1 (JAK1) Expression in Vitiligo (PubMed)

Immunohistochemistry of Janus Kinase 1 (JAK1) Expression in Vitiligo Vitiligo is a chronic autoimmune disease in which the destruction of melanocytes causes white spots on the affected skin. Janus kinase (JAK) is a family of intracellular, non-receptor tyrosine kinases that transduce cytokine-mediated signals via the JAK-signal transducer and activator of transcription pathway. The aim of the present study is to explore the possible role of JAK1 in the pathogenesis of vitiligo using (...) immunohistochemical methods.The current study was conducted in a sample of 39 patients who presented with vitiligo and 22 healthy individuals who were age and sex matched as a control group. We used immunohistochemistry to evaluate JAK1 status (intensity and distribution) and assess the percentage of residual melanocytes using human melanoma black 45 (HMB45).Intense and diffuse JAK1 expression was significantly more likely to indicate vitiliginous skin compared to normal skin (p < .001). Strong and diffuse JAK1

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2018 Journal of Pathology and Translational Medicine

119. Treatment outcome and persistence of repigmentation from narrow-band ultraviolet B phototherapy in vitiligo. (PubMed)

Treatment outcome and persistence of repigmentation from narrow-band ultraviolet B phototherapy in vitiligo. Narrow-band ultraviolet B (NB-UVB) phototherapy is a mainstay treatment in vitiligo. However, data relative to repigmentation outcome, prognostic factors, and duration of repigmentation are limited.To investigate the quantitative repigmentation outcome of NB-UVB phototherapy in vitiligo, the factors associated with favorable prognosis after NB-UVB, and the duration of repigmentation (...) after NB-UVB discontinuation.Medical records of vitiligo patients who underwent NB-UVB phototherapy at Department of Dermatology, Siriraj Hospital during 2012 to 2016 were retrospectively reviewed. Repigmentation was assessed using Vitiligo Area Scoring Index (VASI) score.Fifty-eight patients were included. All patients received NB-UVB phototherapy twice to three times weekly for a median duration of 12 months. Forty-two patients had non-segmental vitiligo (NSV), and 16 had segmental vitiligo (SV

2018 Journal of Dermatological Treatment

120. Identification of the Risk HLA-A Alleles and Autoantigen in Han Chinese Vitiligo Patients and the Association of CD8+T Cell Reactivity with Disease Characteristics (PubMed)

Identification of the Risk HLA-A Alleles and Autoantigen in Han Chinese Vitiligo Patients and the Association of CD8+T Cell Reactivity with Disease Characteristics BACKGROUND Multiple studies have implicated a role for CD8+T cell-mediated immune response to autoantigens in vitiligo. However, the antigen-specific T lymphocyte reactivity against the peptide epitopes is diverse among different world populations. This study aimed to identify the risk HLA-A allele in vitiligo and study CD8+ T cell (...) reactivity to 5 autoantigenic peptides in Han Chinese populations, and to analyze the association of CD8+ T cell reactivity with disease characteristics. MATERIAL AND METHODS The risk HLA-A allele was analyzed by case-control study. Enzyme linked immunospot (ELISPOT) assay was used to compare T cell reactivity to the 5 autoantigenic peptides between vitiligo patients and healthy controls, then we analyzed the association of CD8+ T cell reactivity to 2 positive peptides with disease activity and area

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2018 Medical science monitor : international medical journal of experimental and clinical research

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