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Vitamin B12 Supplementation

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23401. Folic acid and vitamin B-12 and B-6 supplements reduce blood homocysteine concentrations (Full text)

Folic acid and vitamin B-12 and B-6 supplements reduce blood homocysteine concentrations 9552872 1998 04 23 1756-1833 316 7135 1998 Mar 21 BMJ (Clinical research ed.) BMJ Folic acid and vitamin B-12 and B-6 supplements reduce blood homocysteine concentrations b eng Journal Article England BMJ 8900488 0959-8138 1998 4 29 1998 4 29 1998 4 29 0 0 ppublish 9552872 PMC1112800

1998 BMJ : British Medical Journal

23402. Florid rickets associated with prolonged breast feeding without vitamin D supplementation (Full text)

Florid rickets associated with prolonged breast feeding without vitamin D supplementation 9872885 1999 02 26 2018 11 13 0959-8138 318 7175 1999 Jan 02 BMJ (Clinical research ed.) BMJ Lesson of the week: florid rickets associated with prolonged breast feeding without vitamin D supplementation. 39-40 Mughal M Z MZ St Mary's Hospital, Central Manchester Healthcare Trust, Manchester M13 0JH. nwest.nhs.uk Salama H H Greenaway T T Laing I I Mawer E B EB eng Journal Article England BMJ 8900488 0959 (...) -8138 1406-16-2 Vitamin D AIM IM BMJ. 1999 Jan 2;318(7175):2-3 9872859 BMJ. 1999 May 22;318(7195):1417 10334764 BMJ. 2007 Jun 23;334(7607):1288 17585129 Breast Feeding adverse effects Dietary Supplements Humans Infant Rickets ethnology etiology Vitamin D administration & dosage Vitamin D Deficiency ethnology etiology 1999 1 5 1999 1 5 0 1 1999 1 5 0 0 ppublish 9872885 PMC1114534 Am J Dis Child. 1985 Nov;139(11):1134-7 2998180 Br Med J (Clin Res Ed). 1985 Jul 27;291(6490):239-42 3926136 Calcif Tissue

1999 BMJ : British Medical Journal

23403. Treating alcohol dependence. Supplementation with parenteral B vitamins should be routinely considered. (Full text)

Treating alcohol dependence. Supplementation with parenteral B vitamins should be routinely considered. 9418114 1998 01 14 2008 11 20 0959-8138 315 7120 1997 Nov 29 BMJ (Clinical research ed.) BMJ Treating alcohol dependence. Supplementation with parenteral B vitamins should be routinely considered. 1465; author reply 1466 Cook C C CC Thomson A D AD eng Comment Letter England BMJ 8900488 0959-8138 12001-76-2 Vitamin B Complex AIM IM BMJ. 1997 Aug 9;315(7104):358-60 9270461 Alcoholism (...) rehabilitation Humans Infusions, Parenteral Vitamin B Complex administration & dosage Vitamin B Deficiency prevention & control 1998 1 7 1998 1 7 0 1 1998 1 7 0 0 ppublish 9418114 PMC2127908

1997 BMJ : British Medical Journal

23404. The effect of vitamin A supplementation on the growth of preschool children in the Sudan. (Full text)

The effect of vitamin A supplementation on the growth of preschool children in the Sudan. This study assessed the effect of vitamin A supplementation at 6-month intervals on child growth.Sudanese children (n = 28,740) 6 to 72 months of age were weighed and measured at baseline and at each of three follow-up visits.Periodic vitamin A supplementation had no effect on the rate of weight or height gain in the total population or on the incidence of wasting, stunting, or wasting and stunting among

1997 American Journal of Public Health

23405. Regular vitamin D supplementation for housebound, frail elderly people. (Full text)

Regular vitamin D supplementation for housebound, frail elderly people. 9426931 1998 01 30 2018 11 13 0008-350X 43 1997 Dec Canadian family physician Medecin de famille canadien Can Fam Physician Regular vitamin D supplementation for housebound, frail elderly people. 2127-8 Pimlott N J NJ Women's College Hospital. Evans M F MF eng Comparative Study Journal Article Canada Can Fam Physician 0120300 0008-350X 0 Calcium, Dietary 1406-16-2 Vitamin D IM Aged Calcium, Dietary administration & dosage (...) Cohort Studies Female Follow-Up Studies Frail Elderly Homebound Persons House Calls Humans Male Nursing Homes Randomized Controlled Trials as Topic Time Factors Vitamin D administration & dosage blood Vitamin D Deficiency diagnosis prevention & control 1998 1 14 1998 1 14 0 1 1998 1 14 0 0 ppublish 9426931 PMC2255093 Arch Intern Med. 1991 Aug;151(8):1662-4 1872673 JAMA. 1995 Dec 6;274(21):1683-6 7474272 N Engl J Med. 1992 Jul 16;327(3):163-7 1608407

1997 Canadian Family Physician

23406. Effect of short term vitamin E supplementation on lipid peroxidation in acute myocardial infarction (Full text)

Effect of short term vitamin E supplementation on lipid peroxidation in acute myocardial infarction In view of sufficient body of evidence to substantiate the role of free radical mediated oxidative injury in myocardial infarction (M.I.), the utility of exogenous supplementation with antioxidant substance, vitamin E was studied. Forty patients of acute myocardial infarction were divided into two equal groups, one who received vitamin E and the other who did not. Plasma MDA levels showed (...) a reduction in patients of M.I. who received vitamin E as well as in those who did not, however, the decrease was significantly more in the vitamin E treated subgroup.

1998 Indian Journal of Clinical Biochemistry

23407. Effect of supplementation with vitamin A or β carotene on mortality related to pregnancy : Pooling of groups may not be appropriate (Full text)

Effect of supplementation with vitamin A or β carotene on mortality related to pregnancy : Pooling of groups may not be appropriate 10541530 1999 12 16 2018 11 13 0959-8138 319 7218 1999 Oct 30 BMJ (Clinical research ed.) BMJ Effect of supplementation with vitamin A or beta carotene on mortality related to pregnancy. Pooling of groups may not be appropriate. 1201-2; author reply 1203 Vijayaraghavan K K Krishnaswamy K K eng Comment Letter England BMJ 8900488 0959-8138 01YAE03M7J beta Carotene (...) 11103-57-4 Vitamin A AIM IM BMJ. 1999 Feb 27;318(7183):570-5 10037634 Dietary Supplements Female Humans Maternal Mortality Pregnancy Pregnancy Complications mortality Vitamin A administration & dosage beta Carotene administration & dosage 1999 12 14 1999 12 14 0 1 1999 12 14 0 0 ppublish 10541530 PMC1116978 BMJ. 1999 Feb 27;318(7183):570-5 10037634 BMJ. 1999 Feb 27;318(7183):551-2 10037611 J Nutr. 1998 Sep;128(9):1458-63 9732305 Br Med J. 1931 Oct 3;2(3691):595-8 20776417

1999 BMJ : British Medical Journal

23408. Childhood mortality impact and costs of integrating vitamin A supplementation into immunization campaigns. (Full text)

Childhood mortality impact and costs of integrating vitamin A supplementation into immunization campaigns. Country-specific activity and coverage data were used to estimate the childhood mortality impact (deaths averted) and costs of integrating vitamin A supplements into immunization campaigns conducted in 1998 and 1999. More than 94 million doses of vitamin A were administered in 41 countries in 1998, helping to avert nearly 169,000 deaths. During 1999, delivery of more than 97 million doses (...) in 50 countries helped avert an estimated 242,000 deaths. The estimated incremental cost per death averted was US$72 (range: 36-142) in 1998 and US$64 (range: 32-126) in 1999. The estimated average total cost of providing supplementation per death averted was US$310 (range: 157-609) in 1998 and US$276 (range: 139-540) in 1999. Costs per death averted varied by campaign, depending on the number and proportion of the child population reached, number of doses received per child, and child mortality

2000 American Journal of Public Health

23409. Vitamin E supplementation on biochemical changes observed in agricultural field workers exposed to different classes of pesticides (Full text)

Vitamin E supplementation on biochemical changes observed in agricultural field workers exposed to different classes of pesticides A total of 41 healthy male pesticide sprayers exposed to different clases of pesticides for 3-5 years were compared with 21 controls matched for age and economic status with respect to free radical generation, lipid peroxidation, antioxidant status, cholesterol, lipoprotein status and haematological profile. Plasma lipid peroxidation was estimated in the form (...) changes in hematological parameters were observed. These results suggested that exposure to pesticidal residual drift augments the free radical generation, and lipid peroxidation. Decline in non-enzymatic antioxidant and elevation of enzymatic antioxidant were observed. Supplementation of α-tocopherol for 45 days resulted in the partial restoration of these biochemical changes produced by pesticides.

2001 Indian Journal of Clinical Biochemistry

23410. Vitamin E supplementation increases T helper 1 cytokine production in old mice infected with influenza virus (Full text)

Vitamin E supplementation increases T helper 1 cytokine production in old mice infected with influenza virus Compared with young mice, old mice infected with influenza virus have significantly higher pulmonary viral titres, although these can be reduced significantly with dietary vitamin E supplementation. T helper 1 (Th1) cytokines, especially interferon-gamma (IFN-gamma), play an important role in defending against influenza infection. However, there is an age-associated loss of Th1 cytokine (...) production. Prostaglandin E2 (PGE2) production, which increases with age, can modulate the T helper cell function by suppressing Th1 cytokine production. To investigate the mechanism of vitamin E supplementation on reduction of influenza severity in old mice, we studied the cytokine production by splenocytes, and PGE2 production by macrophages (Mphi), in young and old C57BL mice fed semipurified diets containing 30 (control) or 500 parts per million (ppm) (supplemented) vitamin E for 8 weeks

2000 Immunology

23411. Plasma 25-hydroxyvitamin D concentrations in preterm infants receiving oral vitamin D supplements. (Full text)

Plasma 25-hydroxyvitamin D concentrations in preterm infants receiving oral vitamin D supplements. Plasma 25-hydroxy-cholecalciferol (25-OHD) was measured serially in two groups of preterm infants receiving either 400 IU or 1000 IU oral vitamin D3 daily. All the babies were able to absorb and hydroxylate vitamin D3 adequately by 36 weeks' gestational age. The higher daily supplement had no advantage over the lower dose.

1981 Archives of Disease in Childhood

23412. Patterns of vitamin C intake from food and supplements: survey of an adult population in Alameda County, California. (Full text)

Patterns of vitamin C intake from food and supplements: survey of an adult population in Alameda County, California. Use of vitamin C in food and pills and its association with health habits and health status were investigated in a random sample of 3,119 adults in Alameda County, California. Vitamin C intakes of nearly 80 per cent of respondents met or exceeded Recommended Daily Dietary Allowances. Fourteen per cent or fewer appeared to have inadequate vitamin C intake. Vitamin C supplements (...) were taken daily by 29 per cent, occasionally by 21 per cent. Most respondents obtained 100 mg or less of vitamin C daily; 2 per cent had more than 2000 mg. Proportionately, more women than men took vitamin C pills daily. Men aged 16 to 44 were the most likely to have neither vitamin C foods nor pills. Persons 45 years and older tended to take vitamin C pills daily, younger persons to take them occasionally. Respondents who did not eat breakfast or who smoked cigarettes had lower vitamin C intakes

1983 American Journal of Public Health

23413. Modification of chemically induced diabetes in rats by vitamin E. Supplementation minimizes and depletion enhances development of diabetes. (Full text)

Modification of chemically induced diabetes in rats by vitamin E. Supplementation minimizes and depletion enhances development of diabetes. Administration of the antioxidant vitamin E to rats, prior to administration of either streptozotocin or alloxan, provided protection against the diabetogenic effect of both these agents. This was demonstrated by their response to a glucose load, their pancreatic insulin content and light microscopy findings. In addition, rats whose antioxidant state (...) was depleted, by being maintained on a vitamin E and selenium-deficient diet, demonstrated increased diabetogenic susceptibility to normally nondiabetogenic doses of streptozotocin. These findings provide indirect support for the suggestion that the chemical agents streptozotocin and alloxan may exert their diabetogenic effect by acting as oxidants or free radical producers.

1983 Journal of Clinical Investigation

23414. Supplemental vitamin A prevents the acute radiation-induced defect in wound healing. (Full text)

Supplemental vitamin A prevents the acute radiation-induced defect in wound healing. Acute radiation injury leads to thymic involution, adrenal enlargement, leukopenia, thrombocytopenia, gastrointestinal ulceration, and impaired wound healing. The authors hypothesized that supplemental vitamin A would mitigate these adverse effects in rats exposed to acute whole-body radiation. This hypothesis was based on previous experiments in their laboratory that showed that supplemental vitamin (...) incisions and subcutaneous implantation of polyvinyl alcohol sponges were performed in anesthetized Sprague-Dawley rats at varying times following sham radiation or varying doses of whole-body radiation (175-850 rad). In each experiment, the control diet [which contains about 18,000 IU vit. A/kg chow (3 X the NRC RDA for normal rats)] was supplemented with 150,000 IU vit. A/kg diet beginning at, before, or after sham radiation and wounding or radiation and wounding. The supplemental vitamin A prevented

1984 Annals of Surgery

23415. Periconceptional vitamin supplementation and the prevention of neural tube defects in south-east England and Northern Ireland. (Full text)

Periconceptional vitamin supplementation and the prevention of neural tube defects in south-east England and Northern Ireland. A comparison has been made of the effectiveness of periconceptional vitamin supplementation for the prevention of recurrence of neural tube defects (NTD) in south-east England and Northern Ireland. These areas represent the extremes of birth prevalence of NTD (low and high respectively) within the United Kingdom. Vitamin therapy resulted in a slightly less than two-fold (...) reduction in the recurrence risk in south-east England and a greater than three-fold reduction in Northern Ireland, when compared with unsupplemented women at the same risk from the two areas. It is probable that one of the recurrences in each area did not involve the multifactorial form of NTD and, if these are excluded, then the reduction in recurrence risk with vitamin supplementation is 2.4 times in south-east England and 5.4 times in Northern Ireland. Either way, beneficial effects

1984 Journal of Medical Genetics

23416. Use of vitamin-mineral supplements by AFDC children. (Full text)

Use of vitamin-mineral supplements by AFDC children. Slightly more than 11 percent of the 1,616 children in Northern Mississippi households receiving Aid to Families with Dependent Children regularly used vitamins, according to the 540 personal interviews conducted in this study. Of the vitamins used, about 20 percent were obtained by prescription. Participation in Early and Periodic Screening, Diagnosis and Treatment (EPSDT) was found not to be related to vitamin use. The pharmacy was the main (...) source of vitamins, which most frequently were those widely advertised on television. It is suggested that pharmacists, physicians, and EPSDT personnel might take a more active role in nutrition counseling. The population is poor by definition and rural by study design. In the face of these facts, it was interesting to find that the most often used vitamin was Flintstones, one of the more expensive brands of children's vitamins. Some other vitamin products used, in descending order of frequency were

1985 Public Health Reports

23417. Recurrence rates for neural tube defects and vitamin supplementation (Full text)

Recurrence rates for neural tube defects and vitamin supplementation 7024545 1981 11 24 2018 11 13 0022-2593 18 4 1981 Aug Journal of medical genetics J. Med. Genet. Recurrence rates for neural tube defects and vitamin supplementation. 249-51 James W H WH eng Clinical Trial Journal Article Research Support, Non-U.S. Gov't England J Med Genet 2985087R 0022-2593 0 Vitamins IM Anencephaly prevention & control Clinical Trials as Topic Female Humans Neural Tube Defects genetics prevention & control (...) Pregnancy Spina Bifida Occulta prevention & control Vitamins therapeutic use 1981 8 1 1981 8 1 0 1 1981 8 1 0 0 ppublish 7024545 PMC1048725 Lancet. 1968 Sep 14;2(7568):623-6 4175169 J Med Genet. 1968 Jun;5(2):81-106 4881170 Br J Prev Soc Med. 1970 Nov;24(4):205-22 4924869 Pediatrics. 1971 Mar;47(3):577-86 4926631 Dev Med Child Neurol. 1972 Oct;14(5):626-39 4578858 J Med Genet. 1973 Sep;10(3):209-34 4590246 Dev Med Child Neurol. 1976 Oct;18(5):643-56 789160 Br Med J. 1978 Jan 14;1(6105):72-3 620202 J Med

1981 Journal of Medical Genetics

23418. Vitamin D supplements in Asian women. (Full text)

Vitamin D supplements in Asian women. 6967750 1980 11 20 2008 11 20 0007-1447 280 6220 1980 Apr 12 British medical journal Br Med J Vitamin D supplements in Asian women. 1054 Bissenden J G JG eng Journal Article England Br Med J 0372673 0007-1447 0 Ergocalciferols AIM IM Asia ethnology Ergocalciferols adverse effects Female Humans London Pregnancy Pregnancy Complications chemically induced 1980 4 12 1980 4 12 0 1 1980 4 12 0 0 ppublish 6967750 PMC1600645

1980 British medical journal

23419. Clinical trials of vitamin B6 and proline supplementation for gyrate atrophy of the choroid and retina. (Full text)

Clinical trials of vitamin B6 and proline supplementation for gyrate atrophy of the choroid and retina. Five patients with gyrate atrophy of the choroid and retina were examined ophthalmologically, especially ophthalmoscopically, to evaluate trials of vitamin B6 (pyridoxine) or supplementary proline. The oral administration of vitamin B6 was tried in two patients. The vitamin did not alter the serum ornithine level and the progression of chorioretinal atrophy in one patient (case 2). Despite (...) a reduced serum ornithine level following vitamin B6 administration, chorioretinal atrophy progressed gradually in another patient (case 3). Supplementary proline was tried in four patients. Despite the supplementation the serum proline level did not increase, and the chorioretinal atrophy progressed in one patient (case 2) who received both vitamin B6 and proline. Supplementary proline minimised the progression of gyrate atrophy in the youngest patient (case 1) and halted the progression in two others

1985 The British journal of ophthalmology

23420. Oral vitamin E supplements can prevent the retinopathy of abetalipoproteinaemia. (Full text)

Oral vitamin E supplements can prevent the retinopathy of abetalipoproteinaemia. Six patients with abetalipoproteinaemia are described who received large doses of oral vitamin E for between 12 and 18 years in addition to a low fat diet and supplements of the other fat soluble vitamins. The progressive retinopathy observed in untreated abetalipoproteinaemia was substantially modified and most probably prevented by this therapy. Angioid streaks were noted in one patient. Treatment with vitamin

1986 The British journal of ophthalmology

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