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Viral Conjunctivitis

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1. Conjunctivitis (viral, non-herpetic)

Conjunctivitis (viral, non-herpetic) Conjunctivitis (viral, non-herpetic) submit The College submit You're here: Conjunctivitis (viral, non-herpetic) Conjunctivitis (viral, non-herpetic) The CMGs are guidelines on the diagnosis and management of a range of common and rare, but important, eye conditions that present with varying frequency in primary and first contact care. Share options Aetiology Adenovirus (more than 30 serotypes) commonest form of acute infective conjunctivitis spectrum (...) , Barney NP. Conjunctivitis: a systematic review of diagnosis and treatment.JAMA. 2013;310:1721-9 Majeed A, Naeem Z, Khan DA, Ayaz A. Epidemic adenoviral conjunctivitis report of an outbreak in a military garrison and recommendations for its management and prevention. J Pak Med Assoc. 2005;55:273-5 Pihos AM. Epidemic keratoconjunctivitis: A review of current concepts in management. J Optom. 2013; 6(2): 69–74 Skevaki CL, Galani IE, Pararas MV, Giannopoulou KP, Tsakris A. Treatment of viral

2019 College of Optometrists

2. Conjunctivitis: Bacterial, Viral and Allergic

Conjunctivitis: Bacterial, Viral and Allergic Conjunctivitis: Bacterial, Viral and Allergic - medSask Home - College of Pharmacy and Nutrition - University of Saskatchewan Toggle Menu Search the U of S Search Conjunctivitis: Bacterial, Viral and Allergic Infectious or non-infectious Inflammation of the conjunctiva of one or both eyes The conjunctiva is the translucent covering of the sclera (white area) of the eye (bulbar area) and the undersurface of the eyelids (palpebral area) Infectious (...) causes Bacterial: Children : influenzae, S. pneumoniae, S. aureus Adults : aureus, coagulase-negative Staphylococcus organisms, H. influenzae, S. pneumoniae Viral – adenovirus (most common), herpes simplex virus, others Non-infectious Allergic – IgE-mediated reaction triggered by seasonal or perennial allergens Others – dry eye, contact lenses, chemical exposure, reaction to ophthalmic medications, trauma, etc. Common complaint – infectious conjunctivitis accounts for 30 to 40% of eye-related medical

2018 medSask

3. Trial to Evaluate the Efficacy and Safety of IVIEW-1201 in Acute Viral Conjunctivitis

Trial to Evaluate the Efficacy and Safety of IVIEW-1201 in Acute Viral Conjunctivitis Trial to Evaluate the Efficacy and Safety of IVIEW-1201 in Acute Viral Conjunctivitis - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before (...) adding more. Trial to Evaluate the Efficacy and Safety of IVIEW-1201 in Acute Viral Conjunctivitis The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03749317 Recruitment Status : Not yet recruiting First Posted : November 21

2018 Clinical Trials

4. Acute conjunctivitis

and antihistamines; bacterial conjunctivitis treatment includes topical antibiotics; viral conjunctivitis requires symptomatic treatment. Bacterial and viral conjunctivitis is highly contagious; measures to prevent spread of infection should be considered. Definition Conjunctivitis is the inflammation of the lining of the eyelids and eyeball caused by bacteria, viruses, allergic or immunological reactions, mechanical irritation, or medicines. American Academy of Ophthalmology. Preferred practice pattern (...) : conjunctivitis - 2013. October 2013. https://www.aao.org/preferred-practice-pattern/conjunctivitis-ppp--2013 [Figure caption and citation for the preceding image starts]: Viral conjunctivitis From the collection of Robert Sambursky, MD [Citation ends]. History and exam presence of risk factors watery discharge ropy, mucoid discharge purulent discharge itching predominant symptom eyelids stuck together in morning tender, pre-auricular lymphadenopathy conjunctival follicles superficial punctate keratopathy

2018 BMJ Best Practice

5. Ciclosporin (Verkazia) - Conjunctivitis, Keratitis

Ciclosporin (Verkazia) - Conjunctivitis, Keratitis 30 Churchill Place ? Canary Wharf ? London E14 5EU ? United Kingdom An agency of the European Union Telephone +44 (0)20 3660 6000 Facsimile +44 (0)20 3660 5555 Send a question via our website www.ema.europa.eu/contact © European Medicines Agency, 2018. Reproduction is authorised provided the source is acknowledged. 20 July 2017 EMA/505143/2017 Committee for Medicinal Products for Human Use (CHMP) Assessment report Verkazia International non (...) by an inflammation of the conjunctivitis with corneal involvement and tissue remodelling including papillae formation. It was first described by Arlt in 1846 who reported 3 cases of perilimbal swelling in young patients. The association with springtime (vernal) reflects the seasonal increase in signs and symptoms of the condition, particularly the high prevalence in hot, arid environments. Affected individuals have disease flares frequently during spring months, but can have signs and symptoms year round

2018 European Medicines Agency - EPARs

6. Conjunctivitis medicamentosa

Conjunctivitis medicamentosa Conjunctivitis medicamentosa (also Dermatoconjunctivitis medicamentosa) submit The College submit You're here: Conjunctivitis medicamentosa (also Dermatoconjunctivitis medicamentosa) Conjunctivitis medicamentosa (also Dermatoconjunctivitis medicamentosa) The CMGs are guidelines on the diagnosis and management of a range of common and rare, but important, eye conditions that present with varying frequency in primary and first contact care. Share options Aetiology (...) , but individual susceptibility to conjunctivitis medicamentosa varies widely Symptoms Initial improvement in the original condition requiring treatment Then apparent deterioration despite proper compliance with regimen Irritation, ocular pain, stinging, burning, photophobia Ocular redness Lid swelling Blurred vision Signs Diffuse punctate staining of cornea and/or conjunctiva Chronic epithelial defects (due to toxic inhibition of epithelial healing) Sometimes: corneal oedema pseudodendrites disciform stromal

2019 College of Optometrists

7. Conjunctivitis (bacterial)

Moraxella catarrhalis Predisposing factors Children and the elderly have an increased risk of infective conjunctivitis (NB Bacterial conjunctivitis in the first month of life is a serious condition that must be referred urgently to the ophthalmologist. See Clinical Management Guideline on ) contamination of the conjunctival surface superficial trauma contact lens wear (NB infection may be Gram –ve) secondary to viral conjunctivitis recent cold, upper respiratory tract infection [NB refer also (...) Conjunctivitis (bacterial) Conjunctivitis (bacterial) submit The College submit You're here: Conjunctivitis (bacterial) Conjunctivitis (bacterial) The CMGs are guidelines on the diagnosis and management of a range of common and rare, but important, eye conditions that present with varying frequency in primary and first contact care. Share options Aetiology Self-limiting bacterial infection of the conjunctiva, typically by: Staphylococcus species Streptococcus pneumoniae Haemophilus influenzae

2018 College of Optometrists

8. Viral Conjunctivitis

Viral Conjunctivitis Viral Conjunctivitis Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Viral Conjunctivitis Viral Conjunctivitis (...) Aka: Viral Conjunctivitis , Pink Eye , Adenopharyngitis Associated Conjunctivitis From Related Chapters II. Epidemiology Viral Conjunctivitis is most common cause (80% of cases) Typically spread by contaminated hands Viral sources can survive on fomites for up to 72 hours Common cause of Swimming Pool does not eliminate the virus III. Causes (most common) (more severe, ) Enterovirus Coxsackievirus (EBV, ) ( ) IV. Symptoms Mild watery or tearing Insidious onset over 36 hours Mild eye burning

2018 FP Notebook

9. Viral rash in pregnancy

in the investigation, diagnosis and management of a pregnant woman who has, or is exposed to, rash illness. A rash illness is defined as “a rash compatible with a systemic viral illness”. This guidance should be read in conjunction with more detailed PHE guidance on prophylaxis for pregnant women exposed to measles and chickenpox. This guidance is in 4 parts: the first part sets out the scope of the document and presents background information; the second part focuses on women who present with viral rash illness (...) Viral rash in pregnancy Guidance on the investigation, diagnosis and management of viral illness, or exposure to viral rash illness, in pregnancy Guidance on the investigation, diagnosis and management of viral rash illness, or exposure to viral rash illness, in pregnancy 2 About Public Health England Public Health England exists to protect and improve the nation’s health and wellbeing, and reduce health inequalities. We do this through world-leading science, knowledge and intelligence

2019 Public Health England

10. Keeping our eye on the ball for infectious conjunctivitis management

if immediate antibiotics. • Decreased by 0.9 day if delayed antibiotics. • Antibiotics were used by: 99% receiving immediate antibiotics, 53% delayed (three days), 30% no prescription. • No difference in symptom scores on days 1-3 following consultation. Context: • The two main primary care RCTs used “infectious/acute conjunctivitis” as their inclusion criteria, suggesting that making a diagnosis of bacterial conjunctivitis (versus viral) is not essential when deciding to prescribe (or not) antibiotic (...) Keeping our eye on the ball for infectious conjunctivitis management Tools for Practice is proudly sponsored by the Alberta College of Family Physicians (ACFP). ACFP is a provincial, professional voluntary organization, representing more than 4,400 family physicians, family medicine residents and medical students in Alberta. Established over sixty years ago, the ACFP strives for excellence in family practice through advocacy, continuing medical education and primary care research. www.acfp.ca

2016 Tools for Practice

11. Chronic Cough Related to Acute Viral Bronchiolitis in Children

Chronic Cough Related to Acute Viral Bronchiolitis in Children Chronic Cough Related to Acute Viral Bronchiolitis in Children CHEST Expert Panel Report Anne B. Chang, MBBS, PhD, MPH; John J. Oppenheimer, MD; Bruce K. Rubin, MD; Miles Weinberger, MD, FCCP; and Richard S. Irwin, MD, Master FCCP; on behalf of the CHEST Expert Cough Panel BACKGROUND: Acute bronchiolitis is common in young children, and some children develop chronic cough after their bronchiolitis. We thus undertook systematic (...) reviews based on key questions (KQs) using the PICO (Population, Intervention, Comparison, Outcome) format. The KQs were: Among children with chronic cough (> 4 weeks) after acute viral bron- chiolitis, how effective are the following interventions in improving the resolution of cough?: (1) Antibiotics. If so what type and for how long? (2) Asthma medications (inhaled steroids, beta 2 agonist, montelukast); and (3) Inhaled osmotic agents like hypertonic saline? METHODS: We used the CHEST expert cough

2018 American College of Chest Physicians

12. Conjunctivitis - infective

Conjunctivitis - infective Conjunctivitis - infective - NICE CKS Share Conjunctivitis - infective: Summary Infective conjunctivitis is inflammation of the conjunctiva due to viral, bacterial or parasitic infection. Viral conjunctivitis is the most common infectious conjunctivitis — the majority of cases are caused by adenoviruses. The most common bacterial causes of conjunctivitis are Streptococcus pneumoniae , Staphylococcus aureus and Haemophilus influenzae . Hyperacute conjunctivitis (...) is a rapidly developing severe conjunctivitis typically caused by infection with Neisseria gonorrhoeae. Ophthalmia neonatorum (ON) is conjunctivitis occurring within the first four weeks of life — it can be infectious or non-infectious. Acute conjunctivitis is usually self-limiting and rarely causes loss of vision. Viral conjunctivitis usually resolves within 7 days. Epidemic keratoconjunctivitis (caused by adenoviruses) can lead to visual loss and light sensitivity. Bacterial conjunctivitis typically

2018 NICE Clinical Knowledge Summaries

13. Conjunctivitis - allergic

information Definition What is it? Conjunctivitis is inflammation of the conjunctiva due to allergic or immunological reactions, infection (viral, bacterial or parasitic), mechanical irritation, neoplasia, or contact with toxic substances. The conjunctiva is a thin, transparent mucous membrane lining the anterior part of the sclera (bulbar conjunctiva) and the under-surface of the eyelids (palpebral conjunctiva). Inflammation or infection of the conjunctiva causes dilation of conjunctival vessels leading (...) , papillae and membranes. Pull on the lower eyelid and evert the upper lid to examine the palpebral conjunctiva. Follicles (small yellowish elevations of lymphocytes) can be associated with adenovirus and chlamydia. Papillae (small conjunctival elevations with central vessels) can be associated with allergic conjunctivitis and contact lens intolerance. Conjunctival membranes (yellow/white layer of fibrin adherent to underlying conjunctival tissue) can form in severe viral or bacterial infections

2017 NICE Clinical Knowledge Summaries

14. Beta-cell specific production of IL6 in conjunction with a mainly intracellular but not mainly surface viral protein causes diabetes. (PubMed)

Beta-cell specific production of IL6 in conjunction with a mainly intracellular but not mainly surface viral protein causes diabetes. Inflammatory mechanisms play a key role in the pathogenesis of type 1 and type 2 diabetes. IL6, a pleiotropic cytokine with impact on immune and non-immune cell types, has been proposed to be involved in the events causing both forms of diabetes and to play a key role in experimental insulin-dependent diabetes development. The aim of this study was to investigate (...) how beta-cell specific overexpression of IL-6 influences diabetes development. We developed two lines of rat insulin promoter (RIP)-lymphocytic choriomeningitis virus (LCMV) mice that also co-express IL6 in their beta-cells. Expression of the viral nucleoprotein (NP), which has a predominantly intracellular localization, together with IL6 led to hyperglycemia, which was associated with a loss of GLUT-2 expression in the pancreatic beta-cells and infiltration of CD11b(+) cells, but not T cells

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2014 Journal of Autoimmunity

15. Dexamethasone/Povidone Eye Drops versus Artificial Tears for Treatment of Presumed Viral Conjunctivitis: A Randomized Clinical Trial. (PubMed)

Dexamethasone/Povidone Eye Drops versus Artificial Tears for Treatment of Presumed Viral Conjunctivitis: A Randomized Clinical Trial. To determine whether topical dexamethasone 0.1%/povidone-iodine 0.4% reduces the duration of presumed viral conjunctivitis better than artificial tears and whether the treatment relieves the symptoms of this disease.Randomized, masked and controlled trial. One-hundred twenty-two patients with a clinical diagnosis of presumed viral conjunctivitis were randomized (...) -up period. Patients of the treatment group reported more stinging (p < 0.001) and a shorter conjunctivitis duration (9.4 ± 4.6 d in the dexamethasone 0.1%/povidone-iodine 0.4% group versus 11.8 ± 4.9 d in the artificial tears group, p = 0.009).The use of topical dexamethasone 0.1%/povidone-iodine 0.4% eye drops four times daily appears to reduce the duration of conjunctivitis, although it causes more stinging than artificial tears.

2014 Current eye research Controlled trial quality: uncertain

16. Artificial tears alone versus 0.45% ketorolac tromethamine with artificial tears for the treatment of acute viral conjunctivitis. (PubMed)

Artificial tears alone versus 0.45% ketorolac tromethamine with artificial tears for the treatment of acute viral conjunctivitis. To evaluate the effects of preservative-free 0.45% ketorolac tromethamine and artificial tears (carboxymethylcellulose) compared with those of preservative-free artificial tears alone on the symptoms and signs of acute viral conjunctivitis.This was a randomized, double-masked clinical trial that included 50 patients who were diagnosed with acute viral conjunctivitis (...) segment examination.Both groups showed an improvement in the signs and symptoms of conjunctivitis in their follow-up visits. There was no significant difference in symptom and sign scores between Group 0 and Group 1 in the study visits (p>0.05). The frequency of side effects during treatment was similar between groups (p>0.05).Our findings indicate that 0.45% ketorolac tromethamine was not superior to the use of artificial tears in relieving the signs and symptoms of viral conjunctivitis.

2014 Arquivos brasileiros de oftalmologia Controlled trial quality: uncertain

17. A Clinical Trial of Reproxalap in Subjects With Seasonal Allergic Conjunctivitis Using the Environmental Exposure Chamber

allergic conjunctivitis based on principal investigator's judgement have a positive skin prick test to ragweed pollen within the past year of screening Exclusion Criteria: known contraindication or hypersensitivities to any components of the investigational product medication or components history of uveitis, blepharitis, dry eye syndrome, herpes simplex keratitis, or herpes zoster keratitis; presence of any ocular infection (bacterial, viral, or fungal) or active ocular inflammation (e.g., follicular (...) A Clinical Trial of Reproxalap in Subjects With Seasonal Allergic Conjunctivitis Using the Environmental Exposure Chamber A Clinical Trial of Reproxalap in Subjects With Seasonal Allergic Conjunctivitis Using the Environmental Exposure Chamber - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum

2018 Clinical Trials

18. A Methodology Development Environmental Clinical Trial of Reproxalap in Subjects With Seasonal Allergic Conjunctivitis

A Methodology Development Environmental Clinical Trial of Reproxalap in Subjects With Seasonal Allergic Conjunctivitis A Methodology Development Environmental Clinical Trial of Reproxalap in Subjects With Seasonal Allergic Conjunctivitis - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum (...) number of saved studies (100). Please remove one or more studies before adding more. A Methodology Development Environmental Clinical Trial of Reproxalap in Subjects With Seasonal Allergic Conjunctivitis The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details

2018 Clinical Trials

19. Efficacy of the Ophthalmic Pazufloxacin 0.6% for Bacterial Conjunctivitis, Compared to Gatifloxacin 0.3%.

the study. Users of any formulation with ophthalmic application, including lubricants, that can not, or do not want to suspend it during the study. Antecedents of eye surgery 6 weeks prior to study entry. Viral or allergic conjunctivitis. Active uveitis. Active ulcerative keratitis. Recurrent corneal erosion syndrome Antecedent of hypersensitivity or allergy to fluoroquinolones. Contacts and Locations Go to Information from the National Library of Medicine To learn more about this study, you or your (...) Efficacy of the Ophthalmic Pazufloxacin 0.6% for Bacterial Conjunctivitis, Compared to Gatifloxacin 0.3%. Efficacy of the Ophthalmic Pazufloxacin 0.6% for Bacterial Conjunctivitis, Compared to Gatifloxacin 0.3%. - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100

2018 Clinical Trials

20. Photo Rounds: Painful facial blisters, fever, and conjunctivitis. (PubMed)

Photo Rounds: Painful facial blisters, fever, and conjunctivitis. Following Tx for facial blisters, our patient returned with what appeared to be viral conjunctivitis. Further evaluation revealed a missed tip-off to the proper Dx.

2018 Journal of Family Practice

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