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Vecuronium

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161. Postoperative Respiratory Failure in a Patient with Undiagnosed Myastenia Gravis Full Text available with Trip Pro

Postoperative Respiratory Failure in a Patient with Undiagnosed Myastenia Gravis Myasthenia gravis (MG) is an autoimmune disease caused by the development of antibodies against the nicotinic acetylcholine receptor. There is hypersensitivity against non-depolarizing muscle relaxants in these patients. Sugammadex eliminates the effects of steroid non-depolarizing muscle relaxants, such as rocuronium and vecuronium, by selectively encapsulating their molecules. In this case report, we present

2016 Turkish journal of anaesthesiology and reanimation

162. Comparison of Leg Elevation and Leg Wrapping in the Prevention of Propofol Induced Hypotension

will be given by inj fentanyl 2µg/kg body weight. Lower limbs will be neither elevated or wrapped. Vitals will be recorded again. 3 minutes of pre-oxygenation will be done. Anaesthesia will be induced with inj. propofol 2mg/kg body weight injected over 30 seconds. Muscle relaxation will be achieved by inj. vecuronium 0.1mg/kg body weight. Patient will be ventilated with oxygen for 5 minutes. Orotracheal intubation will be performed with appropriate sized endotracheal tube. Other: control no intervention has (...) . vecuronium 0.1mg/kg body weight. Patient will be ventilated with oxygen for 5 minutes. Orotracheal intubation will be performed with appropriate sized endotracheal tube. Stand will be removed and legs will be brought to horizontal position 10 minutes after intubation. Other: leg elevation A stand making an angle of 30 degree to the horizontal is used to elevate both the legs Experimental: Group W Leg wrapping Patient will be shifted to operation theatre. Crystalloids at 100ml/hr will be given. Analgesia

2016 Clinical Trials

163. Rapid Sequence Induction Czech Republic: Survey

for induction (order with the number in the row) - propofol, etomidate, ketamine, thiopental, midazolam, suxamethonium, rocuronium, cisatracurium, atracurium, vecuronium Manual hand-bag ventilation after induction: with limited pressure/contraindicated Airway: tracheal tube with the cuff/without cuff/laryngeal mask Comments Study Design Go to Layout table for study information Study Type : Observational Actual Enrollment : 164 participants Observational Model: Other Time Perspective: Prospective Official

2016 Clinical Trials

164. Transversus Abdominis Plane Block in Iliac Crest harvest-is it Beneficial?

excluded from the study. Patients undergoing revision surgeries were also excluded from the study. All the candidates were randomly alloted to either of the two groups, using a computer - generated number. All the patients were premedicated with Midazolam 0.15mg kg-1 and Glycopyrolate 0.01mg kg-1 Anaesthesia was induced with Propofol 2 mg kg -1 and Fentanyl 2 mcg kg-1 .Vecuronium 0.1 mg kg-1 was given to facilitate orotracheal intubation with a cuffed tube.Anaesthesia was maintained with oxygen

2016 Clinical Trials

165. Magnesium Sulfate Effect Following the Reversal of Neuromuscular Blockade Induced by Rocuronium With Sugammadex

Neuromuscular Blockade Drug: Magnesium Sulfate Drug: Saline Phase 4 Detailed Description: Sugammadex is a novel neuromuscular blocking reversal agent. Its mechanism of action is the encapsulation of rocuronium and vecuronium molecules. Numerous studies show a potential role of magnesium in reducing anesthetic requirements, sympathetic response to surgical trauma, antinociceptive action and neuroprotective effects. However, its use is limited because magnesium potentiates non-depolarizing neuromuscular

2016 Clinical Trials

166. Effects of Esmolol on the Prevention of Haemodynamic Responses to Tracheal Extubation after Craniotomy Operations. Full Text available with Trip Pro

in either the Group Esmolol (n=15) or the Group Control (n=15). Anaesthesia was induced with 5-7 mg kg(-1) thiopental sodium, 1 μg kg(-1) remifentanil, and 0.1 mg kg(-1) vecuronium bromide iv, and was maintained with 1 MAC sevoflurane in oxygen-air mixture (50:50) and 0.25 μg kg(-1) min(-1) remifentanil infusion. At the end of the operation, patients inhaled 100% oxygen after the discontinuation of the anaesthetic agents. For Group Esmolol, 5 min before extubation 2 mg kg(-1) esmolol in 50 mL

2016 Turkish journal of anaesthesiology and reanimation Controlled trial quality: uncertain

167. Cognitive Dysfunction Following Cardiac Surgery

were randomized into two groups to receive either intravenous dexamethasone 0.1 mg/kg or the same volume of normal saline i.v. 10 hours before the surgery. Random sequence generator was used to determine participant allocation. Anesthesia in all patients was based on fentanyl, midazolam, vecuronium and sevoflurane. The depth of anesthesia was monitored using bispectral index (BIS). During cardiopulmonary bypass alpha-stat technique was used with the maintenance of normothermia (35.5-36.5°C

2016 Clinical Trials

168. Comparison of Two Methods of Strain by Perioperative Transesophageal Echo in CABG : An Observational Study

anaesthesia technique will be used for all the patients. Inside the operating room, electrocardiography (ECG), pulse oximetry and noninvasive blood pressure (NIBP) will be applied. Anaesthesia will be induced with fentanyl 5 - 10 µg/kg/ body weight and propofol titrated to loss of response to verbal commands followed by endotracheal intubation facilitated by vecuronium 0.1mg/kg. A 20 gauge arterial catheter will be inserted in left radial artery and right internal jugular vein will be cannulated (...) with triple lumen catheter for central venous access and pulmonary artery catheter for haemodynamic assessment. A baseline transthoracic echocardiogram will be performed after induction of general anaesthesia. After induction of general anaesthesia , a TEE probe (GE Medical Systems, Horten, Norway) will be introduced. Anaesthesia will be maintained by isoflurane, intravenous morphine (intermittent boluses; total 0.5 mg/kg during surgery) and vecuronium boluses. All patients will undergo CABG under

2016 Clinical Trials

169. Sugammadex/Neostigmine and Liver Transplantation

at the neuromuscular junction. The administration of neostigmine may however cause bronchospasm, abdominal pain, nausea, cardiac arrhythmias and can not be used if the neuromuscular blockade is deep. Recently the use of sugammadex, a new drug that can act as an antidote to a comparison of non-depolarizing muscle relaxants amino-steroidal (rocuronium, vecuronium) showed good clinical impact. This drug works by encapsulating the muscle relaxant molecule in the plasma with a high affinity and binding to the complex

2016 Clinical Trials

170. Studies of Application of Combined General Anesthesia and Bilateral TPVB in OPCABG

of anesthesia; Fast channel anesthesia • Induction use Sufentanil 0.5~1ug/kg, Vecuronium for Injection 0.15mg/kg and Etomidate 0.2~0.6mg/kg; ②. Maintain use Sufentanil Hydrochloride for Injection 0.01~0.04ug/kg•min, Sevoflurane 0.5~1.5MAC(minimum alveolar concentration) and Infusing Dexmedetomidine which load dose 0.5μg/kg in 10min then changed into 0.5-1.0μg/kg•h,Vecuronium 0.06~0.12mg/kg•h; ③. Intravenous hydromorphone Hydrochloride Injection 0.15mg/kg before surgery over. Experimental: TPVB T3/4+GA (...) : Lung protection measure during the surgery(Dräger Primus) Protective ventilation strategy(Low tidal volume about 6~7ml/kg, joint use of PEEP) Drug: Anesthesia drugs during the surgery Bilateral thoracic paravertebral block before induction of anesthesia; Fast channel anesthesia • Induction use Sufentanil 0.5~1ug/kg, Vecuronium for Injection 0.15mg/kg and Etomidate 0.2~0.6mg/kg; ②. Maintain use Sufentanil Hydrochloride for Injection 0.01~0.04ug/kg•min, Sevoflurane 0.5~1.5MAC(minimum alveolar

2016 Clinical Trials

171. Effect of Acetazolamide on Optic Nerve Sheath Diameter in Laparoscopic Donor Nephrectomies

: Normal Saline Not Applicable Detailed Description: this study was done on 40 American Society of Anaesthesiologist(ASA) I & II live donors of either sex in adult age group undergoing laparoscopic live donor nephrectomy. After getting approval from institutes ethical committee and written informed consent, Donors were randomly allocated to either of two group. Anaesthesia was induced with injection morphine 0.1 mg/kg, injection propofol 1-2 mg/kg and vecuronium 0.1 mg/kg. Maintenance of anaesthesia

2016 Clinical Trials

172. Segmental Epidural Anesthesia (SEA) V/S General Anesthesia for PCNL

. Atropine 0.06 mg intramuscularly half an hour prior to surgery, IV ranitidine 1mg kg-1, IV ondansetron 0.08mg kg-1 IV midazolam 0.02mg kg-1 and Pentazocine 0.3 mg/kg. Anaesthesia was induced with IV Thiopentone sodium 3-5 mg kg-1 and Vecuronium 0.1mg kg-1.and then intubated. Anaesthesia was maintained on 50 %:50% nitrous oxide and oxygen, vecuronium and propofol infusion . At the end of the surgery postoperative analgesia was given with IV tarmadol and local nfiltration with 0.25% bupivacaine

2016 Clinical Trials

173. A Unique Device for Independent Lung Ventilation

for neuromuscular blockade, and bronchial intubation with a Robertshow double lumen tube was performed. The left bronchus was intubated for right lung surgery, and the right bronchus was intubated for left lung surgery. Tube placement was checked via auscultation and fiberscope. Anaesthesia was maintained with sevoflurane, additional fentanyl doses were used if needed, and neuromuscular blockade was obtained with vecuronium 0.1 mg kg-1. Additionally, 0.1 mg kg-1 dose of morphine was given subcutaneously

2016 Clinical Trials

174. Comparison of Onset and Duration of Rocuronium Between 2nd Trimester Pregnant and Non-pregnant Women

to the following factors; Increase in plasma volume, heart rate and cardiac output; decrease in blood pressure due to decrease of systemic resistance and relative decrease of hepatic circulation and the aggravation of hepatic dysfunction. These changes intensify as pregnancy progresses into the 3rd trimester and take their effect on the onset time and duration of muscle relaxants. Rocuronium and the steroidal non-depolarizing muscle relaxant like vecuronium is mostly excreted with bile by hepatic metabolism (...) and classified as the FDA pregnancy category B, and is widely used in general anesthesia of pregnant women. Previous studies reported onset time of rocuronium is affected by cardiac output, blood circulation time of the whole body, and muscle perfusion. Accordingly, many researches were conducted under the assumption of onset time and duration being affected by physiologic changes during pregnancy. For example, in the research where vecuronium was used as muscle relaxant for pregnant woman undergoing C-sec

2016 Clinical Trials

175. Incidence of postoperative nausea and vomiting following gynecological laparoscopy: A comparison of standard anesthetic technique and propofol infusion. Full Text available with Trip Pro

) controlled trial.Operation theater, postanesthesia recovery room, teaching hospital.Sixty ASA (American Society of Anesthesiologists) I and II female patients (aged 20-60 years) scheduled for gynecological laparoscopy were included in the study.Patients in Group A received standard anesthesia with thiopentone for induction and maintenance with isoflurane-fentanyl, and those in Group B received propofol for induction and maintenance along with fentanyl. All patients received nitrous oxide, vecuronium

2016 Acta anaesthesiologica Taiwanica : official journal of the Taiwan Society of Anesthesiologists Controlled trial quality: uncertain

176. Feasibility of monitoring stress using skin conduction measurements during intubation of newborns. Full Text available with Trip Pro

Feasibility of monitoring stress using skin conduction measurements during intubation of newborns. The objective of this study was to assess the feasibility of monitoring stress responses in newborns during naso-tracheal intubation after two different premedication regimens, using skin conductance measurements (SCM). Twenty-two newborns were randomised and premedicated with morphine + vecuronium or propofol. SCM (peaks/s) were collected prior to, during and after the procedure. Threshold (...) for interpreting responses as stressful was 0.21 peaks/s. Intubation conditions and physiological parameters were registered. Intubation conditions were good in all newborns. Administration of morphine (range 1.4-10.3 min) before administration of vecuronium did not affect SCM when a stressful stimulus was applied. Within 1.6 min (range 0.8-3 min) after administration of vecuronium, SCM disappeared in 10 of 11 newborns. Propofol reduced SCM in 10 of 11 newborns at the first attempt. Further attempts were

2016 European journal of pediatrics Controlled trial quality: uncertain

177. To study the effect of injection dexmedetomidine for prevention of pain due to propofol injection and to compare it with injection lignocaine. Full Text available with Trip Pro

and isoflurane on intermittent positive pressure ventilation with Bain's circuit and inj. vecuronium was used as muscle relaxant.Demographic data showed that there was no statistically significant difference between the 2 groups. There was no statistically significant difference between 2 groups in respect to inj. propofol pain. No adverse effects like oedema, pain, wheal response at the site of injection were observed in the two groups.Copyright © 2013 Sociedade Brasileira de Anestesiologia. Published

2015 Brazilian journal of anesthesiology (Elsevier) Controlled trial quality: uncertain

178. [To study the effect of injection dexmedetomidine for prevention of pain due to propofol injection and to compare it with injection lignocaine]. Full Text available with Trip Pro

and isoflurane on intermittent positive pressure ventilation with Bain's circuit and inj. vecuronium was used as muscle relaxant.Demographic data showed that there was no statistically significant difference between the 2 groups. There was no statistically significant difference between 2 groups in respect to inj. propofol pain. No adverse effects like oedema, pain, wheal response at the site of injection were observed in the two groups.Copyright © 2013 Sociedade Brasileira de Anestesiologia. Publicado por

2015 Revista brasileira de anestesiologia Controlled trial quality: uncertain

179. [Lidocaine in endotracheal intubation]. (Abstract)

[Lidocaine in endotracheal intubation]. To evaluate the effect of lidocaîne use by IV during endotracheal intubation.Our study was simple insu randomized prospective and comparative. It was done at the teaching hospital Gabriel Touré of Bamako from march to September 2005. Patients were distributed in 3 groups. The first group I: got fentanyl 2 nmg /kg+penthotal 5mg/kg+vecuronium 0.1mg/kg and intubation 3 mn later. The group II: lodocaîne 1,5mg +fentanyl 2nmg/kg+penthotal 5mg /kg + vecuronium (...) 0.1mg/kg and intubation 3mn later. The group III: lodocaïne 1.5 mg/kg+pentothal 5mg/kg+vecuronium 0.1mg/kg and intubation 3 mn later.The mean arterial pression to intubation has been 105.88±13.82 mmhg in the groupI, 96.60±15.01mmhg in the group II and 96.44±12.09mmhg in the group III with P = 0.008. To incision it has been 99.12±11.82 in the group I, 94.90 ±6.67 mmhg in the group II and 92.26±8.81 mmhg in the groupIII with P = 0.017.Lidocaïne, used alone in Iv or associated to fentanyl 3 mn before

2015 Le Mali medical Controlled trial quality: uncertain

180. Intraoperative anaphylaxis to neuromuscular blocking agents: the incidence over 9 years at two tertiary hospitals in South Korea: A retrospective observational study. (Abstract)

reaction was determined from both clinical signs and the results of skin tests.Over 9 years, 729 429 patients were exposed to NMBA, the most frequently used being rocuronium [425 047 (58.3%)] and vecuronium [274 801 (37.7%)]. The overall incidence of intraoperative anaphylaxis was 2.6 per 100 000 (19 cases), and was higher with rocuronium (16 cases, 3.8 per 100 000) than with vecuronium (two cases, 0.7 cases per 100 000), P = 0.014. Comparing the first 3 years with the last 6 years, the incidence

2015 European Journal of Anaesthesiology

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