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Vecuronium

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161. Segmental Epidural Anesthesia (SEA) V/S General Anesthesia for PCNL

. Atropine 0.06 mg intramuscularly half an hour prior to surgery, IV ranitidine 1mg kg-1, IV ondansetron 0.08mg kg-1 IV midazolam 0.02mg kg-1 and Pentazocine 0.3 mg/kg. Anaesthesia was induced with IV Thiopentone sodium 3-5 mg kg-1 and Vecuronium 0.1mg kg-1.and then intubated. Anaesthesia was maintained on 50 %:50% nitrous oxide and oxygen, vecuronium and propofol infusion . At the end of the surgery postoperative analgesia was given with IV tarmadol and local nfiltration with 0.25% bupivacaine

2016 Clinical Trials

162. Sugammadex at both high and low doses does not affect the depth of anesthesia or hemodynamics: a randomized double blind trial. (PubMed)

Sugammadex at both high and low doses does not affect the depth of anesthesia or hemodynamics: a randomized double blind trial. Previous studies have shown that sugammadex decreases the anesthetic depth when administered to reverse the neuromuscular blockade produced by rocuronium/vecuronium. The aim of the present study was to investigate the effect of sugammadex alone on anesthetic depth and hemodynamics. Sixty patients scheduled for abdominal surgery participated in the study. Anesthesia

2016 Journal of clinical monitoring and computing

163. Comparison of intravenous labetalol and bupivacaine scalp block on the hemodynamic and entropy changes following skull pin application: A randomized, open label clinical trial. (PubMed)

procedures were randomized into two groups, L (labetalol) and B (bupivacaine) of 33 each. After a standard induction sequence using fentanyl, propofol and vecuronium, patients were intubated. Baseline hemodynamic parameters and entropy levels were noted. Five minutes before, application of the pins, group L patients received IV labetalol 0.25 mg/kg and group B patients received scalp block with 30 ml of 0.25% bupivacaine. Following application of the pins, heart rate (HR), systolic arterial pressure (SAP

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2016 Asian journal of neurosurgery

164. [Neuromuscular monitoring during anesthesia.]. (PubMed)

prolapse given muscle relaxants during anesthesia were studied, randomly allocated to four groups. Fourty of these patients were monitored with neuromuscular monitor (TOF-guard") during anesthesia and the set point was a TOF-ratio of at least 70% before extubating the patients. Fourty patients were monitored by usual clinical signs (spontaneus breathing, cough and muscle movement). Twenty patients in each group were given vecuronium as muscle relaxant and 20 patients recieved pancuronium, again

2015 Laeknabladid

165. Voxel-Based Morphometry in Epileptic Baboons: Parallels to Human Juvenile Myoclonic Epilepsy (PubMed)

scans using a 3T Siemens TIM Trio (Siemens, Erlangen, Germany) were available in 107 baboons (67 females; mean age 16±6years) with documented clinical histories and scalp-electroencephalography (EEG) results. For neuroimaging, baboons were anesthetized with isoflurane 1% (1-1.5 MAC) and paralyzed with vecuronium (0.1-0.3mg/kg). Data processing and analysis were performed using FSL's VBM toolbox. GMC was compared between CTL and SZ+ baboons, epileptic baboons with interictal epileptic discharges

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2016 Epilepsy research

166. Sugammadex for the reversal of muscle relaxation in general anaesthesia: a systematic review and economic assessment.

Sugammadex for the reversal of muscle relaxation in general anaesthesia: a systematic review and economic assessment. Sugammadex (Bridion) is a newly developed agent for the reversal of neuromuscular blockade (NMB) induced by rocuronium or vecuronium. Sugammadex can reverse profound blockade and can be given for immediate reversal and its use would avoid the potentially serious adverse effects of the currently used agent, succinylcholine. Also, sugammadex can reverse NMB more quickly (...) to > 90 minutes for rocuronium + placebo, and 49 minutes for rocuronium + neostigmine. Results for vecuronium were similar. In addition, recovery from NMB was faster with rocuronium reversed by sugammadex 16 mg/kg after 3 minutes (immediate reversal) than with succinylcholine followed by spontaneous recovery (median time to primary outcome 4.2 versus 7.1 minutes). The evidence base for modelling cost-effectiveness is very limited. However, assuming that the reductions in recovery times seen

2016 Health technology assessment (Winchester, England)

167. Retrospective Evaluation of Patients who Underwent Laparoscopic Bariatric Surgery (PubMed)

in anaesthesia and analgesia, the duration of recovery unit/hospital stay, intensive care unit/mechanical ventilation requirements and complications were recorded.A total of 329 ASA II-III patients over a 3-year period were operated. Thiopental and propofol were administered at induction, sevoflurane, isoflurane and desflurane were administered for the maintenance, and vecuronium and rocuronium were administered to aid in neuromuscular blockage. The mean durations of recovery unit and hospital stays were

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2018 Turkish journal of anaesthesiology and reanimation

168. Effects of Premedication on Heart Rate Variability at Induction of Anaesthesia: Comparison between Midazolam and Hydroxyzine (PubMed)

was facilitated with vecuronium 0.15 mg kg-1. Blood pressure, heart rate and HRV were measured at predetermined time points for 10 min after intubation.Systolic blood pressure and heart rate significantly increased after intubation in both groups and the increase was greater in the hydroxyzine group. The high frequency (HF) component decreased significantly in both groups, and no difference was found between the two groups. The low frequency component/HF ratio significantly increased in the hydroxyzine group

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2018 Turkish journal of anaesthesiology and reanimation

169. Massive ST Elevation After V Fib Arrest, Discordant Bedside Echo Results

and needing time to drive in. She was beginning to move all extremities, so she received propofol and vecuronium. In spite of propofol, she remained very hypertensive. A nitroglycerine drip was started and titrated up to control BP. She underwent placement of an intravascular cooling catheter for targeted temperature management. Before the BP was completely controlled, and just before transferring the the cath lab, this ECG was recorded 46 minutes after the first.: All STE is resolved. The angiogram

2014 Dr Smith's ECG Blog

170. Bridion (sugammadex sodium)

in the reversal of neuromuscular blockade induced by rocuronium bromide or vecuronium bromide have been demonstrated. However, the efficacy and safety of the proposed product have been evaluated using foreign clinical data, based on the results from 2 bridging studies for routine reversal of shallow (at the reappearance of T 2 [the second twitch in response to train-of-four (TOF) stimulation], as detected with a neuromuscular monitor) and profound (at 1-2 PTCs [1-2 post-tetanic counts] [1-2 responses to post (...) with impaired renal or hepatic function, geriatric patients, children, and pregnant women/nursing mothers. It is also necessary to investigate the influences of the neuromuscular blocking agent used (rocuronium bromide or vecuronium bromide), the level of neuromuscular blockade to be reversed by the proposed product, and the use of a neuromuscular monitor on the efficacy and safety of the proposed product, and the details of administration and the safety of the proposed product when it had to be re

2010 Pharmaceuticals and Medical Devices Agency, Japan

171. Bacterial Contamination of Anaesthetic and Vasopressor Drugs in the Operating Theatres: Ameliyathanelerde Anestetik ve Vazopressör İlaçların Bakteriyel Kontaminasyonu (PubMed)

, vecuronium and ephedrine, from 20 operating rooms and refrigerators where the unused drugs were stored. Each drug was divided into two groups, the pre-use group and the post-use group. The pre-use drugs were cultured before the patient received the drug. The post-use drugs were cultured after the patient had received the drug or after the drugs had been transferred to other syringes. The culture results were reported as either positive or negative.Out of the 945 drug samples, 26 (2.8%, 95% confidence (...) interval=1.8%-4.0%) gave a positive culture. Of the 317 propofol samples, 20 (6.3%) were found to have bacterial contamination, 11 in the pre-use group and 9 in the post-use group. Of the 318 ephedrine samples, 6 (1.9%) were found to be positive on culture, one in the pre-use group and five in the post-use group. Vecuronium gave no positive cultures. All organisms were non-pathogenic, and no fungal contamination was found.The incidence of bacterial contamination in anaesthetic and vasopressor drugs

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2017 Turkish journal of anaesthesiology and reanimation

172. Neostigmine Methylsulfate Injection, USP

, p. 712 of article) 99 Table 16 Calculated effective doses of neostigmine for 50% (ED 50 ) and 80% (ED 80 ) recovery of the TOF in children and adults (based on Table 2, p. 712 of article) 100 Table 17. Summary of study findings 102 Table 18. Mean TH and TOF values at 15 minutes after neostigmine administration (from Table 1 on p. 576 of article) 105 Table 19. Recovery times from Rocuronium and Vecuronium after Neostigmine administration (based on tables 3 and 4 in the article) 108 Table 20 (...) . Summary of the Caldwell et al. study results 111 Table 21. TOF ratios at different times following vecuronium and neostigmine administration (Table 2 on p. 1170 of the article) 114 Table 22. Summary of pharmacodynamic effects of neostigmine for patients with normal renal function (NL) and end-stage renal disease (RF) [mean (SD)] (based on Table 1 on p. 135 of the article) 117 Reference ID: 3187027Clinical Review Arthur Simone, MD, PhD NDA 203629 Neostigmine Sulfate Injection, USP 6 Table 23. Time

2014 FDA - Drug Approval Package

173. Determining brain death in adults

intoxication, high cervical spinal cord injury, lidocaine toxicity, baclofen overdose, and delayed vecuronium clearance. The description of the examinations provided in these studies indicated that a complete brain death examination was not performed in any of these patients. We found no reports in peer-reviewed medical journals of recovery of brain function after a determination of brain death using the AAN practice parameter. Conclusion. In adults, recovery of neurologic function has not been reported (...) J Neurol Sci 2003 ; 30 : 397 –404. Joshi MC, Azim A, Gupta GL, Poddar BP, Baronia AK, Singh RK. Guillain-Barré syndrome with absent brainstem reflexes: a report of two cases. Anaesth Intensive Care 2008 ; 36 : 867 –869. Kainuma M, Miyake T, Kanno T. Extremely prolonged vecuronium clearance in a brain death case. Anesthesiology 2001 ; 95 : 1023 –1024. Wijdicks EFM. Brain death worldwide: accepted fact but no global consensus in diagnostic criteria. Neurology 2002 ; 58 :20–25. Saposnik G, Bueri JA

2010 American Academy of Neurology

174. Effects of Esmolol on the Prevention of Haemodynamic Responses to Tracheal Extubation after Craniotomy Operations. (PubMed)

in either the Group Esmolol (n=15) or the Group Control (n=15). Anaesthesia was induced with 5-7 mg kg(-1) thiopental sodium, 1 μg kg(-1) remifentanil, and 0.1 mg kg(-1) vecuronium bromide iv, and was maintained with 1 MAC sevoflurane in oxygen-air mixture (50:50) and 0.25 μg kg(-1) min(-1) remifentanil infusion. At the end of the operation, patients inhaled 100% oxygen after the discontinuation of the anaesthetic agents. For Group Esmolol, 5 min before extubation 2 mg kg(-1) esmolol in 50 mL

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2016 Turkish journal of anaesthesiology and reanimation

175. Postoperative Respiratory Failure in a Patient with Undiagnosed Myastenia Gravis (PubMed)

Postoperative Respiratory Failure in a Patient with Undiagnosed Myastenia Gravis Myasthenia gravis (MG) is an autoimmune disease caused by the development of antibodies against the nicotinic acetylcholine receptor. There is hypersensitivity against non-depolarizing muscle relaxants in these patients. Sugammadex eliminates the effects of steroid non-depolarizing muscle relaxants, such as rocuronium and vecuronium, by selectively encapsulating their molecules. In this case report, we present

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2016 Turkish journal of anaesthesiology and reanimation

176. Once Daily Metronidazole for Perforated Appendicitis

in the last 14 days, prior to the current admission for appendicitis Patients already taking any of the following medications at admission (as these may interact with Metronidazole as stated in the product monograph): disulfiram, oral anticoagulant therapy (warfarin type), phenytoin or phenobarbital, vecuronium, lithium, busulfan The physician elects to treat the patient conservatively (non-surgically) Contacts and Locations Go to Information from the National Library of Medicine To learn more about

2015 Clinical Trials

177. Impact of iv Dexamethasone on Reversal of Rocuronium-induced Neuromuscular Block by Sugammadex

Posted : July 21, 2017 Sponsor: Centre Hospitalier Universitaire Vaudois Information provided by (Responsible Party): Eric Albrecht, Centre Hospitalier Universitaire Vaudois Study Details Study Description Go to Brief Summary: Sugammadex is used as a reversal drug for rocuronium- or vecuronium-induced neuromuscular block during general anaesthesia. IV dexamethasone is injected as a prophylactic measure against postoperative nausea and vomiting. Recent animal data have shown that dexamethasone may

2015 Clinical Trials

178. Naloxone for Optimizing Hypoxemia Of Lung Donors

hypoxemia (PFR - PaO2 divided by FiO2, on positive end-expiratory pressure [PEEP] of 5 and usually 100% FiO2). Naloxone and placebo will both be co-administered with a neuromuscular blocking agent (e.g. vecuronium, per center protocol) to obviate any increase in spinal reflex movements that may be potentiated by naloxone treatment. All other protocols for organ donor management should be maintained at each OPO and no other study interventions are required. Transplant centers will be informed (through

2015 Clinical Trials

179. Influence of Cardiopulmonary Bypass, and Sevoflurane or Propofol Anesthesia, on Tissue Oxygen Saturation.

weaning of CPB. Procedure: General anaesthesia with propofol use Premedication: lorazepam 50 μg kg-1, omeprazole 40 mg, and metoprolol 12.5 mg one hour before transport to the operating theatre. Anaesthesia induction: 0.2 mg fentanyl, 0.3 mg/kg, etomidate, and vecuronium bromide 0.1 mg/kg for muscle relaxation, followed by a continuous infusion at the rate of 0.05 mg/kg/h until the sternum closure. Intraoperative analgesia: fentanyl in fractions, up to the total dose of 20-30 μg/kg. Maintenance (...) -clamp, 45 minutes after weaning of CPB. Procedure: General anaesthesia with sevoflurane use Premedication: lorazepam 50 μg kg-1, omeprazole 40 mg, and metoprolol 12.5 mg one hour before transport to the operating theatre. Anaesthesia induction: 0.2 mg fentanyl, 0.3 mg/kg, etomidate, and vecuronium bromide 0.1 mg/kg for muscle relaxation, followed by a continuous infusion at the rate of 0.05 mg/kg/h until the sternum closure. Intraoperative analgesia: fentanyl in fractions, up to the total dose of 20

2015 Clinical Trials

180. The Effect of TEAS on the Quality of Early Recovery

) on the quality of early recovery in the patients undergoing gynecological laparoscopic surgery. Condition or disease Intervention/treatment Phase C.Delivery; Surgery (Previous), Gynecological Inappropriate Device Stimulation of Tissue Delayed Emergence From Anesthesia Other: TEAS Other: Con Drug: propofol, remifentanil, vecuronium Other: mechanical ventilation Not Applicable Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Actual Enrollment : 60 participants (...) by the National Library of Medicine available for: Arms and Interventions Go to Arm Intervention/treatment TEAS Group TEAS consisted of 30 min of stimulation (12-15 mA, 2/100 Hz) at the Hegu (L14) and Neiguan (PC6) before anesthesia. Anesthesia was induced i.v. with propofol (2 mg kg-1) and remifentanil (1 μg kg-1) using a target-controlled infusion (TCI) system. After loss of consciousness, vecuronium (0.1 mg kg-1) was administered i.v. Patients' lungs were mechanically ventilated in a volume-controlled mode

2015 Clinical Trials

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