How to Trip Rapid Review

Step 1: Select articles relevant to your search (remember the system is only optimised for single intervention studies)

Step 2: press

Step 3: review the result, and maybe amend the or if you know better! If we're unsure of the overall sentiment of the trial we will display the conclusion under the article title. We then require you to tell us what the correct sentiment is.

1,410 results for

Vecuronium

by
...
Latest & greatest
Alerts

Export results

Use check boxes to select individual results below

SmartSearch available

Trip's SmartSearch engine has discovered connected searches & results. Click to show

101. Effect of Type II Diabetes Mellitus With Neuropathy on the Clinical Use of Rocuronium

during anesthesia maintenance. In a series of studies, vecuronium has been the only agent investigated in patients with diabetes mellitus and other diseases characterized by neuromuscular dysfunction. Delayed recovery from the neuromuscular block after vecuronium administration was shown in patients with diabetes mellitus. Currently, rocuronium, with its rapid onset of action, rapid recovery profile and inactive metabolites, is generally known as a safe agent for anesthesia under normal conditions

2018 Clinical Trials

102. An Observational Study of Cerebral Blood Flow Velocity Evaluation in the Prone Position During Posterior Lumbar Surgery. (Abstract)

Doppler ultrasonography to evaluate the effect of the PP on cerebral hemodynamics.Twenty-two patients undergoing spine surgery in the PP were studied. General anesthesia was induced using 250 μg of fentanyl, 2 mg/kg of propofol, and 0.1 mg/kg of vecuronium, and was maintained with 0.25%-0.5% isoflurane, 50% nitrous oxide in oxygen, continuous infusion of 100 μg/kg/min of propofol, 1.5 μg/kg/h of fentanyl, and 0.15 mg/kg/h of ketamine. Continuous invasive arterial blood pressure, heart rate

2018 Anesthesia and Analgesia

103. Is lower-dose sugammadex a cost-saving strategy for reversal of deep neuromuscular block? Facts and fiction. Full Text available with Trip Pro

as a potential cost-saving strategy are discussed.Reversal of neuromuscular block is important to accelerate the spontaneous recovery of neuromuscular function. Sugammadex is able to reverse a rocuronium- or vecuronium-induced neuromuscular block rapidly and efficiently from every depth of neuromuscular block. However, since sugammadex was introduced in clinical anesthesia, several studies have reported administration of a lower-than-recommended dose of sugammadex. The decision to under-dose sugammadex

2018 BMC Anesthesiology

104. Anesthetic Methods and Gene Expression Profile

in the GA-group received general anesthesia. GA was induced by intravenous fentanyl (1 mcg/kg) and propofol (2 mg/kg), followed by vecuronium bromide (0.1 mg/kg) to facilitate tracheal intubation, then GA was maintained using a 50% air/oxygen mixture and sevoflurane.The end-tidal concentration of sevoflurane was adjusted to maintain heart rate and blood pressure values within 20% of baseline. Mechanical ventilation was regulated to maintain the end-tidal carbon dioxide partial pressure ranging between

2018 Clinical Trials

105. Validation of the REPS Prediction Tool

Healthy Volunteers: Yes Sampling Method: Non-Probability Sample Study Population Adult patients who underwent non-cardiac surgery under general anesthesia with intermediate-acting NMBAs and are admitted to the Post-Anaesthesia Care Unit (PACU) after surgery. Criteria Inclusion Criteria: 18 years or older Non-cardiac surgery General anesthesia with intermediate-acting NMBAs (atracurium, cisatracurium, vecuronium, or rocuronium) PACU after surgery Exclusion Criteria: American Society of Anesthesiology

2018 Clinical Trials

106. The Effect of Pressure-controlled Ventilation-volume Guaranteed Mode

of Anesthesiologists physical status I-III who underwent lumbar spine surgery in prone position were enrolled. All patients fasted for 8 hours before the surgery and were premedicated with intramuscular glycopyrrolate 0.2 mg. Anesthesia was induced with remifentanil (0.1-0.2 ug/kg/min), propofol (1.5-2 mg/kg) and rocuronium (0.6 mg.kg) and maintained with sevoflurane (2.0-2.5 vol%) in inspired oxygen fraction with 0.5, remifentanil (0.05-0.3 ug/kg/min) and vecuronium (0.03-0.05 mg/kg/hr). A 20 G catheter

2018 Clinical Trials

107. Opioid-Free Shoulder Arthroplasty

: To identify and provide a safe, opioid-free treatment pathway for shoulder arthroplasty with a focus on perioperative pain control and postoperative symptoms from treatment Condition or disease Intervention/treatment Phase Opioid Use Shoulder Osteoarthritis Avascular Necrosis Rotator Cuff Tear Arthritis;Inflammatory Drug: Gabapentin Drug: Celecoxib Drug: toradol Drug: acetaminophen Drug: regional block Drug: propofol Drug: IV lidocaine Drug: rocuronium Drug: vecuronium Drug: sevoflurane Drug: desflurane (...) without the aid of opioid co-medication. Intra-op management by anesthesia with non-opioid modalities but should include one dose of IV acetaminophen during the procedure. Anesthetic modalities will include, but not limited to, regional block, propofol, IV lidocaine, rocuronium/vecuronium, and sevoflurane/desflurane. If the attending anesthesiologist deems it necessary to dose with opioids during procedure, it will be recorded and reported. Liposomal bupivacaine will be injected into the peri

2018 Clinical Trials

108. Midazolam Versus Dexamethasone-ondansetron in Preventing Postoperative Nausea-vomiting for Laparoscopic Surgeries

will be recruited for the study if they satisfy the inclusion and exclusion criteria as mentioned later. Consent will be obtained from the patients themselves. Standard protocol for administration of anaesthesia will be followed in all patients which is briefly described. All patients will receive general anaesthesia and will be induced with Propofol titrated to effect. Intraoperatively, isoflurane will be used as maintenance agent and vecuronium as non depolarizing muscle relaxant. For analgesia, patients

2018 Clinical Trials

109. Characterization of mouse neuro‐urological dynamics in a novel decerebrate arterially perfused mouse (DAPM) preparation Full Text available with Trip Pro

(>400 pM) caused dyssynergy of the LUT resulting in retention in DAPM as it increased tonic EUS activity and basal bladder pressure in a dose-dependent manner (basal pressure increase also noted in pithed DAPM). Both neuromuscular blockade (vecuronium) and autonomic ganglion blockade (hexamethonium), initially caused incomplete voiding, and both drugs eventually stopped voiding in DAPM. Intravesical acetic acid (0.2%) decreased the micturition interval. Recordings from the pelvic nerve in the pithed

2018 Neurourology and urodynamics

110. Use of Sugammadex in a Patient With Myotonic Dystrophy Full Text available with Trip Pro

Use of Sugammadex in a Patient With Myotonic Dystrophy One of the challenges during the perioperative care of patients with myotonic dystrophy is the reversal of neuromuscular blocking agents. Agents that inhibit acetylcholinesterase, such as neostigmine, may precipitate myotonia, and are therefore relatively contraindicated. Sugammadex is a novel pharmacologic agent, which encapsulates rocuronium or vecuronium, thereby reversing their effect. We report anecdotal experience with the use

2018 Cardiology Research

111. Estimation of the effect-site equilibration rate constant using the time-to-peak effect of muscle relaxants measured by train-of-four stimulation during general anesthesia induction Full Text available with Trip Pro

practice by applying a priming dose and train-of-four (TOF) during general anesthesia induction, and ke0 can be calculated from the tpe of the four muscle relaxants that are commonly used in general anesthesia.Eighty patients who received general anesthesia were divided into the succinylcholine, rocuronium, atracurium, or vecuronium groups. Priming doses of muscle relaxants were administered. The effects of muscle relaxants were quantified by recording the twitch response of the adductor pollicis (...) muscle after stimulating the ulnar nerve. The tpe was measured at the lowest TOF value. ke0 was calculated from the measured tpe .The ke0 values of the succinylcholine, rocuronium, atracurium, and vecuronium groups were 0.076 (0.030)/min, 0.228 (0.122)/min, 0.062 (0.011)/min, and 0.077 (0.019)/min, respectively.It is possible to estimate ke0 from the tpe of muscle relaxants using a priming dose and TOF during general anesthesia induction.

2018 Korean journal of anesthesiology

112. Guidelines on Smoking as Related to the Perioperative Period

) reactions as drug oxidation/hydroxylation. 21 Polycyclic aromatic hydrocarbons in smoke are principally involved in induction the isoenzymes CYP1A1, CYP1A2 and CYP2E1.21 Some anaesthetic drugs are also metabolised via these enzymes so this may explain some of the literature such as the increased requirements for vecuronium and rocuronium in smokers. 21 Smokers also have higher opioid requirements after surgery and experience more postoperative pain, although pharmacokinetic explanations via enzyme

2014 Australian and New Zealand College of Anaesthetists

113. Guidelines on Smoking as Related to the Perioperative Period Background Paper

Ethylene oxide 7mcg 1 Cigarette smoke induces liver enzymes in the cytochrome P450 system, which performs such (Phase 1) reactions as drug oxidation/hydroxylation. 75 Polycyclic aromatic hydrocarbons in smoke are principally involved in induction the isoenzymes CYP1A1, CYP1A2 and CYP2E1. 75 Some anaesthetic drugs are also metabolised via these enzymes so this in part may explain some of the literature such as the increased requirements for vecuronium and rocuronium in smokers. 75 Smokers also have

2014 Australian and New Zealand College of Anaesthetists

114. Guidelines on Smoking as Related to the Perioperative Period

) reactions as drug oxidation/hydroxylation. 21 Polycyclic aromatic hydrocarbons in smoke are principally involved in induction the isoenzymes CYP1A1, CYP1A2 and CYP2E1.21 Some anaesthetic drugs are also metabolised via these enzymes so this may explain some of the literature such as the increased requirements for vecuronium and rocuronium in smokers. 21 Smokers also have higher opioid requirements after surgery and experience more postoperative pain, although pharmacokinetic explanations via enzyme

2014 Australian and New Zealand College of Anaesthetists

118. Suxamethonium (succinylcholine) for RSI and intubation in head injury Full Text available with Trip Pro

) was administered to all subjects. Group 1a and 1b then received vecuronium (0.14mg/kg) and a second suxamethonium dose (1m/kg). Fisher’s exact test was used to determine significant increases in ICP. Poor quality cohort study; level IV Changes in parameters (cardiovascular, ICP) within individuals pre-and post-intervention. Peripheral radial arterial catheter and subarachnoid ICP bolt to gather data. Group 1: mean ICP rise from 15±1mmHg to 20±2mmHg after first suxamethonium dose (P Non-random group allocation (...) (vecuronium or metocurine). While this effect may be valid and of clinical importance, the use of these agents necessitated active ventilation in both study groups prior to suxamethonium administration - a measure which the principle of rapid sequence induction injured adult population may be inappropriate. It is worth noting that subjects in the Barrington paper (Barrington, Finer et al, 1989) were also manually ventilated, though in this case after suxamethonium administration. If the purpose

2012 BestBETS

119. Is rocuronium as effective as succinylcholine at facilitating laryngoscopy during rapid sequence intubation?

20 adult patients ASA 1-3, MAL 1-2 requiring RSI. Received 1.2mg/kg rocuronium or succinylcholine 1mg/kg. (30 other patients with lower doses of rocuronium or vecuronium also studied but not reviewed here) Double blind RCT (1) Time to onset muscle relaxant (nerve stimulator on adductor pollicis). (2) Intubating conditions at 60seconds (jaw relaxation, vocal cord postion and movement, diaphragm movement) (1) Time to onset; no significant difference (rocuronium = 55s (SD14 range 36-84) vs (...) in the emergency department Acad Emerg Med 2011 Jan;18(1):10-4 Andrews JI, Kumar N, van den Brom RH et al. A large simple randomized trial of rocuronium versus succinylcholine in rapid-sequence induction of anaesthesia along with propofol Acta Anaesthesiol Scand 1999 Jan;43(1):4-8. Magorian T, Flannery KB, Miller RD Comparison of rocuronium, succinylcholine, and vecuronium for rapid-sequence induction of anesthesia in adult patients Anesthesiology 1993 Nov;79(5):913-8 Perry JJ, Lee JS, Sillberg VA et al

2012 BestBETS

120. Comparison of the cardioprotective effects of dexmedetomidineand remifentanil in cardiac surgery Full Text available with Trip Pro

CABG surgery (n = 60) were included in this study. Anesthesia induction was introduced with propofol, fentanyl, and vecuronium bromide. Anesthesia was maintained with remifentanil infusion and sevoflurane in the remifentanil group (Group R) and with dexmedetomidine infusion and sevoflurane in the dexmedetomidine group (Group D). Blood samples for biochemical markers were taken from the coronary sinus catheter before cardiopulmonary bypass (T1), 20 min after aortic cross-clamping (T2), 20 min after

2017 Turkish Journal of Medical Sciences Controlled trial quality: uncertain

To help you find the content you need quickly, you can filter your results via the categories on the right-hand side >>>>