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81. Randomized Comparison of Isoflurane versus Sevoflurane and Desflurane for Maintenance of Ambulatory Anesthesia. Full Text available with Trip Pro

for elective ambulatory surgeries were divided into three groups. Suitable size laryngeal mask airway was inserted following induction with propofol and vecuronium. Anesthesia was maintained on low-flow anesthesia with inhalational agent as isoflurane for Group I, sevoflurane for Group II and Group III received desflurane. Patients were monitored for recovery as per modified Aldrete score and as per postanesthesia discharge scoring system for discharge from hospital. Cost analysis was done by Dion's

2019 Anesthesia, essays and researches Controlled trial quality: uncertain

82. Comparative Evaluation of Pregabalin and Clonidine as Preemptive Analgesics for the Attenuation of Postoperative Pain Following Thoracolumbar Spine Surgery. Full Text available with Trip Pro

. Alpha 2 agonists (e.g., clonidine) and gabapentenoids (e.g., pregabalin) are successfully used as part of a multimodal analgesic regimen.Total 75 patients were enrolled and randomly allocated into three groups. Group P received pregabalin (150 mg), group C received clonidine (150 mcg), and group N received placebo 90 minutes preoperatively. A standard anesthesia protocol comprising fentanyl, thiopentone, vecuronium, nitrous oxide, and oxygen in isoflurane was used for all patients. Postoperative

2019 Asian spine journal Controlled trial quality: uncertain

83. Early Enteral Nutrition in Patients Undergoing Sustained Neuromuscular Blockade: A Propensity-Matched Analysis Using a Nationwide Inpatient Database. (Abstract)

July 2010 to March 2016.More than 1,200 acute care hospitals covering approximately 90% of all tertiary-care emergency hospitals in Japan.Mechanically ventilated patients, who had undergone sustained treatment with neuromuscular blocking agents in an ICU, were retrospectively reviewed. We defined patients who received sustained treatment with neuromuscular blocking agents as those who received either rocuronium at greater than or equal to 250 mg/d or vecuronium at greater than or equal to 50 mg/d

2019 Critical Care Medicine

84. Immediate extubation after heart transplantation in a child by remifentanil-based ultra-fast anesthesia: A case report. Full Text available with Trip Pro

. Moist rales could be heard in the lung. Echocardiography revealed very large heart chambers, with an ejection fraction of 17%.The patient was diagnosed with dilated cardiomyopathy and scheduled to undergo an emergent operation for heart transplantation.The patient underwent an ultra-fast anesthesia protocol and ultra-fast reversal during heart transplantation. General anesthesia was induced with etomidate, fentanyl, and vecuronium; it was then maintained with remifentanil-based total intravenous

2019 Medicine

85. Efficacy of bupivacaine infiltration in preventing haemodynamic changes during craniotomy. (Abstract)

with morphine and promethazine and were anaestetised using conventional general anaesthesia technique including 02, N20 vecuronium and morphine. Ventilation was controlled so as to maintain PaCO2 between 25-30 mm Hg. EKG, heart rate and direct arterial pressure were monitored at various events during craniotomy. In control group there was a statistically significant increase in systolic arterial pressure and heart rate after scalp infiltration, scalp incision, during scalp flap reflection, burr hole

2019 Neurology India Controlled trial quality: uncertain

86. Assessing cross-reactivity to neuromuscular blocking agents by skin and basophil activation tests in patients with neuromuscular blocking agent anaphylaxis. (Abstract)

, there is significant risk. In vitro, after an allergen activates basophils, basophils express surface activation markers that can be measured by basophil activation testing (BAT). We compared cross-reactivity between NMBAs assessed by BAT against that by skin testing.All patients attending an anaesthetic allergy clinic in Sydney, Australia between May 2017 and July 2018 diagnosed with NMBA anaphylaxis qualified for this study comparing intradermal skin tests and BAT with a panel of NMBAs (rocuronium, vecuronium (...) , pancuronium, suxamethonium, cisatracurium).Of the 61 patients participating, sensitisation on skin testing and on BAT completely matched in only nine patients (15%). Sensitisation was not in agreement for pancuronium, cisatracurium and rocuronium, but was in agreement for vecuronium and suxamethonium. Nine patients with negative skin tests subsequently tolerated cisatracurium, and one false positive on BAT to cisatracurium was detected.The utility of BAT in identifying safe NMBAs for subsequent

2019 British Journal of Anaesthesia

87. Anesthesia Among Patients Undergoing Knee Arthroplasty

arthroplasty Knee group: 20 (10/10) Continuous epidural (bupivacaine plus morphine) for 48 hours post-surgery and oral piroxacam General anesthesia and intramuscular opioid (midazolam, fentanyl, and pancuronium) and acetaminophen Williams- Russo et al, 1995 (7) Knee arthroplasty 262 (134/128) Epidural (lidocaine or bupivicaine, and midazolam or fentanyl) and post-surgery epidural analgesia as requested General anesthesia (thiopental sodium, fentanyl, vecuronium, and nitrous oxide) and post-surgery (...) intravenous analgesia Williams- Russo et al, 1996 a (8) Knee arthroplasty 178 (97/81) Epidural (lidocaine or bupivicaine, and midazolam or fentanyl) and post-surgery epidural analgesia as requested General anesthesia (thiopental sodium, fentanyl, vecuronium, and nitrous oxide) and post-surgery intravenous analgesia a Subgroup of Williams-Russo et al, 1995 study (7) of patients who received thromboembolic prophylaxis. Anesthesia Among Patients Undergoing Knee Arthroplasty: A Rapid Review. November 2013; pp

2013 Health Quality Ontario

88. Effects of neostigmine or edrophonium on force of contraction when administered at a train-of-four ratio of 0.9 in anesthetized dogs. (Abstract)

study.A total of 12 Beagle dogs.Each dog was anesthetized twice with propofol and maintained with isoflurane and dexmedetomidine. Intravenous (IV) vecuronium (0.1 mg kg-1) was administered. When the mechanographic train-of-four (TOF) ratio had spontaneously recovered to ≥0.9, either neostigmine (0.04 mg kg-1) or edrophonium (0.5 mg kg-1) was administered IV, preceeded by atropine. Changes in twitch height or TOF ratio were measured for the next 10 minutes. Recurarization was considered to be present

2018 Veterinary anaesthesia and analgesia Controlled trial quality: uncertain

89. [Effect of perioperative multi-day low dose ketamine infusion on prevention of postmastectomy pain syndrome]. (Abstract)

) and ketamine group (group K). Patients in group K were infused with 0.5 mg/kg of ketamine mixed in 250 ml of 0.9% normal saline in 1 h daily for 7 days. Patients in group C were infused the same dose of 0.9% normal saline. Anesthesia induction in both groups were given intravenous midazolam, sufentanil, propofol, vecuronium and intermittent positive pressure ventilation after tracheal intubation, anesthesia was maintained with propofol and remifentanil. After awakening, all patients were monitored

2018 Zhonghua yi xue za zhi Controlled trial quality: uncertain

90. Hemodynamic responses and plasma phenylephrine concentrations associated with intranasal phenylephrine in children. (Abstract)

% phenylephrine in children.After Institutional Review Board and parental approval, 77 children between the ages of 2 and 12 years were studied in a prospective, double-blind manner and randomized into three groups. Group 1 received intranasal saline, while groups 2 and 3 received 0.1 mL/kg of 0.25% or 0.5% phenylephrine, respectively. All received the same anesthetic of halothane, N2 O, O2 , and vecuronium. After inhalation induction, endtidal halothane and PaCO2 were maintained at 1.5% and 35 mm Hg

2018 Paediatric anaesthesia Controlled trial quality: uncertain

91. Reversal of Deep Pipecuronium-Induced Neuromuscular Block With Moderate Versus Standard Dose of Sugammadex: A Randomized, Double-Blind, Noninferiority Trial. (Abstract)

Reversal of Deep Pipecuronium-Induced Neuromuscular Block With Moderate Versus Standard Dose of Sugammadex: A Randomized, Double-Blind, Noninferiority Trial. Certain surgical interventions may require a deep neuromuscular block (NMB). Reversal of such a block before tracheal extubation is challenging. Because anticholinesterases are ineffective in deep block, sugammadex 4 mg/kg has been recommended for the reversal of rocuronium- or vecuronium-induced deep NMB. However, this recommendation

2018 Anesthesia and Analgesia

92. Effects of Hypotensive Anesthesia on Thiol Disulphide Balance

Faculty Training and Research Hospital. Participants with uncontrolled hypertension, diabetes mellitus, cerebrovascular disease, cogulopathy, morbid obesity (BMI ≥35) and renal disease will not be taken. Participants were first pre-medicated with an infusion of midazolam 0.05 mg/kg, fentanyl 1 µg/kg, lidocaine 1 mg/kg. Induction of anesthesia was achieved with an infusion of propofol 1-2 mg/kg and vecuronium bromide 0.6 mg/kg and after 2 to 3 minutes participants were intubated with the appropriate

2018 Clinical Trials

93. the Efficacy and Safety of Sugammadex in Children 0-2 Years Old

Research Institute of Pediatric Hematology, Oncology and Immunology Information provided by (Responsible Party): Federal Research Institute of Pediatric Hematology, Oncology and Immunology Study Details Study Description Go to Brief Summary: Sugammadex is a selective antidote to muscle relaxants rocuronium bromide and vecuronium bromide. Sugammadex is a modified gamma-cyclodextrin, a compound that selectively binds rocuronium bromide and vecuronium bromide. It forms a complex with them in the blood (...) plasma, which leads to the decrease in the concentration of muscle relaxant binding to nicotinic receptors in the neuromuscular synapse. The result is the the elimination of neuromuscular blockade caused by rocuronium bromide or vecuronium bromide. Sugammadex is used to eliminate neuromuscular blockade caused by rocuronium bromide in children aged 2 years and adolescents in standard clinical situations. The aim of the study is to prove the efficacy and safety of sugammadex in children under 2 years

2018 Clinical Trials

94. Retrospective Evaluation of Patients who Underwent Laparoscopic Bariatric Surgery Full Text available with Trip Pro

in anaesthesia and analgesia, the duration of recovery unit/hospital stay, intensive care unit/mechanical ventilation requirements and complications were recorded.A total of 329 ASA II-III patients over a 3-year period were operated. Thiopental and propofol were administered at induction, sevoflurane, isoflurane and desflurane were administered for the maintenance, and vecuronium and rocuronium were administered to aid in neuromuscular blockage. The mean durations of recovery unit and hospital stays were

2018 Turkish journal of anaesthesiology and reanimation

95. Perioperative management of patients with pre-excitation syndromes Full Text available with Trip Pro

safely. Among neuromuscular blockers, cis-atracurium, rocuronium and vecuronium are good choices. Ketamine, pancuronium and pethidine should be avoided because of their sympathomimetic actions. Anticholinergic/ anticholinesterase combinations for neuromuscular block reversal should preferably be omitted, while sugammadex seems more attractive. In regional anaesthesia, addition of epinephrine and high sympathetic blocks should be avoided. Hypotension should be treated with pure alpha-adrenergic

2018 Romanian Journal of Anaesthesia and Intensive Care

96. Rapid Sequence Intubation in Traumatic Brain-injured Adults Full Text available with Trip Pro

Rapid Sequence Intubation in Traumatic Brain-injured Adults Deciding on proper medication administration for the traumatic brain injury (TBI) patient undergoing intubation can be daunting and confusing. Pretreatment with lidocaine and/or vecuronium is no longer recommended; however, high-dose fentanyl can be utilized to help blunt the sympathetic stimulation of intubation. Induction with etomidate is recommended; however, ketamine can be considered in the proper patient population

2018 Cureus

97. Management of Refractory Orofacial Dyskinesia Caused by Anti-N-methyl-d-aspartate Receptor Encephalitis Using Botulinum Toxin Full Text available with Trip Pro

in the masseter, and induced muscle paralysis using vecuronium. The patient's severe orofacial dyskinesia was controlled. We observed the effects of the BoNT-A injections and a tapering off of the effects of vecuronium 10 days after the treatment. The movement disorder had improved significantly 4 weeks after the first administration of rituximab. The injection of BoNT-A into the masseter may be an effective treatment for medically refractory orofacial dyskinesia in pediatric patients with anti-NMDAR

2018 Frontiers in neurology

98. Effects of Premedication on Heart Rate Variability at Induction of Anaesthesia: Comparison between Midazolam and Hydroxyzine Full Text available with Trip Pro

was facilitated with vecuronium 0.15 mg kg-1. Blood pressure, heart rate and HRV were measured at predetermined time points for 10 min after intubation.Systolic blood pressure and heart rate significantly increased after intubation in both groups and the increase was greater in the hydroxyzine group. The high frequency (HF) component decreased significantly in both groups, and no difference was found between the two groups. The low frequency component/HF ratio significantly increased in the hydroxyzine group

2018 Turkish journal of anaesthesiology and reanimation Controlled trial quality: uncertain

100. Practice Change From Intermittent Medication Boluses to Bolusing From a Continuous Infusion in Pediatric Critical Care: A Quality Improvement Project. (Abstract)

hospital.Patients less than 18 years old admitted to the PICU or pediatric cardiac ICU receiving a continuous infusion of dexmedetomidine, midazolam, fentanyl, morphine, vecuronium, or cisatracurium from May 2015 to May 2016, excluding November 2015 (washout period), were eligible for inclusion.Change in practice from administering bolus doses from an automated dispensing machine to administering bolus medications from continuous infusion in PICUs.Timing studies were conducted pre- and post implementation in 29

2018 Pediatric Critical Care Medicine

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