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Vecuronium

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61. Perioperative management of people with inherited salt-wasting alkaloses (Gitelman?s syndrome and Bartter?s syndrome) undergoing non-urgent surgical procedure

with Bartter’s/Gitelman’s syndromes. Clin Nephrol. 2007 Mar;67(3):193–7. 4. Abston PA, Priano LL. Bartter’s syndrome: anesthetic implications based on pathophysiology and treatment. Anesth Analg. 1981 Oct;60(10):764–6. 5. Nishikawa T, Dohi S. Baroreflex function in a patient with Bartter’s syndrome. Can Anaesth Soc J. 1985 Nov;32(6):646–50. 6. Chenoweth D. Successful use of isoflurane and vecuronium in a patient with Bartter’s syndrome: a case study. AANA J. 1987 Nov;55(5):434–6. 7. Higa K, Ishino H, Sato S

2015 Renal Association

63. Guideline for the perioperative management of people with inherited salt-wasting alkaloses (Gitelman?s syndrome and Bartter?s syndrome) undergoing non-urgent surgical procedures

with Bartter’s/Gitelman’s syndromes. Clin Nephrol. 2007 Mar;67(3):193–7. 4. Abston PA, Priano LL. Bartter’s syndrome: anesthetic implications based on pathophysiology and treatment. Anesth Analg. 1981 Oct;60(10):764–6. 5. Nishikawa T, Dohi S. Baroreflex function in a patient with Bartter’s syndrome. Can Anaesth Soc J. 1985 Nov;32(6):646–50. 6. Chenoweth D. Successful use of isoflurane and vecuronium in a patient with Bartter’s syndrome: a case study. AANA J. 1987 Nov;55(5):434–6. 7. Higa K, Ishino H, Sato S

2015 Royal College of Anaesthetists

65. Immediate extubation after heart transplantation in a child by remifentanil-based ultra-fast anesthesia: A case report. (PubMed)

. Moist rales could be heard in the lung. Echocardiography revealed very large heart chambers, with an ejection fraction of 17%.The patient was diagnosed with dilated cardiomyopathy and scheduled to undergo an emergent operation for heart transplantation.The patient underwent an ultra-fast anesthesia protocol and ultra-fast reversal during heart transplantation. General anesthesia was induced with etomidate, fentanyl, and vecuronium; it was then maintained with remifentanil-based total intravenous

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2019 Medicine

66. Assessing cross-reactivity to neuromuscular blocking agents by skin and basophil activation tests in patients with neuromuscular blocking agent anaphylaxis. (PubMed)

, there is significant risk. In vitro, after an allergen activates basophils, basophils express surface activation markers that can be measured by basophil activation testing (BAT). We compared cross-reactivity between NMBAs assessed by BAT against that by skin testing.All patients attending an anaesthetic allergy clinic in Sydney, Australia between May 2017 and July 2018 diagnosed with NMBA anaphylaxis qualified for this study comparing intradermal skin tests and BAT with a panel of NMBAs (rocuronium, vecuronium (...) , pancuronium, suxamethonium, cisatracurium).Of the 61 patients participating, sensitisation on skin testing and on BAT completely matched in only nine patients (15%). Sensitisation was not in agreement for pancuronium, cisatracurium and rocuronium, but was in agreement for vecuronium and suxamethonium. Nine patients with negative skin tests subsequently tolerated cisatracurium, and one false positive on BAT to cisatracurium was detected.The utility of BAT in identifying safe NMBAs for subsequent

2019 British Journal of Anaesthesia

67. Factors associated with post-intubation sedation after emergency department intubation: A Report from The National Emergency Airway Registry. (PubMed)

with a higher odd of post-intubation sedation compared to a long-acting neuromuscular blocking agent (i.e. rocuronium or vecuronium) (1.89; 1.68-2.12).Post-intubation sedation rates in NEAR are higher than previously reported and multiple factors including the indication for intubation and succinylcholine use, are associated with higher odds of receiving post-intubation sedation.Copyright © 2019 Elsevier Inc. All rights reserved.

2019 American Journal of Emergency Medicine

68. Resistance towards nondepolarising muscle relaxants: prolonged onset time: A systematic review. (PubMed)

of patient groups with resistance towards NDMRs. A prolonged onset time was defined as a difference that exceeded 25% compared with controls.A systematic review of randomised controlled trials and cohort studies.A comprehensive search was performed in 2016 in PubMed and EMBASE.Patients with conditions or diseases, or patients taking medication, which lead to resistance towards current NDMRs (rocuronium, vecuronium, cisatracurium, atracurium, mivacurium and pancuronium). Included outcomes were onset time

2019 European Journal of Anaesthesiology

69. Retrospective Analysis of the Safety and Efficacy of Sugammadex Versus Neostigmine for the Reversal of Neuromuscular Blockade in Children. (PubMed)

Retrospective Analysis of the Safety and Efficacy of Sugammadex Versus Neostigmine for the Reversal of Neuromuscular Blockade in Children. Sugammadex, with its novel mechanism of action of encapsulation and noncompetitive binding of aminosteroid neuromuscular-blocking agents (rocuronium and vecuronium), may offer distinct advantage to pediatric patients where residual neuromuscular blockade may be poorly tolerated. Data describing its use in the pediatric population are limited, and no large

2019 Anesthesia and Analgesia

70. The effect of magnesium sulfate on surgical field during endoscopic sinus surgery: A meta-analysis of randomized controlled trials. (PubMed)

 = -89.09; 95% CI = -163.20 to -14.97; P = .02), but shows no markedly effect on surgery duration (MD = -7.08; 95% CI = -21.38 to 7.22; P = .33), fentanyl (MD = -0.64; 95% CI = -1.97 to 0.70; P = .35), and vecuronium (MD = -3.64; 95% CI = -10.99 to 3.70; P = .33).Magnesium sulfate exerts positive impact on surgical field and blood loss reduction for endoscopic sinus surgery.

2019 Medicine

71. Early Enteral Nutrition in Patients Undergoing Sustained Neuromuscular Blockade: A Propensity-Matched Analysis Using a Nationwide Inpatient Database. (PubMed)

July 2010 to March 2016.More than 1,200 acute care hospitals covering approximately 90% of all tertiary-care emergency hospitals in Japan.Mechanically ventilated patients, who had undergone sustained treatment with neuromuscular blocking agents in an ICU, were retrospectively reviewed. We defined patients who received sustained treatment with neuromuscular blocking agents as those who received either rocuronium at greater than or equal to 250 mg/d or vecuronium at greater than or equal to 50 mg/d

2019 Critical Care Medicine

72. The effect of volatile anaesthetics on the relative sensitivity of facial and distal thoracic limb muscles to vecuronium in dogs. (PubMed)

The effect of volatile anaesthetics on the relative sensitivity of facial and distal thoracic limb muscles to vecuronium in dogs. To compare n. facialis-m. nasolabialis (nF-mNL) and n. ulnar-mm. carpi flexorii (nU-mCF) sensitivity to vecuronium during halothane or isoflurane anaesthesia.Randomized, prospective, experimental study.Forty-four client-owned dogs (19 male, 25 female) undergoing surgery; mean age: 5.0 years; mean body mass: 24.7 kg.Thirty minutes after acepromazine (0.05 mg kg(-1 (...) )) and morphine (0.5 mg kg(-1)), anaesthesia was induced with intravenous (IV) thiopental and maintained with either halothane (n = 22) or isoflurane (randomly allocated) in oxygen. The lungs were mechanically ventilated and end-tidal inhaled anaesthetic (FE'(IAA)) maintained at 1.2 x MAC values. Neuromuscular transmission at nF-uNL and nU-mCF was monitored using the train of four count. Vecuronium (50 microg kg(-1) IV) was injected (t = 0) after 15 trains, 50-60 minutes after inhalational anaesthesia began

2009 Veterinary anaesthesia and analgesia

73. Priming with rocuronium or vecuronium prevents remifentanil-mediated muscle rigidity and difficult ventilation. (PubMed)

Priming with rocuronium or vecuronium prevents remifentanil-mediated muscle rigidity and difficult ventilation. The aim of this study was to test our hypothesis that priming with rocuronium would prevent muscle rigidity and difficult ventilation due to remifentanil administration.One hundred patients, American Society of Anesthesiologists (ASA) status I or II, were recruited into the study, and randomly allocated to one of four protocols (n = 25 each). Remifentanil was administered at 0.2 (...) microg.kg(-1).min(-1) in group A and at 0.7 microg.kg(-1).min(-1) in groups B, C, and D. Priming with vecuronium (0.02 mg.kg(-1)) or rocuronium (0.06 mg.kg(-1)) was performed at the same time as the infusion of remifentanil in groups C and D, respectively. Anesthesia was induced with 1 mg.kg(-1)propofol 2 min after the start of remifentanil infusion. After the patient had lost consciousness, the anesthesiologist performed mask ventilation, and watched for the presence of muscle rigidity. Ventilation

2009 Journal of anesthesia

74. The post-tetanic count during vecuronium-induced neuromuscular blockade in halothane-anaesthetized dogs. (PubMed)

The post-tetanic count during vecuronium-induced neuromuscular blockade in halothane-anaesthetized dogs. To evaluate the post-tetanic count (PTC) for predicting the return of reversible neuromuscular blockade at the n. facialis-m. nasolabialis (nF-mNL) and n. ulnaris-mm. carpi flexorii (nU-mCF) nerve-muscle units (NMUs) during profound vecuronium neuromuscular blockade in halothane-anaesthetized dogs.Randomized, prospective, experimental study.Twenty-five dogs (seven male 18 female) undergoing (...) surgery; mean age: 4.8 years; mean body weight 22 kg.Thirty minutes after acepromazine (0.05 mg kg(-1)) and morphine (0.5 mg kg(-1)) pre-medication, anaesthesia was induced with intravenous (IV) thiopental and maintained with halothane, N(2)O and O(2). The lungs were mechanically ventilated and end-tidal halothane concentration (Fe'(HAL)) maintained at 1.04%. Neuromuscular transmission was monitored using the train-of-four count (TOFC) at one nF-mNL and both nU-mCF units. Vecuronium (50 microg kg(-1

2009 Veterinary anaesthesia and analgesia

75. [Effects of changes in ion concentrations, osmolarity, and pH on recovery from atracurium- or vecuronium-induced neuromuscular blockade]. (PubMed)

[Effects of changes in ion concentrations, osmolarity, and pH on recovery from atracurium- or vecuronium-induced neuromuscular blockade]. To determine changes in sodium, potassium, calcium, magnesium and chloride ion concentrations in blood, osmolarity, and pH during surgery, and to assess the influence of such changes on atracurium- or vecuronium-induced neuromuscular blockade under inhaled or intravenous anesthesia.Prospective study randomizing 119 ASA 1-2 patients; 52.1% of the patients (...) received atracurium (26.8%, with isoflurane; 25.2%, with propofol) and 47.9% received vecuronium (23.5%, with isoflurane; 24.3%, with propofol). The neuromuscular blockade was confirmed by electromyography of the adductor pollicis muscle (stimuli delivered to the cubital nerve). Two venous blood samples were extracted to measure ureic nitrogen, creatinine, glucose, ion concentrations (sodium, chloride, potassium, calcium, and magnesium), and osmolarity. Arterial blood gases and pH were also assessed

2009 Revista española de anestesiología y reanimación

76. Comparative Study of Rocuronium With Vecuronium (Study 71101)(COMPLETED)

Comparative Study of Rocuronium With Vecuronium (Study 71101)(COMPLETED) Comparative Study of Rocuronium With Vecuronium (Study 71101)(COMPLETED) - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Comparative (...) Study of Rocuronium With Vecuronium (Study 71101)(COMPLETED) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT00970762 Recruitment Status : Completed First Posted : September 2, 2009 Last Update Posted : April 17, 2015 Sponsor: Merck Sharp & Dohme Corp. Information provided by (Responsible Party

2009 Clinical Trials

77. Investigation of the relaxant effects of pancuronium, rocuronium, vecuronium and mivacurium on rat thoracic aorta. (PubMed)

Investigation of the relaxant effects of pancuronium, rocuronium, vecuronium and mivacurium on rat thoracic aorta. Pancuronium, vecuronium, mivacurium and rocuronium are nondepolarizing neuromuscular blocking agents, which are competitive antagonists against acetylcholine at nicotinic receptors, and considered to have no direct actions on vascular smooth muscle. We aimed to investigate the relaxant effects and possible underlying mechanisms of these agents on isolated rat thoracic aorta.The (...) preparations were precontracted with prostaglandin F2alpha (10(-7) mol l(-1)) and pancuronium (10(-7)-10(-4) mol l(-1)), rocuronium (10(-7)-10(-4) mol l(-1)), vecuronium (10(-7)-10(-4) mol l(-1)) and mivacurium (10(-7)-10(-4) mol l(-1)) added at cumulative concentrations in the presence or absence of a prostaglandin synthesis inhibitor, indomethacin (10(-6) M), and a nitric oxide synthesis inhibitor, N(omega)-nitro-L-arginine methylester (3 x 10(-5)). The same protocol was applied to both endothelia

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2009 European Journal of Anaesthesiology

78. What, besides large anterior STEMI, is so ominous about this ECG?

is the ominous finding: Right Bundle Branch Block (RBBB) + LAFB (left anterior fascicular block) . I have seen a dozen cases of STEMI with RBBB and LAFB . All were close to death. : See these cases: Treatments : 1. Aspirin 325 mg 2. Ticagrelor 180 mg 3. Atorvastatin 80 mg (small studies support this) 4. Heparin bolus 5. Fluid challenge 6. Because cardiogenic shock is likely to get worse, even after reperfusion (because myocardial stunning lasts many days), we intubated the patient. 7. Vecuronium paralysis 8

2016 Dr Smith's ECG Blog

79. Task Force 5: Pediatric Cardiology Fellowship Training in Critical Care Cardiology

inhibitors, calcium channel antagonists, beta-adrenergic antagonists, nitric oxide donors) • Commonly used antiarrhythmic agents (eg, digoxin, adenosine, esmolol/propranolol, procainamide, lido- caine, amiodarone) • Pulmonary vasodilators (eg, inhaled nitric oxide, prosta- cyclin, PDE5 inhibitors) • Prostaglandin E 1 • Neuromuscular blocking agents (eg, pancuronium, vecuronium, rocuronium, succinylcholine) • Analgesics and sedatives (eg, opiates, ketamine, benzo- diazepines, dexmedetomidine

2015 American Heart Association

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