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Vecuronium

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181. The Effect of TEAS on the Quality of Early Recovery

) on the quality of early recovery in the patients undergoing gynecological laparoscopic surgery. Condition or disease Intervention/treatment Phase C.Delivery; Surgery (Previous), Gynecological Inappropriate Device Stimulation of Tissue Delayed Emergence From Anesthesia Other: TEAS Other: Con Drug: propofol, remifentanil, vecuronium Other: mechanical ventilation Not Applicable Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Actual Enrollment : 60 participants (...) by the National Library of Medicine available for: Arms and Interventions Go to Arm Intervention/treatment TEAS Group TEAS consisted of 30 min of stimulation (12-15 mA, 2/100 Hz) at the Hegu (L14) and Neiguan (PC6) before anesthesia. Anesthesia was induced i.v. with propofol (2 mg kg-1) and remifentanil (1 μg kg-1) using a target-controlled infusion (TCI) system. After loss of consciousness, vecuronium (0.1 mg kg-1) was administered i.v. Patients' lungs were mechanically ventilated in a volume-controlled mode

2015 Clinical Trials

182. To study the effect of injection dexmedetomidine for prevention of pain due to propofol injection and to compare it with injection lignocaine. (PubMed)

and isoflurane on intermittent positive pressure ventilation with Bain's circuit and inj. vecuronium was used as muscle relaxant.Demographic data showed that there was no statistically significant difference between the 2 groups. There was no statistically significant difference between 2 groups in respect to inj. propofol pain. No adverse effects like oedema, pain, wheal response at the site of injection were observed in the two groups.Copyright © 2013 Sociedade Brasileira de Anestesiologia. Published

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2015 Brazilian journal of anesthesiology (Elsevier)

183. Effects of stellate ganglionic block on hemodynamic changes and intrapulmonary shunt in perioperative patients with esophageal cancer. (PubMed)

. Endobronchial occluder was placed blindly after tracheal indubation and the correct position was verified by auscultation and fiberoptic bronchoscopy. The patients were mechanically ventilated. The ventilation conditions were Fio2=100%, VT = 8-10 ml/kg, I: E = 1:2 and respiratory rate was adjusted to maintained PETCO2 at 35-45 mmHg during both two-lung ventilation (TLV) and OLV. Anesthesia was maintained with continuous infusion of propofol 4-10 mg/kg·h, sufentanil 0.2 μg/kg·h, vecuronium o.1 mg/kg·h, BIS

2015 European review for medical and pharmacological sciences

184. Effect of gabapentin pretreatment on the hemodynamic response to laryngoscopy and tracheal intubation in treated hypertensive patients. (PubMed)

with endotracheal intubation, were randomly allocated into three groups. Group 1 patients received placebo at night and 2 hours prior to induction of anesthesia. Group 2 patients received placebo at night and 800 mg gabapentin 2 hours prior to induction of anesthesia. Group 3 patients received 800 mg gabapentin at night and 2 hours prior to induction of anesthesia. Anesthesia was induced with thiopentone, fentanyl, and vecuronium and maintained with isoflurane in oxygen and nitrous oxide. Patients' heart rate

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2015 Acta anaesthesiologica Taiwanica : official journal of the Taiwan Society of Anesthesiologists

185. [To study the effect of injection dexmedetomidine for prevention of pain due to propofol injection and to compare it with injection lignocaine]. (PubMed)

and isoflurane on intermittent positive pressure ventilation with Bain's circuit and inj. vecuronium was used as muscle relaxant.Demographic data showed that there was no statistically significant difference between the 2 groups. There was no statistically significant difference between 2 groups in respect to inj. propofol pain. No adverse effects like oedema, pain, wheal response at the site of injection were observed in the two groups.Copyright © 2013 Sociedade Brasileira de Anestesiologia. Publicado por

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2015 Revista brasileira de anestesiologia

186. Comparison of hemodynamic effects of intravenous etomidate versus propofol during induction and intubation using entropy guided hypnosis levels. (PubMed)

intravenous midazolam 0.03 mg kg(-1) and fentanyl 2 μg kg(-1) as premedication. After induction with the desired agent titrated to entropy 40, vecuronium 0.1 mg kg(-1) was administered for neuromuscular blockade. Heart rate, systolic, diastolic and mean arterial pressures, response entropy [RE] and state entropy [SE] were recorded at baseline, induction and upto three minutes post intubation. Data was subject to statistical analysis SPSS (version 12.0) the paired and the unpaired Student's T-tests

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2015 Journal of anaesthesiology, clinical pharmacology

187. [Effect of intraoperative esmolol infusion on anesthetic, analgesic requirements and postoperative nausea-vomitting in a group of laparoscopic cholecystectomy patients]. (PubMed)

, postoperative pain and PNV.Sixty patients have been included. Propofol, remifentanil and vecuronium were used for induction. Study groups were as follows; I - Esmolol infusion was added to maintenance anesthetics (propofol and remifentanil), II - Only propofol and remifentanil was used during maintenance, III - Esmolol infusion was added to maintenance anesthetics (desflurane and remifentanil), IV - Only desflurane and remifentanil was used during maintenance. They have been followed up for 24h for PNV

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2015 Revista brasileira de anestesiologia

188. Comparison of train-of-four count by anesthesia providers versus TOF-Watch<sup>®</sup> SX: a prospective cohort study. (PubMed)

of Anesthesiologists physical status III or less and undergoing elective surgery. During recovery from an intubating dose of rocuronium or vecuronium, the TOF count was measured every 15 sec using TOF-Watch SX. Anesthesia providers assessed the TOF count twice at each level of TOF-count, 15 sec after the TOF-Watch SX count increased to the next level and then two to five minutes later.In 75 patients, 687 observations were collected. There was agreement between the TOF-Watch SX and the subjective assessment

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2015 Canadian Journal Of Anaesthesia

189. Sedation after airway reconstruction in children: A protocol to reduce withdrawal and length of stay. (PubMed)

. eng Journal Article 2015 07 07 United States Laryngoscope 8607378 0023-852X 0 Analgesics, Opioid 0 Hypnotics and Sedatives 0 Neuromuscular Nondepolarizing Agents 76I7G6D29C Morphine 7E4PHP5N1D Vecuronium Bromide O26FZP769L Lorazepam IM Analgesics, Opioid administration & dosage Child, Preschool Conscious Sedation methods Drug Therapy, Combination Female Follow-Up Studies Humans Hypnotics and Sedatives administration & dosage Infant Infusions, Intravenous Laryngoplasty Laryngostenosis surgery (...) Length of Stay trends Lorazepam administration & dosage Male Morphine administration & dosage Neuromuscular Nondepolarizing Agents administration & dosage Pain, Postoperative therapy Postoperative Care methods Retrospective Studies Tracheal Stenosis surgery Treatment Outcome Vecuronium Bromide administration & dosage Laryngotracheal reconstruction clinical pathway mandibular distraction osteogenesis pediatric airway reconstruction pediatric sedation 2014 11 19 2015 01 05 2015 7 9 6 0 2015 7 15 6 0

2015 Laryngoscope

190. Assessment of Cognitive Functions and Quality of Life in Patients Undergoing Surgery for Supratentorial Brain Tumor

of Medicine related topics: available for: Arms and Interventions Go to Arm Intervention/treatment Experimental: intravenous anesthesia propofol infusion @ 100-200 mcg/kg/min for maintenance of anesthesia Drug: Propofol Propofol infusion @100-200 mcg/kg/min Fentanyl 1mcg/kg Vecuronium 0.1mg/kg Mannitol 1 gm/kg Other Name: 2,6-di(propan-2-yl)phenol Active Comparator: inhalational anesthesia sevoflurane MAC between 0.8-1.2 for maintenance of anesthesia Drug: Sevoflurane MAC of Sevoflurane will be maintained (...) between 0.8-1.2 Fentanyl 1mcg/kg Vecuronium 0.1mg/kg Mannitol 1 gm/kg Other Name: fluoromethyl hexafluoroisopropyl ether Outcome Measures Go to Primary Outcome Measures : Cognitive functions [ Time Frame: Six month. ] Secondary Outcome Measures : Adverse events [ Time Frame: 24 hours ] Number of patients suffering delay in emergence, hemodynamic instability, nausea, vomiting, pneumocephalus. Eligibility Criteria Go to Information from the National Library of Medicine Choosing to participate in a study

2015 Clinical Trials

191. The Safety and Efficacy of the Enhanced Recovery After Surgery(ERAS)Applied on Cardiac Surgery With Cardiopulmonary Bypass

during the surgery Procedure: ERAS group Protective ventilation strategy:Low tidal volume about 6~8ml/kg and positive end expiratory pressure(PEEP) combined with lung recruitment maneuver Other Name: Lung protection measure during the surgery(Dräger Primus) Procedure: ERAS group Bilateral thoracic paravertebral block before induction of anesthesia; Fast channel anesthesia: Induction use Sufentanil 0.5~1ug/kg, Vecuronium for Injection 0.15mg/kg and Etomidate 0.2~0.6mg/kg; ②. Maintain use Remifentanil (...) Hydrochloride for Injection 0.1~0.4ug/kg·min, Propofol Injection 2~6mg/kg·h, Sevoflurane 0.5~1.5(minimum alveolar concentration) and Infusing Dexmedetomidine which load dose 0.5μg/kg in 10min then changed into 0.5-1.0μg/kg·h,Vecuronium 0.06~0.12mg/kg·h; ③. Intravenous hydromorphone Hydrochloride Injection 0.15mg/kg before surgery over. Other Name: Anesthesia drugs during the surgery Procedure: ERAS group Drink water after 6h, 200ml once, 2~3 times / day, early ambulation,mobilization within 48 h

2015 Clinical Trials

192. Evaluation of Periop Biochemical Stress Factors in Craniotomy Neurosurgical Procedure With Respect to Preop Hypertension

(and the patient's radial artery (non-dominant arm) will be cannulated for further blood sampling and blood pressure monitoring (Agilent Technologies, MA, USA). Anaesthesia will beinduced with thiopental (4-5 mg.kg-1) and fentanyl, (1-2μg.kg-1). Vecuronium, (0.06-0.1 mgkg-1) will be administered to facilitate tracheal intubation and to maintain neuromuscular blockade. Isoflurane (0.7 - 1.2 MAC) will be administered to maintain the Bispectral Index (BIS) (Aspect Medical System Inc, MA, USA), within the range (...) of 35 - 45. End tidal CO2 partial pressure will be maintained between 4-4.6 kPa (IntelliVue Anesthetic Gas Modules-G1, Redmond, WA, USA). During the surgery, intravenous fentanyl and vecuronium will be administered at the discretion of the anaesthetist for pain control and muscle relaxation respectively. An increase in mean arterial pressure (MAP) in excess of 20% of the pre-operative value will be treated either by increasing the inspired isoflurane concentration or by administering metoprolol

2015 Clinical Trials

193. Comparative Effectiveness of Calabadion and Sugammadex to Reverse Non-depolarizing Neuromuscular-blocking Agents. (PubMed)

Comparative Effectiveness of Calabadion and Sugammadex to Reverse Non-depolarizing Neuromuscular-blocking Agents. The authors evaluated the comparative effectiveness of calabadion 2 to reverse non-depolarizing neuromuscular-blocking agents (NMBAs) by binding and inactivation.The dose-response relationship of drugs to reverse vecuronium-, rocuronium-, and cisatracurium-induced neuromuscular block (NMB) was evaluated in vitro (competition binding assays and urine analysis), ex vivo (n = 34 (...) times the affinity of sugammadex (Ka = 3.4 × 10 M and Ka = 3.8 × 10 M-). The results of urine analysis (proton nuclear magnetic resonance), competition binding assays, and ex vivo study obtained in the absence of metabolic deactivation are in accordance with an 1:1 binding ratio of sugammadex and calabadion 2 toward rocuronium. In living rats, calabadion 2 dose-dependently and rapidly reversed all NMBAs tested. The molar potency of calabadion 2 to reverse vecuronium and rocuronium was higher

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2015 Anesthesiology

194. A comparison of effects of oral premedication with clonidine and metoprolol on intraoperative hemodynamics and surgical conditions during functional endoscopic sinus surgery. (PubMed)

with propofol 2 mg/kg. Intubation was done following vecuronium 1 mg/kg. Anesthesia was maintained with 66% N2O, 33% O2 and 1% isoflurane. The heart rate (HR) and blood pressure (BP) were measured before induction and thereafter every 15 min up to 2 h. The surgeons were asked to estimate the quality of the operative field using a pre-defined category scale with scores 1-5.Difference within the groups was analyzed using analysis of variance and post-hoc test was used to test the difference between individual

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2015 Anesthesia, essays and researches

195. Attenuation of sympathoadrenal responses and anesthetic requirement by dexmedetomidine. (PubMed)

and propofol was given until loss of verbal contact. Intubation was facilitated with vecuronium 0.1 mg/kg i.v. Anesthesia was maintained with oxygen (O2) and nitrous oxide (N2O) 33%: 67% and isoflurane. Heart rate (HR), systolic blood pressure (SBP), diastolic blood pressure (DBP) was noted at 1 min, 2 min and 5 min after intubation.For statistical analysis of the clinical data obtained, the analysis of variances (ANOVA) with paired t-test was used.Pretreatment with dexmedetomidine 1 ug/kg attenuated

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2015 Anesthesia, essays and researches

196. Comparison of esmolol and lidocaine for attenuation of cardiovascular stress response to laryngoscopy and endotracheal intubation in a Ghanaian population. (PubMed)

) and rate-pressure product (RPP) were measured before induction as baseline and after tracheal intubation at minute 1, 3, and 5. The patients were randomly allocated to receive either saline (Group C), lidocaine 1.5 mg/kg (Group L), or esmolol 2 mg/kg (Group E) (n = 40, each group). After induction of general anesthesia with thiopental 6 mg/kg and vecuronium 0.12 mg/kg, the test solution was infused 2 min before tracheal intubation. Changes in heart rate (HR), systolic blood pressure (SBP), diastolic

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2015 Anesthesia, essays and researches

197. Atracurium Besylate and other neuromuscular blocking agents promote astroglial differentiation and deplete glioblastoma stem cells (PubMed)

astroglial but not neuronal differentiation of GSCs. Functionally, Atracurium Besylate treatment significantly inhibited the clonogenic capacity of several independent patient-derived GSC neurosphere lines, a phenomenon which was largely irreversible. A second NNMB, Vecuronium, also induced GSC astrocytic differentiation while Dimethylphenylpiperazinium (DMPP), a nicotinic acetylcholine receptor (nAChR) agonist, significantly blocked Atracurium Besylate pro-differentiation activity. To investigate

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2015 Oncotarget

198. Sugammadex and rocuronium-induced anaphylaxis (PubMed)

) is associated with a relatively high rate of IgE-mediated anaphylaxis compared with other muscle relaxant agents. Sugammadex is widely used for reversal of the effects of steroidal neuromuscular blocking agents, such as rocuronium and vecuronium. Confirmed cases of allergic reactions to clinical doses of sugammadex have also been recently reported. Given these circumstances, the number of cases of hypersensitivity to either sugammadex or rocuronium is likely to increase. Thus, anesthesiologists should

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2015 Journal of anesthesia

199. Myocardial Protection and Anesthetic Agents

catheter were inserted under local anesthesia. Central venous catheter (jugular or subclavian) and esophageal heat probe were inserted after tracheal intubation. Anesthesia induction was standardized in all patients and included 1 mg/kg propofol, 1 μg/kg fentanyl and 0.1 mg/kg vecuronium bromus to facilitate endotracheal intubation. The patients were divided into two groups by computer randomization method. Group R (n=25), remifentanil group and Group D (n=25) dexmedetomidine group. In the remifentanil

2015 Clinical Trials

200. Right Way and Wrong Way: Making an Immediate Ethical/Legal Medical Decision

a bolus of vecuronium as a neuromuscular blockade, sedated, and intubated. He was also given a low-dose vasopressin for blood-pressure control. Shortly after Robert arrived in the emergency room, his daughter, his medical decision-maker, produced an advance directive documenting that her father has a do-not-resuscitate (DNR) order, and she demanded that the breathing tube and any other life-sustaining treatments be withdrawn immediately . The medical staff is very reluctant to comply with this demand

2015 Bioethics Discussion Blog

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