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Vecuronium

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1. Retraction notice to "Infusion of amino acid enriched solution hastens recovery from neuromuscular block caused by vecuronium" [Br J Anaesth 2001; 86: 814-821]. (PubMed)

Retraction notice to "Infusion of amino acid enriched solution hastens recovery from neuromuscular block caused by vecuronium" [Br J Anaesth 2001; 86: 814-821]. This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy). This article has been retracted at the request of the Editor-in-Chief of British Journal of Anaesthesia. The study is retracted for the following reasons: Statistical analysis suggests that the data may

2019 British Journal of Anaesthesia

2. Retraction notice to "Monitoring of neuromuscular block after administration of vecuronium in patients with diabetes mellitus" [Br J Anaesth 2003; 90: 480-486]. (PubMed)

Retraction notice to "Monitoring of neuromuscular block after administration of vecuronium in patients with diabetes mellitus" [Br J Anaesth 2003; 90: 480-486]. This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy). This article has been retracted at the request of the Editor-in-Chief of British Journal of Anaesthesia. The study is retracted for the following reasons: Statistical analysis suggests that the data may

2019 British Journal of Anaesthesia

3. Retraction notice to "Recoveries of post-tetanic twitch and train-of-four responses after administration of vecuronium with different inhalation anaesthetics and neuroleptanaesthesia" [Br J Anaesth 1993; 70: 402-404]. (PubMed)

Retraction notice to "Recoveries of post-tetanic twitch and train-of-four responses after administration of vecuronium with different inhalation anaesthetics and neuroleptanaesthesia" [Br J Anaesth 1993; 70: 402-404]. This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy). This article has been retracted at the request of the Editor-in-Chief of British Journal of Anaesthesia. The study is retracted for the following

2019 British Journal of Anaesthesia

4. Retraction notice to "Relationship between post-tetanic twitch and single twitch response after administration of vecuronium" [Br J Anaesth 1993; 71: 443-444]. (PubMed)

Retraction notice to "Relationship between post-tetanic twitch and single twitch response after administration of vecuronium" [Br J Anaesth 1993; 71: 443-444]. This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy). This article has been retracted at the request of the Editor-in-Chief of British Journal of Anaesthesia. The study is retracted for the following reasons: Y Saitoh provided a statement in a personal

2019 British Journal of Anaesthesia

5. Retraction notice to "Post-tetanic count and single twitch height at the onset of reflex movement after administration of vecuronium under different types of anaesthesia" [Br J Anaesth 1994; 72: 688-690]. (PubMed)

Retraction notice to "Post-tetanic count and single twitch height at the onset of reflex movement after administration of vecuronium under different types of anaesthesia" [Br J Anaesth 1994; 72: 688-690]. This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy). This article has been retracted at the request of the Editor-in-Chief of British Journal of Anaesthesia. The study is retracted for the following reasons: Y

2019 British Journal of Anaesthesia

6. Retraction notice to "Effect of tetanic stimulation on subsequent train-of-four responses at various levels of vecuronium-induced neuromuscular block" [Br J Anaesth 1994; 73: 416-417]. (PubMed)

Retraction notice to "Effect of tetanic stimulation on subsequent train-of-four responses at various levels of vecuronium-induced neuromuscular block" [Br J Anaesth 1994; 73: 416-417]. This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy). This article has been retracted at the request of the Editor-in-Chief of British Journal of Anaesthesia. The study is retracted for the following reasons: Y Saitoh provided

2019 British Journal of Anaesthesia

7. Speed of reversal of vecuronium neuromuscular block with different doses of neostigmine in anesthetized dogs. (PubMed)

Speed of reversal of vecuronium neuromuscular block with different doses of neostigmine in anesthetized dogs. Neostigmine is routinely used to reverse non-depolarizing neuromuscular block. Given its indirect mechanism, a plateau may exist whereby increasing doses of neostigmine do not result in clinical benefit. This study was designed to measure the speed of reversal of vecuronium-induced neuromuscular block in isoflurane-anesthetized dogs after the administration of three doses of neostigmine (...) as used in clinical practice.Prospective, crossover, randomized study.Seven adult, mixed-breed dogs with a mean ± standard deviation (SD) age of 2.0 ± 0.8 years and weight of 19.1 ± 9.1 kg.Dogs were anesthetized on three occasions with isoflurane and administered vecuronium (0.1 mg kg-1) intravenously (IV). The train-of-four (TOF) ratio was measured on the pelvic limb with acceleromyography. When the second twitch of the TOF had returned spontaneously, atropine (0.03 mg kg-1) and neostigmine (0.02

2018 Veterinary anaesthesia and analgesia

8. Influences of cisatracurium besylate and vecuronium bromide on muscle relaxant effects and electromyography of tracheal intubation under general anesthesia. (PubMed)

Influences of cisatracurium besylate and vecuronium bromide on muscle relaxant effects and electromyography of tracheal intubation under general anesthesia. To observe the influences of atracurium besylate and vecuronium bromide on muscle relaxant effects and electromyography of patients with tracheal intubation under general anesthesia in thyroid surgery.120 patients treated with thyroid surgery were randomly divided into group A and group V. Patients in group A were administered (...) with cisatracurium besylate combined with propofol and fentanyl for induction of tracheal intubation under general anesthesia. Patients in group V were administered with 0.10 mg/kg vecuronium bromide combined with propofol and fentanyl for induction of tracheal intubation under general anesthesia. Then, the amplitude in electromyography was observed 30-70 min after I.V. muscle relaxant medicine to record the time for patients to reach 0% TW convulsion in abductor pollicis muscle and to observe the muscle

2018 European review for medical and pharmacological sciences

9. An Observational Study of the Efficacy of Cisatracurium Compared to Vecuronium in Patients with or at Risk for ARDS. (PubMed)

An Observational Study of the Efficacy of Cisatracurium Compared to Vecuronium in Patients with or at Risk for ARDS. The neuromuscular blocking agent cisatracurium may improve mortality for patients with moderate-to-severe acute respiratory distress syndrome (ARDS). Other neuromuscular blocking agents, such as vecuronium, are commonly used and have different mechanisms of action, side effects, cost, and availability in the setting of drug shortages.To determine whether cisatracurium (...) is associated with improved outcomes when compared with vecuronium in patients at risk for and with ARDS.Using a nationally representative database, patients who were admitted to the ICU with a diagnosis of ARDS or an ARDS risk factor, received mechanical ventilation, and were treated with a continuous infusion of neuromuscular blocking agent for at least 2 days within 2 days of hospital admission were included. Patients were stratified into two groups: those who received cisatracurium or vecuronium

2017 American Journal of Respiratory and Critical Care Medicine

10. Reversal of Vecuronium-induced Neuromuscular Blockade with Low-dose Sugammadex at Train-of-four Count of Four: A Randomized Controlled Trial. (PubMed)

Reversal of Vecuronium-induced Neuromuscular Blockade with Low-dose Sugammadex at Train-of-four Count of Four: A Randomized Controlled Trial. Rocuronium-induced neuromuscular block that spontaneously recovered to a train-of-four count of four can be reversed with sugammadex 0.5 or 1.0 mg/kg. We investigated whether these doses of sugammadex can also reverse vecuronium at a similar level of block.Sixty-five patients were randomly assigned, and 64 were analyzed in this controlled, superiority (...) study. Participants received general anesthesia with propofol, sevoflurane, fentanyl, and vecuronium. Measurement of neuromuscular function was performed with acceleromyography (TOF-Watch-SX, Organon Teknika B.V., The Netherlands ). Once the block recovered spontaneously to four twitches in response to train-of-four stimulation, patients were randomly assigned to receive sugammadex 0.5, 1.0, or 2.0 mg/kg; neostigmine 0.05 mg/kg; or placebo. Time from study drug injection to normalized train-of-four

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2017 Anesthesiology

11. Evaluation of Atracurium-vecuronium Combination in Laparosocpic Surgery

Evaluation of Atracurium-vecuronium Combination in Laparosocpic Surgery Evaluation of Atracurium-vecuronium Combination in Laparosocpic Surgery - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Evaluation (...) of Atracurium-vecuronium Combination in Laparosocpic Surgery The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03371953 Recruitment Status : Not yet recruiting First Posted : December 13, 2017 Last Update Posted : December 14, 2017

2017 Clinical Trials

12. Neuronal Effects of Sugammadex in combination with Rocuronium or Vecuronium (PubMed)

Neuronal Effects of Sugammadex in combination with Rocuronium or Vecuronium Rocuronium (ROC) and Vecuronium (VEC) are the most currently used steroidal non-depolarizing neuromuscular blocking (MNB) agents. Sugammadex (SUG) rapidly reverses steroidal NMB agents after anaesthesia. The present study was conducted in order to evaluate neuronal effects of SUG alone and in combination with both ROC and VEC. Using MTT, CASP-3 activity and Western-blot we determined the toxicity of SUG, ROC or VEC

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2017 International journal of medical sciences

13. Intraoperative hemodynamics with vecuronium bromide and rocuronium for maintenance under general anesthesia. (PubMed)

Intraoperative hemodynamics with vecuronium bromide and rocuronium for maintenance under general anesthesia. The present study is undertaken to compare the hemodynamic effects using vecuronium versus rocuronium for maintenance in patients undergoing general surgical procedures.It is a prospective, randomized, and cohort study.100 patients were randomly divided into two groups. All patients were induced with 5 mg/kg of thiopentone sodium, and intubation conditions were achieved with 1.5 mg/kg (...) of suxamethonium, using a well-lubricated cuffed endotracheal tube of appropriate size. When the patient started to breathe spontaneously, they were administered either 0.6 mg/kg of rocuronium (Group A) or 0.1 mg/kg of vecuronium (Group B). Hemodynamic parameters (heart rate and mean arterial pressure [MAP]) were monitored before administering the drug; at 1, 5, 10, 15, and 20 min after the drug and at the end of the surgery.Data were compiled, analyzed and presented as frequency, proportions, mean, standard

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2016 Anesthesia, essays and researches

14. Vecuronium

Vecuronium Vecuronium Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Vecuronium Vecuronium Aka: Vecuronium , Norcuron II. Precautions (...) Used only in anesthesia, emergency and intensive care Airway and respiratory control is critical after use s do not alter Must be used with sedation and analgesia III. Indication Paralysis in IV. Preparations Vecuronium 1 mg/ml after reconstituted with 10 ml saline or sterile water to 10 mg/10 ml V. Mechanism Structurally similar to Same steroid nucleus Tertiary Nitrogen at position 2 is only difference Significantly different effects than Duration of action is half that of Hepatic excretion

2018 FP Notebook

15. Comparison of Different Induction Doses of Rocuronium and Vecuronium in Neuroanaesthesia Practice. (PubMed)

Comparison of Different Induction Doses of Rocuronium and Vecuronium in Neuroanaesthesia Practice. To evaluate the efficiency of use of rocuronium and vecuronium in different dose regimens in neuroanaesthesia practice in terms of intubation time and first additional dose requirement.Sixty-eight neurosurgery patients with intracranial mass that were operated on were included in our study. Patients were randomly divided into 4 groups according to the induction dose of neuromuscular blocker (NMB (...) ) as: Group 1: Vecuronium 0.1 mg kg(-1), Group 2: Priming, 20% of total vecuronium (0.1 mg kg(-1)) needed for induction injected 5 minutes before induction and then the rest used for induction, Group 3: Rocuronium group: 0.6 mg kg(-1), Group 4: Rocuronium with rapid-sequence induction dose (RSID) (1.2 mg kg(-1)). TOF (Train of four) test was used to decide on intubation and an additional NMB dose during surgery. Intubation quality, time from induction to intubation, time until the first additional NMB

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2016 Turkish journal of anaesthesiology and reanimation

16. [Effectiveness and safety of low-dose vecuronium on globe position of pediatric patients in ocular surgery]. (PubMed)

[Effectiveness and safety of low-dose vecuronium on globe position of pediatric patients in ocular surgery]. To test the effectiveness and safety of low-dose vecuronium (0.01 mg/kg) for correcting eccentric eye position during ocular surgery.A total of 80 ASA I-II children undergoing cataract or squint surgery were randomized into 2 groups (n = 40 each). Fentanyl and propofol were used for induction and then laryngeal mask (LMA) was inserted. 0.01 mg/kg vecuronium was administered to the low (...) -dose group (L group) and 0.08 mg/kg vecuronium for high-dose group (H group). The ToF-Watch was fixed to monitor the train of four ratio (TOFR) of adductor pollicis. Eyeball eccentricity ratio before and after dosing, TOFR, duration of eyeball in central position, duration of surgery, the time from the end of surgery to removal of LMA and oculist satisfaction were recorded.The incidence of eccentric eyeball position was nearly 100% in both groups. The eyeball eccentricity ratio was 0.30 ± 0.11 in L

2015 Zhonghua yi xue za zhi

17. The use of sugammadex for the reversal of vecuronium-induced neuromuscular block following intracranial surgery. (PubMed)

The use of sugammadex for the reversal of vecuronium-induced neuromuscular block following intracranial surgery. Total intravenous anaesthesia with propofol and remifentanil is widely used in neuroanaesthesiology and enables the quick recovery and early neurological assessment of patients. The administration of muscle relaxants carries a risk of residual relaxation following surgery. The administration of a suitable dose of sugammadex reverses the neuromuscular block irrespective of its depth (...) and has none of the side effects associated with acetylcholinesterase inhibitors. The aim of the present study was to evaluate the usefulness of sugammadex for the reversal of vecuronium-induced effects following intracranial surgery.The study involved 38 women who underwent supratentorial tumour removal. These women were randomly divided into two groups. Total intravenous anaesthesia with propofol and remifentanil using target-controlled infusion was administered according to the Schnider and Minto

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2015 Anaesthesiology intensive therapy

18. Retraction Note to: Nicorandil accelerates recovery of neuromuscular block caused by vecuronium. (PubMed)

Retraction Note to: Nicorandil accelerates recovery of neuromuscular block caused by vecuronium. Retraction Note to: Can J Anesth 2001; 1: 28–33, DOI 10.1007/BF03019810. To our readers: Further to the Expression of Concern (http://www.springer.com/medicine/anesthesiology/journal/12630) posted online, it is with considerable regret that the Canadian Journal of Anesthesia hereby retracts the above-cited article by Dr. Yoshitaka Fujii as a result of: 1) overwhelming evidence of fabrication

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2015 Canadian Journal Of Anaesthesia

19. [Efficacy and safety of sugammadex (Org 25969) in reversing moderate neuromuscular block induced by rocuronium or vecuronium in Japanese patients]. (PubMed)

[Efficacy and safety of sugammadex (Org 25969) in reversing moderate neuromuscular block induced by rocuronium or vecuronium in Japanese patients]. Efficacy and safety of sugammadex in reversing neuromuscular block induced by rocuronium or vecuronium were investgated in Japanese patients.We studied 98 Japanese patients undergoing surgery requiring general anesthesia. Patients were allocated randomly to receive intubation dose of rocuronium or vecuronium. During surgery, patients received (...) additional doses of rocuronium or vecuronium for maintenance of moderate block. At T2 reappearance sugammadex 0-4.0 mg . kg-1 was administered. The neuromuscular block was monitored with acceleromyography using TOF stimuli. Sevoflurane was administered to all treatment groups after intubation.For the rocuronium-induced neuromuscular block, the mean recovery time of the T4/T1 ratio to 0.9 decreased from 82.1 min in the placebo group to 1.8 min in the 4.0 mg . kg-1 sugammadex group. For the vecuronium

2015 Masui. The Japanese journal of anesthesiology

20. [Efficacy and safety of sugammadex (Org 25969) in reversing deep neuromuscular block induced by rocuronium or vecuronium in Japanese patients]. (PubMed)

[Efficacy and safety of sugammadex (Org 25969) in reversing deep neuromuscular block induced by rocuronium or vecuronium in Japanese patients]. Efficacy and safety of sugammadex in reversing neuromuscular block induced by rocuronium or vecuronium were investgated in Japanese patients.We studied 99 Japanese patients undergoing surgery requiring general anesthesia. Patients were allocated randomly to receive intubation dose of rocuronium or vecuronium. During surgery, patients received additional (...) dose of rocuronium or vecuronium for maintenance of deep block. At 1-2 PTC, 0.5-8.0 mg . kg-1 of sugammadex was administered. The neuromuscular block was monitored with acceleromyography using TOF stimuli. Sevoflurane was administered to all treatment groups after intubation.For the rocuronium-induced neuromuscular block, the mean recovery time of the T4/T1 ratio to 0.9 decreased from 66.9 min in the sugammadex 0.5 mg kg-1 group to 1.3 min in the sugammadex 8.0 mg kg-1 group. For the vecuronium

2015 Masui. The Japanese journal of anesthesiology

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