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Vasomotor Rhinitis

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1. Azelastine hydrochloride and fluticasone propionate (Dymista nasal spray suspension) - moderate to severe seasonal and perennial allergic rhinitis

allergic rhinitis. Seasonal allergic rhinitis especially in hay fever. 16/11/2011 (re-registration) Moderate Not applicable Yes Mometasone NASONEX 50 µg/dose Seasonal or perennial allergic rhinitis 18/07/2012 Moderate Not applicable Yes HAS - Medical, Economic and Public Health Assessment Division 7/17 Opinion 2 MSD France in adults and children above age 3. Symptomatic treatment of sinonasal polyposis in adults. (re-registration) Tixocortol PIVALONE 1000 µg/dose Pfizer Nasopharyngeal inflammatory (...) MIZOLLEN 10 mg, modified- release tablet Symptomatic treatment of seasonal allergic rhinoconjunctivitis (hay fever), perennial allergic rhinoconjunctivitis and urticaria. 16 November 2011 Moderate Not applicable Yes Rupatadine WYSTAMM 10 mg, tablet Symptomatic treatment of allergic rhinitis and chronic idiopathic urticaria in adults and adolescents (age 12 and older). 16 April 2008 Moderate Not applicable Yes *therapeutic category HAS - Medical, Economic and Public Health Assessment Division 9/17

2014 Haute Autorite de sante

2. Treatments for Seasonal Allergic Rhinitis

Preventive Services Task Force (USPSTF) Criteria for Randomized Controlled Trials (RCTs) Appendix F. McMaster Quality Assessment Scale of Harms (McHarm)ES-1 Executive Summary Background Seasonal allergic rhinitis (SAR), also known as hay fever, is an allergic reaction in the upper airways that occurs when sensitized individuals encounter airborne allergens (typically tree, grass, and weed pollens and some molds). SAR afflicts approximately 10 percent of the U.S. population, or 30 million individuals. 1,2 (...) Although pollen seasons vary across the United States, generally, tree pollens emerge in the spring, grass pollens in the summer, and weed pollens in the fall. Outdoor molds generally are prevalent in the summer and fall. SAR is distinguished from perennial allergic rhinitis (PAR), which is triggered by continuous exposure to house dust mites, animal dander, and other allergens generally found in an individual’s indoor environment. Patients may have either SAR or PAR or both (i.e., PAR with seasonal

2013 Effective Health Care Program (AHRQ)

3. Non-allergic rhinitis

and nasal polyposis, or, less commonly, tumour or foreign body. Definition Non-allergic rhinitis (NAR) refers to a group of chronic rhinitis sub-types that are not caused by allergy or infection. At least eight sub-types have been proposed, including vasomotor rhinitis (VMR [also known as 'autonomic rhinitis', 'non-allergic rhinopathy', and 'idiopathic non-allergic rhinitis']), non-allergic rhinitis with eosinophilia syndrome (NARES), atrophic rhinitis, senile rhinitis, gustatory rhinitis, drug-induced (...) Non-allergic rhinitis Non-allergic rhinitis - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Non-allergic rhinitis Last reviewed: February 2019 Last updated: January 2019 Summary Traditional triggers such as cat or dog exposure should be absent. Symptoms and examination findings can overlap between perennial allergic rhinitis and non-allergic rhinitis (NAR), with nasal turbinates swollen and beefy red, scant mucus

2019 BMJ Best Practice

4. Non-allergic rhinitis

and nasal polyposis, or, less commonly, tumour or foreign body. Definition Non-allergic rhinitis (NAR) refers to a group of chronic rhinitis sub-types that are not caused by allergy or infection. At least eight sub-types have been proposed, including vasomotor rhinitis (VMR [also known as 'autonomic rhinitis', 'non-allergic rhinopathy', and 'idiopathic non-allergic rhinitis']), non-allergic rhinitis with eosinophilia syndrome (NARES), atrophic rhinitis, senile rhinitis, gustatory rhinitis, drug-induced (...) Non-allergic rhinitis Non-allergic rhinitis - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Non-allergic rhinitis Last reviewed: February 2019 Last updated: January 2019 Summary Traditional triggers such as cat or dog exposure should be absent. Symptoms and examination findings can overlap between perennial allergic rhinitis and non-allergic rhinitis (NAR), with nasal turbinates swollen and beefy red, scant mucus

2018 BMJ Best Practice

5. Allergic Rhinitis - Guidelines for Prescribing Intranasal Corticosteroids

treatment. Irritant (non-allergic, vasomotor) rhinitis: Symptoms follow a known physical or chemical irritant - change in temperature, humidity; exercise; exposure to chemicals, odours. Patient history is important in differentiating irritant and allergic rhinitis because symptoms are similar. Identify irritant and avoid when possible. Drug-induced rhinitis : AR symptoms following start of treatment with drugs such as angiotensin-converting enzyme inhibitors, methyldopa, alpha-blockers, beta-blockers (...) in reducing symptoms of itching, sneezing, and rhinorrhea. First generation and older second generation antihistamines have little effect on nasal congestion. Fexofenadine and desloratadine have some decongestant activity. May also reduce symptoms of allergic conjunctivitis associated with AR. Little or no benefit in other forms of rhinitis (e.g., vasomotor, infectious). Effective on an as needed basis, but work best to control AR symptoms when taken regularly. When exposure to an allergen is anticipated

2017 medSask

6. ASCIA Clinical Update - Allergic Rhinitis

rhinitis can have significant impact on sleep, concentration, learning and daily function, and affect childhood behaviour and development. Patients often consider allergic rhinitis to be a nuisance, with no effective treatment. However, it can be effectively managed. The treatment of allergic rhinitis is important for the effective management of asthma. Brief history The term “hay fever” was used to describe seasonal allergic rhinitis from the late 18 th century, when the prevailing belief (...) was that the effluvium from new hay was the main cause of symptoms. In the late 19 th century Dr Charles Blackley discovered that pollen was the major cause of seasonal allergic rhinitis. The cause of allergic rhinitis symptoms are wind pollinated trees, grasses and weeds. In 1906 the term “allergy” was first used, derived from the “allos” meaning “other” or a deviation from the original state and this was combined with “rhinitis”. Therefore allergic rhinitis simply means “inflammation of the nose”. Allergic

2017 Australasian Society of Clinical Immunology and Allergy

8. Severity of nasal obstruction can predict the anxiety status of patients with allergic rhinitis but not patients with vasomotor rhinitis. (Abstract)

Severity of nasal obstruction can predict the anxiety status of patients with allergic rhinitis but not patients with vasomotor rhinitis. Allergic rhinitis (AR) is a chronic systemic allergic disease with an association reported between allergy and anxiety. The objective of the current study was therefore to investigate and retrospectively evaluate the factors that may possibly induce state and trait anxiety among patients with AR and vasomotor rhinitis (VMR).A total of 253 outpatients

2016 International forum of allergy & rhinology

9. Allergic Rhinitis

surveyed for “hay fever,” “current allergies,” and “current rhinitis” and tested for IgE specific to 19 inhalant allergens. One in 3 participants reported rhinitis symptoms within the last 12 months not associated with an upper respiratory infection. Of those with rhinitis, 52.7% demonstrated at least 1 positive allergy test. By this standard, IgE-mediated AR may affect 1 in 6 persons within the United States. The United States population is most commonly sensitized to grass pollen, dust mites (...) . Abbreviations and Definitions of Common Terms. Table 1. Abbreviations and Definitions of Common Terms. Defining Allergic Rhinitis AR is an inflammatory, IgE-mediated disease characterized by nasal congestion, rhinorrhea (nasal drainage), sneezing, and/or nasal itching. It can also be defined as inflammation of the inside lining of the nose that occurs when a person inhales something he or she is allergic to, such as animal dander or pollen; examples of the symptoms of AR are sneezing, stuffy nose, runny

2015 American Academy of Otolaryngology - Head and Neck Surgery

10. Efficacy and Safety Study of Desloratadine (MK-4117) in Japanese Participants With Seasonal Allergic Rhinitis (MK-4117-204)

Efficacy and Safety Study of Desloratadine (MK-4117) in Japanese Participants With Seasonal Allergic Rhinitis (MK-4117-204) Efficacy and Safety Study of Desloratadine (MK-4117) in Japanese Participants With Seasonal Allergic Rhinitis (MK-4117-204) - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached (...) the maximum number of saved studies (100). Please remove one or more studies before adding more. Efficacy and Safety Study of Desloratadine (MK-4117) in Japanese Participants With Seasonal Allergic Rhinitis (MK-4117-204) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02320396 Recruitment Status

2014 Clinical Trials

11. Efficacy and Safety of Ciclesonide Nasal Spray in Participants With Seasonal Allergic Rhinitis (SAR) in Russia

Efficacy and Safety of Ciclesonide Nasal Spray in Participants With Seasonal Allergic Rhinitis (SAR) in Russia Efficacy and Safety of Ciclesonide Nasal Spray in Participants With Seasonal Allergic Rhinitis (SAR) in Russia - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved (...) studies (100). Please remove one or more studies before adding more. Efficacy and Safety of Ciclesonide Nasal Spray in Participants With Seasonal Allergic Rhinitis (SAR) in Russia The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02155881 Recruitment Status : Completed First Posted : June 4, 2014 Results

2014 Clinical Trials

12. Effect of Health Promotion on Allergic Rhinitis by Infrared-C Ray Irradiation

compress with a powered heating compress Other Name: infrared-C hot compress Device: eye mask infrared-C irradiation by hot compress with a powered heating eye mask Other Name: Long Chi Drug: Xyzal Oral Product used to relieve allergy symptoms, It works by blocking histamine that body secretes during an allergic reaction. Other Name: Anti-histamine Drug: Fluticasone Furoate used to treat seasonal and perennial allergic rhinitis. It also helps to reduce the symptoms of seasonal allergic rhinitis. Other (...) Name: Steroid nasa spray Placebo Comparator: Control group received only medical treatment, e.g., Xyzal Oral Product and Fluticasone Furoate. Drug: Xyzal Oral Product used to relieve allergy symptoms, It works by blocking histamine that body secretes during an allergic reaction. Other Name: Anti-histamine Drug: Fluticasone Furoate used to treat seasonal and perennial allergic rhinitis. It also helps to reduce the symptoms of seasonal allergic rhinitis. Other Name: Steroid nasa spray Outcome

2018 Clinical Trials

13. A Comparator Study of Fluticasone Propionate Nasal Spray Verses (vs) Cetirizine in the Treatment of Seasonal Allergic Rhinitis

A Comparator Study of Fluticasone Propionate Nasal Spray Verses (vs) Cetirizine in the Treatment of Seasonal Allergic Rhinitis A Comparator Study of Fluticasone Propionate Nasal Spray Verses (vs) Cetirizine in the Treatment of Seasonal Allergic Rhinitis - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached (...) the maximum number of saved studies (100). Please remove one or more studies before adding more. A Comparator Study of Fluticasone Propionate Nasal Spray Verses (vs) Cetirizine in the Treatment of Seasonal Allergic Rhinitis The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT01916226 Recruitment Status

2013 Clinical Trials

14. Allergic Rhinitis

the patient’s continuous exposure to the offending allergen (e.g., animal, house dust mites, occupational exposures). Distinguishing prevalence rates of seasonal versus perennial allergic rhinitis is complicated by two factors: first, epidemiologic studies have focused primarily on seasonal allergic rhinitis (e.g., hay fever), and second, the symptom complex of perennial allergic rhinitis overlaps with those of seasonal allergic rhinitis, chronic sinusitis, recurrent upper respiratory infections (...) for corticosteroids. It is most effective when used regularly prior to the onset of allergic symptoms. • Intranasal antihistamines (azelastine), while effective in treating the nasal symptoms associated with seasonal and perennial rhinitis and nonallergic vasomotor rhinitis, offer no therapeutic benefit over conventional treatment and incur additional cost [II A*]. • Ocular preparations should be considered for patients with allergic conjunctivitis who are not adequately controlled with or cannot tolerate an oral

2013 University of Michigan Health System

15. Efficacy and Safety of Birch Pollen Immunotherapy in Local Allergic Rhinitis

Efficacy and Safety of Birch Pollen Immunotherapy in Local Allergic Rhinitis Efficacy and Safety of Birch Pollen Immunotherapy in Local Allergic Rhinitis - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more (...) . Efficacy and Safety of Birch Pollen Immunotherapy in Local Allergic Rhinitis (LARbirch) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT03157505 Recruitment Status : Completed First Posted : May 17, 2017 Last Update Posted : May 17, 2017 Sponsor: Medical University of Silesia Information provided

2017 Clinical Trials

16. Effect of a Probiotic on Seasonal Allergic Rhinitis Symptoms

: The purpose of the current study is to evaluate the efficacy of administering a probiotic in adult human subjects suffering from allergic rhinitis during seasonal grass pollen exposure. Condition or disease Intervention/treatment Phase Seasonal Allergic Rhinitis Dietary Supplement: Probiotic Dietary Supplement: Maltodextrin Not Applicable Detailed Description: Adult subjects with documented seasonal allergic rhinitis (SAR) to grass pollen will be assigned to placebo or probiotic groups and take either (...) : 11.31. NRC First Posted: July 31, 2012 Last Update Posted: November 20, 2013 Last Verified: November 2013 Keywords provided by Nestlé: grass pollen allergic rhinitis TNSS miniRQLQ Additional relevant MeSH terms: Layout table for MeSH terms Rhinitis Rhinitis, Allergic Rhinitis, Allergic, Seasonal Nose Diseases Respiratory Tract Diseases Respiratory Tract Infections Otorhinolaryngologic Diseases Respiratory Hypersensitivity Hypersensitivity, Immediate Hypersensitivity Immune System Diseases

2012 Clinical Trials

17. [Therapeutic effect of nasal corticosteroids combined with nasal antihistamine on vasomotor rhinitis]. (Abstract)

[Therapeutic effect of nasal corticosteroids combined with nasal antihistamine on vasomotor rhinitis]. Objective: To observe the clinical efficacy of nasal corticosteroids combined with nasal antihistamine in the treatment of vasomotor rhinitis. Method: One hundred and twenty vasomotor rhinitis patients were randomly divided into three groups including budesonide group, azelastine group, and budesonide and azelastine group with 40 cases in each. Nasal spray with nasal corticosteroids and nasal (...) (27.50, 70.00%), respectively (P<0.05). But there was no significant difference between budesonide group and azelastine group (P>0.05). Conclusion: Nasal corticosteroids and nasal antihistamine can effectively relieve the nasal symptoms of vasomotor rhinitis and improve the quality of life of patients. The effect of nasal corticosteroids was better than that of nasal antihistamine. The effect of nasal corticosteroids combined with nasal antihistamine was superior to that of single drug..Copyright©

2018 Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery Controlled trial quality: uncertain

18. [Nasal irrigation for the treatment of vasomotor rhinitis: a pilot study]. (Abstract)

[Nasal irrigation for the treatment of vasomotor rhinitis: a pilot study]. Objective: To observe the therapeutic effect of simple 3.0% saline nasal irrigation and combined treatment of 3.0% saline nasal irrigation and budesonide nasal spray for vasomotor rhinitis (VMR), and explore the long-term effect for VMR. Through examination of levels of substance P (SP) and mucin (MUC)5B in nasal lavage fluid, the mechanisms of nasal irrigation treatment for VMR was discussed. Methods: One hundred

2017 Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery Controlled trial quality: uncertain

19. A Pilot Study Investigating Clinical Responses and Biological Pathways of Azelastine/Fluticasone in Nonallergic Vasomotor Rhinitis before and after Cold Dry Air Provocation. (Abstract)

A Pilot Study Investigating Clinical Responses and Biological Pathways of Azelastine/Fluticasone in Nonallergic Vasomotor Rhinitis before and after Cold Dry Air Provocation. Nonallergic vasomotor rhinitis (NAVMR) has been considered a diagnosis by exclusion due to unknown mechanisms or lack of diagnostic biomarkers.To determine clinical responses and biological pathways in NAVMR subjects challenged to cold dry air (CDA) in an environmental exposure chamber (EEC) pre- and posttreatment

2017 International Archives of Allergy and Immunology Controlled trial quality: uncertain

20. The Use of Carbon Dioxide in the Treatment of Vasomotor Rhinitis, Hay Fever and Asthma Full Text available with Trip Pro

The Use of Carbon Dioxide in the Treatment of Vasomotor Rhinitis, Hay Fever and Asthma 19987958 2010 06 24 2010 06 24 0035-9157 24 4 1931 Feb Proceedings of the Royal Society of Medicine Proc. R. Soc. Med. The Use of Carbon Dioxide in the Treatment of Vasomotor Rhinitis, Hay Fever and Asthma. 441-2 Hurst A F AF eng Journal Article England Proc R Soc Med 7505890 0035-9157 2009 12 9 6 0 1931 2 1 0 0 1931 2 1 0 1 ppublish 19987958 PMC2182740

1931 Proceedings of the Royal Society of Medicine

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