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Uterine Inversion

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81. Guidelines for the management of pregnant and breastfeeding women in the context of Ebola virus disease

related to pregnancy, abortion, post-abortion care, breastfeeding, and sexual transmission. 12. Engagement from multiple stakeholders such as national authorities, epidemic response, UNFPA, UNAIDS and WHO is recommended to provide adequate sexual and reproductive healthcare within the context of Ebola. (Continued from previous page) Summary of evidence and considerations One study found that uterine evacuation of pregnant women with acute Lassa fever was associated with improved survival from viral

2020 World Health Organisation Guidelines

83. AIUM Practice Parameter for the Performance of an Ultrasound Examination of the Female Pelvis

on the clinical situation. Indications Indications for pelvic ultrasound include but are not limited to the following: 1. Evaluation of pelvic pain 2. Evaluation of pelvic masses 3. Evaluation of endocrine abnormalities, including polycystic ovaries 4. Evaluation of dysmenorrhea (painful menses) 5. Evaluation of amenorrhea 6. Evaluation of abnormal uterine bleeding 7. Evaluation of postmenopausal bleeding doi:10.1002/jum.15205 © 2020 by the American Institute of Ultrasound in Medicine | J Ultrasound Med 2020 (...) ; 9999:1–7 | 0278-4297 | www.aium.org8. Evaluation of delayed menses 9. Follow-up of a previously detected abnormality 10. Evaluation, monitoring, and/or treatment of patients with infertility 11. Evaluation when there is a limited clinical exami- nation of the pelvis 12. Evaluation for signs or symptoms of pelvic infection 13. Further characterization of a pelvic abnormality noted on another imaging study 14. Evaluation of congenital uterine, gonadal, and lower genital tract anomalies 15. Evaluation

2020 American Institute of Ultrasound in Medicine

85. AACE Clinical Practice Guidelines for the Diagnosis and Treatment of Postmenopausal Osteoporosis

and younger women whose fracture risk is equal to or greater than that of a 65-year-old white woman who has no additional risk factors (20,21). Q1.3. What Are the Clinical Features and Complications of Postmenopausal Osteoporosis? Q1.3.1 Low BMD Low BMD, as noted above, can be used to define post - menopausal osteoporosis. A strong inverse relationship between BMD and risk of fracture exists. Therefore, low BMD is a major indicator of fracture risk, although it is important to realize that individual

2020 American Association of Clinical Endocrinologists

86. Guidelines for the management of pregnant and breastfeeding women in the context of Ebola virus disease

related to pregnancy, abortion, post-abortion care, breastfeeding, and sexual transmission. 12. Engagement from multiple stakeholders such as national authorities, epidemic response, UNFPA, UNAIDS and WHO is recommended to provide adequate sexual and reproductive healthcare within the context of Ebola. (Continued from previous page) Summary of evidence and considerations One study found that uterine evacuation of pregnant women with acute Lassa fever was associated with improved survival from viral

2020 World Health Organisation Guidelines

87. Management of Stillbirth

and consanguinity. Fetal karyotype is important if a parent carries a balanced chromosomal rearrangement (eg, translocation or inversion) or has a mosaic karyotype. Acceptable cytogenetic specimens include amniotic fluid and a placental block taken from below the cord insertion site that includes the chorionic plate, an umbilical cord segment, or an internal fetal tissue specimen that thrives under low-oxygen tension such as costochondral or patellar tissue. Fetal skin is suboptimal . Amniocentesis for fetal (...) (predominantly infection morbidity that requires intravenous antibiotics) when compared with surgical uterine evacuation . Induction of labor has also been demonstrated to be less effective and to have higher complication rates than dilation and evacuation between 13 weeks and 24 weeks of gestation with an adjusted risk ratio of 8.5 (95% CI, 3.7–19.8) . Health care providers should weigh the risks and benefits of each strategy in a given clinical scenario and consider available institutional expertise

2020 American College of Obstetricians and Gynecologists

88. Postpartum Hemorrhage

such as uterine or ovarian artery ligation or uterine compression sutures may be utilized. If there is no response, additional considerations would include associated RPOC, adherent placentation, or even uterine inversion, and in these situations, imaging may be helpful. About 1% of third trimester deliveries are complicated by RPOC [11] and is the second most common etiology for PPH after uterine atony; although, this is typically seen in the delayed PPH population. The diagnosis of RPOC is helpful (...) . The most common cause of early PPH is related to uterine atony or lack of effective uterine contraction after delivery and is typically a clinical diagnosis in >75% of patients. It is initially treated by uterine massage and uterotonic drugs such as oxytocin, and the majority of patients respond well to these treatments. If there is no response, additional considerations would include associated RPOC, adherent placentation, or even uterine inversion, and in these situations, imaging may be helpful

2020 American College of Radiology

89. Abdominal and pelvic imaging

and Obstetric Indications 13 Adenomyosis 13 Adnexal mass 13 Endometriosis 13 Obstetric indications 14 Uterine artery embolization procedures 14 Gastrointestinal Indications 14 Appendicitis 14 Bowel obstruction 15 Constipation (Pediatric only) 15 Diverticulitis 16 Enteritis or colitis, not otherwise specified 16 Gastrointestinal bleeding 16 Inflammatory bowel disease (including Crohn’s disease and ulcerative colitis) 17 Intussusception (Pediatric only) 17 Irritable bowel syndrome (IBS) – see abdominal pain (...) of hepatobiliary and genitourinary anomalies - Ultrasound recommended for initial evaluation of pancreatic anomalies - CT abdomen and/or pelvis when additional imaging is needed to guide treatment - MRI abdomen and/or pelvis when additional imaging is needed to guide treatment - MRI preferred for evaluation of uterine anomalies - MRCP preferred for evaluation of biliary and pancreatic duct anomalies Rationale A variety of advanced structural and functional imaging modalities may be needed in the diagnosis

2020 AIM Specialty Health

90. Premature newborn care

with a neonatologist as soon as possible is recommended to provide expertise to reduce potential morbidity. Gestational age determination done within hours of birth is important for designating further care of the premature newborn. The risk of adverse outcomes varies inversely with gestational age. The New Ballard Score uses measurements of neuromuscular and physical maturity to complement the maternal history and ultrasonographic findings to estimate gestational age, although a first-trimester ultrasound remains (...) to the uterine fundus infant physical maturity score infant neuromuscular maturity score combined physical/neuromuscular score <10: gestational age <28 weeks combined physical/neuromuscular score 11 to 19: gestational age 29 to 31 weeks combined physical/neuromuscular score 20 to 24: gestational age 32 to 33 weeks combined physical/neuromuscular score 25 to 33: gestational age 34 to 36 weeks infant birth weight (appropriate for gestational age infants, AGA) spontaneous preterm labour intra-uterine infection

2018 BMJ Best Practice

91. Risk Factors for Endometrial Cancer - A review of the evidence

and criteria for grading carcinogenicity 88 Glossaries 92 Abbreviations 97 References 100 Endometrial cancer risk factors: A review of the evidence iv Figures Figure 1 Age–specific incidence of uterine cancer in Australia, by age group, 2015 17 Figure 2 Age–specific incidence of uterine cancer in Australia over time, 1982–2014, and different age groups 18 Endometrial cancer risk factors: A review of the evidence v Tables Table 1 Differences between type I and type II endometrial cancer 7 Table C.1 (...) International Agency for Research on Cancer (2015): Categories of evidence of carcinogenicity 88 Table C.2 World Cancer Research Fund/American Institute for Cancer Research (2018): Criteria for grading evidence for cancer prevention 90 Endometrial cancer risk factors: a review of the evidence 6 Introduction 1 1.1 Context There are two major types of uterine cancer: endometrial cancer and uterine sarcoma. Endometrial cancers arise in the lining of the uterus whereas uterine sarcomas develop in the muscle

2019 Cancer Australia

93. Erenumab (Aimovig) - Migraine

related to immune function, primarily infections in the future PSURs. An enhanced pre- postnatal development study was performed in cynomolgus monkey. It was agreed that this study did not identify any concerns for use during pregnancy. However, CGRP may be of importance to regulate uterine vascular resistance during pregnancy. There is a theoretical risk that CGRP inhibition may be a risk in pregnant women with risk factors for eclampsia. Based on such theoretical concerns, and also a more general

2018 European Medicines Agency - EPARs

96. The Vienna consensus: report of an expert meeting on the development of art laboratory performance indicators Full Text available with Trip Pro

. There are studies showing an increased likelihood of embryo aneuploidy in connection with aggressive ovarian stimulation, even in patients younger than 35 years, including post zygotic segregation errors and maternal segregation errors ( ; ), as well as having a negative impact on the maintenance of genomic imprints during early embryogenesis ( ; ; ). It has been shown that in patients belonging to either high or low strata of antimüllerian hormone levels an inverse correlation exists between the daily dose (...) is defined as the number of gestational sacs observed divided by the number of embryos (cleavage-stage or blastocysts) transferred ( ), or as the proportion of fetal hearts relative to the number of embryos transferred ( ). Implantation rate reflects the efficiency of the whole culture system, but it can be influenced by uterine receptivity, and by different policies for embryo transfer in different centers. LBR may be considered as the ultimate KPI for checking IVF clinic performance and defined

2018 European Society of Human Reproduction and Embryology

97. Ertugliflozin l-pyroglutamic acid / metformin hydrochloride (Segluromet) - Diabetes Mellitus, Type 2

and in vitro in liver microsomes and hepatocytes from rats, dogs, and humans. The potential for in vivo chiral inversion of ertugliflozin was also assessed in pooled plasma samples and the obtained data suggest that ertugliflozin does not undergo chiral inversion in humans. Metabolite profiles were qualitatively similar in all species with no unique human metabolites observed. Overall, glucuronidation on the hydroxy groups of the modified glucose moiety was the major metabolic pathway of ertugliflozin

2018 European Medicines Agency - EPARs

98. An International Consortium Update: Pathophysiology, Diagnosis, and Treatment of PCOS in Adolescence Full Text available with Trip Pro

a number of miRNAs dysregulated in women with PCOS. These miRNA species are involved in glycometabolism and ovarian follicle development pathways [ , ]. Interestingly, miRNA-592 has been shown to be downregulated and to be inversely related to LHCGR levels in PCOS patients [ ]. 6. Altered Sympathetic Nerve Activity An alteration in sympathetic nerve activity has been proposed to contribute to the etiology of PCOS. Indeed, many of the common clinical symptoms of PCOS, including central obesity (...) for more than 3 months), or primary amenorrhea in girls with completed puberty may suggest androgen excess [ , ]. Ovulatory dysfunction may also present as dysfunctional uterine bleeding (cycles shorter than 21 days or lasting more than 7 days) [ - ]. These menstrual disturbances may all be reflective of androgen excess [ ]. One should keep in mind that age at menarche may differ in girls with PCOS due to variable presentation, including early puberty and primary amenorrhea. Age at menarche may

2019 Pediatric Endocrine Society

99. Overweight, Obesity and Contraception

studies Some pharmacokinetic studies have shown an inverse relationship between body weight and ENG serum levels, 84,85 raising concerns about the effectiveness of the method in women with raised BMI, and the duration for which the method is effective in women with high BMI. Evidence level 2-10 Copyright ©Faculty of Sexual & Reproductive Healthcare 2019 FSRH guideline: Overweight, Obesity and Contraception In one small pharmacokinetic study 85 of the ENG implant in the first 6 months of use

2019 Faculty of Sexual & Reproductive Healthcare

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