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Uterine Inversion

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1. A large uterine leiomyoma leading to non-puerperal uterine inversion: A case report (Full text)

A large uterine leiomyoma leading to non-puerperal uterine inversion: A case report Although leiomyomas are the most common gynecologic disorders, non-puerperal uterine inversion due to leiomyoma is considered as a rare clinical problem. This condition can occur as a complication of a large sub-mucous leiomyoma that leads to dilate cervix and protrude into vagina. The patient may have several symptoms such as heavy vaginal bleeding, pelvic pain and intermittent acute urinary retention.We (...) presented a 32-year-old nulliparous woman with 17 years of unexplained infertility and diagnosis of a large vaginal prolapsed non-pedunculated leiomyoma.Haultain's procedure was used to reposition uterine inversion and remove leiomyoma through a posterior incision, using laparotomy.

2017 International Journal of Reproductive Biomedicine PubMed

2. Uterine Inversion: A Review of a Life-Threatening Obstetrical Emergency. (PubMed)

Uterine Inversion: A Review of a Life-Threatening Obstetrical Emergency. Uterine inversion is frequently accompanied by postpartum hemorrhage and hypovolemic shock. Morbidity and mortality occur in as many as 41% of cases. Prompt recognition and management are of utmost importance.The aim of this review is to describe risk factors, clinical and radiographic diagnostic criteria, and management of this rare but potentially life-threatening complication of pregnancy.A PubMed, Web of Science (...) , and CINAHL search was undertaken with no limitations on the number of years searched.There were 86 articles identified, with 25 being the basis of review. Multiple risk factors for a uterine inversion have been suggested including a morbidly adherent placenta, short umbilical cord, congenital weakness of the uterine wall or cervix, weakening of the uterine wall at the placental implantation site, fundal implantation of the placenta, uterine tumors, uterine atony, sudden uterine emptying, fetal macrosomia

2018 Obstetrical & Gynecological Survey

3. Risks and consequences of puerperal uterine inversion in the United States, 2004-2013. (PubMed)

Risks and consequences of puerperal uterine inversion in the United States, 2004-2013. Puerperal uterine inversion is a rare, potentially life-threatening obstetrical emergency. The current literature consists of small case series and a single nationwide study from Europe with only 15 cases.We aimed to define the incidence, temporal trends, and outcomes in women with uterine inversion using a nationally representative US cohort.We used the Nationwide Inpatient Sample, a 20% sample of US (...) hospital admissions, to identify all deliveries from 2004 through 2013. International Classification of Diseases, Ninth Revision diagnosis codes were used to identify cases of uterine inversion and associated adverse outcomes (maternal death, blood transfusion, maternal shock, need for surgical correction, and length of hospital stay). The incidence of uterine inversion overall and for each year of the study period was calculated with 95% confidence intervals. The case fatality and incidence of other

2017 American Journal of Obstetrics and Gynecology

4. Chronic Uterine Inversion Presenting as a Painless Vaginal Mass at 6 Months Post Partum: A Case Report (Full text)

Chronic Uterine Inversion Presenting as a Painless Vaginal Mass at 6 Months Post Partum: A Case Report Uterine inversion is an abnormal protrusion of internal surface of relaxed uterus through the vaginal orifice. Its causes can be broadly classified as puerperal and non-puerperal with puerperal uterine inversion more common than non-puerperal uterine inversion. Acute inversions occurring immediately, or within 24 hours post-partum are the most common type. Chronic Uterine Inversions (CUI (...) ) occurring more than four weeks after the delivery are rare identities. There differential diagnosis includes prolapsed fibroids and endometrial polyp. Chronic nature of these inversions makes the restoration of the normal position of the uterus per vaginal difficult contrary to acute inversions which can be reposited more easily. We hereby present a case of 28-year-old lady who presented with a painless vaginal mass at 6 months post-partum. She was diagnosed as a case of CUI based on clinical

2016 Journal of clinical and diagnostic research : JCDR PubMed

5. Non-Puerperal Uterine Inversion (Full text)

Non-Puerperal Uterine Inversion We report a case of non-puerperal uterine inversion, illustrating the correlation between MRI and pre-operation macroscopic images.

2016 Journal of the Belgian Society of Radiology PubMed

6. Uterine Inversion

Uterine Inversion Uterine Inversion Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Uterine Inversion Uterine Inversion Aka: Uterine (...) (from Bing) These images are a random sampling from a Bing search on the term "Uterine Inversion." Click on the image (or right click) to open the source website in a new browser window. Related Studies (from Trip Database) Ontology: Uterine Inversion (C0162482) Definition (MSH) A complication of OBSTETRIC LABOR in which the corpus of the UTERUS is forced completely or partially through the UTERINE CERVIX. This can occur during the late stages of labor and is associated with IMMEDIATE POSTPARTUM

2018 FP Notebook

7. Non-puerperal Uterine Inversion Presented with Hypovolemic Shock (Full text)

Non-puerperal Uterine Inversion Presented with Hypovolemic Shock We report a non-puerperal uterine inversion with nulliparous women caused by huge pedunculated submucosal fibroid. Massive bleeding from protruding mass through vagina brought the heart to stop in 42-year-old nulliparous woman. She became cardiopulmonary resuscitation survivor in emergency room and then underwent laparotomy which ended in successful myomectomy rather than hysterectomy considering her demand for future fertility (...) . Meticulous and adequate fluid therapy and transfusion was also administered to recover from hypovolemic status. Pathologic report confirmed benign submucosal fibroid with degeneration, necrosis and abscess formation. Thus, clinician should be aware of uterine inversion when encountered with huge protruding vaginal mass and consider uterus-preserving management as surgical option when the future fertility is concerned.

2016 Journal of Menopausal Medicine PubMed

8. Upside-Down and Inside-Out Signs in Uterine Inversion (Full text)

Upside-Down and Inside-Out Signs in Uterine Inversion Uterine inversion is a rare condition that is accompanied by massive hemorrhaging and shock, resulting in a maternal emergency. The diagnosis of uterine inversion is often difficult due to massive postpartum hemorrhaging. Ultrasonography is useful for the diagnosis in such conditions, but we do not often encounter typical ultrasonographic images in uterine inversion because it occurs rarely. In the present case report of uterine inversion (...) , we demonstrate the typical ultrasonographic findings of uterine inversion.

2016 Journal of clinical medicine research PubMed

9. Acute complete uterine inversion after controlled cord traction of placenta following vaginal delivery: a case report (Full text)

Acute complete uterine inversion after controlled cord traction of placenta following vaginal delivery: a case report Early recognition and active management of the third stage of labor will reduce the risks associated with uterine inversion. All staff members in the maternal unit should be updated with Green-Top guidelines No. 52 and be appropriately trained in the PROMPT course to provide a standardized approach in obstetric emergencies.

2016 Clinical Case Reports PubMed

10. Puerperal uterine inversion managed by the uterine balloon tamponade (Full text)

Puerperal uterine inversion managed by the uterine balloon tamponade The uterine inversion is a rare and severe puerperal complication. Uncontrolled cord traction and uterine expression are the common causes described. We report a case of uterine inversion stage III caused by poor management of the third stage of labor. It was about a 20 years old primigravida referred in our unit for postpartum hemorrhage due to uterine atony. After manual reduction of the uterus, the use of intra uterine (...) balloon tamponade helped to stop the hemorrhage. The uterine inversion is a rare complication that may cause maternal death. The diagnosis is clinical and its management must be immediate to avoid maternal complications.

2015 The Pan African medical journal PubMed

11. Successful Reduction of Acute Puerperal Uterine Inversion with the Use of a Bakri Postpartum Balloon (Full text)

Successful Reduction of Acute Puerperal Uterine Inversion with the Use of a Bakri Postpartum Balloon Uterine inversion is a state wherein the endometrial surface is inverted. Although this condition may be observed in nonpregnant women, it most commonly develops at the time of delivery. In the present case, a 37-year-old woman without any remarkable history developed acute puerperal uterine inversion after the successful induction of labor. Following the delivery, she complained twice of severe (...) lower abdominal pain; subsequently, hemorrhage was noted at the site of partial detachment of the placenta. These findings led to a diagnosis of placenta accreta, and the patient developed a state of shock. A Bakri postpartum balloon was inserted into the uterine cavity under ultrasonographic guidance and was filled with physiological saline for treatment of this condition. With this procedure, the uterine inversion was completely reduced and the hemorrhage was stopped. Moreover, no reinversion

2015 Case reports in obstetrics and gynecology PubMed

12. Time from neuraxial anesthesia placement to delivery is inversely proportional to umbilical arterial cord pH at scheduled cesarean delivery. (PubMed)

Time from neuraxial anesthesia placement to delivery is inversely proportional to umbilical arterial cord pH at scheduled cesarean delivery. Neuraxial block-related hypotension and maternal obesity contribute to uterine hypoperfusion and decreased umbilical arterial pH at cesarean delivery. Between the time of anesthesia placement and delivery, the fetus may be exposed to a hypoperfused uterine environment without surgeon awareness of fetal compromise.We sought to evaluate neonatal umbilical (...) arterial pH according to predelivery time intervals at scheduled term cesarean.We performed a retrospective cohort study of cesarean deliveries between September 2014 and February 2017. Singleton gestations undergoing scheduled cesarean delivery under spinal anesthesia between 37 and 41 weeks with a reassuring preoperative nonstress test were included. Time intervals between operative room entry, spinal anesthesia placement, skin incision, uterine incision, and delivery were calculated. The primary

2019 American Journal of Obstetrics and Gynecology

13. Inversely and adaptively planned interstitial brachytherapy: A single implant approach. (PubMed)

Inversely and adaptively planned interstitial brachytherapy: A single implant approach. To evaluate the efficacy, feasibility and safety of image-based, inversely and adaptively planned high-dose rate interstitial brachytherapy (HDR-ISBT) to treat advanced primary or recurrent gynecologic malignancy in a single implant, three-consecutive-day regimen.Clinical demographics and outcome data were abstracted from all patients with primary and recurrent gynecologic malignancies who received HDR-ISBT (...) boost from 2014 to 2017. Treatment consisted of a single implant (~7 Gy × 4 fractions) of interstitial needles using the Syed-Neblett template over a three-day hospital admission. CT-based (3D) simulation with inverse and adaptive planning was utilized for each fraction. MR prior to and MR immediately after external beam therapy were fused for HDR-ISBT target delineation.Forty women with an overall median follow-up of 18 months (range: 6-54 months) received an HDR-ISBT boost. Of the 30 primary cases

2018 Gynecologic Oncology

14. Classics revisited: Miguel Fernández on germ layer inversion and specific polyembryony in armadillos. (PubMed)

Classics revisited: Miguel Fernández on germ layer inversion and specific polyembryony in armadillos. Miguel Fernández was an Argentinian zoologist who published the first account of obligate polyembryony in armadillos. His contribution is here discussed in relation to his contemporaries, Newman and Patterson, and more recent work.Fernandez worked on the mulita (Dasypus hybridus). He was able to get early stages before twinning occurred and show it was preceded by inversion of the germ layers (...) . By the primitive streak stage there were separate embryonic shields and partition of the amnion. There was, however, a single exocoelom and all embryos were enclosed in a common set of membranes comprising chorion towards the attachment site in the uterine fundus and inverted yolk sac on the opposite face. He showed that monozygotic twinning did not occur in another armadillo, the peludo (Chaetophractus villosus).Fernández's work represented a major breakthrough in understanding how twinning occurred

2018 Placenta

15. Inversion utérine: à propos d’un cas (Full text)

Inversion utérine: à propos d’un cas Uterine inversion is a rare but potentially serious complication of labour characterized by "glove-finger" introflexion of the uterine body protruding into the vagina or out of the vulva. This disease commonly occurs just after delivery and it is characterized by severe pain associated with hemorrhagic shock. The diagnosis is essentially based on clinical examination and must be immediate in order to allow quick reinversion before the formation (...) of a constriction ring. Mortality rate is low if patients are early diagnosed and treated. Uterine inversion does not seem to affect the obstetrical prognosis. Contributing factors mainly include uterine hypotonia associated with fundal placenta causing depression of the uterine fundus in case of inappropriate maneuvers (pulling on the umbilical cord, uterine expression). Reinversion should be quick associated with resuscitation measures (shock resuscitation). It is based on several manual methods consisting

2018 The Pan African medical journal PubMed

16. Chemotherapy, Radiation, or Combination Therapy for Stage III Uterine Cancer. (PubMed)

Chemotherapy, Radiation, or Combination Therapy for Stage III Uterine Cancer. To compare the outcomes of women with stage III uterine cancer treated with chemotherapy alone, external beam radiation alone, and combination chemotherapy and radiation.The National Cancer Database was used to identify women with stage III endometrioid, serous, and clear cell uterine cancer treated with either chemotherapy (with or without vaginal brachytherapy) alone, external beam radiation (with or without (...) brachytherapy), or combination chemotherapy and external beam radiation (with or without vaginal brachytherapy) from 2004 to 2015. Survival was estimated using Cox proportional hazards models and adjusted survival curves after propensity score analysis using inverse probability of treatment weighting to balance the clinical and demographic characteristics between the cohorts.Of the 20,873 patients identified, 9,456 (45.3%) received chemotherapy alone, 2,417 (11.6%) were treated with radiation alone

2019 Obstetrics and Gynecology

17. MY (Matsubara-Yano) uterine compression suture to prevent acute recurrence of uterine inversion. (PubMed)

MY (Matsubara-Yano) uterine compression suture to prevent acute recurrence of uterine inversion. 22881712 2013 07 16 2014 11 20 1600-0412 92 6 2013 Jun Acta obstetricia et gynecologica Scandinavica Acta Obstet Gynecol Scand MY (Matsubara-Yano) uterine compression suture to prevent acute recurrence of uterine inversion. 734-5 10.1111/j.1600-0412.2012.01513.x Matsubara Shigeki S Baba Yosuke Y eng Letter 2012 09 18 United States Acta Obstet Gynecol Scand 0370343 0001-6349 IM Female Humans (...) Secondary Prevention Suture Techniques Uterine Inversion surgery Uterus surgery 2012 8 14 6 0 2012 8 14 6 0 2013 7 17 6 0 ppublish 22881712 10.1111/j.1600-0412.2012.01513.x

2012 Acta Obstetricia et Gynecologica Scandinavica

18. Primary extra-uterine and extra-ovarian mullerian adenosarcoma: case report and literature review. (Full text)

Primary extra-uterine and extra-ovarian mullerian adenosarcoma: case report and literature review. Extra-uterine mullerian adenosarcomas have varying biological behaviours depending on the presence of endometriosis or sarcomatous overgrowth. These behaviours manifest according to the tumours' histological characteristics and sites of origin. The best treatment and oncologic outcome have not been clarified because only a few cases of extra-uterine and extra-ovarian adenosarcoma have been (...) to the progressive poor condition, the patient died four months after diagnosis. Histological slides were reviewed by external expert pathologists and the final diagnosis was of extra-genital adenosarcoma with sarcomatous overgrowth. Furthermore, we also collected and analysed articles written in English regarding extra-uterine and extra-ovarian adenosarcomas published between January 1974 and October 2016. PubMed was used as a database for this search. Clinical and pathological characteristics, treatments

2018 BMC Cancer PubMed

19. Genomic profiling identifies GPC5 amplification in association with sarcomatous transformation in a subset of uterine carcinosarcomas (Full text)

Genomic profiling identifies GPC5 amplification in association with sarcomatous transformation in a subset of uterine carcinosarcomas Uterine carcinosarcoma, also known as Malignant Mixed Müllerian Tumour, is a high-grade biphasic neoplasm composed of sarcomatous elements thought to originate via transdifferentiation from high-grade endometrial carcinoma. To identify molecular factors contributing to the histogenesis of this tumour, we analyzed DNA extracted from matched carcinoma and sarcoma (...) components from 12 cases of carcinosarcoma by a molecular inversion probe microarray to assess genomic copy number alterations (CNAs) and allelic imbalances. Widespread CNAs were identified in tumours with serous histology in the carcinoma component (9/12), while the remaining three cases with endometrioid carcinoma were near-diploid. Quantification of the extent of genomic aberrations revealed a significant increase in sarcoma relative to carcinoma in tumours with well-delineated histologic components

2018 The Journal of Pathology: Clinical Research PubMed

20. Uterine Foxl2 regulates the adherence of the Trophectoderm cells to the endometrial epithelium (Full text)

of the Wnt/Fzd and apoptotic pathways, both of which are involved in uterine receptivity. Furthermore, FOXL2 expression was inversely correlated with G-protein signaling protein 2 (Rgs2) and cytokine expression.These results suggest that FOXL2 interferes with embryo attachment. Better understanding of the function of FOXL2 in the uterus would possibly suggest novel strategies for treatment of infertility attributed to repeated implantation failure. (...) Uterine Foxl2 regulates the adherence of the Trophectoderm cells to the endometrial epithelium Forkhead Transcription Factor L2 (FOXL2) is a member of the forkhead family with important roles in reproduction. Recent studies showed that FOXL2 is expressed in human and bovine endometrium and that its levels fluctuate during pregnancy. In this study, we aimed at evaluating the expression and function of FOXL2 in embryo implantation.Mouse uteri at different days of pregnancy were isolated

2018 Reproductive biology and endocrinology : RB&E PubMed

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