How to Trip Rapid Review

Step 1: Select articles relevant to your search (remember the system is only optimised for single intervention studies)

Step 2: press

Step 3: review the result, and maybe amend the or if you know better! If we're unsure of the overall sentiment of the trial we will display the conclusion under the article title. We then require you to tell us what the correct sentiment is.

1,779 results for

Urine Uric Acid

by
...
Latest & greatest
Alerts

Export results

Use check boxes to select individual results below

SmartSearch available

Trip's SmartSearch engine has discovered connected searches & results. Click to show

141. A specific enzyme defect in gout associated with overproduction of uric acid. (PubMed)

Hypoxanthines 268B43MJ25 Uric Acid 5Z93L87A1R Guanine EC 2.4.1.- Glucosyltransferases IM Adult Diphosphates Erythrocytes enzymology Glucosyltransferases metabolism Gout metabolism Guanine Hot Temperature Humans Hypoxanthines In Vitro Techniques Leukocytes enzymology Male Middle Aged Molecular Biology Mutation Purine-Pyrimidine Metabolism, Inborn Errors Uric Acid biosynthesis blood urine 1967 6 1 1967 6 1 0 1 1967 6 1 0 0 ppublish 4291947 PMC224540 Science. 1967 Mar 31;155(3770):1682-4 6020292 Proc Soc Exp (...) A specific enzyme defect in gout associated with overproduction of uric acid. 4291947 1967 10 13 2018 11 13 0027-8424 57 6 1967 Jun Proceedings of the National Academy of Sciences of the United States of America Proc. Natl. Acad. Sci. U.S.A. A specific enzyme defect in gout associated with overproduction of uric acid. 1735-9 Kelley W N WN Rosenbloom F M FM Henderson J F JF Seegmiller J E JE eng Journal Article United States Proc Natl Acad Sci U S A 7505876 0027-8424 0 Diphosphates 0

Full Text available with Trip Pro

1967 Proceedings of the National Academy of Sciences of the United States of America

142. Overproduction of Uric Acid in Hypoxanthine-Guanine Phosphoribosyltransferase Deficiency: CONTRIBUTION BY IMPAIRED PURINE SALVAGE (PubMed)

phosphoribosyltransferase-deficient subjects and Lesch-Nyhan patients show increases of 18.6+/-10.8 and 17.3+/-11.8 mmol/g creatinine, respectively. Of the observed rise in purine exretion in control subjects, 40% occurs from inosine excretion and 32% occurs from oxypurine excretion. The rise in total purine excretion with Lesch-Nyhan syndrome is almost entirely accounted for by an elevated uric acid excretion. Increases in urine radioactivity after fructose infusion are distributed in those purines that are excreted (...) Overproduction of Uric Acid in Hypoxanthine-Guanine Phosphoribosyltransferase Deficiency: CONTRIBUTION BY IMPAIRED PURINE SALVAGE The contribution of reduced purine salvage to the hyperuricemia associated with hypoxanthine-guanine phosphoribosyltransferase deficiency was measured by the intravenous administration of tracer doses of [8-(14)C]adenine to nine patients with normal enzyme activity, three patients with a partial deficiency of hypoxanthine-guanine phosphoribosyltransferase, and six

Full Text available with Trip Pro

1979 Journal of Clinical Investigation

143. THE EFFECT OF SALICYLATES AND ADRENOCORTICOTROPIC HORMONE UPON THE MISCIBLE POOL OF URIC ACID IN GOUT (PubMed)

-2 Adrenocorticotropic Hormone OM Adrenocorticotropic Hormone Body Fluids Gout Humans Salicylates Uric Acid Urine 5019:27523:3:99:213:257 ACTH GOUT SALICYL COMPOUNDS URINE 1950 8 1 1950 8 1 0 1 1950 8 1 0 0 ppublish 15436881 10.1172/JCI102343 PMC436151 J Biol Chem. 1949 Nov;181(1):183-93 15390405 Science. 1949 Mar 18;109(2829):280-1 17775053 (...) THE EFFECT OF SALICYLATES AND ADRENOCORTICOTROPIC HORMONE UPON THE MISCIBLE POOL OF URIC ACID IN GOUT 15436881 2004 09 30 2018 12 01 0021-9738 29 8 1950 Aug The Journal of clinical investigation J. Clin. Invest. The effect of salicylates and adrenocorticotropic hormone upon the miscible pool of uric acid in gout. 1104-11 BENEDICT J D JD FORSHAM P H PH ROCHE M M SOLOWAY S S STETTEN D D Jr eng Journal Article United States J Clin Invest 7802877 0021-9738 0 Salicylates 268B43MJ25 Uric Acid 9002-60

Full Text available with Trip Pro

1950 Journal of Clinical Investigation

144. Effect of ACTH and Sodium Salicylate on the Urinary Uric Acid: Creatinine Ratio, and Circulating Eosinophils in Man (PubMed)

Creatinine O414PZ4LPZ Salicylic Acid WIQ1H85SYP Sodium Salicylate OM Adrenocorticotropic Hormone pharmacology Arthritis Arthritis, Rheumatoid metabolism Creatinine Eosinophils drug effects Gout metabolism Humans Male Osteoarthritis metabolism Salicylic Acid pharmacology Sodium Salicylate Uric Acid urine 5425:46618:8:46:161:201:333:412:486 ACTH/effects ARTHRITIS, RHEUMATOID/metabolism in EOSINOPHILS/effect of drugs on GOUT/metabolism in OSTEOARTHRITIS/metabolism in SALICYLIC ACID/effects URIC ACID (...) Effect of ACTH and Sodium Salicylate on the Urinary Uric Acid: Creatinine Ratio, and Circulating Eosinophils in Man 13125229 2003 05 01 2018 12 01 0003-4967 12 4 1953 Dec Annals of the rheumatic diseases Ann. Rheum. Dis. Effect of ACTH and sodium salicylate on the urinary uric acid: creatinine ratio, and circulating eosinophils in man. 296-300 MARSON F G FG eng Journal Article England Ann Rheum Dis 0372355 0003-4967 268B43MJ25 Uric Acid 9002-60-2 Adrenocorticotropic Hormone AYI8EX34EU

Full Text available with Trip Pro

1953 Annals of the Rheumatic Diseases

145. ON THE MECHANISM OF OVERPRODUCTION OF URIC ACID IN PATIENTS WITH PRIMARY GOUT (PubMed)

ON THE MECHANISM OF OVERPRODUCTION OF URIC ACID IN PATIENTS WITH PRIMARY GOUT 13539198 2000 07 01 2018 12 01 0021-9738 37 4 1958 Apr The Journal of clinical investigation J. Clin. Invest. On the mechanism of overproduction of uric acid in patients with primary gout. 579-90 WYNGAARDEN J B JB BLAIR A E AE HILLEY L L eng Journal Article United States J Clin Invest 7802877 0021-9738 268B43MJ25 Uric Acid OM Gout urine Humans Hyperuricemia Uric Acid metabolism 5834:31738:254:621 GOUT/urine in URIC (...) ACID/metabolism 1958 4 1 1958 4 1 0 1 1958 4 1 0 0 ppublish 13539198 10.1172/JCI103641 PMC293124 J Biol Chem. 1954 Jul;209(1):23-39 13192056 Metabolism. 1957 May;6(3):244-68 13430358 Arch Biochem Biophys. 1955 May;56(1):184-95 14377564 Biochem J. 1952 Jan;50(3):404-7 14915965 J Biol Chem. 1957 Jan;224(1):423-34 13398418 Am J Med. 1953 Dec;15(6):845-6 13104455 J Biol Chem. 1953 May;202(1):241-52 13061451 Metabolism. 1952 Jan;1(1):3-12 14890550 Am J Med. 1957 Oct;23(4):600-22 13469831 J Biol Chem

Full Text available with Trip Pro

1958 Journal of Clinical Investigation

146. Pattern of Uric-acid Excretion During a Leukaemic Remission (PubMed)

Pattern of Uric-acid Excretion During a Leukaemic Remission 13816601 1998 11 01 2018 12 01 0007-1447 1 5178 1960 Apr 02 British medical journal Br Med J Pattern of uric-acid excretion during a leukaemic remission. 1027-9 DICKINSON C J CJ eng Journal Article England Br Med J 0372673 0007-1447 268B43MJ25 Uric Acid OM Biological Transport Body Fluids Humans Leukemia urine Uric Acid urine LEUKEMIA/urine URIC ACID/urine 1960 4 2 1960 4 2 0 1 1960 4 2 0 0 ppublish 13816601 PMC1967518 Scand J Clin Lab

Full Text available with Trip Pro

1960 British medical journal

147. CHANGES IN SERUM AND URINARY URIC ACID WITH THE DEVELOPMENT OF SYMPTOMATIC GOUT (PubMed)

CHANGES IN SERUM AND URINARY URIC ACID WITH THE DEVELOPMENT OF SYMPTOMATIC GOUT 14083171 1996 12 01 2018 12 01 0021-9738 42 1963 Nov The Journal of clinical investigation J. Clin. Invest. CHANGES IN SERUM AND URINARY URIC ACID WITH THE DEVELOPMENT OF SYMPTOMATIC GOUT. 1835-9 AYVAZIAN J H JH AYVAZIAN I F IF eng Journal Article United States J Clin Invest 7802877 0021-9738 268B43MJ25 Uric Acid OM Blood Chemical Analysis Body Fluids Gout Humans Uric Acid Urine BLOOD CHEMICAL ANALYSIS GOUT URIC (...) ACID URINE 1963 11 1 1963 11 1 0 1 1963 11 1 0 0 ppublish 14083171 10.1172/JCI104867 PMC289465 N Engl J Med. 1963 Apr 11;268:821-7 concl 13987630 Postgrad Med. 1954 Mar;15(3):255-64 13133834 J Biol Chem. 1954 Oct;210(2):923-32 13211630 N Engl J Med. 1960 Nov 17;263:999-1002 13685390 Minn Med. 1959 Aug;42(8):1044-52 13674316 N Engl J Med. 1959 Apr 30;260(18):893-900 13657306 J Clin Invest. 1961 Nov;40:1961-6 13863518 Perspect Biol Med. 1959;2(2):185-96 13623382 J Clin Invest. 1959 Nov;38:1890-8

Full Text available with Trip Pro

1963 Journal of Clinical Investigation

148. Uric acid excretion in the relatives of patients with gout. (PubMed)

Uric acid excretion in the relatives of patients with gout. 4916770 1970 10 17 2018 11 13 0003-4967 29 4 1970 Jul Annals of the rheumatic diseases Ann. Rheum. Dis. Uric acid excretion in the relatives of patients with gout. 397-400 Scott J T JT Pollard A C AC eng Journal Article Review England Ann Rheum Dis 0372355 0003-4967 268B43MJ25 Uric Acid AYI8EX34EU Creatinine IM Creatinine urine Female Gout blood genetics urine Humans Male Sex Factors Uric Acid blood urine 11 1970 7 1 1970 7 1 0 1 1970

Full Text available with Trip Pro

1970 Annals of the Rheumatic Diseases

149. Uric acid metabolism in starvation. (PubMed)

Uric acid metabolism in starvation. 5476683 1970 12 22 2018 11 13 0003-4967 29 5 1970 Sep Annals of the rheumatic diseases Ann. Rheum. Dis. Uric acid metabolism in starvation. 553-5 Lloyd-Mostyn R H RH Lord P S PS Glover R R West C C Gilliland I C IC eng Journal Article England Ann Rheum Dis 0372355 0003-4967 268B43MJ25 Uric Acid 63CZ7GJN5I Allopurinol IM Allopurinol adverse effects therapeutic use Female Gout Humans Male Obesity therapy Starvation metabolism Uric Acid blood metabolism urine

Full Text available with Trip Pro

1970 Annals of the Rheumatic Diseases

150. C14 studies of uric acid turnover. (PubMed)

C14 studies of uric acid turnover. 5677169 1968 11 06 2013 11 21 0003-4967 27 5 1968 Sep Annals of the rheumatic diseases Ann. Rheum. Dis. C14 studies of uric acid turnover. 476-7 Scott J T JT Arnot R R Glass H I HI Holloway V P VP eng Journal Article England Ann Rheum Dis 0372355 0003-4967 0 Carbon Isotopes 268B43MJ25 Uric Acid 63CZ7GJN5I Allopurinol IM Acute Kidney Injury Allopurinol therapeutic use Carbon Isotopes Gout drug therapy Humans Mathematics Uric Acid urine 1968 9 1 1968 9 1 0 1

Full Text available with Trip Pro

1968 Annals of the Rheumatic Diseases

151. Metabolic studies on the formation of calcium oxalate stones, with special emphasis on vitamin B6 and uric acid metabolism. (PubMed)

Med 7505398 0028-7091 0 Oxalates 268B43MJ25 Uric Acid SY7Q814VUP Calcium IM Calcium urine Female Humans Male Oxalates urine Uric Acid metabolism Urinary Calculi etiology Vitamin B 6 Deficiency complications 1968 1 1 1968 1 1 0 1 1968 1 1 0 0 ppublish 5239150 PMC1749976 Proc Soc Exp Biol Med. 1951 Jul;77(3):399-401 14864603 Am J Clin Nutr. 1960 Nov-Dec;8:812-6 13704750 Clin Sci (Lond). 1957 Aug;16(3):405-11 13473154 J Lab Clin Med. 1959 Dec;54:903-13 14416793 Clin Chem. 1963 Jun;9:334-9 13934121 J (...) Metabolic studies on the formation of calcium oxalate stones, with special emphasis on vitamin B6 and uric acid metabolism. 5239150 1968 06 07 2018 11 13 0028-7091 44 1 1968 Jan Bulletin of the New York Academy of Medicine Bull N Y Acad Med Metabolic studies on the formation of calcium oxalate stones, with special emphasis on vitamin B6 and uric acid metabolism. 28-44 Mayer G G GG Chase T T Farvar B B Waidh M A MA Longo F F Karp F F Zinsser H H HH eng Journal Article United States Bull N Y Acad

Full Text available with Trip Pro

1968 Bulletin of the New York Academy of Medicine

152. Studies of uric acid pool size and turnover rate. (PubMed)

Hypertension complications Male Mathematics Metabolic Clearance Rate Middle Aged Uric Acid blood metabolism urine 1969 7 1 1969 7 1 0 1 1969 7 1 0 0 ppublish 5794063 PMC1010504 Lancet. 1966 Jan 1;1(7427):15-8 4159153 Strahlentherapie Sonderb. 1968;67:223-33 5719123 J Clin Invest. 1951 Aug;30(8):879-88 14861310 J Biol Chem. 1952 May;196(1):179-84 12980954 Biochem J. 1954 Nov;58(3):426-37 13208633 J Clin Invest. 1961 Jul;40:1304-14 13749616 Biophys J. 1962 May;2:275-87 13867975 J Biol Chem. 1949 Nov;181(1 (...) Studies of uric acid pool size and turnover rate. 5794063 1969 08 30 2018 11 13 0003-4967 28 4 1969 Jul Annals of the rheumatic diseases Ann. Rheum. Dis. Studies of uric acid pool size and turnover rate. 366-73 Scott J T JT Holloway V P VP Glass H I HI Arnot R N RN eng Journal Article England Ann Rheum Dis 0372355 0003-4967 0 Carbon Isotopes 268B43MJ25 Uric Acid 63CZ7GJN5I Allopurinol IM Adolescent Adult Aged Allopurinol therapeutic use Carbon Isotopes Female Gout drug therapy metabolism Humans

Full Text available with Trip Pro

1969 Annals of the Rheumatic Diseases

153. Uric acid clearance in patients with gout and normal subjects. (PubMed)

Rate Middle Aged Uric Acid blood metabolism urine 1971 5 1 1971 5 1 0 1 1971 5 1 0 0 ppublish 5090245 PMC1005769 Ann Rheum Dis. 1970 Jul;29(4):397-400 4916770 Am J Med. 1969 Oct;47(4):575-92 4898522 J Lab Clin Med. 1959 Dec;54:903-13 14416793 Aust J Exp Biol Med Sci. 1958 Aug;36(4):383-94 13607346 J Clin Invest. 1961 Jul;40:1304-14 13749616 J Clin Invest. 1959 Nov;38:1890-8 14427889 J Pediatr. 1968 Oct;73(4):583-92 5678000 J Clin Invest. 1962 Nov;41(11):1955-63 16695885 Proc R Soc Med. 1969 Aug;62 (...) Uric acid clearance in patients with gout and normal subjects. 5090245 1971 08 13 2018 11 13 0003-4967 30 3 1971 May Annals of the rheumatic diseases Ann. Rheum. Dis. Uric acid clearance in patients with gout and normal subjects. 285-9 Snaith M L ML Scott J T JT eng Journal Article England Ann Rheum Dis 0372355 0003-4967 268B43MJ25 Uric Acid AYI8EX34EU Creatinine IM Adult Aged Body Height Body Weight Creatinine metabolism Female Gout metabolism Humans Kidney metabolism Male Metabolic Clearance

Full Text available with Trip Pro

1971 Annals of the Rheumatic Diseases

154. The metabolic basis of uric acid stone formation. (PubMed)

The metabolic basis of uric acid stone formation. 5124821 1972 02 11 2013 11 21 0264-6021 122 1 1971 Mar The Biochemical journal Biochem. J. The metabolic basis of uric acid stone formation. 9P Wrong O M OM eng Journal Article England Biochem J 2984726R 0264-6021 0 Bicarbonates 0 Citrates 268B43MJ25 Uric Acid IM Adult Bicarbonates therapeutic use Chemical Precipitation Citrates therapeutic use Humans Hydrogen-Ion Concentration Uric Acid urine Urinary Calculi metabolism prevention & control 1971

Full Text available with Trip Pro

1971 Biochemical Journal

155. Uric acid excretion and surgery. (PubMed)

Uric acid excretion and surgery. 5032447 1972 08 09 2018 11 13 0003-4967 31 3 1972 May Annals of the rheumatic diseases Ann. Rheum. Dis. Uric acid excretion and surgery. 162-5 Snaith M L ML Scott J T JT eng Journal Article England Ann Rheum Dis 0372355 0003-4967 268B43MJ25 Uric Acid AYI8EX34EU Creatinine IM Adult Aged Creatinine urine Female Gout etiology Humans Kidney metabolism Male Metabolic Clearance Rate Middle Aged Postoperative Complications Time Factors Uric Acid blood metabolism urine

Full Text available with Trip Pro

1972 Annals of the Rheumatic Diseases

156. Fractional excretion of uric acid in infancy and childhood: Index of tubular maturation (PubMed)

Child Child, Preschool Creatinine urine Female Glomerular Filtration Rate Humans Hydrogen-Ion Concentration Infant Infant, Newborn Kidney Tubules growth & development Male Regression Analysis Uric Acid blood urine Urine 1974 11 1 1974 11 1 0 1 1974 11 1 0 0 ppublish 4441122 PMC1649243 Arch Dis Child. 1971 Jun;46(247):356-62 5104539 N Engl J Med. 1963 Mar 28;268:712-6 contd 13987629 N Engl J Med. 1971 May 27;284(21):1193-6 4929385 Nephron. 1964;1:144-57 14246792 Pediatrics. 1968 Sep;42(3):395-404 (...) Fractional excretion of uric acid in infancy and childhood: Index of tubular maturation 4441122 1975 02 27 2018 11 13 1468-2044 49 11 1974 Nov Archives of disease in childhood Arch. Dis. Child. Fractional excretion of uric acid in infancy and childhood. Index of tubular maturation. 878-82 Passwell J H JH Modan M M Brish M M Orda S S Boichis H H eng Journal Article England Arch Dis Child 0372434 0003-9888 268B43MJ25 Uric Acid AYI8EX34EU Creatinine IM Age Factors Birth Weight Body Surface Area

Full Text available with Trip Pro

1974 Archives of Disease in Childhood

157. Inborn enzymatic defect as the probable cause of the formation of renal stones consisting of uric acid (PubMed)

Inborn enzymatic defect as the probable cause of the formation of renal stones consisting of uric acid In four persons of one family the existence of an enzymatic defect, presumably consisting of a deficiency of glutaminase in the cells of the renal tubules, is postulated, and is implied by a reduced elimination of ammonia in the urine, by a relatively low urinary pH, and by its increased titratable acidity. The most characteristic clinical symptom is irritation of the distal part (...) of the urinary tract, connected with numerous crystals of uric acid appearing in the urinary sediment. The elimination of uric acid is normal, or even reduced, and the level of uric acid in the blood serum is also within normal limits. After the administration of glutaminic acid elimination of ammonia is further decreased and the quantity of uric acid crystals is increased. Loading with glutaminic acid may also cause an attack of renal pain in the individual suffering from this defect but the administration

Full Text available with Trip Pro

1965 Journal of Clinical Pathology

158. Localization and Pyrazinamide Inhibition of Distal Transtubular Movement of Uric Acid-2-C14 with a Modified Stop-Flow Technique (PubMed)

Isotopes 268B43MJ25 Uric Acid 2KNI5N06TI Pyrazinamide 9005-80-5 Inulin AYI8EX34EU Creatinine MU72812GK0 Creatine Y79XT83BJ9 p-Aminohippuric Acid OM Biological Transport Carbon Isotopes Creatine Creatinine Dogs Fluids and Secretions Inulin Kidney Tubules Physiology Pyrazinamide Renal Artery Research Uric Acid Urine p-Aminohippuric Acid AMINOHIPPURIC ACID BIOLOGICAL TRANSPORT CARBON ISOTOPES CREATINE AND CREATININE DOGS EXCRETION EXPERIMENTAL LAB STUDY INULIN KIDNEY TUBULES PHYSIOLOGY PYRAZINAMIDE RENAL (...) ARTERY URIC ACID URINE 1965 5 1 1965 5 1 0 1 1965 5 1 0 0 ppublish 14276129 10.1172/JCI105184 PMC292548 Am J Physiol. 1960 Jul;199:9-12 14414436 J Clin Invest. 1959 Oct;38:1778-81 13830462 Am J Physiol. 1959 Sep;197:601-3 14408687 J Clin Invest. 1963 Aug;42:1330-9 14060403 J Exp Med. 1950 Aug;92(2):121-8 15428581 Am J Med. 1962 Sep;33:408-20 13874135 Am J Med. 1957 Oct;23(4):587-95 13469829 Am J Physiol. 1960 Dec;199:1199-204 13787542 Proc Soc Exp Biol Med. 1955 Nov;90(2):542-7 13273509 Acta

Full Text available with Trip Pro

1965 Journal of Clinical Investigation

159. CHEMICAL STUDIES ON INTESTINAL INFANTILISM : I. ENDOGENOUS METABOLISM: KREATININ, KREATIN, URIC ACID. (PubMed)

CHEMICAL STUDIES ON INTESTINAL INFANTILISM : I. ENDOGENOUS METABOLISM: KREATININ, KREATIN, URIC ACID. In my three cases of intestinal infantilism, the kreatinin excretion was more irregular than normally, and the kreatinin coefficient was low. Kreatin was found in the urine on a kreatin-free diet. The sum of kreatinin and kreatin was also irregular. The endogenous uric acid was irregular from day to day. The kreatin excretion is apparently lower on a high fat diet than on a high carbohydrate

Full Text available with Trip Pro

1912 The Journal of experimental medicine

160. Bioassay of aldosterone antagonists in normal human subjects: a relationship between the level of plasma uric acid before treatment and apparent drug responses. (PubMed)

sodium excretion and the sodium : potassium (Na/K) ratio, and decreased potassium excretion, when compared with placebo. The response to the two active drugs did not differ significantly. 3 The urine Na/K ratio, and log10 Na/K, in response to spironolactone correlated negatively with the level of plasma uric acid measured 12 h before treatment. Similar trends were present after SC-23992 and placebo treatments. 4 It is suggested that the correlations between plasma uric acid and apparent drug response (...) Bioassay of aldosterone antagonists in normal human subjects: a relationship between the level of plasma uric acid before treatment and apparent drug responses. The activity of single doses of SC-23992, a new aldosterone antagonist, and spironolactone in reversing the effects of fludrocortisone on urinary electrolyte composition in normal subjects was compared with that of placebo in a double-blind crossover study. 2 SC-23992 (50 mg) and spironolactone (125 mg) each significantly increased

Full Text available with Trip Pro

1975 British journal of clinical pharmacology

To help you find the content you need quickly, you can filter your results via the categories on the right-hand side >>>>