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Urine Uric Acid

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281. Guidelines for Hospital Discharge of the Breastfeeding Term Newborn and Mother: The Going Home Protocol,

have been performed during the hospitalization, preferably at least once every 8–12 hours. In countries such as Japan, where the hospital stay may last up to a week, assessment should continue until breastfeeding is successfully established and then may decrease in frequency. These should include evaluation of posi- tioning, latch, milk transfer, clinical jaundice, stool color and transition, stool and urine output, and nota- tion of uric acid crystals if present. Infant’s weight and percentage (...) not to overload mothers. Speci?c information should be provided in written form to all parents regarding: a. prevention and management of engorgement b. interpretation of infant cues and feeding ‘‘on cue’’ c. indicators of adequate intake (evacuation of all meconium stools, three to four stools per day by Day 4, transitioning to yellow bowel movements by Day 5, at least ?ve to six urinations per day by Day 5, and regaining birth weight by Day 10–14 at the latest) d. signs of excessive jaundice 4,28 (III) e

2014 Academy of Breastfeeding Medicine

282. Medical Management of Kidney Stones

. (Clinical Principle) 4. Clinicians should obtain or review available imaging studies to quantify stone burden. (Clinical Principle) 5. Clinicians should perform additional metabolic testing in high-risk or interested first-time stone formers and recurrent stone formers. (Standard; Evidence Strength: Grade B) 6. Metabolic testing should consist of one or two 24-hour urine collections obtained on a random diet and analyzed at minimum for total volume, pH, calcium, oxalate, uric acid, citrate, sodium (...) . Clinicians should counsel patients with uric acid stones or calcium stones and relatively high urinary uric acid to limit intake of non-dairy animal protein. (Expert Opinion) 13. Clinicians should counsel patients with cystine stones to limit sodium and protein intake. (Expert Opinion) Pharmacologic Therapies 14. Clinicians should offer thiazide diuretics to patients with high or relatively high urine calcium and recurrent calcium stones. (Standard; Evidence Strength Grade B) 15. Clinicians should offer

2014 American Urological Association

283. Dietary and Pharmacologic Management to Prevent Recurrent Nephrolithiasis in Adults

with each other. Clinical outcomes and adverse events were sparsely reported, but they were more common for pharmacologic than nonpharmacologic therapies. Evidence was insufficient to determine the effect of dietary or pharmacologic therapy based on stone composition or blood and urine chemistries. Most studies included only patients with calcium stones, and no trials assessed treatment in patients with uric acid or cystine stones. See the for a summary of the recommendations and clinical considerations (...) targeting stone composition, biochemistry, or both can favorably alter biochemical composition that leads to stone formation. Clinicians often select pharmacologic therapy on the basis of method of action: Thiazide diuretics reduce urinary calcium and are often prescribed for patients with hypercalciuria, citrates bind to calcium and decrease urine acidity, and allopurinol decreases uric acid in urine. Almost all studies analyzed in the evidence review included only patients with calcium stones, which

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2014 American College of Physicians

284. Diagnosis and management of glycogen storage disease type I: a practice guideline of the American College of Medical Genetics and Genomics

to hyperfiltration may occur in adolescents and young adults with GSD I, similar to what is seen in diabetic patients. Severe renal injury with proteinuria, hypertension, and decreased creatinine clearance due to focal segmental glomeru- losclerosis and interstitial fibrosis, ultimately leading to end- stage renal disease, may also be seen in young adults. 62 Patients with persistently elevated blood lactate, serum lipids, and uric acid levels appear more at risk for nephropathy. 58,63 Patients with GSD Ib have (...) , a hyperlipidemia Hypoglycemia is usually less severe, but the patient may have more severe ketosis and absence of hyperlactatemia and hyperuricemia; ? AST , ALT usually higher (may be >500? U/l); cardiac and skeletal muscle involvement with ? CK concentrations in GSD IIIa; normal blood lactate and uric acid GSD IV (branching enzyme deficiency) Hepatomegaly, ? AST and ALT, a prolonged PT and low albumin in advanced stage of disease Lack of hypoglycemia until end-stage liver disease; PT commonly prolonged in GSD

2014 American College of Medical Genetics and Genomics

285. Pheburane (Sodium phenylbutyrate) - urea cycle disorders

Investigations Common Lowered blood concentrations of potassium, albumin, total protein and phosphate. Elevated blood concentrations of alkaline phosphatases, transaminases, bilirubin, uric acid, chloride, phosphate and sodium. Weight gain. * Common: = 1/100 and < 1/10 ** Very common: = 1/10 Unacceptability Bitter Salty Sweet Ammonaps granules Score on VAS (mm) Mean (± SD) HAS - Medical, Economic and Public Health Assessment Division 10/15 08.3 Usage/prescription data In the context of a cohort TUA, 21 (...) than 20 kg, adolescents and adults. The safety and efficacy of doses in excess of 20 g/day have not been established. Therapeutic monitoring: Plasma levels of ammonia, arginine, essential amino acids (especially branched-chain amino acids), carnitine and serum proteins should be maintained within normal limits. Plasma glutamine should be maintained at levels less than 1000 µmol/l. Nutritional management: PHEBURANE must be combined with dietary protein restriction and, in some cases, essential amino

2014 Haute Autorite de sante

286. Guidance for national tuberculosis programmes on the management of tuberculosis in children

/ritonavir MDR-TB multidrug-resistant tuberculosis NNRTI non-nucleoside reverse-transcriptase inhibitor NRTI nucleoside reverse-transcriptase inhibitor NTP national tuberculosis control programme NVP nevirapine PAS p-aminosalicylic acid PI protease inhibitor PLHIV person living with HIV PMTCT prevention of mother-to-child transmission (of HIV) PPD purified protein derivative PTB pulmonary tuberculosisxv Guidance for national tuberculosis programmes on the management of tuberculosis in children R (...) (Strong recommendation, very low quality of evidence) Source: Automated real-time nucleic acid amplification technology for rapid and simultaneous detection of tuberculosis and rifampicin resistance: Xpert MTB/RIF sys- tem for the diagnosis of pulmonary and extrapulmonary TB in adults and children. Policy Update. Geneva, World Health Organization, 2013. n Recommendation 2 (new) Xpert MTB/RIF may be used rather than conventional microscopy and cul- ture as the initial test in all children suspected

2014 World Health Organisation Guidelines

287. Royal Flying Doctor Service Western Operations Clinical manual part 1.Clinical guidelines

1 12.2 Acute Asthma 3 12.3 Bronchiolitis 5 13 TOXICOLOGY 1 13.1 Snakebite 1 13.2 Red-back Spider Bite (RBSB) 4 13.3 Irukandji Syndrome 6 13.4 An Approach To Poisoning 8 13.5 Paraquat Poisoning 9 13.6 Serotonin Syndrome 11 13.7 Cyanide Poisoning 12 14 TRAUMA 1 14.1 Burns 1 14.2 Hydrofluoric Acid Burns 5 14.3 Identification and Management of Pelvic Fractures 6 14.4 Crush Syndrome 8 14.5 Fractured Neck of Femur 9 14.6 Screening Adults With Suspected Cervical Spine Fractures 10 14.7 Acute Spinal (...) Computerised tomography pulmonary angiogram AFB Acid fast bacilli CVA Cerebrovascular accident ALS Advanced life support CVC Central venous catheter APH Antipartum haemorrhage CVP Central venous pressure APO Acute pulmonary oedema CXR Chest x-ray ARCBS Australian Red Cross Blood Service DBP Diastolic blood pressure ARDS Adult respiratory distress syndrome DC Direct current ATLS Advanced trauma life support DIC Disseminated intravascular coagulopathy BBB Bundle branch block DKA Diabetic keto-acidosis BP

2014 Clinical Practice Guidelines Portal

290. European Society of Endocrinology Clinical guideline for the management of hyponatraemia

of water from the primitive urine in the distal tubules of the nephron, which leads to urine that is more concentrated. To prevent persistent thirst, the threshold for releasing vasopressin is lower than that for triggering thirst ( ) . Figure 3 Osmotic stimulation of vasopressin release. Schematic representation of normal physiological relationships among plasma osmolality, plasma AVP concentrations, urine osmolality and urine volume in man. Note particularly the inverse nature of the relationship (...) between urine osmolality and urine volume, resulting in disproportionate effects of small changes in plasma AVP concentrations on urine volume at lower AVP levels. Reproduced with permission from Elsevier Copyright © 2003 Verbalis JG. Disorders of body water homeostasis. Best Practice & Research. Clinical Endocrinology & Metabolism 2003 17 471–503. Citation: European Journal of Endocrinology 170, 3; 5.3.1. Osmoregulation and vasopressin release Under normal circumstances, osmotic regulation

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2014 European Society of Endocrinology

291. Clinical practice guideline for care in pregnancy and puerperium

creatinine level in a biochemical test? 8. What is the purpose of determining the plasma uric acid level in a biochemical test? 9. What is the purpose of universal screening for syphilis in pregnant women and at what stage of pregnancy should it be done? 10. What is the purpose of universal screening for Chagas disease in pregnant women and at what stage of pregnancy should it be done? 11. What is the purpose of universal screening for chlamydia in pregnant women and at what stage of pregnancy should (...) pregnancy? 39. With a varied diet, are micronutrient needs as iron, vitamins or iodine covered? Pharmacological supplementation of nutrients 40. What is the effect of iron prophylaxis in women during pregnancy? 41. Is a pharmacological iodine supplementation necessary during pregnancy? 42. Is a pharmacological folic acid supplementation necessary during pregnancy? 43. Is a pharmacological vitamin complex supplementation necessary during pregnancy? 44. How safe are food supplements (omega3 fatty acids

2014 GuiaSalud

292. Spleen-Kidney Supplementing Formula Alleviates Renal Fibrosis in Diabetic Rats via TGF-<i>β</i>1-miR-21-PTEN Signaling Pathway. (PubMed)

model was induced by high-fat diet and multiple injections of low-dose streptozotocin. After 8-week intervention, samples were collected for detection.SKSF decreased fasting blood glucose, glycosylated hemoglobin A1c, blood urea nitrogen, uric acid, urea, 24-hour urine protein, and KW/BW ratio, while it increased creatinine clearance rate of T2DM rats. Meanwhile, SKSF attenuated the renal fibrosis and improved the morphology and structure of renal tissue. Furthermore, SKSF significantly reduced

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2018 Evidence-based Complementary and Alternative Medicine (eCAM)

293. MKSAP: 53-year-old woman with hypertension and chronic active hepatitis B infection

tubulointerstitial disease. An associated characteristic that may be present with tubulointerstitial disease is abnormal tubular handling of glucose, amino acids, uric acid, phosphate, and bicarbonate (termed Fanconi syndrome ); renal tubular acidosis is also common. Patients may also have concentrating defects and may present with nocturia and polyuria. With more advanced disease, anemia may be present due to the destruction of erythropoietin-producing cells in the kidney. This patient’s findings are consistent (...) disease. This patient has tubulointerstitial disease, likely due to long-standing exposure to tenofovir. Evidence for a tubulointerstitial process includes a slowly progressive course without a clear inciting event, subnephrotic proteinuria, bland urine sediment, and a kidney ultrasound showing atrophic kidneys. History and physical examination should focus on conditions associated with tubulointerstitial disease and a careful review of medications, because numerous medications may induce

2018 KevinMD blog

294. A Fluorescent Biosensors for Detection Vital Body Fluids’ Agents (PubMed)

presents the fluorescent biosensors for the detection of neurotransmitters, hormones, and other human metabolites as glucose, lactate or uric acid. The construction of microfluidic devices based on fluorescence uses a variety of materials, fluorescent dyes, types of detectors, excitation sources, optical filters, and geometrical systems. Due to their small size, these devices can perform a full analysis. Microfluidics-based technologies have shown promising applications in several of the main (...) A Fluorescent Biosensors for Detection Vital Body Fluids’ Agents The clinical applications of sensing tools (i.e., biosensors) for the monitoring of physiologically important analytes are very common. Nowadays, the biosensors are being increasingly used to detect physiologically important analytes in real biological samples (i.e., blood, plasma, urine, and saliva). This review focuses on biosensors that can be applied to continuous, time-resolved measurements with fluorescence. The material

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2018 Sensors (Basel, Switzerland)

295. Biochemical Assessment of Renal and Liver Function among Preeclamptics in Lagos Metropolis (PubMed)

obtained. Venous blood and spot urine samples were collected from each participant. Plasma obtained from blood samples taken into lithium heparinized vacutainer bottles was assayed for electrolytes, urea, creatinine, total protein, albumin, and uric acid, while sera samples from blood samples taken into serum separation tube- (SST-) gel vacutainer were assayed for aspartate transaminase and alanine transaminase using ion selective electrode technique and Cobas autoanalyzer. Spot urine samples were (...) assayed for protein and creatinine using Pyrogallol's reagent and Jaffe's methods, respectively. Microalbuminuria (protein/creatinine ratio) was generated from spot urine protein and creatinine data.The plasma sodium, total protein, and albumin in preeclamptic group were significantly decreased (p<0.05) when compared with control. There was statistically significant increase (p<0.05) in microalbuminuria, plasma potassium, urea, creatinine, uric acid levels, serum AST, and ALT activities

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2018 International journal of reproductive medicine

296. Impact of Dietary Intervention on Tumor Immunity: the DigesT Trial

, cholesterol, amino acids) FMD-induced changes in urine metabolites [ Time Frame: 3 years ] FMD-induced changes in urine metabolites (ketone bodies) FMD-induced changes in serum growth factors. [ Time Frame: 3 years ] FMD-induced changes in serum growth factors. Qualitative changes in tumor-infiltrating immune cells [ Time Frame: 3 years ] Qualitative changes in the type of tumor-infiltrating immune cell populations before and after the diet in breast cancer patients undergoing curative surgery (Cohort (...) blood uric acid < 10 mg/dl ALT and AST ≤ 2.5 x ULN total bilirubin < ULN except for patients with Gilbert syndrome who may only be included in the total bilirubin is < 3.0 x ULN or direct bilirubin < 1.5 x ULN Albumin > 3 g/dL Fasting glucose ≤ 200 mg/dl. Total Cholesterol ≤ 300 mg/dl. Triglycerides ≤ 300 mg/dl. Female patients of childbearing potential must agree to sexual abstinence or to use two highly effective method of contraception throughout the study and for at least 30 days after the end

2018 Clinical Trials

297. A Phase I Study of LuoXin Innovate (LXI-15028) in Healthy Chinese Subjects to Evaluate the Pharmacokinetics, Safety and Tolerability.

phosphatase (ALP), aspartate aminotransferase (AST), alanine aminotransferase (ALT), glutamyltransferase (γ-GT), magnesium, sodium, potassium, chlorine, total calcium, inorganic phosphorus, lactate dehydrogenase (LDH), glucose, uric acid, triglyceride (TG); and list all the result. Adverse events of single dose [ Time Frame: Up to 3 weeks ] The adverse events are encoded using MedDRA 20.1. According to system organ classification (SOC) and preferred term (PT), all TEAE, investigational drug-related TEAE (...) , total bilirubin, Conjugated bilirubin, creatinine, creatine kinase (CPK), alkaline phosphatase (ALP), aspartate aminotransferase (AST), alanine aminotransferase (ALT), glutamyltransferase (γ-GT), magnesium, sodium, potassium, chlorine, total calcium, inorganic phosphorus, lactate dehydrogenase (LDH), glucose, uric acid, triglyceride (TG); and list all the result. Adverse events of multiple doses [ Time Frame: Up to 6 weeks ] The adverse events are encoded using MedDRA 20.1. According to system organ

2018 Clinical Trials

298. A Clinical Study Evaluating the Efficacy and Safety of RPh201 Treatment in Individuals With Alzheimer's Disease With or Without Coexisting Cerebrovascular Disease

] Clinical Laboratory Assessments - (blood and urine) at at Month 6 [ Time Frame: Month 6 ] Chemistry: alkaline phosphatase, albumin, blood urea nitrogen, calcium, chloride, creatinine, glucose (random), inorganic phosphorus, potassium, alanine aminotransferase, aspartate aminotransferase, gamma-glutamyl transpeptidase, lactate dehydrogenase, sodium, direct bilirubin, total bilirubin, total protein, amylase, uric acid Hematology: haemoglobin, hematocrit, red blood cell count, white blood cell (WBC) count (...) dehydrogenase, sodium, direct bilirubin, total bilirubin, total protein, amylase, uric acid Hematology: haemoglobin, hematocrit, red blood cell count, white blood cell (WBC) count, WBC differential (absolute counts), numerical platelet count Urinalysis: specific gravity, pH, ketones, glucose, nitrite, blood, leukocyte esterase, protein, urobilinogen, bilirubin If nitrite, blood, or protein tests are positive, a microscopic examination will be performed Vital Signs [ Time Frame: Month 12 ] Vital signs

2018 Clinical Trials

299. Remaxol® in Malignant Mechanical Jaundice

: treatment Remaxol® 800 ml IV, once a day for 10 days, along with standard infusion therapy. Group III: patients will receive placebo ((Ringer solution) 800 ml IV, once a day for 10 days, along with standard infusion therapy. Assessment will include physical examination data, vital signs, blood tests (CBC, biochemistry - protein, albumin, AST, ALT, APG, GGTP, LDH, total bilirubin, direct bilirubin, amylase, glucose, electrolytes, creatinine, urea, uric acid, C -reactive protein, lipid profile (...) ; coagulogram; urine samples), ECOG assessment, repeated abdominal ultrasound, neurophysiological test for the evaluation of encephalopathy, record of bile volume by drainage (if applicable). All patients will be followed up for 31 days. Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Estimated Enrollment : 288 participants Allocation: Randomized Intervention Model: Parallel Assignment Masking: Triple (Participant, Care Provider, Investigator) Primary

2018 Clinical Trials

300. Peer Support To Enhance The Shanghai Integration Model Of Diabetes Care: Extension & Dissemination

Urea at 6 and 12 months [ Time Frame: Baseline, 6 months, 12 months ] Blood urea (mmol/L) Change from Baseline Serum Creatinine at 6 and 12 months [ Time Frame: Baseline, 6 months, 12 months ] Serum creatinine (µmol/L) Change from Baseline Uric Acid at 6 and 12 months [ Time Frame: Baseline, 6 months, 12 months ] Uric acid (µmol/L) Change from Baseline Urine Albumin/Creatinine Ratio at 6 and 12 months [ Time Frame: Baseline, 6 months, 12 months ] Albumin (mg/L), Creatinine (mmol/L) Change

2018 Clinical Trials

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