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Urine Uric Acid

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181. Effects of Green Tea on Level of Serum Uric Acid in Healthy Individuals

Effects of Green Tea on Level of Serum Uric Acid in Healthy Individuals Effects of Green Tea on Level of Serum Uric Acid in Healthy Individuals - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Effects (...) of Green Tea on Level of Serum Uric Acid in Healthy Individuals The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT01363869 Recruitment Status : Completed First Posted : June 2, 2011 Last Update Posted : April 25, 2013 Sponsor: Chiang Mai University Information provided by (Responsible Party): Kanon

2011 Clinical Trials

182. Uric acid Full Text available with Trip Pro

purified from milk and extracts. Uric acid is released in conditions (low oxygen saturation). Genetic and physiological diversity [ ] Primates . In and , uric acid (actually hydrogen urate ion) is the final (breakdown) product of and is excreted in urine, whereas in most other , the enzyme further oxidizes uric acid to . The loss of uricase in higher primates parallels the similar loss of the ability to synthesize , leading to the suggestion that urate may partially substitute for ascorbate (...) % of humans, impaired renal (kidney) excretion leads to . Normal excretion of uric acid in the urine is 250 to 750 mg per day (concentration of 250 to 750 mg/L if one litre of urine is produced per day — higher than the solubility of uric acid because it is in the form of dissolved acid urates). Dogs . The has a genetic defect in uric acid uptake by the and , resulting in decreased conversion to allantoin, so this breed excretes uric acid, and not allantoin, in the urine. Birds and reptiles

2012 Wikipedia

183. The BANGALORE Study; Combination of Berberine, Lipoic Acid, and Picrorhiza

in: Endothelial function using noninvasive brachial artery reactivity (BAR) ultrasound Biomarkers including IL-6, HOMA-IR, HbA1C, hsCRP, adiponectin, plasma/urine isoprostanes, PAI-1, TNFα-II, aldosterone, and glutathione redox ratio Urinary protein excretion Clinical chemistry including plasma glucose, blood urea nitrogen, creatinine, total bilirubin, uric acid, transaminases (SGOT/AST, SGPT/ALT), alkaline phosphatase, C-reactive protein, and lipoproteins Condition or disease Intervention/treatment Phase (...) , and glutathione redox ratio Urinary protein excretion Clinical chemistry including plasma glucose, blood urea nitrogen, creatinine, total bilirubin, uric acid, transaminases (SGOT/AST, SGPT/ALT), alkaline phosphatase, C-reactive protein, and lipoproteins Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Actual Enrollment : 28 participants Allocation: Randomized Intervention Model: Parallel Assignment Masking: Quadruple (Participant, Care Provider, Investigator

2012 Clinical Trials

184. Evaluation of Intravenous Ascorbic Acid

: Healthy adults age 21 or older Laboratory: ANC ≥1,500/mm3, Hemoglobin > 8g/dL, platelet ≥ 100,000/mm3, total bilirubin ≤ 1.5 mg/dL, creatinine ≤2.0 mg/dL, transaminase (AST/ALT) ≤2.5X upper limit, urine uric acid < 1,000mg/d, urine pH <6, urine oxalate <60 mg/d. Participants who have no language barrier, are cooperative, and can give informed consent before entering the study after being informed of the medications and procedures to be used in this study may participate. Exclusion: Glucose-6-phosphate (...) limit, urine uric acid < 1,000mg/d, urine pH <6, urine oxalate <60 mg/d. Participants who have no language barrier, are cooperative, and can give informed consent before entering the study after being informed of the medications and procedures to be used in this study may participate. Exclusion: Glucose-6-phosphate-dehydrogenase (G6PD) deficiency Currently receiving chemotherapy or radiation therapy History of bleeding disorder History of oxalate renal calculi; urine oxalate level > 60 mg/d

2012 Clinical Trials

185. Organic acid excretion patterns in gout. Full Text available with Trip Pro

Organic acid excretion patterns in gout. 5016863 1972 06 15 2018 11 13 0003-4967 31 2 1972 Mar Annals of the rheumatic diseases Ann. Rheum. Dis. Organic acid excretion patterns in gout. 137-44 Kramer H J HJ Lu E E Gonick H C HC eng Journal Article England Ann Rheum Dis 0372355 0003-4967 0 Acids 0 Citrates 0 Fumarates 0 Ketoglutaric Acids 0 Lactates 0 Malates 0 Oxalates 0 Pyruvates 0 Succinates 0 Tricarboxylic Acids 142M471B3J Carbon Dioxide 268B43MJ25 Uric Acid IM Acids urine Adult Aged Carbon (...) Dioxide blood Chromatography, Gas Citrates urine Citric Acid Cycle Fumarates urine Glomerular Filtration Rate Gout urine Humans Hydrogen-Ion Concentration Ketoglutaric Acids urine Lactates urine Malates urine Male Middle Aged Osmolar Concentration Oxalates urine Pyruvates urine Succinates urine Tricarboxylic Acids urine Uric Acid blood metabolism urine 1972 3 1 1972 3 1 0 1 1972 3 1 0 0 ppublish 5016863 PMC1005883 Metabolism. 1960 Jan;9:52-8 13815869 Proc R Soc Med. 1966 Apr;59(4):292-302 5327976 Anal

1972 Annals of the Rheumatic Diseases

186. Nitrogen Sparing Induced by a Mixture of Essential Amino Acids Given Chiefly as Their Keto-Analogues during Prolonged Starvation in Obese Subjects Full Text available with Trip Pro

/day on the last day of infusions; 5 days later it was still lower (0.63 g/day) and in two subjects studied for 9 and 17 days postinfusion it remained below preinfusion control values. Urine ammonia, creatinine, and uric acid were unaltered. Nitrogen balance became less negative during and after infusions. The results indicate that this mixture of essential amino acids and their keto-analogues facilitates nitrogen sparing during prolonged starvation, in part by conversion of the ketoacids to amino (...) Nitrogen Sparing Induced by a Mixture of Essential Amino Acids Given Chiefly as Their Keto-Analogues during Prolonged Starvation in Obese Subjects 11 normal obese subjects were fasted for 33 days. In five, who served as controls, urine urea nitrogen excretion remained constant for 2 wk thereafter. The other six were given seven daily infusions containing 6-8 mmol each of the alpha-keto-analogues of valine, leucine, isoleucine, phenylalanine, and methionine (as sodium salts) plus 3-4 mmol each

1974 Journal of Clinical Investigation

187. Uricosuric agents in uremic sera. Identification of indoxyl sulfata and hippuric acid. Full Text available with Trip Pro

Uricosuric agents in uremic sera. Identification of indoxyl sulfata and hippuric acid. Serum and urine from chronically uremic patients and normal individuals were subjected to gel filtration of Sephadex-G10. The effects of the eluted fractions on the uptake of urate and para-aminohippurate by isolated cortical tubules of rabbit kidney were investigated. According to the origin of the samples, one to three major groups of fractions inhibiting both urate and para-aminohippurate transport were (...) disclosed. The first eluted group occurred for all the samples under study. The second one was demonstrated in both sera and urines from uremic patients but only in urines from normal individuals. The third one was exclusively detected in uremic sera and urines. Among all the compounds identified, only hippuric acid, eluted in the fractions of the second group, was capable of inhibiting the uptake of urate and para-aminohippurate in vitro. The concentration for which this inhbiitory effect of hippuric

1975 Journal of Clinical Investigation

188. The elimination of salicylic acid in man: serum concentrations and urinary excretion rates. Full Text available with Trip Pro

blood metabolism urine Uric Acid physiology 1966 2 1 1966 2 1 0 1 1966 2 1 0 0 ppublish 5912691 PMC1510654 J Pharm Sci. 1965 Jul;54(7):959-67 5862532 Nature. 1966 Feb 5;209(5023):620-1 5921196 J Pharmacol Exp Ther. 1957 Aug;120(4):528-39 13476377 Br Med J. 1964 Aug 1;2(5404):286-8 14160212 Biochem Pharmacol. 1964 May;13:767-76 14181279 Nature. 1964 May 23;202:779-80 14187617 Br Med J. 1964 Oct 24;2(5416):1033-6 14191162 Br J Pharmacol Chemother. 1965 Apr;24:418-31 14320855 J Am Pharm Assoc Am Pharm (...) The elimination of salicylic acid in man: serum concentrations and urinary excretion rates. 5912691 1966 11 28 2018 11 13 0366-0826 26 2 1966 Feb British journal of pharmacology and chemotherapy Br J Pharmacol Chemother The elimination of salicylic acid in man: serum concentrations and urinary excretion rates. 461-7 Cummings A J AJ Martin B K BK Renton R R eng Journal Article England Br J Pharmacol Chemother 0154627 0366-0826 0 Salicylates 268B43MJ25 Uric Acid IM Adult Humans Male Salicylates

1966 British journal of pharmacology and chemotherapy

189. Tienilic acid: pharmacokinetics, salicylate interaction and creatinine secretion studies. (Abstract)

metabolites. A 650 mg dose of acetylsalicylic acid significantly decreased the uricosuric effect of tienilic acid by inhibiting uric acid secretion. Urine pH fell significantly with tienilic acid administration. Tienilic acid inhibited salicylate excretion by either competition for tubular secretion or by increasing passive, pH dependent reabsorption. In normal subjects given a creatinine load, tienilic acid did not inhibit creatinine secretion. (...) Tienilic acid: pharmacokinetics, salicylate interaction and creatinine secretion studies. Tienilic acid is a diuretic-uricosuric compound whose natriuretic site of action is in the cortical diluting segment of the distal nephron. Oral doses of 250 mg given to normal human volunteers provided peak blood levels of 10--11 micrograms/ml at 3--4 hours after administration. Approximately 40% of the dose was recovered in 24 hours, 30% as the parent compound and 10% as the alcohol and diacid

1979 Postgraduate medical journal Controlled trial quality: uncertain

190. Idiopathic recurrent calcium urolithiasis (IRCU): pathophysiology evaluated in light of oxidative metabolism, without and with variation of several biomarkers in fasting urine and plasma - a comparison of stone-free and -bearing male patients, emphasizing Full Text available with Trip Pro

of markers.1) In SB vs. SF unstratified OM biomarkers were statistically unchanged, but the majority of patients was overweight; despite, in SB vs. SF urine pH, total and non-albumin protein concentration were elevated, fractional urinary uric acid excretion and blood bicarbonate decreased, whereas urine volume, sodium, supersaturation with CaOx and CaPi (as hydroxyapatite) were unchanged; 2) upon variation of OM markers (strata below and above median) numerous stone parameters differed significantly (...) , among others urine volume, total protein, Ca/Pi ratio, pH, sodium, potassium, plasma Ca/Pi ratio and parathyroid hormone, blood pressure, renal excretion of non-albumin protein and other substances; 3) a significant shift from SF to SB patients occurred with increase of urine pH, decrease of blood bicarbonate, and increase of diastolic blood pressure, whereas increase of plasma uric acid impacted only marginally; 4) in both SF and SB patients a strong curvilinear relationship links a rise of urine

2011 European Journal Of Medical Research

191. Beware the low urine ph - the major cause of the increased prevalence of nephrolithiasis in the patient with type 2 diabetes. (Abstract)

Beware the low urine ph - the major cause of the increased prevalence of nephrolithiasis in the patient with type 2 diabetes. There is an increased prevalence of nephrolithiasis and an increase in the incidence of renal colic in patients with diabetes, obesity, hypertension and insulin resistance because of an increased frequency of uric acid crystallization. Uric acid crystallization occurs in the milieu of an acid urine and is not due to hyperuricosuria as with insulin resistance, urinary (...) uric acid levels are generally decreased because of increased renal tubular reabsorption. However, in the presence of insulin resistance, there is decreased renal tubular generation of ammonia and increased sodium absorption leading to acidification of the urine and uric acid crystallization. The presence of a low urine pH should alert the clinician to the increased risk of nephrolithiasis particularly in the obese, diabetic or hypertensive patient. Prevention of nephrolithiasis can be achieved

2011 obesity & metabolism

192. Metabolic Syndrome, Urine pH, and Time-dependent Risk of Nephrolithiasis in Korean Men Without Hypertension and Diabetes. (Abstract)

(US). A standard Cox proportional hazards model and a time-dependent Cox model were used to calculate the adjusted hazard ratio in the NL model.After adjusting for age, baseline glomerular filtration rate, and uric acid level, MS at baseline was associated with a significantly increased risk of NL (HR, 1.771; 95% confidence interval, 1.157-2.711). MS over time as a time-dependent variable also predicted the development of NL (HR, 1.678; 95% CI, 1.151-2.447) after adjusted baseline covariate. After (...) Metabolic Syndrome, Urine pH, and Time-dependent Risk of Nephrolithiasis in Korean Men Without Hypertension and Diabetes. To examine the independent effect of metabolic syndrome (MS) on nephrolithiasis (NL) even with changes in MS status over time.From 2002-2003, 3872 men who were reexamined annually or biannually until 2009 were enrolled in the analysis and observed for development of NL. The examination included anthropometric measurements, biochemical measurement, and kidney ultrasonography

2011 Urology

193. Urination

and reptiles is whitish, consisting of a pastelike suspension of uric acid crystals, and discharged with the of the animal via the , whereas mammals' urine is a yellowish colour, with mostly instead of uric acid, and is discharged via the urethra, separately from the . Some animals' (example: ') urine possesses a strong odour, especially when it is used to mark territory or communicate in other ways. [ ] Stallions sometimes exhibit the by smelling the urine of a mare in heat. A stallion sometimes his (...) Urination Urination - Wikipedia Urination From Wikipedia, the free encyclopedia release of urine from the urinary bladder "Tinkling" redirects here. For a dictionary definition, see . For the Filipino dance, see . "Voiding" redirects here. For other uses, see . depicts a urinating boy. Urination is the release of from the through the to the outside of the body. It is the 's form of . It is also known medically as micturition , voiding , uresis , or, rarely, emiction , and known colloquially

2012 Wikipedia

196. KDOQI Clinical Practice Guidelines for Nutrition in CKD

- Oral, Enteral, and Parental Nutrition ……………………… ……………………………….. 103 4.2 Nutrition Supplementation - Dialysate………………………………………..…….…… 115 4.3 Long Chain Omega-3 Polyunsaturated Fatty Acids ………………………… 119 Guideline 5: Micronutrients.……………………………………………………….…………. 128 5.0 General Guidance ……………………………………………………………………….. 128 5.1 Folic acid (with and without other B Vitamins) ……..…………………………………… 132 5.2 Vitamin C ………………………………………………………………………………… 137 5.3 Vitamin D ………………………………………………………………………………… 142 5.4 Vitamin E (...) and A ……………………………………………..…………………………… 148 5.5 Vitamin K ………………………………………………………………………………… 155 5.6 Selenium and Zinc………………………………………………………………………………….. 159 Guideline 6: Electrolytes.………………………………………………………………………….……. 164 6.1 Acid-Base ………………………………………………………………………………… 164 6.2 Calcium ………………………………………………………………..…………………… 171 6.3 Phosphorus …………………………………………………………...…………………… 175 6.4 Potassium ……………………………………………………………….………………… 184 6.5 Sodium …………………………………………………………….……………………… 188 Biographic and Disclosure Information…………………………………………………………………. 196

2020 National Kidney Foundation

197. Prenatal Care

include a complete blood count with platelets, AST, ALT, and serum creatinine. Serum uric acid has a low positive predictive value and is generally not helpful. The complete management of hypertension in pregnancy is beyond the scope of this guideline. For detailed recommendations regarding the care of these patients, the use of another resource is recommended. The following principles may aid in the care of these patients. Patients at high risk for development of preeclampsia include patients (...) /creatinine ratio on a random specimen or a timed urine collection, is preferred. Significant proteinuria may also be documented at a level of = 1+ protein on dipstick, but due to variability in this test, confirmation is suggested using one of the previously mentioned techniques. If the protein/creatinine ratio is normal and clinical suspicion is high, consider repeating the test or performing a timed urine collection. Additional laboratory tests that may aid in the evaluation of suspected preeclampsia

2020 University of Michigan Health System

198. Tumour lysis syndrome

tetany Trousseau sign Chvostek sign peripheral oedema haematological malignancy large tumour burden chemosensitive tumours recent chemotherapy renal impairment dehydration advanced age nephrotoxic medication Diagnostic investigations serum uric acid serum phosphate serum potassium serum calcium full blood count lactate dehydrogenase serum creatinine serum urea urine pH ECG Treatment algorithm INITIAL ACUTE Contributors Authors Clinical Professor of Medicine University of Colorado Denver CO

2018 BMJ Best Practice

199. Gestational hypertension

being small for gestational age type 1 diabetes mellitus migraine Diagnostic investigations urinalysis FBC LFTs electrolytes, urea, creatinine uric acid 24-hour BP monitoring fetal ultrasound proteinuria (24-hour urine collection) Treatment algorithm ACUTE Contributors Authors Board-certified, General Preventive Medicine & Public Health Preventive Medicine Consultants, PLLC Scottsdale AZ Disclosures AS declares that she has no competing interests. Peer reviewers Associate Professor of Medicine

2018 BMJ Best Practice

200. Syndrome of inappropriate antidiuretic hormone

headache seizure coma no hx of recent diuretic use age >50 years pulmonary conditions (e.g., pneumonia) nursing home residence postoperative state malignancy medicine associated with SIADH induction central nervous system (CNS) disorder endurance exercise Diagnostic investigations serum sodium serum osmolality serum urea urine osmolality urine sodium diagnostic trial with normal saline infusion serum uric acid fractional excretion of sodium fractional excretion of urea serum TSH serum cortisol level (...) with the antidiuretic hormone AVP for binding at the vasopressin receptor, permitting free water excretion. Definition The syndrome of inappropriate antidiuretic hormone (SIADH) is characterised by hypotonic hyponatraemia, concentrated urine, and a euvolaemic state. The impairment of free water excretion is caused by increased arginine vasopressin (antidiuretic hormone or AVP) release. Pseudohyponatraemia due to hyperglycaemia, hyperlipidaemia, or hyperproteinaemia should be ruled out first. Renal failure, adrenal

2018 BMJ Best Practice

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