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Urine Appearance

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1. Urine Appearance

Urine Appearance Urine Appearance Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Urine Appearance Urine Appearance Aka: Urine (...) Appearance , Urine Color , Urine Discoloration , Chromaturia , Dark Urine , Black Urine , Green Urine , Brown Urine II. Signs: Cloudy urine causes Urine with high phosphate, oxalate, lipids, Urine WBCs High purine food intake (increased ) III. Signs: Brown Urine causes Bile pigment Fava beans Medications ( , , ) IV. Signs: Black Urine (or dark or purple) causes Methemoglobinuria or senna Methydopa (PUBS) V. Signs: Blue or Green Urine due to Pseudomonas Bilverdin Medications , Intravenous mendications

2018 FP Notebook

2. U-Drain for people needing night drainage of urine or dialysis fluid

U-Drain for people needing night drainage of urine or dialysis fluid U-Dr U-Drain for people needing night dr ain for people needing night drainage of ainage of urine or dialysis fluid urine or dialysis fluid Medtech innovation briefing Published: 9 February 2017 nice.org.uk/guidance/mib95 pathways Summary Summary The technology technology described in this briefing is the U-Drain. It is used for people with a long-term urinary catheter, urinary sheath, urostomy pouch or who have automated (...) peritoneal dialysis, who need night drainage of urine or dialysis fluid. The inno innovativ vative aspects e aspects are that it is a drainage system that is permanently installed in the user's home. It is used overnight for draining waste fluid directly into the existing soil pipe. The intended place in ther place in therap apy y would be as an alternative to overnight drainage of urine or waste fluid into a night drainage bag in people with long-term urinary catheters, urinary sheaths, urostomy pouches

2017 National Institute for Health and Clinical Excellence - Advice

3. Prescribing anti-inflammatories for urine infection reduces antibiotic use but increases complication risk

) with symptoms and urine dipstick positive for white blood cells and/or nitrites. Pregnant women and those with possible kidney infection were excluded, as were women with various other medical conditions. Women were given the antibiotic norfloxacin (400mg daily) or the NSAID diclofenac (75mg daily) for three days. Both drugs had the same appearance and dosing frequency, so neither women nor doctors knew which treatment was given. A “rescue” antibiotic (fosfomycin) was available to all women if symptoms (...) Prescribing anti-inflammatories for urine infection reduces antibiotic use but increases complication risk Anti-inflammatories for urine infection reduces antibiotic use but increases complication risk Discover Portal Discover Portal Prescribing anti-inflammatories for urine infection reduces antibiotic use but increases complication risk Published on 5 June 2018 doi: Urinary tract infection symptoms resolved by three days for 80% of women given antibiotics compared with 54% given anti

2019 NIHR Dissemination Centre

4. Clinical Policy for Well-Appearing Infants and Children Younger Than 2 Years of Age Presenting to the Emergency Department With Fever

shown to effectively exclude urinary tract infection. Physicians should consider urinalysis and urine culture testing to identify urinary tract infection in well-appearing infants and children aged 2 months to 2 years with a fever ≥38°C (100.4°F), especially among those at higher risk for urinary tract infection. Level A Recommendations None specified. Level B Recommendations None specified. Level C Recommendations Infants and children at increased risk for urinary tract infection include females (...) younger than 12 months, uncircumcised males, nonblack race, fever duration greater than 24 hours, higher fever (≥39°C), negative test result for respiratory pathogens, and no obvious source of infection. Although the presence of a viral infection decreases the risk, no clinical feature has been shown to effectively exclude urinary tract infection. Physicians should consider urinalysis and urine culture testing to identify urinary tract infection in well-appearing infants and children aged 2 months

2016 American College of Emergency Physicians

5. The influence of juicing on the appearance of blueberry metabolites 2 h after consumption: a metabolite profiling approach. Full Text available with Trip Pro

of juicing on the relative appearance of blueberry metabolites in humans using metabolomics. Nine healthy subjects consumed 250 g of fresh blueberries either as the whole fruit or after juicing, and provided blood and urine samples before and 2 h after intake in a cross-over design. Samples underwent metabolite profiling using LCMS, and data were mined with multivariate analysis. Overall, <12 % of all ions detected were significantly influenced by blueberry treatment (P<0·05). Partial least-squared (...) The influence of juicing on the appearance of blueberry metabolites 2 h after consumption: a metabolite profiling approach. The consumption of berries has been linked to decreased risk of degenerative disease. Berries are regularly processed into juices. It is largely unknown how the juicing process affects the bioavailability of metabolites. As metabolomics has shown to be a valuable nutritional tool to study global metabolite differences, the aim of this study was to investigate the effect

2019 The British journal of nutrition Controlled trial quality: uncertain

6. FGF21 increases water intake, urine output and blood pressure in rats. Full Text available with Trip Pro

, which was accompanied by an elevation in urine output that appeared prior to a significant change in water intake. We observed that FGF21 rapidly and significantly increased heart rate and blood pressure in telemeter-implanted rats, before changes in urine output and water intake were observed. Our data suggest that sympathetic activation may contribute to the pathogenesis by which FGF21 increases blood pressure as the baroreceptor unloading induced reflex tachycardia was significantly elevated (...) FGF21 increases water intake, urine output and blood pressure in rats. Fibroblast growth factor 21 (FGF21) is a hormone secreted by the liver in response to metabolic stress. In addition to its well-characterized effects on energy homeostasis, FGF21 has been shown to increase water intake in animals. In this study, we sought to further explore the effects of FGF21 on fluid homeostasis in rats. A single dose of a long-acting FGF21 analog, PF-05231023, significantly increased water consumption

2018 PLoS ONE

7. Changing to a vegetarian diet reduces the body creatine pool in omnivorous women, but appears not to affect carnitine and carnosine homeostasis: a randomised trial. Full Text available with Trip Pro

Changing to a vegetarian diet reduces the body creatine pool in omnivorous women, but appears not to affect carnitine and carnosine homeostasis: a randomised trial. Balanced vegetarian diets are popular, although they are nearly absent in creatine and carnosine and contain considerably less carnitine than non-vegetarian diets. Few longitudinal intervention studies investigating the effect of a vegetarian diet on the availability of these compounds currently exist. We aimed to investigate (...) (3M) and 6 months (6M), a fasted venous blood sample and 24-h urine was collected, and muscle carnosine content was determined by proton magnetic resonance spectroscopy (1H-MRS). Muscle biopsies were obtained at 0M and 3M. Plasma creatine and muscle total creatine content declined from 0M to 3M in Veg+Pla (P=0·013 and P=0·009, respectively), whereas plasma creatine increased from 0M in Veg+Suppl (P=0·004). None of the carnitine-related compounds in plasma or muscle showed a significant time×group

2018 The British journal of nutrition Controlled trial quality: uncertain

8. Appearance and potential predictors of poorly controlled hypertension at the primary care level in an urban community Full Text available with Trip Pro

Appearance and potential predictors of poorly controlled hypertension at the primary care level in an urban community Hypertension (HT) is the major risk factor for cardiovascular diseases because of its poor control. To control HT at the primary care level in urban communities, there is a demand for deeper comprehension of the manifestations of poorly controlled HT. This study aimed to examine appearance of HT, including the association between the appearance and home blood pressure (HBP (...) ) control at the primary care level in urban communities.A cross-sectional study was conducted in July-October 2017 in an urban community in Thailand. The total sample size from randomization was 125 poorly controlled HT patients who were diagnosed with an average clinic blood pressure ≥140/90 mmHg in their last three visits. Data were collected by face-to-face interviews, HBP monitoring (HBPM), and blood and urine testing. Data analysis was conducted via descriptive statistics and the chi-square tests

2018 Journal of multidisciplinary healthcare

9. Peritoneal metastases invading the seminal vesicles: Radiologic appearance and outcome of treatment. (Abstract)

Peritoneal metastases invading the seminal vesicles: Radiologic appearance and outcome of treatment. Cytoreductive surgery (CRS) combined with hyperthermic intraperitoneal chemotherapy (HIPEC) may be of greatest benefit if all visible evidence of disease is resected. In some male patients the peritoneal metastases within the pelvis are invasive into the seminal vesicles and complete cytoreduction requires resection of these structures.From a prospective database of colorectal and appendiceal (...) normal micturition.Resection of the seminal vesicles in a patient with invasion of these structures by peritoneal metastases is possible and should be considered in selected patients. This resection causes impotence but normal urination is to be expected.Copyright © 2018 Elsevier Ltd, BASO ~ The Association for Cancer Surgery, and the European Society of Surgical Oncology. All rights reserved.

2018 European Journal of Surgical Oncology

10. A Study to Evaluate Subject Satisfaction With Facial Appearance Overall and the Aesthetic and Psychosocial Impact of Combined Facial Treatment

A Study to Evaluate Subject Satisfaction With Facial Appearance Overall and the Aesthetic and Psychosocial Impact of Combined Facial Treatment A Study to Evaluate Subject Satisfaction With Facial Appearance Overall and the Aesthetic and Psychosocial Impact of Combined Facial Treatment - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save (...) this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. A Study to Evaluate Subject Satisfaction With Facial Appearance Overall and the Aesthetic and Psychosocial Impact of Combined Facial Treatment The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your

2018 Clinical Trials

11. Urine citrate excretion as a marker of acid retention in patients with chronic kidney disease without overt metabolic acidosis. (Abstract)

Urine citrate excretion as a marker of acid retention in patients with chronic kidney disease without overt metabolic acidosis. Acid (H+) retention appears to contribute to progressive decline in glomerular filtration rate (GFR) in patients with chronic kidney disease (CKD), including some patients without metabolic acidosis. Identification of patients with H+ retention but without metabolic acidosis could facilitate targeted alkali therapy; however, current methods to assess H+ retention (...) are invasive and have little clinical utility. We tested the hypothesis that urine excretion of the pH-sensitive metabolite citrate can identify H+ retention in patients with reduced GFR but without overt metabolic acidosis. H+ retention was assessed based on the difference between observed and expected plasma total CO2 after an oral sodium bicarbonate load. The association between H+ retention and urine citrate excretion was evaluated in albuminuric CKD patients with eGFR 60-89 ml/min/1.73m2 (CKD 2, n=40

2019 Kidney International

12. Urine Podoplanin Heralds the Onset of Ischemia-Reperfusion Injury of the Kidney. (Abstract)

Urine Podoplanin Heralds the Onset of Ischemia-Reperfusion Injury of the Kidney. Ischemia-reperfusion injury represents one of the most common causes of acute kidney injury, a serious and often deadly condition that affects up to 20% of all hospitalized patients in the United States. However, the current standard assay used universally for the diagnosis of acute kidney injury-serum creatinine-does not detect renal damage early in its course. Serendipitously, we found that the immunofluorescent (...) signal of the constitutive podocyte marker podoplanin fades in the glomerulus and intensifies in the tubulointerstitial compartment of the kidney, shortly following ischemia-reperfusion injury in 8-10 week-old male C57Bl/6j mice. Therefore, we sought to define the appearance and course of the podoplanin+ signal in the kidney following ischemia-reperfusion injury. The tubulointerstitial podoplanin+ signal increases as early as 2 hours but persists for 7 days after ischemia-reperfusion injury

2019 American Journal of Physiology. Renal physiology

13. Comparison of urine and blood NGAL for early prediction of delayed graft function in adult kidney transplant recipients: a meta-analysis of observational studies. Full Text available with Trip Pro

Comparison of urine and blood NGAL for early prediction of delayed graft function in adult kidney transplant recipients: a meta-analysis of observational studies. Neutrophil gelatinase-assoicated lipocalin (NGAL) appears to be a promising proximal tubular injury biomarker for early prediction of delayed graft function (DGF) in kidney transplant recipients. However, its predictive values in urine and blood were varied among different studies. Here, we performed the meta-analysis to compare (...) the predictive values of urine NGAL (uNGAL) and blood NGAL (bNGAL) for DGF in adult kidney transplant recipients.We systematically searched Medline, Cochrane library and Embase for relevant studies from inception to May 2018. The summary receiver operating characteristic (SROC) curves, the pooled sensitivity, specificity and diagnostic odds ratio (DOR) were used to evaluate the prognostic performance of uNGAL and bNGAL for the identification of DGF.A total of 1036 patients from 14 eligible studies were

2019 BMC Nephrology

14. Formulas to Estimate Dietary Sodium Intake From Spot Urine Alter Sodium-Mortality Relationship. Full Text available with Trip Pro

Formulas to Estimate Dietary Sodium Intake From Spot Urine Alter Sodium-Mortality Relationship. To study the effect of formulas on the estimation of dietary sodium intake (sodium intake) and its association with mortality, we analyzed the TOHP (Trials of Hypertension Prevention) follow-up data. Sodium intake was assessed by measured 24-hour urinary sodium excretion and estimations from sodium concentration using the Kawasaki, Tanaka, and INTERSALT (International Cooperative Study on Salt, Other (...) was 3766±1290 mg/d. All estimated values, including those with constant sodium concentration, were systematically biased with overestimation at lower levels and underestimation at higher levels. There was a significant linear association between the average measured sodium intake (ie, gold standard method) and mortality. This relationship was altered by using the estimated sodium intakes. There appeared to be a J- or U-shaped relationship for the average estimated sodium by all formulas. Despite

2019 Hypertension

15. Assessment of lactase activity in humans by measurement of galactitol and galactonate in serum and urine after milk intake. Full Text available with Trip Pro

(accuracy 0.92), galactitol and galactonate being more discriminative than galactose.Postprandial galactitol and galactonate after lactose overload appear to be good proxies for genetically determined lactase activity. The development of a noninvasive lactose digestion test based on the measurement of these metabolites in urine could be clinically useful. This trial was registered at clinicaltrials.gov as NCT02230345. (...) Assessment of lactase activity in humans by measurement of galactitol and galactonate in serum and urine after milk intake. Lactase is an enzyme that hydrolyzes lactose into glucose and galactose in the small intestine, where they are absorbed. Hypolactasia is a common condition, primarily caused by genetic programming, that leads to lactose maldigestion and, in certain cases, lactose intolerance. Galactitol and galactonate are 2 products of hepatic galactose metabolism that are candidate

2019 American Journal of Clinical Nutrition

16. A systematic review of the clinical significance of nephrostomy urine cultures. (Abstract)

to infection or pyelonephritis.From 94 studies initially identified, we finally selected two randomised clinical trials (RCT), six original articles and five detailed conference abstracts for the review. These studies suggest that PCN urine cultures are overall useful in clinical practice. They are useful in selecting appropriate antimicrobial treatment for urosepsis following upper urinary obstruction. There does not appear to be any advantage in performing PCN cultures at routine nephrostomy exchanges (...) A systematic review of the clinical significance of nephrostomy urine cultures. There are few published reviews that have assessed the clinical utility of renal urine cultures following percutaneous nephrostomy (PCN). In this systematic review, we evaluated the published evidence of the clinical utility of nephrostomy urine cultures in the light of emerging antimicrobial resistance and need for stewardship.We performed a systematic literature search and review for evidence on the utility

2019 World journal of urology

17. Comparison of urine dipstick and albumin:creatinine ratio for chronic kidney disease screening: A population-based study. Full Text available with Trip Pro

were lower, and non-fatal disease burdens of CKD were larger, in models predicting EQ-5D index using ACR-based categories compared to those using dipstick-based categories, even after adjusting for confounders. In conclusion, the urine dipstick test had poor sensitivity and high false-discovery rates for ACR ≥30 mg/g detection, and classified a large number of individuals into different CKD risk categories compared with ACR-based categories. Therefore, ACR assessments in CKD screening appear (...) Comparison of urine dipstick and albumin:creatinine ratio for chronic kidney disease screening: A population-based study. Chronic kidney disease (CKD) is usually diagnosed using the estimated glomerular filtration rate (eGFR) or kidney damage markers. The urine dipstick test is a widely used screening tool for albuminuria, a CKD marker. Although the urine albumin:creatinine ratio (ACR) has advantages over the dipstick test in sensitivity and quantification of levels, the two methods have

2017 PLoS ONE

18. Urine Sediment Examination in the Diagnosis and Management of Kidney Disease: Core Curriculum 2019. Full Text available with Trip Pro

Urine Sediment Examination in the Diagnosis and Management of Kidney Disease: Core Curriculum 2019. Automated urine technology and centralized laboratory testing are becoming the standard for providing urinalysis data to clinicians, including nephrologists. This trend has had the unintended consequence of making examination of urine sediment by nephrologists a relatively rare event. In addition, the nephrology community appears to have lost interest in and forgotten the utility of provider (...) -performed urine microscopy. However, it is critical to remember that urine sediment examination remains a time-honored test that provides a wealth of information about the patient's underlying kidney disease. This test performs very favorably as a urinary "biomarker" for a number of acute kidney diseases. When used properly, urine sediment findings alert health care providers to the presence of kidney disease, while also providing diagnostic information that often identifies the compartment of kidney

2018 American Journal of Kidney Diseases

19. Night Shift Work Affects Urine Metabolite Profiles of Nurses with Early Chronotype Full Text available with Trip Pro

Night Shift Work Affects Urine Metabolite Profiles of Nurses with Early Chronotype Night shift work can have a serious impact on health. Here, we assess whether and how night shift work influences the metabolite profiles, specifically with respect to different chronotype classes. We have recruited 100 women including 68 nurses working both, day shift and night shifts for up to 5 consecutive days and collected 3640 spontaneous urine samples. About 424 waking-up urine samples were measured using (...) a targeted metabolomics approach. To account for urine dilution, we applied three methods to normalize the metabolite values: creatinine-, osmolality- and regression-based normalization. Based on linear mixed effect models, we found 31 metabolites significantly (false discovery rate <0.05) affected in nurses working in night shifts. One metabolite, acylcarnitine C10:2, was consistently identified with all three normalization methods. We further observed 11 and 4 metabolites significantly associated

2018 Metabolites

20. Evaluation of a New Survivin ELISA and UBC® Rapid for the Detection of Bladder Cancer in Urine Full Text available with Trip Pro

Evaluation of a New Survivin ELISA and UBC® Rapid for the Detection of Bladder Cancer in Urine Urine-based biomarkers for non-invasive diagnosis of bladder cancer are urgently needed. No single marker with sufficient sensitivity and specificity has been described so far. Thus, a combination of markers appears to be a promising approach. The aim of this case-control study was to evaluate the performance of an in-house developed enzyme-linked immunosorbent assay (ELISA) for survivin, the UBC® (...) Rapid test, and the combination of both assays. A total of 290 patients were recruited. Due to prior bladder cancer, 46 patients were excluded. Urine samples were available from 111 patients with bladder cancer and 133 clinical controls without urologic diseases. Antibodies generated from recombinant survivin were utilized to develop a sandwich ELISA. The ELISA and the UBC®Rapid test were applied to all urine samples. Receiver operating characteristic (ROC) analysis was used to evaluate marker

2018 International journal of molecular sciences

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