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Umbilical Cord Blood Gas Analysis

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1. Examination of the Relationship between Umbilical Cord Blood Gas Values and Hearing Function in Neonates (PubMed)

Examination of the Relationship between Umbilical Cord Blood Gas Values and Hearing Function in Neonates The aim of the present study was to examine the relationship between the results of the transient otoacoustic emission (TEOAE) test used in neonatal hearing screening and the results of the umbilical cord blood (UCB) analysis in neonates.This retrospective study included 209 neonates born in the obstetric unit at the 37th gestational week. Based on the results of the TEOAE test, the neonates (...) included in the study were divided into two groups as the study group composed of those "REFER" (n=141) and the control group consisting those "PASS" (n=68) the test. The UCB sampling procedure was performed on all neonates. In the blood samples, the pH parameters were evaluated by using glass electrodes, and the pCO2 and pO2 parameters were evaluated directly by using sensitive electrodes.When the additional maternal diseases were compared with the TEOAE results, the ratio of hypothyroidism was found

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2017 Turkish Archives of Otorhinolaryngology

2. Umbilical Cord Blood Gas Analysis

Umbilical Cord Blood Gas Analysis Umbilical Cord Blood Gas Analysis Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Umbilical Cord (...) Blood Gas Analysis Umbilical Cord Blood Gas Analysis Aka: Umbilical Cord Blood Gas Analysis II. Indications Consider in all high risk deliveries III. Technique Sample obtained immediately after delivery Sample from Umbilical Artery (not the vein) Use preheparinized syringe IV. Interpretation: Normal arterial blood pH: 7.28 +/- 0.05 Unlikely to be significant if >7.10 pCO2: 49 +/- 8.4 pO2: 18 +/- 6.2 HCO3: 22 +/- 2.5 : -4 +/- 2 V. References Images: Related links to external sites (from Bing

2018 FP Notebook

3. Metabolomics Analysis of the Osteogenic Differentiation of Umbilical Cord Blood Mesenchymal Stem Cells Reveals Differential Sensitivity to Osteogenic Agents (PubMed)

Metabolomics Analysis of the Osteogenic Differentiation of Umbilical Cord Blood Mesenchymal Stem Cells Reveals Differential Sensitivity to Osteogenic Agents Mesenchymal stem cells (MSCs) of fetal origin, such as umbilical cord blood MSCs (UCB MSCs), have emerged as a promising cell source for musculoskeletal tissue regeneration because of their higher proliferation potential, lack of donor site morbidity, and their off-the-shelf potential. MSCs differentiated toward the osteogenic lineage (...) exhibit a specific metabolic phenotype characterized by reliance to oxidative phosphorylation for energy production and reduced glycolytic rates. Currently, limited information exists on the metabolic transitions at different stages of the osteogenic process after osteoinduction with different agents. Herein, the osteoinduction efficiency of BMP-2 and dexamethasone on UCB MSCs was assessed using gas chromatography-mass spectrometry (GC-MS) metabolomics analysis, revealing metabolic discrepancies at 7

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2017 Stem cells and development

4. Umbilical cord blood acid-base analysis and the development of significant hyperbilirubinemia in near-term and term newborns: a cohort study (PubMed)

index tests.A cohort of healthy term and near-term newborns underwent umbilical cord hemogasanalysis at birth and capillary heel total serum bilirubin (TSB) pre-discharge, scheduled at 36 h of life, to define the risk of significant hyperbilirubinemia, defined as >9 mg/dL TSB level, ≥ 75th percentile on nomogram of Bhutani et al.It was found that among 537 studied neonates, 133 (24.8%) had pre-discharge TSB levels of >9 mg/dL. When the cord blood gas analysis index tests were compared (...) Umbilical cord blood acid-base analysis and the development of significant hyperbilirubinemia in near-term and term newborns: a cohort study The recognition, follow-up, and early treatment of neonatal jaundice has become more difficult, since the earlier discharge of newborns from hospitals has become common practice. Since intrapartum hypoxic stress has been pointed as predisposing factor for the occurrence of hyperbilirubinemia risk, we tested the association with the cord blood acid-base

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2017 Italian journal of pediatrics

5. Delayed Umbilical Cord Clamping After Birth

on arterial and venous blood gases and lactate concentrations. BJOG 2008;115:697–703. [ ] [ ] Valero J, Desantes D, Perales-Puchalt A, Rubio J, Diago Almela VJ, Perales A. Effect of delayed umbilical cord clamping on blood gas analysis. Eur J Obstet Gynecol Reprod Biol 2012;162:21–3. [ ] [ ] De Paco C, Florido J, Garrido MC, Prados S, Navarrete L. Umbilical cord blood acid-base and gas analysis after early versus delayed cord clamping in neonates at term. Arch Gynecol Obstet 2011;283:1011–4. [ ] Al-Wassia (...) cord clamping may delay timely resuscitation efforts, if needed, especially in preterm infants. However, because the placenta continues to perform gas exchange after delivery, sick and preterm infants are likely to benefit most from additional blood volume derived from continued placental transfusion. Another concern is that a delay in umbilical cord clamping could increase the potential for excessive placental transfusion. To date, the literature does not show evidence of an increased risk

2017 American College of Obstetricians and Gynecologists

6. Safety and Efficacy of Autologous Umbilical Cord Blood Stem Cells Infusion for Preterm Infants.

Umbilical Cord Blood Stem Cells Therapy Autologous Umbilical Cord Blood Stem Cells Therapy,the dose is 5×107cells/kg, 6 and 24 hours after birth Outcome Measures Go to Primary Outcome Measures : Short-term safety of autologous umbilical cord blood stem cell infusion for preterm infants [ Time Frame: during infusion ] vital signs blood gas analysis blood routine liver and kidney function before and after infusion will be compared with the control group. Short-term safety of autologous umbilical cord (...) blood stem cell infusion for preterm infants [ Time Frame: 6 hours after infusion ] vital signs blood gas analysis blood routine liver and kidney function before and after infusion will be compared with the control group. Short-term safety of autologous umbilical cord blood stem cell infusion for preterm infants [ Time Frame: 24 hours after infusion ] vital signs blood gas analysis blood routine liver and kidney function before and after infusion will be compared with the control group. Long-term

2018 Clinical Trials

7. Delayed cord clamping and cord gas analysis at birth. (PubMed)

clamping with the cord still unclamped. Paired blood samples (one from the umbilical artery and one from the umbilical vein) can be taken from the pulsating and unclamped cord, immediately after birth, during delayed cord clamping, without any effect on either the accuracy of umbilical artery gas analysis or the transfusion of blood through delayed cord clamping. Umbilical artery gas analysis should instead not be done after delayed cord clamping, since delayed cord clamping alters several acid-based (...) Delayed cord clamping and cord gas analysis at birth. Delayed cord clamping for at least 60 s in both term and preterm babies is a major recent change in clinical care. Delayed cord clamping has several effects on other possible interventions. One of these is the effect of delayed cord clamping on umbilical artery gas analysis. When indicated, umbilical artery gas analysis can safely be done either with early cord clamping or, probably most of the times it is necessary, during delayed cord

2017 Acta Obstetricia et Gynecologica Scandinavica

8. Metabolic profiling of umbilical cord blood in macrosomia. (PubMed)

singletons with normal maternal glucose tolerance [50 cases (macrosomia, birth weight ⩾4000 g); 50 controls (normal weight, birth weight 2500-3999 g)]. Metabolites in umbilical cord blood were detected using an untargeted metabolomic approach based on gas chromatography/mass spectrometry. We performed logistic regression to evaluate the associations between metabolites and macrosomia. We also performed pathway analysis based on KEGG and MBRole.Compared with controls, the macrosomia cases had a greater (...) Metabolic profiling of umbilical cord blood in macrosomia. The term macrosomia is used to describe neonates with a birth weight of 4000 g or more. Macrosomia is a potential risk factor for obesity and metabolic syndromes in postnatal and adult life, yet little is known about its associations with metabolic difference in the early age. We performed metabolic profiling of umbilical cord blood to discover differential metabolites of macrosomia.We conducted a case-control study of full-term

2017 International Journal of Obesity

9. Clamping of the Umbilical Cord and Placental Transfusion

-Westas L, Andersson D, Clausen J, Domellöf M. Effects of delayed compared with early umbilical cord clamping on maternal postpartum hemorrhage and cord blood gas sampling: a randomized trial. Acta Obstet Gynecol Scand 2013;92:567–74. 36. Grantham-McGregor S, Ani C. A review of studies on the effect of iron deficiency on cognitive development in children. J Nutr 2001;131:649S–666S; discussion 666S–668S. 37 . Sherriff A, Emond A, Bell JC, Golding J; ALSPAC Study Team. Should infants be screened (...) Clamping of the Umbilical Cord and Placental Transfusion Clamping of the Umbilical Cord and Placental T ransfusion Scientific Impact Paper No. 14 February 2015Scientific Impact Paper No. 14 © Royal College of Obstetricians and Gynaecologists 2 of 9 Clamping of the Umbilical Cord and Placental Transfusion 1. Background After birth, blood flow in the umbilical arteries and veins usually continues for a few minutes. The additional blood volume transferred to the baby during this time is known

2015 Royal College of Obstetricians and Gynaecologists

10. Umbilical Cord Prolapse

Perinatal death has been described with normally formed term babies, especially during home births. 1,15,17 Delay in diagnosis to delivery because transfer to hospital is required appears to be a contributing factor. 1 The principal causes of asphyxia in this context are thought to be cord compression and umbilical arterial vasospasm preventing venous and arterial blood flow to and from the fetus. There is a paucity of long-term follow-up data of babies born alive after cord prolapse in both hospital (...) to articles published between June 2005 and October 2012 and limited to humans and the English language. A top-up literature search was performed in July 2014. Search terms included ‘umbilical cord’, ‘cord’, ‘cord prolapse’, ‘delayed cord clamping’ and ‘funic (cord)’. Selection of articles for analysis and review was then made based on relevance to objectives. Further documents were obtained by the use of free text terms and hand searches. The levels of evidence and the grades of recommendations used

2014 Royal College of Obstetricians and Gynaecologists

11. Accuracy of intrapartum fetal blood gas analysis by scalp sampling: A retrospective cohort study. (PubMed)

). To this end, we conducted a retrospective cohort study of singleton term deliveries with NRFHRT according to Fédération Internationale de Gynécologie et d'Obstétrique and Fisher cardiotocography scores undergoing FBGA in a university hospital. The PPV and NPV of FBGA regarding neonatal acidosis (defined as a pH value ≤ 7.15 in arterial or venous umbilical cord blood) and Apgar scores indicating neonatal depression (defined as a 5-min Apgar score ≤5) were evaluated. Multivariate analysis was used (...) Accuracy of intrapartum fetal blood gas analysis by scalp sampling: A retrospective cohort study. Fetal blood gas analysis (FBGA) using scalp blood is commonly used to identify serious fetal distress. However, there is a lack of data regarding its accuracy and reliability. The aim of this study was to determine the positive predictive value (PPV) and negative predictive value (NPV) of FBGA for predicting postpartum acidosis in case of nonreassuring fetal heart rate tracings (NRFHRT

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2017 Medicine

12. Supplemental Oxygen Study: A Randomized Controlled Study on the Effect of Maternal Oxygen Supplementation during Planned Cesarean Delivery on Umbilical Cord Gases. (PubMed)

Supplemental Oxygen Study: A Randomized Controlled Study on the Effect of Maternal Oxygen Supplementation during Planned Cesarean Delivery on Umbilical Cord Gases.  The aim was to determine the fetal umbilical blood gas effects of supplemental maternal oxygenation compared with room air (RA) during term planned cesarean delivery. This is a prospective randomized controlled study of singleton planned cesarean deliveries randomized to receive supplemental oxygen (O2) at 10 L per minute (L/min (...) ). The median umbilical venous pO2 was significantly increased in the supplemental O2 group (32 [26.5-36.0] mm Hg) versus RA group (28.5 [22-34.3] mm Hg), p = 0.04). There were no significant differences with other umbilical blood gas values and composite maternal or neonatal complications. Subjects with term singleton gestations receiving O2 at 10 L/min during cesarean delivery compared with RA demonstrated no significant change in umbilical cord pH values. There was a significant increase in umbilical

2018 American journal of perinatology

13. Effects of delayed compared with early umbilical cord clamping on maternal postpartum hemorrhage and cord blood gas sampling: a randomized trial. (PubMed)

Effects of delayed compared with early umbilical cord clamping on maternal postpartum hemorrhage and cord blood gas sampling: a randomized trial. To investigate the effect of delayed cord clamping (DCC) compared with early cord clamping (ECC) on maternal postpartum hemorrhage (PPH) and umbilical cord blood gas sampling.Secondary analysis of a parallel-group, single-center, randomized controlled trial.Swedish county hospital.382 term deliveries after a low-risk pregnancy.Deliveries were (...) randomized to DCC (≥180 seconds, n = 193) or ECC (≤10 seconds, n = 189). Maternal blood loss was estimated by the midwife. Samples for blood gas analysis were taken from one umbilical artery and the umbilical vein, from the pulsating unclamped cord in the DCC group and from the double-clamped cord in the ECC group. Samples were classified as valid when the arterial-venous difference was -0.02 or less for pH and 0.5 kPa or more for pCO2 . Main outcome measures. PPH and proportion of valid blood gas

2013 Acta Obstetricia et Gynecologica Scandinavica

14. Effects of delayed compared with early umbilical cord clamping on maternal postpartum hemorrhage and cord blood gas sampling: a randomized trial. (PubMed)

Effects of delayed compared with early umbilical cord clamping on maternal postpartum hemorrhage and cord blood gas sampling: a randomized trial. To investigate the effect of delayed cord clamping (DCC) compared with early cord clamping (ECC) on maternal postpartum hemorrhage (PPH) and umbilical cord blood gas sampling.Secondary analysis of a parallel-group, single-center, randomized controlled trial.Swedish county hospital.382 term deliveries after a low-risk pregnancy.Deliveries were (...) randomized to DCC (≥180 seconds, n = 193) or ECC (≤10 seconds, n = 189). Maternal blood loss was estimated by the midwife. Samples for blood gas analysis were taken from one umbilical artery and the umbilical vein, from the pulsating unclamped cord in the DCC group and from the double-clamped cord in the ECC group. Samples were classified as valid when the arterial-venous difference was -0.02 or less for pH and 0.5 kPa or more for pCO2 . Main outcome measures. PPH and proportion of valid blood gas

2013 Acta Obstetricia et Gynecologica Scandinavica

15. Safety of umbilical cord milking in very preterm neonates: a randomized controlled study (PubMed)

morbidity and mortality data, were collected and analyzed.Of the 66 preterm deliveries included in the study, 34 were randomized into the milking and 32 into the clamping group. Differences between maternal pre- and post-partum hemoglobin levels were 1.35 g/dL in the milking and 1.58 g/dL in the clamping group (P=0.451). Neonatal Apgar scores at both 1 and 5 minutes, initial blood gas analysis results, body temperature at admission, need for early intubation, and maximum bilirubin levels were all (...) similar between the 2 groups. However, neonatal hemoglobin levels at birth (15.79 vs. 14.69 g/dL; P<0.05) and at 24 hours of age (14.83 vs. 13.29 g/dL; P<0.05) were significantly higher in the milking group. Neonates in the clamping group required more blood transfusion (1.78 vs. 0.93; P=0.049), and a higher percentage of neonates in the clamping group required inotropic drugs (63% vs. 29%; P=0.007). The mortality rate was significantly lower in the milking group (6% vs. 28%; P=0.015).Umbilical cord

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2017 Obstetrics & gynecology science

16. Umbilical cord blood acid-base and gas analysis after early versus delayed cord clamping in neonates at term. (PubMed)

Umbilical cord blood acid-base and gas analysis after early versus delayed cord clamping in neonates at term. To compare umbilical cord acid-base status and blood gas analysis between umbilical cords clamped within 10 s and at 2 min of delivery.A total of 158 healthy full-term mothers were randomly assigned to an early clamping (<10 s post-delivery, n = 79) or delayed clamping (2 min post-delivery, n = 79) group. After application of inclusion criteria, umbilical vein blood acid-base status (...) and gases were analyzed in 65 early clamped and 51 delayed clamped cords. Fewer cases could be examined in the umbilical artery: 55 cords in the early clamping group and 44 in the delayed one.Acid-base and gas analysis results did not significantly differ between the groups in the umbilical vein or umbilical artery, with the exception of a higher (p < 0.001) mean umbilical artery pO(2) value in the delayed versus early clamping group. No significant differences in umbilical vein or artery pCO(2) or HCO

2011 Archives of gynecology and obstetrics

17. Umbilical Cord Blood Gas Analysis

Umbilical Cord Blood Gas Analysis Umbilical Cord Blood Gas Analysis Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Umbilical Cord (...) Blood Gas Analysis Umbilical Cord Blood Gas Analysis Aka: Umbilical Cord Blood Gas Analysis II. Indications Consider in all high risk deliveries III. Technique Sample obtained immediately after delivery Sample from Umbilical Artery (not the vein) Use preheparinized syringe IV. Interpretation: Normal arterial blood pH: 7.28 +/- 0.05 Unlikely to be significant if >7.10 pCO2: 49 +/- 8.4 pO2: 18 +/- 6.2 HCO3: 22 +/- 2.5 : -4 +/- 2 V. References Images: Related links to external sites (from Bing

2015 FP Notebook

18. Timing of umbilical cord clamping for neonatal and maternal outcomes

, maternal postpartum haemorrhage, manual removal of retained placenta and correct sampling for blood gas analysis? Final publication URL Additional data URL Indexing Status Subject indexing assigned by CRD MeSH Anemia, Iron-Deficiency; Humans; Infant, Newborn; Infant, Premature; Pregnancy; Time Factors; Umbilical Cord Language Published English Country of organisation Sweden English summary An English language summary is available. Address for correspondence The Regional Health Technology Assessment (...) Timing of umbilical cord clamping for neonatal and maternal outcomes Timing of umbilical cord clamping for neonatal and maternal outcomes Timing of umbilical cord clamping for neonatal and maternal outcomes Wennerholm UB, Daxberg EL, Fasth A, Holmberg Y, Jangsten E, Stigson L, Strandell A, Jivegård L Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality of this assessment has been made for the HTA database. Citation Wennerholm UB

2012 Health Technology Assessment (HTA) Database.

19. The effect of time, temperature and storage device on umbilical cord blood gas and lactate measurement: a randomized controlled trial. (PubMed)

The effect of time, temperature and storage device on umbilical cord blood gas and lactate measurement: a randomized controlled trial. Umbilical cord blood gas analysis has a significant and growing role in early neonatal assessment. Factors often delay analysis of cord blood allowing values to change. Consequently, this study evaluates the impact of time, temperature and method of storage on umbilical blood gas and lactate analyses.Umbilical cord segments from 80 singleton deliveries were (...) minutes). Arterial base excess deteriorated in CR and SI (p ≤ 0.009; 15 minutes), SR (p < 0.001; 30 minutes), and CI (p < 0.001; 45 minutes). Arterial lactate levels increased within 15 minutes in all groups (p < 0.001).Cord blood gas values change rapidly after delivery. Smallest changes were seen in SR group. Data suggest that analyses should be conducted as soon as possible after delivery.

2012 The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians

20. Comparison of fetal middle cerebral arteries, umbilical and uterin artery color Doppler ultrasound with blood gas analysis in pregnancy complicated by IUGR (PubMed)

Comparison of fetal middle cerebral arteries, umbilical and uterin artery color Doppler ultrasound with blood gas analysis in pregnancy complicated by IUGR Fetal color Doppler is important for evaluation of hypoxia in intrauterine growth restriction (IUGR) fetus.In this study we compare fetal and maternal color Doppler with blood gas analysis to detect fetal acidosis.In this cross-sectional study we evaluated 100 hospitalized patients with IUGR for comparison of color Doppler results (...) with arterial blood gas analysis. RESULTS of Doppler sonography of fetus middle cerebral arteries, umbilical and uterine artery and umbilical artery ABG were studied in these neonates.Mean maternal age was 28±7 years, mean gestational age was 31.79±2.59 weeks and mean growth restriction was 3±2 weeks. Resistance increasing was observed in right uterine arteries of 37 mothers. It was normal in 60 mothers. Resistance increasing was observed in left uterine arteries of 36 mothers and nuch was seen in four

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2013 Iranian Journal of Reproductive Medicine

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