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Treating Family Members

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81. Engaging High Risk Families in Home Visiting Programs: A Rapid Review

should treat parents in a non- stigmatizing and supportive way. (8) Uptake of home visiting programs is influenced by parents’ perceived needs, confidence levels and desire for practical support. (6) Participation is also influenced by families’ culture and language. (6) Parental perception of the quality of the intervention can be affected when parents worry about staff prying into their personal lives. (6) If a program targets ‘disadvantaged’ families, this label may accentuate the sense of failure (...) the length or frequency of visits, and providing flexible hours, including evenings and weekends, allows working parents, partners, and other family members to participate. (6-8) When a client is disengaged and may consider dropping out, staff should change the content being delivered and/or offer a break from the program. (6) During breaks from the program, the nurse should maintain regular communication with parents. (6) It is key that staff are flexible to the needs of the client by ensuring services

2018 Peel Health Library

82. Marriage and Family Building Equality for Lesbian, Gay, Bisexual, Transgender, Queer, Intersex, Asexual, and Gender Nonconforming Individuals

resources. Obstetrician–gynecologists should do the following: Work to understand, recognize, and address the challenges the LGBTQIA and gender nonconforming communities experience in accessing reproductive health care, including family building. Work to eliminate overt and covert discriminatory procedures and practices in their clinical spaces through creation of affirming and welcoming environments. Understand that members of the LGBTQIA and gender nonconforming communities may desire family building (...) in accessing the resources available to support the health and growth of their families. Research has consistently demonstrated that members of these communities can provide loving, safe, and healthy homes for children ( ). Family building for these communities includes multiple modalities, but some may require assisted reproductive technologies or adoption ( , ). Persistent stigmatization of the LGBTQIA and gender nonconforming communities may result in difficulty finding physicians to assist

2018 American College of Obstetricians and Gynecologists

83. Hadiza Bawa-Garba could have been any member of frontline staff working in today’s overstretched NHS

bereaved family members have accused doctors of self-interest, complacency and the belief they are “untouchable,” while some angry doctors have accused their Twitter critics of cowardice. High emotions, ramped up by the constraints of 280 characters, on both sides. What, at root, is driving the outrage? From my experience as a doctor, I believe that most of us—patients, families, colleagues and me—tend to be prone to anger when we are scared. Right now, this case makes me terrified. We know that Bawa (...) Hadiza Bawa-Garba could have been any member of frontline staff working in today’s overstretched NHS Hadiza Bawa-Garba could have been any member of frontline staff working in today’s overstretched NHS - The BMJ ---> The only way to improve patient safety is to talk openly about everything that contributes to patient harm, says Rachel Clarke It almost makes me flinch to imagine it. Anxious parents, consumed with fear, rush their limp and vomiting six-year-old to hospital. Yet mistakes are made

2017 The BMJ Blog

84. Treating Opioid Use Disorder During Pregnancy: Guideline Supplement

. The application of the recommendations in this guideline does not override the responsibility of health care professionals to make decisions appropriate to the circumstances of an individual patient, in consultation with that patient and their guardian(s) or family members, and, when appropriate, external experts (e.g., specialty consultation). Nothing in this guideline should be interpreted in a way that would be inconsistent with compliance with those duties. Legal Disclaimer While the individuals (...) Treating Opioid Use Disorder During Pregnancy: Guideline Supplement 1 Guideline Supplement Treatment of Opioid Use Disorder During2 THIS IS A BLANK PAGE3 A Guideline for the Clinical Management of Opioid Use Disorder—Pregnancy Supplement The BC Centre on Substance Use (BCCSU) is a provincially networked platform mandated to develop, imple- ment, and evaluate evidence-based approaches to substance use and addiction. The BCCSU’s focus is on three strategic areas including research and evaluation

2018 British Columbia Perinatal Health Program

85. AASLD-IDSA Recommendations for Testing, Managing, and Treating Hepatitis C Virus Infection

childhood activities without restrictions. I, B Parents should be informed that universal precautions should be followed at school and in the home of children with HCV infection. Educate family members and children about the risk and routes of HCV transmission and the techniques for avoiding blood exposure, such as avoiding the sharing of toothbrushes, razors, and nail clippers and the use of gloves and dilute bleach to clean up blood. I, B Abbreviation: HCV, hepatitis C virus. Table 8. Recommendations (...) AASLD-IDSA Recommendations for Testing, Managing, and Treating Hepatitis C Virus Infection Clinical Infectious Diseases • CID 2018:67 (15 November) • 1477 2018 AASLD-IDSA Hepatitis C Guidance Hepatitis C Guidance 2018 Update: AASLD-IDSA Recommendations for Testing, Managing, and Treating Hepatitis C Virus Infection AASLD-IDSA HCV Guidance Panel a (See the Commentary by Jhaveri etal on pages 1493–7.) Recognizing the importance of timely guidance regarding the rapidly evolving field of hepatitis

2019 American Association for the Study of Liver Diseases

86. How do biosimilar medications compare to their corresponding originator biologic medications in treating patients with conditions like rheumatoid arthritis or inflammatory bowel disease?

How do biosimilar medications compare to their corresponding originator biologic medications in treating patients with conditions like rheumatoid arthritis or inflammatory bowel disease? Tools for Practice is proudly sponsored by the Alberta College of Family Physicians (ACFP). ACFP is a provincial, professional voluntary organization, representing more than 4,800 family physicians, family medicine residents, and medical students in Alberta. Established over sixty years ago, the ACFP strives (...) for excellence in family practice through advocacy, continuing medical education and primary care research. www.acfp.ca May 27, 2019 It’s all in the details... or is it? Biosimilars versus biologics for inflammatory conditions. Clinical Question: How do biosimilar medications compare to their corresponding originator biologic medications in treating patients with conditions like rheumatoid arthritis or inflammatory bowel disease? Bottom Line: For patients with rheumatoid arthritis, other inflammatory

2019 Tools for Practice

87. Should family physicians treat members of the same family?: YES (Full text)

Should family physicians treat members of the same family?: YES 21626893 2011 09 01 2011 05 31 1715-5258 57 4 2011 Apr Canadian family physician Medecin de famille canadien Can Fam Physician Should family physicians treat members of the same family?: YES. 402-4 Karazivan Philippe P Notre Dame Family Medicine Unit, Montreal, Quebec, Canada. philippe.karazivan@umontreal.ca eng fre Journal Article Canada Can Fam Physician 0120300 0008-350X IM Confidentiality Conflict of Interest Family Family

2011 Canadian Family Physician PubMed

88. Should family physicians treat members of the same family?: NO (Full text)

Should family physicians treat members of the same family?: NO 21490349 2011 09 01 2011 09 05 1715-5258 57 4 2011 Apr Canadian family physician Medecin de famille canadien Can Fam Physician Should family physicians treat members of the same family?: NO. 403-4 Pless Charles C e-mail plesscharles@hotmail.com. eng Journal Article Canada Can Fam Physician 0120300 0008-350X IM Confidentiality Conflict of Interest Family Family Practice ethics Humans Physician-Patient Relations ethics 2011 4 15 6 0

2011 Canadian Family Physician PubMed

89. Psychiatric Neurosurgery (PNS) for Obsessive Compulsive Disorder (OCD): A Qualitative Analysis of Patient and Family Member Experiences

Electrical stimulation of the anterior limb of the internal capsule or bed nucleus of the stria terminalis Deep Brain Stimulation Family Members Family members of patients who have previously been treated with a deep brain stimulation procedure for obsessive compulsive disorder will be included in this group Anterior Capsulotomy Patients Patients who have previously been treated with an anterior capsulotomy procedure for obsessive compulsive disorder will be included in this group Procedure: anterior (...) capsulotomy Anterior Capsulotomy Family Members Family members of patients who have previously been treated with an anterior capsulotomy procedure for obsessive compulsive disorder will be included in this group Outcome Measures Go to Primary Outcome Measures : Semi-structured Interview [ Time Frame: up to 180 months after surgery ] A semi-structured interview of patients and one of their family members will be conducted. Patients and family members will be interviewed separately. The interview

2015 Clinical Trials

90. Preferences of Current and Potential Patients and Family Members Regarding Implementation of Electronic Communication Portals in Intensive Care Units. (PubMed)

members of patients currently admitted to ICUs at an academic medical center in Boston (cohort C).Respondents, especially current ICU family members, supported an electronic communication portal, including access via an electronic tablet. They wanted at least daily updates, one-paragraph summaries of family meetings including a list of key decisions made, and knowledge of the role and experience of treating clinicians. Overall, they preferred detailed rather than "big picture" information. Respondents (...) Preferences of Current and Potential Patients and Family Members Regarding Implementation of Electronic Communication Portals in Intensive Care Units. The quality of communication with patients and family members in intensive care units (ICUs) is a focus of current interest for clinical care improvement. Electronic communication portals are commonly used in other healthcare settings to improve communication. We do not know whether patients and family members desire such portals in ICUs

2015 Annals of the American Thoracic Society

91. Novel therapeutic interventions for p53-altered tumors through manipulation of its family members, p63 and p73 (Full text)

Novel therapeutic interventions for p53-altered tumors through manipulation of its family members, p63 and p73 TP53 is highly mutated in human cancers, thus targeting this tumor suppressor pathway is highly desirable and will impact many cancer patients. (1,2) Therapeutic strategies to reactivate the p53-pathway have been challenging, (3,4) and no effective treatment exists. (5) We utilized the p53-family members, p63 and p73, which are not frequently mutated in cancer, to treat p53-defective (...) target ΔNp63 and ΔNp73 to treat cancer patients with alterations in p53.

2015 Cell Cycle PubMed

92. Clinical Presentation, Long-Term Follow-Up, and Outcomes of 1001 Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy Patients and Family Members. (Full text)

from a cardiac cause (2% versus 0%) than family members without mutations.Long-term outcome was favorable in diagnosed and treated ARVD/C index-patients and family members. Outcome in index-patients was modulated by implantable cardioverter-defibrillator implantation, but not by mutation status and familial background of disease. One third of family members developed ARVD/C. Outcome in family members was determined by symptoms at first evaluation and mutations.© 2015 American Heart Association, Inc. (...) Clinical Presentation, Long-Term Follow-Up, and Outcomes of 1001 Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy Patients and Family Members. Arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) is a progressive cardiomyopathy. We aimed to define long-term outcome in a transatlantic cohort of 1001 individuals.Clinical and genetic characteristics and follow-up data of ARVD/C index-patients (n=439, fulfilling of 2010 criteria in all) and family members (n=562) were

2015 Circulation. Cardiovascular genetics PubMed

93. Autoantibodies binding to ubiquitin-fold modifier-conjugating enzyme 1 (Ufc1) and pleckstrin homology domain containing, family G (with RhoGef domain) member 2 (Plekhg2) are associated with mycobacterial infections. (Full text)

Autoantibodies binding to ubiquitin-fold modifier-conjugating enzyme 1 (Ufc1) and pleckstrin homology domain containing, family G (with RhoGef domain) member 2 (Plekhg2) are associated with mycobacterial infections. The diagnosis of extrapulmonary tuberculous infections and nontuberculous mycobacterial (NTM) infections is difficult because the symptoms are nonspecific and suitable specimens for bacterial culture are often not available. Recent publications reported the existence (...) of autoantibodies in tuberculous infections. We screened for specific autoantibodies in mycobacterial infections.We screened four in 29 patients with active mycobacterial infections and different controls using protein array technology. We could identify autoantibodies against ubiquitin-fold modifier-conjugating enzyme 1 (Ufc1) and pleckstrin homology domain containing, family G (with RhoGef domain) member 2 (Plekhg2) in all four patients. Subsequently, we designed enzyme-linked immunosorbent assays (ELISAs

2015 HIV medicine PubMed

94. Adapting Alcohol Behavioral Couple Therapy for Service Members in Post-Deployment

of Massachusetts, Worcester Collaborator: National Institute on Alcohol Abuse and Alcoholism (NIAAA) Information provided by (Responsible Party): Elizabeth Epstein, University of Massachusetts, Worcester Study Details Study Description Go to Brief Summary: The specific aims of the ABCT_Military project are as follows: 1) To modify the existing, Alcohol Behavioral Couple Therapy (ABCT) model to treat service members in the reconstitution (post deployment, reintegration, or separation) stage of service (...) the client's ideal number of sessions and length of treatment, with scores ranging from 1 to 24 sessions and 1-12 months. Eligibility Criteria Go to Information from the National Library of Medicine Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Layout

2018 Clinical Trials

95. Pharmacologic Treatment of Hypertension in Adults Aged 60 Years or Older to Higher Versus Lower Blood Pressure Targets: A Clinical Practice Guideline from the American College of Physicians and the American Academy of Family Physicians (Full text)

the journal. The guideline had a peer-review process through the journal and was posted online for comments from ACP Regents and Governors, who represent physician members at the national and international level. The guideline was also reviewed by members of AAFP's Commission on Health of the Public and Science. Benefits of Treating Higher Versus Lower BP Targets in Older Adults Across all trials, treating high BP in older adults was beneficial. However, most of the evidence came from studies of patients (...) Pharmacologic Treatment of Hypertension in Adults Aged 60 Years or Older to Higher Versus Lower Blood Pressure Targets: A Clinical Practice Guideline from the American College of Physicians and the American Academy of Family Physicians Pharmacologic Treatment of Hypertension in Adults | Annals of Internal Medicine | American College of Physicians '); } Sign in below to access your subscription for full content INDIVIDUAL SIGN IN | You will be directed to acponline.org to register and create

2017 American College of Physicians PubMed

96. Identifying and Assessing Core Components of Collaborative-care Models for Treating Mental and Physical Health Conditions

that $2.75 billion is spent on treating individuals with multiple illnesses.(18) From the perspective of service providers included in one study, many family physicians indicated that they feel ill-equipped to care for patients with comorbid physical and mental health and/or substance use problems. This stems in part from the continued “siloed” approach to training mental health professionals compared to other health professionals. A recent survey of family physicians in 10 Commonwealth countries found (...) Identifying and Assessing Core Components of Collaborative-care Models for Treating Mental and Physical Health Conditions McMaster Health Forum McMaster Health Forum 1 Evidence >> Insight >> Action Knowledge Synthesis: Identifying and Assessing Core Components of Collaborative-care Models for Treating Mental and Physical Health Conditions 31 March 2017 Identifying and Assessing Core Components of Collaborative-Care Models for Treating Mental and Physical Health Conditions 2 Evidence >> Insight

2017 McMaster Health Forum

97. Attitudinal concordance toward uptake and disclosure of genetic testing for cancer susceptibility in patient-family member dyads. (PubMed)

a reliable CSGT was available for the specific cancer a patient was being treated. While most patients and family members responded they would uptake or recommend CSGT if available, concordance between the dyads was poor for both patient's testing (agreement rate 77.5%, weighted κ=0.09) and first-degree relatives' testing(agreement rate 78.0%, weighted κ=0.09). Most patients (93.2%) and family members (92.9%) indicated that patients should disclose positive CSGT results to family members, with dyadic (...) Attitudinal concordance toward uptake and disclosure of genetic testing for cancer susceptibility in patient-family member dyads. Decisions for cancer susceptibility genetic testing (CSGT) uptake and dissemination of results occur within the family context. A national survey was performed with 990 patient-family member dyads (participation rate:76.2%), with paired questionnaires examining attitudes toward CSGT uptake and disclosure of results in response to a hypothetical scenario in which

2014 Clinical Genetics

98. Deep Sequencing the microRNA profile in rhabdomyosarcoma reveals down-regulation of miR-378 family members. (Full text)

Deep Sequencing the microRNA profile in rhabdomyosarcoma reveals down-regulation of miR-378 family members. Rhabdomyosarcoma (RMS) is a highly malignant tumour accounting for nearly half of soft tissue sarcomas in children. MicroRNAs (miRNAs) represent a class of short, non-coding, regulatory RNAs which play a critical role in different cellular processes. Altered miRNA levels have been reported in human cancers, including RMS.Using deep sequencing technology, a total of 685 miRNAs were (...) -378 family members were dramatically decreased in RMS tumour tissue and cell lines. Interestingly, members of the miR-378 family presented as a possible target the insulin-like growth factor receptor 1 (IGF1R), a key signalling molecule in RMS. MiR-378a-3p over-expression in an RMS-derived cell line suppressed IGF1R expression and affected phosphorylated-Akt protein levels. Ectopic expression of miR-378a-3p caused significant changes in apoptosis, cell migration, cytoskeleton organization as well

2014 BMC Cancer PubMed

99. Family Physicians Managing Medical Requests From Family and Friends (Full text)

Family Physicians Managing Medical Requests From Family and Friends Although guidelines generally state that physicians should not treat their family members or friends (nonpatients), physicians regularly receive medical requests from nonpatients. We aimed to explore junior and senior family physicians' experiences with and attitudes toward managing medical requests from nonpatients.We conducted a qualitative study with 7 focus groups with junior and senior physicians. We performed a thematic (...) nonpatients. Facilitated group discussions during which experiences are shared can help junior physicians become more confident in dealing with these complex issues as they formulate their own personal strategy regarding provision of medical advice or treatment to family and friends.© 2018 Annals of Family Medicine, Inc.

2018 Annals of family medicine PubMed

100. Homozygous familial hypercholesterolaemia in Vietnam: Case series, genetics and cascade testing of families. (PubMed)

Homozygous familial hypercholesterolaemia in Vietnam: Case series, genetics and cascade testing of families. Familial hypercholesterolaemia has not been previously described in the Vietnamese population. We aimed to describe the features of patients with homozygous familial hypercholesterolaemia (hoFH) in Vietnam and the outcomes of screening family members using genetic and cholesterol testing.Mutation testing by massively parallel sequencing for genes causative of FH was undertaken in five (...) index cases presenting to a single cardiac center with a presumptive diagnosis of hoFH. Cascade testing of all available family members was subsequently undertaken. The number of new cases of FH detected and commenced on lipid-lowering treatment was evaluated.All five index cases had true homozygous mutations in the LDL receptor gene (LDLR). Cascade screening was undertaken in four families. 107 relatives were screened and FH was identified in 56 relatives (52%), including 3 new cases of hoFH. Only

2018 Atherosclerosis

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