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Travelers Diarrhea

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1741. A trial that would revolutionize the world of placebo research

with a court battle and caring for the two youngest of her four children. “I went through hell,” she says. Within a year of the split, she started suffering from intestinal pains, cramps, diarrhea and bloating. The condition has affected her ever since, especially at stressful times such as when she was laid off from the factory. She retrained as a medical assistant, hoping to find work in a chiropractor’s office, but once she qualified she found that no one was hiring. When she did finally find a part (...) . She brightens. “But I travel,” she says. “I go to England, I do every- thing. I love it.” I’m thrown by this statement until I realize that she’s talking about Google maps. I ask her to show me, and we move over to her computer, which sits on a desk squeezed between the sofa and the microwave. She fires up the maps program and lands us on top of Buckingham Palace in London. Suddenly I get a sense of how much time Linda has spent in this flat. She knows the layout of the palace intimately, zooming

2015 KevinMD blog

1742. Imported diseases in general practice. Gastrointestinal disorders. Full Text available with Trip Pro

Imported diseases in general practice. Gastrointestinal disorders. 4611581 1975 02 27 2018 11 13 0007-1447 4 5943 1974 Nov 30 British medical journal Br Med J Imported diseases in general practice. Gastrointestinal disorders. 522-4 Paton A A eng Journal Article England Br Med J 0372673 0007-1447 AIM IM Cholera diagnosis Diarrhea etiology Dysentery, Amebic diagnosis Dysentery, Bacillary diagnosis Escherichia coli isolation & purification Foodborne Diseases microbiology Gastroenteritis etiology (...) microbiology parasitology Giardiasis diagnosis Helminthiasis etiology Hepatitis A diagnosis Humans Malaria diagnosis Salmonella typhimurium isolation & purification Schistosoma mansoni isolation & purification Shigella dysenteriae isolation & purification Shigella flexneri isolation & purification Strongyloidiasis diagnosis Travel Typhoid Fever diagnosis United Kingdom Vibrio cholerae isolation & purification 1974 11 30 1974 11 30 0 1 1974 11 30 0 0 ppublish 4611581 PMC1612630 JAMA. 1971 Sep 6;217(10):1359

1974 British medical journal

1743. Aspects of Tropical Medicine Seen in Family Practice Full Text available with Trip Pro

Aspects of Tropical Medicine Seen in Family Practice The health hazards of jet age travel have been well stressed in the various media, but many Canadians visit the tropics and remain unaware of the potential risks they may encounter. On their return, some of these subjects will seek medical help for such problems as diarrhea and pyrexia, therefore all physicians should be aware of the commoner causes of these and allied symptoms as they relate to tropical and parasitic diseases. The importance

1974 Canadian Family Physician

1744. Outbreake of Marburg virus disease in Johannesburg. Full Text available with Trip Pro

Outbreake of Marburg virus disease in Johannesburg. The first recognised outbreak of Marburg virus disease in Africa, and the first since the original epidemic in West Germany and Yugoslavia in 1967, occurred in South Africa in February 1975. The primary case was in a young Australian man , who was admitted to the Johannesburg Hospital after having toured Rhodesia. Two secondary cases occurred, one being in the first patient's travelling companion, and the other in a nurse. Features (...) of the illness included high fever, myalgia, vomiting and diarrhoea, hepatitis, a characteristic maculopapular rash, leucopenia, thrombocytopenia, and a bleeding tendency. The first patient died on the seventh day from haemorrhage resulting from a combination of disseminated intravascular coagulation and hepatic failure. The other two patients were given vigorous supportive treatment and prophylactic heparin and recovered after an acute phase lasting about seven days. During this period on developed

1975 British medical journal

1745. Immunization and other prophylactic measures. Full Text available with Trip Pro

Immunization and other prophylactic measures. 4613420 1975 04 19 2018 11 13 0007-1447 4 5945 1974 Dec 14 British medical journal Br Med J Immunization and other prophylactic measures. 648-50 Roodyn L L eng Journal Article England Br Med J 0372673 0007-1447 0 Smallpox Vaccine AIM IM Africa Asia Cholera prevention & control Diarrhea prevention & control Eczema complications Europe Female Food Handling Hepatitis prevention & control Humans Immunization Malaria prevention & control Male Meningitis (...) , Meningococcal prevention & control Plasmodium falciparum Poliomyelitis prevention & control Pregnancy Smallpox prevention & control Smallpox Vaccine adverse effects Tetanus prevention & control Travel Typhoid Fever prevention & control Vaccination Yellow Fever prevention & control 1974 12 14 1974 12 14 0 1 1974 12 14 0 0 ppublish 4613420 PMC1612958 Arch Intern Med. 1971 Nov;128(5):723-38 4107518

1974 British medical journal

1746. Symptoms and signs of malaria. Full Text available with Trip Pro

Symptoms and signs of malaria. In addition to asking their patients about recent foreign travel, Canadian doctors need to be aware of what features to ask about in considering imported illnesses. Of these illnesses, malaria is one of the most common and serious. Because of its cerebral renal, pulmonary and intestinal complications, falciparum malaria must be distinguished from non-falciparum forms. Anyone with a fever who has arrived recently from an endemic area should be tested for malaria (...) . In addition, headache, malaise, myalgias, arthralgias, low back pain, nausea, vomiting, diarrhea or cough should raise suspicion. Malaria should be remembered as a cause of coma. Persons taking any form of drug prophylaxis for malaria are not protected absolutely and those who are semi-immune can become severely ill occasionally.

1976 Canadian Medical Association Journal

1747. A case of cholera in Kingston, Ont. Full Text available with Trip Pro

A case of cholera in Kingston, Ont. A case of cholera occurred in Kingston, Ont. in 1974 in a traveller from South Africa. Treatment, based on an understanding of the pathophysiology of cholera diarrhea and the mechanism of action of the Vibrio cholerae enterotoxin on gastrointestinal fluid loss, consisted of correcting the severe loss of fluid and electrolytes and the metabolic acidosis, as soon as the patient could tolerate taking fluids orally, further fluid replacement consisted

1976 Canadian Medical Association Journal

1748. The Kenya general practitioner looks at the tourist. Full Text available with Trip Pro

The Kenya general practitioner looks at the tourist. 4677919 1972 12 17 2008 11 20 0035-8797 22 122 1972 Sep The Journal of the Royal College of General Practitioners J R Coll Gen Pract The Kenya general practitioner looks at the tourist. 645-7 Cunningham G A GA eng Journal Article England J R Coll Gen Pract 7503107 0035-8797 IM Adolescent Adult Aged Child Child, Preschool Diarrhea epidemiology Family Practice Female Humans Kenya Malaria epidemiology Male Middle Aged Morbidity Otitis (...) epidemiology Respiratory Tract Infections epidemiology Sexually Transmitted Diseases epidemiology Travel Vomiting epidemiology Wounds and Injuries epidemiology 1972 9 1 1972 9 1 0 1 1972 9 1 0 0 ppublish 4677919 PMC2156242

1972 The Journal of the Royal College of General Practitioners

1749. Management of patients recently arrived from the tropics. Full Text available with Trip Pro

Management of patients recently arrived from the tropics. 4318277 1970 10 17 2018 11 13 0007-1447 3 5720 1970 Aug 22 British medical journal Br Med J Management of patients recently arrived from the tropics. 447-9 Rowland H A HA eng Journal Article England Br Med J 0372673 0007-1447 AIM IM Amebiasis diagnosis Diarrhea etiology Dysentery, Bacillary diagnosis Emigration and Immigration Entamoeba histolytica Fever diagnosis Giardiasis diagnosis Humans Skin Diseases diagnosis Sprue, Tropical (...) diagnosis Travel Tropical Medicine United Kingdom 1970 8 22 1970 8 22 0 1 1970 8 22 0 0 ppublish 4318277 PMC1701420 Br Med J. 1969 Jun 28;2(5660):781-5 4891335

1970 British medical journal

1750. Campylobacter enteritis: a "new" disease. Full Text available with Trip Pro

Campylobacter enteritis: a "new" disease. By selective culture campylobacters (C jejuni and C coli) were isolated from the faeces of 57 (7-1%) out of 803 unselected patients with diarrhoea; none were isolated from 194 people who had not got diarrhoea. Specific agglutinins were found in the sera of 31 out of 38 patients with campylobacter enteritis and 10 of them had a rising titre. Half the patients were aged 15 to 44 years, but the incidence was highest in young children. All the patients (...) with campylobacters had a distinctive clinical illness with severe abdominal pain. Campylobacters are a relatively unrecognised cause of acute enteritis, but these findings suggest that they may be a common cause. Spread of infection was observed within 12 out of 29 households, and in these cases children were usually implicated. Several patients were apparently infected from chickens, both live and dressed, and poultry may be the primary source of the organism. In two cases dogs with diarrhoea were found

1977 British medical journal

1751. Immunity to Enterotoxigenic Escherichia coli Full Text available with Trip Pro

Immunity to Enterotoxigenic Escherichia coli Enterotoxigenic Escherichia coli strains represent the most frequent etiological agent of travelers diarrhea. Challenge studies with several of these strains were undertaken in volunteers to evaluate the mechanisms of disease-induced immunity. Seventeen students and other community volunteers were given 10(6) or 10(8) organisms of E. coli B7A (O148:H28), which produces heat-labile and heat-stable enterotoxins. Ten individuals developed diarrheal (...) illness closely resembling natural travelers diarrhea; of these ten, rises in titer of serum antitoxin and anti-O antibody occurred in eight (80%). Eight of the volunteers who developed diarrhea in the first test agreed to undergo rechallenge 9 weeks later with 10(8) B7A organisms. Only one of these eight "veterans" developed diarrhea versus seven of twelve controls given the same challenge (P = 0.05). Despite clinical protection, all "veterans" excreted B7A after rechallenge. Four controls who

1979 Infection and immunity

1752. Delhi belly, Hong Kong dog, Casablanca crud, Montezuma's revenge, Turista. Full Text available with Trip Pro

Delhi belly, Hong Kong dog, Casablanca crud, Montezuma's revenge, Turista. 4570093 1973 05 02 2018 11 13 0008-1264 118 3 1973 Mar California medicine Calif Med Delhi belly, Hong Kong dog, Casablanca crud, Montezuma's revenge, Turista. 37-8 Goldsmith R R eng Journal Article United States Calif Med 0410260 0008-1264 IM Diarrhea epidemiology microbiology prevention & control Escherichia coli isolation & purification Humans Travel 1973 3 1 1973 3 1 0 1 1973 3 1 0 0 ppublish 4570093 PMC1455114 Med

1973 California Medicine

1753. New Surface-Associated Heat-Labile Colonization Factor Antigen (CFA/II) Produced by Enterotoxigenic Escherichia coli of Serogroups O6 and O8 Full Text available with Trip Pro

for humans since CFA/II-positive ETEC are frequently isolated from diarrhea cases, particularly travelers' diarrhea, in Mexico; these ETEC were not uncommon in a collection of isolates from Bangladesh. The O6:H16 strain of ETEC responsible for an outbreak of diarrhea in the United States was also shown to be CFA/II positive. CFA/I and CFA/II were never found on the same serotypes of ETEC, but 98% of the heat-stable and heat-labile enterotoxin-producing ETEC belonging to the frequently isolated serogroups

1978 Infection and immunity

1754. Hong Kong dog and the Tokyo trots. Full Text available with Trip Pro

Hong Kong dog and the Tokyo trots. 93013 1980 03 27 2013 11 21 0007-1447 2 6199 1979 Nov 10 British medical journal Br Med J Hong Kong dog and the Tokyo trots. 1225 Thubron R S RS eng Letter England Br Med J 0372673 0007-1447 0 Drug Combinations 0 Sulfathiazoles 0N7609K889 Sulfadiazine 15XQ8043FN Sulfaguanidine 48U51W007F Sulfamethazine T7D4876IUE Dihydrostreptomycin Sulfate AIM IM Diarrhea drug therapy Dihydrostreptomycin Sulfate therapeutic use Drug Combinations Humans Sulfadiazine (...) therapeutic use Sulfaguanidine therapeutic use Sulfamethazine therapeutic use Sulfathiazoles therapeutic use Travel 1979 11 10 1979 11 10 0 1 1979 11 10 0 0 ppublish 93013 PMC1597259

1979 British medical journal

1755. Pediatric Gastroesophageal Reflux Clinical Practice Guidelines

in infants with regurgitation or vomiting Bilious vomiting Gastrointestinal bleeding Hematemesis Hematochezia Consistently forceful vomiting Onset of vomiting after 6months of life Failure to thrive Diarrhea Constipation Fever Lethargy Hepatosplenomegaly Bulging fontanelle Macro/microcephaly Seizures Abdominal tenderness or distension Documented or suspected genetic/metabolic syndrome 506 NASPGHAN/ESPGHAN PEDIATRIC GER GUIDELINE COMMITTEE J Pediatr Gastroenterol Nutr, Vol. 49, No. 4, October

2009 North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition

1756. Safety of Probiotics to Reduce Risk and Prevent or Treat Disease

for preventing adverse events caused by other treatments such as antibiotic treatment. That is, studies in which efficacy outcomes were identical with adverse events (e.g., prevention of antibiotic-induced diarrhea) were not considered for this review, as further outlined in the inclusion criteria. This restriction required careful review of individual studies, but has also been imposed in other safety reviews (e.g., Pitrou, Boutron, Ahmad & Ravand, 2009), and an overview of the efficacy and effectiveness

2011 EvidenceUpdates

1757. Clopidogrel versus other antiplatelet agents for secondary prevention of vascular events in adults with acute coronary syndrome or peripheral vascular disease: clinical and cost-effectiveness analyses

has received honoraria for talks from Sanofi-aventis and Bristol-Myers Squibb (among others); and he has participated in the development of accredited continuing medication education (CME) activities that were sponsored by these companies and an advisory board. Dr. Mukul Sharma has received support for speaking engagements and travel, and honoraria as an advisory board member from Bristol- Myers Squibb, Sanofi-Aventis, and Boehringer Ingelheim (Canada) Ltd. Clopidogrel versus Other Antiplatelet

2011 EvidenceUpdates

1758. Measles

. In the US, almost all measles cases are imported by travelers or immigrants, with subsequent indigenous transmission occurring primarily among unvaccinated people. Symptoms and Signs After a 7- to 14-day incubation period, measles begins with a prodrome of fever, coryza, hacking cough, and tarsal conjunctivitis. Pathognomonic Koplik spots appear during the prodrome, before the onset of rash, usually on the oral mucosa opposite the 1st and 2nd upper molars. The spots resemble grains of white sand (...) longer, causing morbidity or death. Transient hepatitis and diarrhea may occur during an acute infection. (SSPE) is a rare, progressive, ultimately fatal, late complication of measles. Atypical measles syndrome is a complication that occurred in people vaccinated with the original killed-virus measles vaccines, which have not been used since 1968. These older vaccines altered disease expression in some patients who were incompletely protected and subsequently infected with wild-type measles. Measles

2013 Merck Manual (19th Edition)

1759. Genital Herpes

vaccination, the current threat of a smallpox outbreak is most likely to come from which of the following? Bioterrorism Immunodeficiency Travel abroad Vaccination refusal NEWS & VIDEOS Hospital-Onset MRSA Decreased From 2002 to 2015 WEDNESDAY, March 6, 2019 (HealthDay News) -- Staphylococcus aureus infections are still a concern in the United States, despite a decline seen in hospital-onset methicillin-resistant S. aureus... Video Overview of Lyme Disease SOCIAL MEDIA Add to Any Platform Loading , MD (...) Doses should be adjusted for renal insufficiency. Adverse effects are infrequent with oral administration but may include nausea, vomiting, diarrhea, headache, and rash. Topical antiviral drugs have only little value, and their use is discouraged. Evaluation of sex partners of patients with genital herpes is important. Prevention The best ways to avoid genital herpes are Abstaining from sexual contact (vaginal, anal, and oral sex) Being in a long-term mutually monogamous relationship with a partner

2013 Merck Manual (19th Edition)

1760. Toxic Shock Syndrome (TSS)

Because of worldwide vaccination, the current threat of a smallpox outbreak is most likely to come from which of the following? Bioterrorism Immunodeficiency Travel abroad Vaccination refusal NEWS & VIDEOS Mumps Outbreak Reported at Temple University FRIDAY, March 8, 2019 (HealthDay News) -- Ten confirmed cases of mumps, six probable cases, and a case under investigation have been reported at Temple University in Philadelphia. The university... Video Overview of Tuberculosis (TB) SOCIAL MEDIA Add (...) , which remains elevated) Hypotension (which can be refractory) A diffuse macular erythroderma Involvement of at least 2 other organ systems Staphylococcal TSS is likely to cause vomiting, diarrhea, myalgia, elevated CK, mucositis, hepatic damage, thrombocytopenia, and confusion. The staphylococcal TSS rash is more likely to desquamate, particularly on the palms and soles, between 3 and 7 days after onset. Streptococcal TSS commonly causes ARDS (in about 55% of patients), coagulopathy, and hepatic

2013 Merck Manual (19th Edition)

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