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, brucellosis). Expatriates returning from all three regions had higher PM for latent TB, amebiasis, and gastrointestinal infections (other than acute diarrhea) compared to non-expatriates. When the data were stratified by travel reason, business expatriates had higher PM for febrile systemic illness (malaria and dengue) and vaccine-preventable infections (hepatitis A), and volunteer expatriates had higher PM for parasitic infections. Expatriates overall had higher adjusted odds ratios for latent TB (...) and lower odds ratios for acute diarrhea and dermatologic illness.Ill returned expatriates differ from other travelers in travel characteristics and proportionate morbidity for specific diseases, based on the region of exposure and travel reason. They are more likely to present with more serious illness.
Profile of Travel-Associated Illness in Children, Zürich, Switzerland. The number of families traveling with their children to their country of origin and/or to tropical destinations has increased in Switzerland and includes a changing profile and multinational range of patients. Defining the profile of reported travel-associated illnesses will help to improve the prevention and treatment of such illnesses in children.This study includes children aged up to 16 years who sought medical advice (...) for a presumed travel-related illness at the emergency room of the University of Zürich Children's Hospital during the period July 2007 to December 2008.We analyzed data on 328 children (58.8% male, mean age: 4.62 y) who presented with travel-associated illness. Our analysis included 155 traditional (mainly tourist) travelers, 162 children who were visiting friends and relatives (VFR), and 11 immigrants. Some 11% were hospitalized. No deaths occurred. The main conditions recorded were diarrheal illness (39
, rickettsiosis, gastritis, peptic ulcers, esophagitis and gastroesophageal reflux disease, trauma and injuries, urinary tract infections, heart disease, and death. In contrast, acute diarrhea, upper respiratory tract infections, flu and flu-like illnesses, malaria, dengue, genital infections, sexually transmitted diseases, and schistosomiasis proportionate morbidities were lower among the older group.Older ill travelers are more likely to suffer from certain life-threatening diseases and would benefit from (...) Travel-Associated Illness in Older Adults (>60 y). Older individuals represent a substantial proportion of international travelers. Because of physiological changes and the increased probability of underlying medical conditions, older travelers might be at higher risk for at least some travel-associated diseases.With the aim of describing the epidemiology of travel-associated diseases in older adults, medical data were prospectively collected on ill international travelers presenting
travelers, and if these diagnoses were perceived to be changing in frequency.A majority of respondents (69%) provided both pre-travel counseling and post-travel evaluations, with significant variation in the numbers of such consultations. A majority of all respondents (61%) reported inadequate training in travel medicine during their fellowship years. However, a majority of recent graduates (55%) reported adequate preparation. Diagnoses of malaria, traveler'sdiarrhea, and typhoid fever were reported (...) Travel and tropical medicine practice among infectious disease practitioners. Infectious disease specialists who evaluate international travelers before or after their trips need skills to prevent, recognize, and treat an increasingly broad range of infectious diseases. Wide variation exists in training and percentage effort among providers of this care. In parallel, there may be variations in approach to pre-travel consultation and the types of travel-related illness encountered. Aggregate
workers, and more often medically counseled before their trip than pre-earthquake travelers. Work-related stress and upper respiratory tract infections were more frequent post-earthquake; acute diarrhea, dengue, and Plasmodium falciparum malaria were important contributors of morbidity both pre- and post-earthquake. These data highlight the importance of providing destination- and disaster-specific pre-travel counseling and post-travel evaluation and medical management to persons traveling (...) to or returning from a disaster location, and evaluations should include attention to the psychological wellbeing of these travelers. For travel to Haiti, focus should be on mosquito-borne illnesses (dengue and P. falciparum malaria) and travelers' diarrhea.
who had traveled abroad during the past 5 years (172 Crohn's disease, 105 ulcerative colitis) filled out the questionnaire. The majority (62%) answered that IBD limited their choice of travel destinations. Forty-three percent traveled to resource-limited destinations and 76% thereof obtained pretravel advice. Only 48% were prescribed an antibiotic for self-treatment in case of infectious diarrhea, and 23% were not protected against hepatitis A. Fecal urgency and incontinence were the main IBD (...) -related inconveniences. Thirty-two percent reported a new episode of diarrhea and 28% thereof attributed it to an enteric infection. In total, 15/277 (5%) consulted a foreign physician, of whom five were admitted to hospital. Fifty-four (19%) had a self-reported exacerbation of IBD within 2 months following travel and 24% thereof attributed it to the recent travel. The Mantel-Haenszel odds ratio for an exacerbation within a 2-month period after travel was 1.1 (95% confidence interval [CI] 0.7-1.8
Sabino S Baquero Margarita M eng Letter 2012 06 28 England J Med Microbiol 0224131 0022-2615 IM Adult Africa South of the Sahara Americas Asia Diarrhea epidemiology microbiology Enteropathogenic Escherichia coli isolation & purification Escherichia coli Infections classification epidemiology microbiology Female Hospital Units Humans Male Middle Aged Spain epidemiology Travel Tropical Medicine Young Adult 2012 6 30 6 0 2012 6 30 6 0 2012 12 10 6 0 ppublish 22745136 jmm.0.044461-0 10.1099/jmm.0.044461 (...) Diarrhoeagenic Escherichia coli Pathotypes in Travellers Attending a Tropical Medicine Unit in a Spanish Hospital. 22745136 2012 12 04 2012 09 17 1473-5644 61 Pt 10 2012 Oct Journal of medical microbiology J. Med. Microbiol. Diarrhoeagenic Escherichia coli pathotypes in travellers attending a tropical medicine unit in a Spanish hospital. 1485-7 10.1099/jmm.0.044461-0 Palmeiro Alejandra A Toro Carlos C Dhabi Ghizlane G Amor Aránzazu A Iglesias Nuria N Trevisi Patricia P Blanco Jorge J Puente
, sunburn and itch, and abdominal complaints like diarrhea were frequently reported ailments in both children and parents. Children in the age category 12 to 18 years showed a significantly higher ailment rate of 11.2 (6.8-14.1) than their parents.Skin problems and abdominal problems like diarrhea are frequently reported ailments in children and their parents and show a high tendency to recur during travel. The majority of these ailments are mild but occasionally interfere with planned activities (...) Travel-related morbidity in children: a prospective observational study. Scarce data are available on the occurrence of ailments and diseases in children during travel. We studied the characteristics and frequencies of ailments in children aged 0 to 18 years and their parents during traveling.A prospective observational study on ailments reported by children and parents traveling to (sub)tropical countries was conducted. The ailments were semi-quantitatively graded as mild, moderate, or severe
(MEDLINEPLUS) Traveling can increase your chances of getting sick. A long flight can increase your risk for deep vein thrombosis. Once you arrive, it takes time to adjust to the water, food, and air in another place. Water in developing countries can contain viruses, bacteria, and that cause stomach upset and diarrhea. Be safe by using only bottled or purified water for drinking, making ice cubes, and brushing your teeth. If you use tap water, boil it or use iodine tablets. can also be a risk. Eat only (...) Travel Preparation Travel Preparation Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Travel Preparation Travel Preparation Aka
. The incidence of pregnancy during travel was thus 0.93/1000 travelers. Thirty-three women traveled to East Asia, 8 to South and Central America, 5 to Africa. More than two thirds of women received pretravel vaccinations. Adherence to the World Health Organization recommendations regarding food and drink was high (87%) and travelers' diarrhea occurred in only 11% of women. Five of 22 women traveling to malarious areas had taken antimalarial prophylaxis. Six women required medical therapy during travel (...) Pregnancy course and outcome in women traveling to developing countries. The issue of travel to developing countries during pregnancy has not been sufficiently studied. The aim of this study is to investigate the rate, course, and outcome of pregnancies in women who traveled to developing countries while pregnant, or became pregnant during such travel.Women visiting two major travel clinics in Israel for consultation within the years 2004 to 2009, who were pregnant or declared an intention
The oral, live attenuated enterotoxigenic Escherichia coli vaccine ACE527 reduces the incidence and severity of diarrhea in a human challenge model of diarrheal disease. An oral, live attenuated, three-strain recombinant bacterial vaccine, ACE527, was demonstrated to generate strong immune responses to colonization factor and toxin antigens of enterotoxigenic Escherichia coli (ETEC) in human volunteers. The vaccine was safe and well tolerated at doses of up to 10(11) CFU, administered in each (...) of two doses given 21 days apart. These observations have now been extended in a phase 2b study with a total of 70 subjects. Fifty-six of these subjects were challenged 28 days after the second dose of vaccine with the highly virulent ETEC strain H10407 to obtain preliminary indicators of efficacy against disease and to support further development of the vaccine for both travelers and infants in countries where ETEC is endemic. The vaccine had a significant impact on intestinal colonization
Safety Study of Chimeric Vaccine to Prevent ETEC Diarrhea Safety Study of Chimeric Vaccine to Prevent ETEC Diarrhea - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Safety Study of Chimeric Vaccine (...) to Prevent ETEC Diarrhea The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT01644565 Recruitment Status : Unknown Verified October 2015 by U.S. Army Medical Research and Materiel Command. Recruitment status was: Active, not recruiting First Posted : July 19, 2012 Last Update Posted : November 2, 2015 Sponsor
Diarrhea in Children Diarrhea in Children Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Diarrhea in Children Diarrhea in Children (...) Aka: Diarrhea in Children , Pediatric Diarrhea , Pediatric Gastroenteritis , Gastroenteritis in Children , Acute Gastroenteritis in Children From Related Chapters II. Epidemiology U.S. Outpatient Visits: 1.5 Million per year U.S. Hospitalizations: 200,000 per year Deaths U.S.: 300 per year World: 2.5 Million per year (age under 5 years) Fifth leading cause of death in children worldwide) III. Definitions: Diarrhea See ral See Sudden increased stool frequency and looseness Three or more watery
Infectious Diarrhea Causes Aka: Infectious Diarrhea Causes From Related Chapters II. Causes: Bacteria Toxigenic (Enterotoxin binds : secretory, account for 80% of ) ( ) Most common in the returning traveler Contaminated water ingestion is the classic, historical example (shellfish ingestion can also occur) Associated with rice-water stools, severe dehydration, Ingestion of well or spring water (esp. in young children or immunocompromised patients) Most common , rapid onset within hours (esp. eggs (...) Infectious Diarrhea Causes Infectious Diarrhea Causes Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Infectious Diarrhea Causes
Chronic Diarrhea Chronic Diarrhea Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Chronic Diarrhea Chronic Diarrhea Aka: Chronic (...) Diarrhea From Related Chapters II. Definition Persistent >4 weeks III. Causes Large volume stools >1 L/day and not better over night or with g (diagnosis of exclusion) Small volume stools (<350 ml/day and better over night and with g) IV. History Age Young patients Functional bowel disorder ( ) Older patients pattern alternates with abuse Functional bowel disorder ( ) Intermittent Functional bowel disorder ( ) Malabsorption Persistent abuse Differentiating from or proximal colon involved Large stool
es (30-40% of episodes) (90% of non- l diarhea) and s (20-30% of episodes) Inflammatory Diarrhea from and s (most common ) Shiga-toxin producing (e.g. :H7, ) Causes 30% of infectious bloody Diarrhea Non-inflammatory Diarrhea from and s Bacillus cereus VII. Risk Factors See for systemic medical condition causes of Diarrhea See Recent travel to endemic area See Travel to a developing area is associated with a 25% chance of developing Diarrhea Those with Diarrhea in a developing area have an 80 (...) % chance of Bacterial Diarrhea Food associated illness See Associated with raw meats, poultry, fish, seafood, milk, rice Wilderness travel (or in developing country) See Hiking in wilderness areas (especially drinking from mountain streams) Consider , , Cryptospordium Day care exposure Consider , , , High-risk sexual behavior See Fecal-oral sexual contact: , , , Protozoa Receptive anal intercourse: , , , Antibiotic use within 6 months or recent hospitalizations See C. Difficile in unexplained Diarrhea
A randomized, double-blind, placebo-controlled study evaluating the efficacy and safety of rifaximin for the prevention of travelers' diarrhea in US military personnel deployed to Incirlik Air Base, Incirlik, Turkey. Infectious diarrhea is an important problem among travelers and deployed US military overseas causing substantial morbidity due to acute illness and may result in burdensome postinfectious sequelae.The nonsystemic antibiotic rifaximin was evaluated for prevention of travelers (...) ' diarrhea (TD) in a US military and civilian adult beneficiary population in a randomized, double-blind, placebo-controlled clinical trial. In all, 100 volunteers deployed to Incirlik Air Base, Turkey, received rifaximin 1,100 mg once daily or placebo for 2 weeks, and participants were followed daily for 2 weeks.In an intention to treat analysis (n = 95), TD (based on subjects meeting case definition or early treatment) developed in 6.3% (3 of 48) of the rifaximin group compared with 19.2% (9 of 47
The Prevalence of Norovirus in returning international travelers with diarrhea. There is a high incidence of diarrhea in traveling populations. Norovirus (NV) infection is a common cause of diarrhea and is associated with 7% of all diarrhea related deaths in the US. However, data on the overall prevalence of NV infection in traveling populations is limited. Furthermore, the prevalence of NV amongst travelers returning to Europe has not been reported. This study determined the prevalence of NV (...) among international travelers returning to Germany from over 50 destinations in and outside Europe.Stool samples of a total of 104 patients with a recent (< 14 days) history of international travel (55 male, mean age 37 yrs.) were tested for the presence of NV genogroup (GG) I and II infection using a sensitive and well established quantitative RT PCR method. 57 patients experienced diarrhea at the time of presentation at the Department of Infectious Diseases & Tropical Medicine. The remaining 47