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Topical Ointment

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21. Comparative Efficacy of Topical Pertmehrin, Crotamiton and Sulfur Ointment in Treatment of Scabies Full Text available with Trip Pro

Comparative Efficacy of Topical Pertmehrin, Crotamiton and Sulfur Ointment in Treatment of Scabies Scabies is an ectoparasitic infection, which occurs because of direct skin-to skin contact. The ideal treatment modality is still unclear and further research on this topic is warranted. The aim of the study was to compare the efficacy and safety of the topical scabicides: permethrin, crotamiton and sulfur ointment.Fifty four patients with diagnosed scabies were randomly divided into three (...) treatment groups. The first group received 5% permethrin cream twice with one week interval, the patients from the second group were given crotamiton lotion for two days twice with one week interval, while the third group received 10% sulfur ointment for two or three weeks. All patients were followed up at 1, 2 and 4 weeks intervals.At one-week follow up the cure rate was significantly higher at permethrin-treated group when compared to crotamiton group (P< 0.001) and sulfur group (P< 0.001). At the end

2017 Journal of Arthropod-Borne Diseases Controlled trial quality: uncertain

22. Topical Effects of Artemisia Absinthium Ointment and Liniment in Comparison with Piroxicam Gel in Patients with Knee Joint Osteoarthritis: A Randomized Double-Blind Controlled Trial Full Text available with Trip Pro

Topical Effects of Artemisia Absinthium Ointment and Liniment in Comparison with Piroxicam Gel in Patients with Knee Joint Osteoarthritis: A Randomized Double-Blind Controlled Trial Pain alleviation and improvement of functional status are the main objectives in the treatment of osteoarthritis. Artemisia absinthium (AA) was used traditionally in reducing pain and inflammation. The aim of the present study was to compare the effects of topical formulations of AA and piroxicam gel (PG) among (...) patients with knee osteoarthritis.In total, 90 outpatients aged 30-70 years with the diagnosis of primary osteoarthritis in at least one knee were enrolled in a randomized double-blind clinical trial. The patients referred to the Rheumatology Clinic at Shahid Beheshti Hospital in Hamadan province during 2012-2013. The patients were randomly assigned into three groups, 30 patients per group, and respectively received AA ointment (AAO) 3%, AA liniment (AAL) 3%, and PG; three times daily (TID) for 4 weeks

2017 Iranian journal of medical sciences Controlled trial quality: predicted high

23. Topical Sinecatechins, 10%, Ointment for Superficial Basal Cell Carcinoma: A Randomized Clinical Trial Full Text available with Trip Pro

Topical Sinecatechins, 10%, Ointment for Superficial Basal Cell Carcinoma: A Randomized Clinical Trial 28793140 2019 01 28 2019 01 28 2168-6084 153 10 2017 10 01 JAMA dermatology JAMA Dermatol Topical Sinecatechins, 10%, Ointment for Superficial Basal Cell Carcinoma: A Randomized Clinical Trial. 1061-1063 10.1001/jamadermatol.2017.2529 Kessels Janneke J Department of Dermatology, Maastricht University Medical Center, Maastricht, the Netherlands. GROW School for Developmental Biology (...) . Kelleners-Smeets Nicole W J NWJ Department of Dermatology, Maastricht University Medical Center, Maastricht, the Netherlands. GROW School for Developmental Biology and Oncology, Maastricht University, Maastricht, the Netherlands. eng Journal Article Randomized Controlled Trial Research Support, Non-U.S. Gov't United States JAMA Dermatol 101589530 2168-6068 0 Ointments 0 green tea extract polyphenone E 8R1V1STN48 Catechin AIM IM Administration, Topical Biopsy Camellia sinensis Carcinoma, Basal Cell

2017 JAMA dermatology Controlled trial quality: predicted high

24. Successful Management of Zoon’s Balanitis with Topical Mupirocin Ointment: A Case Report and Literature Review of Mupirocin-Responsive Balanitis Circumscripta Plasmacelluaris Full Text available with Trip Pro

Successful Management of Zoon’s Balanitis with Topical Mupirocin Ointment: A Case Report and Literature Review of Mupirocin-Responsive Balanitis Circumscripta Plasmacelluaris Zoon's balanitis, also referred to as balanitis circumscripta plasmacellularis (BCP), is an idiopathic, benign inflammatory condition of the glans penis and foreskin most often seen in elderly uncircumcised men. A patient with a biopsy-confirmed diagnosis of BCP who was successfully treated with topical mupirocin (...) ointment is described.The PubMed database was searched with the key words: bactroban, balanitis, cell, circumscripta, mupirocin, plasma, plasmacellularis, tacrolimus, Zoon. The papers generated by the search and their references were reviewed.Treatments for BCP have previously included circumcision and topical calcineurin inhibitors. Our patient with BCP rapidly resolved after initiating treatment with mupirocin 2% ointment.BCP is a benign dermatosis affecting the glans penis and foreskin. We confirm

2017 Dermatology and therapy

25. Topical Sirolimus Ointment for Cutaneous Angiofibromas in Subjects With Tuberous Sclerosis Complex

Topical Sirolimus Ointment for Cutaneous Angiofibromas in Subjects With Tuberous Sclerosis Complex Topical Sirolimus Ointment for Cutaneous Angiofibromas in Subjects With Tuberous Sclerosis Complex - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove (...) one or more studies before adding more. Topical Sirolimus Ointment for Cutaneous Angiofibromas in Subjects With Tuberous Sclerosis Complex The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03363763 Recruitment Status

2017 Clinical Trials

26. Study of RVT-501 Topical Ointment in Pediatric Patients With Atopic Dermatitis

Study of RVT-501 Topical Ointment in Pediatric Patients With Atopic Dermatitis Study of RVT-501 Topical Ointment in Pediatric Patients With Atopic Dermatitis - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more (...) . Study of RVT-501 Topical Ointment in Pediatric Patients With Atopic Dermatitis The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT03394677 Recruitment Status : Completed First Posted : January 9, 2018 Last Update Posted : July 19, 2018 Sponsor: Dermavant Sciences GmbH Information provided

2017 Clinical Trials

27. Reduction of postoperative pain and improvement of patients' comfort after Milligan-Morgan hemorrhoidectomy using topical application of vitamin E ointment. (Abstract)

Reduction of postoperative pain and improvement of patients' comfort after Milligan-Morgan hemorrhoidectomy using topical application of vitamin E ointment. 26715437 2017 04 03 2017 04 03 1432-1262 31 7 2016 Jul International journal of colorectal disease Int J Colorectal Dis Reduction of postoperative pain and improvement of patients' comfort after Milligan-Morgan hemorrhoidectomy using topical application of vitamin E ointment. 1371-2 10.1007/s00384-015-2483-4 Ruiz-Tovar Jaime J Department (...) Montiel M Department of Surgery, Coloproctology Unit, University Hospital King Juan Carlos, Gladiolo, s/n, 28933, Mostoles, Madrid, Spain. Garia-Olmo Damian D Department of Surgery, Coloproctology Unit, University Hospital King Juan Carlos, Gladiolo, s/n, 28933, Mostoles, Madrid, Spain. eng Letter Randomized Controlled Trial 2015 12 29 Germany Int J Colorectal Dis 8607899 0179-1958 1406-18-4 Vitamin E IM Administration, Topical Adult Aged Female Hemorrhoidectomy adverse effects Humans Length of Stay

2017 International journal of colorectal disease Controlled trial quality: uncertain

28. Safety and Efficacy of Diacerein 1% Ointment Topical Formulation Compared to Placebo for Subjects With Epidermolysis Bullosa Simplex (EBS)

Safety and Efficacy of Diacerein 1% Ointment Topical Formulation Compared to Placebo for Subjects With Epidermolysis Bullosa Simplex (EBS) Safety and Efficacy of Diacerein 1% Ointment Topical Formulation Compared to Placebo for Subjects With Epidermolysis Bullosa Simplex (EBS) - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study (...) Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Safety and Efficacy of Diacerein 1% Ointment Topical Formulation Compared to Placebo for Subjects With Epidermolysis Bullosa Simplex (EBS) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov

2017 Clinical Trials

29. Study of Topical SOR007 Ointment for Cutaneous Metastases

Study of Topical SOR007 Ointment for Cutaneous Metastases Study of Topical SOR007 Ointment for Cutaneous Metastases - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Study of Topical SOR007 Ointment (...) Biotest, Inc. Information provided by (Responsible Party): NanOlogy, LLC Study Details Study Description Go to Brief Summary: This study evaluates a topical nanoparticle paclitaxel ointment (SOR007) for the treatment of cutaneous metastases from non-melanoma cancer in adults. Three concentrations of SOR007 will be evaluated in dose-rising cohorts of three. An expanded cohort will treat additional subjects at the maximum tolerated dose. Condition or disease Intervention/treatment Phase Cutaneous

2017 Clinical Trials

30. The topical application of low-temperature argon plasma enhances the anti-inflammatory effect of Jaun-ointment on DNCB-induced NC/Nga mice. Full Text available with Trip Pro

The topical application of low-temperature argon plasma enhances the anti-inflammatory effect of Jaun-ointment on DNCB-induced NC/Nga mice. Jaun-ointment (JO), also known as Shiunko in Japan, is one of the most popular medicinal formulae used in Korean traditional medicine for the external treatment of skin wound and inflammatory skin conditions. Since JO is composed of crude mixture of two herbal extracts (radix of Lithospermum erythrorhizon Siebold & Zucc and Angelica gigas Nakai), those been (...) proved its anti-inflammatory activities in-vitro and in-vivo, JO has been expected as a good alternative treatment option for atopic dermatitis (AD). However, due to the lack of strategies for the penetrating methods of JO's various anti-inflammatory elements into the skin, an effective and safe transdermal drug delivery system needs to be determined. Here, low-temperature argon plasma (LTAP) was adopted as an ancillary partner of topically applied JO in a mice model of AD and the effectiveness

2017 BMC Complementary and Alternative Medicine

31. External genital and perianal warts: green tea (Camellia sinensis) leaf extract 10% ointment

summaries of product characteristics (SPCs), British national formulary (BNF) or the MHRA or NICE websites for up-to-date information. Summary Green tea (Camellia sinensis) leaf extract 10% ointment (Catephen) is a self-administered topical treatment for external genital and perianal warts. In 2 randomised controlled trials (RCTs) involving a total of 1005 adults, green tea leaf extract 10% ointment was 2-fold more effective than vehicle (placebo) ointment in terms of complete clearance of all baseline (...) with the person. There are 3 self-administered topical treatment options for external genital and perianal warts. All can cause local skin reactions. The maximum treatment duration for green tea leaf extract ointment is 16 weeks, with application 3 times a day. The maximum duration ranges from 4 to 5 weeks for podophyllotoxin preparations to 16 weeks for imiquimod 5% cream. These treatments require less frequent administration than green tea leaf extract ointment. These 3 treatments are available in a variety

2015 National Institute for Health and Clinical Excellence - Advice

32. Topical Ointment

Topical Ointment Topical Ointment Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Topical Ointment Topical Ointment Aka: Topical (...) ) May occlude s more than less occlusive (such as s) VI. Pharmacology ointments are more potent than creams Ointment vehicle holds steroid to skin surface Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term "Topical Ointment." Click on the image (or right click) to open the source website in a new browser window. Related Studies (from Trip Database) Related Topics in Pharmacology About FPnotebook.com is a rapid access, point-of-care

2018 FP Notebook

33. Comparison of Lindioil (Indigo Naturalis Oil Extract) Ointment to Protopic® Ointment 0.1% in Treating Atopic Dermatitis

by itchiness. Topical corticosteroids are typically used to treat AD. However, many patients have concerns about the safety of long-term use, and seek alternative therapies such as traditional Chinese medicine (TCM). In TCM, indigo naturalis has been used to treat various infectious and inflammatory skin diseases for hundreds of years. The investigate also found that the results of indigo naturalis ointment treatment in other trial were comparable to the results of calcineurin inhibitor (such as Tacrolimus (...) of Lindioil (Indigo Naturalis Oil Extract) Ointment to Protopic® (Tacrolimus 0.1%) Ointment in Treating Atopic Dermatitis: A Randomized, Evaluator-blind, Crossover, Active-Controlled Trial Estimated Study Start Date : April 1, 2019 Estimated Primary Completion Date : July 31, 2021 Estimated Study Completion Date : July 31, 2021 Resource links provided by the National Library of Medicine related topics: related topics: available for: Arms and Interventions Go to Arm Intervention/treatment Experimental

2018 Clinical Trials

34. Study To Assess Local Tolerability of Crisaborole 2% Ointment and Vehicle Ointment In Healthy Participants Using Subject-reported Assessments and Objective Measurements

applied to sensitive skin locations on left side of body Drug: Within-Subject Active vs Placebo Topical Applications Crisaborole 2% ointment (right side) and Placebo vehicle ointment (left side) Group B (Crisaborole LEFT SIDE / Vehicle RIGHT SIDE) Crisaborole placebo vehicle ointment applied to 7 sensitive skin sites on right side of body. Crisaborole ointment 2% applied to 7 sensitive skin locations on left side of body Drug: Within-Subject Active vs. Placebo Topical Applications Crisaborole 2 (...) Study To Assess Local Tolerability of Crisaborole 2% Ointment and Vehicle Ointment In Healthy Participants Using Subject-reported Assessments and Objective Measurements Study To Assess Local Tolerability of Crisaborole 2% Ointment and Vehicle Ointment In Healthy Participants Using Subject-reported Assessments and Objective Measurements - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search

2018 Clinical Trials

35. Phase 2 clinical study of delgocitinib ointment in pediatric patients with atopic dermatitis Full Text available with Trip Pro

Phase 2 clinical study of delgocitinib ointment in pediatric patients with atopic dermatitis Topical delgocitinib (JTE-052), a novel Janus kinase inhibitor, had been shown to be clinically effective in adults with atopic dermatitis (AD). However, the efficacy of topical delgocitinib in pediatric patients with AD remained unclear.We sought to evaluate the efficacy and safety of delgocitinib ointment in pediatric patients with AD.In this phase 2 clinical study (JapicCTI-173553) Japanese patients (...) aged 2 through 15 years with AD were randomized in a 1:1:1 ratio to receive 0.25% or 0.5% delgocitinib ointment or vehicle ointment twice daily for 4 weeks. The primary efficacy end point was the percentage change from baseline in the modified Eczema Area and Severity Index score at the end of treatment (EOT).At EOT, modified Eczema Area and Severity Index scores in both delgocitinib groups were significantly reduced compared with that in the vehicle group. The least-squares mean percentage change

2019 EvidenceUpdates

36. Are Topical Nonsteroidal Anti-Inflammatory Drugs Useful for Analgesia in Patients With Traumatic Corneal Abrasions? Full Text available with Trip Pro

, the frequency of healing at 24 and 48 hours after injury, whether the use of concurrent topical antibiotics (drops or ointments) with additional lubricating effects reduced pain, and the complications of corneal abrasions through the use of topical nonsteroidal anti-inflammatory drugs versus the control groups. Data Extraction and Synthesis Two reviewers independently assessed the articles for eligibility, performed data extraction, assessed risk of bias by the Cochrane Risk of Bias Tool, x 1 Higgins, J.P (...) ointment versus topical polyvinyl alcohol and an ophthalmic antibiotic ointment, x 9 Brahma, A.K., Shah, S., Hillier, V.F. et al. Topical analgesia for superficial corneal injuries. J Accid Emerg Med . 1996 ; 13 : 186–188 | | a topical nonsteroidal anti-inflammatory drug versus topical polyvinyl alcohol, x 10 Goyal, R., Shankar, J., Fone, D.L. et al. Randomised controlled trial of ketorolac in the management of corneal abrasions. Acta Ophthalmol Scand . 2001 ; 79 : 177–179 | | | and a topical

2019 Annals of Emergency Medicine Systematic Review Snapshots

37. Topical Photodynamic therapy

Topical Photodynamic therapy EDF Guidelines Office to Professor Dr. Nast: Martin Dittmann, Klinik für Dermatologie, Venerologie und Allergologie, Campus Charité Mitte, Charité – Universitätsmedizin Berlin, Charitéplatz 1, 10117 Berlin, Germany phone: +49 30 450 618 313, fax: +49 30 450 518 977, e-mail: martin.dittmann@charite.de European Dermatology Forum Guidelines on Topical Photodynamic Therapy Updated version – 2019 Expiry date: 08/2022 European Dermatology Forum Guidelines on Topical (...) that readers could perceive to have influenced, or that give the appearance of potentially influencing, what you wrote in the submitted work? No Disclaimer These updated guidelines consider all current and emerging indications for the use of topical photodynamic therapy (PDT) in Dermatology. In addition to undertaking an updated systematic literature review, they include evidence reviewed in previous therapy specific PDT guidelines published in 2007 1 , 2013 2,3 ,and 2018 4 as well as disease-specific

2019 European Dermatology Forum

38. Dressings and topical agents for treating pressure ulcers. Full Text available with Trip Pro

Dressings and topical agents for treating pressure ulcers. Pressure ulcers, also known as bedsores, decubitus ulcers and pressure injuries, are localised areas of injury to the skin or the underlying tissue, or both. Dressings are widely used to treat pressure ulcers and promote healing, and there are many options to choose from including alginate, hydrocolloid and protease-modulating dressings. Topical agents have also been used as alternatives to dressings in order to promote healing.A clear (...) and current overview of all the evidence is required to facilitate decision-making regarding the use of dressings or topical agents for the treatment of pressure ulcers. Such a review would ideally help people with pressure ulcers and health professionals assess the best treatment options. This review is a network meta-analysis (NMA) which assesses the probability of complete ulcer healing associated with alternative dressings and topical agents.To assess the effects of dressings and topical agents

2017 Cochrane

39. Topical antimicrobial agents for treating foot ulcers in people with diabetes. Full Text available with Trip Pro

also searched clinical trials registries for ongoing and unpublished studies, and checked reference lists to identify additional studies. We used no restrictions with respect to language, date of publication, or study setting.We included randomised controlled trials conducted in any setting (inpatient or outpatient) that evaluated topical treatment with any type of solid or liquid (e.g., cream, gel, ointment) antimicrobial agent, including antiseptics, antibiotics, and antimicrobial dressings (...) Topical antimicrobial agents for treating foot ulcers in people with diabetes. People with diabetes are at high risk for developing foot ulcers, which often become infected. These wounds, especially when infected, cause substantial morbidity. Wound treatments should aim to alleviate symptoms, promote healing, and avoid adverse outcomes, especially lower extremity amputation. Topical antimicrobial therapy has been used on diabetic foot ulcers, either as a treatment for clinically infected wounds

2017 Cochrane

40. Topical phenytoin for treating pressure ulcers. Full Text available with Trip Pro

including dressings, ointments and creams such as bacitracin, silver sulphadiazine, neomycin, and phenytoin. Phenytoin is a drug more commonly used in the treatment of epilepsy, but may play an important role in accelerating ulcer healing.To assess the effects of topical phenytoin on the rate of healing of pressure ulcers of any grade, in any care setting.In September 2016, we searched the following electronic databases to identify relevant randomized clinical trials: the Cochrane Wounds Specialised (...) : hydrocolloid dressings, triple antibiotic ointment and simple dressings. In the three RCTs, 79% of participants had grade II ulcers, and 21% of participants had grade I ulcers; no participants had grade III or IV ulcers. Two RCTs had a high risk of bias overall and the other RCT was at unclear risk of bias due to poor reporting. Two RCTs had three intervention arms and the other had two intervention arms.Two studies compared topical phenytoin with hydrocolloid dressing (84 participants analysed

2017 Cochrane

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