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Topical NSAID

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61. Study to Determine the Safety and the Efficacy of Fasinumab Compared to Placebo and Nonsteroidal Anti-inflammatory Drugs (NSAIDs) for Treatment of Adults With Pain From Osteoarthritis of the Knee or Hip

by the National Library of Medicine related topics: related topics: Arms and Interventions Go to Arm Intervention/treatment Experimental: Dosing regimen 1 Drug: Fasinumab Solution for injection in pre-filled syringe Other Names: REGN475 MT-5547 Drug: Matching placebo Fasinumab-matching placebo (solution for injection in pre-filled syringe); NSAID-matching placebo (capsule) Experimental: Dosing regimen 2 Other: Diclofenac NSAID active comparator (capsule) Other Name: ZORVOLEX Drug: Matching placebo Fasinumab (...) Study to Determine the Safety and the Efficacy of Fasinumab Compared to Placebo and Nonsteroidal Anti-inflammatory Drugs (NSAIDs) for Treatment of Adults With Pain From Osteoarthritis of the Knee or Hip Study to Determine the Safety and the Efficacy of Fasinumab Compared to Placebo and Nonsteroidal Anti-inflammatory Drugs (NSAIDs) for Treatment of Adults With Pain From Osteoarthritis of the Knee or Hip - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer

2017 Clinical Trials

62. Characterization of Non-Steroidal Anti-Inflammatory Drug (NSAID) Intake in Rheumatoid Arthritis (RA) Participants on Tocilizumab (RoACTEMRA®) Treatment

by the National Library of Medicine related topics: related topics: available for: Groups and Cohorts Go to Group/Cohort Intervention/treatment Participants With RA Participants with RA who are being treated with tocilizumab and NSAIDs will be observed for approximately 6 months to evaluate the quantitative pattern of NSAID use and the impact of treatment with tocilizumab on NSAID use. Drug: Tocilizumab Tocilizumab (SC or IV) will be prescribed according to local clinical practice and the SPC. Other Name (...) Characterization of Non-Steroidal Anti-Inflammatory Drug (NSAID) Intake in Rheumatoid Arthritis (RA) Participants on Tocilizumab (RoACTEMRA®) Treatment Characterization of Non-Steroidal Anti-Inflammatory Drug (NSAID) Intake in Rheumatoid Arthritis (RA) Participants on Tocilizumab (RoACTEMRA®) Treatment - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved

2017 Clinical Trials

63. Safety of topical non-steroidal anti-inflammatory drugs (NSAIDS) for osteoarthritis: a systematic review with meta-analysis

Safety of topical non-steroidal anti-inflammatory drugs (NSAIDS) for osteoarthritis: a systematic review with meta-analysis Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email salutation (e.g. "Dr Smith" or "Joanne") for correspondence

2017 PROSPERO

64. Side effects of topical Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) in osteoarthritis: a systematic review and meta-analysis of randomised, placebo-controlled Trials

Side effects of topical Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) in osteoarthritis: a systematic review and meta-analysis of randomised, placebo-controlled Trials Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email salutation

2017 PROSPERO

65. Topical interferon alpha 2b in the treatment of refractory pseudophakic cystoid macular edema (PubMed)

Topical interferon alpha 2b in the treatment of refractory pseudophakic cystoid macular edema To report the efficacy and safety of interferon alpha 2b in the treatment of pseudophakic cystoid macular edema resistant to conventional therapy.A 64-year-old patient presented with pseudophakic cystoid macular edema in her left eye, which developed two months after an uncomplicated cataract surgery and was resistant to multiple topical NSAIDs and multiple intravitreal bevacizumab injections over (...) the course of nine months. She also developed side effects to oral acetazolamide and intravitreal triamcinolone injection; a skin rash and a rise in intraocular pressure (34 mmHg), respectively. She was subsequently started on topical interferon alpha 2b (1 MIU/ml) four times a day nine months after developing pseudophakic cystoid macular edema. Cystoid macular edema improved significantly in four weeks and completely resolved after twelve weeks. Her vision improved from 20/100 before starting treatment

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2018 American journal of ophthalmology case reports

66. Topical non-steroidal anti-inflammatory agents for diabetic cystoid macular oedema. (PubMed)

spontaneously, or fluctuate for months, before causing loss of vision. If left untreated or undiagnosed, progression of CMO may lead to permanent visual loss.It has been noted that patients with diabetic retinopathy have elevated inflammatory markers, and therefore it is likely that inflammation aids in the progression of vascular disease in these patients. Several topical non-steroidal anti-inflammatory drugs (NSAIDs) such as ketorolac 0.5%, bromfenac 0.09%, and nepafenac 0.1%, have therefore also been (...) used topically to treat chronic diabetic CMO. Hence this review was conducted to find out the effects of topical NSAIDs in diabetic CMO.To assess the effects of topical non-steroidal anti-inflammatory drugs (NSAIDs) for diabetic cystoid macular oedema (CMO).We searched CENTRAL (which contains the Cochrane Eyes and Vision Group Trials Register) (2014, Issue 12), Ovid MEDLINE, Ovid MEDLINE In-Process and Other Non-Indexed Citations, Ovid MEDLINE Daily, Ovid OLDMEDLINE (January 1946 to January 2015

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2015 Cochrane

67. NSAIDs and other complementary treatments for episodic migraine prevention in adults

NSAIDs and other complementary treatments for episodic migraine prevention in adults Evidence-based guideline update: NSAIDs and other complementary treatments for episodic migraine prevention in adults: [RETIRED] | Neurology Advertisement Search for this keyword Main menu User menu Search Search for this keyword The most widely read and highly cited peer-reviewed neurology journal Share April 24, 2012 ; 78 (17) Special Articles Evidence-based guideline update: NSAIDs and other complementary (...) Center, Dallas, TX; Mayo Clinic (D.D.), Scottsdale, AZ; New York University School of Medicine (C.A.), Albany; and Elmendorf Air Force Base (E.A.), AK. Evidence-based guideline update: NSAIDs and other complementary treatments for episodic migraine prevention in adults: [RETIRED] S. Holland , S.D. Silberstein , F. Freitag , D.W. Dodick , C. Argoff , E. Ashman Neurology Apr 2012, 78 (17) 1346-1353; DOI: 10.1212/WNL.0b013e3182535d0c Citation Manager Formats Make Comment See Comments Downloads 42567

2012 American Academy of Neurology

68. Compounded Diclofenac Cream for Topical Anti-Inflammatory Treatment

). Available from: http://www.ncbi.nlm.nih.gov/books/NBK53955/ Systematic Reviews and Meta-analyses – Topical Diclofenac 3. BMJ Clinical Evidence [Internet]. London: BMJ Publishing Group Limited. Non-steroidal anti-inflammatory drugs (NSAIDs) (topical); 2014 Oct 14 [cited 2015 Apr 28]. Available from: http://clinicalevidence.bmj.com/x/systematic-review/0812/intervention/sr- 0812-i14.html 4. Derry S, Moore RA, Rabbie R. Topical NSAIDs for chronic musculoskeletal pain in adults. Cochrane Database Syst Rev (...) [Internet]. Edinburgh: SIGN; 2013 Dec. [cited 2015 Apr 28]. (SIGN publication no. 136). Available from: http://www.sign.ac.uk/pdf/SIGN136.pdf See: 5.2.4 Topical NSAIDs 11. Treatment of osteoarthritis of the knee: evidence-based guideline [Internet]. 2 nd edition. Rosemont (IL): American Academy of Orthopaedic Surgeons; 2013 May 18. [cited 2015 Apr 28]. Available from: http://www.aaos.org/research/guidelines/TreatmentofOsteoarthritisoftheKneeGuideline.pdf See: Recommendation 7A, page 342 12. Hand, wrist

2015 Canadian Agency for Drugs and Technologies in Health - Rapid Review

69. Do NSAIDS or Executing Exercise Decrease Local Erythema, Site Swelling & Pain After INoculation

After INoculation: the NEED LESS PAIN Study" Study Start Date : September 2016 Actual Primary Completion Date : December 2018 Actual Study Completion Date : December 2018 Resource links provided by the National Library of Medicine related topics: available for: Arms and Interventions Go to Arm Intervention/treatment Experimental: Ibuprofen Randomized and double blinded study participants assigned to Group A intervention will receive an oral NSAID of ibuprofen 800 mgs three times a day for 48 hours (...) medical exclusion for ibuprofen. Have a history of stroke or coronary artery disease, such as uncontrolled high blood pressure or abnormal heart beat. Has taken any topical or oral pain medications from the following medication classes in the past 24 hours prior to the start of the study: oral acetaminophen, opioids, tramadol, nonsteroidal anti-inflammatory drug (NSAID) or acetylsalicylic acid (ASA) or topical pain relievers or counterirritants of menthol, methyl salicylate, camphor menthols

2016 Clinical Trials

70. A Randomized, Double-blind, Placebo-controlled Multicenter Study of Secukinumab (AIN457) to Examine the Clinical Efficacy and the Nonsteroidal Anti-inflammatory Drug (NSAID)-Sparing Effect of Secukinumab Over 16 Weeks in Patients With Ankylosing Spondylit

Study Start Date : May 31, 2016 Estimated Primary Completion Date : July 1, 2019 Estimated Study Completion Date : July 1, 2019 Resource links provided by the National Library of Medicine related topics: related topics: available for: resources: Arms and Interventions Go to Arm Intervention/treatment Experimental: AIN457/Secukinumab - delayed tapering Secukinumab 150 mg s.c. from week 0 with NSAID tapering allowed from week 4 (delayed tapering) Biological: AIN457/Secukinumab Induction: 4x 150 mg (...) A Randomized, Double-blind, Placebo-controlled Multicenter Study of Secukinumab (AIN457) to Examine the Clinical Efficacy and the Nonsteroidal Anti-inflammatory Drug (NSAID)-Sparing Effect of Secukinumab Over 16 Weeks in Patients With Ankylosing Spondylit A Randomized, Double-blind, Placebo-controlled Multicenter Study of Secukinumab (AIN457) to Examine the Clinical Efficacy and the Nonsteroidal Anti-inflammatory Drug (NSAID)-Sparing Effect of Secukinumab Over 16 Weeks in Patients

2016 Clinical Trials

71. NSAID Treatment of Patients With Osteoarthritis

Purpose: Diagnostic Official Title: BEVAR: Patientspecifik Behandling Ved Artrose - Et "Proof-of-concept"- Kvalitetssikringsstudie Study Start Date : January 2016 Actual Primary Completion Date : January 2018 Actual Study Completion Date : February 1, 2018 Resource links provided by the National Library of Medicine related topics: related topics: Arms and Interventions Go to Arm Intervention/treatment Experimental: NSAID treatment 8 weeks of NSAID treatment Drug: NSAID NSAIDs are among the most common (...) NSAID Treatment of Patients With Osteoarthritis NSAID Treatment of Patients With Osteoarthritis - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. NSAID Treatment of Patients With Osteoarthritis The safety

2016 Clinical Trials

72. Proof-of-concept Study of NSAID Hydrogel Patch in Treatment of Acute Pain

Proof-of-concept Study of NSAID Hydrogel Patch in Treatment of Acute Pain Proof-of-concept Study of NSAID Hydrogel Patch in Treatment of Acute Pain - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Proof (...) -of-concept Study of NSAID Hydrogel Patch in Treatment of Acute Pain The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02729207 Recruitment Status : Unknown Verified March 2016 by Teikoku Seiyaku Co., Ltd.. Recruitment status was: Not yet recruiting First Posted : April 6, 2016 Last Update Posted : April 6

2016 Clinical Trials

73. Effects of a Cyclic NSAID Regimen on Levels of GCF PGE-E2 and IL-1beta

Effects of a Cyclic NSAID Regimen on Levels of GCF PGE-E2 and IL-1beta Effects of a Cyclic NSAID Regimen on Levels of GCF PGE-E2 and IL-1beta - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Effects (...) of a Cyclic NSAID Regimen on Levels of GCF PGE-E2 and IL-1beta The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02658799 Recruitment Status : Completed First Posted : January 20, 2016 Last Update Posted : January 20, 2016 Sponsor: Baskent University Information provided by (Responsible Party): Nilgün Özlem

2016 Clinical Trials

74. Post-op Acetaminophen vs NSAID Use on Lumbar Spinal Fusion Outcomes

-Inflammatory Drug (NSAID) Use on Lumbar Spinal Fusion Outcomes Study Start Date : March 2016 Estimated Primary Completion Date : August 2019 Estimated Study Completion Date : August 2021 Resource links provided by the National Library of Medicine related topics: available for: Arms and Interventions Go to Arm Intervention/treatment Placebo Comparator: Intravenous (IV) Placebo IV Placebo arm Drug: Placebo Intravenous Normal Saline every 6 hours for 48 hours in addition to patient-controlled analgesia (...) Post-op Acetaminophen vs NSAID Use on Lumbar Spinal Fusion Outcomes Post-op Acetaminophen vs NSAID Use on Lumbar Spinal Fusion Outcomes - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Post-op Acetaminophen

2016 Clinical Trials

75. Impact of a Free Distribution of Paracetamol to Osteoarthritic Patients on Non-steroidal Anti-inflammatory Drugs (NSAID) and Proton Pump Inhibitors (PPI) Prescription

Impact of a Free Distribution of Paracetamol to Osteoarthritic Patients on Non-steroidal Anti-inflammatory Drugs (NSAID) and Proton Pump Inhibitors (PPI) Prescription Impact of a Free Distribution of Paracetamol to Osteoarthritic Patients on Non-steroidal Anti-inflammatory Drugs (NSAID) and Proton Pump Inhibitors (PPI) Prescription - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms (...) x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Impact of a Free Distribution of Paracetamol to Osteoarthritic Patients on Non-steroidal Anti-inflammatory Drugs (NSAID) and Proton Pump Inhibitors (PPI) Prescription The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been

2016 Clinical Trials

76. NSAID vs. Narcotics

NSAID vs. Narcotics NSAID vs. Narcotics - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. NSAID vs. Narcotics The safety and scientific validity of this study is the responsibility of the study sponsor (...) . The study will compare post-operative pain scores and narcotic consumption between two groups of patients - one cohort will receive ibuprofen (Motrin) and Percocet (to be used as needed) while the other cohort will receive only Percocet. Both pain management options are considered to be standard of care. The primary objective of the study is to compare patients' reported pain and narcotic use following meniscectomy, and determine if NSAIDs can provide adequate pain relief. Condition or disease

2016 Clinical Trials

77. NSAID Use in Postpartum Hypertensive Women

NSAID Use in Postpartum Hypertensive Women NSAID Use in Postpartum Hypertensive Women - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. NSAID Use in Postpartum Hypertensive Women The safety and scientific (...) ): Jennifer Goldkamp, MD, St. Louis University Study Details Study Description Go to Brief Summary: Women who have the diagnosis of hypertension (pre-pregnancy and pregnancy induced) and deliver an infant via vaginal delivery will be placed into two groups in the postpartum period. One group will receive Ibuprofen for pain control and the other group will be given Tylenol. Blood pressures during the postpartum period will then be collected and compared in order to see if NSAIDs use increases blood

2016 Clinical Trials

78. NSAIDs Added to Anti-TNF Therapy Versus Anti-TNF Therapy Alone on Progression of Structural Damage in Ankylosing Spondylitis

NSAIDs Added to Anti-TNF Therapy Versus Anti-TNF Therapy Alone on Progression of Structural Damage in Ankylosing Spondylitis NSAIDs Added to Anti-TNF Therapy Versus Anti-TNF Therapy Alone on Progression of Structural Damage in Ankylosing Spondylitis - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached (...) the maximum number of saved studies (100). Please remove one or more studies before adding more. NSAIDs Added to Anti-TNF Therapy Versus Anti-TNF Therapy Alone on Progression of Structural Damage in Ankylosing Spondylitis (CONSUL) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02758782 Recruitment Status

2016 Clinical Trials

79. Exposure to NSAIDs (Non Steroidal Anti-Inflammatory Drugs) and Severity of Community-acquired Bacterial Infections

Exposure to NSAIDs (Non Steroidal Anti-Inflammatory Drugs) and Severity of Community-acquired Bacterial Infections Exposure to NSAIDs (Non Steroidal Anti-Inflammatory Drugs) and Severity of Community-acquired Bacterial Infections - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number (...) of saved studies (100). Please remove one or more studies before adding more. Exposure to NSAIDs (Non Steroidal Anti-Inflammatory Drugs) and Severity of Community-acquired Bacterial Infections (ANAIG) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details

2016 Clinical Trials

80. The dangers of NSAIDs: look both ways (PubMed)

The dangers of NSAIDs: look both ways 27033477 2017 05 19 2018 11 13 1478-5242 66 645 2016 Apr The British journal of general practice : the journal of the Royal College of General Practitioners Br J Gen Pract The dangers of NSAIDs: look both ways. 172-3 10.3399/bjgp16X684433 Davis Abigail A Centre for Primary Care and Public Health, Queen Mary University of London, London. Robson John J Centre for Primary Care and Public Health, Queen Mary University of London, London. eng Editorial England Br (...) J Gen Pract 9005323 0960-1643 0 Anti-Inflammatory Agents, Non-Steroidal IM Anti-Inflammatory Agents, Non-Steroidal administration & dosage adverse effects Contraindications Decision Making Drug Interactions General Practice methods Hospitalization statistics & numerical data Humans Musculoskeletal Pain diagnosis drug therapy Pain Management Patient Safety standards Practice Guidelines as Topic Practice Patterns, Physicians' statistics & numerical data Risk Assessment 2016 4 2 6 0 2016 4 2 6 0

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2016 The British Journal of General Practice

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