How to Trip Rapid Review

Step 1: Select articles relevant to your search (remember the system is only optimised for single intervention studies)

Step 2: press

Step 3: review the result, and maybe amend the or if you know better! If we're unsure of the overall sentiment of the trial we will display the conclusion under the article title. We then require you to tell us what the correct sentiment is.

27,777 results for

Topical Corticosteroid

by
...
Latest & greatest
Alerts

Export results

Use check boxes to select individual results below

SmartSearch available

Trip's SmartSearch engine has discovered connected searches & results. Click to show

101. Topical Corticosteroid App

Topical Corticosteroid App Topical Corticosteroid App - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Topical Corticosteroid App The safety and scientific validity of this study is the responsibility (...) the effectiveness of a mobile application to assist in the prescription of topical corticosteroids (TCS), focusing on best fit choices of potency, vehicle and volume. The mobile application will be developed from the results obtained in a systematic literature review and quality assessment of clinical practice guidelines for topical corticosteroid use. The quality of the guidelines will be assessed using the AGREE II tool. After the app user enters in information concerning patients' rash location and desired

2016 Clinical Trials

102. Differences in therapeutic effects of topically applied corticosteroid and tacrolimus on atopic dermatitis-like symptoms in NC/Nga mice. (PubMed)

Differences in therapeutic effects of topically applied corticosteroid and tacrolimus on atopic dermatitis-like symptoms in NC/Nga mice. Topical corticosteroid and calcineurin inhibitor have similar therapeutic benefits in atopic dermatitis (AD), but the differences in therapeutic mechanisms of action of these agents against AD symptoms are not fully understood.This study was performed to examine the different effects of topical betamethasone valerate (BMV), clobetasol propionate (CBP (...) the strongest effect. CBP significantly reduced epidermal thickness compared with Vas and NT. There were no significant differences in the numbers of interleukin-31-immunoreactive cells and mast cells, or in expression of epidermal thymic stromal lymphopoietin among all five groups.The therapeutic potency of TAC against AD-like symptoms, including pruritus, is equal to that of the corticosteroid CBP. Epidermal innervation of sensory nerves itself might not be related to the therapeutic effects of topical

2016 Journal of dermatological science

103. Topical corticosteroids application in the evening is more effective than in the morning in psoriasis: results of a prospective comparative study. (PubMed)

Topical corticosteroids application in the evening is more effective than in the morning in psoriasis: results of a prospective comparative study. 27790782 2017 04 27 1468-3083 31 5 2017 May Journal of the European Academy of Dermatology and Venereology : JEADV J Eur Acad Dermatol Venereol Topical corticosteroids application in the evening is more effective than in the morning in psoriasis: results of a prospective comparative study. e263-e264 10.1111/jdv.14027 Nguyen S S Department

2016 Journal of the European Academy of Dermatology and Venereology

104. Carers' views of topical-corticosteroid use in childhood eczema: a qualitative study of online discussion forums. (PubMed)

Carers' views of topical-corticosteroid use in childhood eczema: a qualitative study of online discussion forums. Childhood eczema is very common and can have substantial impact on quality of life. One of the main treatments is topical corticosteroids, but these are often underused by parents and carers for reasons that include concerns about safety.To explore understandings and concerns about topical corticosteroids among parents and carers of children with eczema who had posted messages (...) in online forums.A qualitative study of messages and their resultant discussions about topical corticosteroids for childhood eczema posted by parents and carers on two U.K.-based discussion forums.Ninety-five forum users involved in 27 discussions relating to topical corticosteroid use in childhood eczema were identified dating from 2003 to 2015. Analysis of discussions highlighted three themes: (i) diverse beliefs about the use of topical corticosteroids; (ii) uncertainty and confusion about using

Full Text available with Trip Pro

2016 British Journal of Dermatology

105. Descemet's Membrane Endothelial Keratoplasty: Risk of Immunologic Rejection Episodes after Discontinuing Topical Corticosteroids. (PubMed)

Descemet's Membrane Endothelial Keratoplasty: Risk of Immunologic Rejection Episodes after Discontinuing Topical Corticosteroids. To assess the risk of immunologic rejection episodes if topical corticosteroids are discontinued 1 year after Descemet's membrane endothelial keratoplasty (DMEK) compared with continued once-per-day use.Prospective, longitudinal, parallel-group study.A total of 400 eyes of 259 DMEK recipients, aged 23 to 90 years.Patients were enrolled 1 year after DMEK and allowed (...) to choose whether to stop or continue once-daily topical corticosteroids to maximize compliance. Fellow eyes were eligible for enrollment because the donor grafts were independent. Participants were examined at 1, 3, 6, and 12 months during the second year after DMEK. Results were assessed using Kaplan-Meier survival analysis.Incidence of immunologic rejection episodes.Steroids were discontinued in 277 eyes (no steroid group) and continued once per day in 123 eyes (steroid group). The subject

2016 Ophthalmology

106. Medical adherence to topical corticosteroid preparations prescribed for psoriasis: A systematic review. (PubMed)

Medical adherence to topical corticosteroid preparations prescribed for psoriasis: A systematic review. Topical corticosteroids and corticosteroid combinations are the principal treatments in psoriasis. The aim of this study was to investigate published literature dealing with medical adherence to topical corticosteroid or corticosteroid combinations in patients with psoriasis.Systematic electronic searches in English language literature were done until September 2015 without publication date (...) determinants of nonadherence were found. One designed intervention consisted of a disease management program, which improved adherence in the study period. Overall, the studies included were heterogeneous in design and had a high risk of bias.To improve health outcome in topical treatment of psoriasis, further studies should be conducted addressing determinants of nonadherence and test interventions to improve adherence. Validated measurements of medical nonadherence, prescription registers, or medication

2016 The Journal of dermatological treatment

107. Monitoring of topical corticosteroid phobia in a population of parents with children with atopic dermatitis using the TOPICOP<sup>®</sup> scale: prevalence, risk factors and the impact of therapeutic patient education. (PubMed)

Monitoring of topical corticosteroid phobia in a population of parents with children with atopic dermatitis using the TOPICOP® scale: prevalence, risk factors and the impact of therapeutic patient education. 27608366 2017 03 15 1468-3083 31 3 2017 Mar Journal of the European Academy of Dermatology and Venereology : JEADV J Eur Acad Dermatol Venereol Monitoring of topical corticosteroid phobia in a population of parents with children with atopic dermatitis using the TOPICOP ® scale

2016 Journal of the European Academy of Dermatology and Venereology

108. The effects of oral and topical corticosteroid in rabbit corneas. (PubMed)

The effects of oral and topical corticosteroid in rabbit corneas. To determine the most effective route of administration of corticosteroids in the treatment of ocular surface disease, by characterizing the difference between oral prednisolone and topical dexamethasone administration using an animal model.Pharmacokinetic analyses determined the corticosteroid concentrations in the normal ocular tissues of rabbits after oral or topical administration of corticosteroids using LC-MS/MS. In wound (...) observed between orally and topically administered groups. Pharmacokinetic analyses showed that the distribution of dexamethasone after topical administration was superior to that after oral administration in the cornea. In contrast, both concentrations of corticosteroid applied topically and orally were similar with regards to AUCs (area under the concentration-time curve) in the conjunctiva. Although the healing rate was slower in the topical group, all corneas were almost healed within 96 h

Full Text available with Trip Pro

2016 BMC Ophthalmology

109. Does Order of Application of Emollient and Topical Corticosteroids Make a Difference in the Severity of Atopic Eczema in Children? (PubMed)

Does Order of Application of Emollient and Topical Corticosteroids Make a Difference in the Severity of Atopic Eczema in Children? Atopic eczema (AE) is a common chronic inflammatory skin disorder in children, with emollients and topical corticosteroids (TCSs) commonly prescribed as treatment. There is no published guidance on the correct order of application of emollient and TCS in children with AE.The objective of this study was to determine whether the order of application of emollient (...) and that parents can apply topical medications in whichever order they prefer.© 2016 Wiley Periodicals, Inc.

2016 Pediatric dermatology

110. Topical Corticosteroid Concerns in Dermatological Outpatients: A Cross-Sectional and Interventional Study. (PubMed)

Topical Corticosteroid Concerns in Dermatological Outpatients: A Cross-Sectional and Interventional Study. Topical corticosteroid concerns (TCC) are an important issue in patients with atopic dermatitis, leading to non-adherence with poor disease control and increased health care costs. However, neither the prevalence of TCC in a more comprehensible dermatological population nor the impact of patient information on topical corticosteroids given by clinicians is known. Therefore, we assessed (...) the prevalence, characteristics, and sources of TCC in a dermatological population and the impact of written and oral patient information on TCC.A total of 643 outpatients with various skin diseases answered a 12-item questionnaire while waiting for the doctor's visit. Patients with TCC quantified their concerns on a discrete visual analogue scale before and after patient information, which consisted of written and oral information about topical corticosteroids (TCS) given by dermatologists.The prevalence

2016 Dermatology

111. Effect of sodium hyluronate added to topical corticosteroids in chronic rhinosinusitis with nasal polyposis. (PubMed)

Effect of sodium hyluronate added to topical corticosteroids in chronic rhinosinusitis with nasal polyposis. Available medical treatments for chronic rhinosinusitis (CRS) with nasal polyposis (CRSwNP) comprise systemic and topical therapies. Although topical corticosteroids are effective in the treatment of CRS, they are not completely devoid of adverse effects. Thus, care has to be taken when long-term treatments are prescribed. There is recent evidence that sodium hyaluronate (SH), the major (...) component of many extracellular matrices, promotes tissue healing, including activation and moderation of the inflammatory responses, cell proliferation, migration, and angiogenesis.The aim of the study was to evaluate clinical outcomes and quality of life in two groups of patients with CRSwNP treated with topical corticosteroids alone or in combination with 9 mg of high-molecular-weight SH.The impact of treatments was determined by using nasal endoscopy and validated quality of life questionnaires

2016 American journal of rhinology & allergy

112. Topical application of a vitamin D3 analogue and corticosteroid to psoriasis plaques decreases skin infiltration of T<sub>H</sub>17 cells and their ex vivo expansion. (PubMed)

Topical application of a vitamin D3 analogue and corticosteroid to psoriasis plaques decreases skin infiltration of TH17 cells and their ex vivo expansion. Topical combination of a vitamin D3 analogue and corticosteroid is widely used for the treatment of psoriasis, a TH17-mediated disorder, but the underlying mechanism remains unclear.We investigated the effect of this topical applicant, focusing on skin-infiltrating TH17 cells.In 10 patients with plaque psoriasis, calcipotriol (Cal (...) improvement was found in the following order: CB > Cal > Bet > control or CB > Bet > Cal > control. Numbers of ex vivo expanded T cells were decreased by topical application of Bet and CB, and CB exhibited the most suppressive result. Numbers and frequencies of TH17 cells were significantly reduced by CB and Cal, suggesting that Cal has a capacity to preferentially suppress TH17 cells. When the stocked T cells from control samples were stimulated with anti-CD3 antibodies in the presence of Bet, Cal

2016 Journal of Allergy and Clinical Immunology

113. Topical versus oral antibiotics, with or without corticosteroids, in the treatment of tympanostomy tube otorrhea. (PubMed)

Topical versus oral antibiotics, with or without corticosteroids, in the treatment of tympanostomy tube otorrhea. Antibiotic treatment is the standard of care for tympanostomy tube otorrhea. This meta-analysis aims to evaluate the efficacy of topical antibiotics with or without corticosteroids versus oral antibiotics in the treatment of tube otorrhea in children.MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials and ProQuest.The above databases were searched using a search strategy (...) corticosteroids as an adjunct to topical antibiotics.Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

2016 International Journal of Pediatric Otorhinolaryngology

114. Impact of the Topical Ophthalmic Corticosteroid Loteprednol Etabonate on Intraocular Pressure (PubMed)

Impact of the Topical Ophthalmic Corticosteroid Loteprednol Etabonate on Intraocular Pressure Corticosteroids are a mainstay therapeutic option for the treatment of ocular inflammation. However, safety remains a concern for clinicians, particularly with long-term use. Though highly effective at suppressing inflammatory and allergic responses, topical ophthalmic corticosteroids carry an inherent risk of side effects, including elevated intraocular pressure (IOP), a risk factor (...) for the development of glaucoma. The corticosteroid loteprednol etabonate (LE) contains an ester rather than a ketone at the C-20 position, minimizing the potential for side effects, including IOP elevation. In early pivotal clinical trials of LE ophthalmic suspension for conjunctivitis (allergic, giant papillary), anterior uveitis, and post-operative inflammation, LE had minimal impact on IOP over short-term (<28 days) and long-term (≥28 days) use. Since then, new LE formulations-including a gel, an ointment

Full Text available with Trip Pro

2016 Advances in therapy

115. Topical Corticosteroid

Topical Corticosteroid Topical Corticosteroid Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Topical Corticosteroid Topical (...) Corticosteroid Aka: Topical Corticosteroid , Topical Steroid , Clobetasol Propionate , Betamethasone Dipropionate , Triamcinolone Acetonide , Fluocinolone Acetonide , Hydrocortisone Cream , Hydrocortisone Topical , Halobetasol Propionate , Ultravate , Temovate , Diprolene , Diflorasone diacetate , Psorcon , Amcinonide , Cyclocort , Diprosone , Mometasone furoate , Elocon , Florone , Fluocinonide , Lidex , Maxiflor , Desoximetasone , Topicort , Halcinonide , Halog , Hydrocortisone valerate , Westcort

2018 FP Notebook

116. Evaluation of the influence of pharmacists and GPs on patient perceptions of long-term topical corticosteroid use. (PubMed)

Evaluation of the influence of pharmacists and GPs on patient perceptions of long-term topical corticosteroid use. To assess pharmacist and general practitioner (GP) advice and behaviors, as related to and reported by patients and parents of patients using topical corticosteroids (TCS) on a long-term basis.Multicenter cross-sectional survey of patients (aged 18+) and parents of pediatric patients (aged <18) with a history of long-term (≥1 month) TCS use, assessing: TCS treatment adherence

2016 Journal of Dermatological Treatment

117. Safety of Topical Corticosteroids in Pregnancy. (PubMed)

Safety of Topical Corticosteroids in Pregnancy. Are topical corticosteroids safe for use in pregnancy?The available evidence found no associations of maternal use of topical corticosteroids of any potency with mode of delivery, birth defects, preterm delivery, fetal death, and low Apgar score. However, maternal use of potent to very potent topical corticosteroids, especially when the cumulative dosage of topical corticosteroids throughout the pregnancy is very large, is associated with low

2016 JAMA dermatology (Chicago, Ill.)

118. Assessment of "corticophobia" as an indicator of non-adherence to topical corticosteroids: A pilot study. (PubMed)

Assessment of "corticophobia" as an indicator of non-adherence to topical corticosteroids: A pilot study. Concerns regarding topical corticosteroid (TCS) use, broadly known as "corticophobia", are highly prevalent among dermatology patients and often result in non-adherence to TCS. This non-adherence contributes to poor disease control and increased health care costs. However, it is unknown if assessment of these concerns might help to identify patients at risk of TCS-non-adherence. Clinical (...) tools indicating non-adherence could be helpful to improve management of this patient group.To assess whether the available tools for measuring concerns regarding corticosteroids, the TOPICOP scale and the 0-10 Visual Analogue Scale (VAS), could help to detect non-adherence to TCS.In 75 patients with concerns regarding TCS use both the TOPICOP scale and VAS were anonymously assessed. A comparison was made between TCS-adherent and non-adherent patients regarding the intensity and characteristics

2016 Journal of Dermatological Treatment

119. Topical Corticosteroid Misuse: The Scenario in Patients Attending a Tertiary Care Hospital in New Delhi (PubMed)

Topical Corticosteroid Misuse: The Scenario in Patients Attending a Tertiary Care Hospital in New Delhi Irrational use of Topical Corticosteroid (TC) is quite common in India due to unrestricted availability and use of TC not only by general public but also by physicians and chemists due to quick relief of symptoms in different dermatological conditions.The present study was conducted to evaluate and analyse the prevalence of misuse of TC and the causes behind misuse of TC among patients

Full Text available with Trip Pro

2016 Journal of clinical and diagnostic research : JCDR

120. A prospective study of atopic dermatitis managed without topical corticosteroids for a 6-month period (PubMed)

A prospective study of atopic dermatitis managed without topical corticosteroids for a 6-month period Topical corticosteroids (TCS) are regarded as the mainstay treatment for atopic dermatitis (AD). As AD has a tendency to heal naturally, the long-term efficacy of TCS in AD management should be compared with the outcomes seen in patients with AD not using TCS. However, there are few long-term studies that consider patients with AD not using TCS. We designed a prospective multicenter cohort

Full Text available with Trip Pro

2016 Clinical, cosmetic and investigational dermatology

To help you find the content you need quickly, you can filter your results via the categories on the right-hand side >>>>