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Topical Corticosteroid

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101. Medical adherence to topical corticosteroid preparations prescribed for psoriasis: A systematic review. (PubMed)

Medical adherence to topical corticosteroid preparations prescribed for psoriasis: A systematic review. Topical corticosteroids and corticosteroid combinations are the principal treatments in psoriasis. The aim of this study was to investigate published literature dealing with medical adherence to topical corticosteroid or corticosteroid combinations in patients with psoriasis.Systematic electronic searches in English language literature were done until September 2015 without publication date (...) determinants of nonadherence were found. One designed intervention consisted of a disease management program, which improved adherence in the study period. Overall, the studies included were heterogeneous in design and had a high risk of bias.To improve health outcome in topical treatment of psoriasis, further studies should be conducted addressing determinants of nonadherence and test interventions to improve adherence. Validated measurements of medical nonadherence, prescription registers, or medication

2016 The Journal of dermatological treatment

102. Monitoring of topical corticosteroid phobia in a population of parents with children with atopic dermatitis using the TOPICOP<sup>®</sup> scale: prevalence, risk factors and the impact of therapeutic patient education. (PubMed)

Monitoring of topical corticosteroid phobia in a population of parents with children with atopic dermatitis using the TOPICOP® scale: prevalence, risk factors and the impact of therapeutic patient education. 27608366 2017 03 15 1468-3083 31 3 2017 Mar Journal of the European Academy of Dermatology and Venereology : JEADV J Eur Acad Dermatol Venereol Monitoring of topical corticosteroid phobia in a population of parents with children with atopic dermatitis using the TOPICOP ® scale

2016 Journal of the European Academy of Dermatology and Venereology

103. The effects of oral and topical corticosteroid in rabbit corneas. (PubMed)

The effects of oral and topical corticosteroid in rabbit corneas. To determine the most effective route of administration of corticosteroids in the treatment of ocular surface disease, by characterizing the difference between oral prednisolone and topical dexamethasone administration using an animal model.Pharmacokinetic analyses determined the corticosteroid concentrations in the normal ocular tissues of rabbits after oral or topical administration of corticosteroids using LC-MS/MS. In wound (...) observed between orally and topically administered groups. Pharmacokinetic analyses showed that the distribution of dexamethasone after topical administration was superior to that after oral administration in the cornea. In contrast, both concentrations of corticosteroid applied topically and orally were similar with regards to AUCs (area under the concentration-time curve) in the conjunctiva. Although the healing rate was slower in the topical group, all corneas were almost healed within 96 h

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2016 BMC Ophthalmology

104. Does Order of Application of Emollient and Topical Corticosteroids Make a Difference in the Severity of Atopic Eczema in Children? (PubMed)

Does Order of Application of Emollient and Topical Corticosteroids Make a Difference in the Severity of Atopic Eczema in Children? Atopic eczema (AE) is a common chronic inflammatory skin disorder in children, with emollients and topical corticosteroids (TCSs) commonly prescribed as treatment. There is no published guidance on the correct order of application of emollient and TCS in children with AE.The objective of this study was to determine whether the order of application of emollient (...) and that parents can apply topical medications in whichever order they prefer.© 2016 Wiley Periodicals, Inc.

2016 Pediatric dermatology

105. Effects of topical corticosteroid administration on intraocular pressure in normal and glaucomatous cats. (PubMed)

Effects of topical corticosteroid administration on intraocular pressure in normal and glaucomatous cats. The objective of this study was to determine the effect of topical corticosteroid (CCS) therapy on intraocular pressure (IOP) in normal cats and cats with primary feline congenital glaucoma (FCG).Five normal and 11 FCG cats were studied in two cohorts.IOP was measured by a single, masked observer, once daily, 3-5 days/week throughout the course of CCS treatment and for up to 11 days after (...) treatment discontinuation. One eye per cat was randomly assigned for treatment twice daily with CCS; balanced salt solution (BSS) applied to the contralateral eye served as a control. Differences between eyes and between weeks of the study period were calculated for each cat. A positive response to CCS was defined as a consistent >15% or >25% higher IOP in the treated relative to control eye in normal and FCG cats, respectively.A total of 8 of 11 FCG cats responded to topical CCS after 1-5 weeks

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2016 Veterinary ophthalmology

106. Topical Corticosteroid Concerns in Dermatological Outpatients: A Cross-Sectional and Interventional Study. (PubMed)

Topical Corticosteroid Concerns in Dermatological Outpatients: A Cross-Sectional and Interventional Study. Topical corticosteroid concerns (TCC) are an important issue in patients with atopic dermatitis, leading to non-adherence with poor disease control and increased health care costs. However, neither the prevalence of TCC in a more comprehensible dermatological population nor the impact of patient information on topical corticosteroids given by clinicians is known. Therefore, we assessed (...) the prevalence, characteristics, and sources of TCC in a dermatological population and the impact of written and oral patient information on TCC.A total of 643 outpatients with various skin diseases answered a 12-item questionnaire while waiting for the doctor's visit. Patients with TCC quantified their concerns on a discrete visual analogue scale before and after patient information, which consisted of written and oral information about topical corticosteroids (TCS) given by dermatologists.The prevalence

2016 Dermatology

107. Effect of sodium hyluronate added to topical corticosteroids in chronic rhinosinusitis with nasal polyposis. (PubMed)

Effect of sodium hyluronate added to topical corticosteroids in chronic rhinosinusitis with nasal polyposis. Available medical treatments for chronic rhinosinusitis (CRS) with nasal polyposis (CRSwNP) comprise systemic and topical therapies. Although topical corticosteroids are effective in the treatment of CRS, they are not completely devoid of adverse effects. Thus, care has to be taken when long-term treatments are prescribed. There is recent evidence that sodium hyaluronate (SH), the major (...) component of many extracellular matrices, promotes tissue healing, including activation and moderation of the inflammatory responses, cell proliferation, migration, and angiogenesis.The aim of the study was to evaluate clinical outcomes and quality of life in two groups of patients with CRSwNP treated with topical corticosteroids alone or in combination with 9 mg of high-molecular-weight SH.The impact of treatments was determined by using nasal endoscopy and validated quality of life questionnaires

2016 American journal of rhinology & allergy

108. Topical application of a vitamin D3 analogue and corticosteroid to psoriasis plaques decreases skin infiltration of T<sub>H</sub>17 cells and their ex vivo expansion. (PubMed)

Topical application of a vitamin D3 analogue and corticosteroid to psoriasis plaques decreases skin infiltration of TH17 cells and their ex vivo expansion. Topical combination of a vitamin D3 analogue and corticosteroid is widely used for the treatment of psoriasis, a TH17-mediated disorder, but the underlying mechanism remains unclear.We investigated the effect of this topical applicant, focusing on skin-infiltrating TH17 cells.In 10 patients with plaque psoriasis, calcipotriol (Cal (...) improvement was found in the following order: CB > Cal > Bet > control or CB > Bet > Cal > control. Numbers of ex vivo expanded T cells were decreased by topical application of Bet and CB, and CB exhibited the most suppressive result. Numbers and frequencies of TH17 cells were significantly reduced by CB and Cal, suggesting that Cal has a capacity to preferentially suppress TH17 cells. When the stocked T cells from control samples were stimulated with anti-CD3 antibodies in the presence of Bet, Cal

2016 Journal of Allergy and Clinical Immunology

109. Topical versus oral antibiotics, with or without corticosteroids, in the treatment of tympanostomy tube otorrhea. (PubMed)

Topical versus oral antibiotics, with or without corticosteroids, in the treatment of tympanostomy tube otorrhea. Antibiotic treatment is the standard of care for tympanostomy tube otorrhea. This meta-analysis aims to evaluate the efficacy of topical antibiotics with or without corticosteroids versus oral antibiotics in the treatment of tube otorrhea in children.MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials and ProQuest.The above databases were searched using a search strategy (...) corticosteroids as an adjunct to topical antibiotics.Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

2016 International Journal of Pediatric Otorhinolaryngology

110. Impact of the Topical Ophthalmic Corticosteroid Loteprednol Etabonate on Intraocular Pressure (PubMed)

Impact of the Topical Ophthalmic Corticosteroid Loteprednol Etabonate on Intraocular Pressure Corticosteroids are a mainstay therapeutic option for the treatment of ocular inflammation. However, safety remains a concern for clinicians, particularly with long-term use. Though highly effective at suppressing inflammatory and allergic responses, topical ophthalmic corticosteroids carry an inherent risk of side effects, including elevated intraocular pressure (IOP), a risk factor (...) for the development of glaucoma. The corticosteroid loteprednol etabonate (LE) contains an ester rather than a ketone at the C-20 position, minimizing the potential for side effects, including IOP elevation. In early pivotal clinical trials of LE ophthalmic suspension for conjunctivitis (allergic, giant papillary), anterior uveitis, and post-operative inflammation, LE had minimal impact on IOP over short-term (<28 days) and long-term (≥28 days) use. Since then, new LE formulations-including a gel, an ointment

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2016 Advances in therapy

111. Topical Corticosteroid

Topical Corticosteroid Topical Corticosteroid Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Topical Corticosteroid Topical (...) Corticosteroid Aka: Topical Corticosteroid , Topical Steroid , Clobetasol Propionate , Betamethasone Dipropionate , Triamcinolone Acetonide , Fluocinolone Acetonide , Hydrocortisone Cream , Hydrocortisone Topical , Halobetasol Propionate , Ultravate , Temovate , Diprolene , Diflorasone diacetate , Psorcon , Amcinonide , Cyclocort , Diprosone , Mometasone furoate , Elocon , Florone , Fluocinonide , Lidex , Maxiflor , Desoximetasone , Topicort , Halcinonide , Halog , Hydrocortisone valerate , Westcort

2018 FP Notebook

112. Topical corticosteroid has no influence on inflammation or efficacy after ingenol mebutate treatment of grade I to III actinic keratoses (AK): A randomized clinical trial. (PubMed)

Topical corticosteroid has no influence on inflammation or efficacy after ingenol mebutate treatment of grade I to III actinic keratoses (AK): A randomized clinical trial. Ingenol mebutate (IngMeb) is approved for treatment of actinic keratoses (AK) and may cause unpredictable local skin responses (LSR).We sought to investigate whether IngMeb-induced LSR, pain, and pruritus could be alleviated with a topical glucocorticoid and, further, to assess efficacy, cosmetic outcome, and patient (...) satisfaction in patients with severe photodamage.In this blinded, randomized controlled clinical trial, patients with multiple AK and field cancerization of the face or scalp were treated in 2 areas with IngMeb (0.015%) daily for 3 days. After finalized IngMeb treatment, 1 area was randomized to receive topical clobetasol propionate (0.05%) twice daily for 4 days. Assessments included LSR (0-24; days 1, 4, 8, 15, 57), pain (0-10) and pruritus (0-3; days 1-15), AK clearance (days 15, 57), and cosmetic

2016 Journal of the American Academy of Dermatology

113. Evaluation of the influence of pharmacists and GPs on patient perceptions of long-term topical corticosteroid use. (PubMed)

Evaluation of the influence of pharmacists and GPs on patient perceptions of long-term topical corticosteroid use. To assess pharmacist and general practitioner (GP) advice and behaviors, as related to and reported by patients and parents of patients using topical corticosteroids (TCS) on a long-term basis.Multicenter cross-sectional survey of patients (aged 18+) and parents of pediatric patients (aged <18) with a history of long-term (≥1 month) TCS use, assessing: TCS treatment adherence

2016 Journal of Dermatological Treatment

114. Safety of Topical Corticosteroids in Pregnancy. (PubMed)

Safety of Topical Corticosteroids in Pregnancy. Are topical corticosteroids safe for use in pregnancy?The available evidence found no associations of maternal use of topical corticosteroids of any potency with mode of delivery, birth defects, preterm delivery, fetal death, and low Apgar score. However, maternal use of potent to very potent topical corticosteroids, especially when the cumulative dosage of topical corticosteroids throughout the pregnancy is very large, is associated with low

2016 JAMA dermatology (Chicago, Ill.)

115. Assessment of "corticophobia" as an indicator of non-adherence to topical corticosteroids: A pilot study. (PubMed)

Assessment of "corticophobia" as an indicator of non-adherence to topical corticosteroids: A pilot study. Concerns regarding topical corticosteroid (TCS) use, broadly known as "corticophobia", are highly prevalent among dermatology patients and often result in non-adherence to TCS. This non-adherence contributes to poor disease control and increased health care costs. However, it is unknown if assessment of these concerns might help to identify patients at risk of TCS-non-adherence. Clinical (...) tools indicating non-adherence could be helpful to improve management of this patient group.To assess whether the available tools for measuring concerns regarding corticosteroids, the TOPICOP scale and the 0-10 Visual Analogue Scale (VAS), could help to detect non-adherence to TCS.In 75 patients with concerns regarding TCS use both the TOPICOP scale and VAS were anonymously assessed. A comparison was made between TCS-adherent and non-adherent patients regarding the intensity and characteristics

2016 Journal of Dermatological Treatment

116. Topical Corticosteroid Misuse: The Scenario in Patients Attending a Tertiary Care Hospital in New Delhi (PubMed)

Topical Corticosteroid Misuse: The Scenario in Patients Attending a Tertiary Care Hospital in New Delhi Irrational use of Topical Corticosteroid (TC) is quite common in India due to unrestricted availability and use of TC not only by general public but also by physicians and chemists due to quick relief of symptoms in different dermatological conditions.The present study was conducted to evaluate and analyse the prevalence of misuse of TC and the causes behind misuse of TC among patients

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2016 Journal of clinical and diagnostic research : JCDR

117. A prospective study of atopic dermatitis managed without topical corticosteroids for a 6-month period (PubMed)

A prospective study of atopic dermatitis managed without topical corticosteroids for a 6-month period Topical corticosteroids (TCS) are regarded as the mainstay treatment for atopic dermatitis (AD). As AD has a tendency to heal naturally, the long-term efficacy of TCS in AD management should be compared with the outcomes seen in patients with AD not using TCS. However, there are few long-term studies that consider patients with AD not using TCS. We designed a prospective multicenter cohort

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2016 Clinical, cosmetic and investigational dermatology

118. Topical corticosteroid concerns from the clinicians' perspective. (PubMed)

Topical corticosteroid concerns from the clinicians' perspective. Topical corticosteroids concerns (TCC) are common in dermatology patients, possibly leading to non-adherence to topical corticosteroids (TCS) and poor disease control. Clinicians play a key role in that context, as they can reduce or reinforce these concerns. It is unknown, if clinicians have accurate knowledge of TCC to appropriately address this issue and whether they have concerns themselves to use TCS. This questionnaire

2016 Journal of Dermatological Treatment

119. Clinical scores of sleep loss/itch and antihistamine/topical corticosteroid usage for childhood eczema. (PubMed)

Clinical scores of sleep loss/itch and antihistamine/topical corticosteroid usage for childhood eczema. 27061407 2017 09 11 2017 09 11 1365-2133 175 5 2016 Nov The British journal of dermatology Br. J. Dermatol. Clinical scores of sleep loss and itch, and antihistamine and topical corticosteroid usage for childhood eczema. 1076-1078 10.1111/bjd.14660 Hon K L KL Department of Pediatrics, The Chinese University of Hong Kong, 6/F, Clinical Science Building, Prince of Wales Hospital, Shatin, Hong

2016 British Journal of Dermatology

120. Topical corticosteroids effective for nasal polyps

Topical corticosteroids effective for nasal polyps Topical corticosteroids effective for nasal polyps | Cochrane Primary Care Trusted evidence. Informed decisions. Better health. Enter terms Topical corticosteroids effective for nasal polyps Cochrane Trusted evidence. Informed decisions. Better health. Copyright © 2019 The Cochrane Collaboration | | We use cookies to improve your experience on our site.

2013 Cochrane PEARLS

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