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Topical Corticosteroid

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81. Misuse of topical corticosteroids on facial skin. A study of 200 patients. (PubMed)

Misuse of topical corticosteroids on facial skin. A study of 200 patients. Topical corticosteroids have become available as over the counter drugs and are widely misused for various conditions.The aim of this study is to assess the clinical and epidemiological aspects of the unjustified use of topical corticosteroids for facial skin.A total of 200 patients with facial dermatoses and topical corticosteroid misapplication daily over face for not less than 30 days were included in the study (...) . This was a prospective study conducted in a tertiary care dermatology outpatient centre of the Jammu region. A detailed clinical history regarding topical corticosteroid use was taken and adverse effects analysed.A total of 166 patients were women and 34 were men. The predominant age was 31-40 years. A total of 170 patients (85%) were in the age group of 21-50 years. Duration of application was over 1 month up to 3 years, daily. Betamethasone or clobetasol ointments were used in 75 patients (37.5%) and momatasone

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2017 Journal of dermatological case reports

82. Xerostomia and Salivary Gland Hypofunction in Patients with Oral Lichen Planus Before and After Treatment with Topical Corticosteroids (PubMed)

Xerostomia and Salivary Gland Hypofunction in Patients with Oral Lichen Planus Before and After Treatment with Topical Corticosteroids Oral lichen planus and mouth dryness are common pathoses, yet not entirely understood. These two conditions may be associated, with a few studies investigating the relationship between mouth dryness and oral lichen planus providing conflicting results. None of the studies have explored the specific impact of disease treatment on mouth dryness.The purpose (...) of this observational before and after comparison study was to examine the effect of treatment of oral lichen planus with topical corticosteroids on mouth dryness.Nineteen subjects with oral lichen planus were evaluated for the severity of xerostomia using a xerostomia inventory and a visual analogue scale. Stimulated and unstimulated whole salivary flow rates, unstimulated salivary pH and buffering capacity were also measured. All subjects were evaluated before and after treatment with topical corticosteroids.All

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2017 The open dentistry journal

83. Topical corticosteroids knowledge, attitudes, and practices of primary care physicians (PubMed)

Topical corticosteroids knowledge, attitudes, and practices of primary care physicians To assess knowledge, attitudes, and practices of primary care physicians (PCPs) toward topical corticosteroids (TCs). Methods: A cross-sectional, 53-item questionnaire based study on TCs was conducted among PCPs in Riyadh, Kingdom of Saudi Arabia between January and March 2015. A maximum score of 30 was calculated for the knowledge portion. Results: Out of 420 PCPs, 336 responded (80%). Most participants

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2017 Saudi medical journal

84. Knowledge, Attitude and Advice-Giving Behaviour of Community Pharmacists Regarding Topical Corticosteroids (PubMed)

Knowledge, Attitude and Advice-Giving Behaviour of Community Pharmacists Regarding Topical Corticosteroids This study examines the relationship between community pharmacists' knowledge, attitudes to information provision and self-reported counselling behaviours in relation to topical corticosteroids and adjunct therapy in atopic eczema. A mixed-methods approach was used whereby data from interviews with community pharmacists were used to design a structured questionnaire that a larger sample (...) of community pharmacists completed anonymously. The questionnaire was completed and returned by 105 pharmacists (36% response rate). Pharmacists showed gaps in their knowledge on the use of topical corticosteroids in atopic eczema but had good understanding on the use of emollients. There was a significant correlation between pharmacists' attitudes to information provision and their self-reported counselling behaviour for most themes except in relation to corticosteroid safety where less advice was given

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2017 Pharmacy: Journal of Pharmacy Education and Practice

85. Misuse of Topical Corticosteroids for Cosmetic Purpose in Antananarivo, Madagascar (PubMed)

Misuse of Topical Corticosteroids for Cosmetic Purpose in Antananarivo, Madagascar This cross-sectional study was conducted in Antananarivo, Madagascar, from June to September 2012. We aim to evaluate the misuse of TC on the face for cosmetic purpose and the adverse effects due to its application. A questionnaire-based analysis was done among females who use topical corticosteroids on the face for cosmetic purpose. Of the 770 women questioned, 384 (49,8%) used topical corticosteroids

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2017 BioMed research international

86. Bioequivalence Methodologies for Topical Drug Products: In Vitro and Ex Vivo Studies with a Corticosteroid and an Anti-Fungal Drug (PubMed)

Bioequivalence Methodologies for Topical Drug Products: In Vitro and Ex Vivo Studies with a Corticosteroid and an Anti-Fungal Drug To examine whether in vitro and ex vivo measurements of topical drug product performance correlate with in vivo outcomes, such that more efficient experimental approaches can be reliably and reproducibly used to establish (in)equivalence between formulations for skin application.In vitro drug release through artificial membranes, and drug penetration into porcine (...) vivo did not parallel that in vivo, presumably due to the absence of a functioning microcirculation. In vitro release of BMV from the different formulations did not overlap with either ex vivo or in vivo tape-stripping data whereas, for EN, a good correlation was observed. No measurable permeation of either BMV or EN was detected in a 6-h in vitro skin penetration experiment.In vitro and ex vivo methods for topical bioequivalence determination can show correlation with in vivo outcomes. However

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2017 Pharmaceutical research

87. Topical corticosteroid withdrawal in a pediatric patient (PubMed)

Topical corticosteroid withdrawal in a pediatric patient 28932784 2019 02 26 2352-5126 3 5 2017 Sep JAAD case reports JAAD Case Rep Topical corticosteroid withdrawal in a pediatric patient. 420-421 10.1016/j.jdcr.2017.06.006 Dhossche Julie J Department of Dermatology, Oregon Health and Science University, Portland, Oregon. Simpson Eric E Department of Dermatology, Oregon Health and Science University, Portland, Oregon. Hajar Tamar T Department of Dermatology, Oregon Health and Science (...) University, Portland, Oregon. eng Case Reports 2017 09 08 United States JAAD Case Rep 101665210 2352-5126 ED, emergency department TCS, topical corticosteroids atopic dermatitis pediatrics steroid withdrawal syndrome topical corticosteroids 2017 9 22 6 0 2017 9 22 6 0 2017 9 22 6 1 epublish 28932784 10.1016/j.jdcr.2017.06.006 S2352-5126(17)30118-2 PMC5594228 Br Med J. 1968 Mar 2;1(5591):579-80 4231359 J Am Acad Dermatol. 2015 Mar;72(3):541-549.e2 25592622 Br Med J. 1969 Mar 15;1(5645):671-3 4237682 Arch

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2017 JAAD Case Reports

88. Efficacy and Safety of Topical Corticosteroids for Management of Oral Chronic Graft versus Host Disease (PubMed)

Efficacy and Safety of Topical Corticosteroids for Management of Oral Chronic Graft versus Host Disease Oral chronic graft versus host disease (cGVHD) is a major complication in transplantation community, a problem that can be addressed with topical intervention. Topical corticosteroids are the first line of treatment although the choice remains challenging as none of the available treatments is supported by strong clinical evidence.This systematic review aims to determine the clinical efficacy (...) and safety of topical corticosteroids for the management of the mucosal alterations of oral cGVHD.Electronic search of different databases was conducted: PubMed, Cochrane library, Grey literature, WHO, and clinical trials.gov for clinical trial registration as well as hand search in the references of relevant articles up to November 2016.Extracted pieces of information were intervention, population, sample sizes, and outcomes.Six studies were included: 2 randomized clinical trials (RCTs), 3 cohort

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2017 International journal of dentistry

89. Change of Oral to Topical Corticosteroid Therapy Exacerbated Glucose Tolerance in a Patient with Plaque Psoriasis (PubMed)

Change of Oral to Topical Corticosteroid Therapy Exacerbated Glucose Tolerance in a Patient with Plaque Psoriasis BACKGROUND Psoriasis is known as the most frequent disease treated by long-term topical steroids. It is also known that patients with thick, chronic plaques require the highest potency topical steroids. However, the treatment is limited to up to four weeks due to risk of systemic absorption. CASE REPORT An 80-year-old man was diagnosed with type 2 diabetes 16 years before (...) , and was being administered insulin combined with alpha glucosidase inhibitor. He was diagnosed with plaque psoriasis and his oral steroid treatment was switched to topical steroid treatment due to lack of improvement and poorly controlled blood glucose level. The hypoglycemic events improved after the psoriatic lesions improved. CONCLUSIONS Control of blood glucose level is difficult at the very beginning of topical steroid treatment for psoriasis especially if a patient is receiving insulin treatment

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2017 The American journal of case reports

90. Intranasal Corticosteroids for the Management of Chronic Rhinosinusitis or Nasal Polyposis in Cystic Fibrosis: A Review of Clinical Effectiveness

trial reported that a topical steroid (betamethasone) was effective in reducing the size of nasal polyps for people with cystic fibrosis, without significant improvement in nasal symptoms. There was insufficient evidence to support or refute the use of intranasal corticosteroids for treatment of chronic rhinosinusitis or polyposis for those with cystic fibrosis. Files Rapid Response Summary with Critical Appraisal Published : March 18, 2019 Follow us: © 2019 Canadian Agency for Drugs (...) Intranasal Corticosteroids for the Management of Chronic Rhinosinusitis or Nasal Polyposis in Cystic Fibrosis: A Review of Clinical Effectiveness Intranasal Corticosteroids for the Management of Chronic Rhinosinusitis or Nasal Polyposis in Cystic Fibrosis: A Review of Clinical Effectiveness | CADTH.ca Find the information you need Intranasal Corticosteroids for the Management of Chronic Rhinosinusitis or Nasal Polyposis in Cystic Fibrosis: A Review of Clinical Effectiveness Intranasal

2019 Canadian Agency for Drugs and Technologies in Health - Rapid Review

91. Antenatal Corticosteroid Therapy for Improving Neonatal Outcomes

Institutes of Health, the American College of Obstetricians and Gynecologists, the Society for Maternal Fetal Medicine, the Royal College of Obstetricians and Gynaecologists, and the Canadian Pediatric Society were reviewed for additional references. Randomized controlled trials conducted in pregnant women evaluating antenatal corticosteroid therapy and previous systematic reviews on the topic were eligible. Evidence from systematic reviews of non-experimental (cohort) studies was also eligible (...) Antenatal Corticosteroid Therapy for Improving Neonatal Outcomes No. 364-Antenatal Corticosteroid Therapy for Improving Neonatal Outcomes - Journal of Obstetrics and Gynaecology Canada Email/Username: Password: Remember me Search Terms Search within Search Volume 40, Issue 9, Pages 1219–1239 No. 364-Antenatal Corticosteroid Therapy for Improving Neonatal Outcomes x Amanda Skoll , MD * Vancouver, BC x Amélie Boutin , PhD * Québec City, QC x Emmanuel Bujold , MD, MSc Québec City, QC x Jason

2018 Society of Obstetricians and Gynaecologists of Canada

92. Corticosteroids

. If you wanted the latest trusted evidence on corticosteroids or other clinical topics then use Trip today. This page lists the very latest high quality evidence on corticosteroids and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months. What is Trip? Trip is a clinical search engine designed to allow users to quickly and easily find and use high-quality research evidence to support their practice (...) Corticosteroids Top results for corticosteroids - Trip Database or use your Google+ account Find evidence fast ALL of these words: Title only Anywhere in the document ANY of these words: Title only Anywhere in the document This EXACT phrase: Title only Anywhere in the document EXCLUDING words: Title only Anywhere in the document Timeframe: to: Combine searches by placing the search numbers in the top search box and pressing the search button. An example search might look like (#1 or #2) and (#3

2018 Trip Latest and Greatest

93. Inhaled versus systemic corticosteroids for the treatment of bronchopulmonary dysplasia in ventilated very low birth weight preterm infants. (PubMed)

of antenatal steroids and postnatal surfactant therapy to decrease the incidence and severity of respiratory distress syndrome. Due to their anti-inflammatory properties, corticosteroids have been widely used to treat or prevent BPD. However, the use of systemic steroids has been associated with serious short- and long-term adverse effects. Administration of corticosteroids topically through the respiratory tract may result in beneficial effects on the pulmonary system with fewer undesirable systemic side (...) Inhaled versus systemic corticosteroids for the treatment of bronchopulmonary dysplasia in ventilated very low birth weight preterm infants. This is an update of a review published in 2012. A related review "Inhaled versus systemic corticosteroids for preventing bronchopulmonary dysplasia in ventilated very low birth weight preterm neonates" has been updated as well. Bronchopulmonary dysplasia (BPD) is a serious and common problem among very low birth weight infants, despite the use

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2017 Cochrane

94. Non-steroidal anti-inflammatory drugs versus corticosteroids for controlling inflammation after uncomplicated cataract surgery. (PubMed)

, but these two drug classes work by different mechanisms. Corticosteroids are effective, but NSAIDs may provide an additional benefit to reduce inflammation when given in combination with corticosteroids. A comparison of NSAIDs to corticosteroids alone or combination therapy with these two anti-inflammatory agents will help to determine the role of NSAIDs in controlling inflammation after routine cataract surgery.To evaluate the comparative effectiveness of topical NSAIDs (alone or in combination (...) with topical corticosteroids) versus topical corticosteroids alone in controlling intraocular inflammation after uncomplicated phacoemulsification. To assess postoperative best-corrected visual acuity (BCVA), patient-reported discomfort, symptoms, or complications (such as elevation of IOP), and cost-effectiveness with the use of postoperative NSAIDs or corticosteroids.To identify studies relevant to this review, we searched the Cochrane Central Register of Controlled Trials (CENTRAL), which contains

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2017 Cochrane

95. Proliferative and necrotizing otitis externa in a kitten: successful treatment with intralesional and topical corticosteroid therapy (PubMed)

Proliferative and necrotizing otitis externa in a kitten: successful treatment with intralesional and topical corticosteroid therapy Proliferative and necrotising otitis externa (PNOE) is a very rare disease affecting the ear canals and concave pinnae of kittens. This report describes a 5-month-old cat with PNOE. Histopathological examination confirmed the diagnosis. Treatment was initiated with local injection of methylprednisolone acetate into the lesions. The cat was subsequently treated (...) with clobetasol propionate cream, a potent topical glucocorticoid ointment. The cat showed marked improvement. While topical treatment with tacrolimus, an immunosuppressive agent, is reported to be an effective therapy, to the best of our knowledge, this is the first report to treat PNOE with local corticosteroid therapy.

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2016 The Journal of Veterinary Medical Science

96. Topical Corticosteroid App

Topical Corticosteroid App Topical Corticosteroid App - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Topical Corticosteroid App The safety and scientific validity of this study is the responsibility (...) the effectiveness of a mobile application to assist in the prescription of topical corticosteroids (TCS), focusing on best fit choices of potency, vehicle and volume. The mobile application will be developed from the results obtained in a systematic literature review and quality assessment of clinical practice guidelines for topical corticosteroid use. The quality of the guidelines will be assessed using the AGREE II tool. After the app user enters in information concerning patients' rash location and desired

2016 Clinical Trials

97. Differences in therapeutic effects of topically applied corticosteroid and tacrolimus on atopic dermatitis-like symptoms in NC/Nga mice. (PubMed)

Differences in therapeutic effects of topically applied corticosteroid and tacrolimus on atopic dermatitis-like symptoms in NC/Nga mice. Topical corticosteroid and calcineurin inhibitor have similar therapeutic benefits in atopic dermatitis (AD), but the differences in therapeutic mechanisms of action of these agents against AD symptoms are not fully understood.This study was performed to examine the different effects of topical betamethasone valerate (BMV), clobetasol propionate (CBP (...) the strongest effect. CBP significantly reduced epidermal thickness compared with Vas and NT. There were no significant differences in the numbers of interleukin-31-immunoreactive cells and mast cells, or in expression of epidermal thymic stromal lymphopoietin among all five groups.The therapeutic potency of TAC against AD-like symptoms, including pruritus, is equal to that of the corticosteroid CBP. Epidermal innervation of sensory nerves itself might not be related to the therapeutic effects of topical

2016 Journal of dermatological science

98. Topical corticosteroids application in the evening is more effective than in the morning in psoriasis: results of a prospective comparative study. (PubMed)

Topical corticosteroids application in the evening is more effective than in the morning in psoriasis: results of a prospective comparative study. 27790782 2017 04 27 1468-3083 31 5 2017 May Journal of the European Academy of Dermatology and Venereology : JEADV J Eur Acad Dermatol Venereol Topical corticosteroids application in the evening is more effective than in the morning in psoriasis: results of a prospective comparative study. e263-e264 10.1111/jdv.14027 Nguyen S S Department

2016 Journal of the European Academy of Dermatology and Venereology

99. Carers' views of topical-corticosteroid use in childhood eczema: a qualitative study of online discussion forums. (PubMed)

Carers' views of topical-corticosteroid use in childhood eczema: a qualitative study of online discussion forums. Childhood eczema is very common and can have substantial impact on quality of life. One of the main treatments is topical corticosteroids, but these are often underused by parents and carers for reasons that include concerns about safety.To explore understandings and concerns about topical corticosteroids among parents and carers of children with eczema who had posted messages (...) in online forums.A qualitative study of messages and their resultant discussions about topical corticosteroids for childhood eczema posted by parents and carers on two U.K.-based discussion forums.Ninety-five forum users involved in 27 discussions relating to topical corticosteroid use in childhood eczema were identified dating from 2003 to 2015. Analysis of discussions highlighted three themes: (i) diverse beliefs about the use of topical corticosteroids; (ii) uncertainty and confusion about using

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2016 British Journal of Dermatology

100. Descemet's Membrane Endothelial Keratoplasty: Risk of Immunologic Rejection Episodes after Discontinuing Topical Corticosteroids. (PubMed)

Descemet's Membrane Endothelial Keratoplasty: Risk of Immunologic Rejection Episodes after Discontinuing Topical Corticosteroids. To assess the risk of immunologic rejection episodes if topical corticosteroids are discontinued 1 year after Descemet's membrane endothelial keratoplasty (DMEK) compared with continued once-per-day use.Prospective, longitudinal, parallel-group study.A total of 400 eyes of 259 DMEK recipients, aged 23 to 90 years.Patients were enrolled 1 year after DMEK and allowed (...) to choose whether to stop or continue once-daily topical corticosteroids to maximize compliance. Fellow eyes were eligible for enrollment because the donor grafts were independent. Participants were examined at 1, 3, 6, and 12 months during the second year after DMEK. Results were assessed using Kaplan-Meier survival analysis.Incidence of immunologic rejection episodes.Steroids were discontinued in 277 eyes (no steroid group) and continued once per day in 123 eyes (steroid group). The subject

2016 Ophthalmology

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