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Topical Corticosteroid

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61. Association of Topical Corticosteroid Use and Bone Mineral Density in Patients with Atopic Dermatitis

Association of Topical Corticosteroid Use and Bone Mineral Density in Patients with Atopic Dermatitis "Association of Topical Corticosteroid Use and Bone Mineral Density in " by Carsten Paulson < > > > > > Title Author Date of Graduation Summer 8-8-2015 Degree Type Capstone Project Degree Name Master of Science in Physician Assistant Studies First Advisor Annjanette Sommers, PA-C, MS Rights . Abstract Background Atopic dermatitis (AD) is a common pruritic inflammatory skin disease. First-line (...) therapy for AD involves the use of topical corticosteroids. With long-term use, these agents exert systemic effects and have been associated with adverse effects on bone health. This review assesses the current evidence for an association between topical corticosteroid use and bone mineral density in patients with atopic dermatitis. Methods An exhaustive search of available literature was conducted in using the MEDLINE-Ovid, Web of Science, CINAHL, and Evidence-Based Medicine Reviews Multifile

2015 Pacific University EBM Capstone Project

62. Low-dose oral theophylline combined with inhaled corticosteroids for people with chronic obstructive pulmonary disease and high risk of exacerbations: a RCT

Low-dose oral theophylline combined with inhaled corticosteroids for people with chronic obstructive pulmonary disease and high risk of exacerbations: a RCT Low-dose oral theophylline combined with inhaled corticosteroids for people with chronic obstructive pulmonary disease and high risk of exacerbations: a RCT Journals Library An error occurred retrieving content to display, please try again. >> >> >> Page Not Found Page not found (404) Sorry - the page you requested could not be found (...) . Please choose a page from the navigation or try a website search above to find the information you need. >> >> >> >> Issue {{metadata .Issue }} Toolkit 1)"> 0)"> 1)"> {{metadata.Title}} {{metadata.Headline}} Adding low-dose oral theophylline to inhaled corticosteroids did not reduce exacerbations over 1 year. {{author}} {{($index , , , , , , , , , , , , , , , , , , , & . Graham Devereux 1, * , Seonaidh Cotton 2 , Shona Fielding 3 , Nicola McMeekin 4 , Peter J Barnes 5 , Andy Briggs 4 , Graham Burns 6

2019 NIHR HTA programme

63. Corticosteroid therapy for sepsis

Corticosteroid therapy for sepsis Corticosteroid therapy for sepsis: a clinical practice guideline | The BMJ Intended for healthcare professionals Username * Password * Edition: Search form Search Search Corticosteroid therapy... Corticosteroid therapy for sepsis: a clinical practice guideline CC BY NC Open access (Published 10 August 2018) Cite this as: BMJ 2018;362:k3284 Population Recommendation applies to: Recommendation does not apply to: Adults and children Patients with pre-existing (...) adrenal insufficiency Non-infectious causes of shock Neonates Pregnant women Any infectious source Patients with and without shock Intra abdominal infections Pneumonia Anaphylactic Cardiogenic Hypovolaemic People with sepsis SOFA score of at least 2 Comparison or Corticosteroid therapy No corticosteroid therapy Usual care only Intravenous corticosteroids plus usual care Corticosteroids No corticosteroids Usual care Usual care + CCS More details We suggest corticosteroid therapy rather than

2018 BMJ Rapid Recommendations

64. Systematic review and meta-analysis of randomized clinical trials (RCTs) comparing topical corticosteroids with moisturizers for children (< 2 years old) with atopic dermatitis

Systematic review and meta-analysis of randomized clinical trials (RCTs) comparing topical corticosteroids with moisturizers for children (< 2 years old) with atopic dermatitis Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email

2017 PROSPERO

65. Intranasal Corticosteroids for the Management of Chronic Rhinosinusitis or Nasal Polyposis in Cystic Fibrosis: A Review of Clinical Effectiveness

trial reported that a topical steroid (betamethasone) was effective in reducing the size of nasal polyps for people with cystic fibrosis, without significant improvement in nasal symptoms. There was insufficient evidence to support or refute the use of intranasal corticosteroids for treatment of chronic rhinosinusitis or polyposis for those with cystic fibrosis. Files Rapid Response Summary with Critical Appraisal Published : March 18, 2019 Follow us: © 2019 Canadian Agency for Drugs (...) Intranasal Corticosteroids for the Management of Chronic Rhinosinusitis or Nasal Polyposis in Cystic Fibrosis: A Review of Clinical Effectiveness Intranasal Corticosteroids for the Management of Chronic Rhinosinusitis or Nasal Polyposis in Cystic Fibrosis: A Review of Clinical Effectiveness | CADTH.ca Find the information you need Intranasal Corticosteroids for the Management of Chronic Rhinosinusitis or Nasal Polyposis in Cystic Fibrosis: A Review of Clinical Effectiveness Intranasal

2019 Canadian Agency for Drugs and Technologies in Health - Rapid Review

66. Psoriasis patients’ experiences concerning medical adherence to treatment with topical corticosteroids (PubMed)

Psoriasis patients’ experiences concerning medical adherence to treatment with topical corticosteroids Nonadherence to topical treatment of psoriasis is a common cause of treatment failure. This focus group study was conducted to obtain the patients' own experiences and explanations regarding medical adherence. The participants consisted of eight primary adherent patients with moderate psoriasis treated with corticosteroid or corticosteroid-calcipotriol combinations, purposefully sampled (...) in the prescriber, diverging information from health care personnel, experiencing side effects, having fear of side effects, impractical formulations of topical products, and impatience regarding time before an effect of the treatment was observed. From this study, the recommendations for the prescribing doctor to improve medical adherence are, the doctor needs to take time to listen to the patient, prescribe a topical product that is easy to apply and less greasy, inform the patients about benefits from

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2016 Psoriasis (Auckland, N.Z.)

67. Bioequivalence Methodologies for Topical Drug Products: In Vitro and Ex Vivo Studies with a Corticosteroid and an Anti-Fungal Drug (PubMed)

Bioequivalence Methodologies for Topical Drug Products: In Vitro and Ex Vivo Studies with a Corticosteroid and an Anti-Fungal Drug To examine whether in vitro and ex vivo measurements of topical drug product performance correlate with in vivo outcomes, such that more efficient experimental approaches can be reliably and reproducibly used to establish (in)equivalence between formulations for skin application.In vitro drug release through artificial membranes, and drug penetration into porcine (...) vivo did not parallel that in vivo, presumably due to the absence of a functioning microcirculation. In vitro release of BMV from the different formulations did not overlap with either ex vivo or in vivo tape-stripping data whereas, for EN, a good correlation was observed. No measurable permeation of either BMV or EN was detected in a 6-h in vitro skin penetration experiment.In vitro and ex vivo methods for topical bioequivalence determination can show correlation with in vivo outcomes. However

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2017 Pharmaceutical research

68. The use of topical corticosteroides in the treatment of oral lichen planus in Spain: A national survey (PubMed)

The use of topical corticosteroides in the treatment of oral lichen planus in Spain: A national survey Explore the treatment of oral lichen planus with topical corticosteroids by the healthcare professionals in Spain.A questionnaire targeted health professionals who treat OLP, in particular maxillofacial surgeons, dermatologist and dentist. The dissemination of the questionnaires was conducted through professional associations and dental and medical societies. The questionnaire was previously (...) evaluated by means of a cognitive pre-test procedure to ensure that the questions were opportune and appropriate, understandable and accep-table among the professionals.Of the 890 questionnaires sent a total of 190 questionnaires were answered by 90 dentists, 60 dermatologists and 40 by maxillofacial surgeons. The most frequent treatment was 0.1%triamcinolone acetonide in orobase 3 times a day. The effectiveness of the topical corticosteroid treatment was 6.68 (SD= 2.26) in a scale of 1 to 10. The 30

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2017 Medicina oral, patología oral y cirugía bucal

69. Topical corticosteroid phobia in parents of pediatric patients with atopic dermatitis: a multicentre survey (PubMed)

Topical corticosteroid phobia in parents of pediatric patients with atopic dermatitis: a multicentre survey Families of children affected with atopic dermatitis (AD) often report fear and anxiety regarding treatment with topical corticosteroids (TCS), which may lead to reduced compliance. The objective of our study was to measure, through a standardized questionnaire, fear of TCS in families of pediatric patients with AD and to identify items associated with fear.Families of pediatric patients (...) with AD were enrolled in 9 Italian centers of pediatric dermatology. Enrolled parents were invited to fill in a questionnaire including questions on sociodemographic and clinical characteristics and 3 sets of questions on corticosteroid phobia (general fear, specific fears, behaviours regarding TCS). Determinants of the level of general fear were investigated through multivariable analysis.A total of 300 outpatients with AD were enrolled. Most parents (80%) had a high instruction level. Eighty-one

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2017 Italian journal of pediatrics

70. Misuse of topical corticosteroids on facial skin. A study of 200 patients. (PubMed)

Misuse of topical corticosteroids on facial skin. A study of 200 patients. Topical corticosteroids have become available as over the counter drugs and are widely misused for various conditions.The aim of this study is to assess the clinical and epidemiological aspects of the unjustified use of topical corticosteroids for facial skin.A total of 200 patients with facial dermatoses and topical corticosteroid misapplication daily over face for not less than 30 days were included in the study (...) . This was a prospective study conducted in a tertiary care dermatology outpatient centre of the Jammu region. A detailed clinical history regarding topical corticosteroid use was taken and adverse effects analysed.A total of 166 patients were women and 34 were men. The predominant age was 31-40 years. A total of 170 patients (85%) were in the age group of 21-50 years. Duration of application was over 1 month up to 3 years, daily. Betamethasone or clobetasol ointments were used in 75 patients (37.5%) and momatasone

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2017 Journal of dermatological case reports

71. Xerostomia and Salivary Gland Hypofunction in Patients with Oral Lichen Planus Before and After Treatment with Topical Corticosteroids (PubMed)

Xerostomia and Salivary Gland Hypofunction in Patients with Oral Lichen Planus Before and After Treatment with Topical Corticosteroids Oral lichen planus and mouth dryness are common pathoses, yet not entirely understood. These two conditions may be associated, with a few studies investigating the relationship between mouth dryness and oral lichen planus providing conflicting results. None of the studies have explored the specific impact of disease treatment on mouth dryness.The purpose (...) of this observational before and after comparison study was to examine the effect of treatment of oral lichen planus with topical corticosteroids on mouth dryness.Nineteen subjects with oral lichen planus were evaluated for the severity of xerostomia using a xerostomia inventory and a visual analogue scale. Stimulated and unstimulated whole salivary flow rates, unstimulated salivary pH and buffering capacity were also measured. All subjects were evaluated before and after treatment with topical corticosteroids.All

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2017 The open dentistry journal

72. Topical corticosteroids knowledge, attitudes, and practices of primary care physicians (PubMed)

Topical corticosteroids knowledge, attitudes, and practices of primary care physicians To assess knowledge, attitudes, and practices of primary care physicians (PCPs) toward topical corticosteroids (TCs). Methods: A cross-sectional, 53-item questionnaire based study on TCs was conducted among PCPs in Riyadh, Kingdom of Saudi Arabia between January and March 2015. A maximum score of 30 was calculated for the knowledge portion. Results: Out of 420 PCPs, 336 responded (80%). Most participants

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2017 Saudi medical journal

73. Efficacy and Safety of Topical Corticosteroids for Management of Oral Chronic Graft versus Host Disease (PubMed)

Efficacy and Safety of Topical Corticosteroids for Management of Oral Chronic Graft versus Host Disease Oral chronic graft versus host disease (cGVHD) is a major complication in transplantation community, a problem that can be addressed with topical intervention. Topical corticosteroids are the first line of treatment although the choice remains challenging as none of the available treatments is supported by strong clinical evidence.This systematic review aims to determine the clinical efficacy (...) and safety of topical corticosteroids for the management of the mucosal alterations of oral cGVHD.Electronic search of different databases was conducted: PubMed, Cochrane library, Grey literature, WHO, and clinical trials.gov for clinical trial registration as well as hand search in the references of relevant articles up to November 2016.Extracted pieces of information were intervention, population, sample sizes, and outcomes.Six studies were included: 2 randomized clinical trials (RCTs), 3 cohort

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2017 International journal of dentistry

74. Knowledge, Attitude and Advice-Giving Behaviour of Community Pharmacists Regarding Topical Corticosteroids (PubMed)

Knowledge, Attitude and Advice-Giving Behaviour of Community Pharmacists Regarding Topical Corticosteroids This study examines the relationship between community pharmacists' knowledge, attitudes to information provision and self-reported counselling behaviours in relation to topical corticosteroids and adjunct therapy in atopic eczema. A mixed-methods approach was used whereby data from interviews with community pharmacists were used to design a structured questionnaire that a larger sample (...) of community pharmacists completed anonymously. The questionnaire was completed and returned by 105 pharmacists (36% response rate). Pharmacists showed gaps in their knowledge on the use of topical corticosteroids in atopic eczema but had good understanding on the use of emollients. There was a significant correlation between pharmacists' attitudes to information provision and their self-reported counselling behaviour for most themes except in relation to corticosteroid safety where less advice was given

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2017 Pharmacy: Journal of Pharmacy Education and Practice

75. Misuse of Topical Corticosteroids for Cosmetic Purpose in Antananarivo, Madagascar (PubMed)

Misuse of Topical Corticosteroids for Cosmetic Purpose in Antananarivo, Madagascar This cross-sectional study was conducted in Antananarivo, Madagascar, from June to September 2012. We aim to evaluate the misuse of TC on the face for cosmetic purpose and the adverse effects due to its application. A questionnaire-based analysis was done among females who use topical corticosteroids on the face for cosmetic purpose. Of the 770 women questioned, 384 (49,8%) used topical corticosteroids

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2017 BioMed research international

76. Topical corticosteroid withdrawal in a pediatric patient (PubMed)

Topical corticosteroid withdrawal in a pediatric patient 28932784 2019 02 26 2352-5126 3 5 2017 Sep JAAD case reports JAAD Case Rep Topical corticosteroid withdrawal in a pediatric patient. 420-421 10.1016/j.jdcr.2017.06.006 Dhossche Julie J Department of Dermatology, Oregon Health and Science University, Portland, Oregon. Simpson Eric E Department of Dermatology, Oregon Health and Science University, Portland, Oregon. Hajar Tamar T Department of Dermatology, Oregon Health and Science (...) University, Portland, Oregon. eng Case Reports 2017 09 08 United States JAAD Case Rep 101665210 2352-5126 ED, emergency department TCS, topical corticosteroids atopic dermatitis pediatrics steroid withdrawal syndrome topical corticosteroids 2017 9 22 6 0 2017 9 22 6 0 2017 9 22 6 1 epublish 28932784 10.1016/j.jdcr.2017.06.006 S2352-5126(17)30118-2 PMC5594228 Br Med J. 1968 Mar 2;1(5591):579-80 4231359 J Am Acad Dermatol. 2015 Mar;72(3):541-549.e2 25592622 Br Med J. 1969 Mar 15;1(5645):671-3 4237682 Arch

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2017 JAAD Case Reports

77. Ritonavir and Topical Ocular Corticosteroid Induced Cushing's Syndrome in an Adolescent with HIV-1 Infection. (PubMed)

Ritonavir and Topical Ocular Corticosteroid Induced Cushing's Syndrome in an Adolescent with HIV-1 Infection. Cushing's syndrome after topical ocular corticosteroid use is extremely rare. We describe a case of symptomatic Cushing's syndrome in an adolescent male with sight-threatening vernal keratoconjunctivitis on antiretroviral therapy for HIV-1 infection that included ritonavir, a potent cytochrome p450 CYP3A4 inhibitor. CYP3A4 inhibition reduces the metabolism of exogenous corticosteroids

2017 Pediatric Infectious Dsease Journal

78. Change of Oral to Topical Corticosteroid Therapy Exacerbated Glucose Tolerance in a Patient with Plaque Psoriasis (PubMed)

Change of Oral to Topical Corticosteroid Therapy Exacerbated Glucose Tolerance in a Patient with Plaque Psoriasis BACKGROUND Psoriasis is known as the most frequent disease treated by long-term topical steroids. It is also known that patients with thick, chronic plaques require the highest potency topical steroids. However, the treatment is limited to up to four weeks due to risk of systemic absorption. CASE REPORT An 80-year-old man was diagnosed with type 2 diabetes 16 years before (...) , and was being administered insulin combined with alpha glucosidase inhibitor. He was diagnosed with plaque psoriasis and his oral steroid treatment was switched to topical steroid treatment due to lack of improvement and poorly controlled blood glucose level. The hypoglycemic events improved after the psoriatic lesions improved. CONCLUSIONS Control of blood glucose level is difficult at the very beginning of topical steroid treatment for psoriasis especially if a patient is receiving insulin treatment

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2017 The American journal of case reports

79. Topical Corticosteroid Phobia in Atopic Dermatitis: A Systematic Review. (PubMed)

Topical Corticosteroid Phobia in Atopic Dermatitis: A Systematic Review. Topical corticosteroid (TCS) phobia refers to the negative feelings and beliefs related to TCSs experienced by patients and patients' caregivers. This phenomenon may be a major contributing factor in treatment failure in patients with atopic dermatitis, yet it has been sparsely described in the literature.To systematically assess the nomenclature, prevalence, origins, and effect on treatment adherence of TCS phobia (...) the 490 articles identified by literature search, 16 met the eligibility criteria. All studies were cross-sectional. Topical corticosteroid phobia prevalence ranged from 21.0% (95% CI, 15.8%-26.2%) to 83.7% (95% CI, 81.9%-85.5%). There was significant variation in how phobia was defined, ranging from concern to irrational fear. Questionnaires used to assess for TCS phobia included 1 to 69 questions. In the 2 studies that compared nonadherence between a phobia group and a nonphobia group, patients

2017 JAMA dermatology

80. Updated evidence-based (S2e) European Dermatology Forum guideline on topical corticosteroids in pregnancy. (PubMed)

Updated evidence-based (S2e) European Dermatology Forum guideline on topical corticosteroids in pregnancy. Topical corticosteroids may be needed for treating skin conditions in pregnancy. Nevertheless, only limited data on the fetal effects of topical corticosteroids are available.To update an evidence-based guideline on the safe use of topical corticosteroids in pregnancy.A guideline subcommittee of the European Dermatology Forum updated the guideline by adding and appraising new evidence.The (...) current best evidence from 14 observational studies with 1 601 515 study subjects found no significant associations between maternal use of topical corticosteroids of any potency and some adverse pregnancy outcomes including mode of delivery, birth defect, preterm delivery and fetal death. However, maternal use of potent/very potent topical corticosteroids, especially in large amounts, is associated with an increase in the risk of low birthweight.Mild/moderate topical corticosteroids should

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2017 Journal of the European Academy of Dermatology and Venereology

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