How to Trip Rapid Review

Step 1: Select articles relevant to your search (remember the system is only optimised for single intervention studies)

Step 2: press

Step 3: review the result, and maybe amend the or if you know better! If we're unsure of the overall sentiment of the trial we will display the conclusion under the article title. We then require you to tell us what the correct sentiment is.

28,528 results for

Topical Corticosteroid

by
...
Latest & greatest
Alerts

Export results

Use check boxes to select individual results below

SmartSearch available

Trip's SmartSearch engine has discovered connected searches & results. Click to show

61. Systematic review: adrenal insufficiency secondary to swallowed topical corticosteroids in eosinophilic oesophagitis. Full Text available with Trip Pro

Systematic review: adrenal insufficiency secondary to swallowed topical corticosteroids in eosinophilic oesophagitis. Swallowed topical corticosteroids are prescribed for eosinophilic oesophagitis (EoE), but there is a theoretical risk of adrenal insufficiency from their use.To determine if the use of topical corticosteroids to treat EoE is associated with the development of adrenal insufficiency.We conducted a systematic review of the published literature from January 1, 1950 to April 1, 2017 (...) using Pubmed, Embase, Web of Science and Cochrane Central. Studies and meeting abstracts were included that described patients with EoE who received swallowed topical corticosteroids and any investigation for adrenal insufficiency.The search revealed 1610 unique publications, and 17 met inclusion criteria. There were 7 randomised controlled trials (RCTs), 6 prospective observational studies, 3 retrospective observational studies, and 1 case report. Cortisol measurements were performed on 596

2018 Alimentary Pharmacology & Therapeutics

62. A Study to Evaluate Upadacitinib in Combination With Topical Corticosteroids in Adolescent and Adult Participants With Moderate to Severe Atopic Dermatitis

A Study to Evaluate Upadacitinib in Combination With Topical Corticosteroids in Adolescent and Adult Participants With Moderate to Severe Atopic Dermatitis A Study to Evaluate Upadacitinib in Combination With Topical Corticosteroids in Adolescent and Adult Participants With Moderate to Severe Atopic Dermatitis - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record (...) Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. A Study to Evaluate Upadacitinib in Combination With Topical Corticosteroids in Adolescent and Adult Participants With Moderate to Severe Atopic Dermatitis (AD Up) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal

2018 Clinical Trials

63. A Randomized Trial of Topical Corticosteroid Use in Addition to Oral Antivirals for Prevention of Recurrence of Herpes Simplex Virus (HSV) Keratitis

A Randomized Trial of Topical Corticosteroid Use in Addition to Oral Antivirals for Prevention of Recurrence of Herpes Simplex Virus (HSV) Keratitis A Randomized Trial of Topical Corticosteroid Use in Addition to Oral Antivirals for Prevention of Recurrence of Herpes Simplex Virus (HSV) Keratitis - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved (...) Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. A Randomized Trial of Topical Corticosteroid Use in Addition to Oral Antivirals for Prevention of Recurrence of Herpes Simplex Virus (HSV) Keratitis The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical

2018 Clinical Trials

64. Potency of Topical Corticosteroids in Combination Preparations

Potency of Topical Corticosteroids in Combination Preparations Potency of Topical Corticosteroids in Combination Preparations - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Potency of Topical (...) University of the Negev Collaborator: Soroka University Medical Center Information provided by (Responsible Party): Alex Zvulunov, Ben-Gurion University of the Negev Study Details Study Description Go to Brief Summary: Several combination topical drugs are available on the market. The potency of corticosteroids depends on a particular molecular structure and the skin penetration properties. Besides molecular structure, a penetration of a corticosteroid molecule correlates with physical properties

2018 Clinical Trials

65. Study of the Efficacy of 532nm Laser and 1064 nm Laser in the Treatment of Cutaneous Lupus Erythematous Versus Topical Corticosteroids Alone

Study of the Efficacy of 532nm Laser and 1064 nm Laser in the Treatment of Cutaneous Lupus Erythematous Versus Topical Corticosteroids Alone Study of the Efficacy of 532nm Laser and 1064 nm Laser in the Treatment of Cutaneous Lupus Erythematous Versus Topical Corticosteroids Alone - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save (...) this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Study of the Efficacy of 532nm Laser and 1064 nm Laser in the Treatment of Cutaneous Lupus Erythematous Versus Topical Corticosteroids Alone The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your

2018 Clinical Trials

66. A cohort study on the risk of lymphoma and skin cancer in users of topical tacrolimus, pimecrolimus, and corticosteroids (Joint European Longitudinal Lymphoma and Skin Cancer Evaluation – JOELLE study) Full Text available with Trip Pro

A cohort study on the risk of lymphoma and skin cancer in users of topical tacrolimus, pimecrolimus, and corticosteroids (Joint European Longitudinal Lymphoma and Skin Cancer Evaluation – JOELLE study) There is a concern that topical tacrolimus and pimecrolimus, indicated for second-line treatment of atopic dermatitis, may increase the risk of lymphoma and skin cancer, particularly in children.The aim of this study was to compare incidence rates (IRs) of lymphoma and skin cancer between new (...) users of topical tacrolimus or pimecrolimus and users of moderate- to high-potency topical corticosteroids (TCSs) and untreated subjects.This is a multicenter cohort study with frequency matching by strata of propensity scores in population databases in the Netherlands, Denmark, Sweden, and the UK. IR ratios (IRRs) were estimated using Mantel-Haenszel methods for stratified analysis.We included 19,948 children and 66,127 adults initiating tacrolimus, 23,840 children and 37,417 adults initiating

2018 Clinical epidemiology

67. A Long-term Study of Baricitinib (LY3009104) With Topical Corticosteroids in Adults With Moderate to Severe Atopic Dermatitis That Are Not Controlled With Cyclosporine or for Those Who Cannot Take Oral Cyclosporine Because it is Not Medically Advisable

A Long-term Study of Baricitinib (LY3009104) With Topical Corticosteroids in Adults With Moderate to Severe Atopic Dermatitis That Are Not Controlled With Cyclosporine or for Those Who Cannot Take Oral Cyclosporine Because it is Not Medically Advisable A Long-term Study of Baricitinib (LY3009104) With Topical Corticosteroids in Adults With Moderate to Severe Atopic Dermatitis That Are Not Controlled With Cyclosporine or for Those Who Cannot Take Oral Cyclosporine Because it is Not Medically (...) Advisable - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. A Long-term Study of Baricitinib (LY3009104) With Topical Corticosteroids in Adults With Moderate to Severe Atopic Dermatitis That Are Not Controlled

2018 Clinical Trials

68. Diode Laser Versus Topical Corticosteroids in Management of Oral Ulcers in Behcet's Disease

Diode Laser Versus Topical Corticosteroids in Management of Oral Ulcers in Behcet's Disease Diode Laser Versus Topical Corticosteroids in Management of Oral Ulcers in Behcet's Disease - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more (...) studies before adding more. Diode Laser Versus Topical Corticosteroids in Management of Oral Ulcers in Behcet's Disease (BD) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03771768 Recruitment Status : Not yet recruiting

2018 Clinical Trials

69. Tralokinumab in Combination With Topical Corticosteroids in Subjects With Severe Atopic Dermatitis Who Are Not Adequately Controlled With or Have Contraindications to Oral Cyclosporine A

Tralokinumab in Combination With Topical Corticosteroids in Subjects With Severe Atopic Dermatitis Who Are Not Adequately Controlled With or Have Contraindications to Oral Cyclosporine A Tralokinumab in Combination With Topical Corticosteroids in Subjects With Severe Atopic Dermatitis Who Are Not Adequately Controlled With or Have Contraindications to Oral Cyclosporine A - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration (...) or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Tralokinumab in Combination With Topical Corticosteroids in Subjects With Severe Atopic Dermatitis Who Are Not Adequately Controlled With or Have Contraindications to Oral Cyclosporine A (ECZTRA 7) The safety and scientific validity of this study is the responsibility of the study sponsor

2018 Clinical Trials

70. A prospective, randomized clinical study comparing drug eluting stent therapy and intranasal corticoid steroid therapy in the treatment of patients with chronic rhinosinusitis. (Abstract)

A prospective, randomized clinical study comparing drug eluting stent therapy and intranasal corticoid steroid therapy in the treatment of patients with chronic rhinosinusitis. To conduct the first prospective, randomized controlled clinical trial comparing the efficacy of a drug-eluting stent (DES) (the Relieva StratusTM MicroFlow Spacer) and topical intranasal corticosteroid therapy in patients with chronic rhinosinusitis (CRS).Sixty-three adult patients with ethmoiditis were randomized (...) in the nasal spray group, but in the DES group a significant difference was noted only at three months. There was a statistically significant increase in total nasal cavity volumes in the corticosteroid spray group, but not in the DES group.We found that patients benefitted from DES and the corticosteroid nasal spray. We could not find any significant difference between the treatments, except the greater increase in the total nasal cavity volumes favouring the nasal spray group. Because of the very good

2017 Rhinology Controlled trial quality: uncertain

71. Analysis of Inhaled Corticoid Prescriptions in General Medicine

the rate of consultations where all the elements required for guiding the prescription of an inhaled corticoid are available. The secondary objectives are: Identify other factors associated with decision-making Identify the causes of inhaled corticosteroid stopping (de-prescription) Condition or disease Asthma Chronic Obstructive Pulmonary Disease Study Design Go to Layout table for study information Study Type : Observational Estimated Enrollment : 80 participants Observational Model: Case-Only Time (...) Perspective: Cross-Sectional Official Title: Analysis of Inhaled Corticoid Prescriptions in General Medicine Actual Study Start Date : July 13, 2017 Actual Primary Completion Date : July 1, 2018 Estimated Study Completion Date : December 31, 2018 Resource links provided by the National Library of Medicine related topics: Groups and Cohorts Go to Group/Cohort Study population Adults consulting with one of the participating general practitioners and requiring long term inhaled corticoids and monitoring

2017 Clinical Trials

72. Association of Topical Corticosteroid Use and Bone Mineral Density in Patients with Atopic Dermatitis

Association of Topical Corticosteroid Use and Bone Mineral Density in Patients with Atopic Dermatitis "Association of Topical Corticosteroid Use and Bone Mineral Density in " by Carsten Paulson < > > > > > Title Author Date of Graduation Summer 8-8-2015 Degree Type Capstone Project Degree Name Master of Science in Physician Assistant Studies First Advisor Annjanette Sommers, PA-C, MS Rights . Abstract Background Atopic dermatitis (AD) is a common pruritic inflammatory skin disease. First-line (...) therapy for AD involves the use of topical corticosteroids. With long-term use, these agents exert systemic effects and have been associated with adverse effects on bone health. This review assesses the current evidence for an association between topical corticosteroid use and bone mineral density in patients with atopic dermatitis. Methods An exhaustive search of available literature was conducted in using the MEDLINE-Ovid, Web of Science, CINAHL, and Evidence-Based Medicine Reviews Multifile

2015 Pacific University EBM Capstone Project

73. High-dose inhaled corticosteroids in asthma

High-dose inhaled corticosteroids in asthma Asthma: medicines safety priorities Asthma: medicines safety priorities Key therapeutic topic Published: 15 January 2015 nice.org.uk/guidance/ktt5 pathways K Ke ey points y points Inhaled corticosteroids (ICS) are the first-choice regular preventer therapy for adults, young people and children with asthma. When long-acting beta agonists (LABAs) are prescribed for people with asthma, they should be prescribed with an ICS. LABAs should not be used (...) , including self-monitoring and a follow- up with a healthcare professional. Review and update the person's asthma action plan when decreasing maintenance therapy. Prolonged use of high doses of ICS (as with the use of oral corticosteroids) carries a risk of systemic side effects, including adrenal suppression, growth retardation in children and young people, decreased bone mineral density, cataracts, glaucoma, and psychological or behavioural effects. (See the following links for more details: MHRA 2006

2015 National Institute for Health and Clinical Excellence - Advice

74. Study to Evaluate the Efficacy and Safety of Tezepelumab in Reducing Oral Corticosteroid Use in Adults With Oral Corticosteroid Dependent Asthma

Use in Adults With Oral Corticosteroid Dependent Asthma (SOURCE) Actual Study Start Date : March 5, 2018 Estimated Primary Completion Date : November 26, 2020 Estimated Study Completion Date : November 26, 2020 Resource links provided by the National Library of Medicine related topics: Arms and Interventions Go to Arm Intervention/treatment Experimental: Tezepelumab Tezepelumab subcutaneous injection Biological: Tezepelumab Tezepelumab subcutaneous injection Placebo Comparator: Placebo Placebo (...) Study to Evaluate the Efficacy and Safety of Tezepelumab in Reducing Oral Corticosteroid Use in Adults With Oral Corticosteroid Dependent Asthma Study to Evaluate the Efficacy and Safety of Tezepelumab in Reducing Oral Corticosteroid Use in Adults With Oral Corticosteroid Dependent Asthma - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save

2018 Clinical Trials

75. Corticosteroid(CS) + Lido or Corticosteroid(CS) Alone

: Treatment Official Title: Corticosteroid(CS) Injections for the Treatment of Common Upper Extremity Pathologies, With or Without Lidocaine Estimated Study Start Date : March 2019 Estimated Primary Completion Date : August 2021 Estimated Study Completion Date : August 2021 Resource links provided by the National Library of Medicine related topics: available for: Arms and Interventions Go to Arm Intervention/treatment Active Comparator: Treatment Group (corticosteroid injection plus lidocaine) Treatment (...) Corticosteroid(CS) + Lido or Corticosteroid(CS) Alone Corticosteroid(CS) + Lido or Corticosteroid(CS) Alone - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Corticosteroid(CS) + Lido or Corticosteroid(CS

2018 Clinical Trials

76. A Study Comparing Corticosteroids Alone Versus Corticosteroids and Extracorporal Photopheresis (ECP) as First-line Treatment of Standard II Acute Graft-versus-host Disease

Photopheresis (ECP) as First-line Treatment of Standard Risk Grade II Acute Graft-versus-host Disease After Allogeneic Stem Cell Transplantation Estimated Study Start Date : October 1, 2018 Estimated Primary Completion Date : April 1, 2021 Estimated Study Completion Date : April 1, 2022 Resource links provided by the National Library of Medicine related topics: available for: resources: Arms and Interventions Go to Arm Intervention/treatment Experimental: Experimental group corticosteroids + ECP Combination (...) A Study Comparing Corticosteroids Alone Versus Corticosteroids and Extracorporal Photopheresis (ECP) as First-line Treatment of Standard II Acute Graft-versus-host Disease A Study Comparing Corticosteroids Alone Versus Corticosteroids and Extracorporal Photopheresis (ECP) as First-line Treatment of Standard II Acute Graft-versus-host Disease - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search

2018 Clinical Trials

77. Corticosteroid injections provide only short term relief for rotator cuff disorders

the widespread use of corticosteroid injections, past trials have had mixed findings and their use continues to be debated. The last review on the topic was conducted in 2010, and since then four new trials have been published. What did this study do? This systematic review and meta-analysis identified 11 randomised controlled trials including 726 adults with rotator cuff disorders. One of the trials compared corticosteroid injection with placebo injection of salt water, and the remaining trials compared (...) to treat pain. Despite the widespread use of corticosteroid injections, past trials have had mixed findings and their use continues to be debated. The last review on the topic was conducted in 2010, and since then four new trials have been published. What did this study do? This systematic review and meta-analysis identified 11 randomised controlled trials including 726 adults with rotator cuff disorders. One of the trials compared corticosteroid injection with placebo injection of salt water

2019 NIHR Dissemination Centre

78. Antenatal Corticosteroid Therapy for Fetal Maturation

from repeated courses (especially in the reduction and severity of respiratory distress), there also are animal and human data that suggest deleterious effects on the fetus regarding cerebral myelination, lung growth, and function of the hypothalamic–pituitary–adrenal axis. Follow-up of children at 2 years of age who were exposed to repeat courses of antenatal corticosteroids showed no significant difference in physical or neurocognitive measures in two studies ( , ), and the same outcome was found (...) in younger children in a third study ( ). Although not statistically significant, the relative risk of cerebral palsy in infants exposed to serial courses of antenatal corticosteroids (RR, 5.7; 95% confidence interval, 0.7–46.7; P =.12) in one study is of concern and warrants further study (39). Maternal effects include increased risk of infection and suppression of the hypothalamic–pituitary–adrenal axis ( , ). Regularly scheduled repeat courses or serial courses (more than two) are not currently

2017 American College of Obstetricians and Gynecologists

79. Guidelines for the Diagnosis and Management of Critical Illness-Related Corticosteroid Insufficiency (CIRCI) in Critically Ill Patients (Part I)

): Moderator at Annual Meeting, the European Society of Intensive Care Medicine (EISCM) (co-chair of Corticosteroid Guideline in collaboration with SCCM), and the Korean Society of Critical Care Medicine (co-director and speaker at Multiprofessional Critical Care Board Review Course). He has spoken on the topic of corticosteroid use in critical illness and specifically in sepsis at the International Symposium in Critical and Emergency Medicine in March 2017. Dr. Arlt participates in the Society (...) ACTH (1 μg) stimulation test with total random cortisol for diagnosis of adrenal insufficiency in 59 adults with septic shock ( ). Compared with total random cortisol, the low-dose ACTH test was better able to predict a longer duration of vasopressor requirement and hemodynamic response to corticosteroids . Similarly, prospective cohort studies in adults with or without sepsis ( ) and in patients with multiple trauma ( ) found that patients with CIRCI, i.e., total cortisol levels < 10 μg/dL

2017 Society of Critical Care Medicine

80. Moisturisers improve eczema symptoms and lessen the need for corticosteroids

score, mean difference [MD] -2.42 (95% confidence interval [CI] -4.55 to -0.28; three studies, 276 participants). However, the change was not considered clinically significant. Fewer people using moisturisers had flares, 27% compared to 67% not using moisturisers over six month follow up (risk ratio [RR] 0.40, 95% CI 0.23 to 0.70; two studies, 87 participants). Time between flares was prolonged with moisturisers (median of 180 versus 30 days). Less topical corticosteroids were needed for people (...) to the SCORAD score, mean difference [MD] -2.42 (95% confidence interval [CI] -4.55 to -0.28; three studies, 276 participants). However, the change was not considered clinically significant. Fewer people using moisturisers had flares, 27% compared to 67% not using moisturisers over six month follow up (risk ratio [RR] 0.40, 95% CI 0.23 to 0.70; two studies, 87 participants). Time between flares was prolonged with moisturisers (median of 180 versus 30 days). Less topical corticosteroids were needed

2019 NIHR Dissemination Centre

To help you find the content you need quickly, you can filter your results via the categories on the right-hand side >>>>