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Topical Corticosteroid

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28321. Best evidence topic report. Intra-articular corticosteroid injections in acute rheumatoid monoarthritides. Full Text available with Trip Pro

Best evidence topic report. Intra-articular corticosteroid injections in acute rheumatoid monoarthritides. A short cut review was carried out to establish whether intra-articular corticosteroid injections were effective at reducing pain in patients with acute rheumatoid monoarthritis. Altogether 215 papers were found using the reported search, of which one presented the best evidence to answer the clinical question. The author, date and country of publication, patient group studied, study type

2004 Emergency Medicine Journal

28322. Corticosteroids and Corticosteroid Replacement Therapy

. They are written by UK doctors and based on research evidence, UK and European Guidelines. You may find the article more useful, or one of our other . In this article In This Article Corticosteroids and Corticosteroid Replacement Therapy In this article Hydrocortisone (cortisol) is secreted by the adrenal cortex and has both glucocorticoid and mineralocorticoid effects. The term 'glucocorticoid' derives from the early discovery that these hormones were important in glucose metabolism. Since the 1940s synthetic (...) Corticosteroids and Corticosteroid Replacement Therapy Corticosteroids and Corticosteroid Replacement Therapy | Patient TOPICS Try our Symptom Checker TREATMENT RESOURCES Try our Symptom Checker PROFESSIONAL Upgrade to Patient Pro / / Search Corticosteroids and Corticosteroid Replacement Therapy Authored by , Reviewed by | Last edited 20 Jan 2015 | Certified by This article is for Medical Professionals Professional Reference articles are designed for health professionals to use

2008 Mentor

28323. A comparison of oral and topical corticosteroids in patients with bullous pemphigoid. (Abstract)

A comparison of oral and topical corticosteroids in patients with bullous pemphigoid. Bullous pemphigoid is the most common autoimmune blistering skin disease of the elderly. Because elderly people have low tolerance for standard regimens of oral corticosteroids, we studied whether highly potent topical corticosteroids could decrease mortality while controlling disease.A total of 341 patients with bullous pemphigoid were enrolled in a randomized, multicenter trial and stratified according (...) to the severity of their disease (moderate or extensive). Patients were randomly assigned to receive either topical clobetasol propionate cream (40 g per day) or oral prednisone (0.5 mg per kilogram of body weight per day for those with moderate disease and 1 mg per kilogram per day for those with extensive disease). The primary end point was overall survival.Among the 188 patients with extensive bullous pemphigoid, topical corticosteroids were superior to oral prednisone (P=0.02). The one-year survival rate

2002 NEJM Controlled trial quality: uncertain

28324. Randomised controlled trial of short bursts of a potent topical corticosteroid versus prolonged use of a mild preparation for children with mild or moderate atopic eczema. Full Text available with Trip Pro

Randomised controlled trial of short bursts of a potent topical corticosteroid versus prolonged use of a mild preparation for children with mild or moderate atopic eczema. To determine whether a three day burst of a potent corticosteroid is more effective than a mild preparation used for seven days in children with mild or moderate atopic eczema.Randomised, double blind, parallel group study of 18 weeks' duration.13 general practices and a teaching hospital in the Nottingham area.174 children (...) improvements in disease severity and quality of life compared with baseline.A short burst of a potent topical corticosteroid is just as effective as prolonged use of a milder preparation for controlling mild or moderate atopic eczema in children.

2002 BMJ Controlled trial quality: predicted high

28325. Effect of sequential applications of topical tacrolimus and topical corticosteroids in the treatment of pediatric atopic dermatitis: An open-label pilot study. (Abstract)

Effect of sequential applications of topical tacrolimus and topical corticosteroids in the treatment of pediatric atopic dermatitis: An open-label pilot study. The efficacy of combination therapy with topical corticosteroids and tacrolimus in the treatment of atopic dermatitis remains to be established.Our aim was to determine whether a regimen of sequential application of topical corticosteroids and topical tacrolimus is effective in the treatment of pediatric atopic dermatitis. A second goal (...) application of tacrolimus and a topical corticosteroid ointment on weekend days. In the maintenance phase, the corticosteroid ointment was discontinued and 0.03% tacrolimus ointment was applied twice daily for an additional 2 weeks. Daily application of tacrolimus ointment was then discontinued and replaced by an emollient with application of 0.03% tacrolimus ointment only when necessary for an additional 6 weeks. The Eczema Area and Severity Index score, Investigators' Global Assessment, severity

2008 Journal of American Academy of Dermatology

28326. Treatment of Polytraumatisms With Corticoids

Model: Parallel Assignment Masking: Triple (Participant, Care Provider, Investigator) Primary Purpose: Prevention Official Title: Interest of Treatment of Polytraumatisms With Corticoids (Hydrocortisone) for Patient With Relative Adrenocortical Insufficiency Study Start Date : November 2006 Actual Primary Completion Date : November 2006 Actual Study Completion Date : July 2009 Resource links provided by the National Library of Medicine related topics: related topics: available for: Arms (...) Treatment of Polytraumatisms With Corticoids Treatment of Polytraumatisms With Corticoids - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Treatment of Polytraumatisms With Corticoids (Hypolyte) The safety

2006 Clinical Trials

28327. Antenatal Corticoid Therapy for Late Preterm Babies

Details Study Description Go to Brief Summary: This study aims to determine the effectiveness of antenatal corticosteroid therapy in late preterm babies. The investigators hypothesis is corticoid accelerates fetal lung maturation even after 34 weeks and reduces risk of respiratory distress syndrome and other neonatal morbidities. Condition or disease Intervention/treatment Phase Hyaline Membrane Disease Transient Tachypnea Drug: Betamethasone Not Applicable Detailed Description: Late preterm babies (...) have important morbidity when compared with term babies, with oxygen requirement and more days of hospitalization. If antenatal corticosteroid therapy is necessary for fetal lung maturation after 34 weeks, it remains to be established. The systematic review with metanalysis in Cochrane Library includes a small number of late preterm babies and no conclusion about effectiveness of corticoid therapy in this setting could be drawn. Our hypothesis is that antenatal corticosteroid therapy is effective

2008 Clinical Trials

28328. Treatment With Recombinant Human Growth Hormone (GH) in Children With Short Stature Secondary to a Long Term Corticoid Therapy

Treatment With Recombinant Human Growth Hormone (GH) in Children With Short Stature Secondary to a Long Term Corticoid Therapy Treatment With Recombinant Human Growth Hormone (GH) in Children With Short Stature Secondary to a Long Term Corticoid Therapy - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached (...) the maximum number of saved studies (100). Please remove one or more studies before adding more. Treatment With Recombinant Human Growth Hormone (GH) in Children With Short Stature Secondary to a Long Term Corticoid Therapy The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT00174187 Recruitment Status

2005 Clinical Trials

28329. [Treatment of bullous pemphigoid: general corticosteroid therapy or local corticosteroid therapy?]. (Abstract)

corticothérapie locale? France Ann Dermatol Venereol 7702013 0151-9638 0 Adrenal Cortex Hormones VB0R961HZT Prednisone IM N Ann Dermatol Venereol. 1999 Jan;126(1):13-6 10095883 Administration, Oral Administration, Topical Adrenal Cortex Hormones administration & dosage adverse effects Humans Pemphigoid, Bullous drug therapy Prednisone administration & dosage adverse effects Treatment Outcome 1999 3 30 1999 3 30 0 1 1999 3 30 0 0 ppublish 10095882 MDOI-AD-01-1999-126-1-0151-9638-101019-ART3 (...) [Treatment of bullous pemphigoid: general corticosteroid therapy or local corticosteroid therapy?]. 10095882 1999 06 03 2013 11 21 0151-9638 126 1 1999 Jan Annales de dermatologie et de venereologie Ann Dermatol Venereol [Treatment of bullous pemphigoid: general corticosteroid therapy or local corticosteroid therapy?]. 11-2 Verret J L JL fre Clinical Trial Comment Comparative Study Editorial Randomized Controlled Trial Traitement de la pemphigoïde bulleuse: corticothérapie générale ou

1999 Annales de dermatologie et de venereologie Controlled trial quality: uncertain

28330. Detection of contact hypersensitivity to corticosteroids in allergic contact dermatitis patients who do not respond to topical corticosteroids. (Abstract)

Detection of contact hypersensitivity to corticosteroids in allergic contact dermatitis patients who do not respond to topical corticosteroids. The delayed hypersensitivity development against topical corticosteroids which are used in allergic contact dermatitis (ACD) treatment is an important clinical problem. In our study, 41 ACD patients who did not show any response to topical corticosteroid treatment were patch tested with corticosteroid series and the commercial preparations (...) of corticosteroids and their vehicles. In corticosteroid series, there were budesonide, bethametasone-17-valerate, triamcinolone acetonide, tixocortol pivalate, alclomethasone-17-21-dipropionate, clobetasole-17-propionate, dexamethasone-21-phosphate disodium and hydrocortisone-17-butyrate. We detected positive reaction to corticosteroids in 9 of our cases (22%) (5 single and 4 multiple). The sensitivity was mostly produced by tixocortol pivalate (6 patients). This was followed by triamcinolone acetonide (2

2005 Contact Dermatitis

28331. Addition of a topically applied corticosteroid to a modified Goeckerman regimen for treatment of psoriasis: effect on duration of remission. (Abstract)

Addition of a topically applied corticosteroid to a modified Goeckerman regimen for treatment of psoriasis: effect on duration of remission. A double-blind parallel group study was undertaken to assess the effect of adding a topically applied corticosteroid cream to a modified Goeckerman regimen to treat patients with psoriasis. Nineteen patients with psoriasis were treated with either this regimen and hydrocortisone valerate cream or the regimen and vehicle cream. Patients were given daily

1986 Journal of the American Academy of Dermatology

28332. Treatment of bullous pemphigoid with topical corticosteroids: review of a randomized controlled trial. (Abstract)

Treatment of bullous pemphigoid with topical corticosteroids: review of a randomized controlled trial. 12224989 2002 10 16 2008 03 17 0003-987X 138 9 2002 Sep Archives of dermatology Arch Dermatol Treatment of bullous pemphigoid with topical corticosteroids: review of a randomized controlled trial. 1236-7 Gelfand Joel M JM Department of Dermatology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA. Werth Victoria P VP eng Comment Editorial United States Arch Dermatol

2002 Archives of Dermatology Controlled trial quality: uncertain

28333. The addition of topical doxepin to corticosteroid therapy: an improved treatment regimen for atopic dermatitis. (Abstract)

Phillips S S Sulica V I VI Bernstein J E JE eng Clinical Trial Journal Article Multicenter Study Randomized Controlled Trial England Int J Dermatol 0243704 0011-9059 0 Adrenal Cortex Hormones 0 Antipruritics 1668-19-5 Doxepin 1ZK20VI6TY Triamcinolone WI4X0X7BPJ Hydrocortisone IM Administration, Cutaneous Adrenal Cortex Hormones adverse effects therapeutic use Adult Antipruritics administration & dosage adverse effects therapeutic use Dermatitis, Atopic drug therapy Double-Blind Method Doxepin (...) The addition of topical doxepin to corticosteroid therapy: an improved treatment regimen for atopic dermatitis. 10192169 1999 05 20 2013 11 21 0011-9059 38 2 1999 Feb International journal of dermatology Int. J. Dermatol. The addition of topical doxepin to corticosteroid therapy: an improved treatment regimen for atopic dermatitis. 145-8 Berberian B J BJ Department of Dermatology, Georgetown University Medical Center, Washington, DC, USA. Breneman D L DL Drake L A LA Gratton D D Raimir S S SS

1999 International Journal of Dermatology Controlled trial quality: uncertain

28334. Allergy—Important Advances in Clinical Medicine: Topically Applied Corticosteroids and Cromolyn Sodium in Managing Rhinitis Full Text available with Trip Pro

Allergy—Important Advances in Clinical Medicine: Topically Applied Corticosteroids and Cromolyn Sodium in Managing Rhinitis 18749639 2010 06 30 2018 11 13 0093-0415 141 4 1984 Oct The Western journal of medicine West. J. Med. Allergy-important advances in clinical medicine: topically applied corticosteroids and cromolyn sodium in managing rhinitis. 510 Incaudo G A GA eng Journal Article United States West J Med 0410504 0093-0415 1984 10 1 0 0 1984 10 1 0 1 1984 10 1 0 0 ppublish 18749639

1984 Western Journal of Medicine

28335. Effect of topical corticosteroids on seasonally induced increases in nasal mast cells. (Abstract)

Effect of topical corticosteroids on seasonally induced increases in nasal mast cells. 3135013 1988 09 01 2018 11 13 0267-0623 296 6636 1988 Jun 04 British medical journal (Clinical research ed.) Br Med J (Clin Res Ed) Effect of topical corticosteroids on seasonally induced increases in nasal mast cells. 1572-3 Gomez E E Centre for Medical Research, St Bartholomew's Hospital, West Smithfield, London. Clague J E JE Gatland D D Davies R J RJ eng Clinical Trial Journal Article Randomized (...) Controlled Trial Research Support, Non-U.S. Gov't England Br Med J (Clin Res Ed) 8302911 0267-0623 KGZ1SLC28Z Beclomethasone AIM IM Administration, Topical Adult Beclomethasone administration & dosage therapeutic use Female Humans Male Mast Cells drug effects Nasal Mucosa pathology Rhinitis, Allergic, Seasonal drug therapy pathology Seasons 1988 6 4 1988 6 4 0 1 1988 6 4 0 0 ppublish 3135013 PMC2545955 J Allergy. 1968 Mar;41(3):123-39 5238591 J Allergy Clin Immunol. 1985 Sep;76(3):466-72 4031318 Br Med J

1988 British medical journal (Clinical research ed.) Controlled trial quality: uncertain

28336. Additional effect of grenz rays on psoriasis lesions of the scalp treated with topical corticosteroids. (Abstract)

Additional effect of grenz rays on psoriasis lesions of the scalp treated with topical corticosteroids. In a double-blind study comprising 17 patients with symmetrical psoriasis lesions of the scalp, the combination of grenz ray treatment and topical steroid showed a faster clearing than with the topical steroid alone. The results also indicate a longer remission time with the combination therapy compared to grenz rays alone. Therefore both the faster clearing and the longer remission time

1988 Dermatologica

28337. Sicorten: a synthetic corticosteroid for topical treatment of common dermatoses. (Abstract)

Sicorten: a synthetic corticosteroid for topical treatment of common dermatoses. In an open non-comparative trial 247 eczema patients were treated with Sicorten topicals. Sicorten cream yielded good to very good results in 90%, 97% and 100% of the patients suffering from atopic dermatitis, contact dermatitis and seborrhoeic dermatitis, respectively, while Sicorten ointment produced similar results in 97% and 100% of the patients with chronic atopic dermatitis and chronic contact dermatitis

1986 The Journal of international medical research

28338. Tazarotene in combination with topical corticosteroids. (Abstract)

Tazarotene in combination with topical corticosteroids. The use of a topical corticosteroid in combination with tazarotene has theoretic appeal because each drug has a different mechanism of action, and it is therefore likely that combination therapy will offer additive or synergistic effects. For example, the steroid may promote a rapid initial response together with minimization of erythema during the treatment period, and tazarotene may prolong the duration of the therapeutic effect (...) and lower the probability of relapse. The results of a large, controlled clinical trial in which corticosteroids of various potencies were added to tazarotene therapy showed that tazarotene plus a medium- or high potency corticosteroid produced greater and more rapid efficacy, and superior tolerability, than tazarotene plus placebo cream.

1998 Journal of the American Academy of Dermatology

28339. Comparative merits of two topical corticosteroid antimicrobial drugs. (Abstract)

Comparative merits of two topical corticosteroid antimicrobial drugs. The anti-inflammatory and antimicrobial activities of two topical creams, one containing halcinonide, neomycin and nystatin (HNN), and the other betamethasone valerate, gentamicin, iodochlorhydroxyquin and tolnaftate (BGI), were compared in a randomized, parallel study of 154 patients (eighty-seven secondarily infected eczematous dermatoses; sixty-seven cutaneous candidiasis). Repeated clinical assessments showed that the two

1981 The Journal of international medical research Controlled trial quality: uncertain

28340. Halogenation and topical corticosteroids: a comparison between the 17-butyrate esters of hydrocortisone and clobetasone in ointment bases. (Abstract)

Halogenation and topical corticosteroids: a comparison between the 17-butyrate esters of hydrocortisone and clobetasone in ointment bases. Clobetasone butyrate 0.05% (Eumovate), a halogenated topical steroid, was compared with hydrocortison butyrate 0.1% (Locoid) which does not contain any halogen atoms. In the treatment of eczema there was not difference between the preparations, but in that of psoriasis the halogen-containing steriod was significantly more effective. Under normal (...) circumstances neither preparation had any detectable effect on adrenal function, but with large doses under total-body polythene occlusion, circulating cortisol levels were reduced less by the halogenated than by the non-halogenated preparation. Corticosteroids which contain a halogen atom are often considered to cause more adverse effects than the non-halogenated preparations with similar clinical efficacy. This study shows that this cannot be assumed for their ability to suppress cortisol levels.

1981 The British journal of dermatology Controlled trial quality: uncertain

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