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Topical Corticosteroid

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28201. Pharmacokinetics of ophthalmic corticosteroids. Full Text available with Trip Pro

Pharmacokinetics of ophthalmic corticosteroids. 1477046 1993 02 11 2018 11 13 0007-1161 76 11 1992 Nov The British journal of ophthalmology Br J Ophthalmol Pharmacokinetics of ophthalmic corticosteroids. 681-4 McGhee C N CN Tennent Institute of Ophthalmology, Western Infirmary, Glasgow. eng Journal Article Review England Br J Ophthalmol 0421041 0007-1161 0 Glucocorticoids IM Administration, Topical Conjunctiva Eye metabolism Eye Diseases drug therapy metabolism Glucocorticoids administration

1992 The British journal of ophthalmology

28202. Bone density in asthmatic patients taking high dose inhaled beclomethasone dipropionate and intermittent systemic corticosteroids. Full Text available with Trip Pro

Bone density in asthmatic patients taking high dose inhaled beclomethasone dipropionate and intermittent systemic corticosteroids. Asthmatic patients taking low to moderate doses of inhaled topical corticosteroids have been shown to have lower bone density than those taking bronchodilators only. There is little information on bone density in asthmatic patients taking high dose inhaled corticosteroids.Bone mass was studied in three age matched groups of asthmatic patients. These comprised: 17 (...) vertebral bone density. The bone loss is similar in degree to that seen in patients taking high dose inhaled topical corticosteroids and continuous low dose systemic corticosteroids.

1992 Thorax

28203. Intra-articular corticosteroids in septic arthritis: beneficial or barmy? Full Text available with Trip Pro

Intra-articular corticosteroids in septic arthritis: beneficial or barmy? 10777422 2000 04 20 2018 11 30 0003-4967 59 3 2000 Mar Annals of the rheumatic diseases Ann. Rheum. Dis. Intra-articular corticosteroids in septic arthritis: beneficial or barmy? 240 Lane S E SE eng Case Reports Letter Comment England Ann Rheum Dis 0372355 0003-4967 0 Anti-Inflammatory Agents 0 Glucocorticoids 43502P7F0P Methylprednisolone Acetate X4W7ZR7023 Methylprednisolone IM Ann Rheum Dis. 1998 Nov;57(11):687-90 (...) 9924212 Administration, Topical Aged Aged, 80 and over Anti-Inflammatory Agents therapeutic use Arthritis, Infectious drug therapy Female Glucocorticoids Humans Injections, Intra-Articular Male Methylprednisolone analogs & derivatives therapeutic use Methylprednisolone Acetate Middle Aged 2000 4 25 2000 4 25 0 1 2000 4 25 0 0 ppublish 10777422 PMC1753092

2000 Annals of the Rheumatic Diseases

28204. Role of corticosteroids in cystic fibrosis lung disease. Full Text available with Trip Pro

Role of corticosteroids in cystic fibrosis lung disease. 8778452 1996 09 19 2018 11 13 0141-0768 89 Suppl 27 1996 Journal of the Royal Society of Medicine J R Soc Med Role of corticosteroids in cystic fibrosis lung disease. 8-13 Balfour-Lynn I M IM Respiratory Unit, Great Ormond Street Hospital for Children NHS Trust, London, England. Dinwiddie R R eng Journal Article Review England J R Soc Med 7802879 0141-0768 0 Adrenal Cortex Hormones IM Administration, Inhalation Administration, Oral (...) Adolescent Adrenal Cortex Hormones administration & dosage therapeutic use Adult Aged Bacterial Infections complications Cystic Fibrosis complications pathology Humans Middle Aged Neutrophils Pneumonia prevention & control Randomized Controlled Trials as Topic 37 1996 1 1 1996 1 1 0 1 1996 1 1 0 0 ppublish 8778452 PMC1295619 Pediatr Res. 1982 May;16(5):354-6 7048230 Thorax. 1994 Dec;49(12):1185-8 7878549 J Pediatr. 1984 May;104(5):695-9 6716217 Lancet. 1985 Sep 28;2(8457):686-8 2863676 Thorax. 1986 Jan

1996 Journal of the Royal Society of Medicine

28205. Corticosteroids in the management of croup. Full Text available with Trip Pro

Corticosteroids in the management of croup. 8949336 1997 01 08 2018 11 13 0960-1643 46 409 1996 Aug The British journal of general practice : the journal of the Royal College of General Practitioners Br J Gen Pract Corticosteroids in the management of croup. 493-4 Whelan T R TR eng Letter England Br J Gen Pract 9005323 0960-1643 0 Anti-Inflammatory Agents 0 Glucocorticoids 0 Pregnenediones 51333-22-3 Budesonide IM Administration, Topical Anti-Inflammatory Agents therapeutic use Budesonide Child

1996 The British Journal of General Practice

28206. Echographic evaluation of corticosteroid inhibition of allergic patch test reactions. (Abstract)

Echographic evaluation of corticosteroid inhibition of allergic patch test reactions. 1505193 1992 09 24 2016 11 23 0105-1873 26 3 1992 Mar Contact dermatitis Contact Derm. Echographic evaluation of corticosteroid inhibition of allergic patch test reactions. 212-3 Seidenari S S Department of Dermatology, University of Modena, Italy. Di Nardo A A eng Clinical Trial Journal Article Randomized Controlled Trial England Contact Dermatitis 7604950 0105-1873 0 Allergens 0 Anti-Inflammatory Agents 0 (...) Glucocorticoids IM Administration, Topical Allergens immunology Anti-Inflammatory Agents adverse effects Dermatitis, Contact diagnostic imaging etiology Female Glucocorticoids Humans Patch Tests Ultrasonography 1992 3 1 1992 3 1 0 1 1992 3 1 0 0 ppublish 1505193

1992 Contact Dermatitis Controlled trial quality: uncertain

28207. [Corticosteroid--effects of beclomethasone dipropionate 800 micrograms/day]. (Abstract)

[Corticosteroid--effects of beclomethasone dipropionate 800 micrograms/day]. The effects of beclomethasone dipropionate (BD) 800 micrograms on steroid-dependent adult asthmatics were examined. The study consisted of two groups; 20 patients on 800 micrograms and another 20 patients on 400 micrograms. In addition, 800 micrograms was administered to an additional 12 patients receiving 400 micrograms with insufficient effects. After two weeks of observation period, BD was administered for 12 weeks (...) . Considerable efficacy was also observed in patients whose dosage had been increased from 400 micrograms to 800 micrograms. High dose administration usually increases topical side effects such as hoarseness and stomatitis, however the use of spacers was effective in the prophylaxis and treatment of those symptoms.

1991 Nihon Kyōbu Shikkan Gakkai zasshi

28208. Radiation Therapy and High-Dose Corticosteroids in Treating Older Patients With Primary CNS Non-Hodgkin's Lymphoma

Radiation Therapy and High-Dose Corticosteroids in Treating Older Patients With Primary CNS Non-Hodgkin's Lymphoma Radiation Therapy and High-Dose Corticosteroids in Treating Older Patients With Primary CNS Non-Hodgkin's Lymphoma - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number (...) of saved studies (100). Please remove one or more studies before adding more. Radiation Therapy and High-Dose Corticosteroids in Treating Older Patients With Primary CNS Non-Hodgkin's Lymphoma The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT00003278 Recruitment Status : Completed First Posted : January

1999 Clinical Trials

28209. Phase I Study of Corticosteroid Treatment of Ill-Defined Choroidal Neovascularization in Age-Related Macular Degeneration

of Corticosteroid Treatment of Ill-Defined Choroidal Neovascularization in Age-Related Macular Degeneration Study Start Date : July 1997 Study Completion Date : May 2000 Resource links provided by the National Library of Medicine related topics: related topics: resources: Arms and Interventions Go to Outcome Measures Go to Eligibility Criteria Go to Information from the National Library of Medicine Choosing to participate in a study is an important personal decision. Talk with your doctor and family members (...) or Humphrey perimetry taken within 6 months to qualification. No patients with any contraindications to performing the necessary diagnostic studies, especially the use of fluorescein angiography. No patients with known history of untoward complications from corticosteroid therapy, including elevated intraocular pressure in response to topical or periocular corticosteroids. No patients with medical problems which make consistent follow-up over the treatment period unlikely (e.g., stroke, severe MI

1999 Clinical Trials

28210. Efficacy Study of Zenapax in Combination With CellCept, Cyclosporine and Corticosteroids in Heart Transplant

to Assess the Efficacy and Safety of Zenapax in Combination With CellCept, Cyclosporine, and Corticosteroids in Patients Undergoing Cardiac Transplantation. Study Start Date : August 1999 Actual Primary Completion Date : August 2002 Actual Study Completion Date : August 2002 Resource links provided by the National Library of Medicine related topics: available for: Arms and Interventions Go to Arm Intervention/treatment Experimental: Daclizumab Daclizumab will be administered as a intravenous dose of 1 (...) Efficacy Study of Zenapax in Combination With CellCept, Cyclosporine and Corticosteroids in Heart Transplant A Study to Evaluate the Efficacy and Safety of Zenapax in Combination With CellCept, Cyclosporine, and Corticosteroids in Patients Undergoing Cardiac Transplantation - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study

2002 Clinical Trials

28211. Evaluation of Various Doses of Ro 27-2771 (Test Drug) in Asthmatic Patients Not Treated With Inhaled Corticosteroids

Evaluation of Various Doses of Ro 27-2771 (Test Drug) in Asthmatic Patients Not Treated With Inhaled Corticosteroids Evaluation of Various Doses of Ro 27-2771 (Test Drug) in Asthmatic Patients Not Treated With Inhaled Corticosteroids - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number (...) of saved studies (100). Please remove one or more studies before adding more. Evaluation of Various Doses of Ro 27-2771 (Test Drug) in Asthmatic Patients Not Treated With Inhaled Corticosteroids The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT00048009 Recruitment Status : Completed First Posted

2002 Clinical Trials

28212. Inhaled Corticosteroid Replacement Study

Inhaled Corticosteroid Replacement Study Inhaled Corticosteroid Replacement Study - Efficacy and Safety of Ro 27-2441 (Test Drug) in Moderate Persistent Asthma - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more (...) . Inhaled Corticosteroid Replacement Study - Efficacy and Safety of Ro 27-2441 (Test Drug) in Moderate Persistent Asthma The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT00048022 Recruitment Status : Completed First Posted : October 25, 2002 Last Update Posted : June 19, 2017 Sponsor: Hoffmann-La Roche

2002 Clinical Trials

28213. Therapy of infected dermatitis: comparative response to two corticosteroid antimicrobial creams. (Abstract)

Therapy of infected dermatitis: comparative response to two corticosteroid antimicrobial creams. In a double-blind, parallel trial which lasted 1 week and comprised eighty-eight patients, a study of the response to topical therapy of the infected component of four common eczematous processes showed that the treatment outcome with corticosteroid antimicrobial creams was not influenced by the type of dermatitis. The cream with fluocinonide 0.05% was significantly better than the cream

1980 Journal of the American Academy of Dermatology

28214. The use of a corticosteroid cream for immediate reduction in the clinical signs of acne vulgaris. (Abstract)

The use of a corticosteroid cream for immediate reduction in the clinical signs of acne vulgaris. A controlled trial of the anti-inflammatory effect of a steroid cream (clobetasol propionate) in 11 patients with moderate acne was assessed over a 3 week period. The placebo cream was the base of the steroid cream. Therapeutic effect was assessed by the number of active and less actively inflamed papules and pustules present at the beginning and end of the 3 week trial period. No significant (...) change in lesion counts was observed. This result indicates that a potent topical steroid cream produces no short-term improvement in patients with moderate acne.

1989 Acta dermato-venereologica

28215. An assessment of the relationship between vasoconstrictor assay findings, clinical efficacy and skin thinning effects of a variety of undiluted and diluted corticosteroid preparations. (Abstract)

An assessment of the relationship between vasoconstrictor assay findings, clinical efficacy and skin thinning effects of a variety of undiluted and diluted corticosteroid preparations. We have evaluated a number of diluted and undiluted topical corticosteroid preparations in terms of vasoconstrictor potency, clinical efficacy and skin thinning effects. We conclude that, for the materials tested so far, an area under the curve measurement obtained from serial readings of the vasoconstrictor (...) assay allows reasonably accurate predictions to be made concerning the relative clinical efficacy and skin thinning potential of these agents. If further work with a wide range of topical corticosteroids confirms our findings, the value of the vasoconstrictor assay as a predictive model will be enhanced.

1984 The British journal of dermatology

28216. [Effects of locally administered corticosteroids on mineral metabolism]. (Abstract)

[Effects of locally administered corticosteroids on mineral metabolism]. The author performed a prospective study to test the mineralocorticoid activity of high doses of topically applied corticosteroids. Eight patients were treated with prednisolone eye drops. Twelve patients received fluorhydrocortisone, 9 patients triamcinolone acetonide and 11 dexamethasone; subconjunctival or parabulbar injections were used in all cases. Only the patients treated with fluorhydrocortisone showed (...) a mineralocorticoid effect, i.e., reduced sodium excretion and a high potassium waste in the urine together with a decrease in serum potassium. Fluorhydrocortisone must not be applied topically because the risk of hypokalemia involved is so great.

1984 Klinische Monatsblatter fur Augenheilkunde Controlled trial quality: uncertain

28217. Nasal respiratory resistance and head posture: effect of intranasal corticosteroid (Budesonide) in children with asthma and perennial rhinitis. (Abstract)

Nasal respiratory resistance and head posture: effect of intranasal corticosteroid (Budesonide) in children with asthma and perennial rhinitis. The influence of mouth breathing on craniofacial development has previously been demonstrated. Recent investigations do indicate, however, that head posture also might be related to craniofacial morphology. The aim of the present study was to analyze the effect of a topical steroid spray (Budesonide) on nasal respiratory resistance and head posture

1983 American journal of orthodontics Controlled trial quality: uncertain

28218. Short- and long-term effects of postoperative corticosteroids on trabeculectomy. (Abstract)

Short- and long-term effects of postoperative corticosteroids on trabeculectomy. All patients with primary open-angle or primary angle-closure glaucoma requiring trabeculectomy between January 1982 and January 1983 were entered into a randomized prospective study to evaluate the effect of postoperative corticosteroids. Twenty-three eyes in Group 1 received a cycloplegic and topical antibiotic. Twenty-nine eyes in Group 2 received the same treatment, with the addition of topical 1% prednisolone (...) acetate. Twenty-three eyes in Group 3 received the same treatment as Group 2, with the addition of systemic prednisone. Success rate was significantly improved with the use of topical corticosteroids. Systemic steroids did not prove to be of any added benefit over topical use alone.

1985 Ophthalmology Controlled trial quality: uncertain

28219. Corticosteroids in corneal graft rejection. Oral versus single pulse therapy. (Abstract)

Corticosteroids in corneal graft rejection. Oral versus single pulse therapy. Forty-eight patients with corneal grafts with severe endothelial rejection were randomly assigned to two treatment groups. One group of 24 patients received prednisolone acetate 1% drops hourly and a single intravenous pulse of 500 mg methylprednisolone. The other group of 24 patients received the same topical therapy plus oral prednisone 60 to 80 mg daily. Nineteen (79.2%) grafts survived in the group that received

1991 Ophthalmology Controlled trial quality: uncertain

28220. Intrinsic potencies of novel thiol ester corticosteroids RS-85095 and RS-21314 as compared with clobetasol 17-propionate and fluocinonide. (Abstract)

Intrinsic potencies of novel thiol ester corticosteroids RS-85095 and RS-21314 as compared with clobetasol 17-propionate and fluocinonide. The intrinsic potencies of two novel topical thiol ester corticosteroids, RS-85095 and RS-21314, were compared with the high potency corticosteroids clobetasol 17-propionate and fluocinonide, using human vasoconstriction assays. In these assays, four or five concentrations (0.03 to 3 mg/L) of the corticosteroids in 95% ethanol (alcohol, USP) were applied (...) to predetermined sites on the forearm of volunteers and were occluded following evaporation of the alcohol. The responses were scored in terms of the presence or absence of vasoconstriction and the degree of vasoconstrictive intensity. No statistically significant difference was found in the intrinsic potencies of RS-85095, RS-21314, and clobetasol 17-propionate, and all three corticosteroids were significantly more potent than fluocinonide.

1989 Archives of Dermatology Controlled trial quality: uncertain

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