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Topical Corticosteroid

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181. Effects of topical corticosteroid administration on intraocular pressure in normal and glaucomatous cats. Full Text available with Trip Pro

Effects of topical corticosteroid administration on intraocular pressure in normal and glaucomatous cats. The objective of this study was to determine the effect of topical corticosteroid (CCS) therapy on intraocular pressure (IOP) in normal cats and cats with primary feline congenital glaucoma (FCG).Five normal and 11 FCG cats were studied in two cohorts.IOP was measured by a single, masked observer, once daily, 3-5 days/week throughout the course of CCS treatment and for up to 11 days after (...) treatment discontinuation. One eye per cat was randomly assigned for treatment twice daily with CCS; balanced salt solution (BSS) applied to the contralateral eye served as a control. Differences between eyes and between weeks of the study period were calculated for each cat. A positive response to CCS was defined as a consistent >15% or >25% higher IOP in the treated relative to control eye in normal and FCG cats, respectively.A total of 8 of 11 FCG cats responded to topical CCS after 1-5 weeks

2016 Veterinary ophthalmology Controlled trial quality: uncertain

182. Topical corticosteroid has no influence on inflammation or efficacy after ingenol mebutate treatment of grade I to III actinic keratoses (AK): A randomized clinical trial. (Abstract)

Topical corticosteroid has no influence on inflammation or efficacy after ingenol mebutate treatment of grade I to III actinic keratoses (AK): A randomized clinical trial. Ingenol mebutate (IngMeb) is approved for treatment of actinic keratoses (AK) and may cause unpredictable local skin responses (LSR).We sought to investigate whether IngMeb-induced LSR, pain, and pruritus could be alleviated with a topical glucocorticoid and, further, to assess efficacy, cosmetic outcome, and patient (...) satisfaction in patients with severe photodamage.In this blinded, randomized controlled clinical trial, patients with multiple AK and field cancerization of the face or scalp were treated in 2 areas with IngMeb (0.015%) daily for 3 days. After finalized IngMeb treatment, 1 area was randomized to receive topical clobetasol propionate (0.05%) twice daily for 4 days. Assessments included LSR (0-24; days 1, 4, 8, 15, 57), pain (0-10) and pruritus (0-3; days 1-15), AK clearance (days 15, 57), and cosmetic

2016 Journal of the American Academy of Dermatology Controlled trial quality: uncertain

183. Proliferative and necrotizing otitis externa in a kitten: successful treatment with intralesional and topical corticosteroid therapy Full Text available with Trip Pro

Proliferative and necrotizing otitis externa in a kitten: successful treatment with intralesional and topical corticosteroid therapy Proliferative and necrotising otitis externa (PNOE) is a very rare disease affecting the ear canals and concave pinnae of kittens. This report describes a 5-month-old cat with PNOE. Histopathological examination confirmed the diagnosis. Treatment was initiated with local injection of methylprednisolone acetate into the lesions. The cat was subsequently treated (...) with clobetasol propionate cream, a potent topical glucocorticoid ointment. The cat showed marked improvement. While topical treatment with tacrolimus, an immunosuppressive agent, is reported to be an effective therapy, to the best of our knowledge, this is the first report to treat PNOE with local corticosteroid therapy.

2016 The Journal of Veterinary Medical Science

184. Spongiotic Trachyonychia Treated with Topical Corticosteroids Using the Paper Tape Occlusion Method Full Text available with Trip Pro

Spongiotic Trachyonychia Treated with Topical Corticosteroids Using the Paper Tape Occlusion Method 27843923 2018 11 13 2296-9195 2 1-2 2016 Sep Skin appendage disorders Skin Appendage Disord Spongiotic Trachyonychia Treated with Topical Corticosteroids Using the Paper Tape Occlusion Method. 49-51 Sakiyama Tomo T Department of Dermatology, Keio University School of Medicine, Tokyo, Japan. Chaya Ayaka A Department of Dermatology, Keio University School of Medicine, Tokyo, Japan. Shimizu Tomoko T (...) Department of Dermatology, Keio University School of Medicine, Tokyo, Japan. Ebihara Tamotsu T Department of Dermatology, Keio University School of Medicine, Tokyo, Japan. Saito Masataka M Department of Dermatology, Keio University School of Medicine, Tokyo, Japan. eng Editorial 2016 05 21 Switzerland Skin Appendage Disord 101670617 2296-9160 Nail matrix Paper tape occlusion method Spongiosis Topical corticosteroids Trachyonychia 2016 02 08 2016 04 22 2016 11 16 6 0 2016 11 16 6 0 2016 11 16 6 1 ppublish

2016 Skin appendage disorders

185. A prospective study of atopic dermatitis managed without topical corticosteroids for a 6-month period Full Text available with Trip Pro

A prospective study of atopic dermatitis managed without topical corticosteroids for a 6-month period Topical corticosteroids (TCS) are regarded as the mainstay treatment for atopic dermatitis (AD). As AD has a tendency to heal naturally, the long-term efficacy of TCS in AD management should be compared with the outcomes seen in patients with AD not using TCS. However, there are few long-term studies that consider patients with AD not using TCS. We designed a prospective multicenter cohort

2016 Clinical, cosmetic and investigational dermatology

186. Topical Corticosteroid Misuse: The Scenario in Patients Attending a Tertiary Care Hospital in New Delhi Full Text available with Trip Pro

Topical Corticosteroid Misuse: The Scenario in Patients Attending a Tertiary Care Hospital in New Delhi Irrational use of Topical Corticosteroid (TC) is quite common in India due to unrestricted availability and use of TC not only by general public but also by physicians and chemists due to quick relief of symptoms in different dermatological conditions.The present study was conducted to evaluate and analyse the prevalence of misuse of TC and the causes behind misuse of TC among patients

2016 Journal of clinical and diagnostic research : JCDR

187. Impact of the Topical Ophthalmic Corticosteroid Loteprednol Etabonate on Intraocular Pressure Full Text available with Trip Pro

Impact of the Topical Ophthalmic Corticosteroid Loteprednol Etabonate on Intraocular Pressure Corticosteroids are a mainstay therapeutic option for the treatment of ocular inflammation. However, safety remains a concern for clinicians, particularly with long-term use. Though highly effective at suppressing inflammatory and allergic responses, topical ophthalmic corticosteroids carry an inherent risk of side effects, including elevated intraocular pressure (IOP), a risk factor (...) for the development of glaucoma. The corticosteroid loteprednol etabonate (LE) contains an ester rather than a ketone at the C-20 position, minimizing the potential for side effects, including IOP elevation. In early pivotal clinical trials of LE ophthalmic suspension for conjunctivitis (allergic, giant papillary), anterior uveitis, and post-operative inflammation, LE had minimal impact on IOP over short-term (<28 days) and long-term (≥28 days) use. Since then, new LE formulations-including a gel, an ointment

2016 Advances in therapy

188. Topical Corticosteroid App

Topical Corticosteroid App Topical Corticosteroid App - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Topical Corticosteroid App The safety and scientific validity of this study is the responsibility (...) the effectiveness of a mobile application to assist in the prescription of topical corticosteroids (TCS), focusing on best fit choices of potency, vehicle and volume. The mobile application will be developed from the results obtained in a systematic literature review and quality assessment of clinical practice guidelines for topical corticosteroid use. The quality of the guidelines will be assessed using the AGREE II tool. After the app user enters in information concerning patients' rash location and desired

2016 Clinical Trials

189. Differences in therapeutic effects of topically applied corticosteroid and tacrolimus on atopic dermatitis-like symptoms in NC/Nga mice. (Abstract)

Differences in therapeutic effects of topically applied corticosteroid and tacrolimus on atopic dermatitis-like symptoms in NC/Nga mice. Topical corticosteroid and calcineurin inhibitor have similar therapeutic benefits in atopic dermatitis (AD), but the differences in therapeutic mechanisms of action of these agents against AD symptoms are not fully understood.This study was performed to examine the different effects of topical betamethasone valerate (BMV), clobetasol propionate (CBP (...) the strongest effect. CBP significantly reduced epidermal thickness compared with Vas and NT. There were no significant differences in the numbers of interleukin-31-immunoreactive cells and mast cells, or in expression of epidermal thymic stromal lymphopoietin among all five groups.The therapeutic potency of TAC against AD-like symptoms, including pruritus, is equal to that of the corticosteroid CBP. Epidermal innervation of sensory nerves itself might not be related to the therapeutic effects of topical

2016 Journal of dermatological science

190. Monitoring of topical corticosteroid phobia in a population of parents with children with atopic dermatitis using the TOPICOP<sup>®</sup> scale: prevalence, risk factors and the impact of therapeutic patient education. (Abstract)

Monitoring of topical corticosteroid phobia in a population of parents with children with atopic dermatitis using the TOPICOP® scale: prevalence, risk factors and the impact of therapeutic patient education. 27608366 2017 03 15 1468-3083 31 3 2017 Mar Journal of the European Academy of Dermatology and Venereology : JEADV J Eur Acad Dermatol Venereol Monitoring of topical corticosteroid phobia in a population of parents with children with atopic dermatitis using the TOPICOP ® scale

2016 Journal of the European Academy of Dermatology and Venereology

191. The effects of oral and topical corticosteroid in rabbit corneas. Full Text available with Trip Pro

The effects of oral and topical corticosteroid in rabbit corneas. To determine the most effective route of administration of corticosteroids in the treatment of ocular surface disease, by characterizing the difference between oral prednisolone and topical dexamethasone administration using an animal model.Pharmacokinetic analyses determined the corticosteroid concentrations in the normal ocular tissues of rabbits after oral or topical administration of corticosteroids using LC-MS/MS. In wound (...) observed between orally and topically administered groups. Pharmacokinetic analyses showed that the distribution of dexamethasone after topical administration was superior to that after oral administration in the cornea. In contrast, both concentrations of corticosteroid applied topically and orally were similar with regards to AUCs (area under the concentration-time curve) in the conjunctiva. Although the healing rate was slower in the topical group, all corneas were almost healed within 96 h

2016 BMC Ophthalmology

192. Topical Corticosteroid Concerns in Dermatological Outpatients: A Cross-Sectional and Interventional Study. (Abstract)

Topical Corticosteroid Concerns in Dermatological Outpatients: A Cross-Sectional and Interventional Study. Topical corticosteroid concerns (TCC) are an important issue in patients with atopic dermatitis, leading to non-adherence with poor disease control and increased health care costs. However, neither the prevalence of TCC in a more comprehensible dermatological population nor the impact of patient information on topical corticosteroids given by clinicians is known. Therefore, we assessed (...) the prevalence, characteristics, and sources of TCC in a dermatological population and the impact of written and oral patient information on TCC.A total of 643 outpatients with various skin diseases answered a 12-item questionnaire while waiting for the doctor's visit. Patients with TCC quantified their concerns on a discrete visual analogue scale before and after patient information, which consisted of written and oral information about topical corticosteroids (TCS) given by dermatologists.The prevalence

2016 Dermatology

193. Use of Corticosteroids before the extraction of Third Molars to reduce post-operative Edema

Use of Corticosteroids before the extraction of Third Molars to reduce post-operative Edema UTCAT2561, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title Use of Corticosteroids Before the Extraction of Third Molars to Reduce Post-Operative Edema Clinical Question Can pre-medication with corticosteroids help in reduction of edema, following extraction of third molars? Clinical Bottom Line Pre-medication (...) with corticosteroids when extracting third molars allows mild-moderate reduction in edema after surgery. Best Evidence (you may view more info by clicking on the PubMed ID link) PubMed ID Author / Year Patient Group Study type (level of evidence) #1) Markiewwicz/2008 10 Clinical Trial Total patients 513 Meta-Analysis, Research support (Non-US Gov) Key results In this study two Treatment groups were used, One receiving Corticosteroids (245 patients) before the extraction of Third molars & the second Control group

2013 UTHSCSA Dental School CAT Library

194. Assessment of adherence to topical corticosteroids in bullous pemphigoid patients. (Abstract)

, INSERM U 657, Rouen University Hospital, Rouen, France. Joly P P Department of Dermatology, INSERM U 905, Institute for Research and Innovation in Biomedicine, Rouen University Hospital, University of Rouen, Rouen, France. eng Letter Multicenter Study 2016 01 20 England Br J Dermatol 0004041 0007-0963 0 Adrenal Cortex Hormones 0 Dermatologic Agents IM Administration, Cutaneous Adrenal Cortex Hormones administration & dosage Adult Aged Aged, 80 and over Dermatologic Agents administration & dosage (...) Assessment of adherence to topical corticosteroids in bullous pemphigoid patients. 26556709 2017 03 06 2017 08 17 1365-2133 174 4 2016 Apr The British journal of dermatology Br. J. Dermatol. Assessment of adherence to topical corticosteroids in patients with bullous pemphigoid. 919-21 10.1111/bjd.14285 Sobocinski V V Department of Dermatology, INSERM U 905, Institute for Research and Innovation in Biomedicine, Rouen University Hospital, University of Rouen, Rouen, France. valerie.sobocinski

2015 British Journal of Dermatology

195. Attitudes of Australian dermatologists to the use and safety of topical corticosteroids in paediatric atopic dermatitis. (Abstract)

Attitudes of Australian dermatologists to the use and safety of topical corticosteroids in paediatric atopic dermatitis. Atopic dermatitis is a common paediatric dermatological condition. Topical corticosteroids (TCS) are central to treatment, but non-adherence leads to poor outcomes and treatment failure. Parents commonly cite TCS phobia as an obstacle to treatment adherence. Dermatologists play a key role as clinician educators around the use, safety and efficacy of TCS.To assess

2015 Australasian Journal of Dermatology

196. A Randomized, Double-Blind, Placebo-Controlled Study of the Effect of a High-Potency Topical Corticosteroid After Sclerotherapy for Reticular and Telangiectatic Veins of the Lower Extremities. (Abstract)

A Randomized, Double-Blind, Placebo-Controlled Study of the Effect of a High-Potency Topical Corticosteroid After Sclerotherapy for Reticular and Telangiectatic Veins of the Lower Extremities. Although typically mild, transient, and expected, most adverse events (AEs) postsclerotherapy are inflammatory in nature.To evaluate the effects of a high-potency topical corticosteroid (TC) applied immediately postsclerotherapy.Subjects undergoing bilateral lower extremity sclerotherapy with polidocanol

2015 Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] Controlled trial quality: uncertain

197. Continuous versus tapering application of the potent topical corticosteroid mometasone furoate in the treatment of vulvar lichen sclerosus: results from a randomized trial. (Abstract)

Continuous versus tapering application of the potent topical corticosteroid mometasone furoate in the treatment of vulvar lichen sclerosus: results from a randomized trial. Topical corticosteroids are the first-line treatment for vulvar lichen sclerosus (VLS). However, evidence on the most appropriate treatment regimen is lacking.To compare the effectiveness and tolerability of tapering vs. continuous application of mometasone furoate (MMF) 0·1% ointment in the treatment of active VLS.Sixty

2015 The British journal of dermatology Controlled trial quality: uncertain

198. Topical Use of Corticosteroid to Prevent Epiretinal Membrane Following Retinal Tear

Topical Use of Corticosteroid to Prevent Epiretinal Membrane Following Retinal Tear Topical Use of Corticosteroid to Prevent Epiretinal Membrane Following Retinal Tear - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before (...) adding more. Topical Use of Corticosteroid to Prevent Epiretinal Membrane Following Retinal Tear The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02412059 Recruitment Status : Completed First Posted : April 8, 2015 Last Update Posted : January 29, 2016 Sponsor: St. Michael's Hospital, Toronto

2015 Clinical Trials

199. A Study to Evaluate the Safety of Lebrikizumab Compared to Topical Corticosteroids in Adult Patients With Atopic Dermatitis

A Study to Evaluate the Safety of Lebrikizumab Compared to Topical Corticosteroids in Adult Patients With Atopic Dermatitis A Study to Evaluate the Safety of Lebrikizumab Compared to Topical Corticosteroids in Adult Patients With Atopic Dermatitis - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached (...) the maximum number of saved studies (100). Please remove one or more studies before adding more. A Study to Evaluate the Safety of Lebrikizumab Compared to Topical Corticosteroids in Adult Patients With Atopic Dermatitis The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02465606 Recruitment Status

2015 Clinical Trials

200. Topical Corticosteroids on the Incidence of Postinflammatory Hyperpigmentation After QsNdYAG Laser

Topical Corticosteroids on the Incidence of Postinflammatory Hyperpigmentation After QsNdYAG Laser Topical Corticosteroids on the Incidence of Postinflammatory Hyperpigmentation After QsNdYAG Laser - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove (...) one or more studies before adding more. Topical Corticosteroids on the Incidence of Postinflammatory Hyperpigmentation After QsNdYAG Laser The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02492373 Recruitment Status : Completed First Posted : July 8, 2015 Last Update Posted : June 1, 2016 Sponsor

2015 Clinical Trials

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