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Topical Corticosteroid

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2. Effects on the Pain of an Infiltration by Acid Hyaluronic Association and Corticoids Versus Only Corticoids in the Rhizarthrosis.

Assessor) Primary Purpose: Treatment Official Title: Effects on the Pain of an Infiltration by Acid Hyaluronic Association and Corticoids Versus Only Corticoids in the Rhizarthrosis. Actual Study Start Date : May 11, 2018 Estimated Primary Completion Date : December 2019 Estimated Study Completion Date : September 2021 Resource links provided by the National Library of Medicine related topics: related topics: available for: Arms and Interventions Go to Arm Intervention/treatment Active Comparator (...) Effects on the Pain of an Infiltration by Acid Hyaluronic Association and Corticoids Versus Only Corticoids in the Rhizarthrosis. Effects on the Pain of an Infiltration by Acid Hyaluronic Association and Corticoids Versus Only Corticoids in the Rhizarthrosis. - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have

2018 Clinical Trials

3. Assessing the response of morphea and limited scleroderma to tranilast: a small prospective study comparing topical corticosteroids to a combination of topical corticosteroids and tranilast Full Text available with Trip Pro

Assessing the response of morphea and limited scleroderma to tranilast: a small prospective study comparing topical corticosteroids to a combination of topical corticosteroids and tranilast Scleroderma is traditionally managed with immunomodulatory agents such as methotrexate, mycophenolate mofetil and corticosteroids. There are anecdotal reports for, and theoretical reasons why, the anti-fibrotic agent tranilast may provide an additional treatment modality.The objective of the current study (...) was to demonstrate if the addition of topical tranilast to an established regime resulted in an improvement in the Localized Scleroderma Assessment Tool (LoSCAT) and modified Rodnan score.A small double-blinded randomized prospective study of 11 pairs of treatment sites in four patients; three with morphea and one with limited scleroderma was performed. All patients continued with their prescribed treatment and applied 0.1% betamethasone valerate in PCCA PracaSil™ (B) to the control site with 0.1% betamethasone

2018 Clinical, cosmetic and investigational dermatology Controlled trial quality: uncertain

4. Topical 5% Minoxidil and Potent Topical Corticosteroid Versus Intralesional Corticosteroid in the Treatment of Alopecia Areata

Topical 5% Minoxidil and Potent Topical Corticosteroid Versus Intralesional Corticosteroid in the Treatment of Alopecia Areata Topical 5% Minoxidil and Potent Topical Corticosteroid Versus Intralesional Corticosteroid in the Treatment of Alopecia Areata - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached (...) the maximum number of saved studies (100). Please remove one or more studies before adding more. Topical 5% Minoxidil and Potent Topical Corticosteroid Versus Intralesional Corticosteroid in the Treatment of Alopecia Areata The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT03535233 Recruitment Status

2018 Clinical Trials

5. Topical Corticosteroids Improve Healing Time in Patients with Aphthous Ulcers

. Applicability The evidence, while of low quality, still supports the application of topical corticosteroids to reduce the healing time of aphthous ulcers. The studies also report a reduction in the occurrence of new ulcers, the size of the ulcers, and the pain experienced by the patient due to the ulcers. A study evaluated in the systematic review shows that topical corticosteroids used intraorally do not cause adrenal suppression, if the patient uses them as instructed. Specialty/Discipline (Oral Medicine (...) Topical Corticosteroids Improve Healing Time in Patients with Aphthous Ulcers UTCAT3273, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title Topical Corticosteroids Improve Healing Time in Patients with Aphthous Ulcers Clinical Question In patients with aphthous ulcers, does treatment with topical corticosteroids, as compared to a placebo, improve healing time of the ulcers? Clinical Bottom Line Patients treated

2017 UTHSCSA Dental School CAT Library

6. Inhaled corticosteroids: A rapid review of the evidence for treatment or prevention of COVID-19

the development of acute respiratory distress syndrome. 2 We performed a rapid review of the literature to assimilate the current scientific data on this topic. EMERGING EVIDENCE We searched Medline, Google Scholar and MedRxive on 6 May 2020 for studies that included terms for inhaled corticosteroids and COVID-19 and other related acute coronavirus respiratory tract infections (search strategy provided below). Google Scholar citations were screened until there were 5 consistent pages of citations (...) Inhaled corticosteroids: A rapid review of the evidence for treatment or prevention of COVID-19 Inhaled corticosteroids: A rapid review of the evidence for treatment or prevention of COVID-19 - CEBM CEBM The Centre for Evidence-Based Medicine develops, promotes and disseminates better evidence for healthcare. Navigate this website Inhaled corticosteroids: A rapid review of the evidence for treatment or prevention of COVID-19 June 22, 2020 Laura C Armitage and Rachel Brettell On behalf

2020 Oxford COVID-19 Evidence Service

7. Successful management of severe post-LASIK Mycobacterium abscessus keratitis with topical amikacin and linezolid, flap ablation, and topical corticosteroids. (Abstract)

Successful management of severe post-LASIK Mycobacterium abscessus keratitis with topical amikacin and linezolid, flap ablation, and topical corticosteroids. This is a case report of post-laser in situ keratomileusis (LASIK) multidrug-resistant Mycobacterium abscessus keratitis managed with combined topical amikacin and linezolid, flap amputation, and corticosteroids. A 34-year-old woman presented with a corneal interface infiltrate 3 weeks after LASIK. Cultures isolated mycobacteria (...) of the inflammation within 1 week. Identification of the mycobacterial pathogen and its susceptibilities is essential given the possibility of multidrug resistance. Topical linezolid can be effective in susceptible species. Corticosteroids can be helpful in cases with severe inflammation.Copyright © 2019. Published by Elsevier Inc.

2019 Journal of cataract and refractive surgery

8. Topical treatments in atopic dermatitis: unexpectedly low use of emollients; use of topical corticosteroid is higher in juvenile patients, higher in male vs females, and shows independent associations with asthma and depression. (Abstract)

Topical treatments in atopic dermatitis: unexpectedly low use of emollients; use of topical corticosteroid is higher in juvenile patients, higher in male vs females, and shows independent associations with asthma and depression. Despite decades of use,the actual amounts of topical corticosteroids (TCS) and emollients used in moderate-to-severe atopic dermatitis (AD) under real-world conditions are unknown. Thus, it remains unclear if inadequate use is widespread.To quantify the use of TCS (...) contributing to AD severity. TCS use does not exceed current guidelines. Accurate quantification of topical treatments provides a widely accessible strategy to measure real-world impact of novel AD treatments. This article is protected by copyright. All rights reserved.This article is protected by copyright. All rights reserved.

2019 British Journal of Dermatology

9. Adrenal Insufficiency in Children With Eosinophilic Esophagitis Treated With Topical Corticosteroids. (Abstract)

Adrenal Insufficiency in Children With Eosinophilic Esophagitis Treated With Topical Corticosteroids. The aim of the study was to identify practices of gastroenterologists screening for adrenal insufficiency (AI) and report prevalence of AI in children with eosinophilic esophagitis (EoE) treated with topical corticosteroids (TCS); compare serum dehydroepiandrosterone sulfate (DHEA-S) levels to morning serum cortisol (MSC) levels as screening tool for AI.A multipart study was conducted. In part (...) 1, a survey about screening practices for AI in children with EoE on TCS was sent to gastroenterologists belonging to a PedsGI listserv and to EoE consortia. In part 2, children with EoE on TCS for ≥6 months were prospectively screened for AI with MSC levels. For subjects with a MSC level of <10 μg/dL, a repeat MSC level and/or confirmatory adrenocorticotropic hormone (ACTH) stimulation testing was offered. AI was defined by peak serum cortisol level <18 μg/dL. In part 3, DHEA-S levels were

2020 Journal of Pediatric Gastroenterology and Nutrition

10. Efficacy and safety of dupilumab with concomitant topical corticosteroids in children 6 to 11 years old with severe atopic dermatitis: a randomized, double-blinded, placebo-controlled phase 3 trial. Full Text available with Trip Pro

Efficacy and safety of dupilumab with concomitant topical corticosteroids in children 6 to 11 years old with severe atopic dermatitis: a randomized, double-blinded, placebo-controlled phase 3 trial. Children with severe atopic dermatitis (AD) have limited treatment options.We report efficacy and safety of dupilumab + topical corticosteroids (TCS) in children aged 6-11 years with severe AD inadequately controlled with topical therapies.In this double-blind, 16-week, phase 3 trial (NCT03345914

2020 Journal of American Academy of Dermatology

11. Clinical outcomes and adherence to topical corticosteroid therapy in women with vulvar lichen sclerosus: A retrospective cohort study. (Abstract)

Clinical outcomes and adherence to topical corticosteroid therapy in women with vulvar lichen sclerosus: A retrospective cohort study. Vulvar lichen sclerosus (VLS) is a progressive dermatitis with significant itching, pain, and sexual dysfunction.To investigate topical steroid use and clinical improvement across multiple specialties.Retrospective cohort study at dermatology, gynecology, and vulvovaginal specialty clinics from 2012-2017. Descriptive statistics and panel logistic regression (...) sexually inactive due to pain; of these, 37% became sexually active after steroid treatment. Steroid adherence was not associated with change in sexual activity.Women with VLS improve more when topical steroids are used exactly as prescribed, though some improvement occurs with imperfect use. Sexual activity documentation is inconsistent, limiting quality-of-life follow-up.Copyright © 2020. Published by Elsevier Inc.

2020 Journal of American Academy of Dermatology

12. Response to Topical Corticosteroid Monotherapy in Mycosis Fungoides. (Abstract)

Response to Topical Corticosteroid Monotherapy in Mycosis Fungoides. Topical corticosteroids alone or in combination with other therapies are widely used to treat Mycosis Fungoides (MF), but data on response rates to their use as monotherapy in MF are limited.Evaluate the efficacy of topical corticosteroid monotherapy in MF; compare gender, age, stage distributions, and histopathological features between responders and non-responders.A retrospective cross-sectional review of MF patients from (...) 2013 to 2019 treated at Thomas Jefferson University was conducted. Patients with biopsy-proven MF, all stages, who received topical corticosteroid monotherapy were included. Response rates were determined by percent change in body surface area (BSA) involvement and modified Severity-Weighted Assessment Tool (mSWAT).Of the 163 MF patients in our database, 23% (37/163) initially received topical steroid monotherapy. 73% (27/37) improved with an average 65% decrease in BSA (67% in mSWAT). 27% (10/37

2020 Journal of American Academy of Dermatology

13. Intranasal Corticosteroids for the Management of Chronic Rhinosinusitis or Nasal Polyposis in Cystic Fibrosis: A Review of Clinical Effectiveness

trial reported that a topical steroid (betamethasone) was effective in reducing the size of nasal polyps for people with cystic fibrosis, without significant improvement in nasal symptoms. There was insufficient evidence to support or refute the use of intranasal corticosteroids for treatment of chronic rhinosinusitis or polyposis for those with cystic fibrosis. Files Rapid Response Summary with Critical Appraisal Published : March 18, 2019 Follow us: © 2019 Canadian Agency for Drugs (...) Intranasal Corticosteroids for the Management of Chronic Rhinosinusitis or Nasal Polyposis in Cystic Fibrosis: A Review of Clinical Effectiveness Intranasal Corticosteroids for the Management of Chronic Rhinosinusitis or Nasal Polyposis in Cystic Fibrosis: A Review of Clinical Effectiveness | CADTH.ca Find the information you need Intranasal Corticosteroids for the Management of Chronic Rhinosinusitis or Nasal Polyposis in Cystic Fibrosis: A Review of Clinical Effectiveness Intranasal

2019 Canadian Agency for Drugs and Technologies in Health - Rapid Review

14. Corticosteroids - topical (skin), nose, and eyes

Corticosteroids - topical (skin), nose, and eyes Corticosteroids - topical (skin), nose, and eyes - NICE CKS Share Corticosteroids - topical (skin), nose, and eyes: Summary Corticosteroids are synthetic analogues of the natural hormones that are produced by the adrenal cortex. Local corticosteroids are predominantly glucocorticoids. They have 4 main effects: Anti-inflammatory. Immunosuppressive. Anti-proliferative (anti-mitotic). Vasoconstrictive. Topical corticosteroids exert these effects (...) of this topic. Background information Background information Definition What are corticosteroids? Corticosteroids are synthetic analogues of the natural hormones that are produced by the adrenal cortex. Like the natural hormones, synthetic corticosteroids can have glucocorticoid and/or mineralocorticoid properties. The glucocorticoid properties are anti-inflammatory, immunosuppressive, anti-proliferative, and vasoconstrictive. The glucocorticoid properties also support a variety of metabolic functions

2018 NICE Clinical Knowledge Summaries

15. Sterol-standardized phytopharmaceutical from ground cherry: Corticoid-like properties on human keratinocytes and fibroblasts and its effects in a randomized double-blind placebo-controlled clinical trial. (Abstract)

Sterol-standardized phytopharmaceutical from ground cherry: Corticoid-like properties on human keratinocytes and fibroblasts and its effects in a randomized double-blind placebo-controlled clinical trial. Topical corticosteroids have been the most commonly prescribed drugs to treat skin inflammation, but their uses can lead to several adverse effects. Nowadays, new pharmacological strategies have been evaluated to improve dermatologic efficacy and reduce adverse effects, including natural (...) response producing corticoid-like effects, but different of hydrocortisone, increased skin repair factors. The effects of phytopharmaceutical cream in the clinical trial promoted a better reduction in skin microcirculation and temperature than hydrocortisone.Taken together, the results indicate that sterol standardized CO2 supercritical preparation of P angulata is a new and innovative phytopharmaceutical with multiple pharmacological effects potentially useful as human skin protective product

2018 Journal of cosmetic dermatology Controlled trial quality: uncertain

16. Intra Articular Injection of Botulinum Toxin Versus Corticoids in Gonarthrosis

of Botulinum Toxin Versus Corticoids in Gonarthrosis by Perfusion MRI:a Superiority, Randomized, Controlled, Double Blind Study Estimated Study Start Date : March 2019 Estimated Primary Completion Date : November 2021 Estimated Study Completion Date : November 2021 Resource links provided by the National Library of Medicine related topics: related topics: available for: Arms and Interventions Go to Arm Intervention/treatment Experimental: Botulinum Toxin Type A 100U one intra-articular injection (...) Intra Articular Injection of Botulinum Toxin Versus Corticoids in Gonarthrosis Intra Articular Injection of Botulinum Toxin Versus Corticoids in Gonarthrosis - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more

2018 Clinical Trials

17. Multimodal Image Study of Retinal Inflammation Markers After Corticoid and Antiangiogenic Treatment in Pacients With Diabetic Macular Edema

: Corticosteroid Study Design Go to Layout table for study information Study Type : Observational Estimated Enrollment : 80 participants Observational Model: Case-Only Time Perspective: Prospective Official Title: Multimodal Image Study of Retinal Inflammation Markers After Corticoid and Antiangiogenic Treatment in Pacients With Diabetic Macular Edema Actual Study Start Date : May 23, 2018 Estimated Primary Completion Date : June 1, 2019 Estimated Study Completion Date : June 1, 2019 Resource links provided (...) Multimodal Image Study of Retinal Inflammation Markers After Corticoid and Antiangiogenic Treatment in Pacients With Diabetic Macular Edema Multimodal Image Study of Retinal Inflammation Markers After Corticoid and Antiangiogenic Treatment in Pacients With Diabetic Macular Edema - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study

2018 Clinical Trials

18. Comparative safety and efficacy of topical mometasone furoate with other topical corticosteroids. Full Text available with Trip Pro

Comparative safety and efficacy of topical mometasone furoate with other topical corticosteroids. Derivatives of hydrocortisone, such as mometasone furoate, a (2') furoate-17 ester with chlorine substitutions at positions 9 and 21, have been designed to improve efficacy and reduce the incidence of adverse effects. An extensive literature search of MEDLINE, Embase and other databases was conducted to review the safety and efficacy of various formulations of topical mometasone furoate. Mometasone (...) biotransformation, and consequently has no significant effect on the hypothalamic-pituitary-adrenal axis. The molecular biotransformation of mometasone furoate in the skin results in a lower affinity with dermal cells than epidermal cells, which contributes to its low atrophogenicity. Sensitisation to mometasone furoate is low. Overall, mometasone furoate is a highly efficacious potent corticosteroid with a low risk of both local and systemic adverse effects.© 2018 Ego Pharmaceuticals Pty Ltd. Australasian

2018 Australasian Journal of Dermatology

19. Systematic review: Best evidence supports topical corticosteroids and routine saline irrigations for medical treatment of chronic rhinosinusitis

Systematic review: Best evidence supports topical corticosteroids and routine saline irrigations for medical treatment of chronic rhinosinusitis Best evidence supports topical corticosteroids and routine saline irrigations for medical treatment of chronic rhinosinusitis | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies (...) , please see our . Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Best evidence supports topical corticosteroids and routine saline irrigations for medical treatment of chronic

2016 Evidence-Based Medicine

20. Corticosteroids for treatment of sore throat Full Text available with Trip Pro

Corticosteroids for treatment of sore throat Corticosteroids for sore throat: a clinical practice guideline | The BMJ Intended for healthcare professionals Username * Password * Edition: Search form Search Search Corticosteroids for... Corticosteroids for sore throat: a clinical practice guideline CC BY NC Open access (Published 20 September 2017) Cite this as: BMJ 2017;358:j4090 Population This recommendation applies to almost all patients with sore throat: People with sore throat Children (...) of oral Dexamethasone (or equivalent dose of alternative corticosteroid) + standard care 10mg Adults: Children: Standard care Analgesics Antibiotics 0.6mg per kg + + / - + Standard care Analgesics Antibiotics + + / - Recommendation Favours steroids Favours no steroids We suggest short course steroids. Discuss with patients in shared decision making. All Applies to Click for details  Strong Benefits outweigh harms for almost everyone. All or nearly all informed patients would likely want this option

2017 BMJ Rapid Recommendations

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