How to Trip Rapid Review

Step 1: Select articles relevant to your search (remember the system is only optimised for single intervention studies)

Step 2: press

Step 3: review the result, and maybe amend the or if you know better! If we're unsure of the overall sentiment of the trial we will display the conclusion under the article title. We then require you to tell us what the correct sentiment is.

1,845 results for

Tongue Carcinoma

by
...
Latest & greatest
Alerts

Export results

Use check boxes to select individual results below

SmartSearch available

Trip's SmartSearch engine has discovered connected searches & results. Click to show

1821. Perivascular-submandibular lymph node metastasis in squamous cell carcinoma of the tongue and floor of mouth. (PubMed)

Perivascular-submandibular lymph node metastasis in squamous cell carcinoma of the tongue and floor of mouth. The goal of this study was to investigate the incidence of occult metastasis in perivascular lymph node and nodal recurrence in these nodal pads in squamous cell carcinoma (SCC) of the tongue and floor of mouth.We performed a prospective analysis of the incidence of an occult metastasis in the perivascular lymph nodes in 55 patients (41 with an oral tongue carcinoma and 14 with a mouth (...) floor carcinoma) who underwent an elective supraomohyoid neck dissection (SOHND) for SCC of the tongue and floor of mouth, from 1997 to 2002. 99 SOHND procedures were performed as follows: 72 in tongue carcinomas and 27 in the mouth floor carcinomas.Clinically occult, but pathologically positive perivascular lymph nodes occurred in four of 72 of the tongue carcinomas and two of 27 of the mouth floor carcinomas. The incidence of the regional recurrence at level I was three of 45.This preliminary

2004 European Journal of Surgical Oncology

1822. Effect of treatment time on outcome of radiotherapy for oral tongue carcinoma. (PubMed)

Effect of treatment time on outcome of radiotherapy for oral tongue carcinoma. To investigate the importance of total treatment time on the outcome of external beam radiotherapy (EBRT) followed by internal brachytherapy for the treatment of oral tongue carcinoma.Ninety-four patients with T1-T2N0 squamous cell carcinoma of the oral tongue were treated using 35-40 Gy EBRT followed by 35-40 Gy interstitial (137)Cs brachytherapy between 1985 and 1995. The interval between the end of EBRT (...) ).The total treatment time was associated with the local control rate in the RT of oral tongue carcinoma. The loss in local control was estimated to be 2.0% per additional day in our series for oral tongue carcinoma.

2003 Biology and Physics

1823. Exclusive low-dose-rate brachytherapy in 279 patients with T2N0 mobile tongue carcinoma. (PubMed)

Exclusive low-dose-rate brachytherapy in 279 patients with T2N0 mobile tongue carcinoma. To evaluate the therapeutic results obtained with (192)Ir low-dose-rate interstitial brachytherapy in T2N0 mobile tongue carcinoma.Between December 1979 and January 1998, 279 patients with T2N0 mobile tongue carcinoma were treated by exclusive low-dose-rate brachytherapy, with or without neck dissection. (192)Ir brachytherapy was performed according to the "Paris system" with a median total dose of 60 Gy (...) , esophagus, or bronchus).Exclusive low-dose-rate brachytherapy is an effective treatment for T2 tongue carcinoma. Regional control and survival are excellent in patients undergoing systematic neck dissection, which is mandatory in our experience because of a high rate of occult lymph node metastases.

2005 Biology and Physics

1824. Tongue carcinoma: tumor volume measurement. (PubMed)

Tongue carcinoma: tumor volume measurement. To validate the semiautomated methods of tongue carcinoma tumor volume measurement by comparing the conventional manual trace method with 2 semiautomated computer methods: seed growing and region deformation.The study population consisted of 16 patients with histology-proven tongue carcinoma. Two head-and-neck radiologists independently measured the tumor volume demonstrated on pretreatment T2-weighted magnetic resonance data sets. The tumor volumes (...) tracing and semiautomated segmentation methods in interobserver reliability at pixel level.The semiautomated methods could achieve satisfactory segmentation results. They could also reduce interoperator variance and obtain a higher interobserver reliability. This study validates the use of semiautomated volume measurement methods for tongue carcinoma.

2004 Biology and Physics

1825. Combined-modality treatment for advanced oral tongue squamous cell carcinoma. (PubMed)

Combined-modality treatment for advanced oral tongue squamous cell carcinoma. The aim of this study was to investigate prognostic factors in advanced-stage oral tongue cancer treated with postoperative adjuvant therapy and to identify indications for adjuvant concomitant chemoradiotherapy (CCRT).We retrospectively reviewed the records of 201 patients with advanced squamous cell carcinoma of the oral tongue managed between January 1995 and November 2002. All had undergone wide excision and neck

2007 Biology and Physics

1826. Tongue and tonsil carcinoma: increasing trends in the U.S. population ages 20-44 years. (PubMed)

Tongue and tonsil carcinoma: increasing trends in the U.S. population ages 20-44 years. An increasing incidence of oral carcinoma among young adults has been reported in the U.S. and Europe. Although the association between human papillomavirus infection and tonsillar carcinoma is now well established, to the authors' knowledge little is known about incidence trends in tonsillar carcinoma among younger adults. The objective of the current study was to explore the trends in both oral cavity (...) and pharyngeal squamous cell carcinoma (SCC) in younger U.S. populations, in particular tongue and tonsillar SCC.Using the 1973-2001 Surveillance, Epidemiology and End Results (SEER) database, we computed age, race, and site-specific trends of oral and pharyngeal (excluding nasopharynx) carcinoma incidence rates. The percent change (PC) and annual percent change (APC) were computed to explore trends in incidence rates over time.There were 2262 SCC of the oral cavity and 1251 SCC of the pharynx reported

Full Text available with Trip Pro

2005 Cancer

1827. Disparity in pathologic and clinical lymph node staging in oral tongue carcinoma. Implication for therapeutic decision making. (PubMed)

Disparity in pathologic and clinical lymph node staging in oral tongue carcinoma. Implication for therapeutic decision making. Regional lymph node metastasis is the most reliable predictor of treatment outcomes for patients with squamous cell carcinoma of the oral tongue (SCCOT). A recent American Joint Committee on Cancer staging update of malignant melanoma has incorporated pathologic lymph node staging. The authors hypothesized that pathologic lymph node staging (pN) would be a more reliable

Full Text available with Trip Pro

2003 Cancer

1828. Management of the node negative early carcinoma tongue (PubMed)

Management of the node negative early carcinoma tongue To determine the role of thickness of the primary lesion in early Squamous Cell Carcinoma (SCC) of the oral tongue for decision-making regarding the management of possible occult cervical node metastases.Tertiary referral centrePatients who were treated by the authors for early (T1, T2) primary lesions in the oral tongue in two malignancy treatment centres of the Armed Forces Medical Services were included in this prospective study. Where (...) % and this compares well with survival rates achieved by other workers.Treatment of neck nodes in early (T1,T2) SCC of the oral tongue can be expectant in cases where tumour thickness is less than 04 mm, but where it is more than 04 mm elective treatment of the neck is recommended.

Full Text available with Trip Pro

2007 Indian Journal of Otolaryngology and Head & Neck Surgery

1829. Expression of C-Myc mRNA in squamous cell carcinoma of the tongue. (PubMed)

Expression of C-Myc mRNA in squamous cell carcinoma of the tongue. The aim of this study was to evaluate clinical significance of C-myc mRNA in patients with tongue cancer.C-myc mRNA expression was studied by RT-PCR in peripheral blood of 25 tongue cancer patients and 24 controls. C-myc protein expression was studied by immunohistochemistry.In tongue cancer patients, pretherapeutic C-myc mRNA expression was significantly higher as compared to controls. In tumor tissues, a trend of low (...) was noted in 72% of the tumors and an inverse correlation was noted between C-myc protein expression and disease stage. In early stage disease, an inverse correlation was noted while in advanced stage disease, a positive correlation was noted.In tongue cancer, downregulation of C-myc mRNA associated with advancement of the disease and worse prognosis.

2007 Journal of Surgical Oncology

1830. Poor prognosis in patients with stage I and II oral tongue squamous cell carcinoma. (PubMed)

Poor prognosis in patients with stage I and II oral tongue squamous cell carcinoma. The objective of this study was to compare survival in patients with squamous cell carcinoma (SCC) of the oral tongue with that in patients with SCC in other oral cavity subsites.Patients with stage I and II (T1-T2N0M0) SCC of the oral cavity diagnosed between 1988 and 2004 were queried by using the Surveillance, Epidemiology, and End Results (SEER) database. The log-rank test was used to compare the overall (...) survival (OS) and cause-specific survival (CSS) of patients who had oral tongue SCC with those of patients who had SCC of other oral cavity subsites. A Cox proportional hazards multivariate analysis was performed to evaluate the influence of covariates on the risk of CSS and OS.Between 1988 and 2004, 6791 patients with stage I and II SCC of the oral cavity were identified. Among them, 40% had oral tongue SCC, and 60% had SCC of other oral cavity subsites. The median patient age was 64 years. The 5-year

Full Text available with Trip Pro

2007 Cancer

1831. The role of novel oncogenes squamous cell carcinoma-related oncogene and phosphatidylinositol 3-kinase p110alpha in squamous cell carcinoma of the oral tongue. (PubMed)

The role of novel oncogenes squamous cell carcinoma-related oncogene and phosphatidylinositol 3-kinase p110alpha in squamous cell carcinoma of the oral tongue. Amplification at chromosome 3q26.3 is a common and crucial event in head and neck squamous cell carcinoma (HNSCC), impacting significantly on tumor progression and clinical outcome. Two novel oncogenes, namely squamous cell carcinoma (SCC)-related oncogene (SCCRO) and PIK3CA (gene encoding phosphatidylinositol-3 kinase catalytic alpha (...) -polypeptide), have been identified as targets of 3q26.3 amplification. This study aimed to delineate the role of SCCRO and PIK3CA in the pathogenesis of oral tongue SCC.The association between gene copy number for SCCRO and PIK3CA measured by fluorescence in situ hybridization and level of mRNA expression quantitated by real-time reverse transcription-PCR was assessed in a panel of human HNSCC cell lines. In addition, gene expression in 49 consecutive primary SCCs of the oral tongue was determined

2003 Clinical Cancer Research

1832. Carcinoma of the tongue: pathological considerations in management of the neck. (PubMed)

Carcinoma of the tongue: pathological considerations in management of the neck. In a series of 76 patients with carcinoma of the tongue the occurrence of metastasis was related to the size and histological features of the primary tumour. 64% of patients with metastasis and 10% of patients with clinically negative neck showed spread beyond the node capsule. Fast tracks (long lymphatic pathways uninterrupted by nodes) seemed to be involved in the spread of metastatic cancer in at least 20

Full Text available with Trip Pro

1996 Journal of the Royal Society of Medicine

1833. Predictive value of malignancy grading systems, DNA content, p53, and angiogenesis for stage I tongue carcinomas. (PubMed)

Predictive value of malignancy grading systems, DNA content, p53, and angiogenesis for stage I tongue carcinomas. To assess the clinical value of malignancy grading systems compared with nuclear DNA content, protein p53, and angiogenesis for predicting recurrence of stage I (UICC, 1987) tongue carcinomas.Histopathological malignancy grading according to Jakobsson and tumour front grading according to Bryne et al were performed on haematoxylin and eosin slides. DNA analysis was performed (...) by image cytometry. Protein p53 and angiogenesis were evaluated by immunohistochemical analysis using antibody CM1 and antibody against factor VIII related antigen, respectively.49 patients with stage I carcinomas of the mobile tongue were included, all treated by local surgical excision alone. Eight patients (16%) suffered from local recurrence during follow up, and 13 (27%) had regional recurrence. Both Jakobsson's malignancy grading system and p53 immunoreactivity proved to be useful predictors

Full Text available with Trip Pro

1999 Journal of Clinical Pathology

1834. [Evolution of the N0 patients with primary carcinoma of the oral tongue treated by interstitial radiumtherapy (author's transl)]. (PubMed)

[Evolution of the N0 patients with primary carcinoma of the oral tongue treated by interstitial radiumtherapy (author's transl)]. In a retrospective and not randomized clinical study we have selected 175 cases of squamous carcinoma of the anterior 2/3 of the tongue treated by interstitial radium therapy on the primary from January 1959 to December 1970. At the end of the treatment 64 patients (36.6%) were operated by radical neck dissection in homolateral lymphatic areas and 111 underwent

1981 La Radiologia medica

1835. MMP-9 activation by tumor trypsin-2 enhances in vivo invasion of human tongue carcinoma cells. (PubMed)

MMP-9 activation by tumor trypsin-2 enhances in vivo invasion of human tongue carcinoma cells. Various human cancer cells express tumor-associated trypsinogen-2 (TAT-2), which can efficiently activate matrix metalloproteinases (MMPs) in vitro. MMP-2 and MMP-9 are particularly associated with the invasive malignant potential of several tumors. To investigate the role of TAT-2 in tumor invasion, we overexpressed TAT-2 in two malignant human squamous cell carcinoma cell lines of tongue and in non

2002 Journal of Dental Research

1836. Hyalinizing clear cell carcinoma of the base of the tongue. (PubMed)

Hyalinizing clear cell carcinoma of the base of the tongue. Clear cell carcinoma of the salivary glands is a rare tumour that represents less than one per cent of all salivary tumours. They are divided into a biphasic, epithelial-myoepithelial carcinoma and a monophasic pattern which may be myoepithelial or ductal in origin. The latter is accompanied by prominent fibrohyaline stroma and has been described recently as hyalinizing clear cell carcinoma (HCCC). Most of the HCCC occur in the oral

2002 Journal of Laryngology & Otology

1837. Long-term survival outcome in transhyoid resection of base of tongue squamous cell carcinoma. (PubMed)

Long-term survival outcome in transhyoid resection of base of tongue squamous cell carcinoma. The transhyoid approach for the resection of squamous cell carcinoma (SCC) of the base of the tongue continues to evolve and remains controversial. We previously reported that the functional outcome of this operation is superior to that of the traditional transmandibular approaches.To report our long-term survival rates for T1, T2, and select T3 SCCs of the base of the tongue using the transhyoid (...) approach.Twenty-eight patients with SCC of the base of the tongue were treated using a transhyoid approach at the University of California, Los Angeles, Medical Center between 1981 and 1998.All 28 patients underwent simultaneous neck dissection, and 27 patients underwent postoperative radiation therapy. The majority of the patients had advanced stage III or IV SCC. Twenty-five of the 28 patients had clear margins in the final pathologic specimen. The overall 3- and 5-year patient survival rates were 88.5

2002 Archives of Otolaryngology Head and Neck Surgery

1838. Clinicopathologic significance of bcl-2 expression in the surgical treatment of oral tongue carcinoma. (PubMed)

Clinicopathologic significance of bcl-2 expression in the surgical treatment of oral tongue carcinoma. There is still controversy on the incidence of positive expression of bcl-2 and its prognostic significance for oral tongue carcinoma patients who are treated by surgery. The present study aims at resolving the controversy on the clinicopathologic significance of bcl-2 in a well selected group of patients who satisfy the recruitment criteria: (1) oral tongue carcinoma, (2) squamous cell (...) carcinoma, (3) primary surgical treatment.Bcl-2 expression was studied by immunohistochemistry on glossectomy specimens of 73 patients. The expression of bcl-2 was correlated with clinicopathologic data.Of the 73 tumours, 11% had positive expression of bcl-2. Bcl-2 expression was not significantly correlated with tumour grade, stage, nodal metastasis and survival.Bcl-2 expression played a minor role in oral tongue carcinoma. It had no significant correlation with tumour grade, stage and nodal metastasis

2002 European Journal of Surgical Oncology

1839. Radiotherapy of stage I and II carcinomas of the mobile tongue and/or floor of the mouth. (PubMed)

Radiotherapy of stage I and II carcinomas of the mobile tongue and/or floor of the mouth. From 1977 to 1990, 94 evaluable patients were treated with iridium-192 implantation in the Centre Claudius Regaud for a Stage I (52 patients) or a Stage II (42 patients) squamous cell carcinoma of the mobile tongue and/or the floor of the mouth. Interstitial brachytherapy was associated with external irradiation in 68 patients (group 1; mean dose, 48 Gy for external irradiation, 26 Gy for brachytherapy (...) ) or was exclusive in 26 patients (group 2; mean dose, 66 Gy). The mean follow-up was 44 months. Eleven acute complications were noted during or immediately after the implant (1 lethal myocardial infarction, 6 hematomas of the tongue which spontaneously resolved, 3 local sepsis). The mean duration of the mucositis was 9 weeks (from 4 to 20 weeks). Ten patients (17%) experienced a late complication (8 in group 1, 2 in group 2): 3 bone necroses requiring hemimandibulectomy (1 post-operative death), 1 tongue

1994 Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

1840. Giant cell arteritis of the tongue associated with squamous cell carcinoma. (PubMed)

Giant cell arteritis of the tongue associated with squamous cell carcinoma. 2794070 1989 11 09 2018 11 13 0021-9746 42 9 1989 Sep Journal of clinical pathology J. Clin. Pathol. Giant cell arteritis of the tongue associated with squamous cell carcinoma. 1001 Misselevitch I I Fradis M M Podoshin L L Barel E E Boss J H JH eng Letter England J Clin Pathol 0376601 0021-9746 AIM IM J Clin Pathol. 1990 Apr;43(4):349 2386572 Carcinoma, Squamous Cell complications Giant Cell Arteritis complications (...) Humans Tongue blood supply Tongue Neoplasms complications 1989 9 1 1989 9 1 0 1 1989 9 1 0 0 ppublish 2794070 PMC501805 J Laryngol Otol. 1983 May;97(5):479-83 6854145 Ann Otol Rhinol Laryngol. 1987 Jul-Aug;96(4):373-9 3619280 Ann Intern Med. 1972 Dec;77(6):845-52 4644163 Ann Intern Med. 1967 Jan;66(1):77-86 6015594

Full Text available with Trip Pro

1989 Journal of Clinical Pathology

To help you find the content you need quickly, you can filter your results via the categories on the right-hand side >>>>