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Tongue Carcinoma

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1801. Evaluation of Ultrasound and PET/CT in the Diagnosis and Monitoring of Giant Cell Arteritis

of glucocorticoid treatment in the subset of LV-GCA patients and the diagnostic accuracy of 18F-FDG PET/CT in cranial artery inflammation in new-onset, treatment naïve c-GCA patients as compared to a control group of patients with a previous diagnosis of malignant melanoma was also evaluated and is registered elsewhere ( Identifier: NCT03285945 and NCT03409913, respectively) Condition or disease Intervention/treatment Giant Cell Arteritis Vasculitis Diagnostic Test: Ultrasound Detailed (...) it is increasingly used in the diagnosis of c-GCA, is readily available and cheap. 18F-FDG PET/CT is an appealing diagnostic tool in LV-GCA suspected patients, since it also evaluates malignancy and infection, differential diagnoses often considered in this disease subset. However, 18F-FDG PET/CT is often not readily available, is expensive and exposes patients to radiation. Moreover, its sensitivity seems to decrease with glucocorticoid (GC) treatment and the window of opportunity in which sensitivity

2018 Clinical Trials

1802. Le lymphangiome circonscrit superficiel de la langue Full Text available with Trip Pro

Le lymphangiome circonscrit superficiel de la langue Superficial circumscribed lymphangiomas are predominantly benign lesions occuring in the cervicofacial area. These malformations of the lymphatic vessels are frequently diagnosed in children. We report the clinical case of lymphangioma of the tongue that occurred in an old man. The differential diagnosis was made primarily with Kaposi's disease, circumscribed angiokeratoma and metastases of a solid tumor. The patient had a biopsy

2018 The Pan African medical journal

1803. Large Vallecular Masses; Differential Diagnosis and Imaging Features Full Text available with Trip Pro

. The imaging features are generally diagnostic for characterization. However, these masses can exhibit indeterminate appearance at imaging. We present a series of five cases which includes two rare presentations: a case of low-grade cribriform adenocarcinoma of the base of tongue and a vallecular lipoma. The other three cases presented for differential diagnosis including benign vallecular cysts and two cases to show that malignant masses arising from neighboring anatomical sites such as tongue base (...) Large Vallecular Masses; Differential Diagnosis and Imaging Features Large vallecular masses are an uncommon disease entity which includes a wide spectrum of rare pathologies. These masses may present as purely vallecular in location or appear as an extension from adjacent anatomical sites like tongue base including lingual tonsils, epiglottis, palatine tonsils, epiglottis, and the remainder of supraglottis. Literature review reveals very rare conditions presenting as vallecular mass lesions

2018 Journal of clinical imaging science

1804. Porphyromonas gingivalis Promotes 4-Nitroquinoline-1-Oxide-Induced Oral Carcinogenesis With an Alteration of Fatty Acid Metabolism Full Text available with Trip Pro

with oral carcinogenesis still remains unclear and its underlying mechanism needs to be addressed. Here, we established a combined experimental system of 4NQO-induced oral carcinoma model and chronic periodontitis model and investigated the effects of P. gingivalis infection on oral carcinogenesis and fatty acid metabolism during oral carcinogenesis. The data showed that in this animal model, P. gingivalis infection induced mice periodontitis, increased the tongue lesion size and multiplicity of each (...) mouse and promoted oral cancer development. P. gingivalis treatment significantly increased the level of free fatty acids and altered the fatty acid profile in tongue tissues and the serum of mice. And P. gingivalis induced the formation of fatty liver of the mice. Besides, immunohistochemical analysis and qRT-PCR showed that the expression of fatty-acid synthase and acetyl-CoA carboxylase 1 were increased in the tongue and liver tissues of 4NQO-treated mice infected with P. gingivalis

2018 Frontiers in microbiology

1805. Appraisal of the Free Ulnar Flap Versatility in Craniofacial Soft-tissue Reconstruction Full Text available with Trip Pro

the presented case series, we hope to emphasize the versatile nature of the free ulnar forearm flap in addressing various craniofacial soft-tissue defects. Following institutional review board approval, a retrospective review of the senior authors' clinical experience performing microvascular free ulnar forearm flap reconstruction of craniofacial soft-tissue defects was performed. A total of 10 patients were identified through our review. Soft-tissue defect locations included lower eyelid (n = 2), tongue (...) and floor of mouth (n = 2), lower lip (n = 2), palatopharyngeal area (n = 1), nose (n = 1), and palate (n = 1). Trauma was the most common defect etiology (n = 5), followed by malignancy (n = 4), and iatrogenic injury in 1 case. All patients demonstrated good aesthetic and functional outcomes related to vision, speech, and oral intake at follow-up when applicable. The free ulnar forearm flap is a versatile reconstructive option that can be used to address a wide spectrum of craniofacial soft-tissue

2018 Plastic and Reconstructive Surgery Global Open

1806. Melatonin protects rats from radiotherapy-induced small intestine toxicity. Full Text available with Trip Pro

induced in the rat small intestine after external irradiation of the tongue, and to explore the potential radio-protective effects of melatonin gel. Male Wistar rats were subjected to irradiation of their tongues with an X-Ray YXLON Y.Tu 320-D03 irradiator, receiving a dose of 7.5 Gy/day for 5 days. For 21 days post-irradiation, rats were treated with 45 mg/day melatonin gel or vehicle, by local application into their mouths. Our results showed that mitochondrial oxidative stress, bioenergetic (...) intestinal mucosa recovery. Our findings suggest that oral treatment with melatonin gel may be a potential preventive therapy for radiotherapy-induced gut toxicity in cancer patients.

2017 PLoS ONE

1807. Sally Crowe: Patient and public involvement—“A smooth sea never made a skilled sailor”

. . . go home, get your NHS number, and ring it through to the surgery straight away, and we will start the referral process. Following several bounces around the system I was diagnosed with a rare, but lucky for me slow growing, cancer in my mouth. I also had an anomaly on my tongue that needed exploring. What did I learn? The experience taught me that I didn’t act on my instincts and wasn’t assertive. Yes folks, the system still makes it hard for patients to be assertive about seemingly “trivial (...) in this article where I reflect on three aspects of my experience with cancer, from a personal and professional perspective. Instinct and being heard I had been bothering about a lump in my mouth for well over a year, and I had mentioned it to others. However, it was my dental hygienist who really listened to me during the summer of 2018. In short it went like this: Me: I’m really worried about this lump. I have had it for ages and no one seems to be taking me seriously. Her: Then we should get it checked out

2019 The BMJ Blog

1808. Perinatal care at the threshold of viability

Oral (directly onto tongue) 0.25 mL (optimal dose uncertain) 78 Paracetamol 75 Oral 15 mg/kg every 6–8 hours Rectal Morphine 75 Oral 80–200 microgram/kg every 4 hours IV injection 50 microgram/kg every 4–6 hours Titrate dose as required SC injection IV infusion 10 microgram/kg/hour Fentanyl 75 Intranasal (via atomiser) 79 1.5 microgram/kg SC injection 1 microgram/kg every 2–4 hours IV injection IV infusion 1 microgram/kg/hour Titrate dose as required Midazolam 79 Intranasal 0.2–0.3 mg/kg Buccal IV

2014 Queensland Health

1809. Status of Cardiovascular Disease and Stroke in Hispanics/Latinos in the United States Full Text available with Trip Pro

Institute’s Los Angeles Latino Eye Study, the National Cancer Institute’s Understanding and Preventing Breast Cancer Disparities in Latinas, and the National Institute on Minority Health and Health Disparities’ San Diego Partnership to Reduce Diabetes and CVD in Latinos) to explore disease risk factors among the different Hispanic subgroups. , Such studies provide an opportunity to examine unique risk factors in collective and disaggregated Hispanic groups. The HCHS/SOL is, to date, the largest cohort (...) Status of Cardiovascular Disease and Stroke in Hispanics/Latinos in the United States Status of Cardiovascular Disease and Stroke in Hispanics/Latinos in the United States | Circulation Search Hello Guest! Login to your account Email Password Keep me logged in Search March 2019 March 2019 March 2019 March 2019 March 2019 February 2019 February 2019 February 2019 February 2019 January 2019 January 2019 January 2019 January 2019 January 2019 This site uses cookies. By continuing to browse

2014 American Heart Association

1810. Modifications in endoscopic practice for pediatric patients

be indicated in pediatric patients for the eval- uation of upper GI tract tumors and pancreatic disorders, characterization of esophageal strictures, and for evalua- tion of enteric duplications. 31-34 Use of a miniprobe that can be passed through conventional endoscopes has increased the potential utility of EUS in infants and chil- dren. 35 EUS may be particularly important in the assess- ment of submucosal lesions, and its indications include cancer staging and pancreatic and biliary disease. Rectal EUS (...) of pedi- atric colonoscopies at the population level is far lower than that of adults. More uncommon, but nevertheless critically important, indications for colonoscopy in children include surveillance for neoplasia in children with long-standing in?ammatory bowel disease 5 and hereditary polyposis syn- dromes 12 as well as for graft-versus-host disease. 13,14 There are few contraindications to performing endo- scopic procedures in children. The size of the patient is rarely a contraindication

2014 American Society for Gastrointestinal Endoscopy

1811. Dysphagia

, cricopharyngeal bar) ? Eosinophilic esophagitis ? Head and neck malignancies and the consequences (e.g., hard fibrotic strictures) of surgical and/or radiotherapeutic interventions on these tumors ? Cervical osteophytes ? Oropharyngeal malignancies and neoplasms (rare) Neuromuscular disturbances: ? Central nervous system diseases such as stroke, Parkinson disease, cranial nerve palsy, or bulbar palsy (e.g., multiple sclerosis, motor neuron disease), amyotrophic lateral sclerosis ? Contractile disturbances (...) dysphagia) Mediastinal diseases —obstruct the esophagus by direct invasion, compression, or through lymph- node enlargement ? Tumors (e.g., lung cancer, lymphoma) ? Infections (e.g., tuberculosis, histoplasmosis) ? Cardiovascular (dilated auricles, vascular compression) Mucosal diseases —narrow the lumen through inflammation, fibrosis, or neoplasia ? Peptic stricture secondary to gastroesophageal reflux disease ? Esophageal rings and webs (sideropenic dysphagia or Plummer –Vinson syndrome) [8

2014 World Gastroenterology Organisation

1812. Quality Improvement Guidelines for Pediatric Gastrostomy and Gastrojejunostomy Tube Placement

). The threshold for these indications is 95%. Wheno 90% of procedures are for these indications, the department will review the process of patient selection. Gastric Feeding Many studies have shown that children with chronic diseases have decreased caloric intake or increased nutritional requirements (9,10). Althoughtemporaryaccesstothegastrointestinaltractcanbeobtained via a natural ori?ce such as with a nasogastric or nasojejunal feeding tube, such tubes are notoriously prone to occlusion and dislodgment (...) in children can lead to cholestatic liver disease and liver failure requiring liver transplantation (9,14,15). For all these reasons, placement of a percutaneousGtubehasbecomeacommonlyperformedprocedure.In adults, the most commonly used arti?cial feeding route is via a gastrostomy with feeds delivered directly into the stomach (8). To receive a G tube, a child must have normal or near-normal gastric and small bowel motility, and gastric anatomy must be adequate (8). At least in the newborn, transpyloric

2014 Society of Interventional Radiology

1813. Communication About Serious Illness Care Goals: A Review and Synthesis of Best Practices

; ; for the American College of Physicians High Value Care Task Force 1 Division of Adult Palliative Care, Department of Psychosocial Oncology and Palliative Care, Dana-Farber Cancer Institute, Boston, Massachusetts 2 Ariadne Labs, Brigham and Women's Hospital & Harvard School of Public Health, Boston, Massachusetts 3 Division of Aging, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts 4 Center for Palliative Care, Harvard Medical School, Boston, Massachusetts 5 Departments of Psychiatry (...) of care. References1.Bernacki, RE, Block, SD. Communication About Serious Illness Care Goals : A Review and Synthesis of Best Practices . JAMA Intern.Med. 2014: 174(12):1-112. Blackhall, LJ, Frank, G et al. Bioethics in a different tongue : The case of truth-telling. J Urban Health.2001:78(1):59-713. Kagawa-Singer M, Blackhall LJ. Negotiating cross-cultural issues at the end of life: \"You got to go where he lives\". JAMA. 2001: 286(23):2993–3001.4. Blackhall, LJ, Murphy, ST et al .Ethnicity

2014 American College of Physicians

1814. Acromegaly Full Text available with Trip Pro

hypertension, diabetes mellitus, cardiovascular disease, osteoarthritis, and sleep apnea. (2|⊕⊕○○) 2.2 We also recommend that such comorbidities be longitudinally monitored and rigorously managed. (Ungraded recommendation) 2.3 We suggest screening for colon neoplasia with colonoscopy at diagnosis. (2|⊕⊕○○) 2.4 We suggest a thyroid ultrasound if there is palpable thyroid nodularity. (2|⊕⊕○○) Evidence Morbidity and mortality from acromegaly are consequences of tumor compression, GH/IGF-1 excess (...) in those found to have a polyp or with persistently elevated IGF-1 and every 10 years in those without a polyp and with normal IGF-1 ( ). Acromegaly is associated with an increase in thyroid volume and nodularity. Disease duration correlates with the number of nodules on palpation ( ). In multicenter studies, 54% of subjects had thyroid nodules (approximately 25% with toxic nodules), 18–20% with diffuse goiter, and 1.2–7.2% with thyroid cancer (> 1-cm papillary thyroid carcinomas) ( – ). Thyroid cancer

2014 The Endocrine Society

1815. Kawasaki disease. The importance of prompt recognition and early referral

2006;cD004175. 20. Zhu Bh, lv hT, Sun l, et al. A meta-analysis on the effect of corticosteroid therapy in Kawasaki disease. eur j Pediatr 2012;171:571–8. 21. Maury cP , Salo e, Pelkonen P . elevated circulat- ing tumor necrosis factor-alpha in patients with Kawasaki disease. j lab clin Med 1989;113:651–4. 22. crystal MA, Syan SK, y eung RS, Dipchand AI, Mccrindle BW. echocardiographic and electrocar- diographic trends in children with acute Kawasaki disease. can j cardiol 2008;24:776–80. 23 (...) Kawasaki disease. The importance of prompt recognition and early referral clinical individuals. 3 Timely treatment reduces coronary artery damage by up to 75%. 4 The aetiology of Kawasaki disease is unknown. It is believed that ubiquitous infection(s) trigger an abnormal host inflammatory response, leading to Kawasaki disease in genetically predisposed children. The diagnostic criteria include fever of at least 5 days duration, together with four of five cardinal clinical criteria, 5 which

2014 Clinical Practice Guidelines Portal

1816. Royal Flying Doctor Service Western Operations Clinical manual part 1.Clinical guidelines

(Paediatric) 5 1.5 The Deteriorating Patient 7 2 CARDIOVASCULAR 1 2.1 Acute Coronary Syndromes 1 2.2 Acute Pulmonary Oedema 6 2.3 Cardiac Arrhythmias 8 3 ENDOCRINE 1 3.1 Diabetic Ketoacidosis 1 3.2 Hypoglycaemia 3 3.3 Hypocalcaemia 5 4 GASTROINTESTINAL 1 4.1 Acute Pancreatitis 1 4.2 Haematemesis and Melaena 3 4.3 Intestinal Obstruction 5 5 GENITOURINARY 1 5.1 Acute / Chronic Renal Failure 1 6 INFECTIOUS DISEASES 1 6.1 Bacterial Meningitis 1 6.2 Meningococcal Infection 3 6.3 Tuberculosis 5 6.4 Meliodosis 6 (...) controlled trial. The Lancet; Jun18-Jun24, 2005; 365, 9477 Fong N. Medical Emergency Response. Operational Directive OD 0040/07. Feb 2007. Department of Health Government of Western Australia.RFDS Western Operations Version 6.0 Clinical Manual Issue Date: January 2013 Part 1 - Clinical Guidelines Section 2 Page 1 Cardiovascular 2 CARDIOVASCULAR 2.1 Acute Coronary Syndromes Theory 1. Acute Coronary Syndromes (ACS) cover a broad spectrum of acute presentations of ischaemic heart disease. This guideline

2014 Clinical Practice Guidelines Portal

1817. Abuse and violence - working with our patients in general practice

apprehended domestic violence order AHPRA Australian Health Practitioner Regulation Agency AMA Australian Medical Association APVO apprehended personal violence order ASCA adults surviving child abuse ASP autism spectrum disorder CBT cognitive behavioural therapy FVO family violence order GBD global burden of disease GLBT gay, lesbian, bisexual, transgender GP general practitioner GRADE Grades of Recommendation, Assessment, Development and Evaluation IMG international medical graduate NATSISS National

2014 Clinical Practice Guidelines Portal

1818. Perinatal care at the threshold of viability

Oral (directly onto tongue) 0.25 mL (optimal dose uncertain) 78 Paracetamol 75 Oral 15 mg/kg every 6–8 hours Rectal Morphine 75 Oral 80–200 microgram/kg every 4 hours IV injection 50 microgram/kg every 4–6 hours Titrate dose as required SC injection IV infusion 10 microgram/kg/hour Fentanyl 75 Intranasal (via atomiser) 79 1.5 microgram/kg SC injection 1 microgram/kg every 2–4 hours IV injection IV infusion 1 microgram/kg/hour Titrate dose as required Midazolam 79 Intranasal 0.2–0.3 mg/kg Buccal IV

2014 Clinical Practice Guidelines Portal

1819. A Randomized Trial of Flattery

. But for most of us, a feedback sandwich is a lot like a tongue sandwich. People really feel: “Oh, feedback sandwich deli man, could I please just have the crisp, airy ciabatta? Hold the tongue.” That’s why I had Mr. Collins from Bio-Medical Engineering hang the height stick in my office 1.75 inches low. What’s the harm, really, if I tell my 5’6” patient that he’s 5’8”? Even if he gets challenged when he goes back to his neighborhood and starts telling people he’s 5’8”? His buddies may well say, “That’s (...) a lie! You’re 5’6”–tops!” But my patient can counter, “Oh yeah? My doctor measured me and he says I’m 5’8”!” I have tremendous admiration for many of my patients: the sisters who trade 12-hour shifts taking care of their 95-year-old mother, intensive care unit survivors with healed-over tracheotomy and feeding tube scars, people who have survived cancer, the loving parents of children with Down syndrome… To such patients I always say the following words: “I have tremendous admiration for you.” You

2014 Clinical Correlations

1820. HIV, viral hepatitis and STIs - a guide for primary care

– A GUIDE FOR PRIMARY HEALTH CARE iii HIV , VIRAL HEPATITIS & STIs A GUIDE FOR PRIMARY CARE 2014 EDITION EXPERT REFERENCE GROUP (EDITORIAL OVERSIGHT) Dr Michael Burke Nepean Sexual Health & HIV Clinic Ms Tracey Cabrie Victorian Infectious Diseases Service, Melbourne Health Associate Professor Ben Cowie Victorian Infectious Diseases Reference Laboratory, Royal Melbourne Hospital, University of Melbourne Professor Greg Dore The Kirby Institute, UNSW Australia Dr Seamus Duffy Tuggerah Medical Centre Dr (...) , Tracey Cabrie, Benjamin Cowie, Gregory Dore, Seamus Duffy, Gail Matthews, Ronald McCoy, Anna McNulty, Simone Strasser, Catriona Ooi, David Youds and Iryna Zablotska COPY EDITOR Mary Sinclair PRINTED BY TTR Print Management INCLUDES INDEX HIV (Viruses) – Handbooks, manuals, etc. HIV infections – Handbooks, manuals, etc. Hepatitis, Viral – Handbooks, manuals, etc. Sexually transmitted diseases – Handbooks, manuals, etc. 616.9792 © Australasian Society for HIV Medicine Inc. 2014 ABN 48 264 545 457 CFN

2014 Clinical Practice Guidelines Portal

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