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Tongue Carcinoma

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1521. Infectious Diseases Society of America Guidelines on the Diagnosis of COVID-19

regularly with a standardized questionnaire for symptoms and known exposures in between visits. Although case reports of disease in patients with malignancies or transplants recipients are accumulating, more information is needed. Research on viral detection, longitudinal follow-up of viral shedding, and clinical outcomes in immunocompromised patients due to multiple underlying conditions are necessary. Definition of the impact of antiviral therapy in this high- risk population is also needed (...) Infectious Diseases Society of America Guidelines on the Diagnosis of COVID-19 Last updated May 6, 2020 and posted online at Please check website for most updated version of these guidelines. Supplementary materials are available here. Version 1.0.1 Infectious Diseases Society of America G8uidelines on the Diagnosis of COVID-19 Kimberly E. Hanson 1 , Angela M. Caliendo 2 , Cesar A. Arias 3 , Janet A. Englund 4 , Mark J. Lee 5 , Mark Loeb 6 , Robin Patel 7

2020 Infectious Diseases Society of America

1522. Nosebleed (Epistaxis) (Full text)

, as the guideline development group (GDG) felt that very young, otherwise healthy children rarely required evaluation for nosebleeds. The group also recognized that literature informing treatment of nosebleeds in infants and toddlers was scant. Additionally, while bleeding from the nose may occur secondary to a variety of systemic diseases and head and neck disorders, this guideline does not apply to patients who have a diagnosed bleeding disorder, tumors of the nose or nasopharynx, vascular malformations (...) , crusting from nasal inflammation, or nasal foreign bodies. Persistent or recurrent nasal bleeding in adolescent males, particularly unilateral nosebleed in the presence of nasal obstruction, could suggest the diagnosis of juvenile nasopharyngeal angiofibroma, an uncommon histologically benign but locally invasive vascular tumor. A recent study of emergency department databases in 4 states showed that children who presented with epistaxis had a mean age of 7.5 years and 57.4% were male. Procedures

2020 American Academy of Otolaryngology - Head and Neck Surgery PubMed abstract

1523. Guidance for Return to Practice for Otolaryngology-Head and Neck Surgery: Part Two

medically Skull base malignancy Salivary cancer • Salivary duct carcinoma • High-grade mucoepidermoid carcinoma • Adenoid cystic carcinomaCarcinoma ex pleomorphic adenoma • Acinic cell carcinomaAdenocarcinoma • Other aggressive, high-grade salivary histology Skin cancer • Melanoma > 1 mm thickness • Merkel cell carcinoma • Advanced-stage, high risk squamous cell carcinoma • Basal cell carcinoma in critical area (i.e., orbit) Time Sensitive – Consider Postpone > 30 days Low-risk DTC lower volume (...) without metastasis Low-grade salivary carcinoma Slower growing BCC 5 Routine – Consider Postpone 30 – 90 days; Reassess after pandemic appears to be resolving Thyroid • Goiter without airway/respiratory compromise • Routine benign thyroid nodules and thyroiditis • Revision DTC with low volume, stable or slow rate of progression Parathyroid • HPT with calcium < 12 mg/dL, without active cardiac, renal, or neuromuscular manifestations Benign salivary lesions and tumors Skin cancer • Melanoma = 1mm

2020 American Academy of Otolaryngology - Head and Neck Surgery

1524. Guideline on the management of patients with giant cell arteritis (Full text)

ischaemia such as visual loss or diplopia and no immediate access to phlebotomy. What evaluations should be performed soon after starting treatment for GCA? 5. Patients treated for GCA should be evaluated for features of the disease relevant to the prognosis, such as clinical and laboratory features of a marked inflammatory response at diagnosis, ischaemic manifestations such as transient visual loss or jaw/tongue claudication and signs or symptoms indicating involvement of the aorta and its proximal (...) claudication [ ]. Visual loss or stroke may occur in GCA, attributed to vascular occlusion; most GCA-associated visual loss occurs prior to glucocorticoid treatment or shortly after treatment initiation, underlining the importance of immediate treatment if the disease is strongly suspected [ , ]. The reported proportion of patients with visual loss in GCA varies depending on the GCA case-finding method and method of ascertainment of visual loss; for example, in a UK study recruiting from a rheumatology

2020 British Society for Rheumatology PubMed abstract

1525. Tocilizumab use in paediatric and adolescent rheumatology Information for health professionals

that this risk is real, although it has also been suggested that the autoimmune disease itself is associated with a small increase in the rate of malignancy (as occurs in adults). It is important that doctors discuss with the families the risk and benefit profile associated with the use of these drugs (PRINTO 2016). Blood monitoring and follow-up schedule: The paediatric and adolescent rheumatology clinical affairs committee acknowledges that the monitoring schedule listed in this document differs from (...) (NSAIDs) and systemic corticosteroids and methotrexate. § Polyarticular course juvenile idiopathic arthritis (pcJIA): by either IV infusion or S/C injection for treating juvenile idiopathic polyarthritis (rheumatoid factor positive or negative, and extended oligoarthritis) in patients two years and older whose disease has responded inadequately to methotrexate (this is defined as 15mg/m2 given subcutaneously once-weekly for at least three months). N.B. Tocilizumab is recommended only if the companies

2020 British Society for Rheumatology

1526. Covid-19: Clinical guide to surgical prioritisation during the coronavirus pandemic

of obstructed renal tract Malignant tumour or Lymph node biopsy Peritoneal Dialysis Catheter Insertion Resection of Posterior Urethral Valves Pyloromyotomy Paediatric Orthopaedic surgery Slipped Upper Femoral Epiphysis MDT Directed Suspected bone or soft tissue malignant tumours Fractures - Displaced articular/ peri- articular/ Forearm/Femoral Exposed metalwork Please note Any delay in treatment, especially of cancers, trauma and life threatening conditions, may lead to adverse outcomes. Other Specialist (...) /otherwise unhealed. Removal of prosthesis - unresponsive to conservative Rx. Burns- reconstruction for severe eyelid closure problems/ microstomia/joint and neck contracture MDT Directed Major soft tissue tumour resection (all sites) MDT Directed Skin cancer resection - All sites. Melanoma/ Poorly di?erentiated cancers/nodal disease/compromise of vital structures, including the eye, nose and ear. Urology MDT directed testicular cancer surgery - non- metastatic. MDT directed penile cancer surgery

2020 NHS England

1527. Snoring

snore. Can be a significant problem for both the patient and his or her bed partner. It may result in serious strain in a relationship and be socially disruptive. Common clinical features in patients who snore are obesity, retrognathia, large tongue, and large tonsils. Most patients will benefit from losing weight, stopping smoking, and avoiding alcohol. Some patients may benefit from using a mandibular advancement splint or from upper airway surgery. Surgical options may produce high initial (...) consumption Down's syndrome gastro-oesophageal reflux active or passive smoking abnormal epiglottis hypo-pharyngeal cysts or tumours rhinitis/nasal obstruction asthma Diagnostic investigations nasal decongestant test Epworth sleepiness score (ESS) snoring scale score TFTs growth hormone level allergy tests sleep study acoustic analysis pharyngeal manometry sleep nasendoscopy head and neck 3-dimensional CT head and neck MRI Treatment algorithm ONGOING Contributors Authors Specialty Registrar

2018 BMJ Best Practice

1528. Oral mucositis

of cancer therapy, with a potential impact on patient prognosis. Lalla RV, Saunders DP, Peterson DE. Chemotherapy or radiation-induced oral mucositis. Dent Clin North Am. 2014;58:341-349. [Figure caption and citation for the preceding image starts]: Mucositis: dorsolateral tongue From the teaching collection of Rajesh V. Lalla, DDS, PhD, CCRP, DABOM; used with permission [Citation ends]. [Figure caption and citation for the preceding (...) with a superficial pseudomembranous membrane) or, rarely, overt necrosis. If severe, may warrant an undesirable chemotherapy dose-reduction and/or a break in radiotherapy. Lesions are often very painful. Treatment is symptomatic and includes oral hygiene and pain control. Preventive treatments include palifermin, low-level laser therapy, and use of ice-chips during chemotherapy infusion therapy. Definition Oral mucositis secondary to cancer therapy is an acute inflammation of the oral mucosa in response

2018 BMJ Best Practice

1529. Assessment of oral ulceration

Necrotising ulcerative gingivitis Syphilis Gonorrhoea Tuberculosis Varicella-zoster virus infection Cytomegalovirus infection Zygomycosis Aspergillosis Histoplasmosis Blastomycosis Paracoccidioidomycosis Infectious mononucleosis (EBV) Squamous cell carcinoma Malignant salivary gland tumours (mucoepidermoid carcinoma and adenoid cystic carcinoma) Non-Hodgkin's lymphoma Kaposi's sarcoma Oral melanoma Contributors Authors Professor Oral Medicine Subject Expert Department of Comprehensive Dentistry UTHSCSA (...) , malnutrition) may present with more severe, widespread, atypical presentations that require a comprehensive assessment. Pathophysiology Most of the mucosa lining the oral cavity (e.g., floor of the mouth, cheeks, ventral tongue) is thin and delicate, rendering it susceptible to trauma. By contrast, the mucosa of the hard palate and gingiva is keratinised and more resistant to injury. The biologically dynamic nature of the oral mucosa makes it vulnerable to the effects of systemic disease. Hodgson TA

2018 BMJ Best Practice

1530. Assessment of aphasia

Alzheimer's disease Traumatic head injury Subdural haematoma Subarachnoid haemorrhage Migraine Herpes encephalitis West Nile encephalitis Bacterial infection/abscess Fungal abscess Prion disease Toxoplasmosis Lyme disease Non-fluent/agrammatic variant primary progressive aphasia (PPA) Semantic variant PPA Logopenic variant PPA Aphasia dysarthria motor neuron disease (amyotrophic lateral sclerosis [ALS]-frontotemporal degeneration) Primary brain tumour Brain metastases Multiple sclerosis Sarcoidosis Acute (...) , slowness, reduced range of movement, or impaired timing and coordination of the muscles of the jaw, lips, tongue, palate, vocal folds, and/or respiratory muscles (the speech articulators). Apraxia of speech is an impairment in the motor planning and programming of the speech articulators that cannot be attributed to dysarthria. These 3 disorders can co-exist, but often occur separately. They can be distinguished by evaluation of language (tests of word and sentence comprehension, naming, repetition

2018 BMJ Best Practice

1531. Assessment of taste disorders

and targeted therapies in patients having solid-tumour cancer or stem cell transplant therapy. Hovan AJ, Williams PM, Stevenson-Moore P, et al. A systematic review of dysgeusia induced by cancer therapies. Support Care Cancer. 2010;18:1081-1087. Approximately 60% of patients receiving systemic chemotherapy will report some dysgeusia, which has been associated with the type of cytotoxic agents and the presence of oral mucositis. Okada N (...) ear infections Upper airway endoscopy Oral surgical procedures Skull base surgery Ramsay Hunt's syndrome Stroke Head trauma Parkinson's disease Alzheimer's dementia Amyotrophic lateral sclerosis Multiple sclerosis Epilepsy Myasthenia gravis Guillain-Barre syndrome Sjogren's syndrome Renal insufficiency Liver failure Diabetes mellitus Hypothyroidism Pontocerebellar angle tumours Paraneoplastic syndrome Iron deficiency Vitamin B12 deficiency Zinc deficiency Contributors Authors Associate Professor

2018 BMJ Best Practice

1532. Assessment of cranial nerve mononeuropathy

) Apical lung tumour (IX, X) Iatrogenic (XI) Cerebrovascular accident (XII) Trauma (I) Neurodegenerative disorders (I) Congenital (I) CNS tumours (I) Optic canal trauma (II) CNS tumours (II) Idiopathic intracranial hypertension (II) Autoimmune disease: (e.g., SLE, Sjogren's, granulomatosis with polyangiitis, Behcet's [II]) Leber's hereditary optic neuropathy (II) Optical toxins or nutritional deficiency (II) Neuromyelitis optica (II) Uncal herniation (III, IV, VI) Migraine (III, IV, VI) Trauma (III, IV (...) ) Neurosarcoidosis (VII) CNS tumours (VII) Trauma (VII) Meningitis (VII) Iatrogenic (VII) Middle ear or mastoid infection (VII) Parotid tumour (VII) HIV associated (VII) Lyme disease (VII) CNS tumours (VIII) CNS tumours (IX, X) Parapharyngeal tumour (IX, X) Meningitis (IX,X) Skull-base osteomyelitis (IX, X) Trauma (IX, X) Parapharyngeal space infection (IX, X) Eagle's syndrome (IX) Cardiovocal syndrome (X) Trauma (XI) CNS tumours (XI) CNS tumours (XII) Progressive bulbar palsy (XII) Chiari I and II malformations

2018 BMJ Best Practice

1533. Achlorhydria

present with signs and/or symptoms of iron, cobalamin (vitamin B12), or calcium deficiency and may predispose to enteric infection with organisms such as Clostridium difficile , Salmonella , and Campylobacter . May interfere with the absorption of certain drugs including thyroxine, ketoconazole, itraconazole, and dipyridamole. The most common cause of hypergastrinaemia. Although the prognosis is excellent, it carries a small increased risk for the development of gastric adenocarcinoma and gastric (...) carcinoid tumour. Definition Achlorhydria indicates the inability to produce gastric acid (i.e., hydrochloric acid [HCl]), even after stimulation with secretagogues (e.g., pentagastrin [gastrin analogue], histamine, betazole [histamine analogue], or a meal). Serum gastrin is a marker for gastric acid output. A decrease in gastric acid interrupts a negative feedback pathway controlling gastrin secretion, and leads to elevated serum gastrin levels (hypergastrinaemia). Schubert ML, Peura DA. Control

2018 BMJ Best Practice

1534. Oral candidiasis

confined to the outline of a dental prosthesis burning oral pain dysphagia or odynophagia rhomboid outline on the dorsal aspect of the tongue continuous or patchy band of erythema, involving the free gingival margin hyposalivation/xerostomia age >60 years female sex poor oral hygiene, especially among denture wearers malabsorption and malnutrition advanced malignancy cancer chemotherapy and radiotherapy HIV infection endocrine disturbance (e.g., diabetes mellitus, hypoparathyroidism, pregnancy (...) , oesophagitis, vulvovaginitis), focal invasion (endophthalmitis, meningitis, endocarditis), and dissemination (candidaemia). History and exam presence of risk factors creamy white or yellowish plaques, fairly adherent to oral mucosa cracks, ulcers, or crusted fissures radiating from angles of the mouth lesions on any part of the oral mucosa atrophic, fiery red, flat lesions on the palate patchy areas of loss of filiform papillae on the dorsum of the tongue spotty red areas on the buccal mucosa lesions

2018 BMJ Best Practice

1535. Kawasaki disease

Kawasaki disease Kawasaki disease - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Kawasaki disease Last reviewed: February 2019 Last updated: March 2018 Summary Acute febrile illness lasting 5 or more days. Typical signs include fever, polymorphic rash, injected eyes, and mucosal erythema with strawberry tongue. Swelling and erythema of the hands and feet occur in the acute stage, followed by desquamation (...) in the second week. Unilateral non-purulent cervical lymphadenopathy is present in about 40% of cases. Coronary aneurysms develop in 20% to 25% of untreated patients. Standard treatment includes intravenous immunoglobulin and/or aspirin. In resistant cases, corticosteroids or a tumour necrosis factor (TNF)-alpha inhibitor may be necessary. Definition Kawasaki disease (KD) is an acute, febrile, self-limiting, systemic vasculitis of unknown origin that almost exclusively affects young children

2018 BMJ Best Practice

1536. Assessment of dysphagia

lateral sclerosis (ALS) Progressive supranuclear palsy Wilson's disease Tardive dyskinesia Idiopathic achalasia Nutcracker oesophagus Caustic agents Pill-induced injury Radiation exposure Oesophageal carcinoma Foreign body Benign oesophageal tumours (leiomyoma, lipoma, polyps) Oesophageal metastases Oesophageal compression Schatzki ring Gastroesophageal muscular ring Oesophageal diverticulum Eosinophilic oesophagitis Oesophageal web Botulism Oral mucositis Cervical osteophytes Contributors Authors (...) candidiasis Stroke Muscle tension dysphagia Diffuse oesophageal spasm Gastro-oesophageal reflux Hiatal hernia Post-operative cervical spine surgery Epiglottitis Retropharyngeal abscess Oropharyngeal carcinoma (squamous cell carcinoma) and metastases Zenker diverticulum Cricopharyngeal bar Thyromegaly (goitre) Cervical lymphadenopathy Oropharyngeal stenosis Parkinson's disease Vocal cord paralysis Multiple sclerosis Myasthenia gravis Sjogren's syndrome Scleroderma Inflammatory myopathies Amyotrophic

2018 BMJ Best Practice

1537. Sepsis: recognition, diagnosis and early management

(see recommendation 1.1.9) – people who have impaired immune function (for example, people with diabetes, people who have had a splenectomy, or people with sickle cell disease) – people taking long-term steroids – people taking immunosuppressant drugs to treat non-malignant disorders such as rheumatoid arthritis • people who have had surgery, or other invasive procedures, in the past 6 weeks • people with any breach of skin integrity (for example, cuts, burns, blisters or skin infections) • people (...) criteria are now becoming available in an area where inconsistent disease coding has hindered the acquisition of good baseline data and therefore of studying management strategies. Studies have been done in hospital settings – particularly in intensive care units. However, with such high mortality the challenge posed has been how to recognise the occurrence of sepsis as early as possible, not just outside of ICU and in the post-operative patient, but in other wards and even in community. The 2017 UK

2018 Best Practice Advocacy Centre New Zealand

1538. Bariatric surgery: an HTA report on the efficacy, safety and cost-effectiveness

morbidity including type 2 diabetes mellitus (T2DM), cardiovascular disease (such as stroke and coronary artery disease), obstructive sleep apnoea, osteoarthritis, obesity related cancers and depression. 3, 6 The risk for these co-morbidities increases with increasing BMI. Especially people with obesity category II (BMI 35 to 30.0 kg/m²). 13 The increased prevalence of comorbidities results in a reduction of life expectancy, and thus a higher early mortality risk. 4, 5 In a recent epidemiologic study (...) arterial disease, nephropathy, neuropathy, retinopathy Hypertension Chronic kidney disease Hyperlipidaemia Peripheral artery disease Other diabetes complications Gastrointestinal Gastro-oesophagal reflux Gallstones Liver fat accumulation and Non- alcoholic steatohepatitis KCE Report 316 Bariatric Surgery 23 Cirrhosis – hepatocellular carcinoma Restricted ventilation Exertional dyspnoe; asthma Obstructive sleep apnoe Obesity hypoventilation syndrome (Pickwick syndrome) Mechanical effects of weight

2019 Belgian Health Care Knowledge Centre

1539. Cost-effectiveness analysis of HPV vaccination of boys in Belgium

cancer, as there is no international consensus on which codes should be considered regarding HPV, we selected ICD codes C01, C05.1-9, and C09-10. These codes show a proportion of HPV positive cases above 10% in an EU multicentre study, are included in the oropharynx definition in the 2018 TNM classification of malignant tumours f and correspond to the outcomes of the Belgian study on HPV oropharyngeal cancers. 6, 25, 26 To estimate the diseases that are attributable to HPV, we extracted (...) HPV and 35% (26; 45) for high-risk HPV types, but included only two European studies. 36 f­ Classification-of-Malignant-Tumours-8th-edition.pdf 18 HPV vaccination of boys KCE Report 308 A small Belgian study estimated the anal prevalence among 149 HIV- negative women without a history of cervical cancer and attending a colposcopy clinic. 34 HPV was found in 56% of the 96 anal samples (compared to 54% of 149 cervical samples). However

2019 Belgian Health Care Knowledge Centre

1540. Management of Cardiovascular Diseases during Pregnancy (Full text)

from the American Heart Association and the American College of Cardiology. Furthermore, we considered related Guidelines of the ESC published in 2012–15 on the topics of congenital heart disease, aortic disease, valvular heart disease, cardiomyopathies and heart failure (HF), coronary artery disease (CAD), hypertension, pericardial diseases, pulmonary hypertension (PH), infective endocarditis (IE), ventricular arrhythmias, and acute coronary syndromes, and on the topics of cancer treatment (...) Management of Cardiovascular Diseases during Pregnancy We use cookies to enhance your experience on our website. By continuing to use our website, you are agreeing to our use of cookies. You can change your cookie settings at any time. 2018 ESC Guidelines for the management of cardiovascular diseases during pregnancy | European Heart Journal | Oxford Academic Search Account Menu Menu Navbar Search Filter Mobile Microsite Search Term Close search filter search input Article Navigation Close

2018 European Society of Cardiology PubMed abstract

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