How to Trip Rapid Review

Step 1: Select articles relevant to your search (remember the system is only optimised for single intervention studies)

Step 2: press

Step 3: review the result, and maybe amend the or if you know better! If we're unsure of the overall sentiment of the trial we will display the conclusion under the article title. We then require you to tell us what the correct sentiment is.

4,191 results for

Tongue Carcinoma

by
...
Latest & greatest
Alerts

Export results

Use check boxes to select individual results below

SmartSearch available

Trip's SmartSearch engine has discovered connected searches & results. Click to show

1981. Burning Mouth Syndrome

Burning Mouth Syndrome Burning Mouth Syndrome Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Burning Mouth Syndrome Burning Mouth (...) in a new browser window. Related Studies (from Trip Database) Ontology: Burning Mouth Syndrome (C0006430) Definition (NCI) A condition characterized by a burning or tingling sensation on the lips, tongue, or entire mouth. Definition (NCI_CTCAE) A disorder characterized by a burning or tingling sensation on the lips, tongue or entire mouth. Definition (MSH) A group of painful oral symptoms associated with a burning or similar sensation. There is usually a significant organic component with a degree

2018 FP Notebook

1982. Giant Cell Arteritis

Giant Cell Arteritis Giant Cell Arteritis Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Giant Cell Arteritis Giant Cell Arteritis (...) leading to occlusive granulomatous vasculitis with transmural infiltrate containing multinucleated GIANT CELLS. The TEMPORAL ARTERY is commonly involved. This disorder appears primarily in people over the age of 50. Symptoms include FEVER; FATIGUE; HEADACHE; visual impairment; pain in the jaw and tongue; and aggravation of pain by cold temperatures. (From Adams et al., Principles of Neurology, 6th ed) Concepts Disease or Syndrome ( T047 ) MSH ICD9 446.5 SnomedCT 155442004 , 195354005 , 195357003

2018 FP Notebook

1983. Generalized Tonic Clonic Seizure

Generalized Tonic Clonic Seizure Generalized Tonic Clonic Seizure Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Generalized Tonic (...) is marked by trunk flexion followed by diffuse extension of the trunk and extremities. The clonic phase features rhythmic flexor contractions of the trunk and limbs, pupillary dilation, elevations of blood pressure and pulse, urinary incontinence, and tongue biting. This is followed by a profound state of depressed consciousness (post-ictal state) which gradually improves over minutes to hours. The disorder may be cryptogenic, familial, or symptomatic (caused by an identified disease process). (From

2018 FP Notebook

1984. Acromegaly

Acromegaly Acromegaly Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Acromegaly Acromegaly Aka: Acromegaly From Related Chapters II (...) dopaminergních agonistů, v těžkých případech somatostatinu. (cit. Velký lékařský slovník online, 2013 http://lekarske.slovniky.cz/ ) Definition (NCI_NCI-GLOSS) A condition in which the pituitary gland makes too much growth hormone after normal growth of the skeleton is finished. This causes the bones of the hands, feet, head, and face to grow larger than normal. Acromegaly can be caused by a pituitary gland tumor. Definition (NCI) A syndrome characterized by enlargement of the hands, feet, ears, nose, lips

2018 FP Notebook

1985. Angioedema

Angioedema Angioedema Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Angioedema Angioedema Aka: Angioedema II. Pathophysiology See (...) of the deep layers of the skin due to transient vascular leakage of serous fluid.(NICHD) Definition (MSH) Swelling involving the deep DERMIS, subcutaneous, or submucosal tissues, representing localized EDEMA. Angioedema often occurs in the face, lips, tongue, and larynx. Concepts Pathologic Function ( T046 ) MSH ICD10 SnomedCT 269433002 , 157756002 , 400075008 , 41291007 , 82966003 English Angioedemas , Angioneurotic Edemas , Edemas, Angioneurotic , Giant Urticarias , Quincke Edema , Quincke's Edema

2018 FP Notebook

1986. Vitamin B6

Vitamin B6 Vitamin B6 Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Vitamin B6 Vitamin B6 Aka: Vitamin B6 , Pyridoxine , Pyridoxal (...) (pyridoxine, pyridoxal, and pyridoxamine) found in cereals, beans, peas, nuts, meat, poultry, fish, eggs, and bananas. It is water-soluble (can dissolve in water). Not enough pyridoxine can cause mouth and tongue sores and nervous disorders. Pyridoxine is being studied in the prevention of hand-foot syndrome (a disorder caused by certain anticancer drugs and marked by pain, swelling, numbness, tingling, or redness of the hands or feet). Definition (MSH) The 4-methanol form of VITAMIN B 6 which

2018 FP Notebook

1987. Oral Complications of Chemotherapy and Head/Neck Radiation (PDQ®): Patient Version

is reviewed regularly and updated as needed, by the PDQ Supportive and Palliative Care Editorial Board. General Information About Oral Complications Key Points for This Section Oral complications are common in cancer patients, especially those with head and neck cancer. are new medical problems that occur during or after a disease, procedure, or treatment and that make harder. The complications may be of the disease or treatment, or they may have other causes. complications affect the mouth. patients have (...) sure that your knows your health history and the cancer treatments you received. Preventing and Treating Oral Complications Before Chemotherapy or Radiation Therapy Begins Key Points for This Section Finding and treating oral problems before cancer treatment begins can prevent oral complications or make them less severe. Problems such as , broken teeth, loose crowns or fillings, and disease can get worse or cause problems during treatment. live in the mouth and may cause an when the is not working

2016 PDQ - NCI's Comprehensive Cancer Database

1988. Oral Complications of Chemotherapy and Head/Neck Radiation (PDQ®): Health Professional Version

of Health (NIH). Overview Aggressive treatment of malignant disease may produce unavoidable toxicities to normal cells. The mucosal lining of the gastrointestinal tract, including the oral mucosa, is a prime target for treatment-related toxicity by virtue of its rapid rate of cell turnover. The oral cavity is highly susceptible to direct and indirect toxic effects of cancer chemotherapy and ionizing radiation.[ ] This risk results from multiple factors, including high rates of cellular turnover (...) , bacterial). Chronic GVHD. Dental/skeletal growth and development alterations (pediatric patients). Xerostomia. Relapse-related oral lesions. Second malignancies. Phase V: Long-term Survival Relapse or second malignancies. Dental/skeletal growth and development alterations. GVHD = graft-versus-host disease. Phase I: Before Chemotherapy Oral complications are related to current systemic and oral health, oral manifestations of underlying disease, and oral complications of recent cancer or other medical

2016 PDQ - NCI's Comprehensive Cancer Database

1989. Langerhans Cell Histiocytosis Treatment (PDQ®): Health Professional Version

remains about whether it is a malignant neoplasm with varying clinical behavior. The same BRAF V600E mutation has been found in other cancers, including malignant melanoma; however, V600E-mutated BRAF is also present in benign nevi, possibly indicating the need for additional mutations to render the cell malignant.[ ] Nevertheless, these findings have raised the possibility of targeted therapy with inhibitors already used in the treatment of melanoma. Several trials of BRAF inhibitors are open (...) mutation occurs is critical in defining the extent of disease in LCH. LCH is now considered a myeloid neoplasm. Clinical implications Clinical implications of the described genomic findings include the following: LCH joins a group of other pediatric entities with activating BRAF mutations, including select nonmalignant conditions (e.g., benign nevi) [ ] and low-grade malignancies (e.g., pilocytic astrocytoma).[ , ] All of these conditions have a generally indolent course, with spontaneous resolution

2016 PDQ - NCI's Comprehensive Cancer Database

1990. Cannabis and Cannabinoids (PDQ®): Health Professional Version

.: Targeting CB2 cannabinoid receptors as a novel therapy to treat malignant lymphoblastic disease. Blood 100 (2): 627-34, 2002. [ ] Casanova ML, Blázquez C, Martínez-Palacio J, et al.: Inhibition of skin tumor growth and angiogenesis in vivo by activation of cannabinoid receptors. J Clin Invest 111 (1): 43-50, 2003. [ ] [ ] Blázquez C, González-Feria L, Alvarez L, et al.: Cannabinoids inhibit the vascular endothelial growth factor pathway in gliomas. Cancer Res 64 (16): 5617-23, 2004. [ ] Guzmán M (...) to be negatively correlated with cancer In cell lines, CBD upregulated ICAM-1, leading to decreased cancer cell invasiveness. In an in vivo model using severe combined immunodeficient mice, subcutaneous tumors were generated by inoculating the animals with cells from human non-small cell lung carcinoma cell lines.[ ] Tumor growth was inhibited by 60% in THC-treated mice compared with vehicle-treated control mice. Tumor specimens revealed that THC had and antiproliferative effects. However, research with murine

2016 PDQ - NCI's Comprehensive Cancer Database

1991. Last Days of Life (PDQ®): Patient Version

. It is most helpful if end-of life planning and decision-making begin soon after the is diagnosed and continue during the course of the disease. Having these decisions in writing can make the patient's wishes clear to both the family and the healthcare team. When a child is , end-of-life discussions with the child's doctor may reduce the time the child spends in the hospital and help the parents feel more prepared. This summary is about end of life in adults with cancer and where noted, children (...) Sudden hemorrhage (heavy bleeding) may occur in patients who have certain cancers or disorders. (heavy bleeding in a short time) is rare but may occur in the last hours or minutes of life. may be damaged by certain cancers or cancer treatments. , for example, can weaken blood vessels in the area that was treated. Tumors can also damage blood vessels. Patients with the following conditions have an increased risk of hemorrhage: , especially . . caused by . . The patient and family should talk

2016 PDQ - NCI's Comprehensive Cancer Database

1992. Cannabis and Cannabinoids (PDQ®): Patient Version

, including the and the (see ). The main psychoactive cannabinoid in Cannabis is delta-9-THC. Another active cannabinoid is cannabidiol (CBD), which may relieve pain, lower , and decrease without causing the "high" of delta-9-THC (see ). Cannabinoids can be taken by mouth, , or sprayed under the tongue (see ). Cannabis and cannabinoids have been studied for relief of pain, and , , and loss of caused by cancer or the of cancer (see ). Two cannabinoid drugs ( and ) are approved by the (FDA (...) into a different psychoactive chemical (11-OH-THC). When Cannabis is smoked and inhaled, cannabinoids quickly enter the bloodstream. The psychoactive chemical (11-OH-THC) is made in smaller amounts than when taken by mouth. A growing number of are studying a made from an of Cannabis that contains specific amounts of cannabinoids. This medicine is sprayed under the tongue. Have any laboratory or animal studies been done using Cannabis or cannabinoids? In , tumor cells are used to test a substance to find out

2016 PDQ - NCI's Comprehensive Cancer Database

1993. Pain (PDQ®): Patient Version

for patients and their families. Manage pain and non-pain . Support patients who need higher of , have a of , or are with emotional and social problems. See the summary on for more information. Radiation therapy is used to relieve pain in patients with skin , , or cancer that has spread to the bone. This is called radiation therapy. It may be given as directly to the tumor or to larger areas of the body. Radiation therapy helps drugs and other treatments work better by shrinking tumors that are causing (...) disease, including cancer. Radiopharmaceuticals may also be used to relieve pain from cancer that has spread to the bone. A single dose of a radioactive agent injected into a may relieve pain when cancer has spread to several areas of bone and/or when there are too many areas to treat with external radiation therapy. Physical medicine and rehabilitation Patients with cancer and pain may lose their strength, freedom of movement, and ability to manage their . or may help these patients. Physical

2016 PDQ - NCI's Comprehensive Cancer Database

1994. Dificlir - fidaxomicin

Microbiology and Infectious Diseases FDA Food and Drug Administration GCP Good Clinical Practice GI Gastrointestinal IC 50 Half maximal inhibitory concentration IDSA Infectious Disease Society of America i.v. Intravenously LC-MS/MS Liquid chromatography tandem mass spectrometry LFT Liver function test LLOQ Lower limit of quantification MIC Minimum inhibitory concentration mITT Modified Intent-to-Treat MedDRA Medical Dictionary for Regulatory Activities MRSA Methicillin-resistant Staphylococcus aureus NAP1 (...) Authorisation to the European Medicines Agency (EMA) for Dificlir, through the centralised procedure under Article 3 (2) (a) of Regulation (EC) No 726/2004. The eligibility to the centralised procedure was agreed upon by the EMA/CHMP on 03 June 2009. The applicant applied for the following indication: “Treatment of Clostridium difficile infections (CDI) also known as C. difficile-associated disease (CDAD) and prevention of recurrences (see Section 5.1).” The legal basis for this application refers

2011 European Medicines Agency - EPARs

1995. Halaven - eribulin

recognition system LLDPE Linear low density polyethylene LRBC Locally recurrent breast cancer MBC Metastatic breast cancer MedDRA Medical Dictionary for Regulatory Activities MS Mass spectrometry MTD Maximum tolerated dose NA Not applicable NCI National Cancer Institute NOAEL No-Observed-Adverse-Effect Level NSCLC Non-small cell lung cancer ORR Objective response rate OS Overall survival CHMP assessment report doc ref EMA/CHMP/5019/2011 Page 4/70 PD Progressive disease PFS Progression-Free Survival P-gp (...) -authorisation on 19 January 2011. CHMP assessment report doc ref EMA/CHMP/5019/2011 Page 7/70 2. Scientific discussion 2.1. Introduction Breast cancer is the most frequent cancer in women worldwide with an estimated 1.38 million new cases in 2008, constituting 23% of all cancers in women. Approximately 1 in 8 women will develop breast cancer in their lifetime. While a small proportion of patients have advanced disease at diagnosis, around one third will eventually have metastatic disease, for which

2011 European Medicines Agency - EPARs

1996. Fentanyl sublingual spray

disease, and tongue piercings • ECG and laboratory investigations to include hematology, chemistry, urine pregnancy test for females of childbearing potential, and urinalysis (no more than 28 days before the open-label dose-titration period) • Report number of BTCP episodes and assess persistent cancer related pain intensity in a 24-hour period prior to Screening Visit using the Pain Intensity (PI) 5-point categorical scale (none=0, mild=1, moderate=2, severe=3 and excruciating=4); controlled (...) . Transient ischemic attacks, neural vascular disease, stroke, or cerebral aneurysms within the past two years 7. Diagnosis of sleep apnea 8. Painful erythema, edema or ulcers under the tongue 9. Serum creatinine, ALT or AST more than three times the upper limit of normal Amendment 3 (06 December 2007): • Use of methadone within 14 days of Screening Visit was to have been no longer an exclusion criterion. • “Diagnosis of sleep apnea” was to have been changed to “clinically uncontrolled sleep apnea

2011 FDA - Drug Approval Package

1998. The key to this patient? Horseshoes.

The key to this patient? Horseshoes. The key to this patient? Horseshoes. The key to this patient? Horseshoes. | | October 12, 2018 4 Shares “Those who suffer illness learn by hearing themselves tell their stories, absorbing others’ reactions, and experiencing their stories being shared.” – Arthur Frank We stand together at the clinic room door, preparing to enter. “Tongue cancer. This is a 78-year-old man with an oral cavity mass and some memory loss. He had an ulcer on the side of his tongue (...) hands again and they are on their way. “What did you learn?” I ask Tanya. “That was really interesting,” she says. “Now I know more about managing tongue cancer.” “But,” I ask, “do you know more about horseshoes?” She laughs. “I sure do,” she says. “That was amazing. He really seemed to enjoy talking about his story.” And so he did. By drawing out his narrative and putting his cancer in the larger context of his life, his passion had driven the conversation. It took only a couple of questions

2018 KevinMD blog

1999. Newly Diagnosed with Hepatitis B? How Did I Get this? Learning the HBV Basics, Transmission – Part I

in life that they are hepatitis B positive, even though they have likely had HBV since birth or early-childhood. . Greater than 90% of babies and up to 50% of young children infected with HBV will remain chronically infected, and most will have no symptoms. Often it remains undetected until it is caught in routine blood work, blood donation, or later in life after there is liver inflammation or disease progression. In Asia, vertical transmission from mother to child is particularly common; whereas (...) is a vaccine preventable disease, but not all moms living with the virus have access to the birth dose for their baby or able to complete the vaccine series, or they have a high viral load resulting in failure of HBV birth prophylaxis. The good news is that today we can . If you do, or have participated in high-risk activities at some point in your life, you are also at greater risk. This is not a time to judge or be judged. Time to move forward. Unless your infection is acute and you can definitively

2018 hepbblog

2000. A pharma shill working on behalf of an industry-funded group shows how easy it is to publish propaganda as a legitimate op-ed

with a skeptical bent and a rather aggressive proclivity towards defending science-based medicine, I generally like STAT News. Sure, it's occasionally screwed up royally (e.g., its on a patient of cancer quack Stanislaw Burzynski named Neil Fachon), but in general it's usually a good source of medical news and analysis. No publication is perfect, of course, but STATNews is generally better than average, and I appreciate that. That's why I was disappointed to see how thoroughly a pharma-backed astroturf group (...) patterns. That can lead to people not getting the best medications for their illnesses. By one calculation, the average American patient fails to receive the recommended drug in nearly one 1 of every 3 doctor visits. Drug company representatives can provide doctors with vital nuggets of information on the latest treatments while preserving their freedom to treat patients as they see fit. He even used an anecdote about how a drug rep told him about a new drug to treat Parkinson's disease psychosis

2017 Respectful Insolence

To help you find the content you need quickly, you can filter your results via the categories on the right-hand side >>>>