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Tongue Pain

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1. The association between electronic-cigarette use and self-reported oral symptoms including cracked or broken teeth and tongue and/or inside-cheek pain among adolescents: A cross-sectional study. Full Text available with Trip Pro

The association between electronic-cigarette use and self-reported oral symptoms including cracked or broken teeth and tongue and/or inside-cheek pain among adolescents: A cross-sectional study. Little is known about oral health related to electronic-cigarette (EC) use, even though EC use is increasing rapidly. The aim of this study is to assess the relationship between EC use and oral health, including 'gingival pain and/or bleeding', 'tongue and/or inside-cheek pain', and 'cracked or broken (...) teeth' among adolescents.A total of 65,528 students in 2016 were included in this cross-sectional study.For EC use, 0.5% (n = 297) students were daily users, 1.9% (n = 1259) were '1 to 29 days past month users', and 5.9% (n = 3848) were former users. Overall, 18.5% students reported they had experienced 'gingival pain and/or bleeding', 11.0% reported 'tongue and/or inside-cheek pain', and 11.4% reported a 'cracked or broken tooth' within the past 12 months. When comparing 'daily EC users', '1 to 29

2017 PLoS ONE

2. Fissured, hairy, and geographic tongue

on the dorsal midline tongue (hairy tongue) well-demarcated areas of erythema on the dorsal tongue (geographic tongue) atrophic red central zone within patches (geographic tongue) lesions that seem to migrate (geographic tongue) halitosis (hairy tongue and fissured tongue) bad taste in mouth (hairy tongue) discolouration (hairy tongue and fissured tongue) burning sensation (geographic tongue) oral mucosal pain (hairy tongue) tobacco use (hairy tongue) coffee/tea consumption (hairy tongue) Melkersson (...) Fissured, hairy, and geographic tongue Fissured, hairy, and geographic tongue - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Fissured, hairy, and geographic tongue Last reviewed: February 2019 Last updated: November 2017 Summary Fissured tongue is a normal variant of tongue appearance and is not considered a pathological entity. It generally presents in healthy people; however, it is also seen in association

2017 BMJ Best Practice

3. Frenotomy for tongue-tie in newborn infants. Full Text available with Trip Pro

Frenotomy for tongue-tie in newborn infants. Tongue-tie, or ankyloglossia, is a condition whereby the lingual frenulum attaches near the tip of the tongue and may be short, tight and thick. Tongue-tie is present in 4% to 11% of newborns. Tongue-tie has been cited as a cause of poor breastfeeding and maternal nipple pain. Frenotomy, which is commonly performed, may correct the restriction to tongue movement and allow more effective breastfeeding with less maternal nipple pain.To determine (...) infant feeding, maternal nipple pain, duration of breastfeeding, cessation of breastfeeding, infant pain, excessive bleeding, infection at the site of frenotomy, ulceration at the site of frenotomy, damage to the tongue and/or submandibular ducts and recurrence of tongue-tie. We used the GRADE approach to assess the quality of evidence.Five randomised trials met our inclusion criteria (n = 302). Three studies objectively measured infant breastfeeding using standardised assessment tools. Pooled

2017 Cochrane

4. Relationship between Tongue Temperature Estimated by Infrared Thermography, Tongue Color, and Cold-Heat Pathological Patterns: A Retrospective Chart Review Study. Full Text available with Trip Pro

> center and root > tip). Tongue temperature was positively correlated with luminance (r: 0.236-0.246), indicating that a higher temperature was associated with a brighter color. The factor analysis extracted two factors (cold sensitivity-pain and discharge-complexion factors) from the CP items and three factors (heat sensation-pain, discharge-breath, and cold preference-thirst factors) from the HP items. Tongue temperature was negatively correlated with the discharge-complexion factor of CP (...) Relationship between Tongue Temperature Estimated by Infrared Thermography, Tongue Color, and Cold-Heat Pathological Patterns: A Retrospective Chart Review Study. Tongue diagnosis is a technique used to determine cold-heat pathologic patterns (CHPPs). Herein, we reviewed electronic medical records of tongue temperature measured using infrared thermography (IRT), tongue color (luminance, green/red, and blue/yellow balance), cold-heat pattern questionnaires (CHPQ), and body temperature for 134

2018 Evidence-based Complementary and Alternative Medicine (eCAM)

5. Tongue Pain

Tongue Pain Tongue Pain Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Tongue Pain Tongue Pain Aka: Tongue Pain , Tongue Burning (...) , Glossitis II. Causes: Burning Tongue with no lesions abuse Early non-specific Glossitis Menopausal Glossitis Heavy metal III. Causes: Tongue Pain from deep lesion of submaxillary or Foreign body of lingual muscles Trichinosis Periostitis of Lingual muscle neoplasm IV. Causes: Tongue Pain from localized superficial lesions biting Lingual frenulum Dental ulcer Foreign body (e.g. fish bone) Ranula Epithelioma or carcinoma ulcer ( ) Candida albicans ( ) Vesiculoerosive lesions V. Causes: Tongue Pain from

2018 FP Notebook

6. The life and work of Antonio Maria Valsalva (1666–1723) – Popping ears and tingling tongues Full Text available with Trip Pro

The life and work of Antonio Maria Valsalva (1666–1723) – Popping ears and tingling tongues The Valsalva manoeuvre is the increase in intra-thoracic pressure achieved by attempted expiration against a closed upper airway. The contraction of abdominal and other accessory muscles of respiration attempt to decrease the intra-thoracic volume, whilst the airway is closed either by the forceful apposition of the vocal cords or else by firmly closing the lips and sealing off the nose (e.g (...) . by pinching it). Valsalva described this manoeuver as a way of checking the patency of the Eustachian tube. However, it has found other uses, including as a way to terminate episodes of supraventricular tachycardia and stopping ear popping-pain on high altitude flights. But who was Valsalva?

2017 Journal of the Intensive Care Society

7. A case report of a tongue ulcer presented as the first sign of occult tuberculosis. Full Text available with Trip Pro

requiring the early diagnosis and prompt treatment.A 57-year-old male patient presented with chief complaint of painful ulcer on tip of his tongue. He reported that the ulcer developed without any remarkable event such as mechanical trauma, vesicle formation or systemic illness. His past medical history revealed the TB over 40 years ago, which had reportedly healed after pharmacological treatments. As the ulceration persisted after topical steroid application and careful education about avoiding (...) A case report of a tongue ulcer presented as the first sign of occult tuberculosis. Tuberculosis (TB) is a serious infectious disease with considerable fatality, typically affecting the pulmonary system and, rarely, other body organs including the oral cavity. Due to the rarity of oral TB, it is frequently overlooked in differential diagnosis of oral lesions. Despite a declining trend in TB incidence in recent years, it is still a major public health problem with high contagiousness, thereby

2019 BMC Oral Health

8. Endothelin Signaling Contributes to Modulation of Nociception in Early-stage Tongue Cancer in Rats. (Abstract)

Endothelin Signaling Contributes to Modulation of Nociception in Early-stage Tongue Cancer in Rats. Patients with early stage tongue cancer do not frequently complain of tongue pain. Endothelin-1 signaling is upregulated in the cancerous tongue at the early stage. We tested the hypothesis that endothelin-1 signaling contributes to the modulation of tongue nociception.Squamous cell carcinoma cells were inoculated into the tongue under general anesthesia. Lingual mechanical sensitivity under (...) light anesthesia using forceps from days 1 to 21 (n = 8) and the amounts of endothelin-1 and β-endorphin in the tongue on days 6, 14, and 21 (n = 5 to 7) were examined after the inoculation. The effect of endothelin-A or µ-opioid receptor antagonism on the mechanical sensitivity was examined (n = 5 to 7).Lingual mechanical sensitivity did not change at the early stage (days 5 to 6) but increased at the late stage (days 13 to 14). The amount of endothelin-1 increased (25.4 ± 4.8 pg/ml vs. 15.0 ± 5.2

2018 Anesthesiology

9. Modified triceps fascial tongue approach for primary total elbow arthroplasty. Full Text available with Trip Pro

months) of follow-up. Every TEA was performed using the modified triceps fascial tongue approach, with the Coonrad-Morrey prosthesis. Patient demographics, range of motion, pain visual analog scale, and triceps strength (Medical Research Council [MRC] scale) were compared before and after the operation. The Mayo Elbow Performance Score was evaluated at the latest follow-up.Triceps strength was normal (MRC grade V) in 10 elbows (48%) and good (MRC grade IV) in 11 (52%). Triceps strength after (...) Modified triceps fascial tongue approach for primary total elbow arthroplasty. Triceps weakness is a common complication of total elbow arthroplasty (TEA). Many posterior approaches for TEA have been introduced to maintain triceps function. The present study evaluated the clinical outcomes and extensor strengths of primary TEA with modified triceps fascial tongue approach.Twenty-one primary TEAs performed in 20 patients by a single surgeon were reviewed with a mean of 64.2 months (range, 24-127

2018 Journal of Shoulder and Elbow Surgery

10. Motor Imagery Exercise and Tongue Strength

or past problem with pain disorders involving the jaw muscles or joint of the mandible (e.g., TMJ (temporomandibular) disorder or myofacial pain disorder) - these are contraindicated for tongue strengthening exercises Presence of oral piercings/oral apparatus that may interfere with tongue exercises Medical conditions that would affect oral motor performance (e.g., history of acute or degenerative neurological condition, head/neck cancer), as determined by investigator History of a diagnosed dementia (...) Motor Imagery Exercise and Tongue Strength Motor Imagery Exercise and Tongue Strength - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Motor Imagery Exercise and Tongue Strength The safety and scientific

2018 Clinical Trials

11. Involvement of Microglial P2Y12 Signaling in Tongue Cancer Pain. (Abstract)

Involvement of Microglial P2Y12 Signaling in Tongue Cancer Pain. To elucidate if microglial P2Y12 receptor (P2Y12R) mechanisms are involved in the trigeminal spinal subnucleus caudalis (Vc; also known as the medullary dorsal horn) in intraoral cancer pain, we developed a rat model of tongue cancer pain. Squamous cell carcinoma (SCC) cells were inoculated into the tongue of rats; sham control rats received the vehicle instead. Nociceptive behavior was measured as the head-withdrawal reflex (...) threshold (HWRT) to mechanical or heat stimulation applied to the tongue under light anesthesia. On day 14 after the SCC inoculation, activated microglia and P2Y12R expression were examined immunohistochemically in the Vc. The HWRT was also studied in SCC-inoculated rats with successive intra-cisterna magna (i.c.m.) administration of specific P2Y12R antagonist (MRS2395) or intraperitoneal administration of minocycline, a microglial activation inhibitor. Tongue cancer was histologically verified in SCC

2016 Journal of Dental Research

12. Four synchronous cancers in a patient with tongue pain as the only symptom Full Text available with Trip Pro

Four synchronous cancers in a patient with tongue pain as the only symptom Synchronous carcinomas may be present in up to 6% of patients with head and neck squamous cell carcinoma (HNSCC) and thus may represent a significant factor in the disease burden. This case report illustrates the importance of a thorough examination of these patients. This patient presented with three synchronous squamous cell carcinomas, two in the tongue and one in the aryepiglottic fold. Positron emission tomography

2016 BMJ case reports

13. ERK-GluR1 phosphorylation in trigeminal spinal subnucleus caudalis neurons is involved in pain associated with dry tongue Full Text available with Trip Pro

ERK-GluR1 phosphorylation in trigeminal spinal subnucleus caudalis neurons is involved in pain associated with dry tongue Dry mouth is known to cause severe pain in the intraoral structures, and many dry mouth patients have been suffering from intraoral pain. In development of an appropriate treatment, it is crucial to study the mechanisms underlying intraoral pain associated with dry mouth, yet the detailed mechanisms are not fully understood. To evaluate the mechanisms underlying pain related (...) to dry mouth, the dry-tongue rat model was developed. Hence, the mechanical or heat nocifensive reflex, the phosphorylated extracellular signal-regulated kinase and phosphorylated GluR1-IR immunohistochemistries, and the single neuronal activity were examined in the trigeminal spinal subnucleus caudalis of dry-tongue rats.The head-withdrawal reflex threshold to mechanical, but not heat, stimulation of the tongue was significantly decreased on day 7 after tongue drying. The mechanical, but not heat

2016 Molecular pain

14. Involvement of peripheral artemin signaling in tongue pain: possible mechanism in burning mouth syndrome. (Abstract)

Involvement of peripheral artemin signaling in tongue pain: possible mechanism in burning mouth syndrome. Burning mouth syndrome is characterized by altered sensory qualities, namely tongue pain hypersensitivity. We found that the mRNA expression of Artemin (Artn) in the tongue mucosa of patients with burning mouth syndrome was significantly higher than that of control subjects, and we developed a mouse model of burning mouth syndrome by application of 2,4,6-trinitrobenzene sulfonic acid (TNBS (...) ) diluted with 50% ethanol to the dorsum of the tongue. TNBS treatment to the tongue induced persistent, week-long, noninflammatory tongue pain and a significant increase in Artn expression in the tongue mucosa and marked tongue heat hyperalgesia. Following TNBS treatment, the successive administration of the transient receptor potential vanilloid 1 (TRPV1) antagonist SB366791 or neutralizing anti-Artn antibody completely inhibited the heat hyperalgesia. The number of glial cell line-derived

2015 Pain

15. Evaluation of neuropathic pain occurring after high-dose-rate interstitial brachytherapy of oral tongue Full Text available with Trip Pro

Evaluation of neuropathic pain occurring after high-dose-rate interstitial brachytherapy of oral tongue To recognize neuropathic pain as a complication of high-dose-rate (HDR) interstitial brachytherapy of oral tongue and to evaluate the possible causes of neuropathy.Twenty one patients who underwent interstitial brachytherapy for early cancer of oral tongue were evaluated. The patients either underwent primary brachytherapy (42-48 Gy at 3-4 Gy/fraction) or a boost (18-24 Gy at 3 Gy/fraction (...) likely to develop neuropathy. Among the patients receiving boost treatment, the equivalent dose at 2 Gy/fraction (EQD2) to 2 cc of SLS was higher (39.25 Gy) in the patients who developed pain compared to those without pain (10.29 Gy).This is the first report to recognize neuropathic pain as a complication of HDR brachytherapy of oral tongue. Patients undergoing primary brachytherapy were more likely to develop pain. Among other factors like dose to SLS, number of catheters, size of the primary tumor

2015 Journal of contemporary brachytherapy

16. Neck-Tongue syndrome: A systematic review. (Abstract)

Neck-Tongue syndrome: A systematic review. Objective Neck-Tongue syndrome (NTS) is characterized by brief attacks of neck or occipital pain, or both, brought out by abrupt head turning and accompanied by ipsilateral tongue symptoms. As the disorder is rare, we undertook a systematic review of the literature to identify all reported cases in order to phenotype clinically the disorder and subsequently inform clinical diagnostic criteria. Methods Two electronic databases were searched using (...) %) experienced neck pain, seven (18%) occipital pain, and 11 (29%) both. Pain was most often sharp or stabbing and severe, lasting several seconds to several minutes. Eleven experienced numbness and/or tingling in the neck/occiput following the pain. Thirty-six had an accompanying tongue sensory disturbance and three a motor/posture disturbance; five had both. Thirteen had other headaches, and four a family history of Neck-Tongue syndrome. Conclusions Neck-Tongue syndrome typically has pediatric

2017 Cephalalgia : an international journal of headache

17. Effect of frenotomy on breastfeeding variables in infants with ankyloglossia (tongue-tie): a prospective before and after cohort study. Full Text available with Trip Pro

Effect of frenotomy on breastfeeding variables in infants with ankyloglossia (tongue-tie): a prospective before and after cohort study. Controversy exists regarding ankyloglossia (tongue-tie) and its clinical impact on breastfeeding, including the benefits, or otherwise, of tongue-tie release (frenotomy). As exclusive breastfeeding rates in Ireland are already considerably low (46% on discharge home from the maternity unit following birth in 2014), it is imperative to protect and support (...) questionnaire. The most common reason for seeking a frenotomy was difficulty with latch (38%). Private lactation consultants were the main person recommending a frenotomy (31%). Rates of exclusive breastfeeding remained similar pre- and post-frenotomy (58% versus 58%), although rates of formula feeding increased two-fold at follow-up. Infants' ability to extend their tongues to the lower lip after frenotomy was significantly increased (p < 0.0001). Almost all participants (91%) reported an overall

2017 BMC Pregnancy and Childbirth

18. A case report of tongue metastasis from lung squamous cell carcinoma and literature review. Full Text available with Trip Pro

systemic chemotherapy, but continued to have pain at the base of his tongue and died 7 months later.From sequencing data, mutations in KRAS proto-oncogene, GTPase (KRAS), phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha (PIK3CA), and tumor protein p53 (TP53) were found in the tumor biopsy of the patient. All of these were indicators of poor prognosis. (...) A case report of tongue metastasis from lung squamous cell carcinoma and literature review. Tongue metastasis from lung cancer is extremely rare, and the prognosis of these patients is rather poor.A 56-year-old man was found a 4-cm cavity lesion in the left upper lobe, which was initially misdiagnosed as tuberculosis.A case of lung squamous cell carcinoma that metastasized to the base of a patient's tongue.We send the biopsy of the lung and the tongue lesions for gene sequencing.He received

2017 Medicine

19. Cardiac metastasis of tongue squamous cell carcinoma complicated by pulmonary embolism: A case report. Full Text available with Trip Pro

Cardiac metastasis of tongue squamous cell carcinoma complicated by pulmonary embolism: A case report. Cardiac metastasis is known as a rare complication of head and neck malignancy.We present a 58-year-old woman patient with a history of tongue carcinoma who was admitted in emergency department for sudden chest pain. Imaging work-up by computed tomography (CT) and positron emission tomography-computed tomography (PET-CT) diagnosed a cardiac metastasis complicated by intraventricular thrombus (...) and pulmonary embolism.Cardiac metastasis from tongue carcinoma complicated by pulmonary embolism.After undergoing 2 cycles of palliative chemotherapy, the patient declined any further treatment.Patient died 3 months after the diagnosis of cardiac metastasis.Cardiac metastasis should be considered as a differential diagnosis in patients with a history of head and neck malignancy who present non-specific cardiac symptoms.

2017 Medicine

20. Tongue Necrosis Secondary to Giant Cell Arteritis: A Case Report and Literature Review Full Text available with Trip Pro

Tongue Necrosis Secondary to Giant Cell Arteritis: A Case Report and Literature Review Giant cell arteritis is a form of vasculitis involving the medium- and large-sized arteries that chiefly affects older people. Clinical findings are headache, jaw claudication, fever, pain, and thickening of the temporal artery. The most feared complication is visual loss due to impairment of the ophthalmic artery and posterior ciliary arteries. This a case report of an 85-year-old male presenting (...) with headache and jaw pain, who was admitted with tongue necrosis as an initial manifestation of giant cell arteritis. The necrotic area detached spontaneously after two weeks of therapy with corticosteroids and methotrexate. Reviewing the literature, our patient presented with clinical symptoms consistent with most reports, except for the fact of being male. Although unusual as an initial manifestation, tongue necrosis is an important alert for diagnosing giant cell arteritis. Early diagnosis and treatment

2017 Case reports in medicine

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