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Tissue Adhesive

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12561. A new tissue adhesive for laceration repair in children. (Abstract)

A new tissue adhesive for laceration repair in children. To determine the effectiveness of a new tissue adhesive, 2-Octylcyanoacrylate (2-OCA), for laceration repair, 83 children presenting to T.C. Thompson Children's Hospital Emergency Department with lacerations meeting eligibility requirements between February and June 1996 were randomized to receive 2-OCA or nonabsorbable sutures/staples. The length of time for repair was recorded. The length of time for laceration repair was decreased (2.9 (...) minutes 2-OCA vs 5.8 minutes suture/staple; p < 0.001), the parents' assessment of the pain felt by their children in the 2-OCA group was less, and the wounds closed with tissue adhesive had slightly lower cosmesis scores. 2-OCA is an acceptable alternative to conventional methods of wound repair with comparable cosmetic outcome.

1998 The Journal of pediatrics Controlled trial quality: uncertain

12562. Tissue adhesive versus suture wound repair at 1 year: randomized clinical trial correlating early, 3-month, and 1-year cosmetic outcome. (Abstract)

Tissue adhesive versus suture wound repair at 1 year: randomized clinical trial correlating early, 3-month, and 1-year cosmetic outcome. To compare the 1-year cosmetic outcome of wounds treated with octylcyanoacrylate tissue adhesive and monofilament sutures and to correlate the early, 3-month, and 1-year cosmetic outcomes.We prospectively randomized 136 cases of traumatic laceration to repair with octylcyanoacrylate tissue adhesive or 5-0 or smaller monofilament suture. A wound score (...) (intraclass correlation,.48; 95% CI, .30 to.63).One year after wound repair, no difference is noted in the cosmetic outcomes of traumatic lacerations treated with octylcyanoacrylate tissue adhesive and sutures. The assessment of wounds 3 months after injury and wound repair provides a good measure of long-term cosmetic outcome.

1998 Annals of Emergency Medicine Controlled trial quality: predicted high

12563. Application of tissue adhesives: rapid attainment of proficiency. Stony Brook Octylcyanoacrylate Study Group. (Abstract)

Application of tissue adhesives: rapid attainment of proficiency. Stony Brook Octylcyanoacrylate Study Group. To evaluate the 3-month cosmetic outcome following laceration repair with a new tissue adhesive, 2-octylcyanoacrylate, as a function of physician experience with this tissue adhesive.The authors prospectively enrolled consecutive patients >1 year of age with non-bite, non-crush-induced lacerations who presented <6 hours after injury and were treated with 2-octylcyanoacrylate. Structured (...) necessitated reclosure due to dehiscence. Neither occurred with the first application.The 3-month cosmetic appearance of wounds treated with 2-octylcyanoacrylate is equivalent to that with sutures and does not improve as physicians become more experienced with use of this tissue adhesive. These data suggest that physicians can develop competence in application of tissue adhesives with a brief training period.

1998 Academic Emergency Medicine Controlled trial quality: uncertain

12564. Tissue-specific homing receptor mediates lymphocyte adhesion to cytokine-stimulated lymph node high endothelial venule cells. Full Text available with Trip Pro

Tissue-specific homing receptor mediates lymphocyte adhesion to cytokine-stimulated lymph node high endothelial venule cells. Lymphocytes bind to high endothelial venule (HEV) cells as the first step in the migration of these cells into lymph nodes (LN) and Peyer's patches (PP). In this study we isolated and cultured HEV cells from rat LN and investigated the effects of cytokines on the adhesiveness of these cells for lymphocytes. The results showed that lymphocytes from thoracic duct, spleen (...) and LN adhered preferentially to the cultured LN HEV cells compared to cells isolated from the thymus and bone marrow. The adhesiveness of LN HEV cells for thoracic duct lymphocytes (TDL) was significantly increased in a dose- and time-dependent manner by pretreatment of the HEV cells with tumour necrosis factor-alpha (TNF-alpha), interferon-gamma (IFN-gamma) or interleukin-4 (IL-4). In contrast, pretreatment of HEV cells with IL-1, IL-6 or IL-7 did not alter the capacity of LN HEV cells to adhere

1991 Immunology

12565. Use of a tissue adhesive to repair fetal bodies after dissection. Full Text available with Trip Pro

Use of a tissue adhesive to repair fetal bodies after dissection. The repair of fetal bodies after dissection is extremely difficult because of the delicacy of the skin. A tissue adhesive, Histoacryl blue, was used to repair bodies that had been dissected either before or after immersion in formalin. The repairs were achieved rapidly and neatly. The technique was easy to learn and, providing the method of repair described was followed, there was no breakdown subsequently. The body cavities

1991 Journal of Clinical Pathology

12566. Comparison of effects of suture and cyanoacrylate tissue adhesive on bacterial counts in contaminated lacerations. Full Text available with Trip Pro

Comparison of effects of suture and cyanoacrylate tissue adhesive on bacterial counts in contaminated lacerations. We studied the effects of closing lacerations with suture or cyanoacrylate tissue adhesive on staphylococcal counts in inoculated guinea pig lacerations. Wounds closed with adhesive alone had lower counts than wounds containing suture material (P < 0.05). The results of a time-kill study were consistent with a bacteriostatic adhesive effect of the adhesive against Staphylococcus

1995 Antimicrobial Agents and Chemotherapy

12567. Cell adhesion to low-Mr proteins extractable from mineralized and soft connective tissues. Full Text available with Trip Pro

Cell adhesion to low-Mr proteins extractable from mineralized and soft connective tissues. Guanidinium chloride (4 M) containing proteinase inhibitors was used to extract proteins from porcine calvariae and long bones. The extracted proteins were separated on polyacrylamide slab gels and transferred electrophoretically to nitrocellulose strips. Proteins with cell-adhesion properties were identified by incubating the strips with cells and staining with Amido Black. In addition to binding (...) to fibronectin, both bone cells and fibroblast-like cells adhered to proteins of Mr approximately 30 000 and approximately 14 000-17 000. 4 M-Guanidinium chloride extracts of porcine skin and gingiva yielded cell-binding proteins with similar Mr values. These data suggest that these low-Mr proteins may have a general cell-adhesion function in both soft and mineralized connective tissues.

1985 Biochemical Journal

12568. Polarity determination in breast tissue: desmosomal adhesion, myoepithelial cells, and laminin 1 Full Text available with Trip Pro

Polarity determination in breast tissue: desmosomal adhesion, myoepithelial cells, and laminin 1 In all epithelial organs, apicobasal polarity determines functional integrity and contributes to the maintenance of tissue and organ specificity. In the breast, the functional unit is a polar double-layered tube consisting of luminal epithelial cells surrounded by myoepithelial cells and a basement membrane. It is far from clear how this double-layered structure is established and how polarity

2003 Breast Cancer Research

12569. Chemokines, chemokine receptors and adhesion molecules on different human endothelia: discriminating the tissue-specific functions that affect leucocyte migration Full Text available with Trip Pro

Chemokines, chemokine receptors and adhesion molecules on different human endothelia: discriminating the tissue-specific functions that affect leucocyte migration The selective accumulation of different leucocyte populations during inflammation is regulated by adhesion molecules and chemokines expressed by vascular endothelium. This study examined how chemokine production and the expression of adhesion molecules and chemokine receptors vary between endothelia from different vascular beds. Human (...) that it is the tissue-specific variations in endothelial chemokine secretion rather than variations in adhesion molecules that can explain the different patterns of inflammation and leucocyte traffic seen in non-lymphoid tissues.

2003 Clinical and experimental immunology

12570. Use of tissue adhesives in sport? A new application in international ice hockey Full Text available with Trip Pro

Use of tissue adhesives in sport? A new application in international ice hockey In the tough, competitive environment of international ice hockey, it is vital that a player who sustains a minor facial laceration is returned to play as soon as possible. A method of wound closure that is fast to apply, water resistant, and effective was sought. Dermabond, a cyanoacrylate tissue adhesive, was selected for use during the 2002 International Ice Hockey Federation World Championships for the closure (...) of selected facial wounds. The wounds were all closed using prescribed aseptic techniques. The results are presented and discussed. The tissue adhesive met the criteria set out.

2004 British Journal of Sports Medicine

12571. Coupling of the adhesive receptor CD11b/CD18 to functional enhancement of effector macrophage tissue factor response. Full Text available with Trip Pro

Coupling of the adhesive receptor CD11b/CD18 to functional enhancement of effector macrophage tissue factor response. Initiation and regulation of localized selective proteolysis is an important effector property of cells of macrophage (Mo) lineage. Among such effector responses is the induced expression of tissue factor (TF) by cells of Mo lineage. In characterizing the regulation of the Mo responses that may influence the magnitude of the effector phase of the cellular immune response, we (...) have identified a role for the cell surface adhesive receptor CD11b/CD18 (Mac-1, CR3) to amplify the induced TF response. Occupancy of CD11b/CD18 by MAb as surrogate ligands does not directly initiate a TF response. In contrast, after either T cell-derived cytokine or LPS as initial signals, engagement of CD11b/CD18 by MAb induces a two- to eight-fold functional enhancement of the TF response in murine and human Mo. This pathway of CD11b/CD18 enhancement of this Mo effector response was also

1991 Journal of Clinical Investigation

12572. Endoscopic Tissue Adhesive for Gastric Varices Full Text available with Trip Pro

Endoscopic Tissue Adhesive for Gastric Varices 2043520 1991 07 16 2013 11 21 0894-8569 3 3 1991 HPB surgery : a world journal of hepatic, pancreatic and biliary surgery HPB Surg Endoscopic tissue adhesive for gastric varices. 214-6 Johansen K K Harborview Medical Center, Seattle, Washington 98104. eng Journal Article United States HPB Surg 9002972 0894-8569 F8CEP82QNP Enbucrilate IM Enbucrilate therapeutic use Esophageal and Gastric Varices complications Esophagoscopy Gastrointestinal

1991 HPB Surgery

12573. Cyanoacrylate tissue adhesive. Full Text available with Trip Pro

Cyanoacrylate tissue adhesive. 1888415 1991 10 15 2018 11 13 0264-4924 8 2 1991 Jun Archives of emergency medicine Arch Emerg Med Cyanoacrylate tissue adhesive. 155-6 Burchett N N eng Case Reports Letter England Arch Emerg Med 8500828 0264-4924 0 Cyanoacrylates 0 Tissue Adhesives IM Aged Aged, 80 and over Cyanoacrylates therapeutic use Emergency Service, Hospital Female Humans Leg Injuries drug therapy Male Tissue Adhesives therapeutic use 1991 6 1 1991 6 1 0 1 1991 6 1 0 0 ppublish 1888415

1991 Archives of Emergency Medicine

12574. Use of cyanoacrylate tissue adhesive for closing facial lacerations in children. Full Text available with Trip Pro

Use of cyanoacrylate tissue adhesive for closing facial lacerations in children. 2511944 1990 01 24 2018 11 13 0959-8138 299 6706 1989 Oct 21 BMJ (Clinical research ed.) BMJ Use of cyanoacrylate tissue adhesive for closing facial lacerations in children. 1014 Watson D P DP Guy's Hospital, London. eng Journal Article England BMJ 8900488 0959-8138 0 Tissue Adhesives F8CEP82QNP Enbucrilate AIM IM BMJ. 1989 Nov 11;299(6709):1217-8 2513060 Child Child, Preschool Enbucrilate adverse effects (...) therapeutic use Facial Injuries therapy Humans Tissue Adhesives adverse effects therapeutic use Wound Healing 1989 10 21 1989 10 21 0 1 1989 10 21 0 0 ppublish 2511944 PMC1837909 J Postgrad Med. 1986 Apr;32(2):97-100 3761216

1989 BMJ : British Medical Journal

12575. Role of feces, necrotic tissue, and various blocking agents in the prevention of adhesions. Full Text available with Trip Pro

Role of feces, necrotic tissue, and various blocking agents in the prevention of adhesions. 2930295 1989 05 05 2018 11 13 0003-4932 209 4 1989 Apr Annals of surgery Ann. Surg. Role of feces, necrotic tissue, and various blocking agents in the prevention of adhesions. 502-3 Tsimoyiannis E C EC eng Letter United States Ann Surg 0372354 0003-4932 EC 1.15.1.1 Superoxide Dismutase AIM IM Animals Peritoneal Diseases prevention & control Rats Superoxide Dismutase pharmacology Tissue Adhesions

1989 Annals of Surgery

12576. Cyanoacrylate tissue adhesive and facial lacerations. Full Text available with Trip Pro

Cyanoacrylate tissue adhesive and facial lacerations. 2513060 1990 02 07 2018 11 13 0959-8138 299 6709 1989 Nov 11 BMJ (Clinical research ed.) BMJ Cyanoacrylate tissue adhesive and facial lacerations. 1217-8 eng Comment Letter England BMJ 8900488 0959-8138 0 Cyanoacrylates 0 Tissue Adhesives AIM IM BMJ. 1989 Oct 21;299(6706):1014 2511944 Cyanoacrylates therapeutic use Facial Injuries therapy Humans Tissue Adhesives therapeutic use 1989 11 11 1989 11 11 0 1 1989 11 11 0 0 ppublish 2513060

1989 BMJ : British Medical Journal

12577. Use of histoacryl tissue adhesive to manage an avulsed tooth. Full Text available with Trip Pro

Use of histoacryl tissue adhesive to manage an avulsed tooth. 2383702 1990 09 18 2018 11 13 0959-8138 301 6742 1990 Jul 07 BMJ (Clinical research ed.) BMJ Use of histoacryl tissue adhesive to manage an avulsed tooth. 20-1 McCabe M J MJ Accident and Emergency Department, Northwick Park Hospital, Middlesex. eng Case Reports Journal Article England BMJ 8900488 0959-8138 0 Tissue Adhesives F8CEP82QNP Enbucrilate AIM IM BMJ. 1990 Aug 18-25;301(6748):386-7 2400861 Adult Emergencies Enbucrilate (...) administration & dosage Hockey injuries Humans Incisor injuries Male Tissue Adhesives administration & dosage Tooth Avulsion surgery Tooth Replantation methods 1990 7 7 1990 7 7 0 1 1990 7 7 0 0 ppublish 2383702 PMC1663359 J Am Dent Assoc. 1986 Feb;112(2):224-30 3512655 Br Med J (Clin Res Ed). 1988 Mar 5;296(6623):719-20 3128390 Arch Emerg Med. 1988 Jun;5(2):110-2 3408528 Dent Update. 1988 Oct;15(8):332-5 3271702

1990 BMJ : British Medical Journal

12578. Cellular expression of lymphocyte function associated antigens and the intercellular adhesion molecule-1 in normal tissue. Full Text available with Trip Pro

Cellular expression of lymphocyte function associated antigens and the intercellular adhesion molecule-1 in normal tissue. A detailed immunohistological analysis of normal tissues for the distribution of lymphocyte function-associated antigens (LFA) and the intercellular adhesion molecule-1 (ICAM-1) showed several hitherto unrecognised patterns of LFA-3 and ICAM-1 expression. The widespread, but not ubiquitous, distribution of LFA-3 contrasted with the more restricted distribution of ICAM-1 (...) . Among epithelial cells, all tissues which were ICAM-1 positive were also LFA-3 positive with the single exception that thymic cortical epithelium, in contrast to previous reports, expressed only ICAM-1. It was striking that LFA-3 molecules were absent in some tissues which are considered to be sites of immunological privilege (such as brain and testis), suggesting an additional mechanism by which these microenvironments maintain immunological autonomy. Furthermore, the unexpected finding that LFA-3

1990 Journal of Clinical Pathology

12579. The role of feces, necrotic tissue, and various blocking agents in the prevention of adhesions. Full Text available with Trip Pro

The role of feces, necrotic tissue, and various blocking agents in the prevention of adhesions. Ischemic tissue and intraperitoneal bacteria have been ascribed an etiologic role in the production of intra-abdominal adhesions. To further elucidate the role of these stimuli and to evaluate the potential protective effect of various agents, peritonitis was induced in 160 Sprague-Dawley rats. The experiment was stratified into those animals with peritonitis plus necrotic tissue, solid feces, both (...) , or neither. The agents tested were a nonsteroidal anti-inflammatory (ibuprofen), free radical scavenger (SOD), and an anticoagulant (heparin). Death was less likely to occur in animals treated with heparin (3 of 40 vs. 12 of 40, p less than 0.01) or SOD (4 of 40 vs. 12 of 40, p less than 0.05). Ibuprofen did not increase survival in this model. Heparin protected against adhesions in animals with an ischemic ileum of limb and without solid feces. In animals with a nonischemic isolated segment of ileum

1988 Annals of Surgery

12580. The use of histoacryl tissue adhesive for the primary closure of scalp wounds. Full Text available with Trip Pro

The use of histoacryl tissue adhesive for the primary closure of scalp wounds. A prospective evaluation of Histoacryl tissue adhesive for the repair of simple scalp wounds is described. Fifty wounds were repaired using the adhesive and, on examination 5 days later, 49 wounds were fully healed, the remaining wound having only a small area of dehiscence. The advantage of this method of wound repair is discussed.

1988 Archives of Emergency Medicine

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