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Tissue Adhesive

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12561. A clinical trial of tissue adhesive (histoacryl) in skin closure of groin wounds. (Abstract)

A clinical trial of tissue adhesive (histoacryl) in skin closure of groin wounds. The use of tissue adhesives has been widely studied since the 1960s. Since then they have found use in specialties like plastic surgery, neurosurgery, ENT surgery and dental surgery. Several papers have reported their safe use, both clinically and experimentally, particularly of the newer homologue n-butyl/2-cyanoacrylate (Histoacryl). In this study 43 patients (46 wounds) whose operations involved a groin (...) that there is a place for tissue adhesives in skin closure for some general surgical wounds.

1989 The Medical journal of Malaysia Controlled trial quality: uncertain

12562. Laceration repair using a tissue adhesive in a children's emergency department. (Abstract)

Laceration repair using a tissue adhesive in a children's emergency department. To determine the effectiveness of a tissue adhesive, Histoacryl Blue (HAB), for laceration repair in children.Prospective, randomized clinical trial.A tertiary care pediatric emergency center at Egleston Children's Hospital.Children who presented for laceration repair between October 1994 and February 1995 were prospectively evaluated. Patients less than 1 or greater than 18 years of age, those with lacerations

1996 Pediatrics Controlled trial quality: uncertain

12563. [Evaluation of using fibrin tissue adhesive (Beriplast) and preparations of thrombin and adrenalin in injection hemostasis methods for gastric and duodenal ulcer hemorrhage. Randomized, prospective clinical trial]. (Abstract)

[Evaluation of using fibrin tissue adhesive (Beriplast) and preparations of thrombin and adrenalin in injection hemostasis methods for gastric and duodenal ulcer hemorrhage. Randomized, prospective clinical trial]. A prospective randomized trial involving 30 patients was performed to assess whether second-look endoscopy could improve the efficacy of injection therapy for bleeding peptic ulcers. The inclusion criteria were the presence of active arterial bleeding or a non-bleeding visible vessel

1997 Wiadomości lekarskie (Warsaw, Poland : 1960) Controlled trial quality: uncertain

12564. Long-term appearance of lacerations repaired using a tissue adhesive. (Abstract)

Long-term appearance of lacerations repaired using a tissue adhesive. Histoacryl Blue (HAB), a tissue adhesive, has been shown to decrease laceration repair time, cause less pain to the child, eliminate the need for suture removal, and result in a similar short-term cosmetic outcome compared with conventional suturing. Reports suggest that poor correlation can exist between the short-term and long-term cosmetic outcomes for lacerations repaired by conventional suturing. Therefore, this study

1997 Pediatrics Controlled trial quality: uncertain

12565. Prospective, randomized, controlled trial of tissue adhesive (2-octylcyanoacrylate) vs standard wound closure techniques for laceration repair. Stony Brook Octylcyanoacrylate Study Group. (Abstract)

Prospective, randomized, controlled trial of tissue adhesive (2-octylcyanoacrylate) vs standard wound closure techniques for laceration repair. Stony Brook Octylcyanoacrylate Study Group. To compare a new tissue adhesive, 2-octylcyanoacrylate, with standard wound closure techniques for the repair of traumatic lacerations.A prospective, randomized, controlled clinical trial enrolled consecutive patients > 1 year of age with non-bite, non-crush-induced lacerations who presented < 6 hours after

1998 Academic Emergency Medicine Controlled trial quality: uncertain

12566. Injection of fibrin tissue adhesive versus laser photocoagulation in the treatment of high-risk bleeding peptic ulcers: a controlled randomized study. (Abstract)

Injection of fibrin tissue adhesive versus laser photocoagulation in the treatment of high-risk bleeding peptic ulcers: a controlled randomized study. A controlled and randomized multicenter study was carried out in order to compare the efficacy of fibrin sealant and Nd:YAG laser photocoagulation in patients with high-risk arterial bleeding from peptic ulcers of the stomach and the small intestine.In four teaching hospitals, 53 patients presenting with either active arterial ulcer bleeding (...) (Forrest class 1 a) or a large visible vessel in the ulcer base (diameter over 2 mm, Forrest class 2 a) were treated with infiltration of epinephrine 1: 10,000 followed by the injection of fibrin tissue adhesive (n = 28), or with epinephrine plus laser photocoagulation (n = 25). Permanent hemostasis for at least seven days served as the principal end point; rebleeding, emergency surgery, and hospital mortality served as further end points.There were no significant differences between the study groups

1996 Endoscopy Controlled trial quality: uncertain

12567. A new tissue adhesive for laceration repair in children. (Abstract)

A new tissue adhesive for laceration repair in children. To determine the effectiveness of a new tissue adhesive, 2-Octylcyanoacrylate (2-OCA), for laceration repair, 83 children presenting to T.C. Thompson Children's Hospital Emergency Department with lacerations meeting eligibility requirements between February and June 1996 were randomized to receive 2-OCA or nonabsorbable sutures/staples. The length of time for repair was recorded. The length of time for laceration repair was decreased (2.9 (...) minutes 2-OCA vs 5.8 minutes suture/staple; p < 0.001), the parents' assessment of the pain felt by their children in the 2-OCA group was less, and the wounds closed with tissue adhesive had slightly lower cosmesis scores. 2-OCA is an acceptable alternative to conventional methods of wound repair with comparable cosmetic outcome.

1998 The Journal of pediatrics Controlled trial quality: uncertain

12568. Tissue adhesive versus suture wound repair at 1 year: randomized clinical trial correlating early, 3-month, and 1-year cosmetic outcome. (Abstract)

Tissue adhesive versus suture wound repair at 1 year: randomized clinical trial correlating early, 3-month, and 1-year cosmetic outcome. To compare the 1-year cosmetic outcome of wounds treated with octylcyanoacrylate tissue adhesive and monofilament sutures and to correlate the early, 3-month, and 1-year cosmetic outcomes.We prospectively randomized 136 cases of traumatic laceration to repair with octylcyanoacrylate tissue adhesive or 5-0 or smaller monofilament suture. A wound score (...) (intraclass correlation,.48; 95% CI, .30 to.63).One year after wound repair, no difference is noted in the cosmetic outcomes of traumatic lacerations treated with octylcyanoacrylate tissue adhesive and sutures. The assessment of wounds 3 months after injury and wound repair provides a good measure of long-term cosmetic outcome.

1998 Annals of Emergency Medicine Controlled trial quality: predicted high

12569. Application of tissue adhesives: rapid attainment of proficiency. Stony Brook Octylcyanoacrylate Study Group. (Abstract)

Application of tissue adhesives: rapid attainment of proficiency. Stony Brook Octylcyanoacrylate Study Group. To evaluate the 3-month cosmetic outcome following laceration repair with a new tissue adhesive, 2-octylcyanoacrylate, as a function of physician experience with this tissue adhesive.The authors prospectively enrolled consecutive patients >1 year of age with non-bite, non-crush-induced lacerations who presented <6 hours after injury and were treated with 2-octylcyanoacrylate. Structured (...) necessitated reclosure due to dehiscence. Neither occurred with the first application.The 3-month cosmetic appearance of wounds treated with 2-octylcyanoacrylate is equivalent to that with sutures and does not improve as physicians become more experienced with use of this tissue adhesive. These data suggest that physicians can develop competence in application of tissue adhesives with a brief training period.

1998 Academic Emergency Medicine Controlled trial quality: uncertain

12570. Tissue-specific homing receptor mediates lymphocyte adhesion to cytokine-stimulated lymph node high endothelial venule cells. Full Text available with Trip Pro

Tissue-specific homing receptor mediates lymphocyte adhesion to cytokine-stimulated lymph node high endothelial venule cells. Lymphocytes bind to high endothelial venule (HEV) cells as the first step in the migration of these cells into lymph nodes (LN) and Peyer's patches (PP). In this study we isolated and cultured HEV cells from rat LN and investigated the effects of cytokines on the adhesiveness of these cells for lymphocytes. The results showed that lymphocytes from thoracic duct, spleen (...) and LN adhered preferentially to the cultured LN HEV cells compared to cells isolated from the thymus and bone marrow. The adhesiveness of LN HEV cells for thoracic duct lymphocytes (TDL) was significantly increased in a dose- and time-dependent manner by pretreatment of the HEV cells with tumour necrosis factor-alpha (TNF-alpha), interferon-gamma (IFN-gamma) or interleukin-4 (IL-4). In contrast, pretreatment of HEV cells with IL-1, IL-6 or IL-7 did not alter the capacity of LN HEV cells to adhere

1991 Immunology

12571. Use of a tissue adhesive to repair fetal bodies after dissection. Full Text available with Trip Pro

Use of a tissue adhesive to repair fetal bodies after dissection. The repair of fetal bodies after dissection is extremely difficult because of the delicacy of the skin. A tissue adhesive, Histoacryl blue, was used to repair bodies that had been dissected either before or after immersion in formalin. The repairs were achieved rapidly and neatly. The technique was easy to learn and, providing the method of repair described was followed, there was no breakdown subsequently. The body cavities

1991 Journal of Clinical Pathology

12572. Comparison of effects of suture and cyanoacrylate tissue adhesive on bacterial counts in contaminated lacerations. Full Text available with Trip Pro

Comparison of effects of suture and cyanoacrylate tissue adhesive on bacterial counts in contaminated lacerations. We studied the effects of closing lacerations with suture or cyanoacrylate tissue adhesive on staphylococcal counts in inoculated guinea pig lacerations. Wounds closed with adhesive alone had lower counts than wounds containing suture material (P < 0.05). The results of a time-kill study were consistent with a bacteriostatic adhesive effect of the adhesive against Staphylococcus

1995 Antimicrobial Agents and Chemotherapy

12573. Cell adhesion to low-Mr proteins extractable from mineralized and soft connective tissues. Full Text available with Trip Pro

Cell adhesion to low-Mr proteins extractable from mineralized and soft connective tissues. Guanidinium chloride (4 M) containing proteinase inhibitors was used to extract proteins from porcine calvariae and long bones. The extracted proteins were separated on polyacrylamide slab gels and transferred electrophoretically to nitrocellulose strips. Proteins with cell-adhesion properties were identified by incubating the strips with cells and staining with Amido Black. In addition to binding (...) to fibronectin, both bone cells and fibroblast-like cells adhered to proteins of Mr approximately 30 000 and approximately 14 000-17 000. 4 M-Guanidinium chloride extracts of porcine skin and gingiva yielded cell-binding proteins with similar Mr values. These data suggest that these low-Mr proteins may have a general cell-adhesion function in both soft and mineralized connective tissues.

1985 Biochemical Journal

12574. Polarity determination in breast tissue: desmosomal adhesion, myoepithelial cells, and laminin 1 Full Text available with Trip Pro

Polarity determination in breast tissue: desmosomal adhesion, myoepithelial cells, and laminin 1 In all epithelial organs, apicobasal polarity determines functional integrity and contributes to the maintenance of tissue and organ specificity. In the breast, the functional unit is a polar double-layered tube consisting of luminal epithelial cells surrounded by myoepithelial cells and a basement membrane. It is far from clear how this double-layered structure is established and how polarity

2003 Breast Cancer Research

12575. Chemokines, chemokine receptors and adhesion molecules on different human endothelia: discriminating the tissue-specific functions that affect leucocyte migration Full Text available with Trip Pro

Chemokines, chemokine receptors and adhesion molecules on different human endothelia: discriminating the tissue-specific functions that affect leucocyte migration The selective accumulation of different leucocyte populations during inflammation is regulated by adhesion molecules and chemokines expressed by vascular endothelium. This study examined how chemokine production and the expression of adhesion molecules and chemokine receptors vary between endothelia from different vascular beds. Human (...) that it is the tissue-specific variations in endothelial chemokine secretion rather than variations in adhesion molecules that can explain the different patterns of inflammation and leucocyte traffic seen in non-lymphoid tissues.

2003 Clinical and experimental immunology

12576. Use of tissue adhesives in sport? A new application in international ice hockey Full Text available with Trip Pro

Use of tissue adhesives in sport? A new application in international ice hockey In the tough, competitive environment of international ice hockey, it is vital that a player who sustains a minor facial laceration is returned to play as soon as possible. A method of wound closure that is fast to apply, water resistant, and effective was sought. Dermabond, a cyanoacrylate tissue adhesive, was selected for use during the 2002 International Ice Hockey Federation World Championships for the closure (...) of selected facial wounds. The wounds were all closed using prescribed aseptic techniques. The results are presented and discussed. The tissue adhesive met the criteria set out.

2004 British Journal of Sports Medicine

12577. Coupling of the adhesive receptor CD11b/CD18 to functional enhancement of effector macrophage tissue factor response. Full Text available with Trip Pro

Coupling of the adhesive receptor CD11b/CD18 to functional enhancement of effector macrophage tissue factor response. Initiation and regulation of localized selective proteolysis is an important effector property of cells of macrophage (Mo) lineage. Among such effector responses is the induced expression of tissue factor (TF) by cells of Mo lineage. In characterizing the regulation of the Mo responses that may influence the magnitude of the effector phase of the cellular immune response, we (...) have identified a role for the cell surface adhesive receptor CD11b/CD18 (Mac-1, CR3) to amplify the induced TF response. Occupancy of CD11b/CD18 by MAb as surrogate ligands does not directly initiate a TF response. In contrast, after either T cell-derived cytokine or LPS as initial signals, engagement of CD11b/CD18 by MAb induces a two- to eight-fold functional enhancement of the TF response in murine and human Mo. This pathway of CD11b/CD18 enhancement of this Mo effector response was also

1991 Journal of Clinical Investigation

12578. Endoscopic Tissue Adhesive for Gastric Varices Full Text available with Trip Pro

Endoscopic Tissue Adhesive for Gastric Varices 2043520 1991 07 16 2013 11 21 0894-8569 3 3 1991 HPB surgery : a world journal of hepatic, pancreatic and biliary surgery HPB Surg Endoscopic tissue adhesive for gastric varices. 214-6 Johansen K K Harborview Medical Center, Seattle, Washington 98104. eng Journal Article United States HPB Surg 9002972 0894-8569 F8CEP82QNP Enbucrilate IM Enbucrilate therapeutic use Esophageal and Gastric Varices complications Esophagoscopy Gastrointestinal

1991 HPB Surgery

12579. Cyanoacrylate tissue adhesive. Full Text available with Trip Pro

Cyanoacrylate tissue adhesive. 1888415 1991 10 15 2018 11 13 0264-4924 8 2 1991 Jun Archives of emergency medicine Arch Emerg Med Cyanoacrylate tissue adhesive. 155-6 Burchett N N eng Case Reports Letter England Arch Emerg Med 8500828 0264-4924 0 Cyanoacrylates 0 Tissue Adhesives IM Aged Aged, 80 and over Cyanoacrylates therapeutic use Emergency Service, Hospital Female Humans Leg Injuries drug therapy Male Tissue Adhesives therapeutic use 1991 6 1 1991 6 1 0 1 1991 6 1 0 0 ppublish 1888415

1991 Archives of Emergency Medicine

12580. Use of cyanoacrylate tissue adhesive for closing facial lacerations in children. Full Text available with Trip Pro

Use of cyanoacrylate tissue adhesive for closing facial lacerations in children. 2511944 1990 01 24 2018 11 13 0959-8138 299 6706 1989 Oct 21 BMJ (Clinical research ed.) BMJ Use of cyanoacrylate tissue adhesive for closing facial lacerations in children. 1014 Watson D P DP Guy's Hospital, London. eng Journal Article England BMJ 8900488 0959-8138 0 Tissue Adhesives F8CEP82QNP Enbucrilate AIM IM BMJ. 1989 Nov 11;299(6709):1217-8 2513060 Child Child, Preschool Enbucrilate adverse effects (...) therapeutic use Facial Injuries therapy Humans Tissue Adhesives adverse effects therapeutic use Wound Healing 1989 10 21 1989 10 21 0 1 1989 10 21 0 0 ppublish 2511944 PMC1837909 J Postgrad Med. 1986 Apr;32(2):97-100 3761216

1989 BMJ : British Medical Journal

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