How to Trip Rapid Review

Step 1: Select articles relevant to your search (remember the system is only optimised for single intervention studies)

Step 2: press

Step 3: review the result, and maybe amend the or if you know better! If we're unsure of the overall sentiment of the trial we will display the conclusion under the article title. We then require you to tell us what the correct sentiment is.

12,600 results for

Tissue Adhesive

by
...
Latest & greatest
Alerts

Export results

Use check boxes to select individual results below

SmartSearch available

Trip's SmartSearch engine has discovered connected searches & results. Click to show

21. Neutrophil adhesion is a prerequisite for antibody-mediated proteolytic tissue damage in experimental epidermolysis bullosa acquisita. (PubMed)

Neutrophil adhesion is a prerequisite for antibody-mediated proteolytic tissue damage in experimental epidermolysis bullosa acquisita. Although uncontrolled proteolytic activity mediated by activated neutrophils is a major reason for tissue damage, therapeutic approaches using protease inhibitors are inefficient. Here, we investigated the role of the immune complex-induced neutrophil adhesion and protease release in tissue damage. We show both in vitro and in vivo that immune complex-mediated (...) neutrophil adhesion to the target tissue depends on β2 integrins. Without affecting elastase or reactive oxygen species release, blocking of adhesion drastically inhibited tissue damage in an experimental model of autoantibody-mediated skin blistering disease. By using a cell-bound fluorescent resonance energy transfer-based elastase sensor, we detected elastase enzyme activity on the surface of adherent cells resistant to protease inhibitors. Inhibitor resistance was lost by CD18 blockade or deficiency

2018 Journal of Investigative Dermatology

22. Preoperative Evaluation of Tumor Adhesion to Adjacent Brain Tissue in Patients with Meningioma with BSMI Method and Its Comparison with the Width of Edema Around Tumor (PubMed)

Preoperative Evaluation of Tumor Adhesion to Adjacent Brain Tissue in Patients with Meningioma with BSMI Method and Its Comparison with the Width of Edema Around Tumor Background: This study aims to investigate the ability of BSMI, to preoperative evaluation of tumor adhesion to adjacent brain tissue in patients with meningioma and comparing this method to the width of edema around tumor, using surgery findings as the reference standard. Methods: Thirty patients with meningioma brain tumor who (...) evaluated 23 (76.7%) as adhesion (+) and 7 (23.3%) as adhesion (-).The sensitivity was moderate but the specificity was high, at 52.17% and 85.71%, respectively. Other criteria such as precision and accuracy were 62.31% and 60%, respectively. Conclusions: BSMI evaluated adhesion of the tumor to the adjacent brain tissue with high-accuracy prior to surgery. This method was more effective than Edema method in evaluating adhesion between meningioma and the brain.Creative Commons Attribution License

Full Text available with Trip Pro

2018 Asian Pacific journal of cancer prevention : APJCP

23. Dia1-dependent adhesions are required by epithelial tissues to initiate invasion (PubMed)

Dia1-dependent adhesions are required by epithelial tissues to initiate invasion Developing tissues change shape and tumors initiate spreading through collective cell motility. Conserved mechanisms by which tissues initiate motility into their surroundings are not known. We investigated cytoskeletal regulators during collective invasion by mouse tumor organoids and epithelial Madin-Darby canine kidney (MDCK) acini undergoing branching morphogenesis in collagen. Use of the broad-spectrum formin (...) and generated large traction forces, whereas Dia1-depleted acini exhibited unstable adhesions with minimal collagen deformation and lower force generation. This work identifies Dia1 as an essential regulator of tissue shape changes through its role in stabilizing focal adhesions.© 2018 Fessenden et al.

Full Text available with Trip Pro

2018 The Journal of cell biology

24. Diathermy to tissue adhesives for retinal tears: The future of retinal reattachment surgery (PubMed)

Diathermy to tissue adhesives for retinal tears: The future of retinal reattachment surgery 29380767 2018 04 03 2018 12 02 1998-3689 66 2 2018 02 Indian journal of ophthalmology Indian J Ophthalmol Diathermy to tissue adhesives for retinal tears: The future of retinal reattachment surgery. 244-245 10.4103/ijo.IJO_1198_17 Rishi Ekta E Shri Bhagwan Mahavir Vitreoretinal Services, Medical Reasearch Foundation, Chennai, Tamil Nadu, India. Singh Niharika N Shri Bhagwan Mahavir Vitreoretinal Services (...) , Medical Reasearch Foundation, Chennai, Tamil Nadu, India. eng Journal Article Comment India Indian J Ophthalmol 0405376 0301-4738 0 Tissue Adhesives IM Indian J Ophthalmol. 2018 Feb;66(2):238-243 29380766 Diathermy Humans Retinal Detachment surgery Retinal Perforations Scleral Buckling Tissue Adhesives Vitreous Body 2018 1 31 6 0 2018 1 31 6 0 2018 4 4 6 0 ppublish 29380767 IndianJOphthalmol_2018_66_2_244_224071 10.4103/ijo.IJO_1198_17 PMC5819104 Semin Ophthalmol. 1995 Mar;10(1):74-8 10155700 Indian J

Full Text available with Trip Pro

2018 Indian journal of ophthalmology

25. Tumor-suppressing miR-141 gene complex-loaded tissue-adhesive glue for the locoregional treatment of hepatocellular carcinoma (PubMed)

Tumor-suppressing miR-141 gene complex-loaded tissue-adhesive glue for the locoregional treatment of hepatocellular carcinoma microRNAs (miRNAs) regulate gene expression post-transcriptionally and have been extensively tested as therapeutic molecules against several human diseases. In vivo delivery of miRNAs needs to satisfy the following conditions: safety, efficiency, and long-term therapeutic effectiveness. To satisfy these conditions, we developed a tissue-adhesive nucleotide-polymer (...) regulated the target genes including MAP4K4, TM4SF1, KEAP1, HDGF, and TIAM1 and finally induced apoptosis of cancer tissues. Conclusion: Here, we show that NPX-glue delivers therapeutic miR-141 to solid tumors in a safe, stable, and long-term manner and prove that locoregional treatment of HCC is possible using the NPX-glue system.

Full Text available with Trip Pro

2018 Theranostics

26. Antibacterial and biodegradable tissue nano-adhesives for rapid wound closure (PubMed)

Antibacterial and biodegradable tissue nano-adhesives for rapid wound closure Although various organic tissue adhesives designed to facilitate would healing are gaining popularity in diverse clinical applications, they present significant inherent limitations, such as rejection, infections, toxicity and/or excessive swelling. It is highly desirable to develop efficient, biocompatible and anti-bacterial tissue adhesives for skin wound healing.Inspired by the fact that inorganic nanoparticles can (...) directly glue tissues through the "nanobridging effect", herein disulfide bond-bridged nanosilver-decorated mesoporous silica nanoparticles (Ag-MSNs) was constructed as an effective and safe tissue adhesive with antibacterial and degradable properties for wound closure and healing.Ag-MSNs was fabricated by controlled reduce of ultrasmall nanosilvers onto the both surface and large pore of biodegradable MSNs. The obtained MSNs were characterized by transmission electron microscopy, Fourier transform

Full Text available with Trip Pro

2018 International journal of nanomedicine

27. Differential tissue growth and cell adhesion alone drive early tooth morphogenesis: An ex vivo and in silico study (PubMed)

Differential tissue growth and cell adhesion alone drive early tooth morphogenesis: An ex vivo and in silico study From gastrulation to late organogenesis animal development involves many genetic and bio-mechanical interactions between epithelial and mesenchymal tissues. Ectodermal organs, such as hairs, feathers and teeth are well studied examples of organs whose development is based on epithelial-mesenchymal interactions. These develop from a similar primordium through an epithelial folding (...) , differential tissue growth and differential cell adhesion, were enough, in the model, for the development of the 3D morphology of the early tooth germ. This was largely determined by the length and direction of growth of the cervical loops, lateral folds of the enamel epithelium. The formation of these cervical loops was found to require accelerated epithelial growth relative to other tissues and their direction of growth depended on specific differential adhesion between the three tooth tissues. These two

Full Text available with Trip Pro

2018 PLoS computational biology

28. Fibrin tissue adhesive versus nasal packing in endoscopic nasal surgery: a systematic review and meta-analysis. (PubMed)

Fibrin tissue adhesive versus nasal packing in endoscopic nasal surgery: a systematic review and meta-analysis. It has been proposed that fibrin tissue adhesive (FTA) can act as an effective alternative to nasal packing in managing the postoperative symptoms of endoscopic nasal surgery.MEDLINE, Embase, Cochrane Library, The Cumulative Index to Nursing and Allied Health Literature and ClinicalTrials.gov were searched for randomised controlled trials comparing FTA with nasal packing in endoscopic (...) nasal surgery. The primary outcome of interest was bleeding; secondary outcomes included pain, nasal obstruction, infection, adhesions and the formation of granulation tissue. All trials underwent a risk of bias assessment, and a meta-analysis was performed using a random effects model.315 studies were found, of which four were eligible for inclusion (n = 152). Bleeding was reported in all, with the meta-analysis favouring the packing group, although this was not significant. Nasal obstruction

Full Text available with Trip Pro

2018 Rhinology

29. Allergic Contact Dermatitis due to VenaSeal Tissue Adhesive. (PubMed)

Allergic Contact Dermatitis due to VenaSeal Tissue Adhesive. 30582174 2019 01 31 1600-0536 2018 Dec 24 Contact dermatitis Contact Derm. Allergic contact dermatitis caused by VenaSeal tissue adhesive. 10.1111/cod.13206 Watts Timothy J TJ https://orcid.org/0000-0002-5488-4513 Department of Adult Allergy, Guy's and St Thomas' NHS Foundation Trust, London, UK. Thursfield David D Department of Adult Allergy, Guy's and St Thomas' NHS Foundation Trust, London, UK. Haque Rubaiyat R Department of Adult

2018 Contact Dermatitis

30. A comparison of aesthetic outcome between tissue adhesive and subcuticular suture in thyroidectomy wound closure in a multiracial country: A randomized controlled trial. (PubMed)

A comparison of aesthetic outcome between tissue adhesive and subcuticular suture in thyroidectomy wound closure in a multiracial country: A randomized controlled trial. Monofilament sutures, both absorbable and non-absorbable, have been used for wound closure. Tissue adhesive has been used in closure of clean, low tension wounds. However, there have been very few published studies on the aesthetic outcomes in neck surgeries. The aim of this study is to compare the patients' and doctors (...) ' satisfaction scores in the aesthetic outcome between both methods of closure of thyroidectomy wounds using validated scoring systems.A double-blinded randomised controlled trial comparing the aesthetic outcome between tissue adhesive and conventional suture was conducted among patients undergoing thyroid and parathyroid surgeries. Ninety-six patients were randomised into two treatment groups. Patients' wounds were scored by an independent observer using the SBSES score at 6 weeks postoperatively

Full Text available with Trip Pro

2018 Asian Journal of Surgery Controlled trial quality: uncertain

31. Performance of Universal Adhesive in Primary Molars After Selective Removal of Carious Tissue: An 18-Month Randomized Clinical Trial. (PubMed)

Performance of Universal Adhesive in Primary Molars After Selective Removal of Carious Tissue: An 18-Month Randomized Clinical Trial. To evaluate the 18-month clinical performance of a universal adhesive, applied under different adhesion strategies, after selective carious tissue removal in primary molars.Forty-four subjects (five to 10 years old) contributed with 90 primary molars presenting moderately deep dentin carious lesions on occlusal or occluso-proximal surfaces, which were randomly (...) ).Estimated survival rates of the restorations were 100 percent, 100 percent, 90.6 percent, and 81.4 percent at one, six, 12, and 18 months, respectively. The adhesion strategy did not influence the restorations' longevity (P=0.06; 72.2 percent and 89.7 percent with etch-and-rinse and self-etch mode, respectively).Self-etch and etch-and-rinse strategies did not influence the clinical behavior of universal adhesive used in primary molars after selective carious tissue removal; although there was a tendency

2018 Pediatric dentistry Controlled trial quality: uncertain

32. The Effectiveness of Applying Soft Tissue Bonding Adhesive Composed of 2-Ethyl Cyanoacrylate to Epidural Catheter Fixations Using Film Dressings: An Open-Label, Randomized, Parallel-Group Comparative Study. (PubMed)

The Effectiveness of Applying Soft Tissue Bonding Adhesive Composed of 2-Ethyl Cyanoacrylate to Epidural Catheter Fixations Using Film Dressings: An Open-Label, Randomized, Parallel-Group Comparative Study. Insufficient fixation of an epidural catheter may result in migration of the catheter and eventual catheter failure. However, the best fixation method remains to be established. Aron Alpha A (2-ethyl cyanoacrylate) adhesive is approved for clinical use and can be used for surgical adhesion (...) to both skin and blood vessels. We hypothesized that the addition of Aron Alpha A adhesive to film dressing would result in consistent and dependable catheter fixation.In this study, 58 women who were scheduled for cesarean delivery under spinal and epidural anesthesia were recruited. Patients were randomly assigned to a control or treatment group. In the control group, the catheter was fixed solely by film dressing. In the treatment group, a small amount of Aron Alpha A was applied at 2 sites along

2018 Anesthesia and Analgesia Controlled trial quality: uncertain

33. Extracorporeal membrane oxygenation line-associated complications: in vitro testing of cyanoacrylate tissue adhesive and securement devices to prevent infection and dislodgement (PubMed)

Extracorporeal membrane oxygenation line-associated complications: in vitro testing of cyanoacrylate tissue adhesive and securement devices to prevent infection and dislodgement Extracorporeal membrane oxygenation (ECMO) delivers cardiac and/or respiratory support to critically ill patients who have failed conventional medical therapies. If the large-bore cannulas used to deliver ECMO become infected or dislodged, the patient consequences can be catastrophic. ECMO cannula-related infection has (...) been reported to be double the rate of other vascular devices (7.1 vs 3.4 episodes/1000 ECMO days respectively). The aim of this study was to assess the ability of cyanoacrylate tissue adhesive (TA) to inhibit bacterial growth at the ECMO cannulation site, and the effectiveness of TA and securement devices in securing ECMO cannulas and tubing.This in vitro study tested the (1) antimicrobial qualities of TA against standard transparent dressing with ECMO cannula; (2) chemical compatibility between

Full Text available with Trip Pro

2018 Intensive care medicine experimental

35. Randomised, placebo controlled, double blind trial: Topical lidocaine?epinephrine?tetracaine is effective in reducing pain during laceration repair with tissue adhesive in children

Randomised, placebo controlled, double blind trial: Topical lidocaine?epinephrine?tetracaine is effective in reducing pain during laceration repair with tissue adhesive in children Topical lidocaine–epinephrine–tetracaine is effective in reducing pain during laceration repair with tissue adhesive in children | Evidence-Based Nursing We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn (...) laceration repair with tissue adhesive in children Article Text Nursing issues Randomised, placebo controlled, double blind trial Topical lidocaine–epinephrine–tetracaine is effective in reducing pain during laceration repair with tissue adhesive in children Ron Berant , Dennis Scolnik Statistics from Altmetric.com Commentary on: Harman S , Zemek R , Duncan MJ , et al . Efficacy of pain control with topical lidocaine-epinephrine-tetracaine during laceration repair with tissue adhesive in children

2014 Evidence-Based Nursing

36. Are Tissue Adhesives an Acceptable Alternative For Simple Lacerations?

Are Tissue Adhesives an Acceptable Alternative For Simple Lacerations? SystematicReviewSnapshot TAKE-HOME MESSAGE Simple lacerations closed with tissue adhesives have similar cosmetic results compared with those obtained with standard wound closure. METHODS DATA SOURCES The authors searched the Cochrane Wounds Group Specialized Trials Register (October 2007), the Co- chrane Central Register of Con- trolled Trials (Cochrane Library Issue 3, 2007), MEDLINE (1950 to 2007), EMBASE (1980 to 2007 (...) ), CINAHL (1982 to 2007), Web of Science– Science Citation Index (1975 to 2007), 7 clinical trial registries, and reference lists of articles. Experts in the ?eld and product manufacturers were also contacted to retrieve per- tinent data from ongoing, unpub- lished, or published trials not found in the electronic search. STUDY SELECTION All randomized controlled trials were included that compared tissue adhe- sives with standard wound closure or one tissue adhesive compared with another tissue adhesive

2011 Annals of Emergency Medicine Systematic Review Snapshots

37. Prophylactic Use of Antibiotics in Endoscopic Injection of Tissue Adhesive in Gastric Varices

Prophylactic Use of Antibiotics in Endoscopic Injection of Tissue Adhesive in Gastric Varices Prophylactic Use of Antibiotics in Endoscopic Injection of Tissue Adhesive in Gastric Varices - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one (...) or more studies before adding more. Prophylactic Use of Antibiotics in Endoscopic Injection of Tissue Adhesive in Gastric Varices (PUoA-EIoTA) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT03045783 Recruitment Status : Active, not recruiting First Posted : February 7, 2017 Last Update Posted

2017 Clinical Trials

38. Long-Term Outcome of Pediatric Traumatic Wound Repair: Suture Versus Tissue Adhesive

Long-Term Outcome of Pediatric Traumatic Wound Repair: Suture Versus Tissue Adhesive Long-Term Outcome of Pediatric Traumatic Wound Repair: Suture Versus Tissue Adhesive - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before (...) adding more. Long-Term Outcome of Pediatric Traumatic Wound Repair: Suture Versus Tissue Adhesive The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03080467 Recruitment Status : Recruiting First Posted : March 15, 2017 Last

2017 Clinical Trials

39. Native paraneurial tissue and paraneurial adhesions alter nerve strain distribution in rat sciatic nerves. (PubMed)

Native paraneurial tissue and paraneurial adhesions alter nerve strain distribution in rat sciatic nerves. Paraneurial adhesions have been implicated in the pathological progression of entrapment neuropathies. Surgical decompression of adhesions is often performed, with the intent of restoring nerve kinematics. The normal counterpart of adhesions, native paraneurium, is also thought to influence nerve deformation and mobility. However, influences of native or abnormal paraneurial structures (...) on nerve kinematics have not been investigated. We measured regional strains in rat sciatic nerves before and immediately after decompression of native paraneurial tissue, and before and after decompression of abnormal paraneurial adhesions, which formed within 6 weeks of the initial decompression. Strain was significantly higher in the distal-femoral than in the mid-femoral region of the nerve before either decompression. Decompression of native and abnormal paraneurial tissue removed this regional

2017 Journal of Hand Surgery - European

40. Wound closure and tissue adhesives in clear corneal incision cataract surgery. (PubMed)

Wound closure and tissue adhesives in clear corneal incision cataract surgery. Achieving secure wound closure in clear corneal incision cataract surgery remains highly desired for its role in reducing infection risk and leak-related complications, including hypotony, corneal edema, and lens dislocation. Although classic techniques of stromal hydration or wound suturing represent traditional approaches, the introduction of newer and more effective ocular surface adhesives has increased (...) the options that are available. This review aims to provide an update on the peer-reviewed literature regarding wound closure and the currently available and investigational tissue adhesives used to seal clear corneal incisions in cataract surgery.Stromal hydration and sutured closure of clear corneal incisions remain viable options for wound closure. Wound sealants, particularly polyethylene glycol (PEG)-based hydrogels, have been found to provide watertight wound seal with less foreign-body sensation

2017 Current Opinion in Ophthalmology

To help you find the content you need quickly, you can filter your results via the categories on the right-hand side >>>>