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the evaluation of the psoriasis vulgaris (e.g., atopic dermatitis, contact dermatitis, tineacorporis). Presence of pigmentation, extensive scarring, pigmented lesions, or sunburn in the treatment areas that could interfere with the rating of efficacy parameters. History of psoriasis unresponsive to topical treatments. History of hypersensitivity to any component of the Test or Reference product. Current or past history of hypercalcemia, calcium metabolism disorder, vitamin D toxicity, severe renal
disease he was also diagnosed as having disseminated severe tinea mannum, tineacorporis and tinea cruris; onychomycosis, skin eczema and psoriasis. After a prolonged course of anti-fungal therapy, his skin lesions as well as his nephrotic syndrome recovered completely. Follow up after 7 months without any anti-fungal or immunosuppression showed no skin or renal recurrence. We assume that the renal disease was related to the pre-existing cutaneous cryptococcosis, aggravated by immunosuppression
%) and August (16.2%). The most common clinical type of M. gypseum infection was tineacorporis (38.4%).M. gypseum infection shows very low incidence but still remains around us until recent years. We should keep in mind the characteristics of M. gypseum.
: Have a clinical diagnosis of a dermatological condition other that atopic dermatitis or psoriasis (such as contact dermatitis, cutaneous lymphoma, tineacorpori's, etc.), or have non plaque forms of psoriasis (for example, erythrodermic, guttate, or pustular), or have bacterial infections of the skin, including impetigo or abscesses. Have a history of skin cancer or have received treatment (chemotherapy, radiation, immune suppressant medications) for any type of cancer within the last 6 months
bacteria were the leading causes. Infectious diseases with dermatological manifestations, such as impetigo, leptospirosis, measles, dengue fever, tineacorporis, malaria, and leishmaniasis, are important causes of morbidity among flood-afflicted individuals. Insect bites and stings, and parasite infestations such as scabies and cutaneous larva migrans are also frequently observed. Inflammatory conditions including irritant contact dermatitis are among the leading dermatological conditions
Expert Consensus on The Management of Dermatophytosis in India (ECTODERM India). Dermatophytosis management has become an important public health issue, with a large void in research in the area of disease pathophysiology and management. Current treatment recommendations appear to lose their relevance in the current clinical scenario. The objective of the current consensus was to provide an experience-driven approach regarding the diagnosis and management of tineacorporis, cruris (...) , recurrent, relapse, recalcitrant and multisite tinea cases. Topical monotherapy was recommended for naïve tinea cruris and corporis (localised) cases, while a combination of systemic and topical antifungals was recommended for naïve and recalcitrant tinea pedis, extensive lesions of corporis and recalcitrant cases of cruris and corporis. Because of the anti-inflammatory, antibacterial and broad spectrum activity, topical azoles should be preferred. Terbinafine and itraconazole should be the preferred
also got tineacorporis on her trunk since she was 10 years old. Chrysosporium keratinophilum was isolated from the tissue on the neck and scales on the trunk, respectively. The patient showed satisfactory response to itraconazole therapy, although she discontinued the follow-up.
) were used for direct microscopy and culture. All the culture-positive samples were then subjected to amplification of the internal transcribed spacer (ITS) of the nuclear rDNA followed by a restriction fragment length polymorphism (RFLP) assay to verify the causative agents.The infection was confirmed in 90 (44.3%) males and 113 (55.7%) females. The most common type of dermatophytoses was tinea cruris (42.9%), followed by tinea pedis (20.2%), tineacorporis (11.3%), tinea unguium (7.4%), tinea (...) faciei (6.9%), tinea manuum (6.4%), and tinea capitis (4.9%). ITS-RFLP based of the identification of isolates, showed that the infections were significantly associated with anthropophilic species, of Trichophyton rubrum (41.9%), Epidermophyton floccosum (19.7%), T. tonsurans (5.4%), and T.violaceum (2%). Other causative agents were T. interdigitale (22.6%), Microsporum canis (4.9%), T. verrucosum (2.5%), and M. gypseum (1%).The higher prevalence of T. rubrum, as the agent of dermatophytoses, than
Infection by Microsporum canis in Paediatric Patients: A Veterinary Perspective Microsporum canis is a dermatophyte fungus of which cats and dogs are recognized as the natural hosts. M. canis is also easily transmitted to humans, causing lesions to the glabrous skin (tineacorporis) and to the head (tinea capitis). The present study describes some cases of infection with M. canis in children from a veterinary perspective, highlighting some important features of this clinical entity (e.g
diffusion (ABDD) method against Clotrimazole, Miconazole, Fluconazole, and Griseofulvin. Data were analyzed via SPSS 16, using Chi square and a screening test (cross-tabulation method).A total of 110 patients of dermatophytosis were studied. The patients were clinically diagnosed and mycologically confirmed as having tinea capitis (49), tineacorporis (30), tinea pedis (16), tinea cruris (9), or tinea barbae (6). The dermatophytes isolates belonged to 4 species: Microsporum canis 58 (52.7%), Microsporum (...) Isolation, Identification, and In Vitro Antifungal Susceptibility Testing of Dermatophytes from Clinical Samples at Sohag University Hospital in Egypt The objective of this study was to isolate, identify, and explore the in-vitro antifungal susceptibility pattern of dermatophytes isolated from clinically suspected cases of dermatophytosis (tinea infections) attending the Dermatology Outpatient Clinic.This study was conducted at Sohag University Hospital from December 2014 to December 2015
Efficacy and tolerability of topical sertaconazole versus topical terbinafine in localized dermatophytosis: A randomized, observer-blind, parallel group study. Epidermal dermatophyte infections most commonly manifest as tineacorporis or tinea cruris. Topical azole antifungals are commonly used in their treatment but literature suggests that most require twice-daily application and provide lower cure rates than the allylamine antifungal terbinafine. We conducted a head-to-head comparison (...) topical sertaconazole is as effective as terbinafine in localized tinea infections.
is close to the highest standard concentration for drinking water, it can be used in chronic dermatitis, psoriasis, burns, and allergy. Furthermore, the antibacterial and antifungal effects of sulfur-containing water in this source can be helpful in the treatment of leg ulcers, tinea versicolor, tineacorporis, and tinea capitis.
Dermatophyte infection caused by Nannizzia gypsea: A rare case report from Madagascar We report a rare case of dermatophyte infection of the glabrous skin (Tineacorporis) caused by Nannizzia gypsea (formerly Microsporum gypseum). A 22-year-old Malagasy female who reported close contact reportedly with cats, presented a single round lesion with a peripheral, active, squamous and pruriginous inflammatory bead. Morphologic species identification was confirmed by sequencing the internal
Skin rash in a 2-week-old infant. We presented a case of a male infant with annular patchy rash on his torso since 2 weeks of age. This was initially diagnosed as tineacorporis but did not respond to oral antifungal treatment. Because of the appearance of the rash and a history of a certain disease in a maternal aunt, we suspected the most probable cause of the rash and the diagnosis was confirmed by laboratory testing. Furthermore, laboratory screening of the mother, who was asymptomatic
if a 'herald patch' (an erythematous, slightly raised oval patch, 2–10 cm in diameter and with scale at the margin) appeared a few days or weeks before the generalized eruption. It usually occurs on the trunk but can occur anywhere on the body. Other conditions that may present in a similar way include: Guttate psoriasis Discoid (nummular) eczema Drug reactions HIV seroconversion Lichen planus Pityriasis lichenoides Pityriasis versicolor Polymorphic eruption of pregnancy Secondary syphilis Tineacorporis (...) on for more information. Tineacorporis This is characterized by well-demarcated, scaly, annular, erythematous papules or plaques, which gradually enlarge over time. The borders may be raised or scaly with central clearance. See the CKS topic on for more information. Other rashes with annular lesions, including: Erythema annulare centrifugum — expanding lesions with central clearing and scaling at the trailing edge, most commonly affecting the trunk, buttocks, and legs. Erythema migrans (Lyme disease
commonly occur on sebum-rich areas of the skin, particularly the back, chest, and upper arms. Macules and patches are usually asymptomatic, but mild itch sometimes occurs. The diagnosis can be confirmed by microscopy of skin scrapings, although this is not usually necessary. Disorders that may present similarly include vitiligo, pityriasis alba, psoriasis, tineacorporis, seborrhoeic dermatitis, pityriasis rosea, erythrasma, and secondary syphilis. Initial management of pityriasis versicolor is the use (...) disorders that may present similarly include: Vitiligo — especially in dark-skinned people with hypopigmented lesions. For more information, see the CKS topic on . Psoriasis — particularly guttate psoriasis, a chronic inflammatory condition that usually affects children and young adults, and is characterized by small scaly skin papules, which may be pink or red, and may occur anywhere on the body. For more information, see the CKS topic on . Tineacorporis — a dermatophyte infection of the skin, usually
in the winter. The body site most commonly affected was the face. Tineacorporis was the most common subtype of dermatophytosis caused by T. tonsurans. Herein, we demonstrate that the prevalence of infection with T. tonsurans remain constant throughout the study period in Korea.
produced favorable clinical and mycological results in clinical trials for tineacorporis and tinea cruris. Across trials, adverse events consisted mainly of localized reactions following application. The development of a new antifungal agent is timely due to mounting resistance among existing treatments. Because luliconazole requires a short duration of treatment, it may assist in reducing disease recurrence as a result of patient nonadherence. (...) A critical appraisal of once-daily topical luliconazole for the treatment of superficial fungal infections Luliconazole is a novel imidazole derivative, which has demonstrated in vitro efficacy against dermatophytes and Candida. The results from Phase III trials show that luliconazole 1% cream applied once daily for 2 weeks successfully resolved the clinical signs and symptoms as well as eradicated the pathologic fungi, which cause tinea pedis. A 1-week treatment with luliconazole 1% cream also
corporis), nail (tinea unguium), and hand (tinea manuum). The identification of evolutionary relationship between these three genera of dermatophyte is epidemiologically important to understand their pathogenicity. Mitochondrial DNA evolves more rapidly than a nuclear DNA due to higher rate of mutation but is very less affected by genetic recombination, making it an important tool for phylogenetic studies. Thus, here we present a novel scheme to identify the conserved coil functional residues (...) Computational analysis of conserved coil functional residues in the mitochondrial genomic sequences of dermatophytes Dermatophyte is a group of closely related fungi that have the capacity to invade keratinized tissue of humans and other animals. The infection known as dermatophytosis, caused by members of the genera Microsporum, Trichophyton, and Epidermophyton includes infection to the groin (tinea cruris), beard (tinea barbae), scalp (tinea capitis), feet (tinea pedis), glabrous skin (tinea